BGC0000665: xiamycin biosynthetic gene cluster from Streptomyces sp. HKI0576
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Location: 1 - 21,259 nt. (total: 21,259 nt).
This entry is originally from NCBI GenBank HE815466.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Terpene
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000665
Short description xiamycin biosynthetic gene cluster from Streptomyces sp. HKI0576
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Terpene (Sesquiterpene/Unknown)
  • Alkaloid (Indole/benzopyrrole)
Loci NCBI GenBank: HE815466.1
Compounds
  • xiamycin
Species Streptomyces sp. HKI0576 [taxonomy]
References
Chemical products information
xiamycin
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C23H25N1O3
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CCH63727.1
  • xiaA
 1 - 1002 (+) XiaA protein
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  • CCH63728.1
  • xiaB
 1015 - 2832 (+) XiaB protein
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  • CCH63729.1
  • xiaC
 2829 - 3980 (+) XiaC protein
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  • CCH63730.1
  • xiaD
 4412 - 5134 (+) XiaD protein
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  • CCH63731.1
  • xiaE
 5127 - 5879 (-) XiaE protein
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  • CCH63732.1
  • xiaF
 5946 - 7145 (-) XiaF protein
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  • CCH63733.1
  • xiaG
 7142 - 7531 (-) XiaG protein
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  • CCH63734.1
  • xiaH
 7534 - 9327 (-) XiaH protein
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  • CCH63735.1
  • xiaI
 9324 - 9557 (-) Indole oxygenase
  • Tailoring (Oxidation)
Activity assay
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  • CCH63736.1
  • xiaJ
 9583 - 10752 (-) XiaJ protein
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  • CCH63737.1
  • xiaK
 10906 - 12036 (-) XiaK protein
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  • CCH63738.1
  • xiaL
 12059 - 14227 (-) XiaL protein
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  • CCH63739.1
  • xiaM
 14256 - 15263 (-) Cytochrome P450
  • Tailoring (Oxidation)
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  • CCH63740.1
  • xiaN
 15358 - 18309 (-) XiaN protein
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  • CCH63741.1
  • xiaO
 18482 - 21259 (+) XiaO protein
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Terpene-specific information
Carbon count subclass Sesquiterpene
Structural subclass Unknown
Isoprenoid precursor FPP
Prenyltransferases xiaM
Terpene synthases/cyclases xiaE
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: ZUAEFEJPIFGA5SNZGJWBG3IU, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected gene identifiers
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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