LOCUS       BGC0000675              4976 bp    DNA     linear   CON 02-SEP-2008
DEFINITION  Streptomyces clavuligerus ATCC 27064 supercont1.31 genomic scaffold,
            whole genome shotgun sequence.
ACCESSION   BGC0000675
VERSION     BGC0000675
KEYWORDS    .
SOURCE      Streptomyces clavuligerus
  ORGANISM  Streptomyces clavuligerus
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     The CDS were annotated to begin and end with complete codons.
            Consequently, incomplete CDSs were not extended to the ends of the
            nucleotide sequences.
            Annotation was added to the scaffolds in August 2008.
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 20:14:15
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4976
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..4976
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[2176:3433]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2177..3433
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..4976
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..4976
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000675"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..4976
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(1..828)
                     /locus_tag="SSCG_03686"
     CDS             complement(1..828)
                     /codon_start=1
                     /locus_tag="SSCG_03686"
                     /product="methyltransferase type 12"
                     /protein_id="EDY50539.1"
                     /transl_table=11
                     /translation="MTAAGDDGIGTPTSARSGYGAGLFDHRRRLEVQRLRALEAYNDPA
                     TQSVILARGVQPGWRCLELGGGAGSIARWLAAHSAPGEVVVTDLDTRLLPRGIPNLTVL
                     RHDVVHDDFPAASFDLVHARALLEHLPKPTDVLAKMVRWTAPGGWVCVDDLISIRPPGG
                     PRDAHQRCWNALVTLAEGTMRIDQHWAATLPRLFAAQGLTDIGVHCTPGLVGGSGNATE
                     FIRIALEQLGTTLVERCLITDRDLAEGRDLLADPHYSDLVTITFSAWGRRPST"
     gene            complement(825..2180)
                     /locus_tag="SSCG_03687"
     CDS             complement(1377..2180)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 198.6; E-value: 3.2e-60)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SSCG_03687"
                     /note="truncated CDS"
                     /product="truncated pentalenene C13 hydroxylase"
                     /protein_id="EDY50540.1"
                     /sec_met_domain="p450 (E-value: 5e-27, bitscore: 83.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPTYTMAQAPGALPVLGHAAAFARRPLDFIRELPDHGDLVRVRL
                     GPLTAHVVCHPDLLHRVLAEDRVFDKGGPVFETFRKTAGNGLLGCPARDHRRQRRLVQP
                     AFHRSRLPGYSAAMAEEIAALTEPWRPGQTLDVPALMYRLTTAVTTRCLFASAAQAADL
                     PSLHESVDIVTQGIARRAMLPVPALHRLPTPANRRYQRTQRYLRHLTDTLIDSYRTQGT
                     DQGDLLSMLLAPQDDGGPGLTGTEIHDQILTFLLAGIDTTAILLS"
     gene            complement(2177..3433)
                     /locus_tag="SSCG_03688"
     CDS             complement(2177..3433)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Terpene synthase/cyclase metal-binding domain
                     protein (Score: 258.5; E-value: 1.6e-78)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SSCG_03688"
                     /product="hypothetical protein"
                     /protein_id="EDY50541.1"
                     /sec_met_domain="Terpene_synth_C (E-value: 5e-14, bitscore:
                     40.7, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLNHSDLMFYCPVDDLPHPAASGVNDRTLDWASGQGIPTADRDA
                     GRLRAMAPGLLAARIAPDARGPVLDAFADHHTWLFAFDDEYCDRADGSGITEWASFLAR
                     LHRVVETGESALLPGNPYGLALRDIACRLSTYTTPAQLAEWLEALRSYFAALVWERSRR
                     RDDDRLQSLDDYLLLRLRNGAMHTSITLLDTVNGYVLPRELRETPGVRALVEMTALLVS
                     VDNDILSHHKESTSGTREANLLDVLGRTGHTTPGEAVAQAVALRNEIMRQFVRVAERVR
                     TPAAVPELYRFTTGLARWIRANLDFSLTTTRYTGPVTERAALSPHEVPPLSGQGPAPAR
                     SDVIGWWWRIPEPLPEPGSDGADTPVRKRRAGDRPPTAGRGGAPHHQRTGPPPPVLPGG
                     ITASRSSGLQQSTWRREHR"
     gene            complement(3424..3621)
                     /locus_tag="SSCG_03689"
     CDS             complement(3424..3621)
                     /codon_start=1
                     /locus_tag="SSCG_03689"
                     /product="hypothetical protein"
                     /protein_id="EDY50542.1"
                     /transl_table=11
                     /translation="MPQDIAAFIPFPTRLGPGTGRAAAGHLRRPRFFGLLPRTHHPTAE
                     DQAPPGWPESSSPCARSTCP"
     gene            complement(3639..4976)
                     /locus_tag="SSCG_03690"
     CDS             complement(3639..4976)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034:cytochrome P450 (Score: 365.4; E-value:
                     7.4e-111)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="SSCG_03690"
                     /product="cytochrome P450 hydroxylase"
                     /protein_id="EDY50543.1"
                     /sec_met_domain="p450 (E-value: 8.4e-66, bitscore: 210.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAPPVAPGRLPVLGHLVAMLRDPLGFMASLPAVAEVVTIYVGTR
                     PVHVANSLDLVQSMLVTEADSFQRGLLFEKAEKVVGPGLTMVEGEAHRRQRKLVQPAFS
                     PRRIEQYTQTMIEAAEAGVGSWRPGRRMDADRVMYDLGMDVFTRVLFRGALDGASADLV
                     KQATSGIMAGMVAHSLYPAQWLEKVPIPLNRRFRRGDAQMTEVVDRIIHHYRQGGTADH
                     DGAAILDALMAENERASGRPLDSVELRTEVIHLLVAGAEGPGASLAWLFHELSRHPDVE
                     RQLVEELDAVFGDGPLTVAGLAGLTFTRAVVKESLRVHAPTWLLTRRALKAVALGGHRI
                     PAGGEVAFSLTALHRTAPQYDDPGRFDPARWLDGRTARLPRSAYMPFGTGRHRCVGDHF
                     TLQVVLVCAVTIARRWRLVPCPGIRVRERPVALVRPSGLLMDVAAR"
ORIGIN
        1 ctacgtactg gggcgtcggc cccaggcgga gaaggtgatg gtgaccaggt cgctgtagtg
       61 cgggtccgcc agcaggtcac ggccttcggc gaggtcacgg tcggtgatga ggcaccgttc
      121 gaccagggtc gttccgagct gttcgagcgc gatccggatg aactcggtgg cgttgccgct
      181 ccctcccacc aggccggggg tgcagtggac gccgatgtcg gtcaggccct gggcggcgaa
      241 cagccgcggc agggtggcgg cccagtgctg gtcgatccgc atggtgccct ccgcgagggt
      301 gacgagcgcg ttccagcagc gctgatgggc gtcgcgcggg ccgccgggcg ggcgtatgga
      361 gatcaggtcg tccacgcaca cccagcctcc gggggcggtc cagcggacca ttttggcgag
      421 aacatccgtg ggtttgggca ggtgttcgag cagggcgcgg gcgtggacga ggtcgaagga
      481 ggccgcgggg aagtcgtcgt ggaccacgtc gtggcgcagg acggtgaggt tgggtatgcc
      541 gcggggcagc agccgggtgt cgaggtcggt gacgacgacc tctccggggg cgctgtgtgc
      601 ggcgagccag cgggcgatgg accctgctcc gccgccgagt tcgaggcagc gccagcccgg
      661 ctggacaccc cgggccagga tgaccgactg ggtcgcgggg tcgttgtatg cctccagggc
      721 acgcagccgc tgtacctcca ggcggcgacg gtggtcgaag agtcccgcgc cgtacccgct
      781 gcgggcgctg gtgggggtgc ctatgccgtc gtctcctgcg gccgtcacgg cgctgtgccc
      841 gcaccggagc cgcttcgttc ccgcaggcgc atggtgagtt ttttgggctg gagggtgatg
      901 tggcgggcgg ggcggacggg tggtccgggg gtggggtcga gctgccagcg ggtggcgatg
      961 gtggcgaggg cgagggtggt ttcgttgagg gcgaaggtct cggcgatgca tttacggggg
     1021 ccgctgctga acggcaggtg ggtgccgggt gggggtttgg gggcgttcag ccatcggtcg
     1081 gggtcgaagc ggtcggggtg ggggtagagg tcggcgcggc ggtggatctg gtaggcgctg
     1141 aacatgatgg tgctgcgggc gggcagcggg tgtccgccga gttcggtgtc ggtggtgacg
     1201 gtgcgggtga agagccaggc ggaggggtag aggcgcagcg tctcctggat gatccggccg
     1261 gtgagttcga gcgcggggag gtcgtcgtgc tgggcggggc ggccatcgag cacggtgtcg
     1321 acctcggtgt gcagccggtc gcggatgtcg gggtgggtgc cgagcagatg ccagactcag
     1381 gagagcagga tggccgtggt gtcgatgccc gcgaggagga aggtgaggat ctggtcgtgg
     1441 atctcggtgc cggtcagccc cggtccgccg tcgtcctggg gagccagcag catcgacagc
     1501 agatcgccct ggtcggtgcc ttgtgtccgg tagctgtcga tcagggtgtc ggtgagatgc
     1561 cgcaggtacc gttgtgtccg ctggtagcgg cggttggccg gggtggggag ccggtggagg
     1621 gcggggacgg gcagcatggc acgccgggcg atgccctggg tgacgatgtc gacgctctcg
     1681 tgcagggagg gcaggtcggc cgcctgtgcg gcggaggcga acaggcaccg ggtggtcacg
     1741 gcggtggtga gccggtacat cagagcgggg acgtcgaggg tctggccggg ccgccagggc
     1801 tcggtgagcg ccgcgatctc ctcggccatg gcggccgagt agccgggcag gcgcgagcga
     1861 tggaaagcgg gctggaccag tctgcgctgc ctgcggtggt cgcgggcggg acagccgagc
     1921 aggccgttgc ccgcggtctt gcggaaggtc tcgaagaccg gcccgccctt gtcgaagaca
     1981 cggtcctcgg ccagcacccg gtggagcaga tcgggatggc agaccacatg ggccgtcagc
     2041 gggcccagcc ggacccgcac caggtccccg tgatcgggca gctcccggat gaagtccagc
     2101 ggccggcggg cgaacgcggc ggcatggccg agcacgggca gcgcgcccgg cgcctgcgcc
     2161 atcgtgtagg tggggttcac cggtgctcac gcctccatgt cgactgctgc aacccggatg
     2221 accgactggc cgtgattccg cccgggagaa cgggtggcgg tggccccgtc cgctggtggt
     2281 ggggagcgcc gcccctgcct gccgtgggtg ggcgatcccc ggcacggcgt ttcctcaccg
     2341 gcgtgtcagc gccatcggag cccggctcgg ggaggggctc cggtatccgc caccaccagc
     2401 cgatcacgtc cgaccgggcg ggggcgggcc cctgccccga caggggagga acctcatgcg
     2461 ggctgagggc ggcgcgttcg gtgaccggac cggtgtagcg ggtggtggtg aggctgaagt
     2521 ccaggttggc ccgtatccag cgggcgagac ccgtggtgaa acggtacagc tccgggacgg
     2581 cggcgggggt ccggactcgt tcggccacgc gcacgaattg acgcatgatc tcattgcgca
     2641 gggcgacggc ctgggctacg gcttccccgg gggtggtgtg ccccgtccgg ccgagcacat
     2701 cgaggagatt ggcctcccgg gtcccgctcg tggactcctt gtggtgcgag aggatgtcgt
     2761 tgtccaccga gacgagaagc gcggtcatct cgaccagggc gcgtacgccc ggtgtttccc
     2821 gcagctcgcg tggcaggacg tagccgttga cggtgtccag gagggtgatg ctggtgtgca
     2881 tcgcgccgtt gcggaggcgg agcagcagat agtcgtcgag gctctggagc cggtcgtcgt
     2941 cgcggcggcg ggagcgttcc cagaccaggg cggcgaagta ggaccgcagg gcttcgagcc
     3001 attcggcgag ctgggccggt gtcgtgtacg tggagagccg gcaggcgatg tcacgcaggg
     3061 cgaggccgta gggattgccc ggcagcagcg cgctctcgcc ggtctccacc acccggtgca
     3121 gccgggccag gaagctcgcc cactcggtga tgccggaacc gtcggccctg tcgcagtact
     3181 cgtcgtcgaa ggcgaagagc caggtgtggt ggtccgcgaa agcgtccagc accgggcccc
     3241 gggcgtccgg ggcgatacgg gccgccagca gacccggcgc catcgcccgc agccggcccg
     3301 cgtcccggtc cgccgtgggt atcccctgcc cggacgccca gtcgagcgta cggtcattga
     3361 cacccgacgc cgccggatgc ggaagatcgt ccacagggca gtagaacatc agatcgctgt
     3421 ggttcaggga catgtcgacc tcgcacaggg tgatgaggat tcaggccacc cagggggtgc
     3481 ttggtcctcg gcggtggggt ggtgggtccg gggcaggagg ccgaagaacc gcggccggcg
     3541 gagatgaccg gcggcggccc ggccggtgcc cgggccgagc cgtgtgggaa aggggatgaa
     3601 tgcggcgatg tcctggggca taccgtgcgc ctcccgccct accgggccgc cacgtccatg
     3661 aggagaccac ttggccgcac cagcgccacc ggcctctccc ggacacggat tccggggcac
     3721 ggcacgagcc gccaccgccg ggcgatggtc acggcacaga ccaggaccac ctggagggtg
     3781 aagtggtcgc ccacgcatcg gtgcctgccg gttccgaagg gcatgtacgc gctgcgcggc
     3841 agacgcgccg tccggccgtc cagccagcgc gccgggtcga agcgcccggg gtcgtcgtac
     3901 tgcggcgcgg tgcggtgcag cgcggtgagg ctgaaagcga cctcgccacc ggccggaatg
     3961 cggtgcccac cgagggcgac ggccttcagg gcacggcggg tcagcagcca ggtcggggcg
     4021 tggacgcgca gggattcctt caccacggcc cgggtgaagg tgagaccggc gagccccgcc
     4081 acggtgaggg ggccgtcccc gaagacggcg tcgagttcct ccaccagctg ccgttcgacg
     4141 tcggggtgcc ggctcagctc gtggaacagc caggccaggg acgcgccggg cccttcggcg
     4201 ccggcgacca ggagatgaat gacctcggtc cgcagttcca cggagtccag gggccgaccg
     4261 ctcgcccgct cgttctcggc catcaacgcg tcgaggatcg ccgccccgtc gtggtcggcc
     4321 gtgccgccct gccggtagtg gtggatgatc cggtcgacca cctcggtcat ctgcgcgtcg
     4381 ccacgccgga accggcgatt gagcgggatc ggcaccttct ccagccactg cgccggatag
     4441 agcgagtgcg cgaccatccc ggccatgatg ccggaggtcg cctgcttcac caggtccgcc
     4501 gatgcgccgt cgagcgcgcc gcggaacagt acccgggtga agacgtccat gccgaggtcg
     4561 tacatcaccc ggtccgcgtc catcctccgg cccggccgcc aggagccgac tccggcctcc
     4621 gccgcctcga tcatcgtctg ggtgtactgc tcgatccggc gcgggctgaa cgccggctgg
     4681 accagcttgc gctgcctcct gtgcgcctcc ccctcgacca tggtcagacc gggacccacg
     4741 accttctcgg ccttctcgaa caacagtccg cgctgaaagc tgtcggcctc ggtgaccagc
     4801 atggactgga ccagatcgag cgagttggcg acatggaccg gccgcgtccc gacatagatg
     4861 gtgaccacct cggccacggc cggcaaggac gccatgaacc cgagaggatc acggagcatg
     4921 gcgacgagat gccccaggac cgggagccgc cccggagcga cgggcggcgc gggcag
//
