BGC0000676: aphidicolin biosynthetic gene cluster from Phoma betae
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Location: 1 - 15,629 nt. (total: 15,629 nt).
This entry is originally from NCBI GenBank AB114137.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Terpene
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000676
Short description aphidicolin biosynthetic gene cluster from Phoma betae
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Terpene (Diterpene/Unknown)
Loci NCBI GenBank: AB114137.1
Compounds
  • aphidicolin
  • aphidicolan-16β-ol
  • 3-deoxyaphidicolin
  • 17-deoxyaphidicolin
Species Phoma betae [taxonomy]
References
Chemical products information
aphidicolin
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C20H34O4
Chemical database entries
NPAtlas
PubCHEM
ChEBI
ChEMBL
ChemSpider
aphidicolan-16β-ol
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C20H34O1
Chemical database entries
PubCHEM
ChEBI
ChemSpider
3-deoxyaphidicolin
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C20H34O3
Chemical database entries
NPAtlas
PubCHEM
ChemSpider
17-deoxyaphidicolin
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C20H34O3
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAD29970.1
  • PbGGS
 622 - 1653 (-) geranylgeranyldiphosphate synthase
  • Precursor biosynthesis
Activity assay
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  • BAD29971.1
  • ACS
 3293 - 6300 (+) aphidicolan-16b-ol synthase
  • Scaffold biosynthesis
Activity assay
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  • BAD29972.1
  • PbP450-1
 6699 - 8429 (+) P450 monooxygenase 1
  • Tailoring (Hydroxylation)
Activity assay
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  • BAD29973.1
  • PbTP
 8957 - 10846 (-) transporter protein
  • Transport
Sequence-based prediction
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  • BAD29974.1
  • PbP450-2
 11482 - 13230 (+) P450 monooxygenase 2
  • Tailoring (Hydroxylation)
Activity assay
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  • BAD29975.1
  • PbTF
 13451 - 14838 (-) transcription factor
  • Regulation
Sequence-based prediction
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Terpene-specific information
Carbon count subclass Diterpene
Structural subclass Unknown
Isoprenoid precursor GGPP
Terpene synthases/cyclases PbGGS
Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: 2KYB26PGYAPUVXC56KYVWB44, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Fix terpene synthase gene ID
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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