BGC0000676: aphidicolin biosynthetic gene cluster from Phoma betae
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Location: 1 - 15,629 nt. (total: 15,629 nt).
This entry is originally from NCBI GenBank AB114137.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000676
Short description aphidicolin biosynthetic gene cluster from Phoma betae
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • terpene (Diterpene)
Loci
AB114137.1
via Heterologous expression
Compounds
  • aphidicolin
  • aphidicolan-16β-ol
  • 3-deoxyaphidicolin
  • 17-deoxyaphidicolin
Species Phoma betae [taxonomy]
References
Chemical products information
aphidicolin Evidence:
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C20H34O4
Chemical database entries
NPAtlas
PubCHEM
ChEBI
ChEMBL
ChemSpider
aphidicolan-16β-ol Evidence:
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C20H34O1
Chemical database entries
PubCHEM
ChEBI
ChemSpider
3-deoxyaphidicolin Evidence:
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C20H34O3
Chemical database entries
NPAtlas
PubCHEM
ChemSpider
17-deoxyaphidicolin Evidence:
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C20H34O3
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAD29970.1
  • PbGGS
 622 - 1653 (-) geranylgeranyldiphosphate synthase
  • Precursor biosynthesis
  • Activity assay
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  • BAD29971.1
  • ACS
 3293 - 6300 (+) aphidicolan-16b-ol synthase
  • Scaffold biosynthesis
  • Activity assay
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  • BAD29972.1
  • PbP450-1
 6699 - 8429 (+) P450 monooxygenase 1
  • Tailoring
  • Activity assay
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  • BAD29973.1
  • PbTP
 8957 - 10846 (-) transporter protein
  • Transport
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  • BAD29974.1
  • PbP450-2
 11482 - 13230 (+) P450 monooxygenase 2
  • Tailoring
  • Activity assay
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  • BAD29975.1
  • PbTF
 13451 - 14838 (-) transcription factor
  • Regulation
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Biosynthesis information
Annotation changelog

Entry version: 4

Date
Changes
Submitters
Reviewers
2022-10-07
Update chemical activity to schema version 2.11
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 3

Date
Changes
Submitters
Reviewers
2022-09-15
Fix terpene synthase gene ID
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 2

Date
Changes
Submitters
Reviewers
2019-10-16
Migrated from v1.4
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2019-10-16
Updated compound(s) information (NPAtlas curation)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 1

Date
Changes
Submitters
Reviewers
2015-06-12
Submitted
  • (ID: 2KYB26PGYAPUVXC56KYVWB44)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
Similar known gene clusters from MIBiG 4.0
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