LOCUS       BGC0000683              1008 bp    DNA     linear   BCT 04-FEB-2015
DEFINITION  Streptomyces avermitilis MA-4680 = NBRC 14893 DNA, complete genome.
ACCESSION   BGC0000683
VERSION     BGC0000683
KEYWORDS    .
SOURCE      Streptomyces avermitilis MA-4680 = NBRC 14893
  ORGANISM  Streptomyces avermitilis MA-4680 = NBRC 14893
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     [WARNING] On Mar 24, 2016 this sequence was replaced by BA000030.4.
            On Jun 15, 2007 this sequence version replaced BA000030.2.
            This work was done in collaboration with Haruo Ikeda(*1), Jun
            Ishikawa(*2), Akiharu Hanamoto(*3), Chigusa Takahashi(*3), Mayumi
            Shinose(*3), Hiroshi Horikawa(*4), Hidekazu Nakazawa(*4), Tomomi
            Osonoe(*4), Norihiro Kushida(*4), Hisashi Kikuchi(*4), Tadayoshi
            Shiba(*5), Yoshiyuki Sakaki(*6,*7), Masahira Hattori(*1,*7)
            and Satoshi Omura(*1,*3).
            Final finishing process and all annotation were done by H. Ikeda
            and J. Ishikawa.
            *1 Kitasato Institute for Life Sciences, Kitasato University *2
            National Institute of Infectious Diseases
            *3 The Kitasato Institute
            *4 National Institute of Technology and Evaluation *5 School of
            Science, Kitasato University
            *6 Institute of Medical Science, University of Tokyo *7 RIKEN,
            Genomic Sciences Center
            All the annotated genes identified are available from following
            urls.
            http://avermitilis.ls.kitasato-u.ac.jp.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:02:50
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            1..1008
                     /gene="tpc1"
                     /locus_tag="SAV_76"
     protocluster    1..1008
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[0:1008]"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1..1008
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     cand_cluster    1..1008
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Terpene_synth or Terpene_synth_C or
                     phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7
                     or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..1008
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000683"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..1008
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(Terpene_synth or Terpene_synth_C or phytoene_synt
                     or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps
                     or fung_ggpps2 or trichodiene_synth or TRI5)"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             1..1008
                     /codon_start=1
                     /gene="tpc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: Terpene_synth_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Terpene synthase/cyclase metal-binding domain
                     protein (Score: 279.4; E-value: 7.3e-85)"
                     /gene_kind="biosynthetic"
                     /locus_tag="SAV_76"
                     /note="PF03936: Terpene synthase family, metal binding
                     domain"
                     /product="putative terpene cyclase"
                     /protein_id="BAC67785.1"
                     /sec_met_domain="Terpene_synth_C (E-value: 3e-21, bitscore:
                     62.1, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQDIDFGLPAPAGISPGLEATRRHNLGWVRRLGLVGDGPSLAWY
                     TSWDMPRLAACGFPHARGAALDLCADAMAFFFVFDDQFDGPLGRDPARAARVCRRLTGI
                     VHGAGPGPGADACSAAFADVWARSTDGAHPGWVARTAHEWEYYFAAQAHEAINRLRGTP
                     GDMESYLQVRRGIAGTDLPLSLGERAAGITVPAAAFHSPQLRIMREAAIDVTLMCNDVY
                     SLEKEEARGDMDNLVLVIEHARRCTRDEAVTAARGEVARRVIRFEQLAREVPALCAQLG
                     LSAVERAHVDTYLGVMEAWMSGYHAWQTQTRRYTGAPHVLPSTGPGYFDEVLPT"
ORIGIN
        1 atgccccagg acatcgactt cggcctcccc gcgcccgcgg ggatcagccc cggcctcgag
       61 gccacacgcc ggcacaacct cggctgggtg cgccgtctgg gtttggtcgg cgacggaccg
      121 tccctcgcct ggtacacctc ctgggacatg ccgcgtctgg ccgcctgcgg cttcccccac
      181 gcccggggcg ccgcgttgga cctgtgcgcg gatgcgatgg cgttcttctt cgtcttcgac
      241 gaccagttcg acggccctct cggccgggat ccggcccggg ctgcccgcgt ctgccggcgg
      301 ctgaccggca tcgttcacgg cgccggccca gggcctggag cggacgcgtg ctcggcggcg
      361 ttcgccgacg tgtgggcccg cagcaccgac ggcgcccacc cgggctgggt ggcgcgtacc
      421 gcgcacgagt gggagtacta cttcgccgcc caggcccacg aggcgatcaa ccggctccgc
      481 ggcacccccg gcgacatgga gtcctacctt caggtccgcc ggggcatcgc cggcaccgat
      541 ctgcctctct ccctgggcga gagagccgcc gggatcaccg tcccggcggc cgcgttccac
      601 agcccgcagc tgcggatcat gcgggaagcg gccatcgacg tcaccttgat gtgcaacgac
      661 gtgtactccc tcgaaaagga ggaagcacgc ggtgacatgg acaacctcgt cctcgtcatc
      721 gaacacgccc ggcgctgcac ccgcgacgaa gccgtcaccg cggcccgcgg ggaagtcgcc
      781 cggcgtgtca tccggttcga gcagctggcc cgggaggtac ccgccctgtg cgcccagctc
      841 gggctgagcg ccgtggagcg ggcccacgtc gacacctacc tgggtgtcat ggaggcctgg
      901 atgagcggat accacgcctg gcagacccag acacggcgct acaccggcgc gccacacgtc
      961 ctgcccagca ccggccccgg gtacttcgac gaggtcctgc ccacgtga
//
