BGC0000686: helvolic acid biosynthetic gene cluster from Aspergillus fumigatus Af293
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Location: 3,892,066 - 3,908,342 nt. (total: 16,277 nt).
This entry is originally from NCBI GenBank CM000172.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000686
Short description helvolic acid biosynthetic gene cluster from Aspergillus fumigatus Af293
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • terpene (Unknown)
Loci
CM000172.1
3892066 - 3908342
via
Compounds
  • helvolic acid
Species Aspergillus fumigatus Af293 [taxonomy]
References
Chemical products information
helvolic acid Evidence:
Copy SMILES
C33H44O8
Chemical database entries
PubCHEM
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AFUA_4G14770
  • EAL89318.1
 3892066 - 3894273 (-) squalene-hopene-cyclase, putative
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    • AFUA_4G14780
    • EAL89317.1
    		 3894708 - 3896450 (-) cytochrome P450 monooxygenase, putative
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      • AFUA_4G14790
      • EAL89316.1
      		 3897029 - 3898552 (+) cytochrome P450 monooxygenase, putative
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        • AFUA_4G14800
        • EAL89315.1
        		 3898588 - 3899361 (-) short chain dehydrogenase, putative
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          • AFUA_4G14810
          • EAL89314.2
          		 3899642 - 3901165 (+) cytochrome P450 monooxygenase, putative
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            • AFUA_4G14820
            • EAL89313.1
            		 3901590 - 3903026 (+) transferase family protein
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              • AFUA_4G14830
              • EAL89312.1
              		 3903216 - 3904730 (+) cytochrome P450 monooxygenase, putative
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                • AFUA_4G14840
                • EAL89311.1
                		 3905132 - 3906523 (+) transferase family protein
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                  • AFUA_4G14850
                  • EAL89310.1
                  		 3906552 - 3908342 (-) extracellular 3-ketosteroid 1-dehydrogenase, putative
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                    Biosynthesis information
                    Annotation changelog

                    Entry version: next

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2024-08-10
                    MIBiG v4 annotathon
                    • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 2

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2019-10-16
                    Migrated from v1.4
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    2019-10-16
                    Updated compound(s) information (NPAtlas curation)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                    Entry version: 1

                    Date
                    Changes
                    Submitters
                    Reviewers
                    2015-06-12
                    Submitted
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                    • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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