Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000686.1:
Cluster 1Terpene116277

BGC0000686, helvolic acid biosynthetic gene cluster from Aspergillus fumigatus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: helvolic acid
PubChem ID: 3002143
SMILES string: Copy to clipboard
Molecular formula: C33H44O8
Average molecular mass: 568.707 Da

Class-specific details

Biosynthetic class(es):
Terpene

Gene cluster description

helvolic acid (BGC0000686). Gene Cluster 1. Biosynthetic class = Terpene. GenBank CM000172, positions 3892066-3908342. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Literature references

1. Mitsuguchi H et al. (2009) Biosynthesis of steroidal antibiotic fusidanes: functional analysis of oxidosqualene cyclase and subsequent tailoring enzymes from Aspergillus fumigatus. J Am Chem Soc 131(18):6402-11. doi: 10.1021/ja8095976.