LOCUS       BGC0000692             39979 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptoalloteichus hindustanus partial apramycin biosynthesis gene
            cluster, type strain DSM 44523T.
ACCESSION   BGC0000692
VERSION     BGC0000692
KEYWORDS    .
SOURCE      Streptoalloteichus hindustanus
  ORGANISM  Streptoalloteichus hindustanus
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Streptoalloteichus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:03:33
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(<1..516)
                     /codon_start=1
                     /db_xref="InterPro:IPR003737"
                     /db_xref="UniProtKB/TrEMBL:Q2MEY8"
                     /function="putative deacetylation in apramycin
                     biosynthesis"
                     /gene="aprN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.1c"
                     /note="conserved in other aminoglycoside gene clusters,
                     member of the LmbE proteinfamily (COG2120)"
                     /product="putative aminoglycoside N-acetylhexosaminyl
                     deacetylase"
                     /protein_id="CAI47636.1"
                     /sec_met_domain="PIG-L (E-value: 7e-23, bitscore: 72.8,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPENFAFAGNLLLVSPHPDDIAYSCGGVVAAHLGEATATLLTVFG
                     RSEWTVSPRLAAEGQEAVSRVRAEEDRRYCDAHGIAYTLLDFPDASLRGYDDEGELTAR
                     VADDPLTDEVVDVLAEAVRAAAPDLVLAPAGMGDHIDHLMVHEALRRVDHEFSTLYYED
                     IPYSAHHEI"
     gene            complement(<1..527)
                     /gene="aprN"
                     /locus_tag="ShinN01.1c"
     source          1..39979
                     /db_xref="taxon:2017"
                     /mol_type="genomic DNA"
                     /organism="Streptoalloteichus hindustanus"
                     /strain="type strain:DSM 44523"
     subregion       1..39979
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000692"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..39979
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="2dos"
                     /region_number="1"
                     /rules="((DOIS or DHQ_synthase or ValA or salQ) and
                     DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     misc_feature    complement(481..483)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     regulatory      complement(522..527)
                     /gene="aprN"
                     /locus_tag="ShinN01.1c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(632..2512)
                     /gene="aprW"
                     /locus_tag="ShinN01.2c"
     CDS             complement(632..2512)
                     /codon_start=1
                     /db_xref="GOA:Q2MEY7"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR017940"
                     /db_xref="UniProtKB/TrEMBL:Q2MEY7"
                     /function="putative export of aminoglycoside"
                     /gene="aprW"
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     259.9; E-value: 2.8e-79)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 367.8; E-value:
                     1.7e-111)"
                     /gene_kind="transport"
                     /locus_tag="ShinN01.2c"
                     /product="putative ABC-type aminoglycoside exporter"
                     /protein_id="CAI47637.1"
                     /transl_table=11
                     /translation="MNQPNTRTSAAEETEAGEPARQEWRGVAAEDHDTLDRHVGRQLQR
                     RSRRLLLDVLRPHRVGAVVALLLAVLDTAAEMARPLLIAAVIDSGIPAAARQDYGPLTW
                     YVAGYLVSSVASAGLTYSFMTLSGRIGQSVLLELRHRLFRQVQRLSLSFHESYTSGKVI
                     SRLTSDLQALSTLLEESIEGLFRAFLSVVTIAVLLVWLDLPLTGVIVLTFVPLLWITAR
                     YRARSHFFYRRTRSAIARVISHFVETMNGIRVVQAYRLEETNSRTMGALNAANQDATVR
                     AGYGLAHSTAGINLIGNTTVALVLLVGGWRIINGHLEVGVLAAYVLYLRKFYDPVDDLA
                     RFANSYASASAALEKISGVLEEEPTVAQPARPVPLHAREATIDFSRVDFRYQSSKDLVL
                     RDVTLRIPAGQTVAIVGETGAGKSTIAKLVARFYDPTGGRVSINGVDLREVADADLRAA
                     TSMITQESFLFSGTVAENIALGRPDASREEIVRAATAIGAHEFITQLPDGYDTDVNKRG
                     GRLSAGQRQLVALARVLLADSAVLILDEATSSMDIATERAVQRALHTTLRGRTALIIAH
                     RLSTVLAADRVLVVEHGRIVEDGPPAQLVESGGKFATLHQAWLASTSASA"
     CDS             complement(2509..4311)
                     /codon_start=1
                     /db_xref="GOA:Q2MEY6"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="InterPro:IPR017871"
                     /db_xref="InterPro:IPR017940"
                     /db_xref="UniProtKB/TrEMBL:Q2MEY6"
                     /function="putative export of aminoglycoside"
                     /gene="aprV"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 508.1; E-value:
                     5.2e-154)"
                     /gene_kind="transport"
                     /locus_tag="ShinN01.3c"
                     /note="possible translational coupling with ORF ShinN01.2c"
                     /product="putative ABC-type aminoglycoside exporter"
                     /protein_id="CAI47638.1"
                     /transl_table=11
                     /translation="MSLQTAPPESVRRKSAIATLWRLKPYFRPEFALLGWALLSALATT
                     ICGLLIPLVIQRVVDGPVAARDMTGLLWTTGGAFLLGALEAAFFLGRHRLVVGPSARIE
                     SRMRAQLYDHLQRLPLAFHDRWHSGQLLSRAVADLTTIVRFPRYALVYLVVNSFTIVVS
                     IGVLCWMSPLLGAAFTVISLPVAVGSIVFEARYKECSLRAQNQLGDLTTRIEESVLGIR
                     VLKAFGRSGQAVRAFRQRAELLRATEISKVRMLGMLTATIVGLPEVALGAVLGIGGYLA
                     ARGSMSAGELVAAVAVVAYLQWPLESIGYLLAEANDAAAATERYFQIVRAEVTVTDPVD
                     PVPLSTPVRGALRVEGVRFRYDGADEELLRGVDLEIRPGETLALVGGAGSGKSTLVGMV
                     SRLYDVTGGRITLDGTDIRRVPLADLRAAVATVFEEPVLFSGTVRDNVRLNRTDVTDDE
                     VREALRVANAESFVAAMPLGLDTEIGEQGFSLSGGQRQRLALARAVVARPALLVMDDPL
                     SALDIHTEAEVEAALRQVLRGVTALVVAHRPSTVQLADRVALLADGRVDAVGTHQDLLR
                     DCPRYRELMAPDDQRTPEAGTARR"
     gene            complement(order(2509..4311,4324..4329))
                     /gene="aprV"
                     /locus_tag="ShinN01.3c"
     regulatory      complement(4324..4329)
                     /gene="aprV"
                     /locus_tag="ShinN01.3c"
                     /regulatory_class="ribosome_binding_site"
     gene            4608..5618
                     /gene="aprU"
                     /locus_tag="ShinN01.4"
     CDS             4608..5618
                     /codon_start=1
                     /db_xref="GOA:Q2MEY5"
                     /db_xref="InterPro:IPR002575"
                     /db_xref="InterPro:IPR011009"
                     /db_xref="UniProtKB/TrEMBL:Q2MEY5"
                     /gene="aprU"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.4"
                     /product="putative apramycin kinase"
                     /protein_id="CAI47639.1"
                     /sec_met_domain="APH (E-value: 9.9e-24, bitscore: 75.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHERRLHFPRNPEAGVKESFLLSGVGLGDSTLVRSLRSGGEMTWL
                     VRSNSGLTPELVVVKRKRDYLSESEFLAHCAVHRRLADAGGPVPGLPASAPDNPVRGPD
                     GALYEIWEWVEGRPVDVASPADLAALGAALAEFHLLADGALDGVDLDPKEPHDRFEKAR
                     FHFPLLAEGLGDAGAEQHRALVAAWTAAHERARRETPLPANVLHGDPCPENVLVTGPGR
                     AVLLDLDDVHPGPAVSDLAWSLTRVGAVVPEGDGFRDRWHAEAVAAVLDGYRSRRPLSA
                     AERAALPHWIVASLCCAASDQLYDYGWKIDTAALPAECDRVLALAEPGGAPLPDA"
     regulatory      7070..7075
                     /gene="aprA"
                     /locus_tag="ShinN01.5"
                     /regulatory_class="ribosome_binding_site"
     gene            7070..8207
                     /gene="aprA"
                     /locus_tag="ShinN01.5"
     CDS             7080..8207
                     /codon_start=1
                     /db_xref="InterPro:IPR007171"
                     /db_xref="InterPro:IPR023131"
                     /db_xref="UniProtKB/TrEMBL:Q2MEY4"
                     /gene="aprA"
                     /locus_tag="ShinN01.5"
                     /protein_id="CAI47640.1"
                     /transl_table=11
                     /translation="MLLLLTCRGSAEIRATHDRTLEFTTDSAISGRASCVVGVDTVLAR
                     GGRVAGPVRITIACGGLEAEVRALASSAWLPGGRAVVRRSGLRLANTMATDADTTAADL
                     PRELVALLARPDAAIEVRVSRDTGRWDGRGSVVLCHAGVDADRLAAELAAADVVVAEDP
                     EARAVAGDGENVVTGPVREQDLLEHGGRVLVLAAEDLPGASVAGLLGEPERFAVECVGL
                     ASPLAVAAASPARGRLLVGDRGKWRELLRSSPESRLALRVPAASLEALFTDAERLRGTR
                     TAALAGATAAASEQPRWGGLATLLADAPRSGDVVCCLDPTPGSGEGDEPEADPVVTALL
                     EQGVPARTVAMALAQRPGWTRKTAYDFVLRHRAPR"
     regulatory      8471..8477
                     /gene="kamB"
                     /locus_tag="ShinN01.6"
                     /regulatory_class="ribosome_binding_site"
     gene            8471..8950
                     /gene="kamB"
                     /locus_tag="ShinN01.6"
     CDS             8483..8950
                     /codon_start=1
                     /db_xref="GOA:Q2MEY3"
                     /db_xref="UniProtKB/TrEMBL:Q2MEY3"
                     /function="resistance"
                     /gene="kamB"
                     /locus_tag="ShinN01.6"
                     /product="16S rRNA methyltransferase"
                     /protein_id="CAI47641.1"
                     /transl_table=11
                     /translation="MERMSAKAAAKPAKGGLPNLLYLWATAEKLPPLTGVGELHVLMPW
                     GSLLRGILGSSPEMLRGLAAVCRPDAAFLVALNLHAWRPPVPEVGEHPEPTPETVDEGL
                     AARYAQAGWQLTDCRYLAAEEVAALETSWTRRLNSSRDRFDVLALTGKINP"
     gene            complement(8940..11282)
                     /gene="aprO"
                     /locus_tag="ShinN01.7c"
     CDS             complement(8940..11282)
                     /codon_start=1
                     /db_xref="GOA:Q2MEY2"
                     /db_xref="InterPro:IPR005195"
                     /db_xref="InterPro:IPR005196"
                     /db_xref="InterPro:IPR008928"
                     /db_xref="InterPro:IPR011013"
                     /db_xref="InterPro:IPR012341"
                     /db_xref="InterPro:IPR017045"
                     /db_xref="UniProtKB/TrEMBL:Q2MEY2"
                     /gene="aprO"
                     /locus_tag="ShinN01.7c"
                     /product="putative phosphorylase or hydrolase"
                     /protein_id="CAI47642.1"
                     /transl_table=11
                     /translation="MTSTASDPNRGPGGQADPGWVIERTAYRRTEDSFYESLFALSNGR
                     IGVRATADFDAGGGWPGFYHARMYARAVTVRRHLVNAPTPAFRAVLVDGVPLAVTADRV
                     TEFRQRLDLRRARQELVVTVRDGQGRHTRIETTTLLPAQFTTTLVQRVAVTPLDHDAPV
                     TVLTGVDWSTGNGDLGGQLPRVRVHHAEPLDLGYRPGRLDARVRSFGHEEEITERLAVL
                     AASAEPEARDVCFGRVRHAEALRFAGGAGREIRVDTVAVISTNFDDDAVSVDPDVDAVP
                     DIDLVVAEHERIWAERWRRHAEVEGDPAIVQGMRYSQFHLFGSIDRGRTVHNVPARGLS
                     SEYHSGHFFYNTEFFALPHAAWTDPAAAKAMLRFRVATLDAAREHARRTGYEGARFPEE
                     ADLLGESGSAHLVRDVLRDDEWEERAGAQVVHTSADVLHGLRSYVEITGDRDVLREECV
                     PLLVETARYLACLLRFDPEVGGRTVRGIMGFDEYHYDVDHDFGTNALVSWGLSWAAETL
                     RELAGHHSEVRAALRERGIGEDVLQEWAVAAREVYLPPARDGVRPLFAGYFELPDELCS
                     VEPGHNLPGPVKENDERRLSGLVKQADVVQTMVLLSERFTREEIERNLRYYEPRTAHGS
                     SLSPMTHAIAAAWAGDLPLATRLLAGTARYNLDFAPRDNFRNGIHLGAGAGAWLVLVRG
                     FLGADASGEVLRFAPRLPEGVTALRVPLRWRGRGLTVALTADGLELVADGDNPLTLPVE
                     VDGRRAELAPGGRRVFAPAPSGAVLTG"
     protocluster    10084..39979
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[20083:33372]"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20084..33372
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
     cand_cluster    10084..39979
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /kind="single"
                     /product="2dos"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             complement(11279..12217)
                     /NRPS_PKS="Domain: NAD_binding_4 (58-222). E-value:
                     7.2e-12. Score: 36.8. Matches aSDomain:
                     nrpspksdomains_ShinN01.8c_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MEY1"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q2MEY1"
                     /function="putative oxidoreduction in tobramycin/apramycin
                     biosynthesis"
                     /gene="aprD1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     255.3; E-value: 1.4e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.8c"
                     /note="possible translational coupling with ORF ShinN01.7c"
                     /product="putative tobramycin/apramycin biosynthetic
                     oxidoreductase"
                     /protein_id="CAI47643.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.3e-21, bitscore:
                     68.0, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIFVTGAAGYVGQAVLARLLAAGHDVTAVGHRTPVGWPAGTPSR
                     QADLTDAPAVLRALDGAEAVCHLAGLTRVRGSGVDVDRYYRVNVVGTLNVLDALVARHR
                     AGDGPARLVFLSSGAVYGRTGDAPVREDHPTLPTSAYGATKLAAEQAVGWYAGTGALSA
                     VSLRLFTAAGSVRPGCRPDDSTLVARALSVAAGENAVLPVNGDGSTVRDFVHVADVADA
                     VARAVEAPARRPAEVVNLGAVAASVREVVAAVERVTGRRVPVAHGPANSADQPWLAADT
                     GAARELLGWAPTRSSLERMIEDQWRVGGAGR"
     gene            complement(order(11279..12217,12221..12228))
                     /gene="aprD1"
                     /locus_tag="ShinN01.8c"
     gene            complement(11290..11295)
                     /gene="aprO"
                     /locus_tag="ShinN01.7c"
     regulatory      complement(11290..11295)
                     /gene="aprO"
                     /locus_tag="ShinN01.7c"
                     /regulatory_class="ribosome_binding_site"
     aSDomain        complement(11552..12043)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ShinN01.8c_NAD_binding_4.1"
                     /evalue="7.20E-12"
                     /label="ShinN01.8c_NAD_binding_4.1"
                     /locus_tag="ShinN01.8c"
                     /protein_end="222"
                     /protein_start="58"
                     /score="36.8"
                     /tool="antismash"
                     /translation="LDGAEAVCHLAGLTRVRGSGVDVDRYYRVNVVGTLNVLDALVARH
                     RAGDGPARLVFLSSGAVYGRTGDAPVREDHPTLPTSAYGATKLAAEQAVGWYAGTGALS
                     AVSLRLFTAAGSVRPGCRPDDSTLVARALSVAAGENAVLPVNGDGSTVRDFVHVADVAD
                     A"
     regulatory      complement(12221..12228)
                     /gene="aprD1"
                     /locus_tag="ShinN01.8c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(12233..13510)
                     /gene="aprF"
                     /locus_tag="ShinN01.9c"
     CDS             complement(12233..13510)
                     /codon_start=1
                     /db_xref="InterPro:IPR001646"
                     /db_xref="UniProtKB/TrEMBL:Q2MEY0"
                     /gene="aprF"
                     /gene_functions="other (smcogs) SMCOG1286:Pentapeptide
                     repeat protein (Score: 141.9; E-value: 3.4e-43)"
                     /gene_kind="other"
                     /locus_tag="ShinN01.9c"
                     /product="putative apramycin biosynthesis protein"
                     /protein_id="CAI47644.1"
                     /transl_table=11
                     /translation="MTAAATGVWGWAGELDGQPPDETLAEVAARAPASPAELLTTRLPP
                     GGLLVVTARHGRRRPDAGLLTRLTASGLTTEILRLAGAEMGSTDAFASTVDNDPHPDVL
                     VLDAPDLAAWGGRGVDGLVLRNLLERLRSRLPNTRLAIYVSDACFVVRHALPGTLLLTL
                     PRQDEDDPATGPLADRAEEVAAALGTGDARAVVEACDALARRPEFDPMSPARRLLDAVA
                     GHPDALREIVPELLARHWPAAPTTSPLEDGGVSPRATALLYRLLSLTEPDGPRSTLRRV
                     DVGRWLCALRADTYETLSAVTTVLRHEDLAGTNLSYAPSLEHCDLTGADLTEVDGYRVN
                     VSDGVLDNALMARSCFARGHLKRASLRGADLRDADLEYASFQQADLTGADLAGADLHRA
                     LLDQAVGLSVPVPAPVPAPAIEPTSA"
     gene            complement(13507..14403)
                     /gene="aprG"
                     /locus_tag="ShinN01.10c"
     CDS             complement(13507..14403)
                     /codon_start=1
                     /db_xref="GOA:Q2MEX9"
                     /db_xref="InterPro:IPR008928"
                     /db_xref="InterPro:IPR010905"
                     /db_xref="InterPro:IPR012341"
                     /db_xref="UniProtKB/TrEMBL:Q2MEX9"
                     /gene="aprG"
                     /locus_tag="ShinN01.10c"
                     /note="possible translational coupling with ORF ShinN01.9c"
                     /product="putative apramycin biosynthesis protein"
                     /protein_id="CAI47645.1"
                     /transl_table=11
                     /translation="MWALHTAGHTQAASAVADYVTSLLQADGDIPQPREEEYFLDVHYL
                     YANGYLTIGAHVLGRFGLSSKLMSFVETMQNPVTGGFRSHGPAVPGDGRCDSVSTSISG
                     LAALYTGRLSVARSAADFLGSLWAGQPDRENLFHAVADAQGNVLTSDDAVTISVRKAEG
                     DWYFIGLPALFLTALHEATEDQKYLDLATELMTYMDETCDDDAFIDSSCGKAGVAAAML
                     YRLTGKPRYREIAQQIGDLLCERQTPYGYWSEEETDDVADLFWGDLDMTAEYVMWLDLI
                     ARNLASGERVWAGAGAR"
     gene            15344..16420
                     /gene="aprH"
                     /locus_tag="ShinN01.11"
     CDS             15344..16420
                     /codon_start=1
                     /db_xref="GOA:Q2MEX8"
                     /db_xref="UniProtKB/TrEMBL:Q2MEX8"
                     /function="putative glycosyltransfer in apramycin
                     biosynthesis"
                     /gene="aprH"
                     /locus_tag="ShinN01.11"
                     /product="putative glycosyltransferase"
                     /protein_id="CAI47646.1"
                     /transl_table=11
                     /translation="MRIDDVTRPGLAGGVVALRADASAEWGVGHVVRCLALAEEVLARG
                     GRPVLVADLGDVAWLAEEVRARGLAVRPPASDPAGFADQLHALGARATVIDSYRLGPEH
                     YTAARAVAPVVALYDRHSGPVPGDVLVDQVFGAEQDPPPPDADQATVLRGPRYALIRDL
                     VRRHRPATRPAAMPLAGRAPRVLLVLGGTDARGATGALTEILLASCPSLDLTVVGGGLD
                     GPAPATGAGQRLSVHRPSAELPRLMAEADLVISAAGTTLAELCCVGAAAAAVWVVDNQL
                     PVYRSALAAGCVHGLGSLAEVLADPGRAGAAVRALLESPERRTALAGAAWELVDGAGRG
                     RVVDALAARLADRRPATR"
     regulatory      16497..16502
                     /gene="aprI"
                     /locus_tag="ShinN01.12"
                     /regulatory_class="ribosome_binding_site"
     gene            16497..17296
                     /gene="aprI"
                     /locus_tag="ShinN01.12"
     CDS             16508..17296
                     /codon_start=1
                     /db_xref="GOA:Q2MEX7"
                     /db_xref="InterPro:IPR007848"
                     /db_xref="UniProtKB/TrEMBL:Q2MEX7"
                     /function="putative N-methylation in apramycin pathway"
                     /gene="aprI"
                     /locus_tag="ShinN01.12"
                     /product="putative N-methyltransferase"
                     /protein_id="CAI47647.1"
                     /transl_table=11
                     /translation="MPRIDESRLRDLLAAAAGVAPAELDGWPGRAGWLDRAAAMLTDYV
                     AGVPLGYVLGEIHYLGRAFRSDRRALAVRRYSEPLVRRIVDDFAGEPVRAVEIGCGAAA
                     AICTLAKELTGEFVGTDVVPEALELAEENATRHRAPVRFVVSDLFDALDGRFDVIYANL
                     PRHHPSTPMPEARWEPSVALYDDSAEPFGLLRRFFAEVPDRLTERGRLYLEIPLDPAIA
                     DLLPGEPVVDGDGDDFARVITAADARRLPALVDRLTWPEG"
     gene            complement(17405..18118)
                     /gene="aprJ"
                     /locus_tag="ShinN01.13c"
     CDS             complement(17405..18118)
                     /codon_start=1
                     /db_xref="GOA:Q2MEX6"
                     /db_xref="InterPro:IPR005834"
                     /db_xref="InterPro:IPR006402"
                     /db_xref="UniProtKB/TrEMBL:Q2MEX6"
                     /function="putative phosphosugar mutase in apramycin
                     pathway"
                     /gene="aprJ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115:HAD-superfamily hydrolase, subfamily IA, variant
                     (Score: 128.1; E-value: 6.1e-39)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.13c"
                     /product="putative phosphosugar mutase"
                     /protein_id="CAI47648.1"
                     /transl_table=11
                     /translation="MRDTENAALVVLDIDGTLLDTPHLPAWRRGLARVLRDHAPERSAE
                     ITVERYHRHIAGRPRQVGARAALELAGLAPPPALVDELAAVKQQVFLEQAEETVLFPDA
                     GDFLDAAALAGTPLAFCTASRNAGELLAKRLPRLDGGDWLLDRLHHSLGPHGHYGDVPR
                     PEALRRVAAAWGAAPDGCVLVDDALSGVLAGQQVGMTAVLVDRFGLGVAAPGCPTVSTL
                     AELVPVSTGVRFPAE"
     gene            complement(18122..18613)
                     /gene="aprK"
                     /locus_tag="ShinN01.14c"
     CDS             complement(18122..18613)
                     /codon_start=1
                     /db_xref="GOA:Q2MEX5"
                     /db_xref="InterPro:IPR004820"
                     /db_xref="InterPro:IPR004821"
                     /db_xref="InterPro:IPR014729"
                     /db_xref="UniProtKB/TrEMBL:Q2MEX5"
                     /gene="aprK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.14c"
                     /product="putative NDP-octose synthase"
                     /protein_id="CAI47649.1"
                     /sec_met_domain="CTP_transf_like (E-value: 5.6e-16,
                     bitscore: 50.1, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTSTKVLTMPAAQDLREQLARQKITLGVCHGCFDILHSGHVHHL
                     TQAAGHTDRLLVSVTAARRINKGPNRPVFDDEARLTVLAALEVVDYVLLNDDDTAVPLI
                     RALRPDYYFKGADYANMRDPRVVEEVDAVSAVGGSFVLTDDAVFDSSTRAAGLLLDSGR
                     "
     gene            complement(18124..18130)
                     /gene="aprJ"
                     /locus_tag="ShinN01.13c"
     regulatory      complement(18124..18130)
                     /gene="aprJ"
                     /locus_tag="ShinN01.13c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(18671..20080)
                     /gene="aprM"
                     /locus_tag="ShinN01.15c"
     CDS             complement(18671..20080)
                     /codon_start=1
                     /db_xref="GOA:Q2MEX4"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q2MEX4"
                     /function="putative paromamine synthesis"
                     /gene="aprM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 247.6;
                     E-value: 4e-75)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.15c"
                     /note="conserved in other aminoglycoside gene clusters"
                     /product="putative glycosyltransferase"
                     /protein_id="CAI47650.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3.2e-33,
                     bitscore: 105.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLRVLRLTPFFHHDCVDRWPAEFDAVGGMQVQILRLSRQLARRG
                     VRQEVLTVGFPGLPRVREDSPGLVVRITRAPMPRLRSELTGLVGLNLAWFLGAMAECAR
                     RRRSRRPDLIQVHADGQLWALLAGPIASALLRRPYSLVLHCSRLGVYQPMSRYDQWQHR
                     FVAAVERWALRRADGVCALTARTADVVRAALRPHAVRVDVVPDSVDPEPPVDAGVPVAE
                     RLRAAGLPADAKVVGYVGRVAHEKGWAHFVELAARLAADPPAEPVVFLVVGDGPQRPRM
                     EERVAAAGLSDRFVFTGFLPNHEVPLTMSGIDVLVMPSVHEELGGSAIEAMVLGVPVVA
                     YGVGGLRDTVGTVAPELLVPPQDVPALVRAVRDVLARGAEHRARVRAGRPWLEENFGDG
                     VGVDRTVAHYRRVLAGRGGGGDLGPGVPGPGVPNPGALNPGVPGPGGAAPADPPDGGAS
                     AAGQRPPGSGP"
     CDS             complement(20084..21244)
                     /codon_start=1
                     /db_xref="GOA:Q2MEX3"
                     /db_xref="InterPro:IPR002658"
                     /db_xref="InterPro:IPR016303"
                     /db_xref="UniProtKB/TrEMBL:Q2MEX3"
                     /function="putative synthesis of 2-deoxy-scyllo-inosose"
                     /gene="aprC"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DOIS"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183:3-dehydroquinate synthase (Score: 368.3; E-value:
                     5.8e-112)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ShinN01.16c"
                     /note="conserved in other aminoglycoside gene clusters"
                     /product="putative 2-deoxy-scyllo-inosose synthase"
                     /protein_id="CAI47651.1"
                     /sec_met_domain="DOIS (E-value: 1.3e-173, bitscore: 567.8,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.7e-71, bitscore:
                     231.4, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVTTVAMGDVRFPYRLGTACVDQIVDRLAELEASRYLVVADPTV
                     AGLYGTDLVERVRRTAGPAELLVHEGGEENKGLGTLAELVETALRLGADRRSIVVALGG
                     GITGNIAGLMAALMFRGIRLVHVPTTIVAMLDSVLSLKQAVNSSVGKNLVGTFYQPVEV
                     LADTAFLRTLSTRDIRSGLCEVVKNALAIRPSMIDRLAAHLPLDQRYDDDVMRWIIDES
                     IAAKAQVTEADVHERKQGLVLEYGHTVGHALEHAAKGEVSHGAAVGLGMLAEAEIARRL
                     GLAGEDLIELHRDLISRMGIDLAFPAHVSPADVQLRLRYDNKRGYLSGAGDDGYVMVLL
                     KAPGVPLQSEGLPLTVADRAVVDAVVSEFAHPASAAAIGRRTRPEG"
     gene            complement(order(20084..21244,21250..21256))
                     /gene="aprC"
                     /locus_tag="ShinN01.16c"
     gene            complement(20087..20092)
                     /gene="aprM"
                     /locus_tag="ShinN01.15c"
     regulatory      complement(20087..20092)
                     /gene="aprM"
                     /locus_tag="ShinN01.15c"
                     /regulatory_class="ribosome_binding_site"
     regulatory      complement(21250..21256)
                     /gene="aprC"
                     /locus_tag="ShinN01.16c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(21278..22552)
                     /gene="aprS"
                     /locus_tag="ShinN01.17c"
     CDS             complement(21278..22552)
                     /codon_start=1
                     /db_xref="GOA:Q2MEX2"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/TrEMBL:Q2MEX2"
                     /function="putative L-glutamine:scyllo-inosose
                     aminotransfer in apramycin biosynthesis"
                     /gene="aprS"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     398.3; E-value: 5.9e-121)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ShinN01.17c"
                     /note="conserved in other aminoglycoside gene clusters"
                     /product="putative ketocyclitol aminotransferase"
                     /protein_id="CAI47652.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.4e-111,
                     bitscore: 364.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAQLAINQGTPVRTREWPLWPRPAKGTAEALSQVLASARWSLSG
                     PYRGVESFERRFARDFAHYVGAAHCVPAASGTASLMLAMEACGVGAGDEVIVPGLSWVA
                     SASTVVGVNAVPVFADIDPDTWCVDPAAVEAAITPATRAVAVVHLYSAVADLAALREIA
                     DRHGLALIEDCAQAHGAVYRGRRVGTHGRAGTFSMQHSKVLTSGEGGAVVTDDAELARR
                     VEHLRADGRCYPAAAPSAGAMELVETGELMGNNRCLSEFHAAVLVEQLKELDELNARRA
                     RNAAVLDGLLTELGCRPQQTSPGTDSRTYYVYGARLPEGELVGVDIARVTAALTAELGF
                     SVVPSYRPLPVNKLYDPTSRRRYAIGEDYEKRIDASRFQLPVCEGLAQRAFTLHHAALL
                     GDEADMHDIAAAVRKVLANSAELAA"
     CDS             complement(22658..23674)
                     /NRPS_PKS="Domain: PKS_ER (18-254). E-value: 2e-08. Score:
                     25.6. Matches aSDomain:
                     nrpspksdomains_ShinN01.18c_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MEX1"
                     /db_xref="InterPro:IPR002085"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q2MEX1"
                     /gene="aprE"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_zinc_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADSI-DH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 330.4; E-value:
                     1.8e-100)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ShinN01.18c"
                     /note="conserved in other aminoglycoside gene clusters"
                     /product="putative 3-amino-2,3-dideoxy-scyllo-inositol 1
                     dehydrogenase"
                     /protein_id="CAI47653.1"
                     /sec_met_domain="ADSI-DH (E-value: 5.1e-177, bitscore:
                     578.7, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 8.9e-28, bitscore: 87.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.3e-20, bitscore:
                     64.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVFDAPERALLRDKDVPEPARGEALVKIAYNSLCGSDLSLYR
                     GVWHGFTYPVVPGHEWSGTVVEVNGADESLRGAKVTGDLTVSCSRCAPCERGTPVLCDN
                     LQELGFNRDGACAEYMTIPVHNVYRLPDALDLKAACQVEPLAVALHAVANAGIGEGDKV
                     AVLGAGGIGLLLMQAAALRGATVTTVSEPVTERRERARELGARTVTSAAPGELAALVES
                     RPELVPDVVLEASGYPVAVQEAIEVVRPGGRIGLVGYRVEETGVMAPHHATVKALSIRG
                     SLGPGGRFAEAIEVLASGAINTDALLSHEFGLDDYADALDLALRRTNGNTRSYFNLG"
     gene            complement(22658..23686)
                     /gene="aprE"
                     /locus_tag="ShinN01.18c"
     aSDomain        complement(22913..23620)
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ShinN01.18c_PKS_ER.1"
                     /evalue="2.00E-08"
                     /label="ShinN01.18c_PKS_ER.1"
                     /locus_tag="ShinN01.18c"
                     /protein_end="254"
                     /protein_start="18"
                     /score="25.6"
                     /tool="antismash"
                     /translation="VPEPARGEALVKIAYNSLCGSDLSLYRGVWHGFTYPVVPGHEWSG
                     TVVEVNGADESLRGAKVTGDLTVSCSRCAPCERGTPVLCDNLQELGFNRDGACAEYMTI
                     PVHNVYRLPDALDLKAACQVEPLAVALHAVANAGIGEGDKVAVLGAGGIGLLLMQAAAL
                     RGATVTTVSEPVTERRERARELGARTVTSAAPGELAALVESRPELVPDVVLEASGYPVA
                     VQEAIEVVRPGGRI"
     regulatory      complement(23680..23686)
                     /gene="aprE"
                     /locus_tag="ShinN01.18c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(23779..24597)
                     /gene="aprP"
                     /locus_tag="ShinN01.19c"
     CDS             complement(23779..24597)
                     /codon_start=1
                     /db_xref="GOA:Q2MEX0"
                     /db_xref="InterPro:IPR003785"
                     /db_xref="UniProtKB/TrEMBL:Q2MEX0"
                     /function="putative amidohydrolization in apramycin
                     pathway"
                     /gene="aprP"
                     /locus_tag="ShinN01.19c"
                     /product="putative amidohydrolase"
                     /protein_id="CAI47654.1"
                     /transl_table=11
                     /translation="MTTADSAATSATTAPADEVRYDRLLPREFEARLAAAPVAYVPVGS
                     LEWHSAHMPYGVDTDKATAICERAARRHGGIVLPGSPWGFMQGNWRGATHPGLRVETIF
                     QLYTDILRGLSTVGFRAAVVVSGHWTTKQTIPIACALERVRNETGLRGMVTFDGSDDDC
                     GFDPELHLDMDHAGALETSVYGALFPENVHLERLDELDLSDLPGRECHLTRSGIQGRDP
                     REHADFERGRWHVDQVVDLLGAEARRLLAEAEAAPAEAVPGAESAPPAGG"
     CDS             complement(24594..25556)
                     /NRPS_PKS="Domain: NAD_binding_4 (2-122). E-value: 8.5e-13.
                     Score: 39.8. Matches aSDomain:
                     nrpspksdomains_ShinN01.20c_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MEW9"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="InterPro:IPR020025"
                     /db_xref="UniProtKB/TrEMBL:Q2MEW9"
                     /function="putative epimerization or dehydration in
                     apramycin pathway"
                     /gene="aprD2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     118.3; E-value: 7.7e-36)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.20c"
                     /note="possible translational coupling with ORF
                     ShinN01.19c"
                     /product="putative tobramycin/apramycin oxidoreductase"
                     /protein_id="CAI47655.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 9e-97, bitscore:
                     314.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.1e-15, bitscore:
                     46.0, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMITGGTGSLGRAFIRNALDTLGCDSVVVYSRDELKQRELREAFD
                     HDRRLEWVIGDVRDPDRLRHAMRDVEHVVHAAALKQVDTAERNCIEYIRTNVLGAQNVI
                     DAAVETGVSRVVALSTDKASSPVNLYGATKLCADKLFVAASEYAGRRGTRFGVVRYGNV
                     LGSRGSVIPLFKQLAAAGKPITITDKRMTRFWLSIEAAVRFIVESFDQMSGGEIFVPRI
                     PSMRVIDLAEAIAPRSPIHEVGIRPGEKLHEEMISESDARRTVRLGDRYVVRSSLAEEA
                     DVPAGGTPVPDGFSYTSDKNDEWLSVADLRAEYAGAVSA"
     gene            complement(order(24594..25556,25561..25565))
                     /gene="aprD2"
                     /locus_tag="ShinN01.20c"
     aSDomain        complement(25191..25550)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ShinN01.20c_NAD_binding_4.1"
                     /evalue="8.50E-13"
                     /label="ShinN01.20c_NAD_binding_4.1"
                     /locus_tag="ShinN01.20c"
                     /protein_end="122"
                     /protein_start="2"
                     /score="39.8"
                     /tool="antismash"
                     /translation="ITGGTGSLGRAFIRNALDTLGCDSVVVYSRDELKQRELREAFDHD
                     RRLEWVIGDVRDPDRLRHAMRDVEHVVHAAALKQVDTAERNCIEYIRTNVLGAQNVIDA
                     AVETGVSRVVALSTDK"
     CDS_motif       complement(25509..25550)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ShinN01.20c_0001"
                     /evalue="4.10E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ShinN01.20c"
                     /protein_end="16"
                     /protein_start="2"
                     /score="13.0"
                     /tool="antismash"
                     /translation="ITGGTGSLGRAFIR"
     regulatory      complement(25561..25565)
                     /gene="aprD2"
                     /locus_tag="ShinN01.20c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(25814..26560)
                     /gene="aprD3"
                     /locus_tag="ShinN01.21c"
     CDS             complement(25814..26560)
                     /NRPS_PKS="Domain: PKS_KR (8-97). E-value: 3.4e-10. Score:
                     31.9. Matches aSDomain:
                     nrpspksdomains_ShinN01.21c_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MEW8"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q2MEW8"
                     /gene="aprD3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     173.6; E-value: 8.6e-53)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.21c"
                     /product="putative tobramycin/apramycin oxidoreductase 3"
                     /protein_id="CAI47656.1"
                     /transl_table=11
                     /translation="MTAAGPRRVLVTGASRGLGLRAAEALADRGWSVVLGCRRVGDVGP
                     VLARARGRGAPVSAVALDVTDPGSVAAAVAAVAELGGPLHALVNNAGVFRHEEEEFQDL
                     RPGDALDLLLTNACGPLLVTRAFLPLLRAAGGAAVVNVTSRDADEDTFDGLFTGYRMAK
                     AALNAMTRNLAIALRPDRIVVNAVDPGWIPTDMGGPEAPDSLDAAVAAVAGAVELAGGD
                     RTGRLLRAQRPPGSPGRRRADGATRR"
     aSDomain        complement(26270..26536)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ShinN01.21c_PKS_KR.1"
                     /evalue="3.40E-10"
                     /label="ShinN01.21c_PKS_KR.1"
                     /locus_tag="ShinN01.21c"
                     /protein_end="97"
                     /protein_start="8"
                     /score="31.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VLVTGASRGLGLRAAEALADRGWSVVLGCRRVGDVGPVLARARGR
                     GAPVSAVALDVTDPGSVAAAVAAVAELGGPLHALVNNAGVFRHE"
     CDS_motif       complement(26414..26533)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ShinN01.21c_0001"
                     /evalue="3.90E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ShinN01.21c"
                     /protein_end="49"
                     /protein_start="9"
                     /score="16.3"
                     /tool="antismash"
                     /translation="LVTGASRGLGLRAAEALADRGWSVVLGCRRVGDVGPVLAR"
     regulatory      27752..27758
                     /gene="aprQ"
                     /locus_tag="ShinN01.22"
                     /regulatory_class="ribosome_binding_site"
     gene            27752..29278
                     /gene="aprQ"
                     /locus_tag="ShinN01.22"
     CDS             27767..29278
                     /codon_start=1
                     /db_xref="GOA:Q2MEW7"
                     /db_xref="InterPro:IPR000172"
                     /db_xref="InterPro:IPR007867"
                     /db_xref="UniProtKB/TrEMBL:Q2MEW7"
                     /gene="aprQ"
                     /locus_tag="ShinN01.22"
                     /product="putative hexosamine-6-dehydrogenase"
                     /protein_id="CAI47657.1"
                     /transl_table=11
                     /translation="MKFVTLQEAAGQVFDVCVVGSGASGAVTAFTLAGRGMSVLVVEQG
                     DVIPPGGKIDDHLDPDSWAYAWRHGRWWTTGYPWSAQAFGGGTVFYAGVSFRYHPRDFA
                     PSPEFLGAAAYEHWGLTRQDLDPYYDWIEDQLAVAGPSGATVAEYQFPRYKREKLSYTS
                     QGRVLAEAAARLGWRPVATPLAISGVADRFTRGCQQLTPCTDNACPVGAKADVASRLLS
                     RCDDNLSVLLRTRVARLVATRPGVVDSAEVLHADERDSGTIRARRFVLAANAIQSAALL
                     LRSASRLEPDGMGNSSGMVGQHLAMKNSVYLRTHVRREDDYRPLQHRYSSMTSLDSMYD
                     PEFPDGMGGLIYEANPWDNVKDNAFMPLQLECSVGDRPRARNQVRLSKDLDSYGLPRVV
                     MDYVAHKRDLARLRVLRGRASELLRSLGGRVRHVSTKYELGSAHLHGTLRSGRDPRSSV
                     TDPLGRLHDYDNVWAVDGAVFPFAGNLNPTLTIQANARRIASAIS"
     regulatory      29333..29339
                     /gene="aprD4"
                     /locus_tag="ShinN01.23"
                     /regulatory_class="ribosome_binding_site"
     gene            29333..30709
                     /gene="aprD4"
                     /locus_tag="ShinN01.23"
     CDS             29339..30709
                     /codon_start=1
                     /db_xref="GOA:Q2MEW6"
                     /db_xref="InterPro:IPR006638"
                     /db_xref="InterPro:IPR007197"
                     /db_xref="UniProtKB/TrEMBL:Q2MEW6"
                     /gene="aprD4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 295.9; E-value: 8.5e-90)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.23"
                     /product="putative Fe-S oxidoreductase 4"
                     /protein_id="CAI47658.1"
                     /sec_met_domain="PF04055 (E-value: 3.9e-17, bitscore: 54.1,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRMRLGKLLLVSPKTSFGRDLQRTYAGGLGTVCKDEDFLLPPLD
                     LMRLAGVLREDADEIAIADEEVTGVVAASPGSTVICHVSLPSLLEDAERMATFREQGAR
                     CYAYTSIRSPVQWRELFERAGCVGILLPESISFARAALAGDATVPGLVTPENLLEPRHH
                     QPRFGDLAAEPLPARDLVDHTPYMFPPISLNGITSINGSFGCPYPCRFYCPYPLSEGRK
                     IRTYPVERIVAEFRQCAELGITAAVFRDPVFSFHRDRTIEMCRAIEAAGTGVPWWCETR
                     IDRLDEEVVAALVAAGCVGVEVGVESGDPEMQATAVRKRLDLDTVRRFHAVARKAGLKL
                     VFLFLIGLPRETRMSIRRTFDFILELGLAHTEFNLSVITPYPGTELHQIAVDKGWIDGS
                     QDNFTSHNAVMHTDQLTIGDLEQASRFVDELHGVCKAGPAERAEFQARLHAWSTSDA"
     misc_feature    29363..29365
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     regulatory      30718..30725
                     /gene="aprZ"
                     /locus_tag="ShinN01.24"
                     /regulatory_class="ribosome_binding_site"
     gene            30718..32134
                     /gene="aprZ"
                     /locus_tag="ShinN01.24"
     CDS             30734..32134
                     /codon_start=1
                     /db_xref="GOA:Q2MEW5"
                     /db_xref="InterPro:IPR001952"
                     /db_xref="InterPro:IPR017849"
                     /db_xref="InterPro:IPR017850"
                     /db_xref="InterPro:IPR018299"
                     /db_xref="UniProtKB/TrEMBL:Q2MEW5"
                     /gene="aprZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) strK2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.24"
                     /product="putative 6-phosphate phosphatase"
                     /protein_id="CAI47659.1"
                     /sec_met_domain="strK2 (E-value: 0.0, bitscore: 1027.2,
                     seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPHPQKRRSRTSALLAVAALAAALSPTIPAVADDTAEGFALAPN
                     ADRTHHVRSAVRGGKARNVLLFVGDGMGDSEITLARNYELGAAGRLNLDRLPLTGAYTT
                     YSVAKGDPGRVEYVTDSAAAATGYAIGAKTYNGAVGVDAHGRERPTILELAKRRGYRTG
                     NVTTAELQDATPAALSAHVLDRTCRGPQDMKECAPNDKRNGGAGSIAEQQVALRADVLM
                     GGGGKYFDQQVAAGQFAGRTVRQQAVDSGFQVITSADQMRALDRERPVLGVFAAEGLDS
                     TWTGPPAKAGGTPPSRCAENPARRKDQPTLADMTRASIDLLERRSRGHDRGFFLQVEGA
                     QIDWGAHDGLPCEQIGETVQFDRAVAVGMEFARRRPDTLVIVTADHAQTTQIIPNGQKS
                     PGMTATLITNEGGHMTVNYATGLPGELQEHTGTQVRIAGYGPQAANVVGVTDQTDLFRT
                     LSRAMGVR"
     regulatory      32239..32244
                     /gene="aprL"
                     /locus_tag="ShinN01.25"
                     /regulatory_class="ribosome_binding_site"
     gene            32239..33372
                     /gene="aprL"
                     /locus_tag="ShinN01.25"
     CDS             32251..33372
                     /NRPS_PKS="Domain: Beta_elim_lyase (37-203). E-value:
                     9.4e-10. Score: 30.0. Matches aSDomain:
                     nrpspksdomains_ShinN01.25_Beta_elim_lyase.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MEW4"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/TrEMBL:Q2MEW4"
                     /gene="aprL"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     321.1; E-value: 1.7e-97)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ShinN01.25"
                     /product="putative aminotransferase"
                     /protein_id="CAI47660.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.1e-100,
                     bitscore: 326.5, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSHVSFAHVDTENAALVDEFLPVLKERLAGGVFIGGEEVDRLER
                     RIARLHQVEHAVAVNSGTDALRLTFRALGIPRGTTGITVANTFVATVGALLSEGINPLL
                     VDVGADENVDVAALEEAITPDTSVVVAVHLRGLPAEIAAVREICARRGVHLVEDCAQAV
                     LASAGGVPVGAFGVAGCFSLHPLKNLGACGDAGVVVTNDDALAAELRLLRNHGLRDRDT
                     VVRWGENSRLDALQASLLNVKLDHLEEWTRRRRDLAARYDELLADLPLVLPPRPEDRVH
                     VYHRYSVMTEHRDALRAHLADAGVQTAVHYPIPIHRQPAARGGQLRIAGRGLAVTERQA
                     GQILSLPLHPLMPERDLRATAREVRAFFESRPR"
     aSDomain        32362..32859
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ShinN01.25_Beta_elim_lyase.1"
                     /evalue="9.40E-10"
                     /label="ShinN01.25_Beta_elim_lyase.1"
                     /locus_tag="ShinN01.25"
                     /protein_end="203"
                     /protein_start="37"
                     /score="30.0"
                     /tool="antismash"
                     /translation="EEVDRLERRIARLHQVEHAVAVNSGTDALRLTFRALGIPRGTTGI
                     TVANTFVATVGALLSEGINPLLVDVGADENVDVAALEEAITPDTSVVVAVHLRGLPAEI
                     AAVREICARRGVHLVEDCAQAVLASAGGVPVGAFGVAGCFSLHPLKNLGACGDAGVVVT
                     NDD"
     regulatory      33410..33414
                     /gene="aprD5"
                     /locus_tag="ShinN01.26"
                     /regulatory_class="ribosome_binding_site"
     gene            33410..34462
                     /gene="aprD5"
                     /locus_tag="ShinN01.26"
     CDS             33425..34462
                     /NRPS_PKS="Domain: NAD_binding_4 (11-186). E-value:
                     2.2e-11. Score: 35.2. Matches aSDomain:
                     nrpspksdomains_ShinN01.26_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MEW3"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q2MEW3"
                     /gene="aprD5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     237.5; E-value: 3.8e-72)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.26"
                     /product="putative epimerase/dehydratase"
                     /protein_id="CAI47661.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.7e-12,
                     bitscore: 36.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.1e-16, bitscore:
                     51.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKHAGPGLVLITGGAGYIGSVLTRRLLDKRVRVRVLDSRIFGDG
                     LRDLADPGLENVQGDIRDADLFRTALRDVDVVVHLAAVANDPSFDLNPELGRSVNFECL
                     DHVMRLSKEAGVRRFVYASSASVYGISDSPEVDESHPLVPITDYNRYKALGEEILFPLT
                     DTSFETVALRAATVCGVSTRQRLDLTVNLLTAQAVGNREITVFGGAQYRPNVHIDDLVE
                     VYQRLVLDDSLGALNGAPINVGNENLPVADIAKVIATRVTAKLGAEVTTTTTPTDDRRS
                     YRLTSRRLHQLLGITPTRTVADASDDVTDAILDGRLPNPLTEARYYNVRWMKDPRSQDL
                     LTYTP"
     CDS_motif       33455..33523
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ShinN01.26_0001"
                     /evalue="6.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ShinN01.26"
                     /protein_end="33"
                     /protein_start="10"
                     /score="12.3"
                     /tool="antismash"
                     /translation="LITGGAGYIGSVLTRRLLDKRVR"
     aSDomain        33458..33982
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ShinN01.26_NAD_binding_4.1"
                     /evalue="2.20E-11"
                     /label="ShinN01.26_NAD_binding_4.1"
                     /locus_tag="ShinN01.26"
                     /protein_end="186"
                     /protein_start="11"
                     /score="35.2"
                     /tool="antismash"
                     /translation="ITGGAGYIGSVLTRRLLDKRVRVRVLDSRIFGDGLRDLADPGLEN
                     VQGDIRDADLFRTALRDVDVVVHLAAVANDPSFDLNPELGRSVNFECLDHVMRLSKEAG
                     VRRFVYASSASVYGISDSPEVDESHPLVPITDYNRYKALGEEILFPLTDTSFETVALRA
                     ATVCGVSTRQRL"
     gene            35325..36674
                     /gene="N01.27"
                     /locus_tag="ShinN01.27"
     CDS             35325..36674
                     /NRPS_PKS="Domain: AMP-binding (67-342). E-value: 2.5e-21.
                     Score: 67.5. Matches aSDomain:
                     nrpspksdomains_ShinN01.27_AMP-binding.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MEW2"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="UniProtKB/TrEMBL:Q2MEW2"
                     /gene="N01.27"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score: 77.5;
                     E-value: 1.2e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ShinN01.27"
                     /note="outside the apramycin gene cluster"
                     /product="putative phenylacetyl-CoA ligase"
                     /protein_id="CAI47662.1"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-27, bitscore:
                     85.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVERSVVPHLVDPDAEGANPERRRELQQHRLRGLVDRLLAADGV
                     QAERLRAAGVRQGADVTLRDLPRLPTLSKPDLWEHYPFGLRLAPETDIVCVHGSSGTGG
                     RPTLIPYTAHDLEVWAQVMARALGGAGATRTSVVHCAYGYGLFTGGLGIHHGAIRLGAT
                     VVPMSGGMTDRQLRLLLDLRADVLCCTPSYAVHLGEALRAAGIEPDELALRTGVFGAEP
                     WTDGMRAQIEQSLGLRALDIYGLSEVIGPGVACESLDSDGMLNVAEDHFYVEAVDDEGR
                     PVPDGAPGELVFTTLTKTGMPLLRYRTGDIARLAGPAPGSPRTLRRMSKLLGRRDDMLV
                     VRGVNVFPSEIEAVLLADERVAPHYLVVEDRRDPARPELRIAVEPFAESVAVDEAETLR
                     HDLVGALRARLGIGCAVTVLPPGGVPRSETGKARRLARWTGGEPPVRGLG"
     aSDomain        35526..36350
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ShinN01.27_AMP-binding.1"
                     /evalue="2.50E-21"
                     /label="ShinN01.27_AMP-binding.1"
                     /locus_tag="ShinN01.27"
                     /protein_end="342"
                     /protein_start="67"
                     /score="67.5"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="RLPTLSKPDLWEHYPFGLRLAPETDIVCVHGSSGTGGRPTLIPYT
                     AHDLEVWAQVMARALGGAGATRTSVVHCAYGYGLFTGGLGIHHGAIRLGATVVPMSGGM
                     TDRQLRLLLDLRADVLCCTPSYAVHLGEALRAAGIEPDELALRTGVFGAEPWTDGMRAQ
                     IEQSLGLRALDIYGLSEVIGPGVACESLDSDGMLNVAEDHFYVEAVDDEGRPVPDGAPG
                     ELVFTTLTKTGMPLLRYRTGDIARLAGPAPGSPRTLRRMSKLLGRRDDMLVVR"
     CDS_motif       36318..36380
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ShinN01.27_0001"
                     /evalue="5.80E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="ShinN01.27"
                     /protein_end="352"
                     /protein_start="331"
                     /score="15.8"
                     /tool="antismash"
                     /translation="LGRRDDMLVVRGVNVFPSEIE"
     CDS             complement(36760..37563)
                     /codon_start=1
                     /db_xref="GOA:Q2MEW1"
                     /db_xref="InterPro:IPR001853"
                     /db_xref="InterPro:IPR012335"
                     /db_xref="InterPro:IPR012336"
                     /db_xref="UniProtKB/TrEMBL:Q2MEW1"
                     /gene="N01.28c"
                     /locus_tag="ShinN01.28c"
                     /note="outside the apramycin gene cluster"
                     /product="putative membrane protein"
                     /protein_id="CAI47663.1"
                     /transl_table=11
                     /translation="MGGAERTARKRKQTTQAARAVAAARGGNDRRNVIIGVVIVVVMAV
                     AVIGGVLYTRNSSTSGGAGDIPVTAAHAQYPTKVEDDGTVLAGNESAKVTVDVYEDFLC
                     PACGSFEKLYGEQLEKAVADGKVKARYHILNLLDRYSNPAGYSLEAANAAIAAAGTGKF
                     PDFHASLFRTQPKEGGKGYTQDQLVKLGQAVGISGGDFESAVRGGKYNEQIKKQLEAAG
                     NNPALQRESAQGKSFGTPTIAVNGTMVDLQDAEWLKKAIEQSGQG"
     gene            complement(order(36760..37563,37572..37579))
                     /gene="N01.28c"
                     /locus_tag="ShinN01.28c"
     regulatory      complement(37572..37579)
                     /gene="N01.28c"
                     /locus_tag="ShinN01.28c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(37578..38120)
                     /gene="N01.29c"
                     /locus_tag="ShinN01.29c"
     CDS             complement(37578..38120)
                     /codon_start=1
                     /db_xref="GOA:Q2MEW0"
                     /db_xref="InterPro:IPR009908"
                     /db_xref="UniProtKB/TrEMBL:Q2MEW0"
                     /gene="N01.29c"
                     /locus_tag="ShinN01.29c"
                     /note="outside the apramycin gene cluster"
                     /product="putative membrane protein"
                     /protein_id="CAI47664.1"
                     /transl_table=11
                     /translation="MAVGMPARRSVGDLLGTLVRFGLAAVWLVSGAIKAAAPERTYLSV
                     QAFRVLPDALAGPVAAVLPFVELGLGVLVLFGVGTRVVAALSCLVLLAFVAGITQAWAR
                     GLSIDCGCFGGGGDVAPGETRYPEELARDTGFLALAVWLLVRPRSLLSVDGWLGLGRPA
                     RDGDDGDDRDEPVPAES"
     gene            38333..39052
                     /gene="N01.30"
                     /locus_tag="ShinN01.30"
     CDS             38333..39052
                     /codon_start=1
                     /db_xref="InterPro:IPR008217"
                     /db_xref="UniProtKB/TrEMBL:Q2MEV9"
                     /gene="N01.30"
                     /locus_tag="ShinN01.30"
                     /note="outside the apramycin gene cluster"
                     /product="putative membrane protein"
                     /protein_id="CAI47665.1"
                     /transl_table=11
                     /translation="MAQTEKVGHGEIGHIHSDVSGGWLRPAVFGAMDGLVTNIALVAGV
                     GGGGAGPDVVVLSGVAGLVAGALSMAIGEYTSVETQNDAVRAEVAVERAELRDNPEGER
                     AELVEAYVAMGLTRPTAERVAAEVHANPELAVRVHVTQELGVNPDEQPSPWTAALLSFL
                     CFSLGALTPLAPFLLGFASLPAGLLVGGAGLFVAGALVARWTTRSWWRNGLRQLALGAL
                     AAVATFLVGSVVGVVTT"
     regulatory      39270..39277
                     /gene="N01.31"
                     /locus_tag="ShinN01.31"
                     /regulatory_class="ribosome_binding_site"
     gene            39270..>39979
                     /gene="N01.31"
                     /locus_tag="ShinN01.31"
     CDS             39281..>39979
                     /codon_start=1
                     /db_xref="GOA:Q2MEV8"
                     /db_xref="InterPro:IPR004236"
                     /db_xref="UniProtKB/TrEMBL:Q2MEV8"
                     /gene="N01.31"
                     /locus_tag="ShinN01.31"
                     /note="outside the apramycin gene cluster"
                     /product="putative glutamyl endopeptidase precursor"
                     /protein_id="CAI47666.1"
                     /transl_table=11
                     /translation="MSARTRLRGRTLGVAATLAALAAVALTGAAGSAVAAPAEQLSGGQ
                     LAAVDYLSGRGLDRAEAVRRVLAQEGQTRTATQLADKLGARVAGSYVDQGSGALVVNVT
                     DDGAADEVRRSGATAKKVDRGVTDLNAAKARLDQAGKAARGASWYVDVPNNQVVVQAPA
                     GDSSAGVTDLLRTAEALGGTARVERVQGKATTQATNLYGGQQIEFSVNGSGYVCSDGFN
                     ATDRSGRAVMI"
ORIGIN
        1 gatctcgtgg tgtgccgagt acgggatgtc ctcgtagtag agcgtgctga attcgtggtc
       61 cacccggcgg agggcctcgt gcaccatgag gtggtcgatg tggtcgccca ttccggccgg
      121 cgccaggacg aggtcggggg ccgcggcccg gaccgcctcc gccaggacgt cgaccacctc
      181 gtcggtgagc gggtcgtcgg ccaccctggc cgtcagctcc ccctcgtcgt cgtagccccg
      241 gaggctggcg tcggggaagt ccagcagggt gtacgcgatg ccgtgggcgt cgcagtaccg
      301 gcggtcctcc tcggcgcgga cccgggacac ggcctcctgc ccctcggcgg ccagccgcgg
      361 ggacaccgtc cactctgacc gcccgaacac ggtcagcagc gtggccgtgg cctcccccag
      421 gtgggcggcc accactccgc cgcaggagta ggcgatgtcg tccgggtgcg gggacacgag
      481 taacaggttt ccggcgaagg cgaagttctc tggcacgtca ctctcccgcg tcgacaggcg
      541 gacaaccagg tggagaaccg ggcggacaac gaggtggacg acagggcgga caacggggac
      601 ggcgaacggg gaaggagaac ggacgccggc gtcaggcgct cgcgctcgtg ctggccagcc
      661 acgcctggtg cagcgtggcg aacttgccgc cgctctccac gagctgggcc gggggaccgt
      721 cctccacgat ccggccgtgc tcgaccacga gcacccggtc cgcggcgagc acggtggaca
      781 accggtgggc gatgatcaac gcggtccggc cgcgcagcgt cgtgtgcaac gcgcgttgga
      841 cggcgcgctc ggtggcgatg tccatgctgg aggtcgcctc gtccaggatc agcacggccg
      901 agtcggccag cagcaccctg gccagggcca cgagctggcg ctgccccgcc gacagccggc
      961 cgccgcgctt gttgacgtcg gtgtcgtagc cgtcggggag ctgggtgatg aactcgtgcg
     1021 ccccgatcgc ggtcgccgcc cgcacgatct cctcccggct cgcgtccggc cgacccagcg
     1081 cgatgttctc ggcgaccgtg ccggagaaca ggaacgactc ctgcgtgatc atcgacgtgg
     1141 cggcgcggag gtcggcgtcg gcgacctccc gcaggtccac gccgttgatc gagacccgac
     1201 cgccggtcgg gtcgtagaac ctggccacga gcttcgcgat cgtggacttg ccggccccgg
     1261 tctcgcccac gatggcgacc gtctgccccg ccgggatgcg cagggtcacg tcccgcagca
     1321 ccaggtcctt gctcgactgg tagcggaagt cgacccggct gaagtcgatc gtcgcctcgc
     1381 gggcgtgcag cggcacgggc cgggccggct gggcgacggt cggctcctcc tccagcaccc
     1441 cggagatctt ctccagggcg gccgaggccg aggcgtagga gttggcgaac cgggcgaggt
     1501 cgtccaccgg gtcgtagaac ttgcgcaggt acagcacgta cgcggcgagg acgccgacct
     1561 ccaggtggcc gttgatgatc cgccaaccgc cgacgagcag caccagggcg acggtcgtgt
     1621 tgccgatcag gttgatcccg gcggtggagt gggccaggcc gtaaccggcc cggaccgtgg
     1681 cgtcctggtt cgcggcgttg agcgcgccca tcgtccgcga gttggtctcc tccagccggt
     1741 acgcctgcac cacgcggatg ccgttcatcg tctcgacgaa gtggctgatc acgcgggcga
     1801 tcgccgaccg ggtgcgccgg tagaagaagt gggagcgcgc ccggtacctg gcggtgatcc
     1861 acagcagcgg gacgaaggtc agcacgatga cgccggtcag cggcaggtcg agccagacca
     1921 gcagcaccgc gatggtcacc acggacagga acgcccggaa caggccctcg atgctctcct
     1981 ccagcagcgt gctcagcgcc tggaggtcgc tggtgagccg ggagatcacc ttgcccgagg
     2041 tgtaggactc gtggaaggac agcgacagcc gctggacctg gcggaacagc cggtgccgca
     2101 gttccagcag cacgctctgc ccgatccgac cggacagcgt catgaaggag taggtcaggc
     2161 cggcggaggc gacgctggag accaggtagc ccgccacgta ccaggtgagc gggccgtagt
     2221 cctgcctggc cgcggccggg atgccgctgt cgatcacggc ggcgatcagc agggggcggg
     2281 ccatctccgc cgccgtgtcc agcacggcca gcaggagggc gaccacggcg cccacccggt
     2341 gcgggcggag cacgtccagc agcagccggc gcgagcgccg ttgcagctgc cgcccgacgt
     2401 ggcggtccag cgtgtcgtgg tcctcggcgg ccacaccgcg ccactcctgg cgtgcgggct
     2461 cgccggcttc ggtctcctcg gcggcgctcg tccgcgtgtt gggctggttc atcgcctcgc
     2521 cgtcccggcc tcgggggtcc gctggtcgtc gggtgccatg agctcccggt agcgcgggca
     2581 gtcccgcaac aggtcctggt gggtcccgac ggcgtcgacg cggccgtcgg cgagcagggc
     2641 gacccggtcg gcgagctgca ccgtgctcgg ccggtgggcg acgaccagcg cggtgacgcc
     2701 ccgcagcacc tggcgcagcg ccgcctccac ctcggcctcg gtgtggatgt ccaacgcgga
     2761 cagcgggtcg tccatgacga gcagcgccgg gcgggcgacc acggccctgg ccagcgccag
     2821 ccgctgccgc tggccgccgg acagcgagaa gccctgctcg ccgatctcgg tgtccagccc
     2881 cagcggcatg gcggccacga aggactcggc gttggcgacc cgcagcgcct cgcgcacctc
     2941 gtcgtcggtg acgtcggtcc ggttgagccg cacgttgtcg cgcacggtgc cggagaacag
     3001 cacgggctcc tcgaagacgg tggcgacggc ggcgcgcagg tcggccagcg gcacccggcg
     3061 gatgtcggtg ccgtcgaggg tgatccggcc gccggtcacg tcgtagagcc ggctgaccat
     3121 gccgaccagg gtggacttgc cggagccggc gccgccgacc agcgcgagcg tctcgccggg
     3181 ccggatctcc aggtccaccc cgcgcagcag ctcctcgtcc gccccgtcgt agcggaaccg
     3241 gaccccctcc acgcgcagcg cgccccgcac cggcgtcgac agcgggaccg ggtcgacggg
     3301 gtcggtgacc gtgacctcgg cccggacgat ctggaagtac cgctcggtgg ccgccgccgc
     3361 gtcgttggcc tcggccagca ggtagccgat ggactccagc ggccactgca ggtaggcgac
     3421 gaccgcgacc gcggccacca gctcgccggc gctcatcgag cccctggcgg cgaggtagcc
     3481 gccgatcccc agcacggcgc ccagcgcgac ctccggcagg ccgacgatgg tcgcggtcag
     3541 catgccgagc atccgcacct tgctgatctc ggtcgcgcgc agcaactcgg cccgctgccg
     3601 gaacgcccgc accgcctggc cgctgcggcc gaacgccttg aggacccgga tgcccagcac
     3661 cgactcctcg atccgcgtcg tgaggtcgcc gagctggttc tgggcgcgca ggctgcactc
     3721 cttgtaccgc gcctcgaaca cgatcgaacc gaccgcgacc ggcaggctga tcaccgtgaa
     3781 ggccgcgccg agcagcggcg acatccagca gagcacgccg atgctgacca cgatcgtgaa
     3841 gctgttcacc accaggtaca ccagggcgta gcgcgggaac cgcacgatgg tggtgaggtc
     3901 ggcgacggcc cgggacagca gctggccgga gtgccaccgg tcgtggaagg ccagcggcag
     3961 gcgctgcagg tggtcgtaga gctgggcccg catccggctc tcgatccggg cgctgggccc
     4021 gacgacgagc cggtgccggc cgaggaagaa cgccgcctcc agcgcgccga gcaggaacgc
     4081 gccgccggtc gtccagagca ggcccgtcat gtcccgcgcc gccaccggcc cgtcgacgac
     4141 ccgttggatc accaacggga tcagcagccc gcagatcgtc gtcgccagtg ccgacagcag
     4201 cgcccagccg agcagcgcga actcggggcg gaagtagggt ttcaaccgcc acagcgtggc
     4261 gatcgcgctt tttcgcctga cactttccgg cggcgctgtc tgcaagctca tgcggaagcc
     4321 cggttcctcg tcgatcacgt cggcggcact gttcacgtcg gcggcaccgg accgaaaggc
     4381 gcgggaccga aaggggtcag atcggaaaaa ccggttgacc ggccgatctc gtcgttcccg
     4441 tcgttctcgt cgcgctccgc ggcgtcaccc cgccgcgacc gcgcggcgca agccattccc
     4501 cgttcggggc gacccgaaga aaggtgcgcc ggtcccgcct tcccacctgg cgtttatggg
     4561 ttgacgccgg tcatcgcgca ccatgacaac gccggcgccg atagggtatg catgaacgaa
     4621 gactacactt tccccgcaac ccggaggcgg gcgtgaaaga atctttcctg ctcagcggcg
     4681 tcggtctcgg cgattccacc ctcgtgcgct ctcttcgcag cggcggggag atgacgtggc
     4741 tcgttcgctc gaacagtgga ttgacacccg agctggtggt cgtgaagaga aaacgcgact
     4801 atctgagcga gagcgagttc ctggcgcact gcgccgtgca ccgccgactc gccgacgccg
     4861 gcggccccgt tcccggcctg cccgcgtcgg cgccggacaa ccccgtccgc ggtccggacg
     4921 gcgccctgta cgagatctgg gagtgggtcg aggggcgtcc ggtcgacgtc gccagcccgg
     4981 ccgacctggc ggccctcggg gccgcgctgg ccgagttcca cctcctcgcc gacggcgcgc
     5041 tcgacggggt cgacctggac cccaaggagc cgcacgaccg gttcgagaag gcccgcttcc
     5101 acttcccgct gctggccgag ggtctgggcg acgcgggcgc cgagcagcac cgcgcgctgg
     5161 tggcggcgtg gaccgcggcg cacgagcggg cgcgccggga gaccccgctg ccggccaacg
     5221 tgctgcacgg cgacccgtgc ccggagaacg tcctcgtcac cggccccggc cgggcggtgc
     5281 tgctcgacct ggacgacgtc caccccggcc ccgcggtgtc ggacctcgcc tggtcgctca
     5341 cccgggtggg cgcggtggtc cccgagggcg acggcttccg cgaccggtgg cacgccgagg
     5401 ccgtcgcggc ggtgctcgac ggctaccgga gccgccgtcc gctgagcgcg gcggaacgcg
     5461 cggcgctgcc gcactggatc gtggcgagcc tgtgctgcgc ggcgtccgac cagctctacg
     5521 actacgggtg gaagatcgac acggcggcgc tgcccgccga gtgcgaccgg gtgctcgccc
     5581 tggccgaacc gggcggggcg cccctgcccg acgcctgagc gagcaaggcg tgagcccgcg
     5641 gggtgcccag agagggggcg aaagggtgtt cggggtccgc ttgtgacaac cgacctgaac
     5701 acccttcccg ccgcgcccca catcacgatc gacgtccacc agcgggctgg tccgtgtcgg
     5761 cggatcaccg tgagctgacc gacgcggagc tggtcatcct cgtgatgccc caggcggggt
     5821 cggggttcac ctctccgact ccacgccggc ggagcgctcg gagatggccg ggtgggcgac
     5881 gtagggctgc cgccgttcgc gctcacactg gttccggtat ctgcgacggc acctgatcga
     5941 cacccacacc gccgggccgc tgctctcccg ggcgctggcc gacggcgacg ctctacgagc
     6001 ggcaggtgcc catgggcgac ccgggagtga ccacgagctc cgtcggctcg cctaccggcc
     6061 cggcctgctg gtcatcgccg tcaagggcca cgtctctccc cctccccccc ccccgaactc
     6121 gaccgcttcc tcaccgagcg cgtggtccgg ctgatcactg tcctaccgcg accgggcccg
     6181 cctcccggcc agccgctgct cgaagtccgc cgacgagctg cgtgagtccg tcaacgacgc
     6241 ggcggccgcc caactcgact gggaacaaac acgcccggcc gcggcatcga gggcgcaggt
     6301 gttcgcgtcg gcccacgact tctggcgttg gccgccgccg tttgacgcaa gcgtgcctcc
     6361 ggccggggac ggcaggcctg aacaccgact ctcctcgttc gacgtcaaga tcgacaacta
     6421 cctggcgggc ggaccccgga cgccggccgc ccagtccggc cccgcccgga gctggtcgct
     6481 ccggcggcgg cccgggcgct gtgcggcacc tgcggctgtt ggctgccgac accgacgtgt
     6541 ggaccgacgt cacctggagc gtcggcgcca tcccggcagt gcgcccgctc ccgaccgccg
     6601 ctgacgtctg cccggcacct gatcgagtcg gtcgaggacg ccccaagggc caggtccccc
     6661 tggaacagca cggcggacgc ggcatcgggg gcgtcggagc ccgcgtcgcc caaccacttc
     6721 tcgccctgac cgccgccatt gggcagccca ccgcctccgg ccggcccatc acctggtccc
     6781 tgaccgccta cgaccactag cccgagttgc gcattactcg tctagtaccg tccgacggac
     6841 cgcgggaggg acgtccgcgc gggccggtcg cgggcgtccg gcgacgcggc gcgcccgcca
     6901 gcccggcggg cggggtcgcc tcgtgccccg tggacggcgc tgaccgtggg acgactggcg
     6961 tcccgggcgc tcgccggggc gctgccccgg gcacgctgtc gcggcgcact gccacggggc
     7021 gtcgtcgcgg ggccggcgcg aagagcacgc ggacgcgcgt ggggaggtcg acggacgaga
     7081 tgctgctact gctgacctgc cggggctcgg cggagatccg cgccacccac gaccgcaccc
     7141 tggagttcac cacggacagc gcgatctccg gcagggccag ttgtgtggtg ggcgtcgaca
     7201 ccgtgctggc caggggcggc cgggtcgccg gcccggtgcg gatcacgatc gcgtgcggcg
     7261 ggctggaggc cgaggtccgg gcgctggcca gctcggcgtg gctgcccggc ggccgggcgg
     7321 tggtccggcg cagcgggctg cgcctggcca acacgatggc caccgacgcc gacacgaccg
     7381 ccgccgacct gccccgcgag ctggtggccc tgctggcccg gccggacgcc gcgatcgagg
     7441 tgcgggtcag ccgcgacacc ggccggtggg acggccgggg cagcgtcgtg ctctgccacg
     7501 ccggcgtcga cgcggaccgc ctcgccgccg agctggccgc cgccgacgtg gtggtcgccg
     7561 aggacccgga ggcgcgagcg gtggccggcg acggggagaa cgtggtcacc gggccggtgc
     7621 gcgagcagga cctgctggag cacggcgggc gcgtcctggt gctcgcggcg gaggacctgc
     7681 cgggcgcctc ggtcgccggc ctgctcggcg agccggagcg gttcgcggtc gagtgcgtcg
     7741 ggctggcgtc cccgctggcg gtcgcggcgg catcgcccgc gcgcggtcgt ctgctcgtcg
     7801 gggaccgggg gaagtggcgg gaactgctgc gctcctcccc cgagagccgg ctcgcgctcc
     7861 gggtgcccgc cgcgtcgctg gaggcgctgt tcaccgacgc ggagcggctg cgcggcaccc
     7921 gcaccgccgc cctggccggg gcgacggccg cggccagcga acagccgcgc tggggcgggc
     7981 tggcgaccct gctcgccgac gcgccgcgca gcggcgacgt cgtgtgctgc ctcgacccca
     8041 ccccgggcag cggtgagggc gacgagcccg aggcggaccc ggtcgtcacc gcgctgctgg
     8101 agcagggcgt gcccgcccgc acggtcgcca tggcgctggc ccagcggccg ggctggaccc
     8161 ggaagaccgc gtacgacttc gtgctccggc accgcgcgcc gcgctgagct gggccgtccg
     8221 gtgagctggg ccgtccggtg agctgatcgc gagctacccg cgcggacagg tcggagggcg
     8281 gcgcgcggtt acgctgaccg gcatgcgccg cgtggtgggc aagcgggtcc tggagttctc
     8341 cgaagccgag ttcgaccagc tccggagtca gtacgacgag gtggtgctcg acgtcggcac
     8401 cggcgacggc aagcacccgt acaaggtcgc ccgccagcac ccgaaccagc tcgtcgtcgc
     8461 actggacgcc gacaagacca ggatggagcg gatgtcggcg aaggcggcgg ccaagccggc
     8521 gaagggcggc ctgcccaacc tgctctacct gtgggcgacc gcggagaagc tgccgccgct
     8581 gaccggcgtg ggcgagctgc acgtcctcat gccctggggc agcctgctgc gcggcatcct
     8641 cggctcctcg ccggagatgc tgcgggggct ggccgcggtc tgccggccgg acgccgcctt
     8701 cctcgtggcg ctgaacctgc acgcgtggcg gcccccggtg cccgaggtgg gcgagcaccc
     8761 cgaacccacc ccggagaccg tggacgaggg actggccgcc cgctacgcgc aggccggctg
     8821 gcagctcacc gactgccggt acctggccgc ggaggaggtg gcggccctgg agacctcctg
     8881 gacccgccgg ctgaactcct cccgggaccg gttcgacgtg ctcgccctca ccggcaagat
     8941 caacccgtga gcaccgcccc cgacggcgcc ggcgcgaaca cccgccggcc gccgggggcc
     9001 agctccgccc gccggccgtc gacctccacc ggcagggtca gcgggttgtc cccgtcggcg
     9061 accagctcca ggccgtcggc ggtcagcgcg accgtcagcc cgcgcccccg ccaccgcaac
     9121 gggacccgca gcgcggtgac gccctcgggg agccgggggg cgaaccgcag cacctcgccc
     9181 gacgcgtcgg cgccgaggaa cccgcgcacc aggaccagcc aggccccggc tcccgctccg
     9241 aggtggatgc cgttgcggaa gttgtccctg ggcgcgaagt cgaggttgta gcgcgcggtg
     9301 ccggcgagca ggcgggtggc cagcgggagg tcgcccgccc acgcggcggc gatcgcgtgc
     9361 gtcatcgggc tgagcgagct gccgtgcgcg gtgcggggct cgtagtagcg caggttccgc
     9421 tcgatctcct cgcgcgtgaa ccgctcggac agcaggacca tcgtctgcac gacgtcggcc
     9481 tgcttgacca gcccgctcag ccgccgctcg tcgttctcct tgaccgggcc ggggaggttg
     9541 tggcccggct cgaccgagca cagctcgtcc gggagctcga agtagcccgc gaagagcggc
     9601 cggacgccgt cgcgggcggg cggcaggtag acctccctgg ccgccaccgc ccactcctgg
     9661 agcacgtcct cgccgatccc ccgctcgcgc agggccgcgc ggacctcgct gtggtggccg
     9721 gccaactcgc gcagggtctc ggccgcccac gacagacccc agctcaccag ggcgttcgtg
     9781 ccgaagtcgt ggtcgacgtc gtagtggtac tcgtcgaacc ccatgatccc gcgcacggtg
     9841 cgcccgccga cctcggggtc gaaccgcagg aggcaggcga ggtaccgcgc ggtctccacg
     9901 agcagcggca cgcactcctc gcgcaggacg tcgcggtcgc cggtgatctc gacgtaggag
     9961 cgcagcccgt gcagcacgtc ggcgctggtg tggacgacct gcgcgcccgc gcgctcctcc
    10021 cactcgtcgt cccgcaggac gtcgcgcacc aggtgcgccg agccggactc gccgagcagg
    10081 tccgcctcct ccgggaagcg ggcgccctcg tagccggtgc gccgcgcgtg ctcgcgcgcc
    10141 gcgtccagcg tggcgacgcg gaaccgcagc atggccttgg ccgccgccgg atcggtccac
    10201 gcggcgtgcg gcagcgcgaa gaactccgtg ttgtagaaga agtgccccga gtggtactcg
    10261 ctgctcagcc ccctggccgg gacgttgtgg acggtccggc cgcggtcgat cgacccgaac
    10321 aggtggaact gcgagtaccg catgccctgc acgatcgccg ggtcgccctc gacctcggcg
    10381 tgccgccgcc agcgctcggc ccagatccgc tcgtgctcgg ccaccaccag gtcgatgtcg
    10441 ggcaccgcgt ccacgtcggg gtcgacggac acagcgtcgt cgtcgaagtt cgtgctgatc
    10501 acggcgacgg tgtccacgcg gatctcgcgc ccggccccgc cggcgaagcg cagcgcctcg
    10561 gcgtgccgga cccggccgaa gcagacgtcc cgtgcctccg gctcggccga cgccgccagc
    10621 accgccaacc gctcggtgat ctcctcctcg tggccgaagc tgcggacccg cgcgtccagc
    10681 cggccggggc ggtaccccag gtccagcggt tcggcgtggt gcacccggac ccggggcagc
    10741 tgcccgccca ggtcgccgtt cccggtcgac cagtccaccc cggtcaggac cgtgaccggg
    10801 gcgtcgtggt ccagcggggt caccgcgacg cgctggacca gggtggtggt gaactgcgcc
    10861 ggcagcaggg tggtcgtctc gatccgggtg tgccggccct gaccgtcgcg cacggtgacg
    10921 accagctcct ggcgggcccg gcgcaggtcg aggcgctgcc ggaactccgt cacccggtcc
    10981 gcggtcaccg ccagcgggac gccgtcgacc aggacggcgc ggaaggccgg ggtgggcgcg
    11041 ttgaccaggt gccgccgcac ggtcaccgcc ctggcgtaca tccgcgcgtg gtagaagccg
    11101 ggccaaccgc ctccggcgtc gaagtccgcg gtcgcgcgga cgccgatccg gccgttggac
    11161 agggcgaaca ggctctcgta gaagctgtcc tcggtccgcc ggtaggcggt gcgctcgatc
    11221 acccagccgg gatcggcctg gccgccgggg ccccggttcg ggtcgctcgc cgtgctcgtc
    11281 atcgtcccgc tcccccgact cgccactggt cctcgatcat ccgttccagg ctcgaccggg
    11341 tcggcgccca gccgagcagc tccctggccg cgccggtgtc ggccgccagc cacggctggt
    11401 ccgcgctgtt cgccgggccg tgcgccaccg ggacgcggcg gccggtgacg cgttcgaccg
    11461 ccgcgaccac ctcgcgcacg ctcgccgcga cggcgcccag gttgaccacc tcggccggcc
    11521 ggcgcgccgg cgcttcgacc gcgcgggcga ccgcgtcggc gacgtcggcg acgtgcacga
    11581 agtcccgcac cgtcgagccg tcgccgttga ccgggagaac agcgttctct cccgccgcga
    11641 cggacagcgc ccgcgcgacg agggtgctgt cgtccggccg acaaccgggg cggacgctgc
    11701 ccgccgcggt gaacaggcgc agcgagaccg ccgacagcgc gccggtcccc gcgtaccagc
    11761 cgacggcctg ctccgccgcg agcttcgtgg ccccgtacgc gctggtcggc agcgtcgggt
    11821 ggtcctcgcg gaccggcgcg tcgccggtcc gcccgtagac cgccccgctg gacaggaaca
    11881 ccagccgggc cgggccgtcc ccggcccggt gccgggcgac cagggcgtcc agcacgttga
    11941 gggtgcccac cacgttgacc cggtagtacc ggtccacgtc cacgccgctt ccccgcaccc
    12001 tggtcagccc ggcgaggtgg cagaccgcct cggcgccgtc gagcgcccgg agcaccgccg
    12061 gggcgtcggt caggtcggcc tggcggctcg gcgtgcccgc cggccacccg accggagtcc
    12121 ggtggccgac ggccgtgacg tcgtgcccgg cggcgagcag ccgcgcgagg accgcctggc
    12181 cgacgtaacc ggcggccccg gtcacgaaga tgcgcatgtc cttcctctgg ggctaggcag
    12241 acgtgggctc gatcgccggc gccgggaccg gtgctgggac cggcacggac agcccgaccg
    12301 cctggtccag caacgcgcgg tgcaggtcgg ccccggcgag gtcggcgccg gtgaggtccg
    12361 cctgctggaa cgaggcgtac tccaggtcgg cgtccctgag gtccgcgccc cgcagggagg
    12421 cgcgtttcag gtggccgcgc gcgaagcagg accgggccat cagcgcgttg tccagcacgc
    12481 cgtccgagac gttgacccgg tagccgtcga cctcggtgag gtcggcgccg gtcaggtcgc
    12541 agtgctccag cgacggcgcg tacgagaggt tggtcccggc gaggtcctcg tgccgcagca
    12601 ccgtggtcac cgcgctgagg gtctcgtagg tgtccgcgcg cagggcgcac agccaccgcc
    12661 cgacgtcgac gcggcggagg gtggaccgag gtccgtccgg ctcggtcagc gagagcaggc
    12721 ggtagagcaa cgccgtcgcc cggggcgaca ctccaccgtc ctccagcggc gacgtggtgg
    12781 gagcggccgg ccagtggcgg gccaacaact ccggcacgat ctcgcgcagc gcgtccgggt
    12841 gtcccgcgac cgcgtcgagc aggcggcgcg ccggactcat cgggtcgaac tccggccgcc
    12901 gcgcgagggc gtcgcacgcc tcgacgaccg cccgggcgtc gccggtcccg agagcggccg
    12961 cgacctcctc ggcgcggtcg gccagcgggc cggtcgccgg gtcgtcctcg tcctggcggg
    13021 gcagggtgag cagcaacgtg cccggcaacg cgtgccggac cacgaagcag gcgtcgctga
    13081 cgtagatcgc cagccgggtg ttcggcagcc gggagcgcag gcgctccagg aggttccgca
    13141 gcaccagccc gtcgaccccg cgcccgcccc atgccgccag gtccggggcg tccagcacca
    13201 ggacgtcggg gtgcggatca ttgtccacag tggacgcgaa cgcgtcggtc gagcccatct
    13261 ccgcgccggc caaccgaagg atctccgtag tgagccccga cgcggtcagg cgcgtcaaca
    13321 gcccggcgtc cgggcgtcgg cggccgtgcc gcgcggtgac caccagcagc ccgcccggcg
    13381 gcaggcgcgt cgtgaggagc tccgccgggg acgccggcgc gcgggcggcg acctcggcga
    13441 gcgtctcgtc cgggggctgc ccgtccagct cgccggccca gccccagacg ccggtcgcgg
    13501 cggcggtcac cgcgcccccg cccccgccca cacccgctcg ccgctggcca ggttccgcgc
    13561 gatcaggtcg agccacatca cgtactcggc cgtcatgtcc aggtcgcccc agaacaggtc
    13621 ggccacgtcg tcggtctcct cctcggacca gtagccgtac ggggtctgcc gctcgcacag
    13681 caggtcgccg atctgctgcg cgatctcgcg gtaccggggc ttcccggtca ggcggtagag
    13741 catcgccgcg gcgaccccgg ccttgccgca cgaggagtcg atgaacgcgt cgtcgtcaca
    13801 ggtctcgtcc atgtaggtca tcagctcggt ggccaggtcg aggtacttct ggtcctcggt
    13861 ggcctcgtgc agcgcggtca ggaagagcgc gggcagaccg atgaagtacc agtcgccctc
    13921 ggccttcctc accgagatcg tgacggcgtc gtcgctggtc agcacgttgc cctgcgcgtc
    13981 ggccacggcg tggaacaggt tctccctgtc cggctgcccg gcccacagcg agccgaggaa
    14041 gtcggcggcg gacctggcga ccgacagccg gccggtgtag agcgcggcga gaccgctgat
    14101 gctggtcgag accgagtcgc accggccgtc gccgggcacg gccggcccgt gggagcggaa
    14161 accgccggtc accgggttct gcatggtctc gacgaaggac atcagcttcg aggagaggcc
    14221 gaaccggccg agcacgtgcg cgccgatggt caggtagccg ttggcgtaga ggtagtggac
    14281 gtcgaggaag tactcctcct cgcgcggctg cgggatgtcg ccgtcggcct ggagcagcga
    14341 cgtcacgtag tccgcgaccg cgctcgcggc ctgggtgtgg ccggcggtgt gcagcgccca
    14401 catccccttg tagcaggact cgatgacggc ggtcctggag ggcagcgcgc cgttcgggcg
    14461 ctgccgctcc accagccagt tcgccgctcg ctgagccgcg ctcttcagct cctgggggct
    14521 gtttccgctc aacggagtct ccttagtcag ggaatggatg ggcgattctg gaagaaaccc
    14581 gctcgggtct cgcgccgacc gccgccgcgg ccggagaggg gcgggagccg cgacgaccgc
    14641 gggaccgacg tgccggcaat ggcgcacccg atcggcgtgg acatcccggg aagcggggtc
    14701 cggacgattc cgcgagcggg aaccgcgaac cgggaccgcg tttcgccggg agccgaagaa
    14761 tcaggtcggc gggacgggtg cgcgcatgac ggcgaatccg gccgacgagc ttccggagcg
    14821 aacgacatcg accacgggcg tcgggtggac cacggcgcgc cgctcggggc cggccgacgg
    14881 gacaacccac tggacaggcc gtacggcctg ctggttcggc gatgccggaa cccgcgcgag
    14941 ccgcggatgc ccgggaaacc gggcggcgtt tcgggacggg acgccgtcca cgcgaccgtt
    15001 cgtgaccaag aggtggccgc cccctcccag cttcccgcca cgtgcgaccg ggaaatcggc
    15061 atggatcgtc aacagcctgt tcgggtgccg aggatcgcac gcgttcacga cgcgtcgaaa
    15121 tacgccgaac gagggtaacg cagatcacac actcttttcc tggcgcgatg tcccgaagtg
    15181 ccgagaagag ctgttgtgaa tctttcgagc aataccggga atgacgcgac gggaggtagg
    15241 gtgcgcattg gtgcggattc gcgcttttgt cgactgattc ttgcgggaag atcgtgggtg
    15301 aactggggtg cgggcacggc tcgcggttgt gcggtaaggc gatatgagaa ttgacgacgt
    15361 cacgcgcccc ggcctcgccg gcggtgtcgt cgcgctgcgg gccgacgcct ccgcggagtg
    15421 gggggtgggg cacgtcgtcc gctgcctcgc cctcgccgag gaggtcctgg ccaggggcgg
    15481 ccggccggtg ctcgtcgccg acctcggcga cgtggcctgg ctggcggagg aggtccgggc
    15541 gcgcgggctc gcggtgcgcc ctccggcgag cgacccggcg gggttcgccg accagctcca
    15601 cgcgctcggc gcgcgcgcca cggtgatcga ctcctaccgg ctcggccccg agcactacac
    15661 ggcggcgcgc gcggtcgcgc cggtcgtcgc gctctacgac cgccactccg ggccggtccc
    15721 cggcgacgtg ctggtcgacc aggtcttcgg cgcggaacag gacccgccgc caccggacgc
    15781 cgaccaggcg acggtgctgc gcggacctcg gtacgcgctc atccgggacc tcgtccggcg
    15841 tcaccggcca gccacccgac ccgcggccat gcccctcgcc gggcgggcgc cccgggtgct
    15901 gctggtgctg ggcggcaccg acgcccgcgg cgcgaccggg gccctcaccg agatcctgct
    15961 ggcgtcctgc ccgtcgctcg acctcaccgt ggtcggcggc ggcctcgacg gccccgcgcc
    16021 ggccaccggc gccggccagc gcctgtcggt ccaccgaccg tcggccgagc tgccccggct
    16081 gatggccgag gccgacctgg tgatcagcgc ggccggcacc acgttggcgg agctctgctg
    16141 cgtgggcgcg gcggccgccg ccgtgtgggt ggtggacaac cagcttcccg tctaccgcag
    16201 cgcgctcgcc gccggctgcg tgcacggact gggctcgctc gcggaggtgc tggccgaccc
    16261 cgggcgcgcc ggcgcggccg tccgcgcgct gctggagtcg ccggagcgcc ggaccgcgct
    16321 ggccggcgcg gcgtgggagc tggtggacgg cgcgggccgc ggccgggtgg tcgacgctct
    16381 ggcggcccgg ctcgccgacc gccggcccgc cacccgctga tccagcgccc acggatctgg
    16441 cacccgctga ccccgcgccc caggagtccc cccggcagtc gacgcccccg acgacaggag
    16501 aacgaccgtg cccaggatcg acgagtcccg cctgcgtgat ctcctcgccg ccgccgccgg
    16561 ggtggcgccg gccgagctgg acggctggcc cggccgggcc ggctggctgg accgggcggc
    16621 cgcgatgctc accgactacg tggccggcgt gccgctcggg tacgtgctcg gggagatcca
    16681 ctacctgggc agggcgttcc gcagcgaccg ccgcgccctg gccgtccgcc ggtacagcga
    16741 gccgctggtg cggcggatcg tcgacgactt cgccggcgag ccggtgcgcg cggtggagat
    16801 cggctgcggg gccgccgccg ccatctgcac cctcgccaag gagctgaccg gcgagttcgt
    16861 cgggaccgac gtcgtaccgg aggcgctgga gctggccgag gagaacgcga cccggcaccg
    16921 ggccccggtc cggttcgtcg tgagcgacct gttcgacgcg ctcgacggcc ggttcgacgt
    16981 gatctacgcg aacctgcccc gccaccaccc gagcacgccc atgccggagg cccggtggga
    17041 gccctccgtc gcgctgtacg acgacagcgc cgagccgttc gggctgctcc ggcggttctt
    17101 cgccgaggtg ccggaccggc tgaccgagcg gggccggctg tacctggaga tcccgctgga
    17161 ccccgcgatc gcggacctgc tgccgggtga gccggtggta gacggcgacg gggacgactt
    17221 cgcccgggtg atcaccgcgg ccgacgcccg ccggctcccg gcgctggtcg accggctcac
    17281 ctggcccgag gggtgacggc caccgtcggg gaacgagtga ggactctggc ccgacgagtg
    17341 gggaccgccc gccgtggaag ccgccggtgt catacctggc accccgacgg acccgccgcc
    17401 tcggctactc ggccggaaac cgcacaccgg tcgacaccgg gaccagttcg gccaacgtgc
    17461 tcacggtggg gcagccgggc gcggcgacgc ccagcccgaa ccggtcgacc aggaccgcgg
    17521 tcatcccgac ctgttgtccg gcgagaacgc cggacagggc gtcgtccacc agcacgcagc
    17581 cgtcgggcgc ggcgccccac gccgccgcca cgcgacgcag cgcctccggc cgggggacgt
    17641 cgccgtagtg gccgtgcggg ccgaggctgt ggtgcagccg gtcgagcagc cagtcgccgc
    17701 cgtcgagtcg gggaaggcgc ttggccagca gctcgccggc gttgcgggag gccgtgcaga
    17761 acgccagcgg cgtgcccgcc agcgccgccg cgtcgaggaa gtccccggcg tcggggaaca
    17821 ggacggtctc ctcggcctgc tccaggaaca cctgctgctt gaccgcggcc agctcgtcga
    17881 ccagcgccgg cgggggcgcc agcccggcga gctccagcgc ggccctggcc ccgacctgcc
    17941 tcggccggcc cgcgatgtgc cggtggtacc gctccaccgt gatctcggcg gagcgctccg
    18001 gcgcgtggtc gcgcagcacc ctggccaggc cccggcgcca tgccggcagg tggggcgtgt
    18061 ccagcagcgt gccgtcgatg tcgaggacga ccagcgccgc gttctcggtg tcgcgcaccg
    18121 gctacctccc cgagtcgagg agcaggccgg cggcgcgggt cgaggagtcg aacacggcgt
    18181 cgtcggtcag cacgaagctc ccgccgacgg cgctgaccgc gtcgacctcc tcgaccaccc
    18241 gcgggtcccg catgttcgcg tagtcggcgc ccttgaagta gtagtcgggc cgcaacgcgc
    18301 ggatcagcgg gaccgcggtg tcgtcgtcgt tgagcagcac gtagtcgacg acctccagcg
    18361 cggccagcac ggtcagccgg gcctcgtcgt cgaagaccgg ccggttgggg cccttgttga
    18421 tgcgccgggc cgcggtgacc gagaccagga gccggtcggt gtgccccgcc gcctgggtca
    18481 ggtggtggac gtgtccgctg tggaggatgt cgaagcaccc gtggcacacg ccgagcgtga
    18541 tcttctgccg ggcgagctgt tcgcgcaggt cctgcgctgc cggcatcgtc aggaccttcg
    18601 tggaagtagg cacaccgacc accccagttt tctgtgaacg tgtcgcggga gacgggcggg
    18661 acgaacggga tcagggaccg gagccgggcg gccgctgccc ggcggcggac gcgcctccgt
    18721 cgggcgggtc cgccggggcc gcgccgccgg gtccggggac gcccgggttg agggcgccgg
    18781 ggttggggac accggggccc gggacgccgg ggccgaggtc gccgccacca cctcggccgg
    18841 ccaggacgcg ccggtagtgc gccacggtgc ggtcgacgcc gacgccgtcg ccgaagttct
    18901 cctccagcca cggccggccc gcgcgcaccc gcgcccggtg ctccgcgccc cgcgcgagta
    18961 cgtcgcggac cgcgcggacc agcgccggca cgtcctgcgg cggaaccagc agctcgggcg
    19021 cgaccgtgcc gacggtgtcc cggagcccgc cgaccccgta ggccaccacc gggaccccca
    19081 gcaccatcgc ctcgatcgcg ctgccgccca gctcctcgtg gaccgacggc atcaccagga
    19141 cgtcgatccc gctcatcgtc agcggaacct cgtggttggg caggaacccg gtgaacacga
    19201 accggtcgga gagcccggcc gcggccaccc gctcctccat cctcgggcgc tgcggcccgt
    19261 cgccgacgac gaggaacacg acgggctccg ccggcgggtc ggcggccagc cgggcggcca
    19321 gctcgacgaa gtgggcccag cccttctcgt gcgccacccg gccgacgtag ccgaccacct
    19381 tcgcgtcggc gggcagcccg gcggcgcgca gccgctcagc caccggaacc cccgcgtcca
    19441 ccgggggttc cgggtccacc gagtcgggca ccacgtcgac gcgcacggcg tgcgggcgca
    19501 gcgccgcccg gacgacgtcg gccgtgcgtg cggtcagggc gcacaccccg tccgcccgcc
    19561 gcagcgccca ccgctcgacc gcggcgacga accggtgctg ccactggtcg taccgggaca
    19621 tcggctggta gacgcccagc cgcgagcagt gcagcaccag gctgtagggc cgccgcagca
    19681 gggccgaggc gatcggcccg gccagcagcg cccagagctg gccgtcggcg tgcacctgga
    19741 tgaggtccgg ccgccggctc cgccgccggc gcgcgcactc ggccatcgcg ccgaggaacc
    19801 acgccaggtt caggccgacc aacccggtca gctccgaccg cagccggggc atcggggccc
    19861 tggtgatccg gacgaccagc cccggcgagt cctcccggac ccggggcagg ccggggaacc
    19921 cgaccgtgag cacctcctgc cgcacgccgc gccgcgccag ttgccgcgac agccggagga
    19981 tctgcacctg catcccgccg acggcgtcga actccgccgg ccaccggtcc acgcagtcgt
    20041 ggtggaagaa cggggtgagc cgcagcacgc gcaaccgcat cacctatccc tcgggccgcg
    20101 tgcgacggcc gatcgccgcc gccgacgcgg ggtgggcgaa ctcggagacc accgcgtcca
    20161 cgaccgcccg gtcggcgacg gtgagcggca ggccctccga ctggagcggg acgcccggcg
    20221 ccttgagcag caccatcacg tacccgtcgt cgccggctcc gctgaggtag ccgcgcttgt
    20281 tgtcgtagcg caggcggagc tggacgtcgg ccgggctgac gtgggccggg aacgccaggt
    20341 cgatccccat ccgggagatg aggtcccggt gcagctcgat gaggtcctcg ccggccagcc
    20401 cgagccggcg ggcgatctcg gcctcggcga gcatgcccag ccccacggcg gcgccgtgcg
    20461 agacctcgcc cttggcggcg tgttcgaggg cgtgccccac ggtgtgcccg tactccagga
    20521 ccaggccctg tttccgctcg tggacgtcgg cctcggtgac ctgcgccttg gccgcgatgc
    20581 tctcgtcgat gatccagcgc atcacgtcgt cgtcgtagcg ctggtccagc ggcaggtgcg
    20641 cggccagccg gtcgatcatg ctcggccgga tcgcgagggc gttcttgacc acctcgcaca
    20701 ggcccgaccg gatgtccctg gtgctcagcg tccgcaggaa agcggtgtcg gcgagcacct
    20761 ccaccggctg gtagaacgtg ccgaccaggt tcttgccgac cgagctgttg accgcctgct
    20821 tgagcgacag gaccgagtcc agcatcgcga cgatcgtcgt gggcacgtgc accagccgga
    20881 tgccgcggaa catcagcgcg gccatgaggc cggcgatgtt gccggtgatc ccgccgccga
    20941 gcgcgacgac gatgctgcgg cggtcggcgc ccagccgcaa cgcggtctcg accagctccg
    21001 cgagggtgcc cagccccttg ttctcctcac cgccctcgtg cacgagcagc tcggcggggc
    21061 cggccgtgcg gcggacgcgc tccaccaggt cggtgccgta gaggccggcg acggtggggt
    21121 cggcgaccac caggtaccgg ctggcctcca gctcggccag ccggtcgacg atctggtcga
    21181 cgcacgccgt gcccagccgg taggggaaac ggacgtctcc catggcgaca gtcgtgacct
    21241 tcatcccaac tcccccaacg tgagtccctt ccctcgctca ggcggcgagt tccgcgctgt
    21301 tggccaggac cttgcgcacc gcggccgcga tgtcgtgcat gtccgcctcg tcgccgagca
    21361 acgcggcgtg gtggagcgtg aaggcgcgtt gggcgagccc ctcgcagacc gggagctgga
    21421 agcgggaggc gtcgatccgc ttctcgtagt cctcgccgat cgcgtagcgc cgacggctgg
    21481 tcgggtcgta gagcttgttc accggcagcg gccggtacga ggggacgacc gagaagccca
    21541 gctccgccgt cagcgccgcg gtcacccgcg cgatgtccac gccgaccagc tcgccctcgg
    21601 gcagccgcgc gccgtagacg tagtaggtcc gcgagtccgt cccgggggag gtctgctgcg
    21661 ggcggcagcc gagctcggtg agcaggccgt cgagcacggc ggcgttgcgg gcgcggcggg
    21721 cgttgagctc gtcgagctcc ttgagctgct cgaccaggac cgcggcgtgg aactccgaga
    21781 ggcaccggtt gttgcccatc agctcgccgg tctcgaccag ctccatcgcg ccggcgctgg
    21841 gcgccgcggc ggggtagcac cggccgtcgg cccgcaggtg ctccacccgg cgcgccagct
    21901 cggcgtcgtc ggtgacgacc gcgccgccct cgccgctggt cagcaccttg ctgtgctgca
    21961 tgctgaaggt gccggcccgg ccgtgggtgc cgaccctgcg cccccggtac accgccccgt
    22021 gcgcctgcgc gcagtcctcg atcagcgcca ggccgtgccg gtcggcgatc tcccgcagcg
    22081 cggcgaggtc cgcgacggcg gagtacaggt gaaccacggc gacggccctg gtcgccggcg
    22141 tgatcgcggc ctccaccgcg gccgggtcca cgcaccaggt gtccgggtcg atgtcggcga
    22201 acacgggcac cgcgttgacc ccgacgacgg tggacgcgga ggcgacccag gacaggccgg
    22261 gcacgatcac ctcgtcgccg gcgccgaccc cgcacgcctc catggcgagc atcaggctgg
    22321 cggtgccgct ggccgccggc acgcagtgcg cggccccgac gtagtgggcg aagtcgcggg
    22381 cgaaccgccg ctcgaacgac tcgacgcccc ggtacggacc gctcagggac caccgggccg
    22441 aggcgagcac ctggctcagc gcctcggcgg tccccttcgc cggccgcggc cacagcggcc
    22501 actccctggt ccgcaccggt gttccctggt tgatcgcgag ctgcgcgggc atggttcccc
    22561 tttacggtga gcttcgtggt gtgggagtcc gccgggcccg gtgcgcgggg acgcgcggcg
    22621 cgcgtggtcg gaccgaccac gcaccgggtg ggcggtgtca gccgaggttg aagtacgagc
    22681 gcgtgttgcc gttcgtgcgc cgcagcgcga ggtccagggc gtccgcgtag tcgtcgaggc
    22741 cgaactcgtg gctcagcagc gcgtcggtgt tgatcgcgcc cgaggccagc acctcgatcg
    22801 cctcggcgaa ccggccgccg gggccgagcg agcccctgat cgacagcgcc ttgacggtgg
    22861 cgtggtgcgg ggccatcacg ccggtctcct cgacccggta gccgacgagc ccgatccggc
    22921 cgccggggcg cacgacctcg atcgcctcct ggaccgcgac ggggtagccc gacgcctcca
    22981 gcacgacgtc cggcaccagc tccgggcggc tctccaccag cgccgccaac tcacccggcg
    23041 ccgccgaggt cacggtccgc gcgccgagct cccgcgcccg ctccctccgc tcggtcaccg
    23101 gctcggagac ggtcgtgacc gtcgcgccgc gcagcgcggc ggcctgcatc agcagcagcc
    23161 cgatgccgcc cgcgcccagc accgcgacct tgtcgccctc cccgatcccc gcgttggcga
    23221 ccgcgtgcag ggccaccgcg agcggctcga cctggcaggc cgccttcagg tccagcgcgt
    23281 ccggcagccg gtacacgttg tgcacgggga tggtcatgta ctccgcgcac gcgccgtccc
    23341 ggttgaaccc gagctcctgg aggttgtcgc agagcaccgg ggtgccgcgc tcgcacgggg
    23401 cgcaccggct gcaggagacg gtgaggtcgc cggtcacctt cgcgccgcgc aggctctcgt
    23461 cggccccgtt gacctccacg acggtgccgc tccactcgtg gcccggcacg acggggtagg
    23521 tgaacccgtg ccacaccccg cggtacagcg acaggtcgct gccgcacagc gagttgtagg
    23581 cgatcttcac gagcgcctcg cccctcgccg gctccgggac gtccttgtcc cgcagcaggg
    23641 cgcgttccgg ggcgtcgaaa acgagtgcct tcatccggtc tctcccaagg tttctctgga
    23701 ccgccagcac gcggtcgcga cggagtggcc cggcggcgct cgcggcgccc gggccgggat
    23761 cggggttcct gggtcgggtc aaccgccggc cgggggcgcc gactcggccc ctggcaccgc
    23821 ctcggccggc gcagcctcgg cctcggcgag caggcgtcgc gcctcggcgc cgagcaggtc
    23881 cacaacctgg tcgacgtgcc agcggccgcg ctcgaagtcg gcgtgctccc tcgggtccct
    23941 gccctggatg ccggagcggg tcaggtggca ctccctgccg ggcaggtcgg agagatccag
    24001 ctcgtccagc cgctccaggt gcacgttctc cgggaacaac gccccgtaca cggaggtctc
    24061 caacgcgccg gcgtggtcca tgtccaggtg cagctcgggg tcgaacccgc agtcgtcgtc
    24121 cgagccgtcg aaggtgacca tgccgcgcag cccggtctcg ttcctgaccc gctccagggc
    24181 gcaggcgatg gggatcgtct gcttggtggt ccagtgcccg gacaccacca ccgccgcgcg
    24241 gaagcccaca gtggacagac cgcgcaggat gtcggtgtag agctggaaga tcgtctcgac
    24301 ccgcaggccg gggtgggtcg cgccgcgcca gttgccctgc atgaagcccc aggggctgcc
    24361 cggcagcacg atgccgccgt gccggcgcgc cgcgcgctcg cagatcgcgg tcgccttgtc
    24421 ggtgtcgacg ccgtagggca tgtgggcgct gtgccactcc agggagccga ccggcacgta
    24481 ggcgacggga gccgccgcga gccgggcctc gaactccctg ggcagcagcc ggtcgtaccg
    24541 cacctcgtcg gcgggagcgg tggtggcgga ggtagccgca gagtcggcgg tggtcacgcg
    24601 ctcaccgccc cggcgtactc ggcgcgcagg tccgcgacgg agagccactc gtcgttcttg
    24661 tccgacgtgt agctgaagcc gtcggggacc ggggtgccgc cggcggggac gtccgcctcc
    24721 tcggccagcg acgagcgcac gacgtagcgg tcgcccagcc ggaccgtccg ccgggcgtcc
    24781 gactcggaga tcatctcctc gtggagcttc tcgcccggcc ggatgcccac ctcgtggatc
    24841 gggctgcgcg gcgcgatcgc ctccgccagg tcgatgacgc gcatgctcgg aatgcgcgga
    24901 acgaagatct ccccgccgga catctggtcg aaggactcga cgatgaaccg gacggcggcc
    24961 tcgatgctga gccagaaccg ggtcatccgc ttgtcggtga tggtgatcgg ttttccggcg
    25021 gcggcgagct gtttgaacaa cgggatcacc gaaccgcggc tgccgagcac gttgccgtac
    25081 cgcacgacgc cgaacctggt cccccgccgg cccgcgtact cgctcgcggc gacgaagagc
    25141 ttgtccgcgc agagcttggt ggcgccgtag aggttgaccg ggctggacgc cttgtccgtg
    25201 gacagcgcca cgacccgcga gaccccggtc tcgacggcgg cgtcgatgac gttctgcgcg
    25261 ccgagcacgt tggtgcggat gtactcgatg cagttgcgtt ccgcggtgtc gacctgcttc
    25321 aacgcggcgg cgtgcaccac gtgctcgacg tcgcgcatgg cgtggcgcag ccggtccggg
    25381 tcgcggacgt cgccgatgac ccactccagg cggcggtcgt ggtcgaacgc ctcgcgcagc
    25441 tcgcgctgct tgagctcgtc gcgggagtag acgaccaccg agtcgcagcc gagggtgtcg
    25501 agcgcgttgc ggatgaaggc gcgaccgagg gagccggtcc cgccggtgat catcacccgg
    25561 cttccggtca ggacatgatg tgaggacaat tcttccccct tgtgctggtc ggccagtgtg
    25621 ggcgagaaag cggatcgagc cggattcgtc gaaatcaccg gggcctccgg gagaaccgca
    25681 tgcgaaaagc ggtggtgaaa ggttccgtga aaaccggggt tccgacgcgg cccacggccg
    25741 cgccagccgg ccgcgggtcg gcgccgaggg cgtcccgcgc gccaggcgcg gcccgccggt
    25801 cagctgtcag ctgtcagcgc cgcgtcgccc cgtcagcccg gcggcgcccc ggggacccgg
    25861 gcgggcgctg ggcgcgcagg aggcggccgg tccggtcgcc gccagccagc tcgacggcgc
    25921 cggccaccgc cgccaccgcg gcgtccaggc tgtccggtgc ctccggtccg cccatgtcgg
    25981 tggggatcca ccccgggtcg acggcgttga ccacgatccg gtcgggtcgc agcgcgatgg
    26041 ccaggttcct ggtcatcgcg ttcagggcgg ccttggccat ccggtagccg gtgaacaggc
    26101 cgtcgaaggt gtcctcgtcg gcgtcccggc tggtcacgtt caccacggcc gcgccgccgg
    26161 cggcgcgcag cagcggcagg aacgccctgg tcaccagcag cgggccgcag gcgttggtca
    26221 gcagcaggtc gagcgcgtcc ccaggccgga ggtcctggaa ctcctcctcc tcgtgccgga
    26281 acaccccggc gttgttgacc agggcgtgca gcggcccgcc gagctcggcc accgccgcga
    26341 cggcggcggc gacgctgccc gggtccgtca cgtccagcgc gacggcggac accggcgcgc
    26401 cccgaccacg cgctctcgcg agcaccggcc cgacgtcgcc gacccggcgg cagcccagga
    26461 cgaccgacca cccccggtcg gccaacgcct ccgctgcacg cagacccagg ccccggctgg
    26521 cgccggtgac cagcacgcgc ctgggacccg ccgccgtcac ccggaacccg cccacgtcga
    26581 cggcgcgcgc gaggacccgg gccaccccgg tccgccacgc cgttcccact cgccggccgc
    26641 cgccgcgacc ggtccaccgg tcggggtcgc cccgccggct ctcaccacgt tcccgcacct
    26701 ggtcaccatc ccgatcaccc gcccgcgggg cggttcttcc gcacgcgccg ccgcggcgcg
    26761 gcggttccgc gcggcggaca acgacgcgcg cccgcatccc aacgtcgacg gtggggggca
    26821 cgcgtgaacc gtgagcaaaa cgtccgccga tcggcgtccg ttttgtttcc tactcccgcc
    26881 ccgaccggcc gcggacggcg gtgggcgaga acacggcggc agcgtcggcg attccggaag
    26941 gggcagcgac gtcaaccggc ccgccacttc tggcgcggcc ggctcggcat cgtccggaac
    27001 cgcctgggga tatgttgttg tcggagctgt tctccactct gccgccgagt gcggcagagc
    27061 gggtgacccc ggtcgggaaa ttcggagcgg ggcagcgttc cgaagatcgt cttccgggct
    27121 cgagaacaac gaagcggacc ggctttcgcc tttccgtcgc cgtcctgttt ctgtcaacga
    27181 ccgcgggtcg ccgcagaagg cgcgacacgg gcggaatcgg agggggcagg cccgcgcccg
    27241 cggtcaacac cggggccacc ggcgaggcgc tcaccaggga ttttctaccc ccggccgcgt
    27301 cgtcacccgc cggcctcaac accgtggcga gcgaacccgc ctggtgtctt aaatggcccc
    27361 gaaagccgaa catgacgtga cggtacaacc ggggtcggac gggggcaagg caaaaaatca
    27421 ggggtctgtc ctgcctcttt cccggctacg tccgttcgag tgaaaatggt gccgaacggg
    27481 ctatctccta attagactcg ctcgcgtcaa gccaccggcg gcgaccccca gcgccgcaga
    27541 tcaggatggt gtgatgacag agagcgcgac gaagggggaa caccttcggt gagcgcccct
    27601 tcccgggctc gcgcaaccgt cggagaaacc gtgttcccgc tggtcgcggg acaggtggcg
    27661 tcgccattca ccggtttgcg ccgaccgtgc cggttccgcg tgttcccgta ctgcggagga
    27721 accgctggca cggttttgtt ccgcatattc cgaaggagtt ggtcgcgtga agttcgtgac
    27781 gctgcaggag gccgcaggac aggtctttga cgtctgcgtc gtcgggagtg gcgcctccgg
    27841 cgcggtcacg gcgttcacgc tggccgggcg cggcatgtcc gtgctcgtcg tcgagcaggg
    27901 cgacgtcatc ccgccgggcg gcaagatcga cgatcacctg gacccggaca gctgggccta
    27961 cgcctggcgg cacggccgct ggtggaccac cggctacccg tggtccgcgc aggccttcgg
    28021 cggcgggacc gtcttctacg ccggcgtgtc cttccggtac cacccgcgcg acttcgcgcc
    28081 cagccccgag ttcctgggcg cggcagccta cgagcactgg ggtctgaccc ggcaggacct
    28141 ggacccctac tacgactgga tcgaggacca gctcgccgtg gccgggccgt ccggggccac
    28201 cgtcgccgag taccagttcc cccgctacaa gcgggagaag ctgagctaca ccagccaggg
    28261 ccgcgtgctg gccgaggccg ccgcccggct cggctggcgg cccgtggcca ctcccctggc
    28321 catcagcggc gtcgccgacc gcttcacccg cggctgccag cagctcacgc cgtgcaccga
    28381 caacgcctgc ccggtcggcg cgaaggcgga cgtggcctcc cggctgctga gccgctgcga
    28441 cgacaacctg tccgtcctgt tgcgcaccag ggtcgcgcgg ctggtggcca cgcgccccgg
    28501 cgtggtggac tcggccgagg tcctgcacgc cgacgagcgg gacagcggca ccatccgggc
    28561 ccgccggttc gtcctggcgg ccaacgcgat ccagtccgcc gccctgctgc tgcgctccgc
    28621 ctcgcgcctg gagccggacg gcatgggcaa cagcagcggc atggtcggcc agcacctggc
    28681 catgaagaac agcgtctacc tccgcaccca cgtccggcgc gaggacgact accggcccct
    28741 gcaacaccgg tactccagca tgacgtcgct cgactcgatg tacgacccgg agttccccga
    28801 cgggatgggc ggcctgatct acgaggccaa cccgtgggac aacgtgaagg acaacgcgtt
    28861 catgccgctc caactggagt gcagcgtcgg cgaccggccg cgggccagga accaggtgcg
    28921 gctgagcaag gacctcgact cctacggcct gccgcgggtg gtcatggact acgtcgcgca
    28981 caagcgcgac ctggcccgcc tgcgcgtcct gcgggggcgc gcgagcgagc tgctgcgctc
    29041 gctgggcggc cgggtcaggc acgtgagcac caagtacgag ctgggcagcg cccacctgca
    29101 cggaaccctg cgctcggggc gcgacccccg ttcctcggtg acggacccgc tgggccgcct
    29161 gcacgactac gacaacgtct gggcggtgga tggcgcggtc ttccccttcg ccggcaacct
    29221 caatccgacg ctcaccatcc aggccaacgc ccggcggatc gcctccgcca tctcctgacc
    29281 caggcccccc gactggctcg gccgcaccgc tcccggtgcg gtccccccac gtgaagaggt
    29341 gcgacgcatg cggctcggca agttactgct ggtgagtccg aagacctcct tcggacgtga
    29401 tctgcaacgg acctacgccg gagggctcgg caccgtctgc aaggacgagg acttcctgct
    29461 gcccccgctc gacctgatgc ggctggccgg cgtcctgcgg gaggacgccg acgagatcgc
    29521 gatcgcggac gaggaggtca ccggcgtcgt cgccgcctcc cccggcagca cggtgatctg
    29581 ccacgtctcc ctgcccagcc tgctggagga cgccgagcgc atggcgacct tccgggagca
    29641 gggcgcgcgc tgctacgcct acacgagcat ccgcagcccc gtgcagtggc gggagctgtt
    29701 cgagcgggcc ggctgcgtcg gcatcctgct gcccgagtcg atctcgttcg cccgcgccgc
    29761 gctcgccggc gacgccaccg tccccggcct ggtcaccccg gagaacctgc tggagccgcg
    29821 gcaccaccag ccgcggttcg gcgacctggc ggccgagccg ctgcccgcgc gggacctcgt
    29881 cgaccacacg ccctacatgt tcccgccgat ctccctcaac gggatcacga gcatcaacgg
    29941 cagcttcggc tgcccctacc cgtgccgctt ctactgcccg tacccgctca gcgagggccg
    30001 caagatccgc acctacccgg tggagcggat cgtcgccgag ttccgccagt gcgccgagct
    30061 gggcatcacc gccgcggtct tccgcgaccc ggtgttctcc ttccaccgcg accgcacgat
    30121 cgagatgtgc cgggcgatcg aggccgccgg caccggggtg ccgtggtggt gcgagacccg
    30181 catcgaccgg ctcgacgagg aggtcgtcgc cgcgctcgtg gccgccggct gcgtcggcgt
    30241 cgaggtgggc gtggagagcg gcgacccgga gatgcaggcg acggccgtgc gcaagcggct
    30301 cgacctggac accgtccgcc ggttccacgc ggtggccagg aaggccgggc tgaagctggt
    30361 cttcctgttc ctgatcggcc tgcccaggga gaccaggatg tcgatccggc gcacgttcga
    30421 cttcatcctc gaactcggac tggcgcacac cgagttcaac ctcagcgtga tcacgccgta
    30481 cccgggaacc gagctgcacc agatcgccgt ggacaagggc tggatcgacg gctcgcagga
    30541 caacttcacc agccacaacg cggtcatgca cacggaccag ctcacgatcg gggacctgga
    30601 gcaggccagc cggttcgtcg acgagctgca cggggtgtgc aaggcggggc ccgcggagcg
    30661 ggccgagttc caggccaggc tgcacgcctg gtcgaccagc gacgcctgac gaccgacgag
    30721 agggacccac acgatgtcgc cgcacccgca gaagcgaaga tcccgcacca gcgcgctcct
    30781 cgcggtcgcc gccctcgcgg cggcgctctc cccgacgatc cccgccgtgg ccgacgacac
    30841 cgccgagggc ttcgccctgg cccccaacgc ggaccggacg caccacgtcc ggagcgcggt
    30901 caggggcggc aaggcccgca acgtcctgct gttcgtcggc gacggcatgg gcgactccga
    30961 gatcaccctg gcccgcaact acgagctggg ggccgccggc cggctgaacc tggaccggct
    31021 gcccctgacc ggcgcctaca ccacctactc ggtcgccaag ggcgacccgg ggcgcgtcga
    31081 gtacgtcacc gactcggcgg cggcggccac gggctacgcc atcggggcca agacctacaa
    31141 cggcgccgtg ggcgtcgacg cgcacggcag ggagcggccg acgatcctgg agctggccaa
    31201 gcgccggggc taccgcaccg gcaacgtcac caccgccgag ctccaggacg ccacccccgc
    31261 cgccctctcg gcgcacgtgc tcgaccgcac ctgccgaggc ccgcaggaca tgaaggagtg
    31321 cgcgccgaac gacaagcgga acggcggcgc gggctcgatc gccgagcagc aggtcgcgct
    31381 gcgggccgac gtgctcatgg gcggtggcgg caagtacttc gaccagcagg tcgccgccgg
    31441 ccagttcgcc gggcggaccg tgcgccagca ggcggtcgac tccggcttcc aggtgatcac
    31501 ctcggccgac cagatgcggg ccctcgaccg ggagcggccc gtactcggcg tgttcgccgc
    31561 cgagggtctg gacagcacct ggaccggccc gccggccaag gcgggcggga cgccgccgag
    31621 ccggtgcgcg gagaaccccg cccgccggaa ggaccagccg acgctggccg acatgacccg
    31681 tgcctcgatc gacctgctcg aacgccgatc ccgcggccac gacagggggt tcttcctcca
    31741 ggtcgagggc gcgcagatcg actggggcgc gcacgacggc ctgccctgcg agcagatcgg
    31801 cgagaccgtc cagttcgacc gggcggtggc cgtcggcatg gagttcgcgc ggcggcgccc
    31861 ggacacgctg gtcatcgtca ccgccgacca cgcgcagacc acccagatca tccccaacgg
    31921 ccagaagagc cccggcatga ccgccaccct catcaccaac gagggcggcc acatgacggt
    31981 caactacgcc accgggctgc ccggcgagct ccaggagcac accgggaccc aggtgcggat
    32041 cgccgggtac gggccccagg ccgccaacgt cgtcggcgtc accgaccaga ccgacctgtt
    32101 ccgcaccctg tccagggcga tgggagtccg ctgacggcgg acccgccgcc accacaacca
    32161 cgtcacctcg tcgccggccg gggacgcgct cgccgtcctc ggcggacctc ccctgccggc
    32221 ggcggggctc cacccaacga gagggggatg atgagcagcc acgtctcttt cgcccacgtg
    32281 gacacggaga acgccgctct cgtcgacgag ttcctgccgg tgctcaagga gcggctcgcc
    32341 ggcggggtgt tcatcggagg ggaggaggtc gaccggctgg agcgccggat cgcccgcctc
    32401 caccaggtcg agcacgcggt cgcggtcaac tccggcaccg acgcgctccg gctcaccttc
    32461 cgcgcgttgg ggattccccg cggcaccacc gggatcaccg tcgcgaacac cttcgtcgcc
    32521 acggtcggcg ccctgctgtc ggaggggatc aaccccctgc tcgtcgacgt cggcgccgac
    32581 gagaacgtcg acgtggcggc gctggaggag gcgatcaccc cggacaccag cgtggtcgtc
    32641 gccgtgcacc tgcgcggcct gcccgccgag atcgcggcgg tccgggagat ctgcgcgcgc
    32701 cgcggcgtcc acctcgtcga ggactgcgcg caggcggtgc tggcctccgc cggcggcgtc
    32761 ccggtcggcg cgttcggcgt cgccgggtgc ttcagcctgc acccgctgaa gaacctcggc
    32821 gcctgcggcg acgccggcgt ggtcgtgacc aacgacgacg cgctggccgc cgagctgcgg
    32881 ttgctgcgca accacggcct gcgggaccgg gacaccgtgg tccgctgggg cgagaactcc
    32941 cggctggacg ccctccaggc gagcctgctc aacgtcaagc tcgaccacct ggaggagtgg
    33001 acccgacggc ggcgggacct cgccgcccgc tacgacgagc tcctggccga cctccccctg
    33061 gtcctgccgc cccgccccga ggaccgcgtg cacgtgtacc accggtactc cgtcatgacc
    33121 gagcaccggg acgccctccg ggcccacctg gccgacgcgg gcgtccagac cgccgtgcac
    33181 taccccatcc cgatccaccg gcagcccgcc gcccgcggcg gccagctccg gatcgccgga
    33241 cgcgggctgg ccgtgaccga gcggcaggcc ggccagatcc tctcgctccc gctgcacccc
    33301 ctcatgccgg agcgcgacct gcgcgccacc gcgcgggagg tccgggcctt cttcgagagc
    33361 cggccccggt agcgccgcct tcgccccagt ccgtccgaca caccccagcg ggagttgacg
    33421 tctcatgaac aagcacgccg gtcccggcct cgtcctgatc acgggcggcg ccggctacat
    33481 cggctcggtc ctcacccggc ggctgctgga caagcgggtc cgggtgcggg tgctcgactc
    33541 gcggatcttc ggcgacggcc tgcgggacct cgccgacccc ggcctggaga acgtccaggg
    33601 cgacatccgc gacgccgacc tgttccggac ggcactgcgg gacgtcgacg tcgtcgtcca
    33661 cctcgcggcc gtggccaacg accccagctt cgacctgaac cccgagctgg gccgctcggt
    33721 gaacttcgag tgcctcgacc acgtcatgcg gctctcgaag gaggccggcg tccgccgctt
    33781 cgtctacgcc tcctcggcca gcgtctacgg gatcagcgac tcccccgagg tcgacgagtc
    33841 ccacccgctg gtgccgatca ccgactacaa ccggtacaag gcactgggcg aggaaatcct
    33901 cttccccctc accgacacct cgttcgagac cgtcgcgctc cgcgcggcga ccgtgtgcgg
    33961 cgtgtccacc cgccagcgcc tcgacctcac ggtcaacctg ctgaccgccc aggccgtggg
    34021 caaccgcgag atcaccgtct tcggcggcgc ccagtaccgc cccaacgtcc acatcgacga
    34081 cctggtcgag gtctaccaac gactggtcct ggacgactcg ctgggcgccc tcaacggcgc
    34141 ccccatcaac gtcggcaacg agaacctccc ggtcgccgac atcgcgaagg tcatcgccac
    34201 cagggtcacc gccaaactcg gcgccgaggt caccaccacg accaccccca ccgacgaccg
    34261 ccgctcctac cgcctgacct cccgccgcct ccaccagctc ctgggcatca cccccacccg
    34321 caccgtcgcc gacgccagcg acgacgtcac cgacgccatc ctcgacggcc gcctccccaa
    34381 ccccctcacg gaagcccgtt actacaacgt ccgctggatg aaagaccccc gcagccagga
    34441 cctcctcacc tacaccccct gaccgccgac aaccggggcg gggctgcctc ccaaatgatc
    34501 gaagagcgtt tcggaatcag ctgaatcagc tttcgcagtg ccactcatgg aggcgagtcc
    34561 gcagattcga agggggtgtg cctacgccac gccacctctc gtcagtcgag aacgacaaac
    34621 aacggcaagg gcgaaaacct ccgctgatcc agggttgtcg cccgatcaac agcggcatca
    34681 gcacgacctc acgccaccct ggcgggcatc gacccaagtg aggcgagaag gcctgccgag
    34741 aaagaagaaa gcctggccag gacgtgtcct gaccaggctt tcttctccgt gtgcctagca
    34801 cgagtggagc tgacgggatt cgaacccgtg acccccacac tgccagtgtg gtgcgctacc
    34861 aactgcgcta cagcccctcg gtggtgcccg catacgttac aacacggccc gcgccccggc
    34921 ttcaccccat cccgccgccg tgcccagagc cagggtggac gcctcgtcat gccgatcacc
    34981 agggcgtgcc gcgaggaggc ggtgaccgaa cctggggtcg gggcggggct cgggaatgcc
    35041 gaaggccctg ggcgggaagc ggtggagctt cctgaccagg gccttcgggg ctatctcaac
    35101 cgagtggagc tgacgggatt cgaacccgtg acccccacac tgccagtgtg gtgcgctacc
    35161 aactgcgcta cagccccttg cggtcttgct ccgctctctc ggggtttccc cctcggcggt
    35221 gcgctgcata cgctacaaca cgtgcccccg aaaaacgaaa tcggggggcg gtccccgtcc
    35281 aacagatcta gctcacaacg ccctgacctg ctagaacagg ccagatgacg gttgagcgca
    35341 gtgtcgtgcc ccacctcgtc gaccccgacg cggagggcgc gaaccccgag cggcggcgtg
    35401 agctgcagca gcaccggctg cgcggcctgg tggaccggct cctcgccgcg gacggggtgc
    35461 aggcggagcg cctgcgggcc gcgggggtcc gccagggcgc cgacgtgacg ttgcgggacc
    35521 tcccccgact gcccaccctg agcaagccgg acctctggga gcactacccg ttcggcctcc
    35581 ggctggcccc ggagaccgac atcgtgtgcg tgcacgggtc gtcgggcacg ggcggacggc
    35641 cgacgctgat cccctacacc gcccacgacc tggaggtctg ggcccaggtg atggcccgcg
    35701 ccctgggcgg ggccggtgcg acgcgcacga gcgtcgtgca ctgcgcgtac ggctacgggc
    35761 tcttcaccgg cgggctcggc atccaccacg gggcaatccg gctcggcgcg acggtcgtgc
    35821 cgatgtcggg cggcatgacc gaccgccagc tccgcctgct cctcgacctc cgcgcggacg
    35881 tgctgtgctg cacgccgtcc tacgccgtcc acctgggcga ggcgctgcgg gcggcgggga
    35941 tcgaaccgga cgagctggcg ctgcggaccg gcgtgttcgg ggcggagccg tggaccgacg
    36001 ggatgcgggc ccagatcgag cagtcgctcg ggctgcgggc gctggacatc tacgggctgt
    36061 cggaggtgat cggaccgggc gtggcctgcg agtcgctgga ctccgacggc atgctcaacg
    36121 tcgccgagga ccacttctac gtggaggccg tcgacgacga gggccgcccg gtgcccgacg
    36181 gcgcccccgg cgagctggtg ttcaccacgc tcaccaagac cggcatgccg ctgctgcgct
    36241 accgcacggg cgacatcgcc cgcctcgccg gccccgcgcc cggctcgccc cgcacgctgc
    36301 ggcgcatgag caagctgctg ggccgccggg acgacatgct cgtcgtccga ggtgtgaacg
    36361 tgttcccgtc ggagatcgag gcggtgctgc tggccgacga gcgggtcgcg ccgcactacc
    36421 tggtcgtgga ggaccgccgg gaccccgcac ggccggagct gcggatcgcc gtggagccct
    36481 tcgcggagtc ggtggccgtc gacgaggcgg agacgctgcg gcacgacctg gtcggcgcac
    36541 tgcgcgcgcg gctcggcatc ggctgcgcgg tcaccgtgct cccgccgggc ggcgtgccgc
    36601 gctcggagac cggcaaggcc cgccggctgg cccggtggac cgggggcgag ccgcccgtgc
    36661 gcggcctggg ctaggcccgc gctgggctcc ggaaccgagg ccggaaagac aaaaacgggg
    36721 gtgcgccggg ccccctacac ccccgtcgcg cggcggagat cagccctggc cggactgctc
    36781 gatcgccttc ttcagccact cggcgtcctg caggtcgacc atcgtgccgt tcacggcgat
    36841 ggtcggggtg ccgaagctct tgccctgcgc gctctcccgc tggagggccg ggttgttgcc
    36901 ggcggcctcc agctgcttct tgatctgctc gttgtacttg ccgccccgca cggccgactc
    36961 gaagtcgccg ccggagatgc cgaccgcctg ccccagcttg acgagctggt cctgggtgta
    37021 gcccttccca ccctccttgg gctgggtgcg gaacaggctg gcgtggaagt cggggaactt
    37081 gccggtgccg gccgccgcga tcgccgcgtt ggccgcctcc agcgagtagc cggccgggtt
    37141 cgagtaccgg tcgagcaggt tgaggatgtg gtagcgcgcc ttgaccttgc cgtcggcgac
    37201 ggccttctcc agctgctcgc cgtagagctt ctcgaacgag ccgcaggccg ggcacaggaa
    37261 gtcctcgtag acgtccacgg tgaccttggc cgactcgttg ccggccagca ccgtgccgtc
    37321 gtcctccacc ttggtggggt actgcgcgtg cgcggcggtc accgggatgt ccccggcccc
    37381 gccggaggtg ctgctgttcc gggtgtagag cacgccgccg atcacggcga cggccatcac
    37441 caccacgatg accacgccga tgatgacgtt gcggcggtcg ttgccgccgc gtgccgcggc
    37501 caccgccctc gccgcctgcg tggtctgctt ccgcttccgc gcggtccgtt cggcgccgcc
    37561 cacgtccagc atccctccta cgactcggcc gggacgggtt cgtcccggtc gtcaccatca
    37621 tccccgtcgc gcgccggacg gcccaggccc agccagccgt cgacggacag cagcgagcgc
    37681 ggccggacga gcagccagac ggccagcgcc aggaaaccgg tgtccctggc cagttcctcg
    37741 gggtagcggg tctcgccggg ggcgacgtcg ccgccgccgc cgaagcaccc gcagtcgatg
    37801 ctcagccccc gtgcccacgc ctgcgtgatg ccggcgacga acgcgagcag caccaggcag
    37861 gacaacgccg cgacgacgcg cgtgcccacg ccgaacagca ccaggacgcc gagtcccagc
    37921 tcgacgaacg gcagcacggc cgccaccggc ccggccaggg cgtccggcag cacccggaac
    37981 gcctgcacgg acaggtaggt ccgctccggg gccgcggcct tgatcgcgcc ggagacgagc
    38041 cagaccgcgg ccagtccgaa ccggaccagc gtgccgagca ggtccccgac cgaccggcgg
    38101 gcgggcattc cgacagccat cggcttcgcc acgcggcgaa gggtaccgac gcactctgag
    38161 gaaacgctta accaccctgc gtcactcggg tgataccggt caccgtcacc cgctcctcac
    38221 cgagcgcaac ggccttctgt ctcgatccag tagctctgag ctgccttttc tcaggctagc
    38281 cacaccttcc caaggctgtc ctgagccggc tttcgctccc tacagtggcg tcgtggcaca
    38341 gaccgagaag gtgggccacg gggaaatcgg gcacatccac tccgacgtct ccgggggctg
    38401 gctgcggccg gcggtcttcg gcgcgatgga cggcctggtc accaacatcg cgctggtggc
    38461 cggcgtcggg ggcggcgggg ccggacccga cgtggtcgtg ctgtccgggg tggccggcct
    38521 ggtcgccgga gccctctcga tggcgatcgg cgagtacacg tcggtggaga cccagaacga
    38581 cgcggtgcgc gccgaggtcg cggtggaacg ggcggaactg cgcgacaacc ccgaagggga
    38641 gcgggccgaa ctggtcgagg cgtacgtcgc gatggggctg acccggccga cggccgagcg
    38701 cgtggccgcc gaggtccacg cgaacccgga gctcgcggtg cgggttcacg tcacccagga
    38761 gctgggcgtc aatccggacg aacagccctc gccgtggacg gccgccctcc tgtccttcct
    38821 ctgcttctcc ctcggcgcgc tgaccccgct ggcgccgttc ctcctcgggt tcgcctcgct
    38881 gccggccggc ctgctcgtcg gcggcgcggg gctgttcgtc gccggcgccc tggtcgcgcg
    38941 gtggacgact cgttcgtggt ggcgcaacgg cctgcggcag ctcgccctcg gcgcgctcgc
    39001 ggcggtcgcc accttcctcg tcggctcggt cgtcggcgtc gtcacgacct gacccaccag
    39061 cccggcccac ccgtgggccg tggccgtggc cgtggccgtg gccgtggccg tggcgatcat
    39121 ggccgagatg ttatggccct ttgttatggc tcggcctatt cccttaaccc attcgggttg
    39181 caagcatcct ccgctgaatg actcatcgtg ccgcccctct tactgagcga agtggaccag
    39241 tccaccaaaa ggggcggacc cctgcacacg aggaggatgc atgtccgcac gcaccagact
    39301 gcggggtcga acactcggcg tcgccgccac cctcgcggcg ctggccgccg tcgcgctcac
    39361 cggcgcggcc ggctccgcgg tcgccgcgcc cgccgagcag ctctccggcg gccagctcgc
    39421 cgccgtggac tacctgagcg gccggggcct cgaccgggcc gaggcggtgc gccgggtgct
    39481 cgcccaggag gggcagaccc gcaccgcgac ccagctcgcc gacaagctcg gcgcgcgggt
    39541 ggccggctcc tacgtcgacc agggatcggg cgccctggtc gtcaacgtca ccgacgacgg
    39601 cgcggccgac gaggtgcgcc gctccggcgc gacggcgaag aaggtcgacc gcggcgtcac
    39661 ggacctcaac gcggccaagg ccaggctcga ccaggccggc aaggccgcgc ggggcgcgag
    39721 ctggtacgtc gacgtgccga acaaccaggt cgtggtccag gctcccgccg gcgacagctc
    39781 ggccggcgtg accgacctgc tgcgcacggc ggaggcgctg ggcggcacgg cccgcgtgga
    39841 gcgcgtccag ggcaaggcca ccacccaggc caccaacctc tacggcggcc agcagatcga
    39901 gttcagcgtc aacggcagcg gctacgtgtg ctcggacggc ttcaacgcca ccgaccgctc
    39961 cggccgggcc gtgatgatc
//
