BGC0000698: hygromycin A biosynthetic gene cluster from Streptomyces hygroscopicus
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Location: 1 - 39,151 nt. (total: 39,151 nt).
This entry is originally from NCBI GenBank DQ314862.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
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KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000698
Short description hygromycin A biosynthetic gene cluster from Streptomyces hygroscopicus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Saccharide
Loci NCBI GenBank: DQ314862.1
Compounds
  • hygromycin A
Species Streptomyces hygroscopicus [taxonomy]
References
Chemical products information
hygromycin A
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C23H29N1O12
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABC42538.1
 2270 - 3397 (-) putative AfsR regulatory protein
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  • ABC42539.1
 3717 - 4916 (-) putative p-hydroxybenzoate hydroxylase
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  • ABC42540.1
 5308 - 6279 (+) putative regulatory protein
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  • ABC42541.1
 6452 - 6973 (+) putative chorismate lyase
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  • ABC42542.1
 7011 - 8069 (+) putative mannose dehydratase
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  • ABC42543.1
 8342 - 9091 (+) putative methyltransferase
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  • ABC42544.1
 9084 - 10823 (+) unknown
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  • ABC42545.1
 10911 - 12146 (+) putative aminotransferase
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  • ABC42546.1
 12149 - 12400 (+) putative acyl carrier protein
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  • ABC42547.1
 12397 - 13533 (+) putative beta-ketoacyl synthase 1
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  • ABC42548.1
 13533 - 14291 (+) unknown
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  • ABC42549.1
 14294 - 15649 (+) putative Co-A ligase
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  • ABC42550.1
 15715 - 16005 (+) putative acyl carrier protein
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  • ABC42551.1
 16002 - 17045 (+) putative 3-hydroyacyl ACP dehydratase
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  • ABC42552.1
 17012 - 17782 (+) putative 3-ketoacyl ACP reductase
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  • ABC42553.1
 17817 - 19112 (+) putative glycosyltransferase
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  • ABC42554.1
 19109 - 20101 (+) putative myo-inositol dehydrogenase
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  • ABC42555.1
 20193 - 21284 (+) putative myo-inositol-1-phosphate synthase
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  • ABC42556.1
 21344 - 22594 (+) putative transmembrane protein
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  • ABC42557.1
 22599 - 23714 (+) putative transglucosylase
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  • ABC42558.1
 23787 - 24338 (-) putative phosphotransferase
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  • ABC42559.1
 24603 - 25778 (+) putative acyltransferase
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  • ABC42560.1
 25788 - 26765 (+) putative fucose synthase
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  • ABC42561.1
 26786 - 27649 (-) unknown
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  • ABC42562.1
 27762 - 28403 (+) putative myo-inositol-1-phosphatase
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  • ABC42563.1
 28423 - 29238 (-) putative short chain dehydrogenase
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  • ABC42564.1
 29701 - 30906 (+) putative DAHP synthase
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  • ABC42565.1
 30998 - 32710 (+) putative ABC transporter
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  • ABC42566.1
 32643 - 33779 (-) putative methyltransferase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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