LOCUS       BGC0000702             25467 bp    DNA     linear   BCT 01-JUN-2004
DEFINITION  Streptomyces kanamyceticus kanamycin biosynthetic gene cluster,
            complete cds.
ACCESSION   BGC0000702
VERSION     BGC0000702
KEYWORDS    .
SOURCE      Streptomyces kanamyceticus
  ORGANISM  Streptomyces kanamyceticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:04:25
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..25467
                     /db_xref="taxon:1967"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces kanamyceticus"
     protocluster    1..25467
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4525:16756]"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4526..16756
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
     cand_cluster    1..25467
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /kind="single"
                     /product="2dos"
                     /protoclusters="1"
                     /tool="antismash"
     subregion       1..25467
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000702"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..25467
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="2dos"
                     /region_number="1"
                     /rules="((DOIS or DHQ_synthase or ValA or salQ) and
                     DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            3..533
                     /gene="kac"
     CDS             3..533
                     /codon_start=1
                     /gene="kac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 61;
                     E-value: 2.2e-18)"
                     /gene_kind="biosynthetic-additional"
                     /product="aminoglycoside 6'-N-acetyltransferase"
                     /protein_id="BAD20749.1"
                     /transl_table=11
                     /translation="MRAHRSCCIRRRGLGHNAGVELNGEKVLLRPVLDSDVKKLDKIVR
                     EPEVAAWWSTPDDYEEMLAITLDGEVIGAVQYEEEEDPEFRHAGIDIFLTASRHGLGLG
                     TDTVRTVARWLIDERGHHRITIDPAVANAGAIRSYSKVGFKPVGVMRSYARDHTSGVWQ
                     DALLMDLLAEELV"
     CDS             complement(599..1747)
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF2"
                     /product="hypothetical protein"
                     /protein_id="BAD20750.1"
                     /transl_table=11
                     /translation="MAQYVSAAAMGAVVLLRAPAAARSPAQRGLWLAVATAAVAMALQL
                     PVVIRAALDLTGSVHEVGLARNLFGVLSAGCVLYFVTAAAQHRWWRWGLVTSVALVVLA
                     LVLLDQVREQHDNPGGPSSLSAYWAILMGSHIVANTVCVHVCLWQGCRASAPSLRLSLW
                     IFGAGTALVGIYWCVALGRLIIGEPPLRNLSLLMSLHGFLRAAALLVPLWGSMRSQPSQ
                     IRTLWVLWPLWRTLVQAVPHVALHRRRSRIVEVVWPRAPRRLAVYRRMIEIRDAILSLH
                     GYVHPALPGAVKSRVEQLGLHGRSADAMTLACLLHVALRARRTGAAKDFDASLSHGWDS
                     VNISGEESFLLELARAFRTPVARSLAGQLGGRTGGLTEVGDG"
     CDS             complement(1767..2354)
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF3"
                     /product="hypothetical protein"
                     /protein_id="BAD20751.1"
                     /transl_table=11
                     /translation="MHVRRTAYYRCPAQGLRKEHMSYIYVKLRQRCQAIVDGLSLPHPF
                     TVESFCTRLAAQRQRPLHLHALPRQAAQAGACGLWLATDIDDHIFFEQRTARVHQDHII
                     LHEIGHMLFGHQSLELGEGWGDAPQLFGDLSPQLIQRLLARTDYTTRREQEAEMLASLI
                     RTRGEQPAGERHADDVLHYLGEALGVGATRGG"
     CDS             2380..2592
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF4"
                     /product="hypothetical protein"
                     /protein_id="BAD20752.1"
                     /transl_table=11
                     /translation="MLRGARGMRSIHSVCWGPRPSSSAGGDRFWIFRASFTMTSNASKV
                     EGERPSARSARLRIRLSLRAVASAS"
     CDS             3322..4431
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF5"
                     /product="transcriptional regulator"
                     /protein_id="BAD20753.1"
                     /transl_table=11
                     /translation="MDFRLLTEKGPALAQQVHGSAPATVRESDIQAASLPPESKSELFQ
                     RSSVRVPLDLLLPAVSPRIAGVDERHVRSLAGIEAPLPPIVVHRATLRVIDGTHRLLAA
                     RARGETDVEVQFFDGGEADAFVLAVALNNAQGLALSPADRSTAAARIIASHPHWSDRRI
                     ARVTGLAASTVGGVRRRSTARTAQPNARLGMDGRIRPQDIAQRRRLAGQFLAEQPGASL
                     RTVAKAAGISLSTAHDVRTRLRAGDDPLPPALSRPTRPPAAPDSAADAADRPAKPSSAR
                     SPRSPGRAPVAADLLDRLRKDPSLRFTEDGRILLHWLGAAVLREHGAARFARCVPPHRT
                     AAMAALARSCAEGWLRLAESLDQRGRSDA"
     CDS             4526..5557
                     /NRPS_PKS="Domain: PKS_ER (113-261). E-value: 3e-11. Score:
                     34.9. Matches aSDomain: nrpspksdomains_BAD20754.1_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADSI-DH"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 328.3; E-value:
                     7.8e-100)"
                     /gene_kind="biosynthetic"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF6"
                     /product="dehydrogenase"
                     /protein_id="BAD20754.1"
                     /sec_met_domain="ADSI-DH (E-value: 5.2e-177, bitscore:
                     578.3, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 7.5e-27, bitscore: 84.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 7.9e-24, bitscore:
                     74.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVFHSPEKATFEQRDVPTPRPGEALVHIAYNSICGSDLSLYR
                     GVWHGFGYPVVPGHEWSGTVVEINGANGHDQSLVGKNVVGDLTCACGNCAACGRGTPVL
                     CENLQELGFTKDGACAEYMTIPVDNLRPLPDALSLRSACQVEPLAVALNAVSIAGVAPG
                     DRVAVMGAGGIGLMLMQVARHLGGEVTVVSEPVAERRAVAGQLGATELCSAEPGQLAEL
                     VARRPELTPDVVLEASGYPAALQEAIEVVRPGGRIGLIGYRVEETGPMSPQHIAVKALT
                     LRGSLGPGGRFDDAVELLAKGDDIAVEPLLSHEFGLADYATALDLALSRTNGNVRSFFN
                     LRD"
     aSDomain        4865..5308
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BAD20754.1_PKS_ER.1"
                     /evalue="3.00E-11"
                     /label="BAD20754.1_PKS_ER.1"
                     /locus_tag="BAD20754.1"
                     /protein_end="261"
                     /protein_start="113"
                     /score="34.9"
                     /tool="antismash"
                     /translation="TKDGACAEYMTIPVDNLRPLPDALSLRSACQVEPLAVALNAVSIA
                     GVAPGDRVAVMGAGGIGLMLMQVARHLGGEVTVVSEPVAERRAVAGQLGATELCSAEPG
                     QLAELVARRPELTPDVVLEASGYPAALQEAIEVVRPGGRIGLIG"
     CDS             5656..6897
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 60.5; E-value: 1.8e-18)"
                     /gene_kind="transport"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF7"
                     /product="transport protein"
                     /protein_id="BAD20755.1"
                     /transl_table=11
                     /translation="MSVSRGQRANATAIRLWTFMGLMELVPLFPLYPLLFSDHGLSGSA
                     ISSLLVLWSMTTFVLEIPSGALGDLLSRRLLLAFSVLLRAGGFSLWFIAPGYWSFAVGF
                     LCWGVCDALTSGTLESLVYDELQDRGEGHAYGPVMGTGRAISLLATLTALLLAGPLFVL
                     GGYGLVGAVSVGAGVAATITALTFPNPPRHEIESERGGFHRYLATFKAGFGEVRRERAV
                     MRLVLIAAILQSMTAIDEYFPLLAHENGAAKSLIPVLVAIPVLCASVGSWIAGRSTGVS
                     RRTAFLTVAATGPLLLLGAQSHHQWGMLSIAVAFGIIQWGIVVSGLWLQDAIVGSARAT
                     ITSVAGFGAEVSSVGWYLAAATALTVTDVSGLTSWFSLPCLLIAGLTWFWFPERPASEP
                     TEPTEPQPTTYSKR"
     CDS             6903..8081
                     /NRPS_PKS="Domain: Aminotran_3 (37-336). E-value: 1.6e-46.
                     Score: 150.7. Matches aSDomain:
                     nrpspksdomains_BAD20756.1_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 294.4;
                     E-value: 2.1e-89)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF8"
                     /product="aminotransferase"
                     /protein_id="BAD20756.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.9e-49, bitscore:
                     158.4, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.1e-09, bitscore:
                     28.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHPVLDWSRSAEHLRRSHGVTTDPRPDEDGHYPCVLTRGSGTR
                     VYDLDGNAYLDLTGSFGSVLIGHAEPAVVRAVTDVLSEGNLFYTGASPRRLALAERLLD
                     WFPWSEQAIFYRTGSCAVSAAARLAQHATGRNRVLSSGYHGWHDWHLEAVPEAKPKTFE
                     SYATEFHNDLALYRSWLDRHGEEIAAVVVTPEPHRFDHAYYQELREVAKEHGCLFVVDE
                     VKTGFRAGAGGFSALAGIEPDAVTVSKGMANGHSISAVVGQRQLTQELSEAHVWSTYQN
                     EQVGFAAALASLDFLERHDVAAVTRRTGEAVRQGVLQLFAEHGLPVGAPGWGPMFELDF
                     DAADEGLAERLEAALLRHGIFCDTGDDFNMMFHTAEHTDELLERFAAALGDL"
     aSDomain        7014..7910
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BAD20756.1_Aminotran_3.1"
                     /evalue="1.60E-46"
                     /label="BAD20756.1_Aminotran_3.1"
                     /locus_tag="BAD20756.1"
                     /protein_end="336"
                     /protein_start="37"
                     /score="150.7"
                     /tool="antismash"
                     /translation="LTRGSGTRVYDLDGNAYLDLTGSFGSVLIGHAEPAVVRAVTDVLS
                     EGNLFYTGASPRRLALAERLLDWFPWSEQAIFYRTGSCAVSAAARLAQHATGRNRVLSS
                     GYHGWHDWHLEAVPEAKPKTFESYATEFHNDLALYRSWLDRHGEEIAAVVVTPEPHRFD
                     HAYYQELREVAKEHGCLFVVDEVKTGFRAGAGGFSALAGIEPDAVTVSKGMANGHSISA
                     VVGQRQLTQELSEAHVWSTYQNEQVGFAAALASLDFLERHDVAAVTRRTGEAVRQGVLQ
                     LFAEHGLPVGAPGWGPMF"
     CDS             8089..9615
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF9"
                     /product="oxidoreductase"
                     /protein_id="BAD20757.1"
                     /transl_table=11
                     /translation="MRIISVQEAATRTFDVCVVGSGASGAITAAVLAERGLSVLILEQG
                     TAIPPGTDHDDVEDPDTWAYARDGEGWSKEGYPWSAMAFGGGTVFYGGISFRYEQRDLD
                     PPPALLGDADYAHWRLRLDELEPHYDWVEDRLGVSGPSHGRVGDYAFPHYARGSLPHTP
                     MGGALARGADALGLTPLSTPMAISGARDRHGPGCAELTPCTGFTCPVNAKADVISRILA
                     RAEGDVSVALDTRAVRFVASAPGRAKRLEVLGGSPRSRRSVHADRFVLAANAIQSAALL
                     LRSADRREPDGMGNSSGQVGRHLAMKNSVYVRGRTQERIVAHQPLRHRYSSVCVLDHLR
                     GAEFPGQLGGIIYEANPWEDPEADRPGAGSLLQLECLLGDRPQARNMVRLARSRDRDGL
                     QRIVMDYRQHPLDGERLDVLQGKAKDVLHAAGAERTESVDSDFATGSTHLHGTLRAGDD
                     PATSVTDRTGRLHDYDNVWSADGATFPFAGNFNPTLTIQANARRIAVGIS"
     CDS             9734..11017
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-183). E-value:
                     2.9e-09. Score: 28.3. Matches aSDomain:
                     nrpspksdomains_BAD20758.1_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     395.1; E-value: 5.3e-120)"
                     /gene_kind="biosynthetic"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF10"
                     /product="aminotransferase"
                     /protein_id="BAD20758.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 5.8e-107,
                     bitscore: 348.6, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.3e-09, bitscore:
                     28.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLQSSRLAVDNGTPVRGKPWPVWPQPTDGTLDALSRVLRSGRWA
                     ISGPYRGVESAERRFARRFADYHRIAHCVPASSGTASLMLALEACGVGAGDEVILPGVT
                     WVASASTVVGVNAVPVFADIDPDTLCLDPDAVEAAITPATKAIVVVHLYAAVADLTRLK
                     EVADRHGIVLIEDCAQAHGAEFEGHKVGTFGAVGTFSMQQSKVLTSGEGGAAITADPVL
                     ARRMEHLRADGRCYRDQAPPSGHMELVETGELMGSNRCISEFQAAVLTEQLGELDRFNA
                     LRRHNAELLDALLTDVGYRPQRSTPGTTARTYYTYVAELPDAELPGADITKVTEALTAE
                     LGFPVAPAYSPLNANPLYDPASRSRFALGPQHEKLIDPARFVLPVSGRLTRRLVTFHHA
                     ALLGDESDMRDIAEAFTKVLQHRAVLAA"
     aSDomain        9833..10282
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BAD20758.1_Aminotran_1_2.1"
                     /evalue="2.90E-09"
                     /label="BAD20758.1_Aminotran_1_2.1"
                     /locus_tag="BAD20758.1"
                     /protein_end="183"
                     /protein_start="33"
                     /score="28.3"
                     /tool="antismash"
                     /translation="ALSRVLRSGRWAISGPYRGVESAERRFARRFADYHRIAHCVPASS
                     GTASLMLALEACGVGAGDEVILPGVTWVASASTVVGVNAVPVFADIDPDTLCLDPDAVE
                     AAITPATKAIVVVHLYAAVADLTRLKEVADRHGIVLIEDCAQAHGA"
     CDS             11059..12231
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DHQ_synthase"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DOIS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183:3-dehydroquinate synthase (Score: 365.5; E-value:
                     4e-111)"
                     /gene_kind="biosynthetic"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF11"
                     /product="2-deoxy-scyllo-inosose synthase"
                     /protein_id="BAD20759.1"
                     /sec_met_domain="DOIS (E-value: 1.8e-173, bitscore: 567.0,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-ADH (E-value: 2.8e-09, bitscore: 26.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.2e-70, bitscore:
                     228.3, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVTTITMDDVQYPYRLGTDCLDGIVTRLGELGASRYLIVSDPRV
                     AELYGQGLRERLAEQAGPAELITHASGEQNKGLPALHDLAEEALRRGADRQSIVVALGG
                     GVTGNIAGLLAALLFRGIRLVHVPTTVVAMLDSVLSLKQAVNAGVGKNLVGTFYQPVEV
                     LADTAMLRTLPVREVRSGMCEVVKNSLAIRPSMIDQLSAGLRPDGRYPDDTMHWIIYES
                     LAAKAQVTAYDKYERGEGLILEYGHTVGHAVEHSSQGAVPHGAAVALGMIAAAQVSHRA
                     GWASAELVDLHRELVAKTGVARRIPSDIPLSAVRHRLSFDNKRGYLPASADTYPMVLLE
                     SPGKVLRSEGTVLTAAPRDLVDAVVDELAEPPRPAAARTDDAATVLGGAG"
     misc_feature    11107..11109
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             12228..13349
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 252.7; E-value: 1e-76)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF12"
                     /product="dehydrogenase"
                     /protein_id="BAD20760.1"
                     /transl_table=11
                     /translation="MSAPVRVGVVGAGFMGGVHAEVVAAHPGARLEAVHDLDPAAARDL
                     AERFRAERAEPSWADLLADPAIDLLIITTPNGLHHRQAAEALRAGKHVLVEKPLGVTPE
                     QVAELVELAGRHDRVLAHGSNFVHSPKFVRARQLVADTEAFGRPHLVRVVFRNSGPEAA
                     WAASKDLAGGGALLDLGCHAVELCRWLLDGADVESVSARLQRVRPPHDAEADRASGTAG
                     TARVALEDQALLVMEFADGAVGQCDVSWVTQGGEQVTAEIIGTKGRVEVDLWTGMGLRA
                     YSDKGYQDVWDPEQGWVHPEWEWIRASGYYHQDGTVIEAVGQGIPLTHGPAEALASARV
                     LATGYRSHAEGRVLRLSGAPVGPGASTTAAGSE"
     CDS             13346..13501
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF13"
                     /product="hypothetical protein"
                     /protein_id="BAD20761.1"
                     /transl_table=11
                     /translation="MTATELGATADTAGLRKTADATGLGMTARGRGRPAAVPRPYLVRT
                     SPMEGP"
     CDS             13498..14754
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 293.7;
                     E-value: 4e-89)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF14"
                     /product="glycosyltransferase"
                     /protein_id="BAD20762.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3.3e-43,
                     bitscore: 137.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEPAKGVLALTPFFLYSEYQDHWDPKFDPMGGMHLLVRALVEEM
                     AGRGVPHRVLTMSPPKVPKDIRIGQRIKVHARRLPVLPIPSDLEGYFGLVGAWAKGSLL
                     WVLRNRKRLRREIGAVHAHCDGSGAAAFYPYLMSRILGVPLVVQIHSSRYLSQHPTTLF
                     ERVTDPIAKWAERHAVRKAAAVLMLTDRARDEMRRKAQLPAERVHRLAYLASDQFKDAD
                     TEARRAELRERYGLDDRPIVLYVGRIAAEKGVEYYIEAAAELTRRGRDCQFVIAGDGPA
                     RPDLEKLIGARGLRDRVTITGFMSHEFIPSMISLGELVVLPSRYEELGIVILECMTMRR
                     PLVAHDVNGVNKLIEDGTTGIVVPPFRTPEMADAVERLLDDPELRERMAENAAPLPAAK
                     YSLSAAGDQLAGIYREIGL"
     CDS             14751..15500
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF15"
                     /product="hypothetical protein"
                     /protein_id="BAD20763.1"
                     /sec_met_domain="PIG-L (E-value: 6e-18, bitscore: 56.5,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLLVSPHPDDIALSFGGWVAAHARGLAAKGWRFDLLTVFGTTL
                     YAPHSPRAVTKEAISTLREREDRDYARRHGLRLTSLRQEDCSCLGMDDEEELIAPEATD
                     PRRAAVRQLIAAALAGADLVVAPLAVGGHVDHRIVRTAVRQSLGATPCLWYEDLPYALE
                     SPVEVPSDHRPWLVDIRGHEAAKRADLALYRSQMTAADTSEVLSYRPDGASVPCERLWS
                     SAGFPQDLAERMALATLAAVTPDKESL"
     CDS             15497..16756
                     /NRPS_PKS="Domain: Aminotran_1_2 (50-177). E-value:
                     9.4e-09. Score: 26.7. Matches aSDomain:
                     nrpspksdomains_BAD20764.1_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     350.4; E-value: 2.1e-106)"
                     /gene_kind="biosynthetic"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF16"
                     /product="aminotransferase"
                     /protein_id="BAD20764.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 4.4e-93,
                     bitscore: 303.0, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4e-09, bitscore:
                     26.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKLALFGGTPVRNEEFYDGPHIGPHDLDRLKSVLDSGNFGGIP
                     FPNTHHTAFADLFTGKLGAPYGLMVSNGTISLSIALRALGVRAGDEVITTGYTWMGTAA
                     AIVHINAVPVLVDIDPTTWCIDPAAVEAAITPRTKVIVPVHLGNQIADLDALRAIADKH
                     GLAILEDTAHGHFAEWRGQCVGTHGDAGSFSFESSKIMTAGEGGFLVARDEDVYQRMMS
                     LANCGRKEPGYDGFAGRTLGWNARASELQAAFMIGQVEQHDALHAKRAASAAKLTAGLA
                     EIGGFTPVGNDDPRITRRQYYEVIYRFDPAAWEGLHRDEVLSAILAEGIELEGDAFYPP
                     VHKSELFAVDAVHWPMIAERYGDRIGPDSVDLPVADRAAADESVWVHHALLTGDDKDLG
                     DILEAVAKVRDNLRELHDAS"
     aSDomain        15647..16027
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_BAD20764.1_Aminotran_1_2.1"
                     /evalue="9.40E-09"
                     /label="BAD20764.1_Aminotran_1_2.1"
                     /locus_tag="BAD20764.1"
                     /protein_end="177"
                     /protein_start="50"
                     /score="26.7"
                     /tool="antismash"
                     /translation="HTAFADLFTGKLGAPYGLMVSNGTISLSIALRALGVRAGDEVITT
                     GYTWMGTAAAIVHINAVPVLVDIDPTTWCIDPAAVEAAITPRTKVIVPVHLGNQIADLD
                     ALRAIADKHGLAILEDTAHGHFA"
     CDS             16915..17772
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF17"
                     /product="hypothetical protein"
                     /protein_id="BAD20765.1"
                     /sec_met_domain="PhyH (E-value: 3.3e-20, bitscore: 63.9,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALAAPPGELTLALTPDDKTLDPASLDRALAILAEHGILVLTGML
                     RTRLTDQLRTAMLDDLPEVLRQQDVPTNFVPGHVQQDPPVRESLLFPDVLLNPVVYQIT
                     HAVLGADARNAVYSGNMNLPGSHEQPVHLDEPHLWPGISHPPYCLCVDVPLIDFTLENG
                     STEYWPGSHVLNPDECYDERGCVLPAELERRRAVAPPVRFPIPVGSVVIRDGRLWHRGV
                     PNLSAAPRPLLAMTHYTEWFDMPPIQLPDTVKSWVDGSDRHTHAHFVAGDVDHLTGDHP
                     FAVR"
     CDS             17798..18856
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 95.1;
                     E-value: 9e-29)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF18"
                     /product="hypothetical protein"
                     /protein_id="BAD20766.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.4e-11, bitscore:
                     32.5, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSQLALRGPELSANLCKPEEDTLRVLVTGGSGNVGVGVVRALNA
                     ARHHVVVASRGYSPALLPEGVRAVRLERTEPDAYTRLVAAEKPDAVIDLTCHDAADAAV
                     TLRACAGVDRVVVVSSVTAAGPATTTPVTEATAAPPLSEYGIDKLAVEETVRAAWADGT
                     SQALLVRLGAVYRLGADLDGQLAEDGCWLAHAAAGAPAVLADDGAARWNLLHADDAGAA
                     LAELLANDRARGVLVHLASRHPLPWRELYERVHHALGRPFNPVSVPAEWAAEQLEDAEF
                     LAETSRWDQVFDLGLLDRLAPSYQERGGPSRVTEVALWLIRQGRVGDAELGAEIQELPA
                     RLAAVRTAPGLV"
     misc_feature    17831..17833
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18982..19815
                     /gene="kmr"
     CDS             18982..19815
                     /codon_start=1
                     /gene="kmr"
                     /gene_functions="resistance (resist) ArmA_Rmt (Score: 157;
                     E-value: 3.5e-48)"
                     /gene_kind="resistance"
                     /product="16S rRNA methylase"
                     /protein_id="BAD20767.1"
                     /transl_table=11
                     /translation="MSQSASDEDPKLTRVVEAVRGGRRYRSVTDQAVRRLARAALAVEG
                     GDVTRATKRTKRGLHEVFGAFMPMTPKYEALLRDVREAVELDDPEAIRTALKPALGAHS
                     STRERLPILTEMYAEVFDRLDTAPATVRDLACGMNPLTVPWMPLPAGTTYLASDIDHRL
                     MDFAGTVLTALGVPNRVEVRDLLTDPDPEPADVTFLFKAVPCLEAQGKGLGWKLLDQIN
                     SPVLVVSFPTKTLGRRSRGMYQTHSAEFARRVAERPWKCDEIEFGDELVYVVTKG"
     misc_feature    19015..19017
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             19898..21142
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 271.3;
                     E-value: 2.6e-82)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF20"
                     /product="glycosyltransferase"
                     /protein_id="BAD20768.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 4.1e-34,
                     bitscore: 108.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLRLTPFYHHDCVDSWPAEFDAVGGMQVQILRMSRALAELGVR
                     QQVLTVGFPGLPRVRRDSENLVVRITRAPLPRLRSRITGLVGLNQAWLAAALTECVKLR
                     RRWPADLIQVHLDGQLWALLAGPVAARLVGVPYTVTVHCSRLAVYQPMSTVDRIQHPLV
                     TAVERWALRRAAGITTLTERTATVLAAELGAAQRVIDVVPDAVDPDRAEAAPAEVERLK
                     KRFGLPQEGGPVIGFVGRIAHEKGWRHAVQAVAELADAGRDFTFLVVGDGPQRADMEAA
                     VAEAGLTDRFVFTGFLPNDEIPAVMTALDVLLMPSVHEELGGSAVEAMLAGTPVAAYGV
                     GGLCDTVGKVTPSLLAAPGQVAELARTVKRVLDDPAPVLAELRAGREWLADEFGVHHAA
                     GLALAHYERVLGKER"
     CDS             21201..22208
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF21"
                     /product="hypothetical protein"
                     /protein_id="BAD20769.1"
                     /transl_table=11
                     /translation="MRQDWQHLDESDVRVRPGRRSSRPRSKNRPEHADARSAMVVGVDR
                     GRWTCVLDSDPESRITAMRARELGRKSAVIGDRVDVIGDLSGKPGTLARMVRVARRDSV
                     LRRTADDTDPYERVVVANAEQLVIVCALAAPQPRAGFIDRALVAAYAGGLRPVLCLTKA
                     DLKGPEDVVSTYAHLDLSIVVTRSDRAPDALREQLAGRVSALVGHSGVGKSTLINILIP
                     QARRVTGEVSAIGKGRHTSTSAVALPLPDGGWAVDTPGIRSFGLAHVTSDDVLDAFPDL
                     SDGAEDCPSGCRHLGAPHDSGCGLERLSEADPARARRLESLRRLLRSHAGIEEE"
     CDS             22243..22641
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF22"
                     /product="hypothetical protein"
                     /protein_id="BAD20770.1"
                     /transl_table=11
                     /translation="MSRLTHISAPEGVAPATAYTHVVMGTGRFVAISGQLALDEDGKLV
                     GEGDAAAQAHQVFENLRRCLTAAGATFDDVVKLTYFVTDMAHMRAIRGARDAFLDPERL
                     PASSAVQVGALVAPEYLMEIEAFAVVAE"
     CDS             complement(22665..23336)
                     /codon_start=1
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF23"
                     /product="hypothetical protein"
                     /protein_id="BAD20771.1"
                     /transl_table=11
                     /translation="MPRSHEINRRVTSAPALSVCDLRRREGSAVRLAAMDEELRTVTER
                     LRAEAGGSKEYERLVATGDLEELAEVLVSPGQPLWTRELAAVLLGVAGDRRAFESLVLL
                     LNHRDAPRCAAAAYALARLGDPRTARAAAALATNELRVAYALHPVRLLTELRAPESAPA
                     LITTLRRRLAPHDPFGKIALACVEGLGALGDPRARPVLTAARAHPRLAAAASAALARLP
                     E"
     misc_feature    complement(23199..23201)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             23589..25370
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095:3-hydroxybutyryl-CoA dehydrogenase (Score: 304.4;
                     E-value: 1.1e-92)"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /note="ORF24"
                     /product="dehydrogenase"
                     /protein_id="BAD20772.1"
                     /transl_table=11
                     /translation="MDAPLNTVAVIGLGTMGTGIAEVLARAGREVIGIDISQAAATRAV
                     TALETSTARAVRRERLTDEERRGILARFRTFTDLQAAADVDLVIEVVPESYEIKQRIVR
                     ELDAVVRPETIIATGTNALSVTRLAAESARPERVLGLHFFNPAPAMKLVEIVSSVLTAP
                     AAVAAVTELAYALGKEPVAVGDRPGFVADGLLFGYLNQAAAMYEAKYASREDIDAAMKL
                     GCGLPMGPLALLDLIGVDTARTVLDAMYAESHDRLHAPAPVLKQLSEAGLTGRKSGRGF
                     YTYAEPGSTEVVRDALTPPEGERSVPSRAVRAVGVAGSGTMASGIAEVFAKAGYDVVLA
                     ARSEEKAQLARARIGKSLARSVEKGRITAESAAETLERITPAGSYEAFADVDLALEAIA
                     EDLDVKQQLFATLDKVCKPGAILATTTSSLPVVACARATSRPRDVIGMHFFNPAPAMKL
                     VEVVRTVLTSDEVHATVREVCAAIRKHPVDCGDRAGFIVNALLFPYLNNAIKMVQEHYA
                     TLDDIDAAMKLGGGYPMGPFELLDVVGLDVSLAIEKVLHREFRDPGLAPAPLLEHLVAA
                     GCLGRKTGRGFREYARR"
ORIGIN
        1 gcatgcgggc acatcggagc tgctgcatcc gcaggcgcgg gctcgggcac aatgcaggag
       61 tggaactgaa cggtgagaaa gtgctgctgc ggcccgtgct cgacagcgat gtgaagaagc
      121 tcgacaagat cgtcagagaa cccgaggtgg ccgcttggtg gtcgaccccc gatgactacg
      181 aggagatgct cgccatcacc ctcgacggcg aggtcatcgg ggcagtgcag tacgaggagg
      241 aggaagaccc cgagttccgc cacgcgggca tcgacatctt cctcacggcg agtcggcacg
      301 gcctcggcct cggcacggac accgtccgca ccgtggcacg ttggctgatc gacgagcggg
      361 gacaccaccg gatcaccatc gacccggcgg tggcgaacgc gggcgcgatc cgcagctaca
      421 gcaaggtggg cttcaagccg gtcggcgtca tgcggtcata cgcccgtgac cacacgagcg
      481 gcgtgtggca ggacgccctg ctgatggacc tgctggccga agagctggtc tgacgggtcg
      541 gcccgtccga ccccggccgc ctgtgcgccc ctgccgcccg ccgggcgcgc aggggccctc
      601 acccgtcgcc gacctcggtg aggccgcccg tccggccgcc gagctgaccg gcgagcgagc
      661 gggcgaccgg cgtgcggaag gcgcgtgcga gttccagaag aaacgattct tcaccagaga
      721 tgttcacgct gtcccagccg tgggagaggg aggcgtcgaa gtccttggcc gcccccgtcc
      781 gcctggcccg cagggccacg tgcaggagac aggccagcgt catcgcgtcg gcggagcgcc
      841 cgtgcagacc cagctgttcc acccggctct tcacggctcc cggcagcgcg ggatggacgt
      901 agccgtgcag ggagaggatc gcgtcccgta tctcgatcat cctgcggtag acggccagtc
      961 ggcgcggcgc gcgcggccac accacctcga cgatccggga gcgccgccgg tggagcgcca
     1021 cgtgcggcac cgcctgcacc agggttcgcc acaggggcca cagcacccac agggtcctga
     1081 tctgtgacgg ctgggagcgc atcgagcccc acaggggcac cagcagggcg gccgcccgca
     1141 ggaagccgtg caggctcatc agcagggaca ggttccgcag gggcggctca ccgatgatca
     1201 gccgtccaag ggccacgcac caatagatcc cgaccagagc cgtgcccgcc ccgaagatcc
     1261 acaggctgag gcggagagaa ggggccgagg cccggcagcc ctgccacaga cacacgtgga
     1321 cgcagaccgt gttggccacg atgtgactgc ccatcaggat ggcccagtac gcgctgagcg
     1381 acgaaggacc gcccgggttg tcgtgctgtt cccgcacctg gtcgagcagg accagggcga
     1441 ggacgaccag cgccaccgac gtgacgagtc cccagcgcca ccagcggtgc tgggccgccg
     1501 ccgtgacgaa gtacagcacg caccccgccg acaacacccc gaagaggttc ctggccagac
     1561 ccacctcgtg cacgctgccc gtgaggtcga gggcggccct gatgacgacc ggcagttgca
     1621 gcgccatggc gaccgcggcc gtcgcgacgg ccagccacag gccgcgctgg gccggactcc
     1681 gggcggcggc gggggcgcgc aacaggacca ccgcccccat ggcggcggca ctgacgtact
     1741 gggccacggt cgccgtatgg gccaagtcag cccccacggg tcgctcccac gccgagtgcc
     1801 tcgccgaggt agtgaagcac gtcgtccgcg tgccgttcac cggcgggctg ttcgcccctg
     1861 gtgcggatca ggctggccag catctcggcc tcctgctccc gccgggtggt gtagtcggtg
     1921 cgggcgagca gccgttggat cagctgcggg ctgaggtccc cgaagagctg gggcgcatcg
     1981 ccccagccct cgcccagttc gagcgattga tgaccgaaga gcatgtggcc gatctcgtgc
     2041 aggatgatgt ggtcctgatg cacgcgggcc gtgcgctgct cgaagaagat gtggtcgtcg
     2101 atgtccgtgg ccagccacaa tccgcacgcg cccgcctggg ccgcctgccg cggcaaggcg
     2161 tgcagatgaa ggggccgctg acgctgggcc gcgaggcgcg tacagaagga ttcgacggtg
     2221 aaggggtgcg gcaggctgag tccgtccacg atcgcctggc aacgctgtcg gagtttcaca
     2281 tatatataag acatatgctc tttccgtagg ccttgagcgg ggcatcggta gtaggcggtc
     2341 ctgcggacat gcattgaccc tcccgatcgc gaggacaggg tgctgcgggg tgcccgtggg
     2401 atgcgctcga ttcactccgt gtgctgggga ccgcgcccgt cttcgtcagc cggtggggac
     2461 aggttctgga tcttccgggc ctcgttcacc atgaccagca acgcgtccaa ggtggagggc
     2521 gaaaggcctt ccgcccgaag cgcgagattg cgaatccggt tgtccctgag ggccgttgcc
     2581 agtgcgagtt gagcgtttac ccgttcggac acctcgtcat tgaggaagta ctcaggcggt
     2641 accccgaaat agtctgccag gacaccgagt tgttccagcg tgacgtttcg tttcttgccg
     2701 gtggccaatt cccataggta cgttcccgag atggtcccgc cggtggtttc tcttatgtcc
     2761 tgcgcgagcc gcgcataacc gggccgggtg cccttgtccg gatagatggc gcaaatgaga
     2821 tctttgatgc gctggtcgag tttatccagc agcagcctgc cgctttcgga acgctccgcc
     2881 gcgccgtccc tcatgcgcca ccctctccct gcccggaacg aaggatgaga ccctcgccgt
     2941 agtggacggc tgtcaccgta cgccgtcgcc cagcacgtga ccatggcgcc cgtgatattc
     3001 cggccacgct gtgaccagca ctgtccaact gttcgctata gcggacacgt tgacggtctt
     3061 tcatcagctg gctactgtcg tcaccggttg aacgcccggg tccgcccggc gcggcgcacg
     3121 gcgggtaccg ccgtgatggc ccgcgtgacg cgttcggccg ttagcagcgc gccagacgag
     3181 aacctgatcc cccgccgtgc cgaccggccc ggaccagcag gctccgtcct cccccgctcc
     3241 ctatcgcttc ggcgtcactt caccgtccat tcgtgccgcc ttcggctgcg ccgataaggc
     3301 cgcccgcagc gcaccgccac aatggatttt cggctcctca cagagaaggg cccagccttg
     3361 gcacagcagg ttcacggtag cgcgcccgcc acggtgcgcg agagtgatat ccaggccgcc
     3421 tcgcttcccc cggaaagcaa gtccgagcta ttccagcgga gttcggtgcg cgttccgctc
     3481 gacctgctcc tgcccgcggt gtccccccgc atcgcaggcg tggacgaacg gcacgtccgg
     3541 tcgctcgccg ggatcgaggc cccgctgccg cccatcgtgg tgcaccgcgc cacgctgcgg
     3601 gtgatcgacg ggacgcaccg gctgctcgcc gcccgcgccc ggggggagac ggacgtggag
     3661 gtgcagttct tcgacggcgg tgaggccgat gccttcgtcc tcgccgtcgc cctcaacaac
     3721 gcccaggggc tggcgctctc cccggccgat cgcagtacgg cggcggcgcg catcatcgcc
     3781 tcccatccgc actggtcgga ccgccgcatc gcccgcgtca ccggcctggc cgccagcaca
     3841 gtgggcggtg tccgcaggcg ttcgaccgct cgaaccgcac agccgaacgc gcgcctcggc
     3901 atggacggcc gcatccgccc gcaggacatc gcccaacggc gcaggctggc cgggcagttc
     3961 ctcgccgagc agccgggggc ctccctgcgg accgtggcga aggccgccgg gatctccttg
     4021 agcacggccc acgacgtacg gacgcgactg cgggcgggcg acgatccgct gccccccgcg
     4081 ctgtccaggc cgacgcggcc gcccgccgcg ccggacagcg cggccgacgc cgcggaccgg
     4141 cccgccaagc cgtcctccgc acgctccccg cgaagccccg ggcgcgcccc cgtcgccgcc
     4201 gatctcctgg accggctgcg caaggacccc tcgctgaggt tcacggagga cggccggatc
     4261 cttcttcact ggctcggcgc cgccgtgctc cgcgaacacg gcgccgcacg gttcgcccgc
     4321 tgcgtaccgc cgcacaggac cgccgccatg gcggccctcg cccgcagctg tgcggagggc
     4381 tggctccgtc tcgccgaatc cctcgaccag cgcggcaggt ccgacgcgtg acccggcggg
     4441 agcaggccgg gtccttcccc cgatcacccc tcgtgctccg cccactccgg agcacccgtg
     4501 cacagcgttc aaaggagcag acaccgtgaa ggcactcgtg ttccacagcc ccgagaaggc
     4561 gaccttcgaa cagcgcgacg tccccactcc ccggccgggc gaagccctcg tccacatcgc
     4621 gtacaactcc atctgcggca gcgacctctc gctctaccgc ggtgtctggc acggcttcgg
     4681 ctaccccgtc gtgcccggac acgagtggag cggcaccgtg gtcgagatca acggcgccaa
     4741 cggacacgac cagtcgctgg tcggcaagaa cgtggtgggc gatctgacct gcgcgtgcgg
     4801 gaactgcgcg gcctgcgggc gcgggacccc ggtgctctgc gagaacctcc aggaactcgg
     4861 cttcaccaag gacggcgcct gcgccgagta catgaccatc ccggtcgaca acctccgccc
     4921 gctgccggac gcgctgtcgc tgcgtagcgc ctgccaggtc gaaccgctcg cggtggcgct
     4981 caacgcggtc agcatcgcgg gcgtcgctcc cggtgaccgg gtcgccgtca tgggggccgg
     5041 gggcatcggc ctcatgctga tgcaggtcgc gaggcatctc ggcggtgagg tgacggtcgt
     5101 gtccgaaccg gtcgccgaac ggcgcgcggt cgccgggcag ttgggcgcca ccgagctgtg
     5161 ctccgccgag ccggggcagc tggccgaact cgtcgcccgg cgccccgagc tcacgcccga
     5221 cgtggtcctg gaggcatccg gctatccggc tgcgctccag gaggccatcg aggtggtcag
     5281 gccgggcggc cgcatcggcc tgatcggcta ccgggtggag gagacgggac cgatgtcccc
     5341 gcagcacatc gcggtcaagg cgctgaccct gcgcggctcg ctgggccccg gcggccgctt
     5401 cgacgacgcc gtcgaactgc tcgcgaaggg cgacgacatc gcggtcgagc cgctgctcag
     5461 ccacgagttc ggcctcgccg actacgccac cgcgctcgac ctggcgctgt cccgcacgaa
     5521 cggcaacgtg cgctccttct tcaacctgcg cgactagggc ctgtccggca ccacgacgca
     5581 ccacaacgca ccgcgccaca ccgcacgcac cgctccgcct tcaccgtcgt cgcaccgttc
     5641 gtgaggagac cagggatgag cgtgtcacgg ggccaacgtg ccaacgcgac ggccatacgt
     5701 ctgtggacgt tcatggggtt gatggagctc gttccgctct tcccgctcta tcccctgctc
     5761 ttctccgacc acggattgtc gggatcggcg atctcctcgc tgctcgtcct gtggtcgatg
     5821 accacgttcg tcctggagat cccctcgggc gcgctcggcg acctgctgtc ccgcaggctg
     5881 ctgctcgcgt tcagcgtgct gctgcgggcg ggcgggttca gcctctggtt catcgcaccc
     5941 ggctactggt ccttcgccgt cggattcctg tgctggggag tctgtgacgc cctgacctcc
     6001 ggcaccctgg agtccctcgt ctacgacgaa ctccaggacc gcggcgaagg acatgcctac
     6061 ggccccgtca tgggcaccgg gcgggccatc tcgctgctcg ccacgctcac cgcactgctc
     6121 ctggccgggc cgctcttcgt cctcggcggg tacggtctgg tcggcgcggt cagcgtcggt
     6181 gcgggcgtgg cggccaccat caccgcactg accttcccca atccaccgcg ccacgagatc
     6241 gaatccgaac gcggcggctt ccaccgctat ctcgccacct tcaaagccgg gttcggggag
     6301 gtccgcaggg aacgggccgt catgcggctg gtgttgatcg ccgcgatcct gcagagcatg
     6361 acggccatcg acgagtactt tccgctgctc gcccacgaga acggcgcggc caagagcctc
     6421 atcccggtcc tggtggcgat ccccgtgctg tgcgcctcgg tgggcagctg gatcgcgggc
     6481 cgctccaccg gcgtctcgcg caggaccgcg ttcctcaccg tggcggcgac cgggccgctg
     6541 ctgctcctcg gcgcccagag ccaccaccag tgggggatgc tctcgatcgc cgtggccttc
     6601 ggcatcatcc agtggggcat cgtggtgtcc gggctctggc tccaggacgc catcgtcgga
     6661 tcggcccgcg cgaccatcac ctccgtcgcg ggattcggcg ccgaggtctc ctcggtcggc
     6721 tggtacctgg ccgcggccac cgccctcacg gtcaccgacg tctccggcct cacgtcgtgg
     6781 ttcagcctcc cctgcctcct gatcgcgggc ctcacctggt tctggttccc ggagcgaccg
     6841 gcatccgagc cgaccgaacc gaccgaaccg cagcccacca cctactcgaa gaggtaatca
     6901 ctgtgtccac gcaccccgtc ctggactgga gccgatccgc cgaacacctg cgccgctccc
     6961 acggcgtcac caccgacccc cgccccgacg aggacggcca ctacccctgc gtactgaccc
     7021 ggggcagcgg cactcgcgtg tacgacctgg acggcaacgc ctacctcgat ctcaccggat
     7081 ccttcggctc ggtgctcatc gggcacgcgg aaccggccgt cgtacgggcg gtgaccgacg
     7141 tcctgagcga aggcaatctc ttctacaccg gcgcgagccc gcgccgactg gccctcgcgg
     7201 agcggctcct tgactggttc ccctggtccg agcaggccat cttctaccgc acggggtcct
     7261 gcgcggtgtc cgcggcggcc cggctcgccc agcacgcgac cggccgcaac cgggtgctga
     7321 gttccggcta ccacggctgg cacgactggc acctggaggc ggtgcccgag gccaagccca
     7381 agaccttcga gtcgtacgcc accgagttcc acaacgacct ggcgctctac cgctcctggc
     7441 tcgaccggca cggcgaggag atcgcggcgg tcgtggtgac gcccgagccg caccgcttcg
     7501 accacgccta ctaccaggag ctgcgcgagg tggccaagga gcacggctgc ctgttcgtcg
     7561 tggacgaggt caagaccggc ttccgggccg gggcgggcgg gttcagcgcc ctggccggga
     7621 tcgagccgga cgccgtgacc gtctccaagg gcatggccaa cggacacagc atctccgccg
     7681 tggtgggcca gcgacagctc acccaggagc tgagcgaggc gcacgtctgg tccacctacc
     7741 agaacgaaca ggtggggttc gccgccgcgt tggcgtccct ggacttcctg gagcggcacg
     7801 acgtggcggc cgtgacgcgc cgcacgggtg aggcggtccg gcagggcgtg ctccagctct
     7861 tcgccgaaca cggcctgccc gtcggggcgc cgggctgggg accgatgttc gagctggact
     7921 tcgacgccgc cgacgagggt ctcgccgagc ggctcgaagc ggcgctgctg cgccacggga
     7981 tcttctgcga cacgggcgac gacttcaaca tgatgttcca taccgcggag cacaccgacg
     8041 agctcctcga gcggttcgcc gccgcgctcg gcgacctctg aggccgcggt gcgcatcatc
     8101 tccgtacagg aggcggccac ccgcaccttc gacgtctgcg tggtgggcag cggcgcctcc
     8161 ggtgccatca ccgccgcggt gctcgccgaa cggggcctgt ccgtgctcat cctcgaacag
     8221 ggcaccgcga tcccgccggg caccgaccac gacgacgtcg aggaccccga cacctgggcg
     8281 tacgcacgcg acggggaagg ctggagcaag gagggctatc cctggagcgc catggcgttc
     8341 ggcggcggca cggtgttcta cggcggcatc tccttccgct acgaacagcg cgacctcgac
     8401 ccgccgcccg cgctcctcgg cgacgccgac tacgcgcact ggcggctgcg gctcgacgaa
     8461 ctggagccgc actacgactg ggtggaggac cggctcggcg tgagcggccc gtcccacggc
     8521 cgggtgggcg actacgcctt cccccactac gcgcggggct cgctgccgca caccccgatg
     8581 ggcggcgcgc tggcccgggg cgccgacgcc ctggggctga ccccgctgtc caccccgatg
     8641 gcgatcagcg gggccaggga ccggcacggc cccggctgcg ccgagctgac gccgtgcacc
     8701 ggcttcacct gcccggtcaa cgccaaggcc gatgtgatca gccgcatcct ggcgcgcgcc
     8761 gagggggacg tgtccgtcgc cctggacacc agagcggtgc ggttcgtggc ctcggcaccg
     8821 gggcgggcga aacgtctcga agtgctcggc ggcagtcccc gcagccgccg ctcggtccat
     8881 gccgaccgct tcgtcctcgc ggccaacgcc atccagtccg ccgcgctcct gctgcgttcg
     8941 gcggaccggc gcgagccgga cggcatgggg aactccagcg gtcaggtggg ccgccacctg
     9001 gccatgaaga acagcgtcta cgtccgcggc aggacccagg agcggatcgt cgcccaccag
     9061 ccgctgcgcc atcgctactc cagcgtctgc gtcctggacc acctgcgcgg tgcggagttc
     9121 cccgggcagc tgggcgggat catctacgag gccaacccgt gggaggaccc cgaggccgac
     9181 cgtcctggcg ccggttcgct gctccagctg gagtgcctcc tcggcgaccg cccgcaggcc
     9241 cgcaacatgg tgcggctcgc caggagccgg gaccgggacg ggctccagcg catcgtcatg
     9301 gactaccgcc agcacccctt ggacggcgaa cgcctggacg tgctccaggg gaaggcgaag
     9361 gatgtactgc acgcggccgg ggccgagcgc accgagtccg tcgacagcga tttcgcgacc
     9421 ggcagcacgc atctgcacgg cacgctgcgc gccggtgacg accccgcgac ctcggtgacc
     9481 gaccggacgg gccggctgca cgactacgac aacgtgtggt cggcggacgg cgcgacgttc
     9541 cccttcgccg ggaacttcaa tcccaccctc accatccagg ccaatgcccg gcggatcgcg
     9601 gtcggcatct cctgacggcc gccccctctc ccctcccccg tacgccctgc cgcccttccc
     9661 cgtggcgagc cacccccttc gtgaatcccc cttcgtgacg cgcgaactgt cttcgacctt
     9721 ggaggtatgt gtcatgcccc tgcaaagttc acggcttgcg gtcgacaacg gaacccccgt
     9781 ccgcggcaag ccctggccgg tgtggccgca gcccaccgac ggcaccctcg acgccctctc
     9841 ccgcgtcctg cgttccggcc gctgggccat cagcggcccc taccggggcg tggagtcggc
     9901 cgaacgccgc ttcgcccgcc ggttcgccga ctaccaccgc atcgcccact gcgtgcccgc
     9961 ctccagcggt acggcgagcc tgatgctggc cctggaggcc tgtggcgtcg gcgcgggaga
    10021 cgaggtcatc ctgcccggcg tcacctgggt cgcctccgcc tccacggtgg tgggcgtcaa
    10081 cgcggtgccg gtgttcgccg acatcgaccc ggacaccctc tgcctcgacc cggacgccgt
    10141 cgaggcggcc atcaccccgg ccaccaaggc gatcgtcgtc gtccacctct acgcggccgt
    10201 cgccgacctc acccgcctca aggaggtggc cgaccggcac ggcatcgtgc tcatcgagga
    10261 ctgcgcgcag gcccacggcg ccgagttcga aggccacaag gtcggcacct tcggcgcggt
    10321 cggcaccttc agcatgcagc agagcaaggt cctgaccagc ggcgagggcg gcgccgccat
    10381 caccgccgac ccggtgctcg cccgccggat ggaacacctg cgcgcggacg gccgctgcta
    10441 ccgcgatcag gcgccgccct ccggccacat ggagctcgtc gagacgggcg agctgatggg
    10501 cagcaaccgc tgcatctccg agttccaggc agcggtcctg accgagcagc tgggcgaact
    10561 cgaccggttc aacgccctgc gacggcacaa cgcggaactc ctcgacgcgc tgctgaccga
    10621 cgtcggatac cgcccgcagc gcagcacgcc cggcaccacc gcccgcacgt actacaccta
    10681 cgtcgccgag ctgcccgacg cggaactgcc cggcgcggac atcaccaagg tcaccgaggc
    10741 gctgaccgcc gaactcggct tcccggtggc accggcctac tcgccgctca acgccaaccc
    10801 cctgtacgac ccggccagtc gcagccggtt cgccctcgga ccgcagcacg agaagctcat
    10861 cgaccccgcc cgattcgtgc tcccggtgag cggccgcctg acgcgtcggc tcgtcacctt
    10921 ccaccacgcc gccctgctcg gcgacgagtc ggacatgagg gacatcgcgg aagcgttcac
    10981 caaggtgctc cagcaccggg ccgtcctggc cgcttgagcc gaagccgtca cacacgcctt
    11041 caggattggg gacagaccat gcaggtcacc accatcacga tggatgacgt ccagtatccc
    11101 taccgattag gcacggactg cctcgacggc atcgtcacgc gcctcggcga actcggcgcc
    11161 agccgctacc tgatcgtcag cgaccccagg gtcgccgagc tgtacgggca ggggctgcgc
    11221 gaacggctcg cggagcaggc gggacccgcc gagctgatca cccatgcctc gggagaacag
    11281 aacaagggcc tgcccgcact gcacgacctg gccgaggagg cgctgcggcg cggcgccgac
    11341 cggcagagca tcgtcgtagc actcggcggc ggtgtcaccg ggaacatcgc ggggctgctg
    11401 gccgcgctgc tcttccgcgg catccgtctg gtgcacgtgc ccaccaccgt ggtggccatg
    11461 ctggattcgg tgctctcgct caagcaggcc gtgaacgcgg gagtcggcaa gaacctggtc
    11521 ggcaccttct accagcccgt cgaagtgctc gccgacaccg cgatgctgcg caccctgccg
    11581 gtccgcgagg tcaggtcggg gatgtgcgag gtggtgaaga actcgctcgc catccgcccc
    11641 agcatgatcg accagctgtc ggccgggctg cgccccgacg gccgctatcc cgacgacacg
    11701 atgcactgga tcatctacga gagcctggcc gccaaggccc aggtcacggc gtacgacaag
    11761 tacgagcgcg gcgagggact catcctggag tacgggcaca ccgtcgggca cgccgtggag
    11821 cactcctcgc agggagccgt gccgcacggc gccgccgtcg cgctcggcat gatcgccgcc
    11881 gcccaggtct cccaccgggc gggctgggcc tcggccgaac tcgtcgacct gcaccgggag
    11941 ctcgtcgcca agaccggggt cgcgcggcgc atcccgtccg acataccgct ctccgccgtc
    12001 aggcaccgcc tctccttcga caacaagcgg ggctacctcc cggcctccgc cgacacctat
    12061 ccgatggtgc tgctcgaatc ccccggcaag gtgctgcgca gcgagggcac cgtcctgacg
    12121 gcggcgccac gggacctggt cgacgcggtg gtcgacgaac tcgcggaacc cccacggccc
    12181 gcggccgcga ggaccgacga cgccgccacc gtcctcggcg gtgccgggtg agcgcccccg
    12241 tgcgcgtcgg cgtcgtcggt gcggggttca tgggcggggt gcacgccgag gtggtggcgg
    12301 ctcatcccgg cgcccggctc gaagcggtgc acgacctcga ccccgccgcc gccagggacc
    12361 tggccgagcg gttccgcgcc gagcgggccg agccctcctg ggcggacctg ctcgccgacc
    12421 ccgcgatcga cctgctcatc atcaccacgc ccaacgggct gcaccaccgg caggcggccg
    12481 aggcgctgcg ggcgggcaag cacgtactgg tggagaagcc gctcggtgtc acgccggagc
    12541 aggtggccga gctcgtcgaa ctcgccggac ggcacgaccg ggtccttgcc cacggaagca
    12601 acttcgtgca cagcccgaag ttcgtccggg cccgtcaact ggtcgcggac accgaggcgt
    12661 tcggacggcc gcacctggtc cgggtcgtct tccgcaactc gggccccgag gccgcctggg
    12721 ccgcgtccaa ggacctcgcg ggcggcggag ccctcctgga cctgggctgt cacgcggtgg
    12781 agctgtgccg gtggctgctc gacggcgccg acgtcgagtc ggtcagcgcc cgactgcagc
    12841 gggtgcggcc gccccacgac gccgaagcgg accgcgcgtc cggcaccgcg ggaaccgcgc
    12901 gggtcgcgct ggaggaccag gcgctgctgg tcatggagtt cgccgacggc gcggtcgggc
    12961 agtgcgacgt ctcctgggtc acccagggcg gtgagcaggt caccgcggag atcatcggca
    13021 ccaagggcag ggtcgaggtc gacctgtgga ccggcatggg gctgcgcgcc tactcggaca
    13081 agggctatca ggacgtctgg gatcccgagc agggctgggt gcatccggaa tgggagtgga
    13141 tccgggcgag cggctactac caccaggacg gcaccgtgat cgaggcggtg ggccagggca
    13201 tccccctcac ccacggcccc gcggaagcgc tcgcctcggc ccgtgtcctg gccaccggtt
    13261 accgcagtca cgcggagggg cgggtactgc ggctgtccgg cgcgccggtc ggccctggcg
    13321 cgtcgacgac ggcggcgggc tcggaatgac cgccaccgag ctcggggcga ccgccgacac
    13381 cgccgggctc cggaagaccg ccgacgccac cgggctcggg atgaccgccc ggggccgcgg
    13441 ccgacccgcc gcggtgcctc gtccgtacct cgtccgcacc tcaccgatgg agggaccatg
    13501 accgagcctg ccaagggtgt gctcgcgctg actccgttct ttctgtactc ggagtaccag
    13561 gaccactggg atcccaagtt cgaccccatg ggcggcatgc acctgctggt gcgggccctg
    13621 gtcgaggaga tggcgggccg cggcgtcccg caccgggtcc tgacgatgtc accgcccaag
    13681 gtgcccaagg acatcaggat cgggcagcgg atcaaggtgc acgcccggcg gctgcccgtg
    13741 ctgcccatcc cctccgacct ggaggggtac ttcggactcg tcggcgcctg ggccaagggc
    13801 agcctgttgt gggtgctgcg caaccgcaag cggctgcgcc gggagatcgg cgcggtgcac
    13861 gcgcactgcg acggctcggg cgccgcggcc ttctacccgt atctgatgtc ccggatcctc
    13921 ggcgtgccgc tggtggtcca gatccactcc agccgctatc tgagccagca ccccaccacg
    13981 ctcttcgagc gggtgaccga cccgatcgcc aagtgggcgg agcggcacgc cgtccgcaag
    14041 gccgccgcgg tcctgatgct caccgaccgg gcccgcgacg agatgcggcg caaggcccag
    14101 ctgcccgcgg agcgcgtgca ccggctcgcg tacctggcca gcgaccagtt caaggacgcc
    14161 gacaccgagg cgaggcgggc ggaactgcgg gagcgctacg gcctcgacga ccgcccgatc
    14221 gtgctctacg tggggcggat cgccgccgag aagggcgtgg agtactacat cgaggccgcg
    14281 gccgaactga cccgcagggg ccgggactgc cagttcgtca tcgccgggga cggtcccgcc
    14341 cggccggacc tcgaaaagct gatcggcgcc cgcgggctgc gcgaccgggt gaccatcacg
    14401 ggcttcatgt cccacgagtt catcccatcc atgatctccc tgggcgaact cgtggtgctg
    14461 ccgtcccggt acgaggagct gggcatcgtc atcctggagt gcatgaccat gcgcaggccg
    14521 ctggtcgcgc acgacgtgaa cggcgtcaac aagctcatcg aggacggcac caccggaatc
    14581 gtcgtacccc cgttcaggac cccggagatg gccgacgccg tcgagcggct cctcgacgat
    14641 ccggagctgc gcgagcggat ggcggagaac gccgccccgc tgcccgccgc caagtactcg
    14701 ctctccgcgg cgggcgacca actggcgggc atctaccggg agatcgggct gtgagggtcc
    14761 tcctcgtctc cccccacccc gacgacatcg cgctgtcctt cggcggctgg gtcgcggccc
    14821 acgcccgcgg gctcgcggcc aagggctggc ggttcgacct gctgaccgtc ttcggcacga
    14881 ccctgtacgc gccccacagc ccgcgcgccg tcaccaagga ggccatcagc acgctccggg
    14941 agcgcgagga ccgcgactac gcgcgccgtc acgggctgcg gctgacctct ctccggcagg
    15001 aggactgctc ctgcctgggc atggacgacg aggaggagct catcgccccc gaggcgaccg
    15061 atcctcgccg ggccgccgtg cggcagctga tcgcggcggc gctcgccggg gccgacctgg
    15121 tcgtcgcgcc gctggctgtc ggcggccacg tggatcaccg catcgtccgc accgcggtgc
    15181 ggcagtcgct cggcgccacc ccctgcctct ggtacgagga cctgccgtac gcgttggaga
    15241 gccccgtcga ggtgccctcc gaccaccggc cctggctggt cgacatcagg gggcacgagg
    15301 cggccaagcg cgccgatctc gcgctgtacc gctcgcagat gaccgccgcc gacacctccg
    15361 aggtcctctc gtaccggccg gacggcgcgt ccgtcccgtg cgagcggctc tggagttcgg
    15421 cgggcttccc ccaggacctg gccgagcgga tggcactggc cacgctggcc gccgtgacac
    15481 ccgacaagga gtcgctatga gcaagaagct ggcgctgttc ggcggaactc ccgtacggaa
    15541 cgaggagttc tacgacggcc cgcacatcgg gccgcacgat ctcgaccgcc tcaaatccgt
    15601 cctcgactcg gggaacttcg gcggcatccc cttccccaac acccaccaca ccgccttcgc
    15661 cgacctgttc accggcaagc tcggcgcccc gtacggcctg atggtctcca acggcaccat
    15721 cagtctctcc atcgcgctgc gcgccctggg cgtgcgtgcc ggggacgagg tgatcaccac
    15781 cggctacacc tggatgggca cggccgcggc gatcgtgcac atcaacgccg tccccgtcct
    15841 ggtggacatc gaccccacga cctggtgcat cgacccggcg gcggtggagg cggcgatcac
    15901 cccgcgcacc aaggtgatcg tcccggtcca tctgggcaat cagatcgccg acctcgacgc
    15961 gctgcgggcg atcgccgaca agcacggact cgcgatcctg gaggacaccg cgcacgggca
    16021 cttcgccgag tggcgggggc agtgcgtggg cacccacggg gacgcgggca gcttcagctt
    16081 cgagagcagc aagatcatga ctgccggtga gggcggcttc ctggtggcca gggacgagga
    16141 cgtgtaccag cggatgatgt cgctggccaa ctgcggccgc aaggagccgg gttacgacgg
    16201 tttcgcgggc cgcaccctgg gctggaacgc ccgcgcgagc gaactgcagg ccgccttcat
    16261 gatcgggcag gtcgagcagc acgacgcgct gcacgccaag cgggcggcga gcgcggcgaa
    16321 gctcaccgcg gggctcgccg agatcggcgg cttcactccc gtggggaacg acgacccgag
    16381 gatcacccgg cgccagtact acgaggtcat ctaccgcttc gaccccgccg cctgggaggg
    16441 gctgcaccgg gacgaggtcc tctcggcgat ccttgccgag ggcatcgagc tggagggcga
    16501 cgccttctac ccgcccgtac acaagagcga actgttcgcg gtggacgccg tccactggcc
    16561 catgatcgcc gagaggtacg gcgatcggat cggcccggac agcgtcgacc tgcccgtcgc
    16621 cgaccgcgcc gccgccgacg agtccgtgtg ggtgcaccac gcgctgctca ccggcgacga
    16681 caaggacctc ggcgacatcc tcgaagccgt cgccaaggtc cgcgacaacc tgcgagaact
    16741 gcacgacgcg agctgacctg acggaccccg caggggcggc ggtgtgccgc gccgcgcccc
    16801 cgggtgtgcc ccgtcccgcc caccccgggc gtgccccgtc gcgcccaccc cgcccccggc
    16861 gtctcgtcac cccctccccc cccctcatca gcccctgaga agggaagacc agccatggcc
    16921 cttgccgctc cgcccggcga actgaccctc gccctcacac cggacgacaa gaccctcgat
    16981 cccgcctcgc tcgaccgcgc gctcgccata ctcgccgagc acggcatcct ggtgctgacc
    17041 gggatgctca ggacccggct caccgatcag ctgcgcacgg cgatgctcga cgacctgccc
    17101 gaggtgctgc ggcagcagga cgtgcccacg aacttcgtgc caggacacgt ccaacaggac
    17161 ccgccggtac gggagtcgtt gctcttcccc gacgtgctgc tcaacccggt ggtctaccag
    17221 atcacccatg ccgtgctcgg cgcggacgcc cgcaacgccg tctacagcgg caacatgaac
    17281 ctgccgggca gccacgagca gccggtccac ctggacgagc cgcacctgtg gccgggcatc
    17341 agccaccccc cgtactgcct ctgcgtcgac gtccccctga tcgacttcac gctggagaac
    17401 ggcagcaccg agtactggcc cggctcccac gtcctcaacc ccgacgagtg ctacgacgag
    17461 cggggctgtg tgctgcccgc cgagctggag cggcgccggg ccgtcgcgcc gccggtccgc
    17521 ttccccatcc ccgtcggctc ggtcgtcatc cgcgacggca ggctgtggca ccgcggcgta
    17581 cccaatctga gcgcggcccc ccggcccctg ctggcgatga cccactacac agagtggttc
    17641 gacatgccgc cgatccagct gcccgacacc gtcaagtcct gggtcgacgg ctccgatcgg
    17701 cacacccacg cgcacttcgt ggcgggcgac gtggatcacc tgacgggtga tcatcccttc
    17761 gccgtccgct gacgacgacg gcggccgacg gcgcgccgtg agcagtcaac tcgctctgcg
    17821 ggggcccgag ttatcggcca atctttgcaa acctgaggag gacactttgc gggttcttgt
    17881 caccggaggc tccggcaacg tcggtgtggg tgtcgtcagg gcactcaacg ccgcccgcca
    17941 tcacgtcgtg gtggccagcc gcggctacag ccccgcgctc ctgcccgaag gcgtacgcgc
    18001 cgtacgcctg gagcgcaccg agcccgacgc ctacaccagg ctggtcgccg ccgaaaagcc
    18061 cgacgccgtg atcgatctga cctgccacga cgccgcggac gcggcggtca ccctgcgggc
    18121 ctgcgccggg gtcgaccgcg tcgtggtcgt ctcctcggtg acggccgccg ggcccgccac
    18181 caccactccg gtcaccgagg cgacagcggc accgccgctc tccgagtacg gcatcgacaa
    18241 gctggccgtc gaggagacgg tgcgcgccgc ctgggcggac ggcacctccc aggccctgct
    18301 cgtgcgcctg ggcgcggtct accggctcgg cgcggatctg gacggccaac tcgccgagga
    18361 cggctgctgg ctggcgcacg cggcggccgg agcgcctgcc gtgctcgccg acgacggcgc
    18421 ggcgcggtgg aacctgctgc acgccgacga cgcgggcgcc gcactcgccg aactgctggc
    18481 caacgaccgc gctcgcggcg tcctggtcca cctggcctcc cggcatccgc tgccctggcg
    18541 cgagctgtac gagcgggtcc accacgcgct cggacgcccc ttcaacccgg tttccgtacc
    18601 cgcggagtgg gccgccgagc agctggagga cgccgagttc ctcgccgaga cctcccgctg
    18661 ggaccaggtc ttcgacctcg gcctgctcga ccggctcgcg ccgtcctacc aggagcgcgg
    18721 cggaccgtcg cgcgtcaccg aggtcgccct gtggctgatc cgccaggggc gcgtcgggga
    18781 cgcggaactc ggcgcggaga tacaggagtt gcccgcgcgc ctcgcggccg tgcgcaccgc
    18841 gccagggctg gtatgatttc ggccgatgtg atcgttccgc atgatcccgg cttccgaaga
    18901 tcagttacgt tcctcgtcac gggaggggcg ggctcaccgt ccgccccgac cggcgcgttc
    18961 accccatgga gaggatggcc catgtcgcag tccgcgtccg acgaggaccc caagttaacg
    19021 cgagtcgtgg aggcggtccg gggcggcagg cggtatcgga gcgtgaccga ccaggccgtt
    19081 cgccgactgg ccagagcggc actcgctgtg gagggcggcg acgtcaccag ggccaccaag
    19141 cggaccaagc gcggactcca cgaggtcttc ggcgccttca tgccgatgac gcccaagtac
    19201 gaggcgctgc tgcgcgatgt gcgggaggcc gtcgagctcg atgacccgga ggcgatccgc
    19261 accgccctga aacccgccct cggcgcccac tcctccacca gggagcggct ccccatcctc
    19321 acggaaatgt acgccgaggt cttcgaccgc ctcgacaccg cccccgccac cgtgcgcgac
    19381 ctggcctgcg ggatgaaccc gctgaccgtc ccctggatgc cgctgcccgc cgggacgacc
    19441 tacctcgcct ccgacatcga ccaccgtctg atggacttcg cgggaacggt gctcaccgct
    19501 ctcggagtcc ccaaccgggt agaggtgcgg gacctgttga cggacccgga tcccgaaccg
    19561 gccgacgtca ccttcctgtt caaggccgtc ccctgccttg aggcacaggg caagggcctc
    19621 ggctggaagc tgctcgacca gatcaattcc cccgtcctgg tggtgagttt ccccaccaag
    19681 accctgggcc gccgctccag gggcatgtac cagacccatt ccgcggaatt cgcccggcgc
    19741 gtcgccgaac ggccctggaa gtgcgacgag atcgagttcg gcgacgaact cgtctacgtg
    19801 gtcacgaagg gctgacgacg ggcaggagcc gttcccacga ggcgagggcg ccggaccaga
    19861 acccattggg ctgaactagg caagatggag gtacagcgtg cgcgtactcc ggctcacccc
    19921 gttctaccac cacgactgtg tggacagctg gcccgccgag ttcgacgcgg tgggcggcat
    19981 gcaggtacag atcctgcgga tgtcccgcgc cctggccgag ttgggggtgc gccagcaggt
    20041 gctcaccgtc ggcttccccg gtctgcccag agtgcggcgc gactccgaga acctggtggt
    20101 gcggatcacc agggccccgc tgcccaggct gcgctccagg atcaccggcc tggtcggcct
    20161 caaccaggcg tggctggccg ccgcgctcac cgaatgcgtg aaactgcggc gccgctggcc
    20221 cgccgacctg atccaggtcc atctggacgg ccagctctgg gcgttgctcg cgggaccggt
    20281 cgccgcccgc ctggtgggcg tgccgtacac ggtcaccgtg cactgctcgc ggctggcggt
    20341 gtatcagccc atgtccaccg tcgaccgcat ccagcacccc ttggtgaccg ccgtcgagcg
    20401 ctgggcgctg cgccgtgcgg ccgggatcac cacgctgacc gagcggaccg ccacggtgct
    20461 cgccgccgaa ctgggcgcgg cccagagggt gatcgacgtg gtgcccgacg cggtcgaccc
    20521 cgatcgggcc gaggccgcgc ccgccgaggt cgagcggctg aagaagcgtt tcggcctgcc
    20581 gcaggagggc ggtcccgtca tcggattcgt cggccggatc gcccacgaga agggctggcg
    20641 ccacgccgtc caggcggtgg ccgaactcgc ggacgcgggc cgggacttca ccttcctcgt
    20701 cgtcggagac ggaccgcagc gggccgacat ggaggcggcg gtggccgagg ccggtctcac
    20761 cgaccggttc gtcttcaccg ggttcctgcc caacgacgag atccccgccg tgatgaccgc
    20821 cctggacgtc ctcctgatgc cgtccgtgca cgaggagttg ggcggcagcg ccgtcgaggc
    20881 catgctcgcg ggaacgccgg tggccgccta cggggtcggc ggcctgtgcg acaccgtggg
    20941 caaggtgacc ccgtccttgc tggccgcgcc cggccaggtg gccgaactcg cgcggacggt
    21001 caagcgggta ctcgacgatc ccgcgccggt cctggccgaa ttgcgtgccg gacgggagtg
    21061 gctcgcggac gagttcggtg tccaccacgc ggccggtctc gcgttggccc actatgagcg
    21121 ggtactcggc aaagaacggt agccgtacga cacccgacgt cctgttcgac ttgttctacg
    21181 acagctgatc tggagtatgc gtgaggcagg actggcagca cttggacgag tccgacgtac
    21241 gggtccgacc gggacggcgt agttcccgcc cgcgcagcaa gaaccgcccc gagcacgccg
    21301 acgcccggtc cgccatggtg gtcggggtcg atcgcggccg gtggacctgc gtcctggact
    21361 ccgaccccga gagccggatc accgcgatgc gcgcccgcga actgggccgc aagtcggcgg
    21421 tgataggcga ccgcgtcgac gtgatcggcg acctgtccgg caagccgggc accctggccc
    21481 gcatggtccg ggtcgcccgg cgcgacagcg tcctgcggcg caccgccgac gacacggacc
    21541 cctacgagcg ggtggtggtc gccaacgcgg aacagctggt gatcgtctgc gcgttggcgg
    21601 cgccgcagcc gcgcgccggt ttcatcgacc gtgccctggt ggcggcctac gcgggcggtc
    21661 tgcggccggt gctctgcctg accaaggcgg acctgaaggg ccccgaggac gtggtgagca
    21721 cctacgccca tctggatctg tcgatcgtgg tcacgcgctc cgaccgcgcc ccggacgccc
    21781 tgcgcgagca gctggccggg cgcgtctcgg ccctggtcgg acactccgga gtcggcaagt
    21841 ccacgctgat caacatcctg atcccgcagg cccggcgggt caccggtgaa gtgagcgcga
    21901 tcgggaaggg ccgccacacg tccacctcgg ccgtcgccct gccgctgccg gacggcggct
    21961 gggccgtgga cacccccggc atccgctcct tcgggcttgc ccacgtcacg tccgacgacg
    22021 tcctcgacgc cttccccgac ctgagcgacg gcgcggagga ctgcccgtcc ggctgccgtc
    22081 atctgggcgc cccgcacgac tcgggatgcg gcctggagcg cctgagcgaa gccgatccgg
    22141 ccagggcgcg gcggctggag tcgctgcgcc gcctgctgcg ctcgcacgcg ggcatcgaag
    22201 aggagtgacc accgtgacca cctcgtggtc caccatgggg acatgagccg actgacccac
    22261 atcagcgccc ccgagggcgt cgcccccgcc accgcctaca cccacgtcgt gatgggcacg
    22321 ggccgattcg tcgcgatatc cggccagttg gccctggacg aggacggcaa gctggtcggc
    22381 gagggcgacg cggcggcgca ggcccaccag gtcttcgaga acctgcggcg ctgcctgacc
    22441 gcggcgggcg cgacgttcga cgacgtcgtg aagctgacgt acttcgtgac ggacatggcg
    22501 cacatgcggg cgatccgcgg cgcgcgggac gccttccttg accccgagcg gctgcccgct
    22561 tcctcggcgg tgcaggtggg cgcgctggtc gcgcccgagt atctgatgga gatcgaggcg
    22621 ttcgcggtgg tggccgagta ggcgcgcgcc gaccgccccc gacctcactc cggcagccgc
    22681 gccagggccg ccgaggccgc cgccgcgagg cggggatggg cccgcgccgc ggtcagcacc
    22741 ggtctcgccc gggggtcccc gagcgcgccc aggccctcca cacaggcgag cgcgatcttg
    22801 ccgaacgggt cgtgcggggc gaggcgccgc cgcagcgtcg tgatcagcgc gggcgccgac
    22861 tccggggcgc gcagctccgt caggaggcgc accgggtgca gggcgtaggc gacgcggagt
    22921 tcgttcgtcg ccagggcggc cgccgcgcgc gcggtgcggg ggtcgccgag cctggccagg
    22981 gcgtacgccg ccgccgcgca gcgcggcgcg tcccggtggt tgaggagcag gacgagcgat
    23041 tcgaaggccc ggcggtcccc ggcgacgccg agcaggaccg ccgccaactc ccttgtccac
    23101 aagggctgtc ccggcgagac gagcacctcg gcgagctcct cgaggtcacc ggtcgcgacc
    23161 agccgctcgt actccttcga gccccccgcc tcggcgcgta aacgttccgt caccgtccgc
    23221 aactcctcat ccatggccgc gagcctaacc gccgatccct cccggcgacg tagatcacaa
    23281 acactgaggg ctggcgcgct cgttactcgc cggttaatct catgtgagcg gggcacactc
    23341 cccgtagcac ctccctttcc cgcggtggcc tggtgacgca gccactgtgg gcagcttgtc
    23401 ggttcggtac ttcaggtacc gctgcaccac ctcgtacgac gtggctccgg gacagagccc
    23461 gtcggcttct caccgggcgt gcccttcgcg ccgcccggac acgacacgca ccactttccg
    23521 cacgccgtac ggcagttgcc gcctgcgcgt gcgcccctca gtcgtcactc tcttcctgga
    23581 gtccacgcat ggacgctccc ttgaacaccg tcgccgtcat cggtctgggc acgatgggca
    23641 ccggcatcgc cgaggtcctg gcccgcgcgg gccgcgaggt catcggcatc gacatcagcc
    23701 aggcggcggc cacccgggcg gtgacggccc tggagacctc cacggcccgc gcggtgcggc
    23761 gcgagcgcct caccgatgag gagcggcgcg gcatcctggc ccgcttccgc accttcaccg
    23821 atctgcaggc cgcggccgac gtcgacctgg tgatcgaggt cgtccccgag tcgtacgaga
    23881 tcaagcagcg gatcgtgcgt gaactcgacg ccgtggtccg ccccgagacg atcatcgcga
    23941 ccggcaccaa cgcgctgtcc gtcacccggc tcgccgccga gtcggcgcgc cccgagcgcg
    24001 tgctcggcct gcacttcttc aaccccgcgc ccgcgatgaa gctcgtcgag atcgtctcgt
    24061 ccgtgctcac cgcgcccgcc gccgtcgccg cggtcaccga gctcgcgtac gccctgggca
    24121 aggagcccgt cgcggtcggc gaccggcccg gcttcgtcgc cgacgggctg ctcttcggct
    24181 acctcaacca ggccgccgcg atgtacgagg cgaagtacgc ctcccgcgag gacatcgacg
    24241 ccgcgatgaa gctgggctgc ggcctgccga tgggcccgct cgcgctgctc gacctgatcg
    24301 gcgtggacac cgcccgcacg gtcctcgacg ccatgtacgc cgagtcccac gaccgcctgc
    24361 acgcccccgc gccggtcctc aagcagctca gcgaggcggg cctgaccggg cgcaagtcgg
    24421 ggcgcggctt ctacacgtac gccgagccgg gcagcacgga ggtggtgcgc gacgcgctga
    24481 ccccgccgga gggcgagcgg agcgtcccga gccgtgccgt gcgcgcggtc ggtgtggcgg
    24541 gctccggcac gatggcgtcc ggcatcgccg aggtcttcgc caaggcgggc tacgacgtgg
    24601 tgctcgccgc acgcagcgag gagaaggcgc agctcgccag ggcccgtatc ggcaagtccc
    24661 tcgcgcgctc ggtggagaag gggcggatca ccgccgagtc ggcggcggag accctggagc
    24721 ggatcacccc ggccggttcg tacgaggcgt tcgccgatgt cgatctggcc ctggaggcca
    24781 tcgcggagga cctggacgtc aagcagcagc tgttcgcgac gctcgacaag gtctgcaagc
    24841 ccggcgcgat cctggcgacc acgacgtcct cgctgccggt cgtcgcctgc gcccgcgcca
    24901 cctcgcgccc gcgtgacgtg atcggcatgc acttcttcaa cccggccccg gcgatgaagc
    24961 tggtcgaggt ggtgcgcacc gtgctgacct cggacgaggt gcacgccacc gtccgtgagg
    25021 tctgcgcggc gatccgcaag cacccggtgg actgcggcga ccgcgcgggc ttcatcgtga
    25081 acgcgctgct cttcccgtac ctgaacaacg cgatcaagat ggtccaggag cactacgcca
    25141 cgctggacga catcgacgcc gcgatgaagc tgggcggcgg ctaccccatg gggcccttcg
    25201 agctcctcga cgtggtcggc ctcgatgtct cgctcgccat cgagaaggtc ctgcaccgcg
    25261 agttccgcga cccgggcctg gccccggcgc cgctgctcga acacctggtg gccgcgggct
    25321 gcctcggccg caagacgggg cgtggcttcc gcgaatatgc ccggcgctga gccggccgag
    25381 gaccgcctgg actccgcgac ggactggggc gggctgctcg aaccctcggg cggccctctc
    25441 ccacacgagc accgtgctgc gcatatg
//
