BGC0000703: kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus
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Location: 1,695,607 - 1,729,284 nt. (total: 33,678 nt).
This entry is originally from NCBI GenBank CP023699.1.

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core biosynthetic genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000703
Short description kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (None)
Loci
CP023699.1
1695607 - 1729284
via
Compounds
  • kanamycin
Species Streptomyces kanamyceticus [taxonomy]
References
Chemical products information
kanamycin Evidence:
Copy SMILES
C18H36N4O11
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CP970_06595
  • QEU90618.1
1695608 - 1698106 (-) PAS domain-containing protein
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    • CP970_06600
    • QEU90619.1
    1698248 - 1700683 (-) MFS transporter
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      • CP970_06605
      • QEU90620.1
      1700887 - 1701330 (-) SRPBCC family protein
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        • CP970_06610
        • QEU90621.1
        1701452 - 1702699 (-) arsenic transporter
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          • CP970_06615
          • QEU90622.1
          1702765 - 1702959 (-) antitoxin
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            • CP970_06620
            • QEU90623.1
            • aac_6__
            1703052 - 1703525 (+) aminoglycoside 6'-N-acetyltransferase
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              • CP970_06625
              • QEU90624.1
              1703591 - 1704757 (-) hypothetical protein
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                • CP970_06630
                • QEU90625.1
                1704759 - 1705286 (-) hypothetical protein
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                  • CP970_06635
                  • QEU97141.1
                  1705404 - 1705847 (-) hypothetical protein
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                    • CP970_06640
                    • QEU90626.1
                    1706314 - 1707423 (+) streptomycin biosynthesis protein
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                      • CP970_06645
                      • QEU90627.1
                      1707362 - 1708549 (+) hypothetical protein
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                        • CP970_06650
                        • QEU90628.1
                        1708648 - 1709889 (+) MFS transporter
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                          • CP970_06655
                          • QEU90629.1
                          1709442 - 1711073 (+) aminotransferase class III-fold pyridoxal phosphate-dependent enzyme
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                            • CP970_06660
                            • QEU90630.1
                            1711081 - 1712607 (+) GMC family oxidoreductase
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                              • CP970_06665
                              • QEU90631.1
                              1712726 - 1714009 (+) DegT/DnrJ/EryC1/StrS family aminotransferase
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                                • CP970_06670
                                • QEU90632.1
                                1714051 - 1715223 (+) iron-containing alcohol dehydrogenase
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                                  • CP970_06675
                                  • QEU90633.1
                                  1715220 - 1716341 (+) gfo/Idh/MocA family oxidoreductase
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                                    • CP970_06680
                                    • QEU90634.1
                                    1716490 - 1717746 (+) glycosyltransferase family 1 protein
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                                      • CP970_06685
                                      • QEU90635.1
                                      1717743 - 1718492 (+) PIG-L family deacetylase
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                                        • CP970_06690
                                        • QEU90636.1
                                        1718489 - 1719748 (+) DegT/DnrJ/EryC1/StrS family aminotransferase
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                                          • CP970_06695
                                          • QEU90637.1
                                          1719907 - 1720764 (+) hypothetical protein
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                                            • CP970_06700
                                            • QEU90638.1
                                            1720739 - 1721848 (+) NAD-dependent epimerase/dehydratase family protein
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                                              • CP970_06705
                                              • QEU90639.1
                                              1721974 - 1722807 (+) 16S rRNA methyltransferase
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                                                • CP970_06710
                                                • QEU90640.1
                                                1722890 - 1724134 (+) glycosyltransferase family 1 protein
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                                                  • CP970_06715
                                                  • QEU90641.1
                                                  • rsgA
                                                  1724193 - 1725200 (+) ribosome small subunit-dependent GTPase A
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                                                    • CP970_06720
                                                    • QEU97142.1
                                                    1725235 - 1725633 (+) RidA family protein
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                                                      • CP970_06725
                                                      • QEU90642.1
                                                      1725657 - 1726226 (-) adenylosuccinate lyase
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                                                        • CP970_06730
                                                        • QEU90643.1
                                                        1726581 - 1728362 (+) 3-hydroxyacyl-CoA dehydrogenase
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                                                          • CP970_06735
                                                          • QEU90644.1
                                                          1728349 - 1729284 (+) TetR family transcriptional regulator
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                                                            Biosynthesis information
                                                            Annotation changelog

                                                            Entry version: 3

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            Added new publication with improved reference coordinates
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 2

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            Migrated from v1.4
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                            Entry version: 1

                                                            Date
                                                            Changes
                                                            Submitters
                                                            Reviewers
                                                            Submitted
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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