BGC0000704: kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus
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Location: 1 - 47,050 nt. (total: 47,050 nt).
This entry is originally from NCBI GenBank AJ582817.3.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000704
Short description kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Saccharide
Loci NCBI GenBank: AJ582817.3
Compounds
  • kanamycin
Species Streptomyces kanamyceticus [taxonomy]
References
Chemical products information
kanamycin
Copy SMILES
C18H36N4O11
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAF60509.1
  • kanT
1 - 1014 (+) putative dehydrogenase
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  • CAF60511.1
  • kacT
1132 - 2106 (+) conserved hypothetical protein
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  • CAF60512.1
  • kanS
2111 - 3220 (+) putative ABC transporter sugar binding protein
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  • CAF60513.1
  • kanR
3217 - 4782 (+) putative sugar ABC-transproter ATP-binding protein
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  • CAF60514.1
  • kanQ
4791 - 6032 (+) putative sugar ABC-transproter transport permease
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  • CAF60515.1
  • kanP
6252 - 7226 (-) putative O-methyltransferase
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  • CAF60516.1
  • kacS
7552 - 8388 (+) putative NAD synthase
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  • CAF60518.1
  • kacR
8454 - 8882 (-) hypothetical protein
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  • CAF60519.1
  • kacQ
8990 - 9712 (-) hypothetical protein
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  • CAF60520.1
  • kacP
9907 - 12405 (-) conserved hypothetical protein
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  • CAF60521.1
  • kanO
12547 - 14982 (-) putative efflux protein
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  • CAF60522.1
  • kacO
15186 - 15629 (-) conserved hypothetical protein
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  • CAF60524.1
  • kanN
15751 - 17013 (-) putative membrane efflux protein
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  • CAF60525.1
  • kanM
17378 - 17824 (+) kanamycin 6-acetyl transferase
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  • CAF60526.1
  • kacN
17890 - 19131 (-) hypothetical protein
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  • CAF60528.1
  • kacM
19703 - 20275 (-) hypothetical protein
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  • CAF60529.1
  • kanL
20613 - 21722 (+) putative transcriptional regulatory protein
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  • CAF60530.1
  • kanK
21817 - 22848 (+) GntP-like protein
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  • CAF60532.1
  • kanJ
22947 - 24188 (+) putative transport protein
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  • CAF60533.1
  • kacL
24194 - 25372 (+) GntJ-like protein
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  • CAF60534.1
  • kanI
25380 - 26906 (+) GntX like protein
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  • CAE46938.1
  • kanB
27025 - 28308 (+) putative glutamine--scyllo-inosose aminotransferase
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  • CAE46939.1
  • kanA
28350 - 29522 (+) 2-deoxy-scyllo-inosose synthase
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  • CAE46940.1
  • kanC
29674 - 30753 (+) putative dehydrogenase kanC
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  • CAE46941.1
  • kanE
31001 - 32161 (+) putative glycosyl transferase kanE
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  • CAE46942.1
  • kacA
32158 - 32907 (+) hypothetical protein
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  • CAE46943.1
  • kanD
32904 - 34163 (+) putative glutamine--scyllo-inosose aminotransferase
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  • CAE46944.1
  • kacB
34322 - 35179 (+) hypothetical protein
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  • CAE46945.1
  • kacC
35667 - 36263 (+) hypothetical protein
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  • CAE46946.1
  • kmr
36389 - 37222 (+) 16s ribosomal RNA methylase
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  • CAE46947.1
  • kanF
37386 - 38549 (+) putative glycosyltransferase
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  • CAE46948.1
  • kacD
38722 - 39615 (+) putative GTPase
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  • CAE46949.1
  • kacE
39650 - 40048 (+) hypothetical protein
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  • CAE46950.1
  • kacF
40072 - 40641 (-) hypothetical protein
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  • CAE46951.1
  • kacG
40996 - 42777 (+) putative oxidoreductase
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  • CAE46952.2
  • kanG
42890 - 43702 (+) putative regulatory protein
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  • CAE46953.1
  • kacH
43821 - 45410 (+) putative crotonyl-CoA reductase
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  • CAE46954.1
  • kacI
45417 - 45983 (+) hypothetical protein
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  • CAE46955.1
  • kacJ
46006 - 46428 (-) hypothetical protein
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  • CAE46956.1
  • kacK
46679 - 47050 (-) hypothetical protein
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
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