BGC0000704: kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus
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Location: 1 - 47,050 nt. (total: 47,050 nt).
This entry is originally from NCBI GenBank AJ582817.3.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000704
Short description kanamycin biosynthetic gene cluster from Streptomyces kanamyceticus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (None)
Loci
AJ582817.3
via
Compounds
  • kanamycin
Species Streptomyces kanamyceticus [taxonomy]
References
Chemical products information
kanamycin Evidence:
Copy SMILES
C18H36N4O11
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAF60509.1
  • kanT
 1 - 1014 (+) putative dehydrogenase
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    • CAF60511.1
    • kacT
    		 1132 - 2106 (+) conserved hypothetical protein
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      • CAF60512.1
      • kanS
      		 2111 - 3220 (+) putative ABC transporter sugar binding protein
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        • CAF60513.1
        • kanR
        		 3217 - 4782 (+) putative sugar ABC-transproter ATP-binding protein
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          • CAF60514.1
          • kanQ
          		 4791 - 6032 (+) putative sugar ABC-transproter transport permease
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            • CAF60515.1
            • kanP
            		 6252 - 7226 (-) putative O-methyltransferase
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              • CAF60516.1
              • kacS
              		 7552 - 8388 (+) putative NAD synthase
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                • CAF60518.1
                • kacR
                		 8454 - 8882 (-) hypothetical protein
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                  • CAF60519.1
                  • kacQ
                  		 8990 - 9712 (-) hypothetical protein
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                    • CAF60520.1
                    • kacP
                    		 9907 - 12405 (-) conserved hypothetical protein
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                      • CAF60521.1
                      • kanO
                      		 12547 - 14982 (-) putative efflux protein
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                        • CAF60522.1
                        • kacO
                        		 15186 - 15629 (-) conserved hypothetical protein
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                          • CAF60524.1
                          • kanN
                          		 15751 - 17013 (-) putative membrane efflux protein
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                            • CAF60525.1
                            • kanM
                            		 17378 - 17824 (+) kanamycin 6-acetyl transferase
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                              • CAF60526.1
                              • kacN
                              		 17890 - 19131 (-) hypothetical protein
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                                • CAF60528.1
                                • kacM
                                		 19703 - 20275 (-) hypothetical protein
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                                  • CAF60529.1
                                  • kanL
                                  		 20613 - 21722 (+) putative transcriptional regulatory protein
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                                    • CAF60530.1
                                    • kanK
                                    		 21817 - 22848 (+) GntP-like protein
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                                      • CAF60532.1
                                      • kanJ
                                      		 22947 - 24188 (+) putative transport protein
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                                        • CAF60533.1
                                        • kacL
                                        		 24194 - 25372 (+) GntJ-like protein
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                                          • CAF60534.1
                                          • kanI
                                          		 25380 - 26906 (+) GntX like protein
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                                            • CAE46938.1
                                            • kanB
                                            		 27025 - 28308 (+) putative glutamine--scyllo-inosose aminotransferase
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                                              • CAE46939.1
                                              • kanA
                                              		 28350 - 29522 (+) 2-deoxy-scyllo-inosose synthase
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                                                • CAE46940.1
                                                • kanC
                                                		 29674 - 30753 (+) putative dehydrogenase kanC
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                                                  • CAE46941.1
                                                  • kanE
                                                  		 31001 - 32161 (+) putative glycosyl transferase kanE
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                                                    • CAE46942.1
                                                    • kacA
                                                    		 32158 - 32907 (+) hypothetical protein
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                                                      • CAE46943.1
                                                      • kanD
                                                      		 32904 - 34163 (+) putative glutamine--scyllo-inosose aminotransferase
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                                                        • CAE46944.1
                                                        • kacB
                                                        		 34322 - 35179 (+) hypothetical protein
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                                                          • CAE46945.1
                                                          • kacC
                                                          		 35667 - 36263 (+) hypothetical protein
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                                                            • CAE46946.1
                                                            • kmr
                                                            		 36389 - 37222 (+) 16s ribosomal RNA methylase
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                                                              • CAE46947.1
                                                              • kanF
                                                              		 37386 - 38549 (+) putative glycosyltransferase
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                                                                • CAE46948.1
                                                                • kacD
                                                                		 38722 - 39615 (+) putative GTPase
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                                                                  • CAE46949.1
                                                                  • kacE
                                                                  		 39650 - 40048 (+) hypothetical protein
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                                                                    • CAE46950.1
                                                                    • kacF
                                                                    		 40072 - 40641 (-) hypothetical protein
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                                                                      • CAE46951.1
                                                                      • kacG
                                                                      		 40996 - 42777 (+) putative oxidoreductase
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                                                                        • CAE46952.2
                                                                        • kanG
                                                                        		 42890 - 43702 (+) putative regulatory protein
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                                                                          • CAE46953.1
                                                                          • kacH
                                                                          		 43821 - 45410 (+) putative crotonyl-CoA reductase
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                                                                            • CAE46954.1
                                                                            • kacI
                                                                            		 45417 - 45983 (+) hypothetical protein
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                                                                              • CAE46955.1
                                                                              • kacJ
                                                                              		 46006 - 46428 (-) hypothetical protein
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                                                                                • CAE46956.1
                                                                                • kacK
                                                                                		 46679 - 47050 (-) hypothetical protein
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                                                                                  Biosynthesis information
                                                                                  Annotation changelog

                                                                                  Entry version: 2

                                                                                  Date
                                                                                  Changes
                                                                                  Submitters
                                                                                  Reviewers
                                                                                  2019-10-16
                                                                                  Migrated from v1.4
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                                  Entry version: 1

                                                                                  Date
                                                                                  Changes
                                                                                  Submitters
                                                                                  Reviewers
                                                                                  2015-06-12
                                                                                  Submitted
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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