LOCUS       BGC0000705             41576 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptomyces kanamyceticus partial kanamycin biosynthesis gene
            cluster, strain DSM 40500.
ACCESSION   BGC0000705
VERSION     BGC0000705
KEYWORDS    .
SOURCE      Streptomyces kanamyceticus
  ORGANISM  Streptomyces kanamyceticus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:04:46
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 41576
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..41576
                     /db_xref="taxon:1967"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces kanamyceticus"
                     /segment="Genomic regions of the kanamycin biosynthetic
                     gene cluster"
                     /strain="DSM 40500"
                     /type_material="type strain of Streptomyces kanamyceticus"
     subregion       1..41576
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000705"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..41576
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="2dos"
                     /region_number="1"
                     /rules="((DOIS or DHQ_synthase or ValA or salQ) and
                     DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             <1..1555
                     /codon_start=2
                     /db_xref="GOA:Q2MFX3"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="UniProtKB/TrEMBL:Q2MFX3"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 126.8; E-value:
                     1.8e-38)"
                     /gene_kind="transport"
                     /note="ORF SkaJ19.1"
                     /product="putative sugar ABC transporter"
                     /protein_id="CAF31568.1"
                     /transl_table=11
                     /translation="MLEMRAITKTFPGVTALSDVNLTVRPGEIHAICGENGAGKSTLMK
                     VLSGVHPHGSYDGEILFEGEPMAFKDIRASERRGIVIIHQELALVPHLSIAENIFLGNE
                     QARGGFVDWNGTLRRAGALLKRVGLREKPQTPVADIGVGKQQLVEIAKALSKEVRLLIL
                     DEPTAALNDDDSAKLLGLIGELREQGIACIIISHKLNEIRAVTDAVTILRDGRTVETLT
                     VRETPDAEAELSEDRIIRGMVGRDLDHRFPDRTPYAGEDAGTLALSVAGWTVRHPVDQQ
                     RTVVDDVSLTVRRGEIVGIAGLMGAGRTELAMSVFGRSYGVYVAGDVAVNGRPVVTRTV
                     PAAVDAGIAYVTEDRKRYGLNLIDDINRNVSLASLPGMRRRGVVDEHHERSVAERYRKA
                     MNIKAPTVFEEVGRLSGGNQQKVVLSKWIHADPEVLILDEPTRGIDVGAKYEIYTVIDE
                     LAAQGKAVLFISSELPELLGMCDRIYTMAEGRLTGEVTRAEATQEVLMRHMTQTRSPKS
                     "
     regulatory      1547..1551
                     /note="ORF SkaJ19.2"
                     /regulatory_class="ribosome_binding_site"
     CDS             1564..2805
                     /codon_start=1
                     /db_xref="GOA:Q65CE8"
                     /db_xref="InterPro:IPR000914"
                     /db_xref="InterPro:IPR001851"
                     /db_xref="UniProtKB/TrEMBL:Q65CE8"
                     /gene_functions="transport (smcogs)
                     SMCOG1113:inner-membrane translocator (Score: 317.3;
                     E-value: 1.7e-96)"
                     /gene_kind="transport"
                     /note="ORF SkaJ19.2"
                     /product="putative sugar ABC transporter"
                     /protein_id="CAF31569.1"
                     /transl_table=11
                     /translation="MTTTTTPPGSSRDASDAPPPARWPAGALLLRSVRSNTRQYGMLIA
                     LAFLVVLFQIWTDGTLLLPNNVSNLIQQNGYILILAIGMMIVIIAGHIDLSVGSLVAFV
                     GAMSAVMMVKHDMPWVLALVLSLLIGAVAGAWQGFFIAYVGIPSFIVTLAGMLLFRGLT
                     QIVLEGQSLAPFPDGFQNIAKGFIPEMGPYTQYHNPTLVLGLLAVALLLLRERRARKRQ
                     LAYELDVLPTGLWAAKCVAMTAAVVAFTLTLASFHGVPVVMLIMCGLLIALGYVMRNAV
                     IGRHVYALGGNKAAAKLSGVKDKRVTLLVFVNMGVLAALAGCVYAARLNAGTPQAGLNF
                     ELEAIAASFIGGASMSGGVGTVLGAVIGGLVLGVLNNGMSLVGIGTDYQQVIKGLVLLA
                     AVGFDVWNKRKAGR"
     CDS             complement(3025..3999)
                     /codon_start=1
                     /db_xref="GOA:Q65CE6"
                     /db_xref="HSSP:Q06528"
                     /db_xref="InterPro:IPR000051"
                     /db_xref="InterPro:IPR001077"
                     /db_xref="UniProtKB/TrEMBL:Q65CE6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:O-methyltransferase (Score: 322.7; E-value:
                     4.7e-98)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SkaJ19.3c"
                     /product="putative O-methyltransferase"
                     /protein_id="CAF31570.1"
                     /transl_table=11
                     /translation="MAAQTLRAAARMRVVELIGDKERTAAEVAAEAGARPEGMIRLLRA
                     LAGIGVVAERTPGVFAVTPTGALLDSRRPGNVASLVLMMSDPTMLRGWEHLDEVVRTGE
                     PAFDTVFGTDFFGHLREHPEESARFNEAMSQSTGAAAATLPRAFDFTRFATVADVGGGD
                     GTLLSAVLKEHTGLTGIIYDTAEGLAQAPATLERHGLTERCSSVAGDFFQSAPKGADLY
                     LLKSILHDWPDERAVTILSHCRAVLPPEGRVLILEHVLPEAVDPAAPGFAYLSDLNMLV
                     NLGGRERTRADFDELCGRAGLSIVSVTPMGAPNPLSMIEVAAA"
     regulatory      complement(4001..4005)
                     /note="ORF SkaJ19.3c"
                     /regulatory_class="ribosome_binding_site"
     regulatory      4314..4319
                     /note="ORF SkaJ19.4"
                     /regulatory_class="ribosome_binding_site"
     CDS             4325..5161
                     /codon_start=1
                     /db_xref="GOA:Q65CE5"
                     /db_xref="HSSP:P18843"
                     /db_xref="InterPro:IPR003694"
                     /db_xref="UniProtKB/TrEMBL:Q65CE5"
                     /note="ORF SkaJ19.4"
                     /product="putative NH3-dependent NAD(+) synthase"
                     /protein_id="CAF31571.1"
                     /transl_table=11
                     /translation="MTDPASTALQQEIARDLQVSASFDPAREIERRVAFLTERLTSTGL
                     RSLVLGISGGVDSTTAGRLCQLAVERARTAGHEATFYAMRLPYGVQADEKDAQLALGFI
                     AADQVLTVDVKAASDAALEAALTGGVVFRDERHQDFVQGNIKARQRMIAQYAVAGARDG
                     LVVGTDHAAEAVSGFFTKFGDGAADVVPLTGLTKRRVRAVADALGAPAELVWKVPTADL
                     ETLDPGKPDEDALGVTYDEIDDFLEGKPVSDASFRSIVGRYRLTDHKRRLPIAPTA"
     CDS             complement(5227..5655)
                     /codon_start=1
                     /db_xref="InterPro:IPR000897"
                     /db_xref="InterPro:IPR011944"
                     /db_xref="UniProtKB/TrEMBL:Q65CE4"
                     /note="ORF SkaJ19.5c"
                     /product="hypothetical protein"
                     /protein_id="CAF31572.1"
                     /transl_table=11
                     /translation="MTRDEIEVRALLESRADAAQAKDIDRLMPLFAPDVVYFDVVPPMR
                     FAGHGEVRKNFVRWFEGYEGPITLETRELTVAVGDDVAFAHMLHLDSGTRTNGMQSAML
                     VRSTVCCRRVSGTWLITHEHISLPIDPATLQAWMPPQA"
     regulatory      complement(5601..5605)
                     /note="ORF SkaJ19.5c"
                     /regulatory_class="ribosome_binding_site"
     CDS             complement(5763..6485)
                     /codon_start=1
                     /db_xref="GOA:Q65CE3"
                     /db_xref="InterPro:IPR013217"
                     /db_xref="UniProtKB/TrEMBL:Q65CE3"
                     /note="ORF SkaJ19.6c"
                     /product="hypothetical protein"
                     /protein_id="CAF31573.1"
                     /transl_table=11
                     /translation="MSVTSKYRAAWESFWSDAPDEQGAVFWDAEPALTAGLHLALFEPH
                     LAAAGLPIIDLGCGNGTQTRFLADRYPRVLGVDISAAALDHARRADPAGQADFRQLDIA
                     EWSVAEQLHAELGDVNVYMRGVLHQCDPDDRQPLLDNIARLVGERGRAFVVELSEAAKP
                     VLLGLAQSPTGPPPKLAPVFAHGLAPAEVVDEAVREYVAAAGLAVLAEGELPLTTTEFR
                     PDGTRIELPSWWQVLGLD"
     regulatory      complement(6492..6497)
                     /note="ORF SkaJ19.6c"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(6680..9178)
                     /gene="kaoA"
     CDS             complement(6680..9178)
                     /codon_start=1
                     /db_xref="GOA:Q65CE2"
                     /db_xref="HSSP:P23222"
                     /db_xref="InterPro:IPR000014"
                     /db_xref="InterPro:IPR001437"
                     /db_xref="InterPro:IPR001932"
                     /db_xref="InterPro:IPR003018"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="InterPro:IPR010822"
                     /db_xref="InterPro:IPR013767"
                     /db_xref="UniProtKB/TrEMBL:Q65CE2"
                     /gene="kaoA"
                     /gene_functions="other (smcogs) SMCOG1054:hypothetical
                     protein (Score: 408.5; E-value: 6.9e-124)"
                     /gene_kind="other"
                     /note="ORF SkaJ19.7c"
                     /product="possible kanamycin regulatory protein"
                     /protein_id="CAF31574.1"
                     /transl_table=11
                     /translation="MEQGTPGSGPVAQRAMAGRIPLAVVVVDGSGLVSHWSTGARRLFG
                     YAKEDAVGRPVGDLLPVHGAIPDAAGPYGEYDGLGPDLETSLDGRISYPAAGRARLDEP
                     GSDPARRLDVLWWAYPLVGPGPERLLVLAADAAALTDAGRAEDRDEQGEQAELGERDDR
                     AQGATSFRHWGSIAPGFALHTDFPGADRLADGLPEILPSMSVGESSRIVAQVLELGYPV
                     LEFSQHDRVPVTPDWGVARRAERKERRQRAARAAAHGLPAAVTADDEGDDLEYAAVREH
                     LEFLNEVSGRIGSSLDLAQTIVEVSKAVVPRFTDVAGTYLREQVVAGEGFPEGVPDETT
                     MWHRVALEHTDEPGRWDDVVPVGESMPFPVHTPFFQCMTSGDPVLVPRITEEMGNAIAS
                     QFEKRDIRPLINHRSMLVVPLKARNVVLGFMILLRHRERPVFNDMDRVTGSELAARAGL
                     VLDNARMYTYQESVADTLQDSMLPHIDPRMPGGDIATRYLPGTLLGRVGGDWFDSVKLP
                     GSRTALVVGDVMGHGLNSAAMMGQLRTAVQTMAALDLPPEQLLRNLDDLAQRLGEHYLA
                     TCLYAVYDPIASELSLANAGHIPPVLVRAADGRSELLDLPTGAPIGVGGVPFESVRIRV
                     APGDRLLMCTDGLVEVRGEDIGVGLATLTESAAHPAASMDDACDTIIRALNTRGGRKDD
                     VALLMARLNGIAADDVAHWRFETGPGEVSRARELVRAQLREWSLGALADTAELLVSELV
                     TNVVRHSRSERLELRLVRSAVLMCEVEDDDHTLPTLRSAGGDDEFGRGLRVVSALAKEW
                     GTSRTNAGKTVWFELALPRR"
     protocluster    8590..41576
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[18589:41573]"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      18590..>41573
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
     cand_cluster    8590..41576
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /kind="single"
                     /product="2dos"
                     /protoclusters="1"
                     /tool="antismash"
     regulatory      complement(9187..9195)
                     /note="ORF SkaJ19.7c"
                     /regulatory_class="ribosome_binding_site"
     CDS             complement(9320..11755)
                     /codon_start=1
                     /db_xref="GOA:Q65CE1"
                     /db_xref="InterPro:IPR000627"
                     /db_xref="InterPro:IPR001411"
                     /db_xref="InterPro:IPR001958"
                     /db_xref="InterPro:IPR004638"
                     /db_xref="InterPro:IPR007114"
                     /db_xref="InterPro:IPR008454"
                     /db_xref="InterPro:IPR008969"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="UniProtKB/TrEMBL:Q65CE1"
                     /gene="kanZ"
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 530.6; E-value:
                     4.5e-161)"
                     /gene_kind="transport"
                     /note="ORF SkaJ19.8c"
                     /product="putative kanamycin efflux protein"
                     /protein_id="CAF31575.1"
                     /transl_table=11
                     /translation="MGGTTLVKAVERDGTEAVEAADAPPERGAAQAPPPPAPGATAHGL
                     SPRRVRMVFVGLMLALLLAALEQMIVATALPKIVGELHGLDKMSWAITAYLLTSTVGLP
                     IYGKLGDLFGRKGVFQFAIVIFVIGSALAGWSRTMDELIAFRAIQGVGAGGLMIGVQAI
                     IADIVPPRQRGRYMGLIGASFGLASVAGPLLGGFFTDHASWRWCFYFNVPFGLVTLLVV
                     SLVLKLPKPASRGRLDVLGALLLAAASTCLVLLTSWGGTEYAWGDRVILGLGAGAVASA
                     LLFLVAEHFAAEPIIPLRLFRDPVFNITGLVGMVVGIALFGAASYLPTFLQMVDGASAT
                     ESGLLMLPMMGGIVGASVISGQLISHTGRYKIYPVLGGALSVVGMWLLSRLEVDTPRLQ
                     YSIWMAVLGAGIGMVMPVLVLAVQNAVRPADLGTATSANNYFRQIGGSVGAAIFGTLFA
                     NRLADALADRIPADAGAALPDAESITPQLVHALPPALRDGYIEAYADAMPRIFLYLVPV
                     LVLGMLIAFFLKETPLLSSAASQNAPAAEPAPVPQARTSTYTAGVPVCGTVQHPDGTVV
                     PRAALTLIDVAGQQIGRGASGEDGRYALSTPGSGSFVLIAAAGGHQPQAVTVTVGERPV
                     DLDVVLGGAGRLAGTVVTADGTPVRDAAVTLTDVRGEVVATTRSGREGSYVITELVAGE
                     YTLAASAPAFRPAALPVSVQASRETRQDVELAGGAVLRGTVRASGGRPVEDARVTLLDA
                     AGNVVDTLTTGADGTFRFIDLSSGEYTVIAAGYPPVATVLQVAGGGRTERDLQLGHED"
     gene            complement(9320..11769)
                     /gene="kanZ"
     regulatory      complement(11762..11769)
                     /gene="kanZ"
                     /note="ORF SkaJ19.8c"
                     /regulatory_class="ribosome_binding_site"
     CDS             complement(11959..12402)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (3-146). E-value: 2e-22.
                     Score: 72.0. Matches aSDomain:
                     nrpspksdomains_kanY_Polyketide_cyc2.1"
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q65CE0"
                     /function="putative kanamycin production protein"
                     /gene="kanY"
                     /note="ORF SkaJ19.9c"
                     /product="KanY"
                     /protein_id="CAF31576.1"
                     /transl_table=11
                     /translation="MAQVEATTERIIAAQPDDVFDALADYNGTREKILSDHFSEYEVRE
                     GGDGEGTLVHWKLQATSKRIRDCLLEVGEPNDGELVEKDRNSSMVTTWTVTPAGEGKSR
                     VVVSTVWNGAGGIGGFFEKTFAPKGLGRIYDAVLGKLAAEVEK"
     gene            complement(11959..12414)
                     /gene="kanY"
     aSDomain        complement(11965..12393)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_kanY_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="2.00E-22"
                     /label="kanY_Polyketide_cyc2.1"
                     /locus_tag="kanY"
                     /protein_end="146"
                     /protein_start="3"
                     /score="72.0"
                     /tool="antismash"
                     /translation="VEATTERIIAAQPDDVFDALADYNGTREKILSDHFSEYEVREGGD
                     GEGTLVHWKLQATSKRIRDCLLEVGEPNDGELVEKDRNSSMVTTWTVTPAGEGKSRVVV
                     STVWNGAGGIGGFFEKTFAPKGLGRIYDAVLGKLAAEVE"
     regulatory      complement(12407..12414)
                     /gene="kanY"
                     /note="ORF SkaJ19.9c"
                     /regulatory_class="ribosome_binding_site"
     CDS             complement(12524..13786)
                     /codon_start=1
                     /db_xref="GOA:Q65CD9"
                     /db_xref="InterPro:IPR000802"
                     /db_xref="UniProtKB/TrEMBL:Q65CD9"
                     /gene="kanX"
                     /note="ORF SkaJ19.10c"
                     /product="putative integral membrane kanamycin efflux
                     protein"
                     /protein_id="CAF31577.1"
                     /transl_table=11
                     /translation="MHDRIMLVEFLSVAALVVVLVCAVVRPFRWPEAAFAVPAAGVVVL
                     SGAIPLDDVREEAARLGPVIGFLAGVLVLAKLCADEGLFHACGTWMARWAARRPRRLLT
                     AVFGLASVITAALSLDATVVLLTPVVFATAARMGAPPKPHVYASAHLSNTASLLLPVSN
                     LTNLLAFTATGLSFTRFALLMTLPWLVAIAVEYAVFQRFFAAELDAPVDGGDTAEPPEM
                     PLFALVTVVATLAGFAVASAVGIDPAWAAAAGALVLGVRALLRGRTTPVAILRSASLPF
                     LAFVLALGVVVRAVVDNGLGDALGHVLPDGASLPALLGTAAVAGLLANLINNLPAVLAL
                     VPLAAPSGPGAVLAVLIGVNIGPNLTYAGSLATLLWRRIAHQHEHDVDLREFTRLGLLT
                     TPAALVLSTLALWVSLRLLPV"
     gene            complement(12524..13800)
                     /gene="kanX"
     regulatory      complement(13796..13800)
                     /gene="kanX"
                     /note="ORF SkaJ19.10c"
                     /regulatory_class="ribosome_binding_site"
     CDS             complement(13837..14031)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFW3"
                     /gene="kanW"
                     /note="ORF SkaJ19.11c"
                     /product="possible kanamycin biosynthetic protein"
                     /protein_id="CAF31578.1"
                     /transl_table=11
                     /translation="MSVMDKLKQMLKGHEDQAGKGIDKAGDFVDDKTQGKYSSQVDTAQ
                     DKLKEQLGGDQGQDQPPQS"
     gene            complement(13837..14044)
                     /gene="kanW"
     regulatory      complement(14038..14044)
                     /gene="kanW"
                     /note="ORF SkaJ19.11c"
                     /regulatory_class="ribosome_binding_site"
     regulatory      14049..14053
                     /gene="kanA"
                     /note="ORF SkaJ19.12"
                     /regulatory_class="ribosome_binding_site"
     gene            14049..14597
                     /gene="kanA"
     CDS             14067..14597
                     /codon_start=1
                     /db_xref="GOA:Q75PS3"
                     /db_xref="InterPro:IPR000182"
                     /db_xref="UniProtKB/TrEMBL:Q75PS3"
                     /gene="kanA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111:GCN5-related N-acetyltransferase (Score: 61;
                     E-value: 2.2e-18)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SkaJ19.12"
                     /product="kanamycin 6'-acetyltransferase"
                     /protein_id="CAF31579.1"
                     /transl_table=11
                     /translation="MRAHRSCCIRRRGLGHNAGVELNGEKVLLRPVLDSDVKKLDKIVR
                     EPEVAAWWSTPDDYEEMLAITLDGEVIGAVQYEEEEDPEFRHAGIDIFLTASRHGLGLG
                     TDTVRTVARWLIDERGHHRITIDPAVANAGAIRSYSKVGFKPVGVMRSYARDHTSGVWQ
                     DALLMDLLAEELV"
     gene            complement(14663..15784)
                     /gene="kanG"
     CDS             complement(14663..15784)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFW1"
                     /function="possible component of regulator system"
                     /function="putative kanamycin production protein"
                     /gene="kanG"
                     /note="ORF SkaJ19.13c"
                     /product="KanG"
                     /protein_id="CAF31580.1"
                     /transl_table=11
                     /translation="MGAVVLLRAPAAARSPAQRGLWLAVATAAVAMALQLPVVIRAALD
                     LTGSVHEVGLARNLFGVLSAGCVLYFVTAAAQHRWWRWGLVTSVALVVLALVLLDQVRE
                     QHDNPGGPSSLSAYWAILMGSHIVANTVCVHVCLWQGCRASAPSLRLSLWIFGAGTALV
                     GIYWCVALGRLIIGEPPLRNLSLLMSLHGFLRAAALLVPLWGSMRSQPSQIRTLWVLWP
                     LWRTLVQAVPHVALHRRRSRIVEVVWPRAPRRLAVYRRMIEIRDAILSLHGYVHPALPG
                     AVKSRVEQLGLHGRSADAMTLACLLHVALRARRTGAAKDFDASLSHGWDSVNISGEESF
                     LLELARAFRTPVARSLAGQLGGRTGGLTEVGDG"
     CDS             complement(15831..16418)
                     /codon_start=1
                     /db_xref="InterPro:IPR006025"
                     /db_xref="UniProtKB/TrEMBL:Q6L746"
                     /function="putative kanymcin production protein; possible
                     component of regulator system"
                     /gene="kanH"
                     /note="ORF SkaJ19.14c"
                     /product="KanH"
                     /protein_id="CAF31581.1"
                     /transl_table=11
                     /translation="MHVRRTAYYRCPAQGLRKEHMSYIYVKLRQRCQAIVDGLSLPHPF
                     TVESFCTRLAAQRQRPLHLHALPRQAAQAGACGLWLATDIDDHIFFEQRTARVHQDHII
                     LHEIGHMLFGHQSLELGEGWGDAPQLFGDLSPQLIQRLLARTDYTTRREQEAEMLASLI
                     RTRGEQPAGERHADDVLHYLGEALGVGATRGG"
     gene            complement(15831..16428)
                     /gene="kanH"
     regulatory      complement(16423..16428)
                     /gene="kanH"
                     /note="ORF SkaJ19.14c"
                     /regulatory_class="ribosome_binding_site"
     CDS             complement(16476..16958)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFV9"
                     /function="putative kanymcin production protein; possible
                     component of regulator system"
                     /gene="kanI"
                     /note="ORF SkaJ19.15c"
                     /product="KanI"
                     /protein_id="CAF31582.1"
                     /transl_table=11
                     /translation="MRDGAAERSESGRLLLDKLDQRIKDLICAIYPDKGTRPGYARLAQ
                     DIRETTGGTISGTYLWELATGKKRNVTLEQLGVLADYFGVPPEYFLNDEVSERVNAQLA
                     LATALRDNRIRNLALRAEGLSPSTLDALLVMVNEARKIQNLSPPADEDGRGPQHTE"
     gene            complement(16476..16974)
                     /gene="kanI"
     regulatory      complement(16965..16974)
                     /gene="kanI"
                     /note="ORF SkaJ19.15c"
                     /regulatory_class="ribosome_binding_site"
     regulatory      17372..17377
                     /gene="kanR"
                     /note="ORF SkaJ19.16"
                     /regulatory_class="ribosome_binding_site"
     gene            17372..18495
                     /gene="kanR"
     CDS             17386..18495
                     /codon_start=1
                     /db_xref="GOA:Q6L744"
                     /db_xref="InterPro:IPR003115"
                     /db_xref="UniProtKB/TrEMBL:Q6L744"
                     /gene="kanR"
                     /note="ORF SkaJ19.16"
                     /product="putative regulator of gene expression"
                     /protein_id="CAF31583.1"
                     /transl_table=11
                     /translation="MDFRLLTEKGPALAQQVHGSAPATVRESDIQAASLPPESKSELFQ
                     RSSVRVPLDLLLPAVSPRIAGVDERHVRSLAGIEAPLPPIVVHRATLRVIDGTHRLLAA
                     RARGETDVEVQFFDGGEADAFVLAVALNNAQGLALSPADRSTAAARIIASHPHWSDRRI
                     ARVTGLAASTVGGVRRRSTARTAQPNARLGMDGRIRPQDIAQRRRLAGQFLAEQPGASL
                     RTVAKAAGISLSTAHDVRTRLRAGDDPLPPALSRPTRPPAAPDSAADAADRPAKPSSAR
                     SPRSPGRAPVAADLLDRLRKDPSLRFTEDGRILLHWLGAAVLREHGAARFARCVPPHRT
                     AAMAALARSCAEGWLRLAESLDQRGRSDA"
     regulatory      18577..18581
                     /gene="kanE"
                     /note="ORF SkaJ19.17"
                     /regulatory_class="ribosome_binding_site"
     gene            18577..19621
                     /gene="kanE"
     CDS             18590..19621
                     /NRPS_PKS="Domain: PKS_ER (113-261). E-value: 3e-11. Score:
                     34.9. Matches aSDomain: nrpspksdomains_kanE_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GOA:Q6L743"
                     /db_xref="InterPro:IPR002085"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="UniProtKB/Swiss-Prot:Q6L743"
                     /gene="kanE"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADSI-DH"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 328.3; E-value:
                     7.8e-100)"
                     /gene_kind="biosynthetic"
                     /note="ORF SkaJ19.17"
                     /product="3-amino-2,3-dideoxy-scyllo-inositol
                     1-dehydrogenase"
                     /protein_id="CAF31584.1"
                     /sec_met_domain="ADSI-DH (E-value: 7.7e-177, bitscore:
                     578.3, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 1.1e-26, bitscore: 84.1,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.2e-23, bitscore:
                     74.8, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVFHSPEKATFEQRDVPTPRPGEALVHIAYNSICGSDLSLYR
                     GVWHGFGYPVVPGHEWSGTVVEINGANGHDQSLVGKNVVGDLTCACGNCAACGRGTPVL
                     CENLQELGFTKDGACAEYMTIPVDNLRPLPDALSLRSACQVEPLAVALNAVSIAGVAPG
                     DRVAVMGAGGIGLMLMQVARHLGGEVTVVSEPVAERRAVAGQLGATELCSAEPGQLAEL
                     VARRPELTPDVVLEASGYPAALQEAIEVVRPGGRIGLIGYRVEETGPMSPQHIAVKALT
                     LRGSLGPGGRFDDAVELLAKGDDIAVEPLLSHEFGLADYATALDLALSRTNGNVRSFFN
                     LRD"
     aSDomain        18929..19372
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_kanE_PKS_ER.1"
                     /evalue="3.00E-11"
                     /label="kanE_PKS_ER.1"
                     /locus_tag="kanE"
                     /protein_end="261"
                     /protein_start="113"
                     /score="34.9"
                     /tool="antismash"
                     /translation="TKDGACAEYMTIPVDNLRPLPDALSLRSACQVEPLAVALNAVSIA
                     GVAPGDRVAVMGAGGIGLMLMQVARHLGGEVTVVSEPVAERRAVAGQLGATELCSAEPG
                     QLAELVARRPELTPDVVLEASGYPAALQEAIEVVRPGGRIGLIG"
     regulatory      19708..19713
                     /gene="kanT"
                     /note="ORF SkaJ19.18"
                     /regulatory_class="ribosome_binding_site"
     gene            join(19708..19713,19720..20961)
                     /gene="kanT"
     CDS             19720..20961
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q6L742"
                     /gene="kanT"
                     /gene_functions="transport (smcogs) SMCOG1202:major
                     facilitator transporter (Score: 60.5; E-value: 1.8e-18)"
                     /gene_kind="transport"
                     /note="ORF SkaJ19.18"
                     /product="putative kanamycin export protein"
                     /protein_id="CAF31585.1"
                     /transl_table=11
                     /translation="MSVSRGQRANATAIRLWTFMGLMELVPLFPLYPLLFSDHGLSGSA
                     ISSLLVLWSMTTFVLEIPSGALGDLLSRRLLLAFSVLLRAGGFSLWFIAPGYWSFAVGF
                     LCWGVCDALTSGTLESLVYDELQDRGEGHAYGPVMGTGRAISLLATLTALLLAGPLFVL
                     GGYGLVGAVSVGAGVAATITALTFPNPPRHEIESERGGFHRYLATFKAGFGEVRRERAV
                     MRLVLIAAILQSMTAIDEYFPLLAHENGAAKSLIPVLVAIPVLCASVGSWIAGRSTGVS
                     RRTAFLTVAATGPLLLLGAQSHHQWGMLSIAVAFGIIQWGIVVSGLWLQDAIVGSARAT
                     ITSVAGFGAEVSSVGWYLAAATALTVTDVSGLTSWFSLPCLLIAGLTWFWFPERPASEP
                     TEPTEPQPTTYSKR"
     gene            20951..20957
                     /gene="kanB"
     regulatory      20951..20957
                     /gene="kanB"
                     /note="ORF SkaJ19.19"
                     /regulatory_class="ribosome_binding_site"
     gene            20967..22145
                     /gene="kanB"
     CDS             20967..22145
                     /NRPS_PKS="Domain: Aminotran_3 (37-336). E-value: 1.6e-46.
                     Score: 150.7. Matches aSDomain:
                     nrpspksdomains_kanB_Aminotran_3.1"
                     /codon_start=1
                     /db_xref="GOA:Q6L741"
                     /db_xref="HSSP:Q8DLK8"
                     /db_xref="InterPro:IPR005814"
                     /db_xref="UniProtKB/TrEMBL:Q6L741"
                     /gene="kanB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 294.4;
                     E-value: 2.1e-89)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SkaJ19.19"
                     /product="pyridoxalphosphate-dependent aminotransferase
                     class III"
                     /protein_id="CAF31586.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.4e-49, bitscore:
                     158.4, seeds: 13, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.7e-09, bitscore:
                     28.5, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTHPVLDWSRSAEHLRRSHGVTTDPRPDEDGHYPCVLTRGSGTR
                     VYDLDGNAYLDLTGSFGSVLIGHAEPAVVRAVTDVLSEGNLFYTGASPRRLALAERLLD
                     WFPWSEQAIFYRTGSCAVSAAARLAQHATGRNRVLSSGYHGWHDWHLEAVPEAKPKTFE
                     SYATEFHNDLALYRSWLDRHGEEIAAVVVTPEPHRFDHAYYQELREVAKEHGCLFVVDE
                     VKTGFRAGAGGFSALAGIEPDAVTVSKGMANGHSISAVVGQRQLTQELSEAHVWSTYQN
                     EQVGFAAALASLDFLERHDVAAVTRRTGEAVRQGVLQLFAEHGLPVGAPGWGPMFELDF
                     DAADEGLAERLEAALLRHGIFCDTGDDFNMMFHTAEHTDELLERFAAALGDL"
     aSDomain        21078..21974
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_kanB_Aminotran_3.1"
                     /evalue="1.60E-46"
                     /label="kanB_Aminotran_3.1"
                     /locus_tag="kanB"
                     /protein_end="336"
                     /protein_start="37"
                     /score="150.7"
                     /tool="antismash"
                     /translation="LTRGSGTRVYDLDGNAYLDLTGSFGSVLIGHAEPAVVRAVTDVLS
                     EGNLFYTGASPRRLALAERLLDWFPWSEQAIFYRTGSCAVSAAARLAQHATGRNRVLSS
                     GYHGWHDWHLEAVPEAKPKTFESYATEFHNDLALYRSWLDRHGEEIAAVVVTPEPHRFD
                     HAYYQELREVAKEHGCLFVVDEVKTGFRAGAGGFSALAGIEPDAVTVSKGMANGHSISA
                     VVGQRQLTQELSEAHVWSTYQNEQVGFAAALASLDFLERHDVAAVTRRTGEAVRQGVLQ
                     LFAEHGLPVGAPGWGPMF"
     gene            22144..22147
                     /gene="kanD1"
     regulatory      22144..22147
                     /gene="kanD1"
                     /note="ORF SkaJ19.20"
                     /regulatory_class="ribosome_binding_site"
     gene            22153..23679
                     /gene="kanQ"
     CDS             22153..23679
                     /codon_start=1
                     /db_xref="GOA:Q6L740"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="UniProtKB/TrEMBL:Q6L740"
                     /gene="kanQ"
                     /note="ORF SkaJ19.20"
                     /product="oxidoreductase; putative kanamycin
                     6'-dehydrogenase"
                     /protein_id="CAF31587.1"
                     /transl_table=11
                     /translation="MRIISVQEAATRTFDVCVVGSGASGAITAAVLAERGLSVLILEQG
                     TAIPPGTDHDDVEDPDTWAYARDGEGWSKEGYPWSAMAFGGGTVFYGGISFRYEQRDLD
                     PPPALLGDADYAHWRLRLDELEPHYDWVEDRLGVSGPSHGRVGDYAFPHYARGSLPHTP
                     MGGALARGADALGLTPLSTPMAISGARDRHGPGCAELTPCTGFTCPVNAKADVISRILA
                     RAEGDVSVALDTRAVRFVASAPGRAKRLEVLGGSPRSRRSVHADRFVLAANAIQSAALL
                     LRSADRREPDGMGNSSGQVGRHLAMKNSVYVRGRTQERIVAHQPLRHRYSSVCVLDHLR
                     GAEFPGQLGGIIYEANPWEDPEADRPGAGSLLQLECLLGDRPQARNMVRLARSRDRDGL
                     QRIVMDYRQHPLDGERLDVLQGKAKDVLHAAGAERTESVDSDFATGSTHLHGTLRAGDD
                     PATSVTDRTGRLHDYDNVWSADGATFPFAGNFNPTLTIQANARRIAVGIS"
     regulatory      23785..23789
                     /gene="kanS1"
                     /note="ORF SkaJ19.21"
                     /regulatory_class="ribosome_binding_site"
     gene            23785..25081
                     /gene="kanS1"
     CDS             23798..25081
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-183). E-value:
                     2.9e-09. Score: 28.3. Matches aSDomain:
                     nrpspksdomains_kanS1_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GOA:Q6L739"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="UniProtKB/Swiss-Prot:Q6L739"
                     /gene="kanS1"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     395.1; E-value: 5.3e-120)"
                     /gene_kind="biosynthetic"
                     /note="ORF SkaJ19.21"
                     /product="L-glutamine:2-deoxy-ketocyclitol
                     aminotransferase"
                     /protein_id="CAF31588.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 8.7e-107,
                     bitscore: 348.6, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.9e-09, bitscore:
                     28.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLQSSRLAVDNGTPVRGKPWPVWPQPTDGTLDALSRVLRSGRWA
                     ISGPYRGVESAERRFARRFADYHRIAHCVPASSGTASLMLALEACGVGAGDEVILPGVT
                     WVASASTVVGVNAVPVFADIDPDTLCLDPDAVEAAITPATKAIVVVHLYAAVADLTRLK
                     EVADRHGIVLIEDCAQAHGAEFEGHKVGTFGAVGTFSMQQSKVLTSGEGGAAITADPVL
                     ARRMEHLRADGRCYRDQAPPSGHMELVETGELMGSNRCISEFQAAVLTEQLGELDRFNA
                     LRRHNAELLDALLTDVGYRPQRSTPGTTARTYYTYVAELPDAELPGADITKVTEALTAE
                     LGFPVAPAYSPLNANPLYDPASRSRFALGPQHEKLIDPARFVLPVSGRLTRRLVTFHHA
                     ALLGDESDMRDIAEAFTKVLQHRAVLAA"
     aSDomain        23897..24346
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_kanS1_Aminotran_1_2.1"
                     /evalue="2.90E-09"
                     /label="kanS1_Aminotran_1_2.1"
                     /locus_tag="kanS1"
                     /protein_end="183"
                     /protein_start="33"
                     /score="28.3"
                     /tool="antismash"
                     /translation="ALSRVLRSGRWAISGPYRGVESAERRFARRFADYHRIAHCVPASS
                     GTASLMLALEACGVGAGDEVILPGVTWVASASTVVGVNAVPVFADIDPDTLCLDPDAVE
                     AAITPATKAIVVVHLYAAVADLTRLKEVADRHGIVLIEDCAQAHGA"
     regulatory      25112..25116
                     /gene="kanC"
                     /note="ORF SkaJ19.22"
                     /regulatory_class="ribosome_binding_site"
     gene            join(25112..25116,25123..26295)
                     /gene="kanC"
     CDS             25123..26295
                     /codon_start=1
                     /db_xref="GOA:Q6L738"
                     /db_xref="InterPro:IPR002658"
                     /db_xref="UniProtKB/Swiss-Prot:Q6L738"
                     /gene="kanC"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DOIS"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DHQ_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183:3-dehydroquinate synthase (Score: 365.5; E-value:
                     4e-111)"
                     /gene_kind="biosynthetic"
                     /note="ORF SkaJ19.22"
                     /product="2-deoxy scyllo-inosose synthase"
                     /protein_id="CAF31589.1"
                     /sec_met_domain="DOIS (E-value: 2.7e-173, bitscore: 567.0,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-ADH (E-value: 4.2e-09, bitscore: 26.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.8e-70, bitscore:
                     228.3, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVTTITMDDVQYPYRLGTDCLDGIVTRLGELGASRYLIVSDPRV
                     AELYGQGLRERLAEQAGPAELITHASGEQNKGLPALHDLAEEALRRGADRQSIVVALGG
                     GVTGNIAGLLAALLFRGIRLVHVPTTVVAMLDSVLSLKQAVNAGVGKNLVGTFYQPVEV
                     LADTAMLRTLPVREVRSGMCEVVKNSLAIRPSMIDQLSAGLRPDGRYPDDTMHWIIYES
                     LAAKAQVTAYDKYERGEGLILEYGHTVGHAVEHSSQGAVPHGAAVALGMIAAAQVSHRA
                     GWASAELVDLHRELVAKTGVARRIPSDIPLSAVRHRLSFDNKRGYLPASADTYPMVLLE
                     SPGKVLRSEGTVLTAAPRDLVDAVVDELAEPPRPAAARTDDAATVLGGAG"
     misc_feature    25171..25173
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     regulatory      26290..26296
                     /gene="kanD2"
                     /note="ORF SkaJ19.23"
                     /regulatory_class="ribosome_binding_site"
     gene            join(26290..26296,26304..27413)
                     /gene="kanD2"
     CDS             26304..27413
                     /codon_start=1
                     /db_xref="GOA:Q2MFV1"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="UniProtKB/TrEMBL:Q2MFV1"
                     /gene="kanD2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 252.8; E-value: 9.7e-77)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SkaJ19.23"
                     /product="oxidoreductase"
                     /protein_id="CAF31590.1"
                     /transl_table=11
                     /translation="MRVGVVGAGFMGGVHAEVVAAHPGARLEAVHDLDPAAARDLAERF
                     RAERAEPSWADLLADPAIDLLIITTPNGLHHRQAAEALRAGKHVLVEKPLGVTPEQVAE
                     LVELAGRHDRVLAHGSNFVHSPKFVRARQLVADTEAFGRPHLVRVVFRNSGPEAAWAAS
                     KDLAGGGALLDLGCHAVELCRWLLDGADVESVSARLQRVRPPHDAEADRASGTAGTARV
                     ALEDQALLVMEFADGAVGQCDVSWVTQGGEQVTAEIIGTKGRVEVDLWTGMGLRAYSDK
                     GYQDVWDPEQGWVHPEWEWIRASGYYHQDGTVIEAVGQGIPLTHGPAEALASARVLATG
                     YRSHAEGRVLRLSGAPVGPGASTTAAGSE"
     gene            27632..27635
                     /gene="kanM1"
     regulatory      27632..27635
                     /gene="kanM1"
                     /note="ORF SkaJ19.24"
                     /regulatory_class="ribosome_binding_site"
     gene            27652..28818
                     /gene="kanM2"
     CDS             27652..28818
                     /codon_start=1
                     /db_xref="GOA:Q2MFV0"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q2MFV0"
                     /gene="kanM2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 291.4;
                     E-value: 2e-88)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SkaJ19.24"
                     /product="putative paromamine 6-glucosyltransferase"
                     /protein_id="CAF31591.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 4.2e-43,
                     bitscore: 138.2, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGMHLLVRALVEEMAGRGVPHRVLTMSPPKVPKDIRIGQRIKVH
                     ARRLPVLPIPSDLEGYFGLVGAWAKGSLLWVLRNRKRLRREIGAVHAHCDGSGAAAFYP
                     YLMSRILGVPLVVQIHSSRYLSQHPTTLFERVTDPIAKWAERHAVRKAAAVLMLTDRAR
                     DEMRRKAQLPAERVHRLAYLASDQFKDADTEARRAELRERYGLDDRPIVLYVGRIAAEK
                     GVEYYIEAAAELTRRGRDCQFVIAGDGPARPDLEKLIGARGLRDRVTITGFMSHEFIPS
                     MISLGELVVLPSRYEELGIVILECMTMRRPLVAHDVNGVNKLIEDGTTGIVVPPFRTPE
                     MADAVERLLDDPELRERMAENAAPLPAAKYSLSAAGDQLAGIYREIGL"
     gene            28802..28807
                     /gene="kanN"
     regulatory      28802..28807
                     /gene="kanN"
                     /note="ORF SkaJ19.25"
                     /regulatory_class="ribosome_binding_site"
     gene            28815..29564
                     /gene="kanN"
     CDS             28815..29564
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q6L734"
                     /function="putative kanamycin production protein"
                     /gene="kanN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SkaJ19.25"
                     /product="KanN"
                     /protein_id="CAF31592.1"
                     /sec_met_domain="PIG-L (E-value: 9e-18, bitscore: 56.5,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLLVSPHPDDIALSFGGWVAAHARGLAAKGWRFDLLTVFGTTL
                     YAPHSPRAVTKEAISTLREREDRDYARRHGLRLTSLRQEDCSCLGMDDEEELIAPEATD
                     PRRAAVRQLIAAALAGADLVVAPLAVGGHVDHRIVRTAVRQSLGATPCLWYEDLPYALE
                     SPVEVPSDHRPWLVDIRGHEAAKRADLALYRSQMTAADTSEVLSYRPDGASVPCERLWS
                     SAGFPQDLAERMALATLAAVTPDKESL"
     gene            29549..29554
                     /gene="kanS2"
     regulatory      29549..29554
                     /gene="kanS2"
                     /note="ORF SkaJ19.26"
                     /regulatory_class="ribosome_binding_site"
     gene            29561..30820
                     /gene="kanS2"
     CDS             29561..30820
                     /NRPS_PKS="Domain: Aminotran_1_2 (50-177). E-value:
                     9.4e-09. Score: 26.7. Matches aSDomain:
                     nrpspksdomains_kanS2_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GOA:Q6L733"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="UniProtKB/Swiss-Prot:Q6L733"
                     /gene="kanS2"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     350.4; E-value: 2.1e-106)"
                     /gene_kind="biosynthetic"
                     /note="ORF SkaJ19.26"
                     /product="putative pyridoxalphosphate-dependent
                     aminotransferase class IV"
                     /protein_id="CAF31593.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 6.6e-93,
                     bitscore: 303.0, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 6e-09, bitscore:
                     26.7, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKKLALFGGTPVRNEEFYDGPHIGPHDLDRLKSVLDSGNFGGIP
                     FPNTHHTAFADLFTGKLGAPYGLMVSNGTISLSIALRALGVRAGDEVITTGYTWMGTAA
                     AIVHINAVPVLVDIDPTTWCIDPAAVEAAITPRTKVIVPVHLGNQIADLDALRAIADKH
                     GLAILEDTAHGHFAEWRGQCVGTHGDAGSFSFESSKIMTAGEGGFLVARDEDVYQRMMS
                     LANCGRKEPGYDGFAGRTLGWNARASELQAAFMIGQVEQHDALHAKRAASAAKLTAGLA
                     EIGGFTPVGNDDPRITRRQYYEVIYRFDPAAWEGLHRDEVLSAILAEGIELEGDAFYPP
                     VHKSELFAVDAVHWPMIAERYGDRIGPDSVDLPVADRAAADESVWVHHALLTGDDKDLG
                     DILEAVAKVRDNLRELHDAS"
     aSDomain        29711..30091
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_kanS2_Aminotran_1_2.1"
                     /evalue="9.40E-09"
                     /label="kanS2_Aminotran_1_2.1"
                     /locus_tag="kanS2"
                     /protein_end="177"
                     /protein_start="50"
                     /score="26.7"
                     /tool="antismash"
                     /translation="HTAFADLFTGKLGAPYGLMVSNGTISLSIALRALGVRAGDEVITT
                     GYTWMGTAAAIVHINAVPVLVDIDPTTWCIDPAAVEAAITPRTKVIVPVHLGNQIADLD
                     ALRAIADKHGLAILEDTAHGHFA"
     regulatory      30967..30972
                     /note="ORF SkaJ19.27"
                     /regulatory_class="ribosome_binding_site"
     gene            30979..31836
                     /gene="kanJ"
     CDS             30979..31836
                     /codon_start=1
                     /db_xref="InterPro:IPR008775"
                     /db_xref="UniProtKB/TrEMBL:Q6L732"
                     /gene="kanJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SkaJ19.27"
                     /product="putative kanamycin biosynthetic protein"
                     /protein_id="CAF31594.2"
                     /sec_met_domain="PhyH (E-value: 5e-20, bitscore: 63.9,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALAAPPGELTLALTPDDKTLDPASLDRALAILAEHGILVLTGML
                     RTRLTDQLRTAMLDDLPEVLRQQDVPTNFVPGHVQQDPPVRESLLFPDVLLNPVVYQIT
                     HAVLGADARNAVYSGNMNLPGSHEQPVHLDEPHLWPGISHPPYCLCVDVPLIDFTLENG
                     STEYWPGSHVLNPDECYDERGCVLPAELERRRAVAPPVRFPIPVGSVVIRDGRLWHRGV
                     PNLSAAPRPLLAMTHYTEWFDMPPIQLPDTVKSWVDGSDRHTHAHFVAGDVDHLTGDHP
                     FAVR"
     regulatory      31949..31953
                     /gene="kanK"
                     /note="ORF SkaJ19.28"
                     /regulatory_class="ribosome_binding_site"
     gene            31949..32920
                     /gene="kanK"
     CDS             31970..32920
                     /codon_start=1
                     /db_xref="GOA:Q2MFU6"
                     /db_xref="InterPro:IPR001509"
                     /db_xref="UniProtKB/TrEMBL:Q2MFU6"
                     /gene="kanK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 74.4;
                     E-value: 1.8e-22)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SkaJ19.28"
                     /product="putative (NDP-)sugar oxidoreductase"
                     /protein_id="CAF31595.1"
                     /transl_table=11
                     /translation="MGVVRALNAARHHVVVASRGYSPALLPEGVRAVRLERTEPDAYTR
                     LVAAEKPDAVIDLTCHDAADAAVTLRACAGVDRVVVVSSVTAAGPATTTPVTEATAAPP
                     LSEYGIDKLAVEETVRAAWADGTSQALLVRLGAVYRLGADLDGQLAEDGCWLAHAAAGA
                     PAVLADDGAARWNLLHADDAGAALAELLANDRARGVLVHLASRHPLPWRELYERVHHAL
                     GRPFNPVSVPAEWAAEQLEDAEFLAETSRWDQVFDLGLLDRLAPSYQERGGPSRVTEVA
                     LWLIRQGRVGDAELGAEIQELPARLAAVRTAPGLV"
     regulatory      33032..33039
                     /gene="kmr"
                     /note="ORF SkaJ19.29"
                     /regulatory_class="ribosome_binding_site"
     gene            33032..33879
                     /gene="kmr"
     CDS             33046..33879
                     /codon_start=1
                     /db_xref="GOA:Q75PS4"
                     /db_xref="InterPro:IPR010769"
                     /db_xref="UniProtKB/TrEMBL:Q75PS4"
                     /function="kanamycin resistance"
                     /gene="kmr"
                     /gene_functions="resistance (resist) ArmA_Rmt (Score: 157;
                     E-value: 3.5e-48)"
                     /gene_kind="resistance"
                     /note="ORF SkaJ19.29"
                     /product="16S rRNA methyltransferasease"
                     /protein_id="CAF31596.1"
                     /transl_table=11
                     /translation="MSQSASDEDPKLTRVVEAVRGGRRYRSVTDQAVRRLARAALAVEG
                     GDVTRATKRTKRGLHEVFGAFMPMTPKYEALLRDVREAVELDDPEAIRTALKPALGAHS
                     STRERLPILTEMYAEVFDRLDTAPATVRDLACGMNPLTVPWMPLPAGTTYLASDIDHRL
                     MDFAGTVLTALGVPNRVEVRDLLTDPDPEPADVTFLFKAVPCLEAQGKGLGWKLLDQIN
                     SPVLVVSFPTKTLGRRSRGMYQTHSAEFARRVAERPWKCDEIEFGDELVYVVTKG"
     misc_feature    33079..33081
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            33951..33955
                     /gene="kanM2"
     regulatory      33951..33955
                     /gene="kanM2"
                     /note="ORF SkaJ19.30"
                     /regulatory_class="ribosome_binding_site"
     gene            33962..35206
                     /gene="kanM1"
     CDS             33962..35206
                     /codon_start=1
                     /db_xref="GOA:Q6L729"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q6L729"
                     /gene="kanM1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 271.3;
                     E-value: 2.6e-82)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SkaJ19.30"
                     /product="putative 2-deoxystreptamine
                     4-(N-acetyl-)glucosaminyltransferase"
                     /protein_id="CAF31597.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 6.1e-34,
                     bitscore: 108.3, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLRLTPFYHHDCVDSWPAEFDAVGGMQVQILRMSRALAELGVR
                     QQVLTVGFPGLPRVRRDSENLVVRITRAPLPRLRSRITGLVGLNQAWLAAALTECVKLR
                     RRWPADLIQVHLDGQLWALLAGPVAARLVGVPYTVTVHCSRLAVYQPMSTVDRIQHPLV
                     TAVERWALRRAAGITTLTERTATVLAAELGAAQRVIDVVPDAVDPDRAEAAPAEVERLK
                     KRFGLPQEGGPVIGFVGRIAHEKGWRHAVQAVAELADAGRDFTFLVVGDGPQRADMEAA
                     VAEAGLTDRFVFTGFLPNDEIPAVMTALDVLLMPSVHEELGGSAVEAMLAGTPVAAYGV
                     GGLCDTVGKVTPSLLAAPGQVAELARTVKRVLDDPAPVLAELRAGREWLADEFGVHHAA
                     GLALAHYERVLGKER"
     regulatory      35256..35259
                     /gene="kanL"
                     /note="ORF SkaJ19.31"
                     /regulatory_class="ribosome_binding_site"
     gene            35256..36272
                     /gene="kanL"
     CDS             35265..36272
                     /codon_start=1
                     /db_xref="GOA:Q2MFU3"
                     /db_xref="InterPro:IPR004881"
                     /db_xref="InterPro:IPR010914"
                     /db_xref="UniProtKB/TrEMBL:Q2MFU3"
                     /gene="kanL"
                     /note="ORF SkaJ19.31"
                     /product="putative kanamycin biosynthetic protein"
                     /protein_id="CAF31598.1"
                     /transl_table=11
                     /translation="MRQDWQHLDESDVRVRPGRRSSRPRSKNRPEHADARSAMVVGVDR
                     GRWTCVLDSDPESRITAMRARELGRKSAVIGDRVDVIGDLSGKPGTLARMVRVARRDSV
                     LRRTADDTDPYERVVVANAEQLVIVCALAAPQPRAGFIDRALVAAYAGGLRPVLCLTKA
                     DLKGPEDVVSTYAHLDLPIVVTRSDRAPDALREQLAGRVSALVGHSGVGKSTLINILIP
                     QARRVTGEVSAIGKGRHTSTSAVALPLPDGGWAVDTPGIRSFGLAHVTSDDVLDAFPDL
                     SDGAEDCPSGCRHLGAPHDSGCGLERLSEADPARARRLESLRRLLRSHAGIEEE"
     gene            36307..36705
                     /gene="kanO"
     CDS             36307..36705
                     /codon_start=1
                     /db_xref="HSSP:P37552"
                     /db_xref="InterPro:IPR006175"
                     /db_xref="UniProtKB/TrEMBL:Q6L727"
                     /gene="kanO"
                     /note="ORF SkaJ19.32"
                     /product="putative kanamycin biosynthetic protein"
                     /protein_id="CAF31599.1"
                     /transl_table=11
                     /translation="MSRLTHISAPEGVAPATAYTHVVMGTGRFVAISGQLALDEDGKLV
                     GEGDAAAQAHQVFENLRRCLTAAGATFDDVVKLTYFVTDMAHMRAIRGARDAFLDPERL
                     PASSAVQVGALVAPEYLMEIEAFAVVAE"
     CDS             complement(36729..37400)
                     /codon_start=1
                     /db_xref="InterPro:IPR001395"
                     /db_xref="InterPro:IPR004155"
                     /db_xref="UniProtKB/TrEMBL:Q6L726"
                     /gene="kanP"
                     /note="ORF SkaJ19.33c"
                     /product="putative kanamycin biosynthetic protein"
                     /protein_id="CAF31600.1"
                     /transl_table=11
                     /translation="MPRSHEINRRVTSAPALSVCDLRRREGSAVRLAAMDEELRTVTER
                     LRAEAGGSKEYERLVATGDLEELAEVLVSPGQPLWTRELAAVLLGVAGDRRAFESLVLL
                     LNHRDAPRCAAAAYALARLGDPRTARAAAALATNELRVAYALHPVRLLTELRAPESAPA
                     LITTLRRRLAPHDPFGKIALACVEGLGALGDPRARPVLTAARAHPRLAAAASAALARLP
                     E"
     gene            complement(36729..37425)
                     /gene="kanP"
     misc_feature    complement(37263..37265)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     regulatory      complement(37414..37425)
                     /gene="kanP"
                     /note="ORF SkaJ19.33c"
                     /regulatory_class="ribosome_binding_site"
     regulatory      37642..37645
                     /gene="kanD3"
                     /note="ORF SkaJ15.16"
                     /regulatory_class="ribosome_binding_site"
     gene            37642..39434
                     /gene="kanD3"
     CDS             37653..39434
                     /codon_start=1
                     /db_xref="GOA:Q6L725"
                     /db_xref="HSSP:P00348"
                     /db_xref="InterPro:IPR006108"
                     /db_xref="InterPro:IPR006176"
                     /db_xref="InterPro:IPR008927"
                     /db_xref="UniProtKB/TrEMBL:Q6L725"
                     /gene="kanD3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095:3-hydroxybutyryl-CoA dehydrogenase (Score: 304.4;
                     E-value: 1.1e-92)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SkaJ15.16"
                     /product="putative dehydrogenase"
                     /protein_id="CAF31601.1"
                     /transl_table=11
                     /translation="MDAPLNTVAVIGLGTMGTGIAEVLARAGREVIGIDISQAAATRAV
                     TALETSTARAVRRERLTDEERRGILARFRTFTDLQAAADVDLVIEVVPESYEIKQRIVR
                     ELDAVVRPETIIATGTNALSVTRLAAESARPERVLGLHFFNPAPAMKLVEIVSSVLTAP
                     AAVAAVTELAYALGKEPVAVGDRPGFVADGLLFGYLNQAAAMYEAKYASREDIDAAMKL
                     GCGLPMGPLALLDLIGVDTARTVLDAMYAESHDRLHAPAPVLKQLSEAGLTGRKSGRGF
                     YTYAEPGSTEVVRDALTPPEGERSVPSRAVRAVGVAGSGTMASGIAEVFAKAGYDVVLA
                     ARSEEKAQLARARIGKSLARSVEKGRITAESAAETLERITPAGSYEAFADVDLALEAIA
                     EDLDVKQQLFATLDKVCKPGAILATTTSSLPVVACARATSRPRDVIGMHFFNPAPAMKL
                     VEVVRTVLTSDEVHATVREVCAAIRKHPVDCGDRAGFIVNALLFPYLNNAIKMVQEHYA
                     TLDDIDAAMKLGGGYPMGPFELLDVVGLDVSLAIEKVLHREFRDPGLAPAPLLEHLVAA
                     GCLGRKTGRGFREYARR"
     regulatory      39531..39534
                     /note="ORF SkaJ15.17"
                     /regulatory_class="ribosome_binding_site"
     gene            39547..40356
                     /gene="kanU"
     CDS             39547..40356
                     /codon_start=1
                     /db_xref="GOA:Q2MFT9"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR012287"
                     /db_xref="UniProtKB/TrEMBL:Q2MFT9"
                     /gene="kanU"
                     /gene_functions="regulatory (smcogs) SMCOG1215:TetR family
                     transcriptional regulator (Score: 199; E-value: 1.4e-60)"
                     /gene_kind="regulatory"
                     /note="ORF SkaJ15.17"
                     /product="putative regulatory protein"
                     /protein_id="CAF31602.1"
                     /transl_table=11
                     /translation="MSKAAKSSRNASPDAPESAAGSRAAAQRLKMRRELAAAAMELFAT
                     KGYEATTVDEIAAAAGVARRTFFRHFRSKEEAIFPDHDDTLVRAEEVLNAAPAHEHPLD
                     TVCRGIKEVMKMYAASPAVSVERYRLTREVPTLREREIASVARYERLFTRYLLGHFDEQ
                     AHHDGNDDPLLAEVAASAVVTAHNHVLRRWLRAGGQGDLEAHLNHAFGIVRLTFGTGIG
                     AGRSSAPATAPATVSAQGEVLVTVARTDAPLDEVMRTIEKALRERAS"
     regulatory      40746..40750
                     /note="ORF SkaJ15.18"
                     /regulatory_class="ribosome_binding_site"
     CDS             40758..>41573
                     /NRPS_PKS="Domain: PKS_ER (52-270). E-value: 1e-17. Score:
                     56.1. Matches aSDomain: nrpspksdomains_CAI96521.1_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MFX4"
                     /db_xref="InterPro:IPR002085"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="UniProtKB/TrEMBL:Q2MFX4"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028:crotonyl-CoA reductase / alcohol dehydrogenase
                     (Score: 214; E-value: 4.8e-65)"
                     /gene_kind="biosynthetic"
                     /note="ORF SkaJ15.18"
                     /product="putative crotony-CoA reductase"
                     /protein_id="CAI96521.1"
                     /sec_met_domain="ADH_N (E-value: 1.7e-09, bitscore: 28.8,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.8e-10, bitscore:
                     32.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEILDAIQSQDAQSADFAALPLPDSYRAITVHKDETEMFAGLDT
                     RDKDPRKSLHLDDVPVPELGPGEALVAVMASSVNYNSVWTSIFEPLSTFGFLERYGKVS
                     ELTKRHDLPYHVIGSDLAGVVLRTGPGVNSWKPGDEVVAHCLSVELESSDGHNDTMLDP
                     EQRIWGFETNFGGLAEIALVKSNQLMPKPGHLSWEEAAAPGLVNSTAYRQLVSRNGADM
                     KQGDNVLIWGASGGLGSYATQFALAGGANPICVVSSEQKADICRSMGAEA"
     aSDomain        40914..41567
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAI96521.1_PKS_ER.1"
                     /evalue="1.00E-17"
                     /label="CAI96521.1_PKS_ER.1"
                     /locus_tag="CAI96521.1"
                     /protein_end="270"
                     /protein_start="52"
                     /score="56.1"
                     /tool="antismash"
                     /translation="SLHLDDVPVPELGPGEALVAVMASSVNYNSVWTSIFEPLSTFGFL
                     ERYGKVSELTKRHDLPYHVIGSDLAGVVLRTGPGVNSWKPGDEVVAHCLSVELESSDGH
                     NDTMLDPEQRIWGFETNFGGLAEIALVKSNQLMPKPGHLSWEEAAAPGLVNSTAYRQLV
                     SRNGADMKQGDNVLIWGASGGLGSYATQFALAGGANPICVVSSEQKADICRSMGA"
     CDS_motif       41430..41492
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAI96521.1_0001"
                     /evalue="9.50E-04"
                     /label="PKSI-ER_m5"
                     /locus_tag="CAI96521.1"
                     /protein_end="245"
                     /protein_start="224"
                     /score="11.9"
                     /tool="antismash"
                     /translation="GDNVLIWGASGGLGSYATQFA"
ORIGIN
        1 gatcctggag atgcgcgcca tcaccaagac gttccccggc gtcacggcgc tctccgacgt
       61 gaacctgacg gtgcgccccg gggagatcca cgcgatctgc ggggagaacg gcgcgggcaa
      121 gtcgacgctg atgaaggtcc tcagcggcgt ccatccgcac gggagttacg acggggagat
      181 cctcttcgag ggcgagccga tggccttcaa ggacatccgg gccagcgagc gccggggcat
      241 cgtgatcatc catcaggagc tggcactcgt cccccacttg tcgatcgcgg agaacatctt
      301 cctcggcaac gagcaggcgc gcggcggctt cgtcgactgg aacggcaccc tgcgcagggc
      361 gggcgcactc ctgaagcggg tcggtctgcg cgagaagccg cagacgccgg tcgccgacat
      421 cggcgtgggc aaacagcagc tcgtggagat cgccaaggcc ctgtcgaagg aggtgcggct
      481 gctcatcctg gacgagccga cagccgcgct caacgacgac gacagcgcga agctgctcgg
      541 cctcatcggg gaactgcgcg agcagggcat cgcctgcatc atcatctcgc acaagctgaa
      601 cgagatccgg gccgtcaccg acgcggtgac catcctgcgc gacgggcgca ccgtcgaaac
      661 cctgacggtc cgtgagactc cggacgccga ggccgagttg tcggaggacc gcatcatccg
      721 cggcatggtc ggccgcgacc tcgaccaccg cttccccgac cgtacgccct atgcgggcga
      781 ggacgcgggc acgctcgcgc tgtccgtcgc gggatggacc gtgcggcacc cggtcgacca
      841 gcagcgcacg gtcgtcgacg acgtgtcgct gaccgtgcgg cgcggcgaga tcgtcggcat
      901 cgcgggcctg atgggcgcgg gccgcaccga actcgcgatg tccgtcttcg ggcgctcgta
      961 cggcgtctac gtcgccgggg acgtggcggt gaacggccgc ccggtggtga cgcggaccgt
     1021 ccccgccgcg gtcgacgcgg gcatcgcgta cgtcactgag gaccgcaagc ggtacggcct
     1081 caacctcatc gacgacatca accgcaacgt ctccctggcc tcgctgcccg gcatgcggcg
     1141 ccggggcgtc gtggacgagc accacgagcg ctcggtcgcc gagcgctacc gcaaggccat
     1201 gaacatcaag gcgcccaccg tcttcgagga ggtgggcagg ctctccggcg gcaatcagca
     1261 gaaagtcgtc ctgagcaagt ggatccacgc cgaccccgag gtgctgatcc tcgacgagcc
     1321 gacgcgcggc atcgacgtgg gcgccaagta cgagatctac acggtcatcg acgagctcgc
     1381 cgcgcagggc aaggccgtcc tgttcatctc ctccgaactc cccgagctgc tcgggatgtg
     1441 cgaccggatc tacacgatgg ccgagggccg cctgaccggt gaggtcacgc gcgcggaggc
     1501 cacccaggaa gtcctgatgc gccacatgac ccagaccaga agccccaaga gctgaggccc
     1561 gccatgacga ccacgaccac tcccccgggc tcctcccggg acgcgtccga cgccccgcca
     1621 cccgcgcggt ggccggcggg cgcgctgctg ctgcgaagcg tgcgctccaa cacgcgccag
     1681 tacggcatgc tcatcgccct ggcgttcctc gtcgtgctgt tccagatctg gaccgacggg
     1741 acgctgctgc tcccgaacaa cgtctccaac ctgatccagc agaacggcta catcctcatc
     1801 ctggccatcg gcatgatgat cgtcatcatc gcgggccaca tcgacctctc cgtgggctcg
     1861 ttggtcgcct tcgtcggcgc catgtcggcg gtcatgatgg tcaagcacga catgccctgg
     1921 gtgctcgccc tggtcctctc gctcctgatc ggcgcggtcg cgggggcctg gcagggcttc
     1981 ttcatcgcgt acgtcggcat cccctcgttc atcgtgacgc tggccgggat gctgctcttc
     2041 cgcggactca cccagatcgt ccttgagggc cagtcgctcg cgccgttccc cgacgggttc
     2101 cagaacatcg ccaagggctt catcccggag atgggcccct acacccagta ccacaacccg
     2161 acgctcgtcc tcggcctgct cgccgtcgcg ttgctgctcc tgcgtgaacg gcgcgctcgc
     2221 aagcgccagt tggcgtacga gctcgatgtc ctgccgaccg gtctgtgggc ggccaagtgc
     2281 gtggcgatga ccgcggccgt ggtggcgttc accctcaccc tcgccagctt ccacggcgtg
     2341 cccgtcgtca tgctcatcat gtgcggcctg ctcatcgcgc tgggctatgt catgcgcaac
     2401 gccgtcatcg gccgccatgt gtacgccctc ggcggcaaca aggccgcggc gaagctgtcg
     2461 ggcgtcaagg acaagcgggt caccctcctg gtcttcgtga acatgggcgt cctcgcggcg
     2521 ctcgcgggct gcgtgtacgc ggcgcgcctg aacgcgggca ccccgcaggc cgggctcaac
     2581 ttcgaactgg aggcgatcgc cgcctcgttc atcggcggcg cgtcgatgag cggcggcgtc
     2641 ggcacggtcc ttggcgcggt catcggcggc ctcgtcctcg gcgtcctgaa caacggcatg
     2701 tccctggtcg gcatcggcac ggactaccag caggtcatca aggggctcgt actgctcgcc
     2761 gcggtcggct tcgacgtctg gaacaagcgc aaggcgggcc gctagggccc ttctggcgga
     2821 tctccgtggg agaaggagcg gcgttcggtg cgtgccctcg gcgtgcggtg tgaagggtca
     2881 tgtggcggag ccacctgtcc cttcgcgccg tgcggcgagg gtgcgtgccg ggcgtcgcga
     2941 cgccgcggag atccgccaga agggccctag ggcccggcgc aggtggtggc ggcacgccgt
     3001 caccacctgc gccccgccct cccgtcaggc ggccgccacc tcgatcatcg agagcgggtt
     3061 cggcgccccc atcggcgtca cggacacgat ggagagcccg gccctgccgc agagctcgtc
     3121 gaaatcggcc cgggtgcgtt ccctgccgcc caggttcacg agcatgttca gatcgctcag
     3181 atacgcgaac cccggggccg ccgggtcgac ggcctcgggc aggacgtgct ccaggatcag
     3241 cacccggccc tcgggcggca gcaccgcgcg acagtggctc aggatggtca ccgcccgctc
     3301 gtccggccag tcgtgcagga tgctcttcag gaggtagagg tcggcgccct tgggggccga
     3361 ctggaagaag tcaccggcca ccgacgagca ccgctcggtg agcccgtgcc gctccagcgt
     3421 cgcgggtgcc tgggccaggc cctccgccgt gtcgtagatg atgcccgtga ggcccgtgtg
     3481 ctccttcagt acggcggaga gcagcgtgcc gtcgccgccg ccgacgtcgg cgacggtggc
     3541 gaacctggtg aagtcgaagg cgcggggcag cgtggcggcc gccgccccgg tgctctgact
     3601 catcgcctcg ttgaaccggg cggactcctc gggatgctcc ctgaggtggc cgaagaagtc
     3661 cgtgccgaac accgtgtcga aggcgggctc acccgtccgt acgacctcgt cgaggtgttc
     3721 ccagccgcgc agcatcgtcg ggtcggacat catgagcacc agggacgcga cgttgccggg
     3781 tcgtcgcgag tcgagcaggg cgcccgtggg cgtcaccgcg aagacgcccg gcgtccgctc
     3841 cgccaccacg ccgatgcccg cgagcgcgcg cagcagccgg atcatgccct cggggcgggc
     3901 cccggcctct gcggcgacct cggcggcggt ccgctccttg tcgccgatca gctcgaccac
     3961 ccgcatccgg gcggccgcgc gcagcgtctg cgccgccatg ctcccgaaga cgagctggac
     4021 cagttgcctg gggtccgccc cgtcccccgc ccccgttacg cccccggcat ccgccgctcc
     4081 ggttccaccg ttcgccacag tcgttcccct tccgctccgg acggtgcccg gcggccgaca
     4141 cggaccgccg tgcgaggtag ggaagcctag ctctccccgc ggtcctcgcg gggtcgcaat
     4201 cggccctgat ccgcccggcc ggggagccgc tcccgcgggc cgcatagagt cgtggtgcga
     4261 gacccgccgc cccttcaccg gcgggccccg cgttcaccac cacgaccgac cacgaggagc
     4321 agccgtgacc gacccggcgt ccaccgcact gcagcaggag atcgcccggg atctccaggt
     4381 gtccgcgagc ttcgacccgg cgcgcgagat cgagcgccgc gtcgccttcc tcaccgagcg
     4441 gctgacctcg acggggctgc gctcgctggt gctcggcatc agcggagggg tggactccac
     4501 gaccgcggga cggctgtgcc agctcgccgt cgagcgggcc cgcaccgccg ggcacgaggc
     4561 gaccttctac gccatgcgcc tgccctacgg cgtccaggcc gacgagaagg acgcgcagct
     4621 cgcactgggc ttcatcgccg ccgaccaggt cctgaccgtg gacgtgaagg ccgcgagcga
     4681 cgccgcgctg gaggccgcgc tcaccggcgg ggtcgtcttc agggacgagc gccaccagga
     4741 cttcgtgcag ggcaacatca aggcccggca gcggatgatc gcccagtacg cggtcgcggg
     4801 cgcgcgggac ggtctggtgg tcggcaccga ccacgcggcc gaggcggtct ccgggttctt
     4861 caccaagttc ggcgacggcg cggccgacgt cgtgccgctg accggtctga ccaagcgccg
     4921 ggtgcgggcg gtcgccgacg cgctcggcgc ccctgccgag ctggtgtgga aggtcccgac
     4981 ggcggacctg gagacgctcg accccggcaa gccggacgag gacgcgctcg gcgtgacgta
     5041 cgacgagatc gacgacttcc tggaggggaa gccggtgtcc gacgcgtcgt tccggtcgat
     5101 cgtcggccgc taccgcctca cggaccacaa gcgcaggctg ccgatcgcgc cgacggcctg
     5161 agcgtcggcc ctcgcgaggg cgggtgggcg gcgccacccc cgtgggggcc gcccccgccc
     5221 accgcctcac gcctggggcg gcatccaggc ctgcagcgtc gccgggtcga tcggcagcga
     5281 gatgtgctcg tgcgtgatca gccacgtgcc gctcacccgc cgacagcaca cggtcgaccg
     5341 caccagcatc gcgctctgca tcccgttcgt acgggttccg gaatccaggt gcagcatgtg
     5401 ggcgaacgcg acgtcgtccc cgaccgcgac ggtgagctcc cgcgtctcca gcgtgatggg
     5461 cccctcatag ccctcgaacc accgcacgaa gttcttgcgc acttcgccgt gccccgcgaa
     5521 ccgcatcggc ggcacgacgt cgaagtagac gacgtccggc gcgaaaagcg gcatgagccg
     5581 gtcgatgtcc ttcgcctgcg cggcgtcggc acggctctcc aacaacgccc tgacctcgat
     5641 ctcgtctctg gtcatagcgg cctccattcc tgagttccgg ccgccgcgac ctcatctggc
     5701 ggcagcccct gtggtgggtc ccagtgatcc gacgagacag gaggccggaa tgtcaggccc
     5761 gctcagtcca ggccgaggac ctgccaccac gacggcagtt cgatccgcgt gccatcgggc
     5821 ctgaactcgg tggtggtcag cgggagttcc ccctcggcaa ggaccgcgag gcccgcggcc
     5881 gcgacgtact cccgcaccgc ctcgtcgacg acctcggccg gtgcgaggcc gtgcgcgaag
     5941 accggcgcca gcttcggcgg cgggcccgtg gggctctgcg ccaggccgag caggacgggc
     6001 ttggcggcct cggacagttc gacgacgaag gctctgccgc gctcccccac caggcgcgcg
     6061 atgttgtcga gcagcggctg cctgtcgtcg ggatcgcact ggtggagcac gccgcgcatg
     6121 tagacgttca catcgccgag ttccgcgtgc agctgctcgg cgacgctcca ctcggcgatg
     6181 tcgagctgcc ggaagtcggc ctgtcccgcc gggtccgccc gccgggcgtg atcgagcgcg
     6241 gcggcggaga tgtcgacgcc gaggacgcgc ggatagcggt cggcgaggaa ccgcgtctgg
     6301 gtgccgttgc cacagcccag atcgatgatg ggcagccccg cggcggccag gtgcggctcg
     6361 aagagggcga ggtggagtcc cgcggtcaga gcgggttcgg cgtcccagaa cacggcgccc
     6421 tgttcgtcgg gcgcgtcgct ccagaacgac tcccaggcgg cccggtactt actcgtgacg
     6481 ctcatgacca gctccccagg gtgtgacaag ggccgccgaa cccgacggcg agatcggtgt
     6541 accgcgcccc ggggcgcgcg gacaagtcac ccgcgcgatc cttcacggct cgttcgacag
     6601 acgccgccgg acacgcgccg gtcgtgccgg gcgcacgccg ctcccggccg gggacgctcc
     6661 gcgcgcccgg ccccgcgcgc taccgccggg gcagcgccag ttcgaaccag acggtcttcc
     6721 ccgcgttcgt acggctcgtg ccccactcct tggcgagcgc gctcacgacc cgcaggccac
     6781 gcccgaactc gtcgtcgccg cccgcgctcc ggagcgtcgg cagcgtgtgg tcgtcgtcct
     6841 cgacctcgca catcagcacg gcggaacgga ccaggcgcag ttcgagccgc tcgctgcggg
     6901 agtggcgtac gacattggtg acgagctcgc tgacgagcag ctccgcggtg tcggcgagcg
     6961 cgccgaggga ccactcccgc agctgcgcgc ggaccagctc gcgggccctg ctcacctcgc
     7021 ctggcccggt ctcgaaccgc cagtgcgcga cgtcgtcggc ggcgatgccg ttgagcctgg
     7081 ccatcaggag cgccacgtcg tccttgcggc cgccgcgggt gttgagcgcc cggatgatcg
     7141 tgtcgcaggc gtcgtccatg gaggcggcgg ggtgcgcggc ggactcggtg agcgtggcga
     7201 ggccgacgcc gatgtcctcg ccacggacct cgacgagacc gtcggtgcac atcagcagcc
     7261 ggtcgccggg cgcgaccctg atgcgtacgg attcgaaggg cacgccgccg acaccgatgg
     7321 gcgcacccgt cggcaggtcg aggagttcgc tgcggccgtc cgccgcgcgc accaggacgg
     7381 gcgggatgtg cccggcgttg gcgaggctca gctcgctcgc gatggggtcg tagaccgcgt
     7441 agagacacgt cgccagatag tgctcgccga ggcgctgtgc gaggtcgtcg aggttgcgca
     7501 ggagctgctc gggcggcagg tcgagggcgg ccatcgtctg caccgcggtg cgcaactggc
     7561 ccatcatcgc cgccgagttc aggccgtggc ccatcacgtc gccgacgacg agcgcggtcc
     7621 gcgaccccgg gagcttcacg gagtcgaacc agtcgccgcc gacccggccg agcagtgtgc
     7681 ccggcagata gcgggtggcg atgtcgccgc cgggcatgcg ggggtcgatg tgcggcagca
     7741 tgctgtcctg gagggtgtcg gcgacgctct cctggtaggt gtacatgcgg gcgttgtcga
     7801 gcacgaggcc cgcgcgggcg gccagttcgg agccggtgac gcggtccatg tcgttgaaga
     7861 cggggcgctc gcggtggcgg agcaggatca tgaagccgag caccacattg cgcgccttga
     7921 gcggtacgac gagcatcgag cggtggttga tcagcgggcg gatgtcgcgc ttctcgaact
     7981 gggaggcgat ggcgttgccc atctcctcgg tgatgcgcgg cacgagcacc gggtctccgg
     8041 aggtcatgca ctggaagaac ggggtgtgca ccgggaacgg catggactcg ccgaccggca
     8101 ccacgtcgtc ccagcggccc ggttcgtccg tgtgttcaag ggcgacccgg tgccacatcg
     8161 tggtctcgtc cggcaccccc tcggggaacc cctcgcccgc gacgacctgt tcccgcaggt
     8221 aggtgcccgc gacgtccgtg aagcgcggca cgaccgcctt gctgacctcc acgatcgtct
     8281 gcgccagatc gagcgaggaa ccgatgcgcc cgctgacctc gttcaggaat tcgaggtgct
     8341 cgcgcacggc tgcgtactcg aggtcgtcgc cctcgtcgtc ggccgtgacc gcggcgggca
     8401 ggccgtgcgc ggcggcccgc gcggcgcgct gcctgcgttc cttgcgctcg gcgcgccggg
     8461 ccacgcccca gtcgggggtg acgggcaccc ggtcgtgctg gctgaactcg agtaccggat
     8521 agcccagttc gagcacctgc gcgacgatgc gggagctctc gccgacgctc atgctgggca
     8581 ggatctcggg cagtccgtcc gcgagccggt ccgcaccggg gaagtccgtg tgcagggcga
     8641 acccgggggc gatgctgccc cagtgcctga acgacgtggc cccctgagcc cggtcgtccc
     8701 gctctcccag ctccgcttgc tcaccctgct cgtcccggtc ctccgcgcgg ccggcgtcgg
     8761 tcagcgcggc ggcgtcggcg gcgagcacga gcagccgctc gggtcctggg ccgaccagcg
     8821 gatacgccca ccacagcacg tcgagacggc gggcggggtc gctgcccggc tcgtcgaggc
     8881 gggcgcgccc tgccgccggg taggagatgc ggccgtcgag ggaggtctcc aggtcggggc
     8941 cgagtccgtc gtactccccg tagggcccgg cggcgtcggg tatcgcgccg tgcaccggga
     9001 gcaggtcgcc cacggggcgc cccacggcgt cctccttggc gtacccgaag aggcgtcgcg
     9061 cgccggtgct ccagtgggag acgagaccgc tgccgtcgac gacgaccacg gccaacggga
     9121 tgcgtccggc catggcacgc tgcgccacag gcccgctgcc cggagtgcct tgttccatgg
     9181 cccttgcccc ttcccgcggc agcgcaagat ctgagccgcc accaaccacc gtacgaccgg
     9241 ggcaggttgc cgtgcggcgc aatacgggaa ttggccgcgg gccggacctc cggcgcacgc
     9301 ccgcgcgtcc tgtccgctct cagtcctcgt gccccagctg gaggtcacgc tcggtgcggc
     9361 cgccgcccgc gacctgcaac accgtggcga ccggcgggta gcccgccgcg atgacggtgt
     9421 actcgccgga cgacaggtcg atgaagcgga acgtgccgtc cgctcccgtg gtcagggtgt
     9481 cgacgacgtt gcccgcggcg tcgagcagcg tcacgcgcgc gtcctccacg ggccgcccgc
     9541 cgctggcccg cacggtaccc cgcagcacgg cgccgcccgc gagttccacg tcctgccggg
     9601 tctccctgga ggcctgcacg gagacgggca gcgcggcggg ccggaaggcg ggggcgctgg
     9661 ccgcgagcgt gtactcgccc gccaccaact ccgtgatcac gtagctgccc tcgcggccgc
     9721 tgcgggtggt ggcgacgacc tcgccgcgga cgtcggtgag ggtgaccgcg gcgtccctga
     9781 cgggcgtccc gtcggcggtg acgacggtcc ccgcgaggcg gcccgcgccg cccaggacca
     9841 cgtcgaggtc gacggggcgc tcgccgacgg tgacggtgac ggcctgcggc tggtgaccgc
     9901 ccgcggccgc gatgagcacg aacgagcccg atcccggcgt ggacagggcg taccggccgt
     9961 cctcgccgct ggcgccgcgg ccgatctgct gcccggcgac gtcgatgagg gtcagggccg
    10021 cgcggggcac cacggtgccg tcggggtgct gcacggtgcc gcacaccggg acccccgcgg
    10081 tgtacgtcga cgtacgggcc tgggggacgg gcgcgggctc ggcggcgggt gcgttctggg
    10141 aagctgcgct ggacaacagg ggggtctcct tgaggaagaa ggcgatcagc atgccgagga
    10201 cgagcaccgg caccaggtag aggaagatcc gcggcatcgc gtcggcgtag gcctcgatgt
    10261 agccgtcgcg cagcgccggg ggcagcgcgt ggacgagctg cggggtgatg gactcggcgt
    10321 cgggcagggc cgcccccgcg tccgccggga tgcggtcggc cagcgcgtcg gcgagccggt
    10381 tggcgaagag cgtgccgaag atggcggccc cgacgctgcc gccgatctgc cggaagtagt
    10441 tgttggcgct ggtggcggtg ccgaggtccg cgggccgcac cgcgttctgc acggcgagga
    10501 ccaggaccgg catgaccatg ccgataccgg cgccgagcac ggccatccag atgctgtact
    10561 gcagccgggg cgtgtcgact tcgaggcgcg agagcagcca catgcccact acggagaggg
    10621 cgccgccgag caccggatag atcttgtagc ggccggtgtg gctgatcagt tggccggaga
    10681 tgaccgaggc gccgacgatg ccgcccatca tcggcagcat caggaggccg gactcggtgg
    10741 cgctggcgcc gtcgaccatc tgcaggaagg tcggcagata actggccgct ccgaagaggg
    10801 cgattccgac gaccatgccc acaagaccgg tgatgttgaa gaccggatca cggaacaggc
    10861 gcagcgggat gatcggttct gccgcgaagt gctcggcgac gaggaagagc agcgccgatg
    10921 cgacggctcc cgcgccgagc cccaggatga cgcggtcgcc ccaggcgtac tcggtcccgc
    10981 cccagctggt gagcagcacc aggcaggtgg aggcggcggc gagcagcagc gcgccgagga
    11041 cgtcgagtct gccccgcgac gcgggcttgg gcagcttcag gaccaggctg acgacgagga
    11101 gcgtgaccag gccgaagggc acgttgaagt agaagcacca gcgccaggag gcgtggtcgg
    11161 tgaagaagcc gccgagcagc ggtcccgcca ccgaggcgag gccgaaggag gcgccgatca
    11221 ggcccatgta gcggccgcgc tgccggggcg gcacgatgtc ggcgatgatc gcctgtacgc
    11281 cgatcatgag accgcccgca ccgacgccct ggatggcgcg gaacgcgatg agctcgtcca
    11341 tggtccgcga ccagccggcc agggccgagc cgatgacgaa gatgacgatc gcgaactgga
    11401 agacgccctt gcggccgaag aggtcgccga gcttgccgta gatgggcagt ccgaccgtcg
    11461 aggtcagcag ataggccgtg atcgcccagg acatcttgtc caggccgtgc agctcaccga
    11521 cgatcttcgg gagcgcggtg gcgacgatca tctgctccag ggcggcgagc agcagggcga
    11581 gcatcagccc gacgaagacc atccggaccc ggcgggggct gagcccgtgc gccgtggccc
    11641 ccggagcggg gggcggcggg gcctgtgccg cgccccgctc ggggggtgcg tcggccgcct
    11701 cgacggcctc cgtgccgtcc cgctcgacgg ccttcaccag cgtcgtcccg cccacgtact
    11761 gctcccctcg tcgcgcctgc gccgcccatt tctcgcatta cgcgacaact gtgagcaagc
    11821 gcgacgagtc gccctctaac cgggccgcac gggcgttagt gccggtcgga gccctacggc
    11881 gtacaacgga gccgggacga aaaccactcg aaacggtgag cgtgagaaca accctgatgg
    11941 gttacgcggg agttggggct acttctcgac ctcggcggcg agcttgccga gcacggcgtc
    12001 gtagatccgc ccgaggccct tcggcgcgaa cgtcttctcg aagaagccgc cgatgccgcc
    12061 cgcgccgttc cacacggtgg agacgactac gcgggacttg ccctcgcccg ccggggtcac
    12121 ggtccaggtg gtgaccatcg aggagttgcg gtccttctcg accagttcgc cgtcgttcgg
    12181 ctcgccgacc tcgagcaggc agtccctgat gcgcttgctg gtggcctgca gcttccagtg
    12241 gacgagggtg ccctcgccgt cgccgccctc gcgcacctcg tactcgctga agtggtcgga
    12301 aaggatcttc tcgcgcgtgc cgttgtagtc ggccagtgcg tcgaagacat cgtcaggctg
    12361 tgccgcgatg atccgctccg tggtcgcctc gacctgcgcc attgcacttc ctccagcact
    12421 tggtttttcg gggagttcac ggagagccaa ccaccctgcg taccggcctc ccaaatcggg
    12481 tccgtgatca ggtgcgtgat caggcccgtg agccaagccg tgctcacacc ggcagcagcc
    12541 gcagggacac ccagagcgcg agggtcgaca ggacgagggc cgcgggcgtg gtgaggagac
    12601 cgaggcgggt gaactccctg aggtcgacgt cgtgttcgtg ctgatgtgcg atgcgccgcc
    12661 acaggagcgt ggcgagggag cccgcgtagg tgaggttggg tccgatgttc acgccgatca
    12721 gcacggcgag gacggcgcct ggcccggacg gcgcggccag cgggaccagg gcgaggaccg
    12781 cgggcaggtt gttgatcagg ttggcgagca gcccggcgac ggccgcggtg ccgagcagcg
    12841 cgggcagcga ggcgccgtcc ggcaggacgt ggccgagcgc gtcgccgagt ccgttgtcga
    12901 cgacggccct gacgacgacg ccgagcgcca ggacgaaggc caggaacggc agggaggccg
    12961 agcgcaggat cgccaccggg gtcgtacgac cgcgcagcag ggcccgtacg ccgaggacga
    13021 gcgccccggc cgccgcggcc caggccggat cgatgccgac ggccgaggcg acggcgaacc
    13081 cggcgagcgt ggcgacgacg gtcaccaggg cgaacagcgg catctcgggc ggctccgccg
    13141 tatcgccgcc gtcgacgggt gcgtcgagtt cggcggcgaa gaaccgctgg aacacggcgt
    13201 attcgacggc gatggcgacc agccagggga gcgtcatgag cagcgcgaag cgcgtgaagc
    13261 tcagccccgt cgcggtgaac gcgagcaggt tcgtcaggtt cgacacgggc agcaggagcg
    13321 aggcggtgtt ggacagatgg gcactcgcat agacgtgtgg tttgggcggg gcgcccatgc
    13381 gcgccgccgt ggcgaagacc accggggtca gcaggaccac ggtggcgtcc aggctcagcg
    13441 ccgcggtgat cacggaggcg agcccgaaga cggcggtcag gagccgtcgc gggcgtcgcg
    13501 cggcccagcg tgccatccag gtcccgcagg cgtggaagag cccctcgtcg gcgcagagtt
    13561 tcgccagtac gaggacgccc gcgaggaagc cgatcaccgg gccgagccgc gcggcctcct
    13621 cgcgcacgtc gtcgagcggg atcgcgccgc tcaggaccac gaccccggcg gccggtacgg
    13681 cgaaggccgc ctccggccag cggaacggcc ggacgacggc gcagaccagg accacgacaa
    13741 gggcggcgac ggacaggaac tctacgagca tgatccgatc atgcatcgcg tggtgtcttc
    13801 gccgccgccc ccggtggccg tactagaggc cgcgcgtcac gactggggcg gctggtcctg
    13861 gccctggtct ccgcccagtt gttccttgag cttgtcctgg gccgtgtcga cctgagagct
    13921 gtatttgccc tgggtcttgt cgtcgacgaa gtcgcctgcc ttgtcgatac ccttccccgc
    13981 ctggtcctca tgccccttga gcatctgctt gagcttgtcc atcacggaca tcgtcggcct
    14041 ccttggttcg agccgtcacc ttcagcatgc gggcacatcg gagctgctgc atccgcaggc
    14101 gcgggctcgg gcacaatgca ggagtggaac tgaacggtga gaaagtgctg ctgcggcccg
    14161 tgctcgacag cgatgtgaag aagctcgaca agatcgtcag agaacccgag gtggccgctt
    14221 ggtggtcgac ccccgatgac tacgaggaga tgctcgccat caccctcgac ggcgaggtca
    14281 tcggggcagt gcagtacgag gaggaggaag accccgagtt ccgccacgcg ggcatcgaca
    14341 tcttcctcac ggcgagtcgg cacggcctcg gcctcggcac ggacaccgtc cgcaccgtgg
    14401 cacgttggct gatcgacgag cggggacacc accggatcac catcgacccg gcggtggcga
    14461 acgcgggcgc gatccgcagc tacagcaagg tgggcttcaa gccggtcggc gtcatgcggt
    14521 catacgcccg tgaccacacg agcggcgtgt ggcaggacgc cctgctgatg gacctgctgg
    14581 ccgaagagct ggtctgacgg gtcggcccgt ccgaccccgg ccgcctgtgc gcccctgccg
    14641 cccgccgggc gcgcaggggc cctcacccgt cgccgacctc ggtgaggccg cccgtccggc
    14701 cgccgagctg accggcgagc gagcgggcga ccggcgtgcg gaaggcgcgt gcgagttcca
    14761 gaagaaacga ttcttcacca gagatgttca cgctgtccca gccgtgggag agggaggcgt
    14821 cgaagtcctt ggccgccccc gtccgcctgg cccgcagggc cacgtgcagg agacaggcca
    14881 gcgtcatcgc gtcggcggag cgcccgtgca gacccagctg ttccacccgg ctcttcacgg
    14941 ctcccggcag cgcgggatgg acgtagccgt gcagggagag gatcgcgtcc cgtatctcga
    15001 tcatcctgcg gtagacggcc agtcggcgcg gcgcgcgcgg ccacaccacc tcgacgatcc
    15061 gggagcgccg ccggtggagc gccacgtgcg gcaccgcctg caccagggtt cgccacaggg
    15121 gccacagcac ccacagggtc ctgatctgtg acggctggga gcgcatcgag ccccacaggg
    15181 gcaccagcag ggcggccgcc cgcaggaagc cgtgcaggct catcagcagg gacaggttcc
    15241 gcaggggcgg ctcaccgatg atcagccgtc caagggccac gcaccaatag atcccgacca
    15301 gagccgtgcc cgccccgaag atccacaggc tgaggcggag agaaggggcc gaggcccggc
    15361 agccctgcca cagacacacg tggacgcaga ccgtgttggc cacgatgtga ctgcccatca
    15421 ggatggccca gtacgcgctg agcgacgaag gaccgcccgg gttgtcgtgc tgttcccgca
    15481 cctggtcgag caggaccagg gcgaggacga ccagcgccac cgacgtgacg agtccccagc
    15541 gccaccagcg gtgctgggcc gccgccgtga cgaagtacag cacgcacccc gccgacaaca
    15601 ccccgaagag gttcctggcc agacccacct cgtgcacgct gcccgtgagg tcgagggcgg
    15661 ccctgatgac gaccggcagt tgcagcgcca tggcgaccgc ggccgtcgcg acggccagcc
    15721 acaggccgcg ctgggccgga ctccgggcgg cggcgggggc gcgcaacagg accaccgccc
    15781 ccatggcggc ggcactgacg tactgggcca cggtcgccgt atgggccaag tcagccccca
    15841 cgggtcgctc ccacgccgag tgcctcgccg aggtagtgaa gcacgtcgtc cgcgtgccgt
    15901 tcaccggcgg gctgttcgcc cctggtgcgg atcaggctgg ccagcatctc ggcctcctgc
    15961 tcccgccggg tggtgtagtc ggtgcgggcg agcagccgtt ggatcagctg cgggctgagg
    16021 tccccgaaga gctggggcgc atcgccccag ccctcgccca gttcgagcga ttgatgaccg
    16081 aagagcatgt ggccgatctc gtgcaggatg atgtggtcct gatgcacgcg ggccgtgcgc
    16141 tgctcgaaga agatgtggtc gtcgatgtcc gtggccagcc acaatccgca cgcgcccgcc
    16201 tgggccgcct gccgcggcaa ggcgtgcaga tgaaggggcc gctgacgctg ggccgcgagg
    16261 cgcgtacaga aggattcgac ggtgaagggg tgcggcaggc tgagtccgtc cacgatcgcc
    16321 tggcaacgct gtcggagttt cacatatata taagacatat gctctttccg taggccttga
    16381 gcggggcatc ggtagtaggc ggtcctgcgg acatgcattg accctcccga tcgcgaggac
    16441 agggtgctgc ggggtgcccg tgggatgcgc tcgattcact ccgtgtgctg gggaccgcgc
    16501 ccgtcttcgt cagccggtgg ggacaggttc tggatcttcc gggcctcgtt caccatgacc
    16561 agcaacgcgt ccaaggtgga gggcgaaagg ccttccgccc gaagcgcgag attgcgaatc
    16621 cggttgtccc tgagggccgt tgccagtgcg agttgagcgt ttacccgttc ggacacctcg
    16681 tcattgagga agtactcagg cggtaccccg aaatagtctg ccaggacacc gagttgttcc
    16741 agcgtgacgt ttcgtttctt gccggtggcc aattcccata ggtacgttcc cgagatggtc
    16801 ccgccggtgg tttctcttat gtcctgcgcg agccgcgcat aaccgggccg ggtgcccttg
    16861 tccggataga tggcgcaaat gagatctttg atgcgctggt cgagtttatc cagcagcagc
    16921 ctgccgcttt cggaacgctc cgccgcgccg tccctcatgc gccaccctct ccctgcccgg
    16981 aacgaaggat gagaccctcg ccgtagtgga cggctgtcac cgtacgccgt cgcccagcac
    17041 gtgaccatgg cgcccgtgat attccggcca cgctgtgacc agcactgtcc aactgttcgc
    17101 tatagcggac acgttgacgg tctttcatca gctggctact gtcgtcaccg gttgaacgcc
    17161 cgggtccgcc cggcgcggcg cacggcgggt accgccgtga tggcccgcgt gacgcgttcg
    17221 gccgttagca gcgcgccaga cgagaacctg atcccccgcc gtgccgaccg gcccggacca
    17281 gcaggctccg tcctcccccg ctccctatcg cttcggcgtc acttcaccgt ccattcgtgc
    17341 cgccttcggc tgcgccgata aggccgcccg cagcgcaccg ccacaatgga ttttcggctc
    17401 ctcacagaga agggcccagc cttggcacag caggttcacg gtagcgcgcc cgccacggtg
    17461 cgcgagagtg atatccaggc cgcctcgctt cccccggaaa gcaagtccga gctattccag
    17521 cggagttcgg tgcgcgttcc gctcgacctg ctcctgcccg cggtgtcccc ccgcatcgca
    17581 ggcgtggacg aacggcacgt ccggtcgctc gccgggatcg aggccccgct gccgcccatc
    17641 gtggtgcacc gcgccacgct gcgggtgatc gacgggacgc accggctgct cgccgcccgc
    17701 gcccgggggg agacggacgt ggaggtgcag ttcttcgacg gcggtgaggc cgatgccttc
    17761 gtcctcgccg tcgccctcaa caacgcccag gggctggcgc tctccccggc cgatcgcagt
    17821 acggcggcgg cgcgcatcat cgcctcccat ccgcactggt cggaccgccg catcgcccgc
    17881 gtcaccggcc tggccgccag cacagtgggc ggtgtccgca ggcgttcgac cgctcgaacc
    17941 gcacagccga acgcgcgcct cggcatggac ggccgcatcc gcccgcagga catcgcccaa
    18001 cggcgcaggc tggccgggca gttcctcgcc gagcagccgg gggcctccct gcggaccgtg
    18061 gcgaaggccg ccgggatctc cttgagcacg gcccacgacg tacggacgcg actgcgggcg
    18121 ggcgacgatc cgctgccccc cgcgctgtcc aggccgacgc ggccgcccgc cgcgccggac
    18181 agcgcggccg acgccgcgga ccggcccgcc aagccgtcct ccgcacgctc cccgcgaagc
    18241 cccgggcgcg cccccgtcgc cgccgatctc ctggaccggc tgcgcaagga cccctcgctg
    18301 aggttcacgg aggacggccg gatccttctt cactggctcg gcgccgccgt gctccgcgaa
    18361 cacggcgccg cacggttcgc ccgctgcgta ccgccgcaca ggaccgccgc catggcggcc
    18421 ctcgcccgca gctgtgcgga gggctggctc cgtctcgccg aatccctcga ccagcgcggc
    18481 aggtccgacg cgtgacccgg cgggagcagg ccgggtcctt cccccgatca cccctcgtgc
    18541 tccgcccact ccggagcacc cgtgcacagc gttcaaagga gcagacaccg tgaaggcact
    18601 cgtgttccac agccccgaga aggcgacctt cgaacagcgc gacgtcccca ctccccggcc
    18661 gggcgaagcc ctcgtccaca tcgcgtacaa ctccatctgc ggcagcgacc tctcgctcta
    18721 ccgcggtgtc tggcacggct tcggctaccc cgtcgtgccc ggacacgagt ggagcggcac
    18781 cgtggtcgag atcaacggcg ccaacggaca cgaccagtcg ctggtcggca agaacgtggt
    18841 gggcgatctg acctgcgcgt gcgggaactg cgcggcctgc gggcgcggga ccccggtgct
    18901 ctgcgagaac ctccaggaac tcggcttcac caaggacggc gcctgcgccg agtacatgac
    18961 catcccggtc gacaacctcc gcccgctgcc ggacgcgctg tcgctgcgta gcgcctgcca
    19021 ggtcgaaccg ctcgcggtgg cgctcaacgc ggtcagcatc gcgggcgtcg ctcccggtga
    19081 ccgggtcgcc gtcatggggg ccgggggcat cggcctcatg ctgatgcagg tcgcgaggca
    19141 tctcggcggt gaggtgacgg tcgtgtccga accggtcgcc gaacggcgcg cggtcgccgg
    19201 gcagttgggc gccaccgagc tgtgctccgc cgagccgggg cagctggccg aactcgtcgc
    19261 ccggcgcccc gagctcacgc ccgacgtggt cctggaggca tccggctatc cggctgcgct
    19321 ccaggaggcc atcgaggtgg tcaggccggg cggccgcatc ggcctgatcg gctaccgggt
    19381 ggaggagacg ggaccgatgt ccccgcagca catcgcggtc aaggcgctga ccctgcgcgg
    19441 ctcgctgggc cccggcggcc gcttcgacga cgccgtcgaa ctgctcgcga agggcgacga
    19501 catcgcggtc gagccgctgc tcagccacga gttcggcctc gccgactacg ccaccgcgct
    19561 cgacctggcg ctgtcccgca cgaacggcaa cgtgcgctcc ttcttcaacc tgcgcgacta
    19621 gggcctgtcc ggcaccacga cgcaccacaa cgcaccgcgc cacaccgcac gcaccgctcc
    19681 gccttcaccg tcgtcgcacc gttcgtgagg agaccaggga tgagcgtgtc acggggccaa
    19741 cgtgccaacg cgacggccat acgtctgtgg acgttcatgg ggttgatgga gctcgttccg
    19801 ctcttcccgc tctatcccct gctcttctcc gaccacggat tgtcgggatc ggcgatctcc
    19861 tcgctgctcg tcctgtggtc gatgaccacg ttcgtcctgg agatcccctc gggcgcgctc
    19921 ggcgacctgc tgtcccgcag gctgctgctc gcgttcagcg tgctgctgcg ggcgggcggg
    19981 ttcagcctct ggttcatcgc acccggctac tggtccttcg ccgtcggatt cctgtgctgg
    20041 ggagtctgtg acgccctgac ctccggcacc ctggagtccc tcgtctacga cgaactccag
    20101 gaccgcggcg aaggacatgc ctacggcccc gtcatgggca ccgggcgggc catctcgctg
    20161 ctcgccacgc tcaccgcact gctcctggcc gggccgctct tcgtcctcgg cgggtacggt
    20221 ctggtcggcg cggtcagcgt cggtgcgggc gtggcggcca ccatcaccgc actgaccttc
    20281 cccaatccac cgcgccacga gatcgaatcc gaacgcggcg gcttccaccg ctatctcgcc
    20341 accttcaaag ccgggttcgg ggaggtccgc agggaacggg ccgtcatgcg gctggtgttg
    20401 atcgccgcga tcctgcagag catgacggcc atcgacgagt actttccgct gctcgcccac
    20461 gagaacggcg cggccaagag cctcatcccg gtcctggtgg cgatccccgt gctgtgcgcc
    20521 tcggtgggca gctggatcgc gggccgctcc accggcgtct cgcgcaggac cgcgttcctc
    20581 accgtggcgg cgaccgggcc gctgctgctc ctcggcgccc agagccacca ccagtggggg
    20641 atgctctcga tcgccgtggc cttcggcatc atccagtggg gcatcgtggt gtccgggctc
    20701 tggctccagg acgccatcgt cggatcggcc cgcgcgacca tcacctccgt cgcgggattc
    20761 ggcgccgagg tctcctcggt cggctggtac ctggccgcgg ccaccgccct cacggtcacc
    20821 gacgtctccg gcctcacgtc gtggttcagc ctcccctgcc tcctgatcgc gggcctcacc
    20881 tggttctggt tcccggagcg accggcatcc gagccgaccg aaccgaccga accgcagccc
    20941 accacctact cgaagaggta atcactgtgt ccacgcaccc cgtcctggac tggagccgat
    21001 ccgccgaaca cctgcgccgc tcccacggcg tcaccaccga cccccgcccc gacgaggacg
    21061 gccactaccc ctgcgtactg acccggggca gcggcactcg cgtgtacgac ctggacggca
    21121 acgcctacct cgatctcacc ggatccttcg gctcggtgct catcgggcac gcggaaccgg
    21181 ccgtcgtacg ggcggtgacc gacgtcctga gcgaaggcaa tctcttctac accggcgcga
    21241 gcccgcgccg actggccctc gcggagcggc tccttgactg gttcccctgg tccgagcagg
    21301 ccatcttcta ccgcacgggg tcctgcgcgg tgtccgcggc ggcccggctc gcccagcacg
    21361 cgaccggccg caaccgggtg ctgagttccg gctaccacgg ctggcacgac tggcacctgg
    21421 aggcggtgcc cgaggccaag cccaagacct tcgagtcgta cgccaccgag ttccacaacg
    21481 acctggcgct ctaccgctcc tggctcgacc ggcacggcga ggagatcgcg gcggtcgtgg
    21541 tgacgcccga gccgcaccgc ttcgaccacg cctactacca ggagctgcgc gaggtggcca
    21601 aggagcacgg ctgcctgttc gtcgtggacg aggtcaagac cggcttccgg gccggggcgg
    21661 gcgggttcag cgccctggcc gggatcgagc cggacgccgt gaccgtctcc aagggcatgg
    21721 ccaacggaca cagcatctcc gccgtggtgg gccagcgaca gctcacccag gagctgagcg
    21781 aggcgcacgt ctggtccacc taccagaacg aacaggtggg gttcgccgcc gcgttggcgt
    21841 ccctggactt cctggagcgg cacgacgtgg cggccgtgac gcgccgcacg ggtgaggcgg
    21901 tccggcaggg cgtgctccag ctcttcgccg aacacggcct gcccgtcggg gcgccgggct
    21961 ggggaccgat gttcgagctg gacttcgacg ccgccgacga gggtctcgcc gagcggctcg
    22021 aagcggcgct gctgcgccac gggatcttct gcgacacggg cgacgacttc aacatgatgt
    22081 tccataccgc ggagcacacc gacgagctcc tcgagcggtt cgccgccgcg ctcggcgacc
    22141 tctgaggccg cggtgcgcat catctccgta caggaggcgg ccacccgcac cttcgacgtc
    22201 tgcgtggtgg gcagcggcgc ctccggtgcc atcaccgccg cggtgctcgc cgaacggggc
    22261 ctgtccgtgc tcatcctcga acagggcacc gcgatcccgc cgggcaccga ccacgacgac
    22321 gtcgaggacc ccgacacctg ggcgtacgca cgcgacgggg aaggctggag caaggagggc
    22381 tatccctgga gcgccatggc gttcggcggc ggcacggtgt tctacggcgg catctccttc
    22441 cgctacgaac agcgcgacct cgacccgccg cccgcgctcc tcggcgacgc cgactacgcg
    22501 cactggcggc tgcggctcga cgaactggag ccgcactacg actgggtgga ggaccggctc
    22561 ggcgtgagcg gcccgtccca cggccgggtg ggcgactacg ccttccccca ctacgcgcgg
    22621 ggctcgctgc cgcacacccc gatgggcggc gcgctggccc ggggcgccga cgccctgggg
    22681 ctgaccccgc tgtccacccc gatggcgatc agcggggcca gggaccggca cggccccggc
    22741 tgcgccgagc tgacgccgtg caccggcttc acctgcccgg tcaacgccaa ggccgatgtg
    22801 atcagccgca tcctggcgcg cgccgagggg gacgtgtccg tcgccctgga caccagagcg
    22861 gtgcggttcg tggcctcggc accggggcgg gcgaaacgtc tcgaagtgct cggcggcagt
    22921 ccccgcagcc gccgctcggt ccatgccgac cgcttcgtcc tcgcggccaa cgccatccag
    22981 tccgccgcgc tcctgctgcg ttcggcggac cggcgcgagc cggacggcat ggggaactcc
    23041 agcggtcagg tgggccgcca cctggccatg aagaacagcg tctacgtccg cggcaggacc
    23101 caggagcgga tcgtcgccca ccagccgctg cgccatcgct actccagcgt ctgcgtcctg
    23161 gaccacctgc gcggtgcgga gttccccggg cagctgggcg ggatcatcta cgaggccaac
    23221 ccgtgggagg accccgaggc cgaccgtcct ggcgccggtt cgctgctcca gctggagtgc
    23281 ctcctcggcg accgcccgca ggcccgcaac atggtgcggc tcgccaggag ccgggaccgg
    23341 gacgggctcc agcgcatcgt catggactac cgccagcacc ccttggacgg cgaacgcctg
    23401 gacgtgctcc aggggaaggc gaaggatgta ctgcacgcgg ccggggccga gcgcaccgag
    23461 tccgtcgaca gcgatttcgc gaccggcagc acgcatctgc acggcacgct gcgcgccggt
    23521 gacgaccccg cgacctcggt gaccgaccgg acgggccggc tgcacgacta cgacaacgtg
    23581 tggtcggcgg acggcgcgac gttccccttc gccgggaact tcaatcccac cctcaccatc
    23641 caggccaatg cccggcggat cgcggtcggc atctcctgac ggccgccccc tctcccctcc
    23701 cccgtacgcc ctgccgccct tccccgtggc gagccacccc cttcgtgaat cccccttcgt
    23761 gacgcgcgaa ctgtcttcga ccttggaggt atgtgtcatg cccctgcaaa gttcacggct
    23821 tgcggtcgac aacggaaccc ccgtccgcgg caagccctgg ccggtgtggc cgcagcccac
    23881 cgacggcacc ctcgacgccc tctcccgcgt cctgcgttcc ggccgctggg ccatcagcgg
    23941 cccctaccgg ggcgtggagt cggccgaacg ccgcttcgcc cgccggttcg ccgactacca
    24001 ccgcatcgcc cactgcgtgc ccgcctccag cggtacggcg agcctgatgc tggccctgga
    24061 ggcctgtggc gtcggcgcgg gagacgaggt catcctgccc ggcgtcacct gggtcgcctc
    24121 cgcctccacg gtggtgggcg tcaacgcggt gccggtgttc gccgacatcg acccggacac
    24181 cctctgcctc gacccggacg ccgtcgaggc ggccatcacc ccggccacca aggcgatcgt
    24241 cgtcgtccac ctctacgcgg ccgtcgccga cctcacccgc ctcaaggagg tggccgaccg
    24301 gcacggcatc gtgctcatcg aggactgcgc gcaggcccac ggcgccgagt tcgaaggcca
    24361 caaggtcggc accttcggcg cggtcggcac cttcagcatg cagcagagca aggtcctgac
    24421 cagcggcgag ggcggcgccg ccatcaccgc cgacccggtg ctcgcccgcc ggatggaaca
    24481 cctgcgcgcg gacggccgct gctaccgcga tcaggcgccg ccctccggcc acatggagct
    24541 cgtcgagacg ggcgagctga tgggcagcaa ccgctgcatc tccgagttcc aggcagcggt
    24601 cctgaccgag cagctgggcg aactcgaccg gttcaacgcc ctgcgacggc acaacgcgga
    24661 actcctcgac gcgctgctga ccgacgtcgg ataccgcccg cagcgcagca cgcccggcac
    24721 caccgcccgc acgtactaca cctacgtcgc cgagctgccc gacgcggaac tgcccggcgc
    24781 ggacatcacc aaggtcaccg aggcgctgac cgccgaactc ggcttcccgg tggcaccggc
    24841 ctactcgccg ctcaacgcca accccctgta cgacccggcc agtcgcagcc ggttcgccct
    24901 cggaccgcag cacgagaagc tcatcgaccc cgcccgattc gtgctcccgg tgagcggccg
    24961 cctgacgcgt cggctcgtca ccttccacca cgccgccctg ctcggcgacg agtcggacat
    25021 gagggacatc gcggaagcgt tcaccaaggt gctccagcac cgggccgtcc tggccgcttg
    25081 agccgaagcc gtcacacacg ccttcaggat tggggacaga ccatgcaggt caccaccatc
    25141 acgatggatg acgtccagta tccctaccga ttaggcacgg actgcctcga cggcatcgtc
    25201 acgcgcctcg gcgaactcgg cgccagccgc tacctgatcg tcagcgaccc cagggtcgcc
    25261 gagctgtacg ggcaggggct gcgcgaacgg ctcgcggagc aggcgggacc cgccgagctg
    25321 atcacccatg cctcgggaga acagaacaag ggcctgcccg cactgcacga cctggccgag
    25381 gaggcgctgc ggcgcggcgc cgaccggcag agcatcgtcg tagcactcgg cggcggtgtc
    25441 accgggaaca tcgcggggct gctggccgcg ctgctcttcc gcggcatccg tctggtgcac
    25501 gtgcccacca ccgtggtggc catgctggat tcggtgctct cgctcaagca ggccgtgaac
    25561 gcgggagtcg gcaagaacct ggtcggcacc ttctaccagc ccgtcgaagt gctcgccgac
    25621 accgcgatgc tgcgcaccct gccggtccgc gaggtcaggt cggggatgtg cgaggtggtg
    25681 aagaactcgc tcgccatccg ccccagcatg atcgaccagc tgtcggccgg gctgcgcccc
    25741 gacggccgct atcccgacga cacgatgcac tggatcatct acgagagcct ggccgccaag
    25801 gcccaggtca cggcgtacga caagtacgag cgcggcgagg gactcatcct ggagtacggg
    25861 cacaccgtcg ggcacgccgt ggagcactcc tcgcagggag ccgtgccgca cggcgccgcc
    25921 gtcgcgctcg gcatgatcgc cgccgcccag gtctcccacc gggcgggctg ggcctcggcc
    25981 gaactcgtcg acctgcaccg ggagctcgtc gccaagaccg gggtcgcgcg gcgcatcccg
    26041 tccgacatac cgctctccgc cgtcaggcac cgcctctcct tcgacaacaa gcggggctac
    26101 ctcccggcct ccgccgacac ctatccgatg gtgctgctcg aatcccccgg caaggtgctg
    26161 cgcagcgagg gcaccgtcct gacggcggcg ccacgggacc tggtcgacgc ggtggtcgac
    26221 gaactcgcgg aacccccacg gcccgcggcc gcgaggaccg acgacgccgc caccgtcctc
    26281 ggcggtgccg ggtgagcgcc cccgtgcgcg tcggcgtcgt cggtgcgggg ttcatgggcg
    26341 gggtgcacgc cgaggtggtg gcggctcatc ccggcgcccg gctcgaagcg gtgcacgacc
    26401 tcgaccccgc cgccgccagg gacctggccg agcggttccg cgccgagcgg gccgagccct
    26461 cctgggcgga cctgctcgcc gaccccgcga tcgacctgct catcatcacc acgcccaacg
    26521 ggctgcacca ccggcaggcg gccgaggcgc tgcgggcggg caagcacgta ctggtggaga
    26581 agccgctcgg tgtcacgccg gagcaggtgg ccgagctcgt cgaactcgcc ggacggcacg
    26641 accgggtcct tgcccacgga agcaacttcg tgcacagccc gaagttcgtc cgggcccgtc
    26701 aactggtcgc ggacaccgag gcgttcggac ggccgcacct ggtccgggtc gtcttccgca
    26761 actcgggccc cgaggccgcc tgggccgcgt ccaaggacct cgcgggcggc ggagccctcc
    26821 tggacctggg ctgtcacgcg gtggagctgt gccggtggct gctcgacggc gccgacgtcg
    26881 agtcggtcag cgcccgactg cagcgggtgc ggccgcccca cgacgccgaa gcggaccgcg
    26941 cgtccggcac cgcgggaacc gcgcgggtcg cgctggagga ccaggcgctg ctggtcatgg
    27001 agttcgccga cggcgcggtc gggcagtgcg acgtctcctg ggtcacccag ggcggtgagc
    27061 aggtcaccgc ggagatcatc ggcaccaagg gcagggtcga ggtcgacctg tggaccggca
    27121 tggggctgcg cgcctactcg gacaagggct atcaggacgt ctgggatccc gagcagggct
    27181 gggtgcatcc ggaatgggag tggatccggg cgagcggcta ctaccaccag gacggcaccg
    27241 tgatcgaggc ggtgggccag ggcatccccc tcacccacgg ccccgcggaa gcgctcgcct
    27301 cggcccgtgt cctggccacc ggttaccgca gtcacgcgga ggggcgggta ctgcggctgt
    27361 ccggcgcgcc ggtcggccct ggcgcgtcga cgacggcggc gggctcggaa tgaccgccac
    27421 cgagctcggg gcgaccgccg acaccgccgg gctccggaag accgccgacg ccaccgggct
    27481 cgggatgacc gcccggggcc gcggccgacc cgccgcggtg cctcgtccgt acctcgtccg
    27541 cacctcaccg atggagggac catgaccgag cctgccaagg gtgtgctcgc gctgactccg
    27601 ttctttctgt actcggagta ccaggaccac tgggatccca agttcgaccc catgggcggc
    27661 atgcacctgc tggtgcgggc cctggtcgag gagatggcgg gccgcggcgt cccgcaccgg
    27721 gtcctgacga tgtcaccgcc caaggtgccc aaggacatca ggatcgggca gcggatcaag
    27781 gtgcacgccc ggcggctgcc cgtgctgccc atcccctccg acctggaggg gtacttcgga
    27841 ctcgtcggcg cctgggccaa gggcagcctg ttgtgggtgc tgcgcaaccg caagcggctg
    27901 cgccgggaga tcggcgcggt gcacgcgcac tgcgacggct cgggcgccgc ggccttctac
    27961 ccgtatctga tgtcccggat cctcggcgtg ccgctggtgg tccagatcca ctccagccgc
    28021 tatctgagcc agcaccccac cacgctcttc gagcgggtga ccgacccgat cgccaagtgg
    28081 gcggagcggc acgccgtccg caaggccgcc gcggtcctga tgctcaccga ccgggcccgc
    28141 gacgagatgc ggcgcaaggc ccagctgccc gcggagcgcg tgcaccggct cgcgtacctg
    28201 gccagcgacc agttcaagga cgccgacacc gaggcgaggc gggcggaact gcgggagcgc
    28261 tacggcctcg acgaccgccc gatcgtgctc tacgtggggc ggatcgccgc cgagaagggc
    28321 gtggagtact acatcgaggc cgcggccgaa ctgacccgca ggggccggga ctgccagttc
    28381 gtcatcgccg gggacggtcc cgcccggccg gacctcgaaa agctgatcgg cgcccgcggg
    28441 ctgcgcgacc gggtgaccat cacgggcttc atgtcccacg agttcatccc atccatgatc
    28501 tccctgggcg aactcgtggt gctgccgtcc cggtacgagg agctgggcat cgtcatcctg
    28561 gagtgcatga ccatgcgcag gccgctggtc gcgcacgacg tgaacggcgt caacaagctc
    28621 atcgaggacg gcaccaccgg aatcgtcgta cccccgttca ggaccccgga gatggccgac
    28681 gccgtcgagc ggctcctcga cgatccggag ctgcgcgagc ggatggcgga gaacgccgcc
    28741 ccgctgcccg ccgccaagta ctcgctctcc gcggcgggcg accaactggc gggcatctac
    28801 cgggagatcg ggctgtgagg gtcctcctcg tctcccccca ccccgacgac atcgcgctgt
    28861 ccttcggcgg ctgggtcgcg gcccacgccc gcgggctcgc ggccaagggc tggcggttcg
    28921 acctgctgac cgtcttcggc acgaccctgt acgcgcccca cagcccgcgc gccgtcacca
    28981 aggaggccat cagcacgctc cgggagcgcg aggaccgcga ctacgcgcgc cgtcacgggc
    29041 tgcggctgac ctctctccgg caggaggact gctcctgcct gggcatggac gacgaggagg
    29101 agctcatcgc ccccgaggcg accgatcctc gccgggccgc cgtgcggcag ctgatcgcgg
    29161 cggcgctcgc cggggccgac ctggtcgtcg cgccgctggc tgtcggcggc cacgtggatc
    29221 accgcatcgt ccgcaccgcg gtgcggcagt cgctcggcgc caccccctgc ctctggtacg
    29281 aggacctgcc gtacgcgttg gagagccccg tcgaggtgcc ctccgaccac cggccctggc
    29341 tggtcgacat cagggggcac gaggcggcca agcgcgccga tctcgcgctg taccgctcgc
    29401 agatgaccgc cgccgacacc tccgaggtcc tctcgtaccg gccggacggc gcgtccgtcc
    29461 cgtgcgagcg gctctggagt tcggcgggct tcccccagga cctggccgag cggatggcac
    29521 tggccacgct ggccgccgtg acacccgaca aggagtcgct atgagcaaga agctggcgct
    29581 gttcggcgga actcccgtac ggaacgagga gttctacgac ggcccgcaca tcgggccgca
    29641 cgatctcgac cgcctcaaat ccgtcctcga ctcggggaac ttcggcggca tccccttccc
    29701 caacacccac cacaccgcct tcgccgacct gttcaccggc aagctcggcg ccccgtacgg
    29761 cctgatggtc tccaacggca ccatcagtct ctccatcgcg ctgcgcgccc tgggcgtgcg
    29821 tgccggggac gaggtgatca ccaccggcta cacctggatg ggcacggccg cggcgatcgt
    29881 gcacatcaac gccgtccccg tcctggtgga catcgacccc acgacctggt gcatcgaccc
    29941 ggcggcggtg gaggcggcga tcaccccgcg caccaaggtg atcgtcccgg tccatctggg
    30001 caatcagatc gccgacctcg acgcgctgcg ggcgatcgcc gacaagcacg gactcgcgat
    30061 cctggaggac accgcgcacg ggcacttcgc cgagtggcgg gggcagtgcg tgggcaccca
    30121 cggggacgcg ggcagcttca gcttcgagag cagcaagatc atgactgccg gtgagggcgg
    30181 cttcctggtg gccagggacg aggacgtgta ccagcggatg atgtcgctgg ccaactgcgg
    30241 ccgcaaggag ccgggttacg acggtttcgc gggccgcacc ctgggctgga acgcccgcgc
    30301 gagcgaactg caggccgcct tcatgatcgg gcaggtcgag cagcacgacg cgctgcacgc
    30361 caagcgggcg gcgagcgcgg cgaagctcac cgcggggctc gccgagatcg gcggcttcac
    30421 tcccgtgggg aacgacgacc cgaggatcac ccggcgccag tactacgagg tcatctaccg
    30481 cttcgacccc gccgcctggg aggggctgca ccgggacgag gtcctctcgg cgatccttgc
    30541 cgagggcatc gagctggagg gcgacgcctt ctacccgccc gtacacaaga gcgaactgtt
    30601 cgcggtggac gccgtccact ggcccatgat cgccgagagg tacggcgatc ggatcggccc
    30661 ggacagcgtc gacctgcccg tcgccgaccg cgccgccgcc gacgagtccg tgtgggtgca
    30721 ccacgcgctg ctcaccggcg acgacaagga cctcggcgac atcctcgaag ccgtcgccaa
    30781 ggtccgcgac aacctgcgag aactgcacga cgcgagctga cctgacggac cccgcagggg
    30841 cggcggtgtg ccgcgccgcg cccccgggtg tgccccgtcc cgcccacccc gggcgtgccc
    30901 cgtcgcgccc accccgcccc cggcgtctcg tcaccccctc cccccccctc atcagcccct
    30961 gagaagggaa gaccagccat ggcccttgcc gctccgcccg gcgaactgac cctcgccctc
    31021 acaccggacg acaagaccct cgatcccgcc tcgctcgacc gcgcgctcgc catactcgcc
    31081 gagcacggca tcctggtgct gaccgggatg ctcaggaccc ggctcaccga tcagctgcgc
    31141 acggcgatgc tcgacgacct gcccgaggtg ctgcggcagc aggacgtgcc cacgaacttc
    31201 gtgccaggac acgtccaaca ggacccgccg gtacgggagt cgttgctctt ccccgacgtg
    31261 ctgctcaacc cggtggtcta ccagatcacc catgccgtgc tcggcgcgga cgcccgcaac
    31321 gccgtctaca gcggcaacat gaacctgccg ggcagccacg agcagccggt ccacctggac
    31381 gagccgcacc tgtggccggg catcagccac cccccgtact gcctctgcgt cgacgtcccc
    31441 ctgatcgact tcacgctgga gaacggcagc accgagtact ggcccggctc ccacgtcctc
    31501 aaccccgacg agtgctacga cgagcggggc tgtgtgctgc ccgccgagct ggagcggcgc
    31561 cgggccgtcg cgccgccggt ccgcttcccc atccccgtcg gctcggtcgt catccgcgac
    31621 ggcaggctgt ggcaccgcgg cgtacccaat ctgagcgcgg ccccccggcc cctgctggcg
    31681 atgacccact acacagagtg gttcgacatg ccgccgatcc agctgcccga caccgtcaag
    31741 tcctgggtcg acggctccga tcggcacacc cacgcgcact tcgtggcggg cgacgtggat
    31801 cacctgacgg gtgatcatcc cttcgccgtc cgctgacgac gacggcggcc gacggcgcgc
    31861 cgtgagcagt caactcgctc tgcgggggcc cgagttatcg gccaatcttt gcaaacctga
    31921 ggaggacact ttgcgggttc ttgtcaccgg aggctccggc aacgtcggtg tgggtgtcgt
    31981 cagggcactc aacgccgccc gccatcacgt cgtggtggcc agccgcggct acagccccgc
    32041 gctcctgccc gaaggcgtac gcgccgtacg cctggagcgc accgagcccg acgcctacac
    32101 caggctggtc gccgccgaaa agcccgacgc cgtgatcgat ctgacctgcc acgacgccgc
    32161 ggacgcggcg gtcaccctgc gggcctgcgc cggggtcgac cgcgtcgtgg tcgtctcctc
    32221 ggtgacggcc gccgggcccg ccaccaccac tccggtcacc gaggcgacag cggcaccgcc
    32281 gctctccgag tacggcatcg acaagctggc cgtcgaggag acggtgcgcg ccgcctgggc
    32341 ggacggcacc tcccaggccc tgctcgtgcg cctgggcgcg gtctaccggc tcggcgcgga
    32401 tctggacggc caactcgccg aggacggctg ctggctggcg cacgcggcgg ccggagcgcc
    32461 tgccgtgctc gccgacgacg gcgcggcgcg gtggaacctg ctgcacgccg acgacgcggg
    32521 cgccgcactc gccgaactgc tggccaacga ccgcgctcgc ggcgtcctgg tccacctggc
    32581 ctcccggcat ccgctgccct ggcgcgagct gtacgagcgg gtccaccacg cgctcggacg
    32641 ccccttcaac ccggtttccg tacccgcgga gtgggccgcc gagcagctgg aggacgccga
    32701 gttcctcgcc gagacctccc gctgggacca ggtcttcgac ctcggcctgc tcgaccggct
    32761 cgcgccgtcc taccaggagc gcggcggacc gtcgcgcgtc accgaggtcg ccctgtggct
    32821 gatccgccag gggcgcgtcg gggacgcgga actcggcgcg gagatacagg agttgcccgc
    32881 gcgcctcgcg gccgtgcgca ccgcgccagg gctggtgtga tttcggccga tgtgatcgtt
    32941 ccgcatgatc ccggcttccg aagatcagtt acgttcctcg tcacgggagg ggcgggctca
    33001 ccgtccgccc cgaccggcgc gttcacccca tggagaggat ggcccatgtc gcagtccgcg
    33061 tccgacgagg accccaagtt aacgcgagtc gtggaggcgg tccggggcgg caggcggtat
    33121 cggagcgtga ccgaccaggc cgttcgccga ctggccagag cggcactcgc tgtggagggc
    33181 ggcgacgtca ccagggccac caagcggacc aagcgcggac tccacgaggt cttcggcgcc
    33241 ttcatgccga tgacgcccaa gtacgaggcg ctgctgcgcg atgtgcggga ggccgtcgag
    33301 ctcgatgacc cggaggcgat ccgcaccgcc ctgaaacccg ccctcggcgc ccactcctcc
    33361 accagggagc ggctccccat cctcacggaa atgtacgccg aggtcttcga ccgcctcgac
    33421 accgcccccg ccaccgtgcg cgacctggcc tgcgggatga acccgctgac cgtcccctgg
    33481 atgccgctgc ccgccgggac gacctacctc gcctccgaca tcgaccaccg tctgatggac
    33541 ttcgcgggaa cggtgctcac cgctctcgga gtccccaacc gggtagaggt gcgggacctg
    33601 ttgacggacc cggatcccga accggccgac gtcaccttcc tgttcaaggc cgtcccctgc
    33661 cttgaggcac agggcaaggg cctcggctgg aagctgctcg accagatcaa ttcccccgtc
    33721 ctggtggtga gtttccccac caagaccctg ggccgccgct ccaggggcat gtaccagacc
    33781 cattccgcgg aattcgcccg gcgcgtcgcc gaacggccct ggaagtgcga cgagatcgag
    33841 ttcggcgacg aactcgtcta cgtggtcacg aagggctgac gacgggcagg agccgttccc
    33901 acgaggcgag ggcgccggac cagaacccat tgggctgaac taggcaagat ggaggtacag
    33961 cgtgcgcgta ctccggctca ccccgttcta ccaccacgac tgtgtggaca gctggcccgc
    34021 cgagttcgac gcggtgggcg gcatgcaggt acagatcctg cggatgtccc gcgccctggc
    34081 cgagttgggg gtgcgccagc aggtgctcac cgtcggcttc cccggtctgc ccagagtgcg
    34141 gcgcgactcc gagaacctgg tggtgcggat caccagggcc ccgctgccca ggctgcgctc
    34201 caggatcacc ggcctggtcg gcctcaacca ggcgtggctg gccgccgcgc tcaccgaatg
    34261 cgtgaaactg cggcgccgct ggcccgccga cctgatccag gtccatctgg acggccagct
    34321 ctgggcgttg ctcgcgggac cggtcgccgc ccgcctggtg ggcgtgccgt acacggtcac
    34381 cgtgcactgc tcgcggctgg cggtgtatca gcccatgtcc accgtcgacc gcatccagca
    34441 ccccttggtg accgccgtcg agcgctgggc gctgcgccgt gcggccggga tcaccacgct
    34501 gaccgagcgg accgccacgg tgctcgccgc cgaactgggc gcggcccaga gggtgatcga
    34561 cgtggtgccc gacgcggtcg accccgatcg ggccgaggcc gcgcccgccg aggtcgagcg
    34621 gctgaagaag cgtttcggcc tgccgcagga gggcggtccc gtcatcggat tcgtcggccg
    34681 gatcgcccac gagaagggct ggcgccacgc cgtccaggcg gtggccgaac tcgcggacgc
    34741 gggccgggac ttcaccttcc tcgtcgtcgg agacggaccg cagcgggccg acatggaggc
    34801 ggcggtggcc gaggccggtc tcaccgaccg gttcgtcttc accgggttcc tgcccaacga
    34861 cgagatcccc gccgtgatga ccgccctgga cgtcctcctg atgccgtccg tgcacgagga
    34921 gttgggcggc agcgccgtcg aggccatgct cgcgggaacg ccggtggccg cctacggggt
    34981 cggcggcctg tgcgacaccg tgggcaaggt gaccccgtcc ttgctggccg cgcccggcca
    35041 ggtggccgaa ctcgcgcgga cggtcaagcg ggtactcgac gatcccgcgc cggtcctggc
    35101 cgaattgcgt gccggacggg agtggctcgc ggacgagttc ggtgtccacc acgcggccgg
    35161 tctcgcgttg gcccactatg agcgggtact cggcaaagaa cggtagccgt acgacacccg
    35221 acgtcctgtt cgacttgttc tacgacagct gatctggagt atgcgtgagg caggactggc
    35281 agcacttgga cgagtccgac gtacgggtcc gaccgggacg gcgtagttcc cgcccgcgca
    35341 gcaagaaccg ccccgagcac gccgacgccc ggtccgccat ggtggtcggg gtcgatcgcg
    35401 gccggtggac ctgcgtcctg gactccgacc ccgagagccg gatcaccgcg atgcgcgccc
    35461 gcgaactggg ccgcaagtcg gcggtgatag gcgaccgcgt cgacgtgatc ggcgacctgt
    35521 ccggcaagcc gggcaccctg gcccgcatgg tccgggtcgc ccggcgcgac agcgtcctgc
    35581 ggcgcaccgc cgacgacacg gacccctacg agcgggtggt ggtcgccaac gcggaacagc
    35641 tggtgatcgt ctgcgcgttg gcggcgccgc agccgcgcgc cggtttcatc gaccgtgccc
    35701 tggtggcggc ctacgcgggc ggtctgcggc cggtgctctg cctgaccaag gcggacctga
    35761 agggccccga ggacgtggtg agcacctacg cccatctgga tctgccgatc gtggtcacgc
    35821 gctccgaccg cgccccggac gccctgcgcg agcagctggc cgggcgcgtc tcggccctgg
    35881 tcggacactc cggagtcggc aagtccacgc tgatcaacat cctgatcccg caggcccggc
    35941 gggtcaccgg tgaagtgagc gcgatcggga agggccgcca cacgtccacc tcggccgtcg
    36001 ccctgccgct gccggacggc ggctgggccg tggacacccc cggcatccgc tccttcgggc
    36061 ttgcccacgt cacgtccgac gacgtcctcg acgccttccc cgacctgagc gacggcgcgg
    36121 aggactgccc gtccggctgc cgtcatctgg gcgccccgca cgactcggga tgcggcctgg
    36181 agcgcctgag cgaagccgat ccggccaggg cgcggcggct ggagtcgctg cgccgcctgc
    36241 tgcgctcgca cgcgggcatc gaagaggagt gaccaccgtg accacctcgt ggtccaccat
    36301 ggggacatga gccgactgac ccacatcagc gcccccgagg gcgtcgcccc cgccaccgcc
    36361 tacacccacg tcgtgatggg cacgggccga ttcgtcgcga tatccggcca gttggccctg
    36421 gacgaggacg gcaagctggt cggcgagggc gacgcggcgg cgcaggccca ccaggtcttc
    36481 gagaacctgc ggcgctgcct gaccgcggcg ggcgcgacgt tcgacgacgt cgtgaagctg
    36541 acgtacttcg tgacggacat ggcgcacatg cgggcgatcc gcggcgcgcg ggacgccttc
    36601 cttgaccccg agcggctgcc cgcttcctcg gcggtgcagg tgggcgcgct ggtcgcgccc
    36661 gagtatctga tggagatcga ggcgttcgcg gtggtggccg agtaggcgcg cgccgaccgc
    36721 ccccgacctc actccggcag ccgcgccagg gccgccgagg ccgccgccgc gaggcgggga
    36781 tgggcccgcg ccgcggtcag caccggtctc gcccgggggt ccccgagcgc gcccaggccc
    36841 tccacacagg cgagcgcgat cttgccgaac gggtcgtgcg gggcgaggcg ccgccgcagc
    36901 gtcgtgatca gcgcgggcgc cgactccggg gcgcgcagct ccgtcaggag gcgcaccggg
    36961 tgcagggcgt aggcgacgcg gagttcgttc gtcgccaggg cggccgccgc gcgcgcggtg
    37021 cgggggtcgc cgagcctggc cagggcgtac gccgccgccg cgcagcgcgg cgcgtcccgg
    37081 tggttgagga gcaggacgag cgattcgaag gcccggcggt ccccggcgac gccgagcagg
    37141 accgccgcca actcccttgt ccacaagggc tgtcccggcg agacgagcac ctcggcgagc
    37201 tcctcgaggt caccggtcgc gaccagccgc tcgtactcct tcgagccccc cgcctcggcg
    37261 cgtaaacgtt ccgtcaccgt ccgcaactcc tcatccatgg ccgcgagcct aaccgccgat
    37321 ccctcccggc gacgtagatc acaaacactg agggctggcg cgctcgttac tcgccggtta
    37381 atctcatgtg agcggggcac actccccgta gcacctccct ttcccgcggt ggcctggtga
    37441 cgcagccact gtgggcagct tgtcggttcg gtacttcagg taccgctgca ccacctcgta
    37501 cgacgtggct ccgggacaga gcccgtcggc ttctcaccgg gcgtgccctt cgcgccgccc
    37561 ggacacgaca cgcaccactt tccgcacgcc gtacggcagt tgccgcctgc gcgtgcgccc
    37621 ctcagtcgtc actctcttcc tggagtccac gcatggacgc tcccttgaac accgtcgccg
    37681 tcatcggtct gggcacgatg ggcaccggca tcgccgaggt cctggcccgc gcgggccgcg
    37741 aggtcatcgg catcgacatc agccaggcgg cggccacccg ggcggtgacg gccctggaga
    37801 cctccacggc ccgcgcggtg cggcgcgagc gcctcaccga tgaggagcgg cgcggcatcc
    37861 tggcccgctt ccgcaccttc accgatctgc aggccgcggc cgacgtcgac ctggtgatcg
    37921 aggtcgtccc cgagtcgtac gagatcaagc agcggatcgt gcgtgaactc gacgccgtgg
    37981 tccgccccga gacgatcatc gcgaccggca ccaacgcgct gtccgtcacc cggctcgccg
    38041 ccgagtcggc gcgccccgag cgcgtgctcg gcctgcactt cttcaacccc gcgcccgcga
    38101 tgaagctcgt cgagatcgtc tcgtccgtgc tcaccgcgcc cgccgccgtc gccgcggtca
    38161 ccgagctcgc gtacgccctg ggcaaggagc ccgtcgcggt cggcgaccgg cccggcttcg
    38221 tcgccgacgg gctgctcttc ggctacctca accaggccgc cgcgatgtac gaggcgaagt
    38281 acgcctcccg cgaggacatc gacgccgcga tgaagctggg ctgcggcctg ccgatgggcc
    38341 cgctcgcgct gctcgacctg atcggcgtgg acaccgcccg cacggtcctc gacgccatgt
    38401 acgccgagtc ccacgaccgc ctgcacgccc ccgcgccggt cctcaagcag ctcagcgagg
    38461 cgggcctgac cgggcgcaag tcggggcgcg gcttctacac gtacgccgag ccgggcagca
    38521 cggaggtggt gcgcgacgcg ctgaccccgc cggagggcga gcggagcgtc ccgagccgtg
    38581 ccgtgcgcgc ggtcggtgtg gcgggctccg gcacgatggc gtccggcatc gccgaggtct
    38641 tcgccaaggc gggctacgac gtggtgctcg ccgcacgcag cgaggagaag gcgcagctcg
    38701 ccagggcccg tatcggcaag tccctcgcgc gctcggtgga gaaggggcgg atcaccgccg
    38761 agtcggcggc ggagaccctg gagcggatca ccccggccgg ttcgtacgag gcgttcgccg
    38821 atgtcgatct ggccctggag gccatcgcgg aggacctgga cgtcaagcag cagctgttcg
    38881 cgacgctcga caaggtctgc aagcccggcg cgatcctggc gaccacgacg tcctcgctgc
    38941 cggtcgtcgc ctgcgcccgc gccacctcgc gcccgcgtga cgtgatcggc atgcacttct
    39001 tcaacccggc cccggcgatg aagctggtcg aggtggtgcg caccgtgctg acctcggacg
    39061 aggtgcacgc caccgtccgt gaggtctgcg cggcgatccg caagcacccg gtggactgcg
    39121 gcgaccgcgc gggcttcatc gtgaacgcgc tgctcttccc gtacctgaac aacgcgatca
    39181 agatggtcca ggagcactac gccacgctgg acgacatcga cgccgcgatg aagctgggcg
    39241 gcggctaccc catggggccc ttcgagctcc tcgacgtggt cggcctcgat gtctcgctcg
    39301 ccatcgagaa ggtcctgcac cgcgagttcc gcgacccggg cctggccccg gcgccgctgc
    39361 tcgaacacct ggtggccgcg ggctgcctcg gccgcaagac ggggcgtggc ttccgcgaat
    39421 atgcccggcg ctgagccggc cgaggaccgc ctggactccg cgacggactg gggcgggctg
    39481 ctcgaaccct cgggcggccc tctcccacac gagcaccgtg ctgcgcatat gcagtacgtt
    39541 cgtggcatgt ccaaggccgc caagtcctca cgcaacgcca gccccgacgc tccggagagc
    39601 gccgcgggca gccgtgccgc cgcccaacgc ctcaagatgc gcagggagct ggctgcggcg
    39661 gccatggagc tcttcgcgac caaggggtac gaggcgacga cggtcgacga gatcgccgcc
    39721 gccgcgggcg tcgcccgccg gaccttcttc cggcacttcc gctccaagga agaggcgatc
    39781 ttccccgacc acgacgacac cctggtccgc gcggaggagg tgctgaacgc cgcaccggcg
    39841 cacgagcacc cgctcgacac ggtgtgccgc ggcatcaagg aagtcatgaa gatgtacgcg
    39901 gcctcgcccg cggtctccgt ggagcgctac cggctgaccc gtgaggtgcc cacgctgcgc
    39961 gagcgcgaga tcgcctccgt ggcccgctac gaacggctgt tcacgcggta tctgctcggc
    40021 cacttcgatg agcaggcgca ccacgacggc aacgacgacc cgctgctcgc cgaggtcgcc
    40081 gcctccgcgg tggtcaccgc ccacaaccac gtcctgcgcc gctggctgcg ggcgggcggc
    40141 cagggcgacc tggaggccca cctgaaccac gcgttcggca tcgtccggct caccttcggc
    40201 accgggatcg gcgcgggccg ctcctcggca ccggccaccg cccccgccac ggtctccgcg
    40261 cagggcgagg tcctggtcac cgtggcccgt acggacgcgc cgctcgacga ggtcatgcgg
    40321 acgatcgaga aagccctccg cgagcgggcc tcatagtccg cttttcgacc gattcgtcct
    40381 tggcttttca gggggcgcta cccgccggta gcgccaccct tcggcatgcc gctaccccct
    40441 ctgacctgca ctgatcgatc atcggtcaaa aactcatggc actcagtgcc ttgccccttg
    40501 gcacctggtg tcatacgttg atgttgtccg ggcggccggc gtgcagagat catccggtac
    40561 gtcggctgtc ccctcaagcc cacggcttgt acgcccggac gcctgcgtca caggcacctc
    40621 tcgcgcccca ccacggcgcc gccgagcacc cacccttcgc cgaaccgacg gcacacctcc
    40681 acccagcacc acaagcaccc cgacgtatcc ctcaagacag cgctcccgca gggcgcttct
    40741 tcgccggagg catcaccgtg aaggaaatcc tggacgcgat tcagtcgcag gacgcacagt
    40801 ccgccgactt cgccgctctc cccctgcccg actcgtaccg cgcgatcacc gtgcacaagg
    40861 acgagacgga gatgttcgcg ggcctggaca cccgcgacaa ggacccccgc aagtccctcc
    40921 acctggacga cgtgccggtg cccgaactcg gccccggtga agccctggtg gccgtgatgg
    40981 cctcctcggt gaactacaac tccgtgtgga cctcgatctt cgagccgctg tcgaccttcg
    41041 gcttcctgga gcgctacggc aaggtcagcg agctcaccaa gcgccacgac ctgccgtacc
    41101 acgtcatcgg ctccgacctg gcgggcgtcg tgctgcgcac cgggcccggc gtgaactcct
    41161 ggaagccggg cgacgaggtc gtcgcgcact gcctgagcgt cgagttggag tcgagcgacg
    41221 gccacaacga cacgatgctc gaccccgagc agcgcatctg gggcttcgag acgaacttcg
    41281 gcggcctcgc cgagatcgcg ctcgtcaagt ccaaccagct catgcccaag ccgggccacc
    41341 tgagttggga ggaggccgcc gctcccgggc tcgtgaactc caccgcgtac cgccagctcg
    41401 tctcgcgcaa cggcgccgac atgaagcagg gcgacaacgt gctgatctgg ggcgcgagcg
    41461 gcggactcgg ctcctacgcc acgcagttcg cgctcgccgg cggcgccaac ccgatctgtg
    41521 tggtctccag cgagcagaag gccgacatct gccgctccat gggcgccgag gcgatc
//
