LOCUS       BGC0000709             50466 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptomyces fradiae neomycin biosynthesis gene cluster, strain DSM
            40063.
ACCESSION   BGC0000709
VERSION     BGC0000709
KEYWORDS    .
SOURCE      Streptomyces fradiae ATCC 10745 = DSM 40063
  ORGANISM  Streptomyces fradiae ATCC 10745 = DSM 40063
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:05:23
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             <1..1635
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFF6"
                     /note="ORF SfrA10.1; partial reading frame"
                     /product="hypothetical protein"
                     /protein_id="CAF33300.1"
                     /transl_table=11
                     /translation="MLKSVANGIRQGDTRLSLLMGSGAAEEAYGLRFSRTLVKVLREGL
                     PSAGGTLAPEAVVEAVRGDGGTVGQTILRAEFDGSRFAPGPLWLARNARHPAAAGSLLG
                     PVGAQELARAVRAVDESLLPASVTSAPDVAKVRDGLAAAPWSPARQWALDVVDALDTGA
                     RTVGLLGSWPGTPLTSSVLRRTFTAACPGPVESPPASSGTDLLRDAVEYLLLRAPLAGR
                     RRVAPLVDFVALLAHETGVGPQTPELRGWAAGIGALIDLNDAFDRLADRRRDMRLRLVV
                     SLHAAVGDEWPESLEAWLLDDGEVRDREEFACSPDRAGVERQLGAALRWASRLAARMDV
                     PLRRVEVAAPAPLLVQWRPEETDFGMRLGAEHDVVLRWSDRIRPPEHLWWINDHARRTL
                     SALESGPGGTRLEWLGESDTRQVRELRERLLGGPRTRAVALEHRPAHLRDMLETLLASS
                     PIVLWPDDEAHRVPDEARRYLDAHWHLLPGEFCRAYRDGWGGPADRSAGRPGRGHLARL
                     RTVWDDAEWLEFCRWFEQYATDGESPA"
     source          1..50466
                     /db_xref="taxon:1319510"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces fradiae ATCC 10745 = DSM 40063"
                     /strain="DSM 40063"
     subregion       1..50466
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000709"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..50466
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="2dos"
                     /region_number="1"
                     /rules="((DOIS or DHQ_synthase or ValA or salQ) and
                     DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             1632..2567
                     /codon_start=1
                     /db_xref="GOA:Q4A4A8"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011704"
                     /db_xref="UniProtKB/TrEMBL:Q4A4A8"
                     /note="ORF SfrA10.2"
                     /product="putative ATPase"
                     /protein_id="CAF33301.1"
                     /transl_table=11
                     /translation="MTWQPFYSGTGGAPRERVELAPPPPWRVFPRPSLHERFVPPPGLV
                     EAVNAALLLRRPLLLTGPAGSGKSTVIEQVAAELELGPVLRWHITSRSGLSEALYRYDA
                     LGRIHAQRLEGAGGGDDIAPFLRMGPLGTALLPSPRPRALLVDEIDKSDLDLPSDLLDV
                     LERGEFEIPELARYGRDVVAVREWGGDARHEVTRGRVQCTEFPFIVMTSNGERDFPAAF
                     LRRCIRFTMPMPTPETLLRVVAAHLGADAAGSEAAGELVGAFVERLAGGESLAVDQLLN
                     AVHLLTGDGAPEGERRQAVVDLLLRELSRV"
     CDS             2581..7962
                     /codon_start=1
                     /db_xref="GOA:Q2MFF4"
                     /db_xref="InterPro:IPR011990"
                     /db_xref="UniProtKB/TrEMBL:Q2MFF4"
                     /note="ORF SfrA10.3"
                     /product="putative multidomain-regulator"
                     /protein_id="CAF33302.1"
                     /transl_table=11
                     /translation="MLSALRAAVPGADPAGGPGAGGALDGTGLAEALWLAAAMAGDRPS
                     GPAPAAGPVPPEEPGDAAPPPAAGDTAPRGGPGTRTPAPVVPGATAAPRAGARELHERL
                     AGAGTRVRGHAVAAPRATGLPRALEVTRALRPWKRPWPEGRRGTLDIDATVDGYARSGE
                     LLPVFSAAPERWFDLTLVVDRSPGMRVWEETLDDFTGVLDRLGAFRTLQVRDLLFDDAG
                     APRPLGQLRQADGRRLVVVVSDCAAGPWRGAAVWMLLREWAATTPTALLNPLPTKLWRR
                     GGLDLPTVRFTPAAPGAHRSRVPHEAPPALGLAAPGGPGSPSDGARGGAAVGPAGTGAG
                     AGTGPGSGVRDGAGDGDGWLPVPVLSLSPHSLDRWSRAAMRGAPEGCTAVLVPPGGRLS
                     GRPRPRTAAPSSAAAARGFLRTASPRAVRLGVLCAPFDRLSLRLLHVIRRELVPDATTA
                     DVAEAVTSGLFELVPPAGADGSLELVLSEEVRAVLRERLPAHEAWRVHQALDRHVASRS
                     GGRPGLRSVAYDTAGPRELAAERAAFARASRQTLELLGLAEPGGGAPVGAGRGAPGDGG
                     AEARDVGARDSGALRVNASSMDAAPRVDAPGVDAPDAARGARDPAADGASRGPVEAGST
                     ASEGGGEAGSPDGARAGTDGVEGGFPPPPEVFAGRADIVDSVRSRLIHPAGRVVWLTAA
                     GATAAVGRSALALHVAHRFPGERYFADLRGYGAHPVPVEAALHRLLTELGAPPGAGPHT
                     ARELAAGLWEAVGDRRVLLVLDDVADPDGLTALLPAVPGLSVLATTREPDVAPRYRLGH
                     LTAGEAVDVIAAWAGLGGGEDRAALREMTAGRVWSARTLRVLGSWIASGSAPPLPQLVR
                     MVRDLPAPADDEADTLLLRVRHLPAAEREALRLFALVPTGELTRTEGWALLGDGEAGRE
                     MPARLEAAGLLEPRGAGVYRMPEGVRRAVTGGGPSGARTSGAATRLARHHLSAAAALYE
                     EDRPDSALADQLRVRAAGTAVDHTLPVWLGNALAVAATAGRDGTPPAEDLADLLLLLHP
                     RGASTPYRSRFEQAARALIEAGPTGAERSAVRAAAALALAQYAAGAHGEAASTLGEVPA
                     GSWDRDAVLRGPVNRLAGRLALARGALEEAEGLLGRALDAYRTDGDRAGVAAASLDLAA
                     ALTRLGRTGEVLRAVLEAFGGYPDSVPHPLMRGGLLALEEALATAGRYGELLSAQEALR
                     AQYATEGGDRRAEGLLLTRTARTLIRLGRLGEAREAARTALGHLAGAADLEGDREEARR
                     LLAEAGGGDAGTHGARTIVALDTGGDHIAAGRALSLALAMSRGEGAIGPADHRMVVEEA
                     HCLAVLPSGAPVGELVTGLARWLPDELEAAGASPAARLAVHTGTVEERGGRIDASGLNV
                     RLAVAMTRSAEFRSLSENYPFHSTVCLSPEAFALLGGDGAGGGRRDGGPGGDRARRRDG
                     GAERDEAGRTGGAGPVAGFRVHEVSEGGRAVCFVLTPRLDLSAYDAELLMAARLFADAD
                     PDGRLMAAALRKSIDSVLDPERTGRYDPNDLDEREKSLISALLEQELRASFPGLPGFRL
                     RLFLSGHDWAFPQIWDSGICLLVRADEEHARWSVGLLRTRPGMTVAPVNRDAPSPLTTE
                     AREAVLWLHRSAPLRENLLLRLPERDRVAILAPASGADRTAELFRRVRERPVPEAALRA
                     VTRRRDNARTVREAAAVLREEGVLVVGGNRRGRELAGALRLPVPDADAYVSVRLTRRRP
                     HHAAPSIVAGGVAWVAAGPDDPLEPLPGDLPNPRRPR"
     protocluster    2947..26785
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[12946:16785]"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      12947..16785
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
     cand_cluster    2947..26785
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /kind="single"
                     /product="2dos"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             8100..8348
                     /codon_start=1
                     /db_xref="GOA:Q2MFF3"
                     /db_xref="InterPro:IPR000070"
                     /db_xref="UniProtKB/TrEMBL:Q2MFF3"
                     /note="ORF SfrA10.4"
                     /product="putative pectinesterase (possible fragmentary and
                     non-functional)"
                     /protein_id="CAF33303.1"
                     /transl_table=11
                     /translation="MGGDASPNPRVTVRDTTLGEAVKAAPWTDVGDVPWKGARFAEYRD
                     SGPGAGPAGANRPHPDPERAAGQEAGDRLGGWRPTAS"
     CDS             8501..9043
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFF2"
                     /note="ORF SfrA10.5"
                     /product="putative integral membrane protein"
                     /protein_id="CAF33304.1"
                     /transl_table=11
                     /translation="MGRPGERARTACTAGRGAGTAAPRNQAPQPGTGPRTGEMPMRRAG
                     LVAVATALTLGAAGQSWATTSTGDVAAGWGDRARLRVTWVDRTSFEGGSLAVTDRTCDG
                     RSFYATLTLHTGSGAVRSLGERHHTGGCGTRTVHRDIAATDASGVRGITMALCRATAGA
                     PGQCETRYLAANPYHGL"
     CDS             complement(8821..9117)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q4A4B2"
                     /note="ORF SfrA10.6c"
                     /product="hypothetical protein"
                     /protein_id="CAF33305.1"
                     /transl_table=11
                     /translation="MRSEGPGRPGDRRPAPAFRGLAGSRQRPWYGLAARYRVSHWPGAP
                     AVARHRAIVMPRTPLASVAAMSLWTVRVPQPPVWCRSPSERTAPEPVWRVSVA"
     gene            complement(9188..9994)
                     /gene="aphA"
     CDS             complement(9188..9994)
                     /codon_start=1
                     /db_xref="GOA:Q53U25"
                     /db_xref="HSSP:P00552"
                     /db_xref="InterPro:IPR002575"
                     /db_xref="InterPro:IPR008266"
                     /db_xref="InterPro:IPR011009"
                     /db_xref="UniProtKB/TrEMBL:Q53U25"
                     /function="neomycin resistance"
                     /gene="aphA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="resistance (resist) APH3 (Score: 377.6;
                     E-value: 2e-115)"
                     /gene_kind="other"
                     /note="ORF SfrA10.7c"
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="CAF33306.1"
                     /sec_met_domain="APH (E-value: 1.7e-37, bitscore: 120.9,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDSTLRRKYPHHEWHAVNEGDSGAFVYQLTGGPEPQPELYAKIA
                     PRAPENSAFDLSGEADRLEWLHRHGIPVPRVVERGADDTAAWLVTEAVPGVAAAEEWPE
                     HQRFAVVEAMAELARALHELPVEDCPFDRRLDAAVAEARRNVAEGLVDLDDLQEERAGW
                     TGDQLLAELDRTRPEKEDLVVCHGDLCPNNVLLDPGTCRVTGVIDVGRLGVADRHADIA
                     LAARELEIDEDPWFGPAYAERFLERYGAHRVDKEKLAFYQLLDEFF"
     misc_feature    <9188..>36346
                     /note="neomycin gene cluster; Location changed from
                     '(9117.9188)..(36346.39636)' to '<9188..>36346'"
     gene            complement(10003..11298)
                     /gene="neoG"
     CDS             complement(10003..11298)
                     /codon_start=1
                     /db_xref="InterPro:IPR009079"
                     /db_xref="UniProtKB/TrEMBL:Q53U24"
                     /function="possible regulator"
                     /gene="neoG"
                     /note="ORF SfrA10.8c; also conserved in the gene clusters
                     for the aminoglycosides hygromycin B and kanamycin;
                     possibly together with NeoH and NeoI component in a
                     regulatory system"
                     /product="possible regulator, NeoG"
                     /protein_id="CAF33307.1"
                     /transl_table=11
                     /translation="MTSDLPGNLGRVLQTAGVLLLWAAVLLRARPAARHPGQRGLWLAV
                     ACAAAALTLHLEAVSAYAAALTGSPRAVGLVKNQAGIVSAGAILHFAVHTTGSRRRTGA
                     VLATTAAVMAALLALAGLGSPHAPGHGPYPTLACPRCAAYWLLLVTVHVAACALCARVC
                     WRYGRSGPHRSVNLGLTLLGWGSASAGLYWLAHYYLMAVEGRPGGVLRLVLSAHAVLCA
                     AVLMVPTALQLRRAAGHARTVWRIWPLWRDLVEAVPHVALAGTRCRPLTLLRPQLPWRQ
                     LAYRKVIEVRDALLVLSHYTDPAVSRAARAHVARWGIPAERADAHVTACVLRGARAARL
                     AGADPDPAAEVLAADREACGLAAETAVLLRLTEAYLSPCARAFDPAGTSGTGPAGDAGR
                     TGSAGAPPPRTRMSETPTGPDERRGTASPPLP"
     misc_feature    complement(11284..11286)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(11288..11809)
                     /gene="neoH"
     CDS             complement(11288..11809)
                     /codon_start=1
                     /db_xref="InterPro:IPR006025"
                     /db_xref="UniProtKB/TrEMBL:Q53U23"
                     /function="possible regulator"
                     /gene="neoH"
                     /note="ORF SfrA10.9c; also conserved in gene clusters for
                     the aminoglycosides hygromycin B and kanamycin; possibly
                     together with NeoG and NeoI component in a regulatory
                     system"
                     /product="possible regulator, NeoH"
                     /protein_id="CAF33308.1"
                     /transl_table=11
                     /translation="MSYRIARLRRRCRPLLDQLVLPRPFSLEPLCAQLSARRGRPLHLH
                     PLPIQAAAAGTCGLWLATDTDDHIFYEQRTARPHQEHIVLHEIGHMLFDHHTVDAGPAG
                     LPGRLFGDLSPRLVRRVLGRTDYSTRQEQEAEMLATLIRTGDTAHGRCLPPDPYGKLHE
                     ALGMAGDHDL"
     gene            complement(12208..12735)
                     /gene="neoI"
     CDS             complement(12208..12735)
                     /codon_start=1
                     /db_xref="InterPro:IPR010982"
                     /db_xref="UniProtKB/TrEMBL:Q53U22"
                     /function="possible regulator"
                     /gene="neoI"
                     /note="ORF SfrA10.10c; also conserved in gene clusters for
                     the aminoglycosides hygromycin B and kanamycin; possibly
                     together with NeoG and NeoH component in a regulatory
                     system"
                     /product="possible regulator, NeoI"
                     /protein_id="CAF33309.1"
                     /transl_table=11
                     /translation="MAGSGSAPEPSERPLLRRFDQRLNELIAALYPDERRRPGYARLAK
                     EIRETTGGAISGTYLWELATGKKRNVTLEQLDVLAEFFGVPPEYFLNEETAARVNSQLK
                     LATALRDSRVRNLALRAEGLSPESLDALLIMVQEARRVQNLASVDDQDHTDRTDHTAAP
                     DGGPAGTSGSTA"
     gene            12947..13969
                     /gene="neoE"
     CDS             12947..13969
                     /codon_start=1
                     /db_xref="GOA:Q53U21"
                     /db_xref="InterPro:IPR002085"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="UniProtKB/Swiss-Prot:Q53U21"
                     /function="biosynthesis of other
                     2-deoxystreptamine-containing aminoglycosides"
                     /function="putative 3-amino-2,3-dideoxy-scyllo-inositol
                     1-dehydrogenase"
                     /gene="neoE"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_zinc_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADSI-DH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 313.3; E-value:
                     2.9e-95)"
                     /gene_kind="biosynthetic"
                     /note="ORF SfrA10.11; putative cyclitol dehydrogenase"
                     /product="putative 3-amino-2,3-dideoxy-scyllo-inositol
                     1-dehydrogenase, NeoE"
                     /protein_id="CAF33310.1"
                     /sec_met_domain="ADSI-DH (E-value: 8.9e-176, bitscore:
                     574.9, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 2.2e-27, bitscore: 86.5,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 3.9e-18, bitscore:
                     57.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVFEAPERAVLTHRDIPAPAPGEALVRVAYNSVCGSDLSFYK
                     GVWHGFTYPVVPGHEWSGSVVDVNGPRGADLVGRNVVGDLTCSCGTCAHCAAGTPTLCE
                     DLGELGFTRDGACAEYMTVPVANLRPLPDTLPLRTACQVEPLAVALNAVDRLGVTPGEK
                     VAVMGAGGIGLLLVQAVRLRGGTVTAVAEPVPERRAAALALGVPAAVGGDPGALVELTR
                     SDPAAVPDVVLEASGYPTAVQEAVEAVRPGGRVGLVGYRIEEAAVMAPHHIVLKVLTVR
                     ASMGPGTRFEEAVDVLASGAVDVDALLSHEFALDDYAKALDVALRRADGNTRSYFNLRA
                     "
     gene            <14048..15322
                     /gene="neoS"
     CDS             <14048..15322
                     /codon_start=1
                     /db_xref="GOA:Q53U20"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="UniProtKB/Swiss-Prot:Q53U20"
                     /function="aminoglycosides with diaminocyclitol units"
                     /function="putative bifunctional L-glutamine:ketocyclitol
                     aminotransferase I and II"
                     /gene="neoS"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     385.6; E-value: 4.2e-117)"
                     /gene_kind="biosynthetic"
                     /note="ORF SfrA10.12"
                     /product="putative bifunctional L-glutamine:ketocyclitol
                     aminotransferase I and II, NeoS"
                     /protein_id="CAF33311.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.6e-106,
                     bitscore: 347.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSPLAVKGGEALRTRPWPAWPQPAPGVPAAVAEVLGSGRWSISG
                     PYRGTDSHERRFARAFADYHGVPYCVPAASGTAGLMLALEACGVGAGDEVIVPGLSWVA
                     SGSTVLGVNAVPVFCDVDPDTLCVSPEAVEALITERTRAVVVVHLYSAVADMDGLTRVA
                     ERHGLPLVEDCAQAHGASYRGVKVGALATAGTFSMQHSKVLTSGEGGAVITRDADLARR
                     VEHLRADGRCLSDGPPAPGAMELVETGELMGSNRCLSEFQAAILTEQLTLLDEQNRTRR
                     ANAARLDGLLGELGLRPQATSEGTTSRTYYTYAARLPEGALEDVPLTDVTGALTAELGF
                     PVQPCYAPIPANRLYAPQTRRRYTLGPDHEARIDPKRFALPVCEDTARRTVTLHHAALL
                     GDAEDMADIAAAFAKVLRHGADLAT"
     misc_feature    14084..14086
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            15493..16785
                     /gene="neoC"
     CDS             15493..16785
                     /codon_start=1
                     /db_xref="GOA:Q53U19"
                     /db_xref="InterPro:IPR002658"
                     /db_xref="UniProtKB/Swiss-Prot:Q53U19"
                     /function="biosynthesis of aminoglycosides with a
                     2-deoxystreptamine moiety"
                     /function="putative 2-deoxy-scyllo-inosose synthase"
                     /gene="neoC"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DHQ_synthase"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DOIS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183:3-dehydroquinate synthase (Score: 381.9; E-value:
                     4.3e-116)"
                     /gene_kind="biosynthetic"
                     /note="ORF SfrF04.2"
                     /product="putative 2-deoxy-scyllo-inosose synthase, NeoC"
                     /protein_id="CAF33312.1"
                     /sec_met_domain="DOIS (E-value: 3.4e-173, bitscore: 566.8,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.1e-70, bitscore:
                     229.1, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTTRIAMEDASFPYRLGTDCAEDVVARLAALEASSYLVVADTTV
                     AELYGAALTAHIDKEAGPSHLLTHEVGEVHKTLATVSALAEQALGRGADRRSVVVALGG
                     GVTGNIAGLMASLLFRGIRLVHVPTTVVAMLDSVLSLKQAVNTTFGKNLAGTFYQPVEV
                     LADTAALRTLPPREIRSGMGEVVKNALAIRPAMLDRLAGALRPDTRYDDETMRWIIAES
                     LAAKADVTSGDKHERRSGLVLEYGHTAGHAIEHASRGAVAHGAGVAVGMTLAAEVSRRL
                     GHADAGLVALHRELVAAAGVEPAVPDHVDTALVKNWLAYDNKRGYLDSPPGHTPMVLLS
                     APGEVLHTGTMPLVPVPLALLEEVVDESAARGGAGGGAAEPAAARTGPVPDGPEAAVPA
                     TPGPVPAGPAAAAPLPSGPAPTAPAAAGPVP"
     gene            16938..18197
                     /gene="neoM"
     CDS             16938..18197
                     /codon_start=1
                     /db_xref="GOA:Q2MFE3"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q2MFE3"
                     /function="aminoglycosides with paromamine as a
                     pseudodisaccaridic precursor unit, such as neomycins,
                     kanamycins,gentamicins, fortimicins"
                     /function="putative UDP-NAc-glucosamine:2-deoxystreptamine
                     4-glycosyltransferase"
                     /gene="neoM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 255.3;
                     E-value: 1.9e-77)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SfrF04.3"
                     /product="putative UDP-NAc-glucosamine:2-deoxystreptamine
                     4-glycosyltransferase, NeoM"
                     /protein_id="CAF33313.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.5e-29,
                     bitscore: 93.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLRLTPFFHHDCVTAWPAEFDAVGGMQVQILRLSRELADRGVEQL
                     VMTVGFPGLPRERVDRPGLRVRVTRAPLPRLRSELTGLVGLNQAWLAAVLTACAPLRRT
                     WRPDLVHVHADGQLWALLAGPLVSRLVGAPYCLTLHCSRLASYEPMSRFDRLQHRLVAA
                     AERYALRRARRVSTLTSRTADTVARLLPLDRALVDVLPDSVGDVRPVARPEAEEYVRSL
                     GVPAGRPVVGWVGRVAHEKGWRDFVAMAERWDAGSGAPGAVFAVVGDGPQRERMREAVE
                     AAGLADRFVFTGFLPHDAVPSVMTALDVLVMPSAHEELGGSALEAMVCGTPVAGYAVGG
                     LRDTVGSVTPSLLVPRGDVAALTRAAGDAVTDAERHRKTVAAAVPDLLGRYGADTVERA
                     LEHYRLAVGRASGGGAGWAP"
     gene            18185..20185
                     /gene="neoT"
     CDS             18185..20185
                     /codon_start=1
                     /db_xref="GOA:Q4A4C2"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="UniProtKB/TrEMBL:Q4A4C2"
                     /function="biosynthesis of the aminoglycosides paromomycin
                     and hygromycin B"
                     /function="putative ABC transporter, ATP-binding protein"
                     /gene="neoT"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 651.3; E-value:
                     2.2e-197)"
                     /gene_kind="transport"
                     /note="ORF SfrF04.4"
                     /product="putative ABC transporter, ATP-binding protein,
                     NeoT"
                     /protein_id="CAF33314.1"
                     /transl_table=11
                     /translation="MGAVTSLRRCAPYLRPHRALMAGACGAAFGSMLAGLAMPLVLQRL
                     VDGPVAERDFSALPWFIGAFALLGVAEAVLLGARRLLVIRPATRLETAMRADVAAHIQR
                     LPLSFHARWQSGQLLSRTVSDITEIGRFVAFSAIYLVVNVAALAVGLVVLAWLAPALAL
                     VVFLAYTPMVVATTVFEQRFRVVARAAQEVGGDLSTTVEESVLGVRVLKVFGRAPETVR
                     RFTGQARRLRVLELRKLSYTAALWWVITALPDLAIVAMIGYGGYGVATGALSLGTLMAA
                     VTVATHLRWPADTLGWLTADASTAAAAADRYWQVRDEPVTVADPARPRPLPSPVRGEIR
                     LEGVHYAYPGGRAAALRGVDLTIRAGSTVAVAGATGSGKSTLLSLLSRLDDPTSGRITL
                     DGVDLRETALADLRSAVCNAFDDPVLFSGTVRDNVTLGVRDAEAPGARDAGARPADGGG
                     AGGSGGAPGADAGAGTGAGRAPGGGVPDGAVWEALRTVRADEFVAALPEGLSTVIGEEG
                     LGLSGGQRQRLALARAILPGPSVLVLDDALSALDVRTEREVEAALRGVLGRVTTVVAAH
                     RPGTLRLADQVVFLSGGRVAATGTHEELMAREPAYRLLVRPPLPVAARETRAPGPGEAP
                     LPGPAEAPAEAQVPAERAVAEDGMAGRGRPG"
     gene            20182..21966
                     /gene="neoU"
     CDS             20182..21966
                     /codon_start=1
                     /db_xref="GOA:Q53U16"
                     /db_xref="HSSP:P63359"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="UniProtKB/TrEMBL:Q53U16"
                     /function="biosynthesis of the aminoglycosides paromomycin
                     and hygromycin B"
                     /function="putative ABC transporter, ATP-binding protein"
                     /gene="neoU"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 356.1; E-value:
                     5.8e-108)"
                     /gene_kind="transport"
                     /note="ORF SfrF04.5"
                     /product="putative ABC transporter, ATP-binding protein,
                     NeoU"
                     /protein_id="CAF33315.1"
                     /transl_table=11
                     /translation="MSGSEDARSRARRDALLRMLLWPKRRRLAAATALALLENVCGLVP
                     PLLIAAAIDRGVPAAVDGRWAPLIGYTAAALATGLATASVKYCFLRYSGRIAQDLLFEL
                     RHRAFAQVMGQPLAFHEAYPSGRVVARLSSDVESVEEMLEMGLDGLFSALFSMVGILAV
                     MLWLDQPMAAVVIALFVPLYALTRWFRHRSRRAYRGTRTAVEGVVQHTVEAYNGVRAVQ
                     AFRREEANARRLDGLDARYAVARADAGLVSAVFSGGVKLIGNLSLVGLLTLGVLRIDQG
                     HLALGTLTAFLLYVHRLYDPIDELASFANAFSAASAGLEKIGALFVRHPAVAEPERPAA
                     LPADPPGGRGAVRFEGVHFGYGQAARPVLSGVDLALEPGRTVALVGTTGAGKSTIAKLV
                     ARLYDPTAGRVTLDGVDLRELADAELRGAVSMITQEAFLFSGSVADNIALGRPDASRAE
                     IRAAAEAVGAHGFVSALPDGYDTDVHKRGTGLSAGQRQLIAMARVMLTSPRVLILDEAT
                     SSMDTSSERAVHEALTRVLAGRTAVIIAHRLSTVAVADRVLVIEDGAVVEDGPPTRLLE
                     GGGRFAGMHRGWLAATTA"
     gene            22175..23800
                     /gene="neoQ"
     CDS             22175..23800
                     /codon_start=1
                     /db_xref="GOA:Q53U15"
                     /db_xref="InterPro:IPR007867"
                     /db_xref="InterPro:IPR013027"
                     /db_xref="UniProtKB/TrEMBL:Q53U15"
                     /function="aminoglycosides with a paromamine-like
                     pseudodisaccaride unit, such as neomycins,kanamycins,
                     gentamicins, fortimicins"
                     /function="putative bifunctional neomycin 6'- and
                     6'''-dehydrogenase"
                     /gene="neoQ"
                     /note="ORF SfrF04.6"
                     /product="putative bifunctional neomycin 6'-and
                     6'''-dehydrogenase, NeoQ"
                     /protein_id="CAF33316.1"
                     /transl_table=11
                     /translation="MKRLRGTLPSDARHAWHPEPLGPAHRDGWDTRDDDRVWDVVVIGS
                     GASGSVAADRLVRQGLDVLMIEEGFRLSPDLGNPELDDMCRTALARDGQGGWTDEGWPW
                     TTSNLGGGTVFYGGASWRYRPFDFDPSELVDAGGLDVRWPYGLAELAPYYDVLERRLGV
                     CGGEEGEGSRGPAHPPTAAAEVLYEAGTALGYEPFPTPLAINRHAHGGRSACERNSLCV
                     SHQCSTGAKGDAVAVFLAPLAAHPNFTLRTGVRALRLNQDRPDAVGSVTCLDRLGRTTH
                     RVRARSFVVACNAIQSAALLLRSRGGRAPDGVGNHSGLVGRGLTMKLSEYVSGVVDAPS
                     AATLADWRAHAGPFSTIAFLDHYLDADCPTGVGGMIYESKNDMPSRIRDDVLELRIETI
                     LADHPNLDNRVRLSSHADEDGVPAVVIDYTPDPRDLRRLAYMTDVCERLLRKAGATGIA
                     HEESGFAQGSCHLHGTCRAGDDPATSVVDGWGRVHSAPNVYVVDGGFMPYPGGLNPTLT
                     IQAHALRSAKAVAGDLVSRHTAHV"
     gene            23974..24873
                     /gene="neoN"
     CDS             23974..24873
                     /codon_start=1
                     /db_xref="GOA:Q53U14"
                     /db_xref="InterPro:IPR000385"
                     /db_xref="InterPro:IPR007197"
                     /db_xref="UniProtKB/TrEMBL:Q53U14"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /function="putative Fe-S oxidoreductase"
                     /function="putative neomyin biosynthet dehydrogenase or
                     epimerase"
                     /gene="neoN"
                     /note="ORF SfrF04.7"
                     /product="putative Fe-S oxidoreductase, NeoN"
                     /protein_id="CAF33317.1"
                     /transl_table=11
                     /translation="MTTDIVWPPPVRQVRAYRNIVVDGACNIRCTYCEVKKTKVDQPAT
                     IRSLDRIFAEYEPDAVLFRVESDGEITLYPKIVDHLQKRAAEGYRVEVLSNGTKLPRAL
                     EGRPDLLWVFSVDGHTEAMNAKRGLKQPQIDRILDAAVELGAELQTVYWGQPVEEVNAY
                     IDLLESRGYRGLLHFMPLLAFKGRPLTVNLRYQDLHPADFLAPPEYFRRWNHIFETGRR
                     DAVCDQITNGYNYQVSGDEIRMVKCDCYSVPKHLVHGFGPIREFDDWPCGTCIANQEFN
                     NSRERMRVPQGRIPLPLV"
     gene            24870..25571
                     /gene="neoP"
     CDS             24870..25571
                     /codon_start=1
                     /db_xref="InterPro:IPR013078"
                     /db_xref="UniProtKB/TrEMBL:Q53U13"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /function="putative phosphatase in neomycin pathway"
                     /gene="neoP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101:phosphoglycerate mutase (Score: 173.9; E-value:
                     4.9e-53)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SfrF04.8"
                     /product="putative phosphatase in neomycin pathway, NeoP"
                     /protein_id="CAF33318.1"
                     /transl_table=11
                     /translation="MTAAQRFVLVRHAEASLNVLRDDDVMPGFDPHAGLTPLGERQARA
                     LAEHLPGDPAVGPPGPAPAPRPGPGSGPRPAVRVYSSPQRRAARTAEVLAAALGVPVLA
                     DGRLAELRAPRAFPRPMTVRQWDAVLEDRLRRPAAEPAGVESWAAQRRRVREFLDSRCP
                     VGADGARWVLVSHSETLQAVLFELLGLEDALLHRTRFKISNTGVFIVDRTEDGCASLVV
                     ANSKTHLARTA"
     gene            25568..25819
                     /gene="neoX"
     CDS             25568..25819
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q53U12"
                     /function="biosynthesis of the neomycin-related
                     aminoglycoside paromomycin"
                     /function="hypothetical protein"
                     /gene="neoX"
                     /note="ORF SfrF04.9"
                     /product="hypothetical protein, NeoX"
                     /protein_id="CAF33319.1"
                     /transl_table=11
                     /translation="MTRMLVVKCLSDETGDDAGDIVARGCVDVDDREFVNILNRLEGYF
                     DCTLWMRSEPARRFAVGDLVERVAAVTAPGGPPEVRRG"
     gene            25812..26912
                     /gene="neoF"
     CDS             25812..26912
                     /codon_start=1
                     /db_xref="GOA:Q53U11"
                     /db_xref="UniProtKB/TrEMBL:Q53U11"
                     /function="biosynthesis of neomycin-related aminoglycoside
                     paromomycin"
                     /function="putative hexosaminyltransferase II or
                     mannosyltransferase"
                     /gene="neoF"
                     /note="ORF SfrF04.10"
                     /product="putative hexosaminyltransferase II or
                     mannosyltransferase, NeoF"
                     /protein_id="CAF33320.1"
                     /transl_table=11
                     /translation="MAEAPAGRALFEIYDEGFDSPSWGGVETALWHLSRSLREAGTEAE
                     FYRSSEGADLDALAARVERDRVDAVFPLVESDLFEGAAWRRLPALHARTVRVWHDVSRL
                     SADLSAPPPCPVHARVPALPGAPVAEGCPARGAHPEGPMREVFLGEWPWTRCFPRRSVI
                     PWAADHVPAKDLCDPSGPVVLQLGKIDTVDAERCLRRLTGAGVALRVVFATWSRRGREA
                     RELVRAHQGAGRRVEVLDAYDIRTDWERVFGGASLFLLPSVFHETYNFAAAEAVQLGVP
                     VAALGEGGNLPRFASLTAPTPDALVDRLLAGGGAVAPRPRPAAGWRDVAARYAEVIREH
                     PAAGAGPAVPAGAGEGRGGREEEHGG"
     gene            26905..27744
                     /gene="neoD"
     CDS             26905..27744
                     /codon_start=1
                     /db_xref="GOA:Q53U10"
                     /db_xref="InterPro:IPR003737"
                     /db_xref="UniProtKB/TrEMBL:Q53U10"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /function="putative 2-N-acetylhexosamine deacetylase"
                     /gene="neoD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SfrF04.11; member of COG2120:
                     MitC/LmbE-family,probable N-acetylhexosamine deacetylases
                     (amidases)"
                     /product="putative 2-N-acetylhexosamine deacetylase, NeoD"
                     /protein_id="CAF33321.1"
                     /sec_met_domain="PIG-L (E-value: 1.5e-21, bitscore: 68.8,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEPTWEAAEDPDRTLRERLRRGRTLLVSPHPDDVAYSCGGLLAA
                     VGRPAHATLLTVFTRSAWALPRRLRRAGARVVSERRREEELRYCRLRGLAEYRPLGFAD
                     AGLRGYDDETELSSPAEADGVRGAVEEAVAEAIRDAGADTVLAPAAVGGHVDHLLVHGA
                     VRGAVGPGGPLTLFYEDLPYAGQRDAVDVERTLREARGLVPFASVDISGVVQQKVRGMY
                     VYGSQTDDECVRETLRHARRGAPRRWTGGTAGAGHAAGRRGAPHTERVWTPAPAGAR"
     gene            complement(27942..29924)
                     /gene="neoL"
     CDS             complement(27942..29924)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFF9"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /function="putative neomycin production protein"
                     /gene="neoL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NeoL"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SfrF04.12c"
                     /product="putative neomycin production protein, NeoL"
                     /protein_id="CAF33322.1"
                     /sec_met_domain="NeoL (E-value: 9.8e-224, bitscore: 733.9,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVTTGVALPALHRAFVETVRRDGGAAALHACACFAEQLLADAAAA
                     HREAAPGPDEDGTGARLAASVVRLRELCTGLAREMAASADAAEPAWSGRAAAAAAPDGA
                     ERRIAVVEDALVLATAVTGALWGSAAARRDQRTAALLRRAADWKTPECYGYDLADPELC
                     YGQAAERLSARSRRAPVLVVGIRTGGSYLAPFWQAAAEDAGVAAGPWHSVRPVRGGAGI
                     TLPGSEIEALPRRLPPGAALVLVDDQPDTGATALAVRDRVARRYPGVRDVVLAAPGRLY
                     DLSGPAVRPLAERPVVRPAARLWQLAGTGGAAALAARARAAGVPLAPGAAHRVEPFRGP
                     FLAEYGPGTAPRGGAAGARGSGAARRLDPRNRPFSLVAGATGAGTSGGTGAPETYHFRF
                     IGTGPHGLHCHQALRALGDLLPPGHVFADGYLVTRHEHGLRPLRAVLPELEEPRRRRVL
                     LAVAESWAALRRVGELGRPGAGAGYEPRARLDGALRRLRERMGRPLPVDGAWTARHVPE
                     RMPLGGADGVLLRTPLPYGHGYWHWQLADTGQGGAGPAGGGAPVLRRFGLDWIWGGGGC
                     LESEIASFVVENRLGAHDRDLLREAVAAACGGTRAFDAGLRLAGEALFWNAKTWLRRCP
                     VVTPPTADRIEAELAAQAAYVAALA"
     gene            30041..31291
                     /gene="neoB"
     CDS             30041..31291
                     /NRPS_PKS="Domain: Aminotran_3 (24-316). E-value: 3.1e-16.
                     Score: 51.1. Matches aSDomain:
                     nrpspksdomains_neoB_Aminotran_3.1"
                     /codon_start=1
                     /db_xref="GOA:Q53U08"
                     /db_xref="InterPro:IPR005814"
                     /db_xref="UniProtKB/TrEMBL:Q53U08"
                     /function="biosynthesis of aminoglycosides with a
                     paromamine-like pseudodisaccharide unit, such as neomycins,
                     kanamycins and gentamicins, and fortimicins"
                     /function="putative bifunctional neomycin 6'- and
                     6'''-aminotransferase"
                     /gene="neoB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 270.6;
                     E-value: 3.7e-82)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SfrF04.13"
                     /product="putative bifunctional neomycin 6'-and
                     6'''-aminotransferase, NeoB"
                     /protein_id="CAF33323.1"
                     /sec_met_domain="Aminotran_3 (E-value: 8.9e-18, bitscore:
                     55.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKNSSLLAEFPTCPRDEKDRPRVFTAASGAWLTDESGFRWIDFD
                     NARGSILLGHGDPVVAEAVARAATGADGTATGWSRRVDAVLERLHALCGGEVVGLFRSG
                     TAAVRAAVLAVREATGRPLLLSAGYHGYDPMWYPSEAPLEPNADGVVDFFFDLGLLREL
                     LRAPERVAAVVVSPDHMHLSPGWYRELRRLCSAAGVVLVADEVKVGLRYAPGLSTAELL
                     APDVWVVAKGMANGHAVSAVGGSRRLLKPLKEVSFTSFFEPTILAAADAALARVATGEP
                     QRAVREAGDRFLRHARKALDDASLPVEIAGDGTFFQFVPATEELEEALYGAANAEGLLF
                     YAGDNQGVSAAFDEAVLGEAERRFARVCERLAPYAGGEPVGDAARYRVAWNVMDGLRQA
                     PRDREETTGLLARLLDD"
     aSDomain        30113..30988
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_neoB_Aminotran_3.1"
                     /evalue="3.10E-16"
                     /label="neoB_Aminotran_3.1"
                     /locus_tag="neoB"
                     /protein_end="316"
                     /protein_start="24"
                     /score="51.1"
                     /tool="antismash"
                     /translation="FTAASGAWLTDESGFRWIDFDNARGSILLGHGDPVVAEAVARAAT
                     GADGTATGWSRRVDAVLERLHALCGGEVVGLFRSGTAAVRAAVLAVREATGRPLLLSAG
                     YHGYDPMWYPSEAPLEPNADGVVDFFFDLGLLRELLRAPERVAAVVVSPDHMHLSPGWY
                     RELRRLCSAAGVVLVADEVKVGLRYAPGLSTAELLAPDVWVVAKGMANGHAVSAVGGSR
                     RLLKPLKEVSFTSFFEPTILAAADAALARVATGEPQRAVREAGDRFLRHARKALDDASL
                     PVEIAGDGTFF"
     gene            31440..35321
                     /gene="neoA"
     CDS             31440..35321
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFF7"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /function="putative neomycin production protein"
                     /gene="neoA"
                     /note="ORF SfrF04.14"
                     /product="putative neomycin production protein, NeoA"
                     /protein_id="CAF33324.1"
                     /transl_table=11
                     /translation="MESPTAAGTEERTGRESAEETARYGAKCARLLRLYRDPEFTGVAL
                     PVHPLDPADARGFAARAHGAVPPGTSGTPGTPGTPEAPEPGEAAEPAETTAPAPRAEPA
                     HEELVAGYAEFLRRRRPDLAARVREVCGEAPWIVRSSGAEDQEDDVNAGGYESLVCPRP
                     GDLYATVAAVVFSGYGEHALAQQRLADPGHRPSPIAAFVQPLVDAAGAADPAAAGETPL
                     LGEEDTARLADLLARAHRAFGMPRVDSEWVLETGAGPVSVTGLTELTPDGRLIGQLSLG
                     FGFASAQRPGDGDNSLAWLTGVPGTTLWRGALLREVSAVRTRLVQVRPAAAFDPEPELG
                     TLTDACRDAWRAACAAAPVDILVPPPRVRASSFLTSVRLEDAWSRYLRLDPGQRERIGH
                     VLVERGGPAEHAAVMFRQEGVAVLRGRPEDVPETASYALADPWRRECHFGTGRPPAVET
                     ETRRTAAVPQGCRLLFASADRAADAVRSGGPLPAPEAMPGAALLDRVPHLPSRVRDRIV
                     RDSYLPDPEVYVRTGSRVASPAFAARAAEALLDGGMPPERVAAVVPEAARAYVRGVASA
                     RTSGAADVRVPGRGSPAWTRPGDVPGGALPAVLAAVRALAAAGGGGTEAALALLGAVAS
                     LASALRALDVYTDAEREEVLARTVAALPLDDAARTEALCRFAARSSAPPTETYRLLALA
                     ARDGDFAERYLAVERCRVDLSAADPGDAARRGRALNDAYRAYAGAGAWQAAGDAVLLDL
                     TRSDLVEAYDSTLKRLLLELVDRPEPGPYRAYLDLLEQWLDLVGAFGLSERERRSVEGF
                     GGWLARWREEPVPDGFALEEELTWSRLLELAAAEARAEGSADGPDTPVEGTDGPDGGGE
                     GPDNPHQLHNALHQWLLARTPRHPAERAPSGVRELQRVSDRFGPGGNKVLRFTRDAVEL
                     DVPLGIHKASLMFRPDRVEGEWTEPPDVTEADAGRLTGLSVLLERCGTWFPELVFRGER
                     VLMAGTWTLRVEARPAAGRERFTLDGMRLALGVFRTLFDGSYDFSYVPAGDVADLPGAF
                     REPGWAEVFRALVGYRLVYDDAELFETLETLPLGTAVGMLCTDAAIRAEVLAASTEGPE
                     GALARLDAAWRRLADREGDPAGWIAGHNAVQQLALLVAARFPGAAVAAFTAADPPGWAD
                     VLGAALLPRADVRDDVVRALAGRPGGDLPLLRRAPWLVVTEASAADAARRVAAAPGAYR
                     RCKQFLVHRYARLLADEGLLAGLVADLEVVPYGAGPSGEEAVAAAVAAAGGRLRRDIRA
                     RPGAGPAPA"
     gene            complement(35483..36346)
                     /gene="aacC8"
     CDS             complement(35483..36346)
                     /codon_start=1
                     /db_xref="GOA:Q53U06"
                     /db_xref="InterPro:IPR003679"
                     /db_xref="UniProtKB/TrEMBL:Q53U06"
                     /function="aminoglycoside 3-acetyltransferase"
                     /function="neomycin resistance"
                     /gene="aacC8"
                     /gene_functions="resistance (resist) AAC3 (Score: 463.4;
                     E-value: 1.5e-141)"
                     /gene_kind="resistance"
                     /note="ORF SfrF04.15c"
                     /product="AacC8"
                     /protein_id="CAF33325.1"
                     /transl_table=11
                     /translation="MDEKELIERAGGPVTRGRLVRDLEALGVGAGDTVMVHTRMSAIGY
                     VVGGPQTVIDALRDAVGADGTLMAYCGWNDAPPYDLAEWPPAWREAARAEWPAYDPLLS
                     EADRGNGRVPEALRHQPGAVRSRHPDASFVAVGPAAHPLMDDHPWDDPHGPDSPLARLA
                     GAGGRVLLLGAPLDTLTLLHHAEALAEAPGKRFVAYEQPVTVGGRRVWRRFRDVDTETE
                     AFPYGRVVPEGVWPFTVIAQDMLAAGIGRTGRVAAAPCHLFEAADVVRFGVEWIESRMG
                     GAAGGA"
     gene            complement(36726..39386)
                     /gene="neoR"
     CDS             complement(36726..39386)
                     /codon_start=1
                     /db_xref="GOA:Q53U05"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011717"
                     /db_xref="InterPro:IPR011990"
                     /db_xref="InterPro:IPR013105"
                     /db_xref="UniProtKB/TrEMBL:Q53U05"
                     /function="putative regulator"
                     /gene="neoR"
                     /gene_functions="regulatory (smcogs) SMCOG1149:LuxR family
                     transcriptional regulator (Score: 592.7; E-value:
                     2.5e-179)"
                     /gene_kind="regulatory"
                     /note="ORF SfrF04.16c"
                     /product="putative regulator, NeoR"
                     /protein_id="CAF33326.1"
                     /transl_table=11
                     /translation="MLPSRAEHRPPAPLLEREPELAAAAHAVEALTGPGATGGLLVFRG
                     EAGIGKTTLLAEIGRRAAGRCTVLSGKGGETVTSVPFHVLRQLLVPALLPLPEARLREL
                     FGDRFDLTAPALGLAAPSAPLADPRGVRDGLDRVVARLAEERRAQPLLVLVDDAHWADT
                     ESLHWLAEFADRLPGLPLLIVLAHRADAAAERPEPAPALLRRLDRQARLTSTLRALTED
                     ATADLARAALGDRTDGPFCREVWAVTGGNPYETVELLATVRDRMLEPVARSAGRLRDLG
                     ASARGSGLVARLEGLGTAATRFAWAAAVLGTDIPLKLAASLAGLPADEAAVCAARLREA
                     RIVTGSDPLEFAHPLVATAVYRSIPPAARTALHGRAAWAVTQEGLGPAAAARHLLEVHP
                     DDDPELVGQLREAAREHLAVGAPDAARRCLERALQEPPPPDAYAEVLYELGCAALLTSP
                     AATVRHLRSALDLPGLAPDLRTDATYRLGQALAHSNELGEASATVAAEAARIPPGRART
                     RLEAAHLMYESFRATEDDPHGRSRRLAARADHLAGDGDAERALLSLRAFDAMLRGEDAA
                     LVLDLCDRALLDGRPAPGVSWTDTEWGFETPAMIGIAYAFTDRPDRARDLFEEAVRAYE
                     ISGWSGAHLAFAHTLLGLAHRRAGDLTRAEAFLREGLRLADRAGRGLAVQWDAVCLLVD
                     TLLARGRPGEARELADAYAFGPPWPSAMVLPDGPCVRGRLLLAEGRTREAADELEAAGR
                     ASEARGRHNGIWAPWACDLARALAPDDPGRAAALAGLAGTHAERFGTATARGEALRCAA
                     LFAAPGEAAGLLAEAVRLLESSPSAYEHALARHDHGVATGSRAELSRAAALAAACGADA
                     LAARAHRALSELPAR"
     gene            39415..39636
                     /gene="neoY"
     CDS             39415..39636
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFH8"
                     /gene="neoY"
                     /note="ORF SfrF04.17"
                     /product="hypothetical protein, NeoY"
                     /protein_id="CAF33327.1"
                     /transl_table=11
                     /translation="MYVRGEPSGGCWVRGMIRAVAGRGAGRRCRAGGAGRFGGVRRGRS
                     AADRVAADRAADRGAGAGGERGGTPDPG"
     CDS             39714..40235
                     /codon_start=1
                     /db_xref="GOA:Q2MFH7"
                     /db_xref="InterPro:IPR005500"
                     /db_xref="UniProtKB/TrEMBL:Q2MFH7"
                     /note="ORF SfrF04.18"
                     /product="hypothetical protein"
                     /protein_id="CAF33328.1"
                     /transl_table=11
                     /translation="MDEARRDRDTEGRARSARPRDGLGRPLPYGAPGVRRQPEGVERTP
                     GGSLREAQRLLDAGLPFHAHEVLEDAWKECAGAGRPEERELCRALAHLAVGLTHAARGN
                     AVGGARLLLRGADRITPYGTGPGPHGTGPGPHGIEVSALAAWARGLAERLDRDGGPVDP
                     AAEAPRLRGR"
     CDS             complement(40437..40859)
                     /codon_start=1
                     /db_xref="InterPro:IPR007438"
                     /db_xref="UniProtKB/TrEMBL:Q2MFH6"
                     /note="ORF SfrF04.19c"
                     /product="hypothetical protein"
                     /protein_id="CAF33329.1"
                     /transl_table=11
                     /translation="MGVAGAHGAGQGRSVNPSAHRVRLRRVYDPPEPADGTRVLVDRLW
                     PRGLAKADAHIDEWPKSATPSTELRRWFHAADGAPDEVFEEFRRRYAAELAEPEAAGAL
                     DRVRDLAREGPLTLLTAARDPERSHAAVLRERLSGG"
     CDS             complement(41084..42448)
                     /codon_start=1
                     /db_xref="GOA:Q53U02"
                     /db_xref="HSSP:P20533"
                     /db_xref="InterPro:IPR001254"
                     /db_xref="InterPro:IPR001316"
                     /db_xref="InterPro:IPR003610"
                     /db_xref="InterPro:IPR004236"
                     /db_xref="InterPro:IPR009003"
                     /db_xref="UniProtKB/TrEMBL:Q53U02"
                     /note="ORF SfrF04.20c"
                     /product="putative serine protease"
                     /protein_id="CAF33330.1"
                     /transl_table=11
                     /translation="MLHRHAGAAFAAAAAVGALVLTALPGAAAAAPAPPATTPSAAVSM
                     GADKTSPEVLAAMQRDLGLSEPQAQRRLVNEAEAGAVAGRLGGVLGADYAGAWVRGAES
                     ATLTVATTDPADALAIRAAGAEARVVRHTLARLDAAKAALDRAAARTDTRDVPVWYVDV
                     RTNSVTVHAAKRGAAEAFLKAAAVNRSLVRVETSAERPRALYDIRGGDAYHMGGGGRCS
                     VGFAVTKGTQHGFATAGHCGRVGTSTSGYNQVAQGTFQGSTFPGRDMAWVAANTNWRST
                     PYVKGAGGQNVQVTGSTQAVVGASVCRSGSTTGWHCGTIQQHNTSVTYPEGTISGVTRT
                     TVCAEPGDSGGSYISGSQAQGVTSGGSGDCRTGGTTYHQPLNPLLQAYALTLTTTTDPG
                     PGPGEPPEGGTWAAGTVYNAGAQVTYGGATYRCLQTHQAQAGWEPPNVPALWQRV"
     CDS             complement(42552..43502)
                     /codon_start=1
                     /db_xref="GOA:Q53U01"
                     /db_xref="InterPro:IPR000847"
                     /db_xref="InterPro:IPR005119"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="UniProtKB/TrEMBL:Q53U01"
                     /gene_functions="regulatory (smcogs) SMCOG1014:LysR family
                     transcriptional regulator (Score: 209.1; E-value: 1.3e-63)"
                     /gene_kind="regulatory"
                     /note="ORF SfrF04.21c"
                     /product="putative lysR-family regulatory protein"
                     /protein_id="CAF33331.1"
                     /transl_table=11
                     /translation="MELELRHLRTVRAIADAGSLTKAATALGLAQPALSTQLKRIERVL
                     GGALFERGRHGVRATPLGELVLERARIVLPAVSDLQRDAVRFARGAAGAEGPRFRLGGT
                     HGPLLGALVDRLAARHPCAAVTTHTSWSEREIAAAVTEGRLDYALIGTCGSSTPPEGDR
                     LAWREIATDPVFVMLPTGHRLASRDRVDLADLAGAAWADVPGDGCFADCFHAACARAGF
                     TPARVYETDTASCVHLVQVGRAVGLCRATFPDTAGLVTRPLAGDPLVWRHLIGWHPDTP
                     AALTAPSVLAQARAAHAEAAARSRSYAAWRASGLP"
     CDS             43828..46047
                     /codon_start=1
                     /db_xref="GOA:Q2MFH3"
                     /db_xref="HSSP:P50216"
                     /db_xref="InterPro:IPR004436"
                     /db_xref="UniProtKB/TrEMBL:Q2MFH3"
                     /note="ORF SfrF04.22"
                     /product="putative isocitrate dehydrogenase"
                     /protein_id="CAF33332.1"
                     /transl_table=11
                     /translation="MTDSTIIYTHTDEAPALATYSFLPVVQAYASAAGVSVETRDISLA
                     GRIIASFPEYLQEGQRIDDALAELGELAKTPGANIIKLPNISASIPQLKAAVAELQEQG
                     YALPDYPDDPKTDEEREIRARYDKVKGSAVNPVLREGNSDRRAPASVKNYAKAHPHRMG
                     AWTADSKTNVATMGADDFRSTEKSAVVAEDGSLRIELAGEDGSTTVLRESVPVLAGEVV
                     DASVMRAEALRAFLSEQVARAKAEGVLFSVHLKATMMKVSDPIIFGHVVRAFFPKTFAA
                     YGDVLAGAGLSPNDGLGGILKGLDSLPQGEEIKASFDAELAEGPALAMVDSDRGITNLH
                     VPSDVIVDASMPAMIRTSGHMWGPDGKEADTLAVLPDSSYSGVYQAVIEDCRAHGALDP
                     ATMGSVPNVGLMAQKAEEYGSHDKTFEIAQPGTVRVVDQAGEVVLEQPVGRGDIFRMCQ
                     TKDAPIRDWVKLAVTRARATGDPAVFWLDEGRAHDARLIEKVKAYLPEHDTEGLRIEIM
                     PPVEATKFSLERIRRGENTISVTGNVLRDYLTDLFPILELGTSAKMLSVVPLMNGGGLF
                     ETGAGGSAPKHVQQLVKENYLRWDSLGEFLALAVSFEHLSQVTGNARAKVLADTLDRAT
                     ATFLNEDKSPTRRVGGIDNRGSHFYLALYWAQELARQTDDAALAEAFGPLAKTLTEQEG
                     AIVEELNAVQGEPADIGGYYQPDPEKAAAVMRPSRTFNQALGTLA"
     CDS             46279..48168
                     /codon_start=1
                     /db_xref="GOA:Q2MFH2"
                     /db_xref="HSSP:P0A6Y8"
                     /db_xref="InterPro:IPR001023"
                     /db_xref="InterPro:IPR012725"
                     /db_xref="InterPro:IPR013126"
                     /db_xref="UniProtKB/TrEMBL:Q2MFH2"
                     /note="ORF SfrF04.23"
                     /product="putative heat shock protein HSP70"
                     /protein_id="CAF33333.1"
                     /transl_table=11
                     /translation="MARAVGIDLGTTNSVVSVLEGGEPAVVTNTEGARTTPSVVGFAKN
                     GDVLVGEVAKRQAVTNVDRTVRSVKRHMGDTGWRFPENGDIDGRRYTAQEISARILQKL
                     KRDAEGYLGEDVRDAVITVPAYFNDAERTATKEAGEIAGLNVLRIVNEPTAAALAYGLD
                     KESDQTILVFDLGGGTFDVSLLEIGDGVVEVKATNGDTHLGGDDWDQRIVEHLAGRFRN
                     AYGIDITKDRMATQRLREAAEKAKIELSAATETSVNLPYLSASAEGPLHLDEKLTRAQF
                     QQMTSDLLERCQVPFRNAVKDAGIEISGIDHVILVGGSTRMPAVADLVKELTGKDPHKG
                     VNPDEVVAIGASLQAGVLKGEVKDVLLLDVTPLSLGIETKGGIMTKLIERNTTIPTKRS
                     EIFTTAEDNQPSVQIQVYQGEREIAAYNKKLGMFELTGLPPAPRGVPQIEVSFDIDANG
                     IMHVTAKDLGTGKEQKMTVTGGSSLPKDDIDRMVREAERHAEEDHRRREAAEARNQGEQ
                     LVYQTEKFLADHADGTGKVPGEIRTEVETAVTELKEKLKGDDTAQIRTAAERVAAVSQK
                     LGQAVYADAQAAQAAGGAQAGPEGGEAGGRDEDEVVDAEIVDEDDRARRGGPA"
     CDS             48165..48506
                     /codon_start=1
                     /db_xref="InterPro:IPR002645"
                     /db_xref="UniProtKB/TrEMBL:Q2MFH1"
                     /note="ORF SfrF04.24"
                     /product="hypothetical protein"
                     /protein_id="CAF33334.1"
                     /transl_table=11
                     /translation="MTAARAGAPDGAPALVVESAGDGRAVLVFAGELDAHRVGALEEAL
                     DDPRLRDATVWELLMRDLTRLDLPCAFALLRAATVRDPPAALHVRGAHRAVRRALREAG
                     ADAVATFEG"
     CDS             48677..49135
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFH0"
                     /note="ORF SfrF04.25"
                     /product="putative integral membrane protein"
                     /protein_id="CAF33335.1"
                     /transl_table=11
                     /translation="MSPLPSSPPVDPGSAGPRRRERARRGPDAAAGCVLVLLELTALAV
                     ILLAWPFLDHFELDPQAPRKPFTLWRYLPAVAVLGGLVLVAAVLAARARAVVTAVSQTA
                     MGVLIAAVLLGGTALQRHEDERGRPVPAPTGGFSGCRSGGDSDECPGG"
     CDS             49233..49997
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFG9"
                     /note="ORF SfrF04.26"
                     /product="hypothetical protein"
                     /protein_id="CAF33336.1"
                     /transl_table=11
                     /translation="MAAVDTGTASTPPADGAPAGAESAARAALAGTGVHLMPPRGALAC
                     LGADAASWAGFAAHWADLTQDAYAARRGTRRLRRYGHFSLATGTGELRLLPPTGFVQPD
                     GTNPLYTSVDRRFDPLTDGFAADPVLLRLIGLLGRVAGALDSPERWSVKVHPFRVVATA
                     DGGGEPTPEGRHRDGVTLVSSLLVGRGNATGGESTVYTPEGGEILSVTLREPASLLLSD
                     DRRTLHGVSPVRPVDPARPAHRDVLVTTFAPG"
     CDS             complement(50079..50465)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFG8"
                     /note="ORF SfrF04.27c; partial ORF"
                     /product="putative proton-dependent transporter"
                     /protein_id="CAF33337.1"
                     /transl_table=11
                     /translation="MLSAAPPGKSGAVSSVQPAFGMSGYALGPAVFVLLLNLFFQRQWL
                     DDAQQRGLSAAEAEEAVDATRSAMARSPGTAGYDPNLLRQSGLDLGWDFTDGLRLTMVV
                     VSLLPLALAVAAWLLIPRRTRSGT"
ORIGIN
        1 gatctgaagt ccgtcgccaa cggcatccgc cagggcgaca cgcgcctgtc cctgctgatg
       61 ggttcgggcg cggcggagga ggcgtacgga ctgcgcttca gccggacgct ggtgaaggtc
      121 ctccgggagg ggctgccgtc ggcgggcggg accctggcgc cggaggccgt ggtggaggcg
      181 gtgcgcggcg acggcggcac ggtggggcag acgatcctgc gggccgagtt cgacggttcg
      241 cggttcgccc ccggccctct gtggctggcc cgcaacgcgc ggcacccggc cgccgccggc
      301 tcgctgctcg gaccggtggg ggcgcaggag ctggcacggg ccgtgcgggc ggtggacgag
      361 tcgctgctcc ccgcctcggt gacgtcggcg ccggacgtcg cgaaggtgcg ggacggcctc
      421 gcggcggccc cgtggtcgcc ggcgcggcag tgggcgctgg acgtggtgga cgcgctggac
      481 accggggcgc ggacggtcgg gctgctcggc tcctggccgg ggacgccgct cacgtcgagc
      541 gtgctgcggc ggacgttcac cgcggcctgc ccggggcccg tggagtcccc gccggcgtcg
      601 tccggcaccg acctgctgcg cgacgccgtc gagtacctgc tgctgcgggc gccgctggcg
      661 ggccggcggc gggtcgcgcc gctggtcgac ttcgtggcgc tgctggcgca cgagacgggc
      721 gtgggcccgc agacgcccga gctgcgcggc tgggcggccg ggataggcgc gctgatcgac
      781 ctgaacgacg cgttcgaccg gctggccgac cggaggcggg acatgcggct gcggctcgtg
      841 gtgagcctgc acgcggcggt cggcgacgaa tggcccgagt cgcttgaggc gtggctgctg
      901 gacgacgggg aggtgcggga ccgcgaggag ttcgcgtgca gcccggaccg ggccggtgtg
      961 gagcggcagc tgggcgcggc gctgcggtgg gcttcgcggc tcgcggcccg gatggacgtg
     1021 ccgctgcgcc gggtggaggt cgcggccccg gcgcccctgc tggtgcagtg gcggcccgag
     1081 gagaccgact tcgggatgcg gctgggtgcc gagcacgatg tcgtgctgcg gtggagcgac
     1141 cgcatccggc cccccgagca cctgtggtgg atcaacgacc acgcgcgcag gacgctgagc
     1201 gccctggagt ccggccccgg gggcacccgg ctggaatggc tcggcgagtc cgacacccgg
     1261 caggtgcgcg agctccgcga gcggctgctc ggcggcccgc gcacgcgcgc ggtggcactg
     1321 gagcaccggc cggcgcacct gcgcgacatg ctggagacgc tgctggcgtc ctcgccgatc
     1381 gtgctgtggc cggacgacga ggcgcaccgc gtcccggacg aggcacgccg ctatctggac
     1441 gcccactggc acctgctgcc gggcgagttc tgccgggcct accgggacgg gtggggcggt
     1501 ccggcggacc ggtccgccgg gaggccggga cgggggcacc tggcccggct gcgcaccgtg
     1561 tgggacgacg cggagtggct ggagttctgc aggtggttcg aacagtacgc gacggatggg
     1621 gagagtcccg catgacctgg cagccgttct actcgggtac cggcggcgcg ccgcgcgagc
     1681 gggtggagct ggccccgccg ccgccgtggc gggtgttccc gcgcccgtcc ctgcacgagc
     1741 ggttcgtgcc gcctcccggt ctggtggagg cggtgaacgc ggcgctgctg ctgcgcagac
     1801 cgctgctgct gaccggtccg gccgggtccg gcaagtcgac ggtgatcgag caggtcgcgg
     1861 cggagctgga gctggggccg gtgctgcgct ggcacatcac gtcccgcagc ggtctgtcgg
     1921 aggccctgta ccggtacgac gccctgggcc ggatccacgc gcagcggctg gagggggcgg
     1981 gaggcggcga cgacatcgcg ccgttcctgc ggatgggccc cctggggacg gcgctgctgc
     2041 cgtcgccccg gccgcgtgcg ctgctcgtcg acgagatcga caagagcgat ctggacctgc
     2101 cgagcgatct gctggacgtg ctggagcggg gcgagttcga gatcccggag ctggcccggt
     2161 acggcaggga cgtggtggcc gtgcgggagt ggggcggcga cgcgcgccac gaggtgacac
     2221 ggggccgggt gcagtgcacc gagttcccgt tcatcgtgat gaccagcaac ggcgagcggg
     2281 acttcccggc ggcgttcctg cgccgctgca tccgcttcac gatgccgatg ccgacgccgg
     2341 agacgctgct gcgggtcgtc gccgcgcatc tgggcgccga cgcggcgggt tcggaggcgg
     2401 ccggggagct ggtgggcgcg ttcgtggagc ggctggccgg cggggagagc ctcgccgtgg
     2461 accagcttct caacgccgtg cacctgctga ccggtgacgg ggcgcccgag ggtgagcggc
     2521 ggcaggccgt cgtcgacctg ctgctgcggg agctgtcccg tgtctgacgc cctgggccgg
     2581 gtgctgtccg cgctccgcgc ggccgttccg ggtgcggacc cggcgggcgg gccgggcgcg
     2641 ggcggcgcgc tggacgggac ggggctggcg gaggccctgt ggctggccgc cgccatggcg
     2701 ggggaccggc cgtccggccc cgcgccggcg gccgggccgg tgccgcccga ggagccgggg
     2761 gacgcggccc cgccgcccgc cgcgggggac acggcgcccc gtggcgggcc ggggacccgg
     2821 acgccggctc cggtggtgcc gggtgcgacc gccgcgcccc gtgccggggc gcgggagctg
     2881 cacgagcggc tggcgggggc gggcacgcgg gtgcgcggcc acgcggtcgc cgcgccgcgc
     2941 gcgacggggt tgccgcgcgc gctggaggtg acgcgggcac tgcggccgtg gaagcgtccg
     3001 tggccggagg gccggcgcgg cacgctggac atcgacgcga ccgtggacgg ctacgcgcgc
     3061 agcggtgagc tgctccccgt gttctcggcg gcccccgagc ggtggttcga cctgacgctg
     3121 gtcgtcgacc gctcccccgg catgcgggtg tgggaggaga ccctggacga cttcaccggc
     3181 gtcctcgacc ggctgggcgc cttccgcacg cttcaggtgc gggacctgct gttcgacgac
     3241 gccggggccc cgcggccgct gggccagctg cggcaggcgg acggccggcg gctggtcgtc
     3301 gtcgtgtccg actgcgcggc cgggccgtgg cggggcgccg ccgtgtggat gctgctgcgg
     3361 gaatgggcgg cgaccacgcc gacggcgctg ctgaacccgc tcccgacgaa gctgtggcgg
     3421 cggggcgggc tggacctccc cacggtccgg ttcaccccgg cggcgcccgg tgcccaccgc
     3481 agccgcgtcc cgcacgaggc gccgcccgcc ctcggtctcg cggcccccgg cggccccggc
     3541 tccccgtccg acggagcgcg cgggggcgcc gccgtcgggc cggccggtac gggagccggg
     3601 gccgggacgg ggccggggtc cggggtgagg gacggggccg gggacggcga cgggtggctg
     3661 cccgttccgg tgctgtcgct gtcgccgcac tcgctggacc ggtggtcgcg ggcggcgatg
     3721 cgcggcgccc ccgaggggtg cacggccgtg ctggtcccgc ccggcggccg gctgtccggc
     3781 cgcccccggc cgcgtacggc ggcgccgtcg tccgccgcgg cggcgcgggg cttcctccgc
     3841 acggcctccc cccgcgcggt gcggctcggg gtgctgtgcg cgccgttcga ccggctgagt
     3901 ctgcggctgc tgcacgtgat ccgccgtgag ctggtgcccg acgcgaccac cgcggacgtg
     3961 gcggaggccg tgacgagcgg cctgttcgag ctggtgccgc ccgccggggc cgacggctcg
     4021 ctggagctgg tgctgtccga ggaggtgagg gcggtgctgc gggaacggct gcccgcgcac
     4081 gaggcgtggc gggtgcacca ggccctcgac cgccatgtcg cgtcccggag cggcggccgg
     4141 ccggggctgc gctcggtcgc gtacgacacc gccggcccgc gggaactggc cgccgagcgg
     4201 gcggcgttcg cccgcgcgtc ccggcagacg ctggagctgc tgggcctcgc ggaaccgggc
     4261 ggcggggctc ccgtcggagc cggccggggc gcgcccggtg acggcggcgc ggaggcgcgg
     4321 gacgtgggcg cccgggactc gggtgcgctg cgcgtgaacg cgtcgagcat ggacgccgcg
     4381 ccacgcgtgg acgcgccggg cgtggacgcg ccggacgcgg cgcgaggcgc gcgggacccg
     4441 gcggcggacg gcgcgagccg tgggccggtg gaggcgggga gcaccgcgtc cgagggcggc
     4501 ggcgaggccg ggtcgccgga cggggcacgg gccgggacgg acggcgtcga gggcggcttc
     4561 ccgccgcctc ccgaggtctt cgccggacgg gcggacatcg tcgattcggt gcgttcccgg
     4621 ctcatccacc cggcgggccg cgtcgtgtgg ctgaccgccg ccggcgcgac ggcggccgtg
     4681 ggccgctcgg cgctggcgct gcacgtggcc caccgcttcc ccggtgagcg gtacttcgcg
     4741 gacctgcgcg gctacggcgc ccatcccgta ccggtcgagg cggcgctgca ccggctgctg
     4801 acggagctgg gggcgccgcc gggcgccgga ccgcacacgg ctcgggagct ggccgccggg
     4861 ctgtgggaag cggtcggcga ccgaagggtc ctgctggtgc tggacgacgt ggccgacccc
     4921 gacgggctga ccgccctgct gccggcggtg ccggggctgt ccgtgctcgc cacgacccgc
     4981 gaaccggacg tggccccccg gtaccggctc gggcatctga cggccgggga ggcggtggac
     5041 gtgatcgccg cgtgggccgg cctcggcggc ggcgaggacc gcgccgccct gcgggagatg
     5101 acggccggtc gcgtgtggtc ggcccgtacg ctgcgggtcc tcggctcctg gatcgcgtcg
     5161 ggctccgcgc cgccgctgcc ccagctggtc cgcatggtcc gcgacctgcc cgcccccgcg
     5221 gacgacgagg ccgacacgct cctgctgcgg gtgcgccacc tgccggccgc cgaacgggag
     5281 gcgctgcgcc tcttcgcgct cgtccccacc ggcgagctga cccgcacgga aggctgggcg
     5341 ctgctcggcg acggcgaggc ggggcgcgag atgcccgccc ggctggaggc ggccggcctg
     5401 ctcgagcccc ggggcgccgg ggtgtaccgg atgccggagg gggtgcgccg cgccgtcacc
     5461 ggcgggggcc cgtccggggc gcggacctcc ggcgccgcca cccggctcgc gcgccaccac
     5521 ctgagcgccg ccgccgcgct gtacgaggag gaccggccgg actccgctct ggcggaccag
     5581 ctgcgggtgc gtgccgccgg gacggccgtc gaccacaccc tgccggtgtg gctcggcaac
     5641 gcgctggcgg tggcggcgac cgccggccgg gacgggacac cgccggccga ggacctcgcc
     5701 gacctgctgc tgctcctcca cccgcgcggc gcgtcgaccc cgtaccgctc ccggttcgag
     5761 caggccgcgc gggcgctgat cgaggcgggc cccaccgggg cggagcggtc ggcggtccgc
     5821 gccgccgccg cgctggccct ggcgcagtac gccgccgggg cgcacggcga ggcggcctcg
     5881 acgctcggcg aggtgcccgc gggctcgtgg gaccgggacg ccgtgctgcg cgggcccgtc
     5941 aaccggctgg ccggtcggct ggcgctggcg cggggggctc tggaggaggc cgagggcctg
     6001 ctggggaggg cgctcgacgc gtaccggacg gacggtgacc gggccggcgt ggcggcggcc
     6061 tccctcgacc tggccgccgc gctcacccgg ctcggccgga ccggcgaggt gttgcgggcg
     6121 gtgctggagg cgttcggcgg ctacccggac tcggtccccc acccgctgat gcgcgggggc
     6181 ctcctggccc tggaggaggc actggccacg gccgggcggt acggggagct gctgtccgcg
     6241 caggaggcgc tgcgcgccca gtacgcgacg gagggcggcg accggcgggc cgaggggctg
     6301 ctcctcaccc ggacggcgcg gacgctgatc aggctgggcc gcctgggcga ggcccgcgag
     6361 gcggcgcgga cggcgctcgg tcacctggca ggcgccgcgg atctggaggg tgaccgggag
     6421 gaggcccggc ggctgctggc cgaggcgggc ggcggggacg cggggacgca cggggcccgc
     6481 accatcgtcg ccctggacac gggcggcgac cacatcgcgg cggggcgggc cctgtcgctc
     6541 gcgctcgcca tgtcgcgggg ggagggtgcc atcggtccgg ccgaccaccg gatggtggtc
     6601 gaggaggccc actgcctggc ggtgctgccg tccggagcgc cggtcgggga gctggtcacg
     6661 gggctggcgc ggtggctgcc cgacgagctg gaggcggccg gggccagccc cgccgcgcgc
     6721 ctcgcggtgc acacggggac cgtcgaggaa cgcggcgggc ggatcgacgc gtccgggctg
     6781 aacgtccggc tcgcggtggc catgacgcgg tcggcggagt tccggtcgct gtccgagaac
     6841 tatccgttcc actcgaccgt gtgcctctcc cccgaggcgt tcgccctgct cggcggggac
     6901 ggcgcgggag gcgggaggcg ggacggcggt ccgggcggcg accgggcccg gcgccgcgac
     6961 gggggcgcgg agcgcgatga ggccgggaga acgggcgggg ccgggccggt cgccgggttc
     7021 agggtgcacg aggtgtccga gggcggccgg gccgtgtgct tcgtcctcac cccgcgcctc
     7081 gacctgtcgg cgtacgacgc cgaactgctg atggcggcgc ggctcttcgc agacgccgac
     7141 ccggacgggc ggctcatggc cgccgcgctg cggaagtcga tcgactcggt gctcgacccc
     7201 gagcgcaccg gccgctacga cccgaacgac ctggacgagc gggagaagtc gctgatcagc
     7261 gctctcctgg agcaggagct gcgcgcgtcg ttccccgggc tgccgggttt ccggctgcgg
     7321 ctgttcctgt cggggcacga ctgggcgttc ccccagatct gggacagcgg catctgtctg
     7381 ctcgtccggg ccgacgagga gcacgcccgc tggtcggtgg ggctgctgcg gacccggccc
     7441 ggcatgacgg tggcgcccgt gaaccgggac gcgccgtcgc cgctgaccac ggaggcccgc
     7501 gaggcggtgc tgtggctgca ccgctccgcg ccgctgcggg agaacctgct gctgcgcctg
     7561 cccgagcggg accgcgtggc gatcctggcc cccgcgtccg gggccgaccg cacggcggag
     7621 ctgttccggc gggtgcggga gcggccggtg cccgaggcgg cgctgcgggc cgtgaccagg
     7681 cgtcgcgaca acgcccgcac ggtacgggag gcggcggccg tgctccggga ggagggcgtg
     7741 ctggtcgtgg gcggcaaccg gcggggcagg gagctggccg gggcgctgcg cctgcccgtg
     7801 ccggacgccg acgcgtacgt gagcgtgcgg ctgacccgcc gccgcccgca ccacgcggcg
     7861 ccgtcgatcg tggcgggggg cgtggcctgg gtcgcggcgg gcccggacga cccgctggag
     7921 ccgctgcccg gcgacctgcc gaacccgcgg cggccgcgct gagtccggtc ccggctccgc
     7981 cccgggcgtc cacggcaccc tctccgtgcg cggcggcgac cgtcaggcgc ccggccaccc
     8041 ggccaaggcc cgtcaagggc cgtcaggcgc tcgccccgca ccggggccgg ccctggaccg
     8101 tgggcggcga cgcgtcgccg aacccgcggg tcaccgtccg ggacacgacg ctcggcgagg
     8161 cggtcaaggc ggcgccgtgg accgacgtgg gcgacgtccc ctggaagggc gcccgcttcg
     8221 ccgagtaccg cgacagcggc ccgggagcgg gcccggcggg tgcgaaccgc ccgcacccgg
     8281 accccgaacg ggccgccggg caggaggccg gcgaccggct gggcggctgg cggcccaccg
     8341 cgtcctgacc ggcccctccc ccgcacgggc ggtggcggcc gtcagcccgc caccgccgcg
     8401 ccggagggcg tcccgcagcg tgacctccgg cgcggtgcgg gacgggaggc ccaccagggg
     8461 gccgctcggc gacgcaccca cgtaggcgac ggcctcgcgg atggggcggc cgggtgaacg
     8521 ggcgcgcacc gcgtgtacgg ccggccgcgg cgcgggtact gctgcacccc ggaaccaggc
     8581 accgcaaccg ggcaccggac cccggacagg agagatgccc atgcgccgcg caggtctcgt
     8641 cgccgtcgcc accgcgctca ccctcggagc cgccggccag agctgggcga ccacgtcgac
     8701 cggcgacgtc gccgccggat ggggtgaccg ggcccgcctc cgggtgacct gggtggaccg
     8761 cacctccttc gagggcggga gcctcgccgt caccgaccgg acctgcgacg gccggtcctt
     8821 ctacgccacg ctcaccctcc acaccggctc cggcgccgtc cgctcgctgg gcgagcggca
     8881 ccacaccggc ggctgcggca cccgcacggt ccacagggac atcgcggcca ccgacgcgag
     8941 cggagtccgc ggcatcacga tggccctgtg ccgcgcaacg gccggagccc ccggccagtg
     9001 cgagacccgg tacctcgccg ccaacccgta ccacggcctc tgacggctcc cggccaggcc
     9061 gcggaaagcg ggggccgggc gccggtctcc agggcggccg ggtccctccg accgcacgga
     9121 ggccgcttcc ggagtggtcc ggaagcggcc tgcggagcgc cctgcggggc ggctctagaa
     9181 gaactcgtca gaagaactcg tcgagaagct ggtagaaggc cagcttctcc ttgtcgacgc
     9241 ggtgggcgcc gtaccgctcc aggaaccgct cggcgtaggc ggggccgaac caggggtcct
     9301 cgtcgatctc cagctcgcgg gcggccaggg cgatgtcggc gtggcggtcg gcgaccccga
     9361 ggcggccgac gtcgatcacg ccggtgaccc ggcaggtccc ggggtcgagc aggacgttgt
     9421 tggggcacag gtcgccatgg cagacgacca ggtcctcctt ctcgggacgg gtgcggtcga
     9481 gctccgccag gagctggtcg ccggtccacc cggcccgctc ctcctgcagg tcgtcgaggt
     9541 ccaccaggcc ctcggcgacg ttccgccggg cctcggcgac cgccgcgtcg aggcgccggt
     9601 cgaaggggca gtcctccacg ggcagctcgt ggagggcgcg ggccagctcc gccatcgcct
     9661 cgaccacggc gaaccgctgg tgctcgggcc actcctcggc cgccgcgacg ccggggacgg
     9721 cctccgtgac gagccacgcg gcggtgtcgt cggcaccgcg ctcgacgacg cgggggacgg
     9781 ggatcccgtg gcggtggagc cactccagcc ggtcggcctc gccggacagg tcgaaggcgg
     9841 agttctcggg ggcgcggggg gcgatcttcg cgtagagctc gggctggggc tcggggccgc
     9901 cggtgagctg gtagacgaag gcgcccgagt ctccttcgtt cactgcgtgc cactcgtggt
     9961 gcgggtactt ccggcgcaac gtgctgtcgt ccatgggcgg catcatggca gaggcggaga
    10021 cgccgttccg cgcctttcgt cggggcccgt aggggtttcg gacattcttg tgcggggtgg
    10081 gggggcgccg gcggacccgg tgcgcccggc gtcgcccgcg ggcccggtgc cggaggtccc
    10141 ggcggggtcg aaggcccgcg cgcagggcga gaggtacgcc tccgtgagcc gcagcaggac
    10201 ggcggtctcg gcggcgaggc cgcacgcctc ccggtcggcg gcgaggacct cggcggccgg
    10261 gtccgggtcc gccccggcga gcctggcggc gcgggcgccg cgcagcacgc aggcggtcac
    10321 atgggcgtcg gcgcgttcgg ccggaatccc ccaccgcgcc acgtgggcgc gggcggcgcg
    10381 ggaaacggcc ggatcggtgt agtggctcag gacgaggagg gcgtcgcgga cctcgatgac
    10441 cttccggtag gcgagctgcc gccaggggag ctggggccgc agcagggtca gggggcggca
    10501 gcgggtgccg gccagggcga cgtgcggcac cgcctccacc aggtcccgcc agagcggcca
    10561 gatccgccag acggtgcggg cgtggccggc ggcgcggcgc agctgcaggg cggtgggcac
    10621 catgagcacg gcggcacaca gcacggcgtg cgcgctcagg acgaggcgga gcaccccgcc
    10681 gggacggcct tcgacggcca tcaggtagta gtgggccagc cagtacagcc cggccgaggc
    10741 cgagccccag cccagcagcg tcaggccgag gttgacgctc cggtgggggc cgctgcggcc
    10801 gtacctccag cagacccggg cgcacagggc gcaggccgcg acgtgcacgg tgacgaggag
    10861 gagccagtag gcggcgcagc gggggcaggc gagcgtgggg tacgggccgt ggcccggcgc
    10921 gtgcggggat ccgaggccgg cgagcgccag gagggcggcc atcacggcgg ccgtggtggc
    10981 gaggaccgcg ccggtgcggc gccggctccc ggtggtgtgc acggcgaagt gcaggatggc
    11041 gccggcgctc acgatgcccg cctggttctt gacgaggccg acggcgcgcg gggagccggt
    11101 gagggcggcg gcgtacgcgc tcacggcctc caggtgcagg gtgagcgcgg cggccgcgca
    11161 ggccacggcg agccacagtc cgcgctggcc cgggtggcgg gcggcggggc gggcccgcag
    11221 cagcacggcg gcccacagca ggagcacgcc ggcggtctgg agtacgcggc ccaggttccc
    11281 cggtaagtca gaggtcatgg tcgccggcca ttccgagggc ctcgtgcagc ttgccgtagg
    11341 ggtccggcgg gaggcaccgg ccgtgcgcgg tgtcgccggt gcggatcagg gtggccagca
    11401 tctcggcctc ctgctcctgg cgggtggagt agtcggtgcg gcccaggacg cggcgtacga
    11461 ggcgcgggct caggtcgccg aagagacggc cgggcagccc ggcggggccc gcgtcgacgg
    11521 tgtggtggtc gaacagcatg tggccgatct cgtggagcac gatgtgctcc tggtgggggc
    11581 gggcggtgcg ctgctcgtag aagatgtggt cgtcggtgtc ggtggcgagc cagaggccgc
    11641 acgtccccgc cgcggcggcc tggatcggca gcgggtgcag gtggaggggg cgtccgcgcc
    11701 gggcggagag ctgggcgcag agcggttcga gggagaaggg gcggggcagg acgagctggt
    11761 ccagcagggg gcggcagcgt cgccgcagcc tggcgatcct gtacgacatg cggttgtacc
    11821 gttcggcctt cctggtacgg cgtgggcggg gcgcggcagg gccggacgcg ccggcgtcct
    11881 ccgccgcacc ggcacgccgg ggcgtgcggc ccccgccgac ctcgcgaacc cgggcacgga
    11941 gccaccgggc cggtgccccg ccgggcgtcc cgcgccgggg gtctccgaag aggccgggag
    12001 gacgggagcg gggagcgagg ggtccgtggg ggcgcccacg gtgcgggagg agatgtgcgc
    12061 gggccccgtg gggccgcctg ccggtcggtg gacggttgaa ggaaagatga cagcctcccc
    12121 atgcgtggcg tcccccgacg acgccagcgg cttcgttatg gacaaccccc gctgttcgag
    12181 cccccgttca cgcccgcagc cccccggcta cgccgtgctc ccggacgttc cggccgggcc
    12241 gccgtccggt gcggccgtgt ggtccgtgcg gtccgtgtgg tcttggtcgt cgaccgatgc
    12301 gaggttctgc accctgcgcg cctcctgcac catgatgagc agggcgtcca ggctctccgg
    12361 ggacagcccc tcggcccgca gggcgaggtt gcgcacgcgc gagtcgcgca gcgcggtcgc
    12421 cagcttgagc tgggagttga cgcgtgcggc cgtctcctcg ttgaggaagt actcgggggg
    12481 caccccgaag aactcggcca gcacgtccag ctgctccagc gtgacgttgc gcttcttgcc
    12541 cgtggccagc tcccagagat aggtgccgga gatggcaccg cccgtggtct cgcggatctc
    12601 cttggccagc cgggcgtacc ccggtcgtct gcgctcgtcc ggatacaggg cggcgatcag
    12661 ctcgttgagc cgctggtcga acctccgcag gagcggacgc tccgacggct cgggggccga
    12721 tccactgccc gccatgcgca cctctcccct ccctgccggt cactccggac gccgtccgcc
    12781 cgcttgagcg gacaactcgc acccgaacat ccaacaacca tcaaccagtg ttgacaagtt
    12841 gactgcatgt gagcgtacga tcatgcgcag cttcatccgc tttagcgaac agaacctgcc
    12901 cggggacccc cgccgggcgc tcccctgacc acggaggttc ggcacgatga aggctctggt
    12961 gttcgaggcc cccgagcggg ccgtcctcac ccaccgcgac atacccgccc cggcgcccgg
    13021 cgaggcgctc gtccgcgtcg cctacaactc cgtctgcggc agcgacctct ccttctacaa
    13081 gggcgtctgg cacggcttca cctaccccgt cgtccccggc cacgagtgga gcggctccgt
    13141 ggtggacgtc aacggcccgc gcggcgccga cctggtcggc cgcaacgtgg tcggcgacct
    13201 gacctgctcc tgcggcacct gcgcgcactg cgcggccggc accccgacgc tctgcgagga
    13261 cctcggggag ctgggcttca cccgcgacgg cgcctgcgcc gagtacatga ccgtccccgt
    13321 cgccaacctg cgtccgctgc ccgacacgct gccgctgcgt accgcctgcc aggtcgagcc
    13381 gctggcggtc gcgctcaacg cggtggaccg gctcggcgtc acccccggcg agaaggtggc
    13441 cgtcatgggc gccggcggca tcgggctgct cctcgtgcag gcggtgcggc tgcggggcgg
    13501 caccgtcacg gcggtggccg agccggtgcc cgagcgccgc gccgccgccc tcgccctggg
    13561 cgtgcccgcc gcggtcggcg gcgatccggg cgcgctggtc gagctgaccc gctccgaccc
    13621 cgcggcggtg ccggacgtcg tcctggaggc gtccggctac cccacggcgg tgcaggaggc
    13681 ggtggaggcc gtccgccccg gcggacgcgt cggcctggtc ggctaccgca tcgaggaggc
    13741 cgcggtgatg gccccgcacc acatcgtgct caaggtgctc accgtccggg cgtccatggg
    13801 ccccggcacc cgcttcgagg aggcggtcga cgtcctggcc tccggcgccg tcgacgtgga
    13861 cgccctgctc agccacgaat tcgcgctcga cgactacgcc aaggccctgg acgtggcgct
    13921 gcgccgcgcc gacggcaaca cccgctccta cttcaacctc cgggcctgag cggcccgcac
    13981 ccggcccgtc cggcacctcc gttccccatc cgcacaccca cggcacgccc tcaggaaagg
    14041 aaggcccatg gtctccccgt tggcagtgaa gggcggcgag gcgttacgca cccgcccctg
    14101 gcccgcctgg ccgcagcccg cccccggagt ccccgccgcg gtggcggagg tgctcggctc
    14161 gggccggtgg tccatcagcg gcccgtaccg cggcacggac tcccacgagc ggcgcttcgc
    14221 gcgggcgttc gccgactacc acggcgtgcc gtactgcgtc cccgccgcga gcggcaccgc
    14281 cggcctgatg ctggccctgg aggcgtgcgg ggtcggcgcc ggcgacgagg tgatcgtccc
    14341 cggcctgtcc tgggtcgcct ccggctccac cgtcctgggc gtcaacgccg tcccggtctt
    14401 ctgcgacgtc gacccggaca cgctgtgcgt ctcccccgag gccgtcgaag cgctgatcac
    14461 cgagcggacc agggccgtcg tggtggtcca cctctactcg gccgtcgcgg acatggacgg
    14521 cctcacccgc gtcgccgagc gccacggcct gcccctcgtc gaggactgcg cccaggccca
    14581 cggggcctcc taccggggcg tcaaggtcgg tgcgctggcc accgccggca ccttcagcat
    14641 gcagcacagc aaggtgctca ccagcggcga gggcggcgcg gtcatcaccc gcgacgcgga
    14701 cctcgcccgc cgggtcgagc acctgcgggc cgacggccgc tgcctgtccg acggcccgcc
    14761 cgcgccgggc gccatggagc tggtcgagac cggcgagctg atgggcagca accgctgcct
    14821 gtccgagttc caggccgcca tcctcaccga gcagctcacc ctgctcgacg agcagaaccg
    14881 cacccgccgc gccaacgccg cccgcctcga cggcctcctc ggcgagctgg gcctgcgccc
    14941 ccaggcgacc tccgagggca ccacctcccg tacgtactac acctacgcgg cgcggctccc
    15001 cgagggcgcg ctggaggacg tcccgctcac cgacgtcacc ggcgccctca ccgccgagct
    15061 cggcttcccc gtccagccct gctacgcccc gatcccggcg aaccggctgt acgccccgca
    15121 gacccgcagg cgctacacgc tcggcccgga ccacgaggcg cgcatcgacc ccaagcgctt
    15181 cgccctcccg gtgtgcgagg acaccgcgcg gcggaccgtc accctgcacc acgccgccct
    15241 gctcggcgac gccgaggaca tggccgacat cgccgcggcc ttcgcgaagg tcctgcggca
    15301 cggcgccgac ctggccactt gaccgccccg gagcaccgcg cccccgcccc ggccccgccc
    15361 tcggcccccg cgcccgcagc cccacccgca gccgcacccg caccgtcatc aggcacggca
    15421 ccgggccccg gccgtgcccc ggccgccacc ccgaccccag cccagcgaac ccccggagga
    15481 ccgggaagca tcatgcagac cacccgcatc gcgatggaag acgcgtcatt cccctaccga
    15541 ctgggcaccg actgcgccga ggacgtcgtc gcgcgcctcg ccgccctcga agccagcagc
    15601 tacctggtgg tggccgacac caccgtcgcc gagctctacg gagccgcgct caccgcccac
    15661 atcgacaagg aggccgggcc gtcccacctc ctcacccacg aggtgggaga ggtccacaag
    15721 accctcgcca ccgtctccgc cctcgccgag caggcgctcg gacggggcgc ggaccgccgc
    15781 tccgtcgtcg tcgccctcgg cggcggggtc accgggaaca tcgccggact gatggcctcg
    15841 ctgctcttcc gcggcatccg cctcgtccac gtgcccacca ccgtggtcgc catgctggac
    15901 tcggtcctct cgctcaagca ggccgtcaac accaccttcg gcaagaacct ggccgggacc
    15961 ttctaccagc ccgtcgaggt cctcgcggac acggcggcgc tgcgcacgct gccgccccgc
    16021 gagatacggt ccggaatggg cgaggtcgtc aagaacgccc tggccatccg gcccgccatg
    16081 ctcgaccggc tggccggcgc gctgcggccc gacacccgct acgacgacga gaccatgcgc
    16141 tggatcatcg ccgagagcct ggccgccaag gccgacgtca ccagcggcga caagcacgag
    16201 cggcgctccg gcctcgtcct ggagtacggg cacaccgcgg gacacgccat cgagcacgcg
    16261 tcccgcggcg cggtcgccca cggcgcggga gtcgccgtgg gcatgaccct cgcagcggag
    16321 gtgtcccgac gcctcggcca cgccgacgcg gggctcgtcg ccctccaccg cgaactggtc
    16381 gccgccgccg gggtggagcc cgcggtgccg gaccacgtcg acaccgcgct cgtcaagaac
    16441 tggctggcgt acgacaacaa gcgcggctac ctcgacagcc cgcccggcca caccccgatg
    16501 gtgctgctct ccgcgccggg cgaggtgctg cacaccggca ccatgccgct cgtacccgtg
    16561 cccctggcgc tgctggagga ggtcgtcgac gagtcggccg cccgcggcgg ggccgggggc
    16621 ggggccgccg agccggcggc ggcgcgcacg ggccccgtac cggacggacc ggaggcggcg
    16681 gtaccggcga cgccggggcc cgtgccggcc ggacccgcgg cggcggcccc cctgccgagc
    16741 ggacccgccc cgaccgcgcc cgcggcggcc ggacccgtgc cgtaaccgcc ccgccccgcg
    16801 ccaccggccc cgcgccggcc gcacggcccc tcggcccgcc cccgcgcgcc ggccgcacgg
    16861 ccccgcgccg ggccgtgccg gcaaccgccc cgcaccccgc ccatcgccgt cctctccccg
    16921 tggagtcccc cgtgcgtgtg ctgcggctca cccccttctt ccaccacgac tgcgtcaccg
    16981 cctggcccgc ggagttcgac gccgtcgggg gcatgcaggt gcagatcctc cgcctctcgc
    17041 gggaactggc cgaccgcggc gtggagcagc tcgtcatgac cgtcgggttc cccggcctgc
    17101 ccagggagcg cgtcgaccgg cccggcctcc gggtccgggt cacccgggcg ccgctgcccc
    17161 ggctgcgctc cgaactgacc ggcctcgtgg ggctcaacca ggcgtggctc gccgcggtgc
    17221 tgacggcctg tgcgccgctg cgccgcacct ggaggcccga cctggtgcac gtccacgcgg
    17281 acggccagct ctgggcgctg ctcgccgggc cgctcgtctc gcgtctggtc ggcgcgccgt
    17341 actgcctcac cctgcactgc tcgcggctgg cctcgtacga gccgatgtcc cgcttcgacc
    17401 ggctccagca ccggctggtg gcggcggccg agcggtacgc gctgcggcgg gcgcgccggg
    17461 tgtcgacgct gacctcgcgc accgcggaca cggtggcgcg gctgctgccg ctcgaccggg
    17521 ccctggtgga cgtgctgccc gactcggtcg gcgacgtgcg gccggtggcg cggccggagg
    17581 ccgaggagta cgtgcggtcg ctcggcgtgc ccgccgggcg gccggtggtg ggctgggtcg
    17641 gccgggtcgc gcacgagaag gggtggcggg acttcgtcgc gatggcggag cggtgggacg
    17701 ccgggtcggg cgccccgggg gcggtgttcg ccgtggtggg cgacgggccg cagcgggagc
    17761 ggatgcggga ggcggtcgag gcggcggggc tcgcggaccg gttcgtgttc accggtttcc
    17821 tgccccatga cgccgtgccg tccgtgatga cggcgctgga cgtcctcgtc atgccgtccg
    17881 cccacgagga gctgggcggc agcgcgctgg aggccatggt gtgcggcacg cccgtcgcgg
    17941 gctacgcggt cggcgggctg cgcgacacgg tcggctcggt cacgccctcc ctgctcgtcc
    18001 cgcggggcga cgtggcggcg ctgacccgcg ccgccggcga cgcggtcacg gacgccgaac
    18061 ggcaccgcaa gacggtcgcg gcggccgttc ccgacctgct gggccggtac ggcgcggaca
    18121 ccgtcgagcg ggcgctggag cactaccggc tggccgtcgg ccgggcgtcc ggagggggtg
    18181 ccgggtgggc gccgtgacgt cgctgcggcg ctgtgcgccg tatctgcgcc cgcaccgggc
    18241 gctgatggcg ggggcgtgcg gggcggcctt cgggtcgatg ctcgcgggcc tggccatgcc
    18301 gctggtgctc cagcggctgg tcgacgggcc ggtcgcggag cgggacttct ccgccctgcc
    18361 gtggttcatc ggcgccttcg ccctgctcgg cgtcgccgag gccgtgctgc tgggggcccg
    18421 gcggctgctc gtcatccgtc cggcgacccg cctggagacg gcgatgcggg cggacgtggc
    18481 cgcgcacatc cagcgcctcc cgctgtcgtt ccacgcccgc tggcagtccg gccagctgct
    18541 gtccaggacg gtgtccgaca tcacggagat cggccggttc gtcgcgttct ccgccatcta
    18601 tctggtggtg aacgtggcgg cgctcgccgt cggcctggtc gtcctggcgt ggctggcgcc
    18661 ggcgctcgcg ctggtcgtgt tcctcgcgta cacgccgatg gtggtcgcga ccaccgtctt
    18721 cgagcagcgg ttccgggtgg tggcgcgggc ggcgcaggag gtggggggcg acctgtccac
    18781 cacggtggag gagtcggtgc tcggcgtacg ggtgctgaag gtgttcgggc gggcgccgga
    18841 gacggtgcgc cgcttcaccg ggcaggcgcg ccggctgcgc gtcctggagc tgcgcaagct
    18901 ctcgtacacg gcggccctgt ggtgggtcat cacggcgctg ccggacctgg cgatcgtggc
    18961 gatgatcggg tacggcgggt acggcgtcgc caccggggcg ctgtcgctgg gcacgctgat
    19021 ggcggcggtg acggtggcca cccatctgcg ctggccggcg gacacgctgg gctggctgac
    19081 ggcggacgcc tcgacggccg ccgccgcggc cgaccggtac tggcaggtgc gggacgagcc
    19141 ggtgacggtg gcggacccgg cccggccgcg ccccctgccg tcgccggtgc gcggcgagat
    19201 ccgcctggag ggcgtgcact acgcctaccc cggtggccgc gcggcggcgc tgcggggcgt
    19261 cgacctgacg atccgggcgg gcagcacggt ggccgtggcc ggggcgaccg ggtccggcaa
    19321 gagcacgctg ctgtcgctgc tgtcgcggct ggacgacccg acgtccgggc ggatcaccct
    19381 ggacggggtg gacctgcgcg agacggccct ggccgacctg cggtcggcgg tgtgcaacgc
    19441 gttcgacgat ccggtgctct tctcgggcac ggtccgggac aacgtgacgc tgggcgtgcg
    19501 ggacgcggag gcgcccggcg cgcgggacgc gggggcccgg ccggcggacg gcggcggggc
    19561 cgggggctcc ggcggggcgc cgggggcgga cgccggggcc gggacggggg ccgggcgggc
    19621 gccgggcggc ggggtgcccg acggcgccgt ctgggaggcg ctgcggacgg tgcgggcgga
    19681 cgagttcgtc gcggcgctgc ccgaggggct gtccaccgtg atcggcgagg agggcctcgg
    19741 gctctcgggc ggccagcggc agcggctggc gctggcgcgg gccatcctgc ccggaccgtc
    19801 ggtgctggtg ctggacgacg cgctgtcggc gctggacgta cggaccgaac gggaggtgga
    19861 ggccgccctg cgcggggtgc tcggccgggt caccacggtc gtggccgcgc accggcccgg
    19921 cacgctgcgc ctggccgacc aggtggtgtt cctctccggc ggccgggtcg ccgccacggg
    19981 cacgcacgag gagctgatgg cgcgcgagcc ggcgtaccgg ctgctggtcc ggcccccgct
    20041 cccggtcgcg gcgcgggaga cgcgggcgcc cggccccggg gaggcgccgt tgcccggccc
    20101 ggcggaggcg ccggcggagg cgcaggtgcc cgcggagagg gcggtggcgg aggacggcat
    20161 ggcgggaagg gggcggccgg gatgagcggc tcggaggacg cgcggtcccg cgcccggcgg
    20221 gacgccctgc tgcggatgct gctgtggccg aagcggcggc ggctggcggc ggccacggcg
    20281 ctggcgctgc tggagaacgt gtgcgggctg gtgccgccgc tgctgatcgc cgcggccatc
    20341 gaccgcgggg tgcccgcggc ggtggacggg cggtgggcgc cgctgatcgg ctacaccgcc
    20401 gcggcgctgg ccaccgggct ggccacggcg agcgtcaagt actgcttcct gcgctactcc
    20461 gggcggatcg cgcaggacct gctgttcgag ctgcggcacc gggcgttcgc ccaggtgatg
    20521 gggcagccgc tggccttcca cgaggcgtac ccctcgggcc gggtcgtggc ccggctgtcg
    20581 agcgacgtgg agtcggtcga ggagatgctg gagatgggcc tggacggcct gttctccgcg
    20641 ctgttctcga tggtcggcat cctcgccgtg atgctctggc tcgaccagcc gatggcggcg
    20701 gtggtgatcg cgctgttcgt cccgctgtac gcgctgacgc ggtggttccg gcaccggtcg
    20761 cgccgggcct accggggcac ccggacggcc gtcgagggcg tcgtgcagca caccgtcgag
    20821 gcgtacaacg gcgtccgggc cgtgcaggcc ttccgccgcg aggaggcgaa cgcgcggcgg
    20881 ctggacgggc tggacgcccg gtacgcggtg gcgcgggccg acgccgggct ggtgagcgcc
    20941 gtgttcagcg gcggtgtgaa gctcatcggc aacctgtcgc tggtggggct gctgacgctg
    21001 ggggtgctcc gcatcgacca ggggcacctg gcgctgggca cgctcacggc gttcctgctg
    21061 tacgtgcacc ggctgtacga cccgatcgac gagctggcga gcttcgccaa cgcgttctcg
    21121 gcggcctcgg ccgggctgga gaagatcggc gcgctgttcg tgcgccatcc ggcggtggcc
    21181 gagccggagc gcccggcggc gctgccggcc gacccgccgg gcggccgggg cgccgtgcgg
    21241 ttcgagggcg tccacttcgg ctacggccag gcggcccggc cggtcctctc gggcgtcgac
    21301 ctggcgctcg aaccgggccg cacggtcgcc ctcgtgggta cgaccggcgc cgggaagtcc
    21361 accatcgcca agctggtggc ccggctctac gaccccacgg cggggcgggt cacgctggac
    21421 ggggtcgacc tgcgggagct ggccgacgcg gagctgcgcg gcgccgtctc gatgatcacg
    21481 caggaggcgt tcctgttctc cgggtcggtg gccgacaaca tcgccctggg ccggccggac
    21541 gcgtcgcggg cggagatccg ggccgccgcg gaggcggtgg gcgcgcacgg gttcgtcagc
    21601 gcgctgccgg acggctacga caccgacgtg cacaagcgcg gcacgggcct gtcggccggc
    21661 cagcggcagc tgatcgccat ggcacgggtg atgctgacct cgccccgcgt gctgatcctc
    21721 gacgaggcga cgtccagcat ggacacctcc tcggagcggg ccgtgcacga ggcgctgacc
    21781 cgggtcctgg ccgggcgcac cgcggtgatc atcgcgcacc gcctgtccac ggtggccgtc
    21841 gccgaccgcg tcctggtgat cgaggacggg gcggtggtgg aggacgggcc cccgacgcgg
    21901 ctgctggagg gcggtgggcg cttcgccggc atgcaccggg gctggctggc cgccacgacg
    21961 gcgtgacgcg ggccgccgcg cgccgggcgg gacacgcccg cgccccgcac gccgcgaggc
    22021 gcgccgggcc cgcgctccgg accgggcgca cgccgggggc ccgcgctccg tcgccccgca
    22081 cgggcactcc ccctacgacc cctacgacac ctacgacacc tacgacccca acgaccacga
    22141 cgaccacgac gaccacgacg acgaaaggca caggatgaag cgccttcgag gcaccctgcc
    22201 ctcggacgca cggcacgcgt ggcacccgga gccgctgggt cccgcgcacc gcgacggctg
    22261 ggacacccgt gacgacgacc gggtctggga cgtcgtcgtg atcggcagcg gcgccagcgg
    22321 ctccgtcgcc gcggaccggc tcgtccggca gggcctggac gtcctgatga tcgaggaggg
    22381 cttccggctc tcccccgacc tcggcaaccc cgagctggac gacatgtgcc gcacggcgct
    22441 ggcccgtgac ggccagggcg gctggaccga cgagggctgg ccgtggacga cgtccaacct
    22501 cggcggcggc acggtcttct acggcggcgc ctcctggcgc taccggccgt tcgacttcga
    22561 cccgagcgag ctggtggacg ccggcgggct cgacgtccgc tggccgtacg ggctggccga
    22621 actcgcgccg tactacgacg tgctggaacg ccggctgggg gtgtgcggcg gcgaggaggg
    22681 cgagggcagc cgcggccccg cgcacccccc gacggccgcg gccgaggtgc tctacgaggc
    22741 gggcaccgca ctcggctacg agcccttccc caccccgctg gccatcaacc ggcacgccca
    22801 cggcgggcgt tcggcgtgcg agcgcaactc gctgtgcgtg agccaccagt gctcgacggg
    22861 cgccaagggc gacgcggtcg cggtcttcct cgcaccgctc gccgcgcacc ccaacttcac
    22921 cctgcgcacc ggtgtacggg ccctgcgcct gaaccaggac cggccggacg ccgtcggttc
    22981 ggtgacctgc ctggaccggc tcggccgcac cacgcaccgc gtccgcgccc ggtcgttcgt
    23041 cgtcgcgtgc aacgcgatcc agagcgccgc gctgctgctg cgctcccgcg gcgggcgcgc
    23101 cccggacggc gtggggaacc actccggcct ggtcgggcgc ggcctgacga tgaagctgag
    23161 cgagtacgtg agcggtgtgg tcgacgcgcc gtccgccgcg acgctcgccg actggcgcgc
    23221 gcacgcgggc ccgttctcca cgatcgcgtt cctcgaccac tacctggacg ccgactgccc
    23281 caccggggtc ggcgggatga tctacgagtc gaagaacgac atgccctcgc gcatccgcga
    23341 cgacgtgctg gaactgcgca tcgagacgat cctggccgac cacccgaacc tcgacaaccg
    23401 ggtgcggctc tcctcgcacg ccgacgagga cggcgtgccg gccgtggtca tcgactacac
    23461 gcccgacccc cgcgacctgc gccgcctcgc gtacatgacg gacgtgtgcg agcggctgct
    23521 gcggaaggcg ggcgcgaccg ggatcgcgca cgaggagagc ggcttcgccc aggggagctg
    23581 ccacctgcac ggcacgtgcc gggccggcga cgacccggcg acgtcggtgg tcgacggctg
    23641 gggccgggtc cactcggcgc ccaacgtgta cgtcgtcgac ggcggcttca tgccgtaccc
    23701 gggcggcctg aaccccacgc tcaccatcca ggcgcacgcg ctgcgcagcg ccaaggcggt
    23761 cgccggcgac ctcgtgtccc ggcacaccgc gcacgtctga gccccgccgc gccgcacggc
    23821 cgcggcggcc cgcaccacgc accacccccg caccaccccc gcaccacgtc ccacacccac
    23881 acgccacgca ccacacacac gcacacgcac cacgcccagc acgcgacgcg acgcgacgcg
    23941 accgacccag cgtcccgaac gaggagacac gccatgacca ccgacatcgt gtggccgccc
    24001 ccggtgcggc aggtccgcgc ctaccgcaac atcgtcgtgg acggcgcctg caacatccgg
    24061 tgcacctact gcgaggtcaa gaagaccaag gtggaccagc ccgccaccat ccgttccctg
    24121 gaccggatct tcgccgagta cgagccggac gcggtgctgt tccgggtgga gtccgacggc
    24181 gagatcaccc tctacccgaa gatcgtcgac catctgcaga agcgggccgc cgaggggtac
    24241 cgcgtcgagg tgctgagcaa cggcaccaag ctgcccaggg ccctggaggg gcgccccgac
    24301 ctgctgtggg tgttctcggt cgacgggcac accgaggcca tgaacgccaa gcgcggcctg
    24361 aagcagccgc agatcgaccg catcctcgac gccgccgtcg agctgggggc ggagctccag
    24421 accgtgtact ggggccagcc ggtggaggag gtcaacgcct acatcgacct gctggagtcc
    24481 cgcggctacc ggggactgct ccacttcatg ccgctgctgg ccttcaaggg ccggccgctg
    24541 accgtgaacc tgcgctacca ggacctgcac ccggcggact tcctggcgcc gccggagtac
    24601 ttccgccgct ggaaccacat cttcgagacc ggcaggcggg acgcggtctg cgaccagatc
    24661 accaacggct acaactacca ggtgtccggc gacgagatcc ggatggtcaa gtgcgactgc
    24721 tactcggtgc ccaagcacct ggtgcacggc ttcggcccga tccgggagtt cgacgactgg
    24781 ccgtgcggga cctgcatcgc caaccaggag ttcaacaact cgcgcgagcg gatgcgcgtc
    24841 ccgcaggggc ggatcccgct gccgctcgta tgacggccgc ccagcggttc gtgctggtcc
    24901 ggcacgccga ggcgagcctg aacgtgctgc gcgacgacga cgtcatgccg ggcttcgacc
    24961 cgcatgccgg gctgacgccg ctcggcgagc ggcaggcgcg ggcgctcgcc gagcacctgc
    25021 ccggcgaccc ggcggtaggc ccgccgggtc ccgccccggc cccgcggccc ggtccgggct
    25081 cggggccccg ccctgccgtg cgggtgtact ccagcccgca gcggcgggcc gcccgcaccg
    25141 ccgaggtgct ggccgccgcg ctgggcgtgc ccgtcctggc ggacggccgg ctggcggagc
    25201 tccgggcgcc gcgcgccttc ccccggccca tgacggtccg ccagtgggac gccgtgctgg
    25261 aggaccggct gcggcgcccg gcggccgagc cggcgggggt ggagagctgg gcggcgcagc
    25321 ggcggcgcgt ccgggagttc ctggactccc gctgcccggt cggcgccgac ggggcgcggt
    25381 gggtgctcgt gtcgcactcc gagacgctgc aggccgtcct cttcgagctg ctggggctgg
    25441 aggacgcgct gctgcaccgc acccgtttca agatcagcaa caccggtgtg ttcatcgtgg
    25501 acaggacgga ggacggatgc gcttccctgg tggtggcgaa cagcaagacg cacctggcca
    25561 ggacggcatg acccgcatgc tcgtcgtgaa gtgcctgagc gacgagaccg gcgacgacgc
    25621 cggggacatc gtcgcccggg ggtgcgtgga cgtggacgac cgcgagttcg tcaacatcct
    25681 caaccggctg gagggctact tcgactgcac gctgtggatg cggtcggagc cggcccggcg
    25741 cttcgccgtc ggcgacctgg tggagcgggt cgccgcggtg acggcccccg gcggcccgcc
    25801 ggaggtgcgc cgtggctgag gcgcctgccg ggcgggccct gttcgagatc tacgacgagg
    25861 gcttcgactc gccgtcgtgg ggcggtgtgg agaccgccct gtggcacctg tcgcgctccc
    25921 tgcgcgaggc gggcaccgag gcggagttct accggtcctc ggagggcgcc gacctggacg
    25981 cgctggccgc gcgtgtggag cgggaccggg tggacgcggt cttcccgctg gtggagagcg
    26041 acctgttcga gggcgcggca tggcggcggc tgcccgcgct gcacgcccgg acggtccgcg
    26101 tctggcatga cgtcagccgg ctctcggccg acctgtcggc gccgccgccc tgccccgtgc
    26161 acgcgcgggt acccgcgctg ccgggggctc cggtcgcgga gggctgcccg gcgcggggcg
    26221 cgcaccccga ggggccgatg cgcgaggtgt tcctgggcga gtggccctgg acgcgctgct
    26281 tcccgcgccg gtcggtgatc ccctgggccg ccgaccacgt gccggcgaag gacctgtgcg
    26341 acccgtccgg gccggtggtg ctccagctcg gcaagatcga cacggtggac gcggagcgct
    26401 gcctgcgccg gctcaccggg gccggggtgg ccctgcgggt cgtcttcgcc acgtggtcgc
    26461 gccggggccg ggaggcccgc gagctggtgc gcgcgcacca gggggcgggg cggcgcgtcg
    26521 aggtgctgga cgcctacgac atccgtacgg actgggagcg ggtcttcggc ggcgcgtcgc
    26581 tgttcctgct gccgtccgtg ttccacgaga cctacaactt cgccgcggcg gaggccgtcc
    26641 agctcggtgt gccggtggcg gccctcggcg agggcggcaa cctgccgcgc ttcgcgtcgc
    26701 tgaccgcgcc gacgcccgac gccctggtgg accggctgct ggcggggggc ggggcggtgg
    26761 cgccgcgtcc ccgcccggcg gcgggctggc gggacgtcgc cgcccggtac gcggaggtca
    26821 tccgggagca cccggccgcc ggtgccggtc cggcggtccc cgcgggcgcc ggcgaggggc
    26881 ggggcggacg ggaggaggag cacggtgggt gagccgacgt gggaggcggc ggaggacccc
    26941 gaccggacgc tgcgggagcg gctgcggcgg ggccggacgc tgctggtctc accgcacccg
    27001 gacgacgtgg cgtactcctg cggcgggctg ctggccgcgg tcggccgccc cgcgcacgcg
    27061 acgctcctga cggtgttcac ccggtccgcg tgggcgctgc ccagacggct gcggcgggcc
    27121 ggggcgcggg tggtcagcga gcggcgcagg gaggaggagc tgcggtactg ccggctgcgg
    27181 ggcctcgcgg agtaccggcc gctcggcttc gccgacgcgg ggctgcgcgg ctacgacgac
    27241 gagaccgagc tgtcgtcccc ggccgaggcg gacggcgtgc gcggcgcggt ggaggaggcc
    27301 gtcgccgagg cgatacgcga cgcgggcgcc gacacggtgc tggccccggc cgccgtcggc
    27361 gggcacgtcg accacctcct ggtgcacggc gcggtgcgcg gcgcggtggg ccccggcggc
    27421 ccgctgaccc tgttctacga ggacctgccg tacgcggggc agcgcgacgc ggtggacgtc
    27481 gagcggacgc tgcgggaggc gcgcggcctg gtgccgttcg cgagcgtcga catctccggt
    27541 gtcgtgcagc agaaggtgcg cggcatgtac gtgtacggca gccagacgga cgacgagtgc
    27601 gtgcgcgaga cgctgcggca cgcccggcgc ggcgcgccgc gccggtggac gggcgggacg
    27661 gcgggggcag ggcatgcggc gggccgccgg ggcgcgccgc acaccgagcg ggtgtggacg
    27721 cccgccccgg cgggtgcccg gtgacccggc ctcgtggagg cacggcgccg gtgacccggc
    27781 ctcgtggagg cacggcgatc cggccgggcg gggacccggc gggccgggac ccggcgggcg
    27841 gccgacccgg cggggccccg gtggacgtgc ccggccaggc cccggcggcc cgcctcggcg
    27901 gggccccgcc gggtcgccgg gccggccgcc ggcggggtgt gtcaggccag tgcggcgacg
    27961 tacgcggcct gggcggccag ctccgcctcg atccggtcgg cggtgggcgg cgtgacgacc
    28021 gggcagcgcc gcagccacgt cttggcgttc cagaacagcg cctcgcccgc cagccgcagc
    28081 ccggcgtcga aggcgcgcgt accgccgcag gccgcggcga cggcctcccg cagcaggtcc
    28141 cggtcatggg cgccgagccg gttctcgacg acgaaggagg cgatctcgct ctccaggcag
    28201 ccgccgccgc cccagatcca gtccagcccg aaccgccgca gaaccggggc gccgccgccc
    28261 gcgggacccg cgcccccctg gccggtgtcc gcgagctgcc agtgccagta cccgtgcccg
    28321 tatggaagcg gggtgcgcag cagcaccccg tcggcgcccc cgaggggcat ccgctccggc
    28381 acgtgccggg ccgtccaggc gccgtcgacg ggcaggggcc ggcccatgcg ctcgcgcagt
    28441 cgccgcagcg ccccgtcgag ccgggcccgc ggctcgtacc cggcgcccgc gcccggacgg
    28501 cccagctcgc cgacgcggcg cagcgcggcc caggactcgg cgaccgcgag cagtacgcgg
    28561 cgccgccgcg gctcctccag ctccggcagt accgcgcgca gcgggcgcag cccgtgctcg
    28621 tggcgggtca ccaggtagcc gtcggcgaag acgtggccgg gcgggagcag gtcccccagg
    28681 gcgcgcaggg cctggtggca gtggaggccg tgcggtccgg tgccgatgaa gcggaagtgg
    28741 tacgtctccg gggcgcccgt accgccgctc gtgcccgcgc ccgtcgcacc ggcgaccagg
    28801 gagaagggcc ggttgcgggg atcgaggcgg cgggccgcgc cgctcccgcg cgcgccggcg
    28861 gcgcccccgc gcggggcggt gcccggcccg tactccgcga ggaaggggcc ccggaacggc
    28921 tccacgcggt gggcggcgcc cggtgcgagg ggcacgcccg ccgcccgtgc gcgggccgcg
    28981 agcgcggcgg cgccgcccgt gccggcgagc tgccacaggc gggccgccgg gcggacgacc
    29041 ggccgctcgg ccagcgggcg gacggccggg ccgctcaggt cgtagagccg acccggcgcg
    29101 gccaggacga cgtcccgcac gcccggatag cgccgggcga cccggtcgcg cacggcgagg
    29161 gcggtggcac cggtgtccgg ctggtcgtcc accaggacca gcgccgcacc gggcggcagg
    29221 cggcgcggca gggcctcgat ctcggagccc ggcagggtga tgccggcgcc gccgcgtacg
    29281 gggcggacgc tgtgccaggg ccccgccgcg accccggcgt cctcggcggc ggcctgccag
    29341 aacggcgcca ggtacgagcc gcccgtccgt atgcccacga cgagcacggg cgcccgccgg
    29401 gaccgggcgg agaggcgttc ggcggcctgg ccgtagcaga gctcgggatc ggccaggtcg
    29461 tagccgtagc actccggggt cttccagtcg gcggcgcggc gcagcagggc ggcggtgcgc
    29521 tggtcccgcc gggccgcggc cgatccccac agcgcgcccg tcacggcggt ggcgagcacg
    29581 agcgcgtcct ccacgacggc gatccgccgc tcggcgccgt cgggagcggc ggcagcggcg
    29641 gcccggccgc tccacgcggg ctcggcggca tcggcggaag cggccatctc gcgggcgagt
    29701 ccggtgcaca gctccctcag ccggaccacg gatgcggcga gtcgggcgcc ggtcccgtcc
    29761 tcgtccggtc cgggcgcggc ctcccggtgc gccgcggcgg cgtcggcgag caactgctcc
    29821 gcgaagcagg cgcaggcgtg cagggcggcc gcgccgccgt cccgccggac ggtctccacg
    29881 aaagcacggt gcagggctgg cagtgccacg ccggtcgtca ccacgtccgc tcctcctggt
    29941 gggaagtcac cggtcccggt gctcgtcgcc cggatcccgc ccccactgtg cgcccgatcc
    30001 gaattcccgt tcaatgcccg actttcccct ggggtgaaca atgacgaaaa actcttccct
    30061 gctggccgaa ttccccacct gcccgcgcga cgagaaagac cgcccgcggg ttttcaccgc
    30121 cgcgtccggc gcctggctga cggacgagtc cggtttccgc tggatcgatt tcgacaatgc
    30181 gcgggggtcg attctgctcg ggcacggcga cccggtggtc gccgaggccg tcgcgcgggc
    30241 ggcgaccggc gcggacggca ccgcgaccgg gtggagccgg cgggtcgacg cggtgctgga
    30301 gcggctgcac gccctgtgcg gcggcgaggt cgtggggctc ttccggtcgg gtacggccgc
    30361 ggtccgggcc gccgtgctgg ccgtgcggga ggcgacgggg cggccgctgc tgctgagcgc
    30421 cggctaccac ggctacgacc cgatgtggta cccgtccgag gcgccgctgg agcccaacgc
    30481 ggacggggtg gtggacttct tcttcgacct cggcctgctg cgggagctgc ttcgggcccc
    30541 cgagcgggtc gccgccgtcg tcgtgtcgcc cgaccacatg cacctgtcgc ccggctggta
    30601 ccgcgagctg cgccggctgt gctcggcggc cggggtggtg ctggtcgcgg acgaggtgaa
    30661 ggtgggactg cgctacgcac cgggcctgtc cacggccgag ctgctcgcgc ccgacgtgtg
    30721 ggtggtcgcc aagggcatgg ccaacgggca cgcggtctcc gcggtcggcg ggtcccgccg
    30781 gctgctgaag ccgctgaagg aggtgtcgtt cacctcgttc ttcgagccca cgatcctggc
    30841 cgcggcggac gccgcgctcg cccgggtcgc caccggggag ccgcagcggg cggtccggga
    30901 ggccggggac cgcttcctgc gccacgcccg caaggcgctg gacgacgcgt ccctgccggt
    30961 cgagatcgcc ggcgacggca cgttcttcca gttcgtaccg gcgaccgagg agctggagga
    31021 ggcgctctac ggggcggcga acgccgaggg cctgctcttc tacgcgggcg acaaccaggg
    31081 cgtgtcggcc gccttcgacg aggccgtgct cggcgaggcc gagcggcggt tcgcccgcgt
    31141 gtgcgaacgg ctggcgccgt acgcgggcgg ggagccggtc ggcgacgcgg cccgctaccg
    31201 ggtcgcctgg aacgtgatgg acggactgcg ccaggccccg cgcgaccgcg aggagaccac
    31261 cggcctgctg gcgcggctgc tggacgactg agcccgcccc ggacccgggg gcgcaccgcc
    31321 tccgggtccg gccctccccc gcgcacccca cgcgggaatt caccaggaat ccggggatga
    31381 ccaggaatga ccaggaattc aggatcccag aaggaaccga gagattgagg cgcctttcca
    31441 tggagagtcc aaccgctgcc ggcaccgaag aaaggaccgg ccgggaatcg gcggaggaga
    31501 ccgcgaggta cggtgcgaaa tgcgcccggc tcctgcgcct gtaccgcgac ccggaattca
    31561 ccggggtggc gctgccggtg caccccctcg acccggccga cgcccgcggg ttcgccgcgc
    31621 gggcgcacgg cgcggtcccg ccgggaacct cgggaacacc ggggacgccg gggacgccgg
    31681 aagcgccgga gccgggggag gccgccgagc cggcggagac gaccgcaccg gccccccggg
    31741 cggagccggc ccacgaggaa ctggtcgcgg ggtacgcgga gttcctgcgc cgcaggcggc
    31801 ccgacctcgc cgcccgggtg cgcgaggtgt gcggcgaggc accctggatc gtccgcagtt
    31861 cgggcgcgga ggaccaggag gacgacgtca acgcgggcgg ctacgagagc ctggtgtgcc
    31921 cgcgccccgg cgacctgtac gcgacggtcg cggcggtggt cttcagcggg tacggcgagc
    31981 acgccctcgc ccagcagcgg ctggccgacc cgggccaccg cccctccccc atcgccgcgt
    32041 tcgtccagcc cctcgtcgac gcggccggcg cggcggaccc ggccgccgcg ggcgagaccc
    32101 cgctgctcgg cgaggaggac acggcccggc tcgccgatct gctggcgcgg gcgcaccgcg
    32161 ccttcggcat gccccgcgtg gactccgagt gggtcctgga gaccggggcg gggcccgtct
    32221 ccgtcaccgg gctcaccgaa ctcaccccgg acgggcggct gatcgggcag ctctcgctgg
    32281 gcttcggctt cgcgtccgcc cagcgcccgg gcgacggcga caacagcctg gcgtggctga
    32341 ccggcgtccc cggcacgacg ctgtggcgcg gggccctgct gcgcgaggtg tccgccgtgc
    32401 ggacgcggct ggtgcaggtc cgcccggccg ccgcgttcga cccggagccg gagctgggca
    32461 ccctcaccga cgcctgccgc gacgcctggc gcgccgcgtg cgccgccgcc ccggtcgaca
    32521 tcctcgtgcc gccgccgcgg gtgcgcgcct cgtcgttcct cacctccgtg cggctggagg
    32581 acgcgtggag ccgctatctg cgcctcgacc ccgggcagcg ggagcggatc ggtcacgtgc
    32641 tcgtggagcg gggcggcccg gccgagcacg cggcggtgat gttccgccag gagggcgtcg
    32701 ccgtgctgcg gggccgcccc gaggacgtcc cggagacggc gtcgtacgcg ctggcggacc
    32761 cctggcggcg ggagtgccac ttcggcaccg gccggccgcc cgcggtggag accgagaccc
    32821 ggcgcacggc cgccgtgccg cagggctgcc ggctgctgtt cgcgtccgcg gaccgggccg
    32881 cggacgcggt ccggtccggc gggccgctgc ccgcaccgga ggcgatgccg ggcgccgccc
    32941 tcctggaccg ggtgccccac ctgccgtcgc gggtcaggga ccggatcgtg cgggacagct
    33001 acctgccgga ccccgaggtg tacgtccgga ccgggtcgcg cgtggcgtcg cccgcgttcg
    33061 cggcccgcgc cgcggaggcg ctgctcgacg gcggcatgcc gccggagcgg gtcgcggccg
    33121 tggtgcccga ggccgcgcgg gcgtacgtgc ggggggtggc ctcggcccgc acgtcgggcg
    33181 ccgccgacgt gcgggtaccc ggtcgcgggt cgcccgcctg gacgcggccg ggggacgtgc
    33241 cgggcggggc cctcccggcc gtgctcgcgg ccgtccgcgc cctcgcggcg gccgggggcg
    33301 gcggcaccga ggccgcgctg gccctgctgg gcgcggtggc gtcgctggcg tcggcgctgc
    33361 gggcgctgga cgtgtacacg gacgcggagc gcgaggaggt cctcgcccgg accgtggccg
    33421 ctctcccgct ggacgacgcg gcgcgcacgg aggcgctgtg ccggttcgcc gcccgctcgt
    33481 cggcgccgcc cacggagacg taccggctgc tcgccctcgc cgcgcgcgac ggcgacttcg
    33541 ccgagcggta cctggccgtg gagcgctgcc gggtcgacct gtcggccgcc gatccgggcg
    33601 acgcggcgcg gcgcggccgt gccctgaacg acgcgtaccg cgcctacgcg ggggccgggg
    33661 cgtggcaggc ggccggggac gcggtgctgc tcgacctgac gaggagcgat ctcgtcgagg
    33721 cgtacgacag caccctgaag cggctgctgc tggagctggt ggaccgcccg gagccgggcc
    33781 cgtaccgcgc ctacctcgac ctgctggagc agtggctgga cctggtgggc gcgttcggcc
    33841 tgtcggagcg tgagcggcgc tcggtcgagg ggttcggcgg gtggctcgcg cggtggcggg
    33901 aggagcccgt gccggacggc ttcgccctgg aggaggagct gacctggagc cggctgctgg
    33961 agctggcggc cgcggaagcg cgggcggagg gctccgcgga cggcccggac acgccggtgg
    34021 agggcacgga cggcccggac ggcggcgggg agggcccgga caacccgcac cagctccaca
    34081 acgcgctcca ccagtggctg ctcgcccgca ccccccgcca ccccgccgag cgggccccct
    34141 cgggggtgcg ggagctccag cgcgtgtcgg accggttcgg gccgggcggc aacaaggtgc
    34201 tgcgcttcac gcgggacgcg gtggagctgg acgtaccgct gggcatccac aaggcgagcc
    34261 tgatgttccg ccccgaccgg gtcgagggcg agtggacgga gccgccggac gtcacggagg
    34321 cggacgccgg acggctcacc ggactgtcgg tcctgctgga gcgctgcggc acgtggttcc
    34381 ccgaactggt cttccgcggc gagcgggtgc tgatggcggg gacgtggacg ctccgggtgg
    34441 aggcccgccc ggcggccggg cgcgagcggt tcacgctcga cgggatgcgg ctggcgctcg
    34501 gggtgttccg cacgctcttc gacggctcgt acgacttctc gtacgtcccg gccggggatg
    34561 tcgccgacct gccgggggcg ttccgggagc cggggtgggc cgaggtgttc cgggccctcg
    34621 tcggctaccg cctcgtctac gacgacgccg agctgttcga gacgctggag acgctgccgc
    34681 tgggcaccgc cgtcggcatg ctctgcacgg acgccgccat ccgggccgag gtgctggccg
    34741 cctccaccga gggtccggag ggcgcgctgg cgcggctcga cgcggcgtgg cggcggctgg
    34801 ccgaccggga gggcgacccg gccgggtgga tcgccgggca caacgcggtg cagcagctcg
    34861 cgctgctggt ggcggcccgc ttccccggcg cggcggtggc cgcgttcacg gcggcggacc
    34921 cgccgggctg ggcggacgtg ctgggtgcgg cgctgctgcc ccgcgcggac gtgcgcgacg
    34981 acgtggtgcg ggcgctcgcc ggacggcccg gcggcgacct gccgctgctt cggcgggccc
    35041 cgtggctggt cgtgacggag gcgagcgcgg cggacgccgc ccgtcgggtg gccgcggcgc
    35101 cgggggcgta ccggcgctgc aagcagttcc tcgtgcaccg gtacgcgcgg ctgctggcgg
    35161 acgagggact gctggccggg ctcgtggcgg acctggaggt cgtgccgtac ggggccgggc
    35221 cgtccggcga ggaggcggtg gcggcggcgg tggccgcggc gggcgggcgg ctgcgccgcg
    35281 acatccgcgc gaggcccggc gcgggcccgg cgcccgcctg acggcagcgg gcgcggcgga
    35341 cgcggggccg gaccggtacg cggccggacc ggcgcccggc cgccggagcc gcgcgggacc
    35401 cggccgatga gggacccggc cggccccgcc ccggcccgcc cggccggggc gggcggggcc
    35461 gcgcccggcc ggggccggtg gctcacgcgc cgccggccgc gccccccatc cggctctcga
    35521 tccactcgac gccgaagcgg accacgtcgg cggcctcgaa gaggtggcag ggggcggcgg
    35581 cgacccggcc ggtccggccg atcccggcgg cgagcatgtc ctgggcgatg acggtgaacg
    35641 gccagacccc ctcgggcacc acccgcccgt aggggaacgc ctcggtctcg gtgtcgacgt
    35701 cgcggaagcg ccgccagacc cgtcgcccgc cgacggtcac gggctgctcg tacgcgacga
    35761 accgcttgcc gggggcctcg gccagtgcct ccgcgtggtg cagcagcgtc agggtgtcca
    35821 gcggggcgcc gagcagcagt acccgtccgc cggccccggc gagccgggcg agcgggctgt
    35881 ccggtccgtg cgggtcgtcc caggggtggt cgtccatgag cgggtgggcg gccggcccga
    35941 ccgcgacgaa gctcgcgtcg gggtgccggc tgcggaccgc gccgggctgg tggcgcaggg
    36001 cctcggggac ccggccgttg ccccggtcgg cctcgctgag cagcgggtcg taggcgggcc
    36061 actcggcgcg tgcggcctcc cgccacgcgg ggggccactc ggcgaggtcg tagggcgggg
    36121 cgtcgttcca gccgcagtag gccatgaggg tgccgtcggc gccgacggcg tcgcggagcg
    36181 cgtcgatcac ggtctgcggg ccgcccacga cgtagccgat cgccgacatg cgggtgtgca
    36241 ccatgacggt gtcgccggcg ccgacgccga gtgcctcgag gtcgcgcacg agccggccgc
    36301 gggtgacggg gccgccggcg cgctcgatca gttccttctc gtccacggac cgaacctagc
    36361 ggcgcgtgca cggggcccgc cgggaccggg gcggcttttc ggccggccgg ccgccggggc
    36421 ggcttttcgg cgctccgcgt ccgcccacac cgcccgcacc ggccgcacgg ggtcccaccg
    36481 gcgtccccgg aaggcccggc ccggcgaaac cggcggcccc ggcgacccac accaccgcca
    36541 gaacggccga aaggctgctc cggatcactc cggaacagcc ttcgacctgc gactttcaca
    36601 agtcgggacg acaggatttg aacctgcgac cccttgaccc ccagtcaagt gcgctaccaa
    36661 gctgcgccac gtcccgatgc gcgtcgtccc ggtctcgccg ggtgagcgcg caagagaaca
    36721 ttacctcacc gggcgggcag ctccgaaagc gcccggtggg cgcgggcggc cagggcgtcg
    36781 gcgccgcagg cggcggcgag ggcggcggcc cgcgagagct cggcgcggga gccggtggcg
    36841 acgccgtggt cgtgccgggc gagggcgtgc tcgtacgcgg acggggacga ctccagcagc
    36901 cgcaccgcct cggccaggag cccggccgcc tcgccgggcg cggcgaacag ggcggcgcag
    36961 cgcagcgcct ccccgcgggc ggtggcggtg ccgaagcgct ccgcgtgggt gccagccagg
    37021 cccgcgaggg cggcggcccg gccgggatcg tccggggcga gggcccgggc gaggtcgcag
    37081 gcccagggcg cccagatccc gttgtgccgg ccgcgcgcct cggacgcccg ccccgccgcc
    37141 tccagctcgt cggcggcctc gcgggtcctg ccctcggcga ggagcagccg gccccgcacg
    37201 cagggcccgt cggggagcac catggcgctg ggccagggcg gcccgaaggc gtacgcgtcg
    37261 gccagttcgc gggcctcgcc gggcctgccg cgcgccagga gggtgtccac caggaggcag
    37321 acggcgtccc actggacggc gaggccgcgg cccgcgcggt cggcgaggcg caggccctcg
    37381 cggaggaacg cctcggcacg ggtcaggtcg ccggcccggc ggtgggcgag gccgagcagg
    37441 gtgtgcgcga aggcgaggtg ggcgccgctc cagccggata tctcgtacgc gcggaccgct
    37501 tcctcgaaga ggtcgcgcgc ccggtcgggc cggtcggtga aggcgtacgc gatgccgatc
    37561 atggcggggg tctcgaaccc ccactcggtg tcggtccagc tcacgccggg ggcggggcgg
    37621 ccgtcgagga gggcgcggtc gcacaggtcg agcacgaggg ccgcgtcctc gccgcgcagc
    37681 atcgcgtcga aggcgcgcag cgacagcagg gcgcgttcgg cgtcgccgtc gcctgccagg
    37741 tggtcggcgc gggcggcgag gcggcgggag cggccgtgcg ggtcgtcctc ggtggcgcgg
    37801 aacgactcgt acatgaggtg ggcggcctcg aggcgggtgc gggcgcggcc gggcgggatg
    37861 cgggcggcct cggcggcgac ggtggcggag gcctccccga gttcgttgct gtgggcgagg
    37921 gcctggccga ggcggtacgt ggcgtcggtg cgcaggtccg gggcgaggcc gggcaggtcg
    37981 agggcggagc gcaggtggcg gacggtcgcg gccggggagg tgaggagggc ggcgcagccc
    38041 agttcgtaca ggacctcggc gtaggcgtcg ggcggcggcg gttcctggag ggcgcgttcg
    38101 aggcagcggc gggccgcgtc gggggcgccg acggcgaggt gctcgcgggc ggcctcccgg
    38161 agctgcccga ccagctcggg gtcgtcgtcg gggtggacct ccagcaggtg gcgggcggcg
    38221 gcggccgggc cgaggccctc ctgggtgacg gcccaggcgg cgcggccgtg cagggcggtg
    38281 cgggcggcgg gcgggatgga gcggtagacg gcggtggcga ccagcgggtg ggcgaactcc
    38341 agcgggtcgg agccggtgac gatgcgggcc tcgcggaggc gggcggcgca gaccgcggcc
    38401 tcgtcggcgg gcaggccggc gagggacgcg gccagcttca gcgggatgtc ggtgcccagg
    38461 accgccgccg cccaggcgaa ccgggtggcg gccgtgccga gcccctccag acgggcgacg
    38521 aggccgctgc cgcgcgcgga ggcgcccagg tcgcgcagcc gccccgcgga gcgggcgacg
    38581 ggctccagca tgcggtcccg gacggtcgcc aggagttcga ccgtctcgta cgggttgccg
    38641 ccggtgaccg cccagacctc gcggcagaac gggccgtcgg tgcggtcgcc gagcgcggcg
    38701 cgggccaggt cggcggtggc gtcctcggtg agcgcgcgca gggtgctggt gagcctggcc
    38761 tgccggtcga ggcggcgcag cagggcgggg gcgggttcgg ggcgctcggc ggcggcgtcg
    38821 gcgcggtggg cgaggacgat gagcagcggc aggccgggca ggcggtcggc gaactcggcg
    38881 agccagtgca gcgactcggt gtccgcccag tgcgcgtcgt cgacgaggac gaggaggggc
    38941 tgcgcgcgcc gctcctcggc gaggcgggcg acgacccggt cgaggccgtc gcgcacgccc
    39001 cgggggtcgg cgagcggggc gctgggcgcg gcgaggccga gggcgggcgc cgtgaggtcg
    39061 aagcggtcgc cgaacagctc ccgcagccgg gcctcgggga gggggaggag cgccggtacg
    39121 aggagctggc gcaggacgtg gaacggcacg gaggtgacgg tctcaccgcc cttgccggac
    39181 aggacggtgc agcggcccgc ggcgcggcgg ccgatctcgg cgagcagggt cgtcttgccg
    39241 atgccggcct cgccccggaa gaccagcagg ccgccggtgg cgccggggcc ggtgagcgcc
    39301 tcgacggcgt gggccgcggc ggccagctcc ggctcccgct ccagcagcgg tgcgggcggc
    39361 cggtgttcgg ccctggacgg cagcatcctc ttctcccttt cccctgttgc tcgcatgtac
    39421 gttcgaggag agcctagtgg ggggtgctgg gtgcggggga tgattcgggc cgtcgcgggg
    39481 cggggtgcgg ggcggcggtg ccgcgcgggc ggtgcgggcc gcttcggcgg ggtccggcgc
    39541 gggcggtcgg cggcggaccg ggtggcggcg gaccgggcgg cggaccgggg ggcgggggcc
    39601 ggcggggagc ggggcgggac tccggacccg ggctgacggg gcttggcacc gggccggacg
    39661 gggcccgccc ggtgcgcggc gcacgccggt ggcgcgggcg ggacaatggg cggatggacg
    39721 aggctcgcag ggaccgggac acggaggggc gcgcccgcag cgcacggccc cgcgacgggc
    39781 tggggcggcc gctgccgtac ggggcgccgg gcgtccgacg gcagccggag ggcgtggagc
    39841 gcacgcccgg cgggtccctg cgggaggcgc agcggctgct ggacgcgggg ctgccgttcc
    39901 acgcccacga ggtgctggag gacgcctgga aggagtgcgc cggggcgggg cgccccgagg
    39961 agcgcgagct gtgccgggcc ctggcccacc tcgcggtggg cctgacgcac gcggcgcgcg
    40021 gcaacgccgt gggcggcgcg cggctgctcc tgcgcggcgc ggaccggatc accccgtacg
    40081 ggacggggcc gggaccgcac gggacggggc cggggccgca cgggatcgag gtgtccgccc
    40141 tcgcggcctg ggcgcgcggc ctggcggagc ggctggaccg ggacggcggc ccggtggacc
    40201 cggcggcgga ggcaccccgc ctgaggggac gctgaccgcg ccgggcgggg cgcacgggcc
    40261 cgcagggcgc acgacacccg cgagagcgcg gcggggcgca ccggcccggc gggcgggccc
    40321 ggcagggcgt acgacgcccg cgcggggcgt acccgccccc gggccgtgcg gtctgcgggg
    40381 gggcgacgcg gcgatgtggc cggaaacgga acggtgccgc tccgagggcg ccgccctcag
    40441 ccgccgctca gccgctcgcg cagcacggcg gcgtggctgc gctccgggtc cctggcggcc
    40501 gtcaggagcg tgagcggccc ctcgcgggcg aggtcccgga cgcggtcgag ggccccggcc
    40561 gcctccggct cggcgagctc ggccgcgtac cgccggcgga actcctcgaa cacctcgtcc
    40621 ggcgccccgt ccgccgcgtg gaaccagcgg cgcagctccg tcgagggcgt ggcggacttg
    40681 ggccactcgt cgatgtgcgc gtccgccttg gccaggccgc gcggccacag ccggtccacg
    40741 agcacgcgcg tcccgtcggc gggttcgggc gggtcgtaca cccgccggag ccggacgcgg
    40801 tgcgcggagg ggttcacgct tcgaccctgc cccgccccgt gcgcccccgc aacgcccacc
    40861 ggccgaccgg gtgggtcggg gaacggcgcg cccccggctc cggggcagtc cggcggccgg
    40921 ggggcgtccc gcggaggcgg aggcgggggc gcggacggcg gggacgcggg cggagggcgt
    40981 ccccgaggag gcgggggcgt acgggcccgg cggaccggga cccgtacgcg ccctcagacg
    41041 tgacgtttct gctgggcagg ctccacggcg cggacggttc ctcctacacg cgctgccaga
    41101 gcgccggcac gttcggcggc tcccagcccg cctgcgcctg gtgggtctgg aggcaccggt
    41161 aggtggctcc gccgtaggtg acctgggcgc ccgcgttgta gacggtgccc gccgcccacg
    41221 tgccgccctc cgggggctcg cccggccccg gcccggggtc ggtcgtggtg gtgagggtca
    41281 gggcgtacgc ctggaggagc gggttgagcg gctggtggta cgtcgtaccg cccgtccggc
    41341 agtcgccgga gccgcccgag gtgacgccct gcgcctggct gccggagatg tacgagccgc
    41401 ccgagtcgcc cggctcggcg cacacggtcg tgcgggtgac gccgctgatc gtgccctccg
    41461 ggtaggtgac gctcgtgttg tgctgctgga tcgtgccgca gtgccagccg gtggtggacc
    41521 ccgagcggca gaccgacgcg ccgacgacgg cctgcgtgga accggtgacc tggacgttct
    41581 gcccgcccgc gcccttcacg tacggggtgg agcgccagtt ggtgttggcc gccacccagg
    41641 ccatgtcgcg gccggggaag gtggagccct ggaaggtgcc ctgcgcgacc tggttgtagc
    41701 cgctggtgga ggtgccgacg cggccgcagt ggccggccgt ggcgaagccg tgctgggtgc
    41761 ccttggtgac ggcgaagccg accgagcagc gcccgccgcc gcccatgtgg tacgcgtcgc
    41821 cgccccggat gtcgtacagg gcgcggggcc gctcggcgga cgtctcgacc cggacgaggg
    41881 accggttgac ggcggcggcc ttcaggaacg cctcggccgc gccccgcttg gcggcgtgga
    41941 cggtgacgga gttggtgcgg acgtcgacgt accagacggg cacgtcgcgg gtgtcggtgc
    42001 gggcggcggc ccggtcgagg gcggccttgg cggcgtcgag gcgggccagc gtgtggcgga
    42061 ccacgcgggc ctcggcaccg gcggcgcgga tcgcgagcgc gtcggcgggg tcggtggtgg
    42121 cgaccgtcag ggtcgcggac tcggcacccc gcacccaggc gccggcgtag tcggcgccga
    42181 ggacgccgcc gaggcgcccg gcgaccgctc cggcctcggc ctcgttcacc aggcgccgct
    42241 gggcctgcgg ctcgctgagc cccaggtccc gctgcatggc ggccaggacc tcgggggacg
    42301 tcttgtcggc gcccatgctc accgcggccg agggggtggt ggcgggcggg gccggcgcgg
    42361 cggccgccgc gccggggagc gcggtgagca cgagggcgcc gaccgctgcc gcggcggcga
    42421 acgcggctcc ggcgtgtctg tggagcatcc ggtgttctcc tcggtttcgg atggggtcga
    42481 gtggggggtt ccgaaaccgt aggtgttgcc gaaagaccct cagaagatgt cgcttttccc
    42541 tctcttcggc gttatgggag cccggaagcc ctccaggcgg cgtaactgcg gctgcgggcc
    42601 gccgcctcgg cgtgcgcggc gcgcgcctgg gcgaggacgg agggggcggt gagcgcggcg
    42661 ggcgtgtccg ggtgccagcc gatcaggtgc cgccacacga gggggtcccc ggcgagcggg
    42721 cgggtgacga gcccggccgt gtcggggaac gtggcgcggc acagcccgac ggcgcggccg
    42781 acctggacga ggtggacgca ggacgccgtg tcggtctcgt agacgcgcgc cggggtgaag
    42841 cccgcgcggg cgcaggcggc gtggaagcag tcggcgaagc agccgtcgcc ggggacgtcc
    42901 gcccaggcgg cgccggccag gtcggcgagg tccacgcggt cgcgggaggc gagccggtgg
    42961 ccggtcggga gcatcacaaa aacggggtcg gtggcgatct cccgccaggc gagccggtcg
    43021 ccctcgggcg gggtgctgct gccgcaggtg ccgatgaggg cgtagtcgag gcggccctcg
    43081 gtgacggcgg cggcgatctc ccgctcggac caggaggtgt gggtggtgac ggcggcgcac
    43141 gggtggcggg cggcgagccg gtcgacgagg gcgccgagca gcgggccgtg ggtgccgccg
    43201 aggcggaagc gggggccctc ggcgccggcg gcgccccgcg cgaaccgcac ggcgtcgcgc
    43261 tggaggtcgc tgacggcggg cagcacgatc cgggcccgct ccaggacgag ctcgcccagc
    43321 ggtgtggccc gcacgccgtg ccgcccccgc tcgaacaggg ccccgcccag gacccgctcg
    43381 atccgtttga gctgggtgct cagcgcgggc tgggccaggc cgagcgcggt ggcggccttg
    43441 gtgagactgc ccgcgtcggc gatggcccgc accgtcctca gatgccgcaa ctccagttcc
    43501 atgaggggag cttcgcggtc ccgacccggc agggcaagac tctggtccag acctgtcgcg
    43561 cggctcccgc ggtgccgtgc ggcggcctgc tcggggtgac gggtacggcc tccgcggggc
    43621 cgcgcggcgg cctgggcggg gcggaaggtc gggcctccgc agactcgcgc ggcggcctgg
    43681 gcggggcggg gggcacggct gcggcggggc tcgggggcgg ctccgggaag gccgtggcgg
    43741 aatccggggc gggggtctgt cgagcggggg gcgctcacga gatatcttga tgtcgagcaa
    43801 tgttacagac gtggagcgga gcacccggtg actgactcga ccatcatcta cacccacact
    43861 gacgaggccc cggccctggc gacgtactcg ttcctgcccg tggtccaggc gtacgcctcg
    43921 gcggccggcg tcagcgtcga gacccgcgac atctcgctgg ccgggcggat catcgcctcc
    43981 ttcccggagt acctccagga ggggcagcgc atcgacgacg ccctcgccga gctgggcgag
    44041 ctggcgaaga cgcccggcgc caacatcatc aagctgccga acatctcggc gtcgatcccg
    44101 cagctgaagg ccgccgtcgc ggagctgcag gagcagggct acgcgctgcc ggactacccg
    44161 gacgacccga agacggacga ggagcgcgag atccgcgccc gctacgacaa ggtcaagggc
    44221 agcgccgtca acccggtcct gcgcgagggc aactcggacc gccgcgcccc cgcgtcggtc
    44281 aagaactacg ccaaggcgca cccgcaccgc atgggcgcct ggacggccga ctccaagacg
    44341 aacgtggcga cgatgggcgc cgacgacttc cggtccaccg agaagtcggc ggtcgtcgcc
    44401 gaggacggct cgctgcgcat cgagctggcc ggcgaggacg gctcgacgac cgtgctgcgc
    44461 gagtccgtgc ccgtgctggc gggcgaggtc gtggacgcgt cggtgatgcg cgccgaggcg
    44521 ctgcgcgcct tcctctccga gcaggtcgcc cgcgccaagg ccgagggcgt gctgttctcc
    44581 gtccacctga aggcgacgat gatgaaggtc tcggacccga tcatcttcgg ccacgtggtc
    44641 cgcgcgttct tcccgaagac cttcgccgcc tacggcgacg tgctggccgg cgccggcctg
    44701 agcccgaacg acggcctcgg cggcatcctg aagggcctgg actccctgcc gcagggcgag
    44761 gagatcaagg cgtccttcga cgccgagctg gccgagggcc cggccctggc catggtcgac
    44821 tccgaccgcg gcatcaccaa cctgcacgta ccgagcgacg tcatcgtcga cgcgtcgatg
    44881 ccggccatga tccgcacctc cggccacatg tggggcccgg acggcaagga ggccgacacc
    44941 ctcgcggtcc tgcccgacag cagctactcc ggcgtgtacc aggccgtcat cgaggactgc
    45001 cgcgcccacg gcgccctcga cccggcgacc atgggctccg tgccgaacgt cggcctcatg
    45061 gcgcagaagg ccgaggagta cggcagccac gacaagacct tcgagatcgc gcaacccggc
    45121 accgtccgcg tggtcgacca ggccggcgag gtcgtcctgg agcagccggt cggccgcggc
    45181 gacatcttcc gcatgtgcca gacgaaggac gccccgatca gggactgggt gaagctcgcc
    45241 gtcacccgcg cccgcgccac cggcgacccg gccgtcttct ggctggacga gggccgcgcc
    45301 cacgacgccc ggctcatcga gaaggtcaag gcgtacctgc cggagcacga caccgagggc
    45361 ctccggatcg agatcatgcc gccggtcgag gcgacgaagt tctccctgga gcgcatccgc
    45421 cgcggcgaga acaccatctc cgtcaccggc aacgtgctgc gcgactacct gaccgacctg
    45481 ttcccgatcc tggagctcgg caccagcgcc aagatgctgt cggtcgtccc gctgatgaac
    45541 ggcggcggcc tcttcgagac gggtgcgggc ggctccgccc cgaagcacgt ccagcagctc
    45601 gtcaaggaga actacctgcg ctgggacagc ctcggcgagt tcctcgcgct ggcggtcagc
    45661 ttcgagcacc tctcgcaggt cacgggcaac gcccgtgcca aggtcctcgc ggacaccctg
    45721 gaccgcgcca cggccacctt cctcaacgag gacaagtcgc cgacccgccg cgtcggcggc
    45781 atcgacaacc gcggcagcca cttctacctc gccctgtact gggcgcagga gctggcgcgg
    45841 cagacggacg acgccgcgct cgccgaggcg ttcgggccgc tcgcgaagac cctcaccgag
    45901 caggagggcg cgatcgtcga ggagctgaac gcggtgcagg gcgagccggc cgacatcggc
    45961 ggctactacc agcccgaccc ggagaaggcg gcggcggtca tgcgcccgtc ccgcaccttc
    46021 aaccaggcgc tggggaccct ggcctgacgt cgccgctccg acggcggcgt cgagccaccc
    46081 gcgcgggccg cgccggacct cccgtccggc gcggcccgcg ccgcttcccc caccggcccg
    46141 cgccgcttcc cccaccgccc cccgccgtcc gcacgcgtcc cccgcaccgt ccgccacggg
    46201 cagtccggaa ccgcgaaccc ggcatatcct gaaatagacc tcgctatgtc ccgcggagcc
    46261 gagctgagga gtctcccgat ggcacgcgca gtgggtatcg acctcggtac gaccaactcg
    46321 gtggtgagcg tcctggaggg cggtgagccc gcggtcgtca cgaacacgga gggcgcgagg
    46381 accacgccgt ccgtcgtggg cttcgccaag aacggcgacg tgctggtggg cgaggtggcc
    46441 aagcggcagg ccgtcaccaa cgtggaccgc accgtccgct ccgtgaagcg gcacatgggc
    46501 gacacgggct ggcgcttccc cgagaacggc gacatcgacg gcaggcggta caccgcgcag
    46561 gagatctcgg cgcgcatcct gcagaagctg aagcgcgacg ccgagggcta cctcggcgag
    46621 gacgtcaggg acgccgtgat caccgtcccg gcgtacttca acgacgccga gcgcaccgcg
    46681 accaaggagg ccggcgagat cgcggggctg aacgtcctgc gcatcgtcaa cgagccgacc
    46741 gccgccgccc tggcgtacgg cctcgacaag gagagcgacc agacgatcct cgtcttcgac
    46801 ctcggcggcg gcaccttcga cgtgtcgctg ctggagatcg gcgacggcgt cgtcgaggtc
    46861 aaggccacca acggcgacac ccacctgggc ggcgacgact gggaccagcg gatcgtggag
    46921 cacctcgcgg gccgcttcag gaacgcgtac gggatcgaca tcaccaagga ccgcatggcg
    46981 acgcagcgcc tgcgcgaggc cgccgagaag gcgaagatcg agctgtccgc cgccaccgag
    47041 acctcggtca acctccccta cctgagcgcc tcggcggagg gcccgctgca cctggacgag
    47101 aagctcaccc gcgcccagtt ccagcagatg acctccgacc tgctggagcg gtgccaggtc
    47161 cccttccgga acgccgtgaa ggacgccggc atcgagatct ccgggatcga ccacgtcatc
    47221 ctcgtcggcg gctccacccg catgcccgcc gtggcggacc tggtgaagga gctgaccggc
    47281 aaggacccgc acaagggtgt gaacccggac gaggtcgtcg cgatcggcgc ctcgctccag
    47341 gccggtgtgc tcaagggcga ggtcaaggac gtcctgctgc tcgacgtcac cccgctgtcc
    47401 ctcggcatcg agaccaaggg cggcatcatg accaagctga tcgagcgcaa caccacgatc
    47461 ccgacgaagc gctccgagat cttcacgacg gcggaggaca accagccgtc ggtgcagatc
    47521 caggtctacc agggcgagcg cgagatcgcc gcgtacaaca agaagctcgg catgttcgag
    47581 ctgaccggtc tgcccccggc gccgcgcggc gtcccgcaga tcgaggtgtc cttcgacatc
    47641 gacgccaacg gcatcatgca cgtcacggcg aaggacctcg gcaccggcaa ggagcagaag
    47701 atgaccgtca ccggcggctc ctcgctcccg aaggacgaca tcgaccggat ggtccgcgag
    47761 gcggagcgcc acgcggagga ggaccacagg cgccgcgagg ccgccgaggc ccgcaaccag
    47821 ggcgagcagc tcgtctacca gaccgagaag ttcctcgccg accacgccga cggcacgggc
    47881 aaggtccccg gtgagatcag gaccgaggtc gagacggcgg tgaccgagct caaggagaag
    47941 ctgaagggcg acgacacggc gcagatccgc acggccgcgg agcgggtcgc ggccgtctcc
    48001 cagaagctcg gccaggccgt gtacgccgac gcccaggccg cccaggccgc gggcggcgcc
    48061 caggccggcc ccgagggcgg cgaggcggga ggccgggacg aggacgaggt ggtcgacgcc
    48121 gagatcgtcg acgaggacga ccgggcacgg cgcggaggtc ccgcgtgacg gccgcccgcg
    48181 ccggcgctcc ggacggggcg cctgccctgg tggtcgagtc ggcgggggac gggcgggccg
    48241 tcctggtgtt cgccggcgag ctggacgcgc accgggtggg cgcgctggag gaggcgctcg
    48301 acgatccccg gctgcgggac gccaccgtgt gggagctgct gatgcgcgac ctgacccgcc
    48361 tcgacctgcc gtgcgccttc gccctgctgc gggcggccac cgtccgcgac cccccggccg
    48421 ccctgcacgt gcggggggcg caccgcgccg tccgccgggc gctgcgggag gcgggcgcgg
    48481 acgcggtggc gacgttcgag ggctgagccc ccgcaggcac cgcccgcccg ccccgccgcc
    48541 accgtccgga cgtcccgccg ccaccgtccg gacgtcccaa ggccaccgcc cggacggcgg
    48601 gcgcggcccc ggccgcgggc gcggcctgag tacgcgtact caggcgcccg agcgcccgta
    48661 cgggcaccgt gcgggcatga gccctctgcc ctcctcaccg cccgtcgacc ccggctccgc
    48721 cggtccgcgc cgccgcgagc gggcccgccg gggccccgac gccgcggccg ggtgcgtgct
    48781 ggtcctgctg gagctgacgg ccctggcggt catccttctg gcctggccct tcctcgacca
    48841 cttcgaactg gacccgcagg cgccgcgcaa gcccttcacc ctctggcgct acctcccggc
    48901 ggtcgcggta ctcggcggcc tggtcctggt ggcggccgtc ctcgccgcgc gggcgcgcgc
    48961 cgtggtgacg gccgtgtccc agaccgccat gggggtgctg atcgcggcgg tgctgctggg
    49021 cgggacggcg ctccagcggc acgaggacga gcgcggccgc cccgtgcccg cgccgaccgg
    49081 cggcttctcc ggctgccgca gcggcggcga ctccgacgag tgtcccggcg ggtgaccggc
    49141 agggggcgag cccggtctcg cggacgtgcg tccgccgcgg cgggggccga tgatgtccgt
    49201 ggatcccccc tgtccggttc acgagaggga cggtggcagc agtggacacc ggcaccgcat
    49261 ccactccccc ggcggacggc gcccccgccg gcgcggagag cgccgctcgt gccgcgctgg
    49321 ccgggacggg cgtgcacctc atgcccccgc gcggcgcgct ggcctgcctg ggcgcggacg
    49381 cggcctcctg ggccggtttc gcggcgcact gggcggacct gacgcaggac gcgtacgcgg
    49441 cccggcgcgg cacccgccgg ctccgccgct acgggcactt ctcgctcgcg accgggaccg
    49501 gggagctgcg gctcctgccc cccaccggtt tcgtccagcc cgacggcacc aatccgctct
    49561 acacgtcggt ggaccggcgt ttcgacccgc tcaccgacgg cttcgccgcc gatccggtgc
    49621 tgctgcggct catcggtctg ctgggccggg tcgcgggcgc cctggactcc cccgaacggt
    49681 ggagcgtcaa ggtccatccc ttccgcgtcg tcgccacggc ggacggcgga ggggagccga
    49741 ctccggaggg ccggcaccgc gacggcgtca ccctggtgtc gtcgctgctc gtcggccggg
    49801 ggaacgccac cggaggcgag agcaccgtct acacccccga gggcggggag atcctgtcgg
    49861 tcacgctgcg cgagccggcg agcctgctcc tgtccgacga ccgccgcacc ctgcacggcg
    49921 tgtcgccggt ccggccggtc gaccccgcgc gcccggccca ccgggacgtc ctggtgacga
    49981 ccttcgcccc gggctgaccc cgccgggccg cccccgggcg cccggccgga ggcgtgtgcg
    50041 cgggcccggc gcggtgggcc ccggccgggc acgcgccgct acgtcccgct ccgggtgcgg
    50101 cgggggatga gcagccacgc cgccacggcg agggcgagcg gcaggaggct cacgaccacc
    50161 atggtgagcc gcagcccgtc cgtgaagtcc cagccgaggt cgagcccgga ctgccggagc
    50221 aggttcgggt cgtacccggc cgtgcccgga ctgcgtgcca tcgcgctgcg ggtggcgtcc
    50281 acggcctcct cggcctctgc cgcggacaat ccgcgctgct gcgcgtcgtc cagccactgc
    50341 cgctggaaga agaggttgag caggaggacg aagacggccg ggccgagggc gtagccgctc
    50401 atgccgaacg ccggctggac cgaggagacc gcgccggact tgcccggtgg ggcggcggag
    50461 aggatc
//
