BGC0000711: neomycin biosynthetic gene cluster from Streptomyces fradiae
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Location: 1 - 30,837 nt. (total: 30,837 nt).
This entry is originally from NCBI GenBank AJ843080.1.

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core biosynthetic genes
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000711
Short description neomycin biosynthetic gene cluster from Streptomyces fradiae
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (None)
Loci
AJ843080.1
via
Compounds
  • neomycin
Species Streptomyces fradiae [taxonomy]
References
Chemical products information
neomycin Evidence:
Copy SMILES
C23H46N6O13
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAH58684.1
 180 - 986 (-) putative neomycin phosphotransferase
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    • CAH58685.1
    		 995 - 2290 (-) hypothetical protein
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      • CAH58686.1
      		 2280 - 2801 (-) hypothetical protein
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        • CAH58687.1
        		 3662 - 4189 (-) hypothetical protein
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          • CAH58688.1
          		 4401 - 5423 (+) putative alcohol dehydrogenase
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            • CAH58689.1
            		 5502 - 6776 (+) L-glutamine:2-deoxy-scyllo-inosose aminotransferase
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              • CAH58690.1
              		 6947 - 8239 (+) putative 2-deoxy-scyllo-inosose synthase
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                • CAH58691.1
                		 8467 - 9651 (+) putative glycosyltransferase
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                  • CAH58692.1
                  		 9648 - 11639 (+) putative exporter
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                    • CAH58693.1
                    		 11636 - 13420 (+) putative exporter
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                      • CAH58694.1
                      		 13629 - 15254 (+) putative sugar dehydrogenase
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                        • CAH58695.1
                        		 15428 - 16327 (+) putative Fe-S oxidoreductase
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                          • CAH58696.1
                          		 16324 - 17025 (+) putative phosphomutase
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                            • CAH58697.1
                            		 17022 - 17273 (+) hypothetical protein
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                              • CAH58698.1
                              		 17266 - 18366 (+) hypothetical protein
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                                • CAH58699.1
                                		 18359 - 19198 (+) hypothetical protein
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                                  • CAH58700.1
                                  		 19396 - 21378 (-) putative ribosyltransferase
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                                    • CAH58701.1
                                    		 21495 - 22745 (+) putative aminomutase
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                                      • CAH58702.1
                                      		 22831 - 26772 (+) hypothetical protein
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                                        • CAH58703.1
                                        		 26934 - 27797 (-) putative aminoglycoside N-acetyltransferase
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                                          • CAH58704.1
                                          		 28177 - 30837 (-) putative LuxR regulator
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                                            Biosynthesis information
                                            Annotation changelog

                                            Entry version: 4

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-10-07
                                            Update chemical activity to schema version 2.11
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 3

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2022-09-15
                                            Updated bioactivity data
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 2

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2019-10-16
                                            Migrated from v1.4
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                            Entry version: 1

                                            Date
                                            Changes
                                            Submitters
                                            Reviewers
                                            2015-06-12
                                            Submitted
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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