LOCUS       BGC0000712             48169 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptomyces rimosus subsp. paromomycinus genomic region of the
            paromomycin biosynthesis gene cluster, strain NRRL 2455.
ACCESSION   BGC0000712
VERSION     BGC0000712
KEYWORDS    .
SOURCE      Streptomyces paromomycinus
  ORGANISM  Streptomyces paromomycinus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:05:30
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(<1..242)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFQ5"
                     /note="ORF SriG07.16c"
                     /product="putative P450 heme thiolate protein"
                     /protein_id="CAF32360.1"
                     /transl_table=11
                     /translation="MSAPSPQQRERGSSHVSTPPQAPASGQAAHEEPLPRYPFSTRGDR
                     LAPELDELRGRCPVARVNTNSGEQAWLVTGYELAR"
     source          1..48169
                     /db_xref="taxon:92743"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces paromomycinus"
                     /strain="NRRL 2455"
                     /type_material="type strain of Streptomyces rimosus subsp.
                     paromomycinus"
     subregion       1..48169
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000712"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..48169
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /product="2dos"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /rules="((DOIS or DHQ_synthase or ValA or salQ) and
                     DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     cand_cluster    1..26262
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /kind="neighbouring"
                     /product="NRPS-like"
                     /product="2dos"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..24849
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[1516:4849]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1517..4849
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..24849
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     regulatory      complement(249..251)
                     /note="ORF SriG07.16c"
                     /regulatory_class="ribosome_binding_site"
     CDS             complement(279..1520)
                     /codon_start=1
                     /db_xref="GOA:Q2MFQ4"
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002397"
                     /db_xref="UniProtKB/TrEMBL:Q2MFQ4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 378.7; E-value:
                     5.4e-115)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SriG07.17c"
                     /product="putative cytochrome P450 hydroxylase"
                     /protein_id="CAF32361.1"
                     /sec_met_domain="p450 (E-value: 7.3e-16, bitscore: 49.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRPEAAVPDAAAPEALIPVPETAPGTPGPPCAYARLRTEAPVVK
                     AQLPNGETGWLISRYEDARAAFADPRLVRPLLSAWPPREGADAPPPCLPTFLEMTGAHH
                     ERVRRTVLPMFGRRQLSFMEPRIRAMAGDLVDTMVAGSDGGPADLVASYAEPLPLRVLC
                     ETVGLPYEDREIYLPHTLALLGAAGLTMEEVLAALYALQDYAGDLIARKERDGDGEDYI
                     RLLLALARRPDSEITRDDVVSFVVTMLMAGYKTNIQHTGNALLALLTHPEQLRTLRAAP
                     ERIPTAVEELLRYVPLMNAINILVATEDFTLHGQHIRAGDAVVPVPASANRDPAAFVEP
                     DRLDLARTPNAHIAFGHGPHACTGANLTRMQLTIAIQVLLERLPDLELAVPAEKIDWDQ
                     STPLRAPARLPVRW"
     CDS             complement(1517..4849)
                     /NRPS_PKS="Domain: AMP-binding (36-437). E-value: 2.5e-96.
                     Score: 314.6. Matches aSDomain:
                     nrpspksdomains_CAF32362.1_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (552-620). E-value: 4.3e-10. Score:
                     31.6. Matches aSDomain: nrpspksdomains_CAF32362.1_PCP.1"
                     /NRPS_PKS="Domain: TD (664-905). E-value: 1.8e-90. Score:
                     294.2. Matches aSDomain: nrpspksdomains_CAF32362.1_TD.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MFQ3"
                     /db_xref="InterPro:IPR000873"
                     /db_xref="InterPro:IPR004829"
                     /db_xref="InterPro:IPR006163"
                     /db_xref="InterPro:IPR009081"
                     /db_xref="InterPro:IPR010071"
                     /db_xref="InterPro:IPR010080"
                     /db_xref="InterPro:IPR013120"
                     /db_xref="UniProtKB/TrEMBL:Q2MFQ3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     326.1; E-value: 5.1e-99)"
                     /gene_kind="biosynthetic"
                     /note="ORF Sri.G07.18c"
                     /product="putative non-ribosomal peptide synthetase"
                     /protein_id="CAF32362.1"
                     /sec_met_domain="AMP-binding (E-value: 9.4e-101, bitscore:
                     328.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.1e-66, bitscore:
                     214.9, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTYVSSRPLSKRPQVPGARTPAPGYPRDSRIPELFEAQAAALP
                     QAPAARHGDRTLTYGQLDAHADALADRLAAGGVRPGDLIGVCGSRSLEALVALLGILKA
                     GCAYVPLDEELPPARLRAMAEDAGISAAVTLPGSTRRVRGLRVSVEVGSLGRPAPERAS
                     GPAPDRATGSAADCAYVAFTSGTTGRPKPVALSHRGVVRLVLSDPGLTPPGPGDGVLHA
                     YSLSSDASTIEIWGALLTGACLVVADREELLSPTALERLLRAGGVTVAYLTTSVFHLVA
                     RTRPEALAGLRFVSAGGEAMDPRLANAVLAACPRTTVVNFYGPTENAVVSTAHVLTPLP
                     EDAAHVPLGRPFGASTCHVLRADGSPARPGEEGELYVGGDGLALGYLGDPQLTAERFVT
                     LPAVEPDGPLYRTGDRAVRHADGLLEYRGRLDRQVKLRGARIELDEVETRLRAHPEVGE
                     AAVEVDGHSLTAYVTATVPGRPLPLADLRAYCAKWLPPQAVPALIPLDRFPVTSGGKID
                     RSRLKPTAPPPGPEDTAEAARRPDEPEATDGLSGLLSEVWHQVLRVRPTPRDDFFLLGG
                     DSLLASETVTRTLAVLGLDAALGSTLIRALLAAPTLESFTAAVRGVRGGTGGPAGGQEP
                     AVDFAAETGLGFALPPAEGPAPNPHDPEDVLLTGASGFVGGFLLHRLLHATAARVHCPV
                     RATSPAHARQRVRTALTRYGLHLDEADWQRVECFPGDLTQPRLGLDHERADALAQRLDL
                     IVHNGARVNFLYPYQQLRPANVDGTREVVRIAARRRVPVHFVSTVAVVAGFGTAGVREV
                     DEDLPPAHADGLTMGYAESKWVAEGVLRQAAAQGLPVAVYRPYEVTGDRTHGACNTETA
                     ICSLFKMIADTGVAPDIKLPMDFVPVDHLAESLVHIATHRPADGRVYHLTNPRPAMLSD
                     VLDRMRAAGFTLRTLPYDAWVGELVRHVAENPTSATAPFVSLCVDRSRTADMSVKEMYL
                     KGTFPVLGRRNAEEALAGSGLHCPPVDSALLDRYLEYFFTSGYLTRPAAGPGPESEAER
                     IPEDEPVSGTEPISGTEPISAAEPISGTEPISAAGPISGTEPIPAAEPISGTAAAARTE
                     RSR"
     regulatory      complement(1529..1532)
                     /note="ORF SriG07.17c"
                     /regulatory_class="ribosome_binding_site"
     aSDomain        complement(2135..2857)
                     /aSDomain="TD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAF32362.1_TD.1"
                     /evalue="1.80E-90"
                     /label="CAF32362.1_TD.1"
                     /locus_tag="CAF32362.1"
                     /protein_end="905"
                     /protein_start="664"
                     /score="294.2"
                     /tool="antismash"
                     /translation="VLLTGASGFVGGFLLHRLLHATAARVHCPVRATSPAHARQRVRTA
                     LTRYGLHLDEADWQRVECFPGDLTQPRLGLDHERADALAQRLDLIVHNGARVNFLYPYQ
                     QLRPANVDGTREVVRIAARRRVPVHFVSTVAVVAGFGTAGVREVDEDLPPAHADGLTMG
                     YAESKWVAEGVLRQAAAQGLPVAVYRPYEVTGDRTHGACNTETAICSLFKMIADTGVAP
                     DIKLPMDFVPVDHLAESLV"
     aSModule        complement(2135..4741)
                     /complete
                     /domains="nrpspksdomains_CAF32362.1_AMP-binding.1"
                     /domains="nrpspksdomains_CAF32362.1_PCP.1"
                     /domains="nrpspksdomains_CAF32362.1_TD.1"
                     /final_module
                     /locus_tags="CAF32362.1"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     protocluster    2684..26262
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[12683:16262]"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      12684..16262
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="2"
     cand_cluster    2684..26262
                     /candidate_cluster_number="3"
                     /contig_edge="True"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /kind="single"
                     /product="2dos"
                     /protoclusters="2"
                     /tool="antismash"
     aSDomain        complement(2990..3193)
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAF32362.1_PCP.1"
                     /evalue="4.30E-10"
                     /label="CAF32362.1_PCP.1"
                     /locus_tag="CAF32362.1"
                     /protein_end="620"
                     /protein_start="552"
                     /score="31.6"
                     /tool="antismash"
                     /translation="LSEVWHQVLRVRPTPRDDFFLLGGDSLLASETVTRTLAVLGLDAA
                     LGSTLIRALLAAPTLESFTAAVR"
     misc_feature    complement(3500..3502)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       complement(3509..3574)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAF32362.1_0005"
                     /evalue="6.80E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="CAF32362.1"
                     /protein_end="447"
                     /protein_start="425"
                     /score="28.0"
                     /tool="antismash"
                     /translation="YRGRLDRQVKLRGARIELDEVE"
     aSDomain        complement(3539..4741)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAF32362.1_AMP-binding.1"
                     /evalue="2.50E-96"
                     /label="CAF32362.1_AMP-binding.1"
                     /locus_tag="CAF32362.1"
                     /protein_end="437"
                     /protein_start="36"
                     /score="314.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FEAQAAALPQAPAARHGDRTLTYGQLDAHADALADRLAAGGVRPG
                     DLIGVCGSRSLEALVALLGILKAGCAYVPLDEELPPARLRAMAEDAGISAAVTLPGSTR
                     RVRGLRVSVEVGSLGRPAPERASGPAPDRATGSAADCAYVAFTSGTTGRPKPVALSHRG
                     VVRLVLSDPGLTPPGPGDGVLHAYSLSSDASTIEIWGALLTGACLVVADREELLSPTAL
                     ERLLRAGGVTVAYLTTSVFHLVARTRPEALAGLRFVSAGGEAMDPRLANAVLAACPRTT
                     VVNFYGPTENAVVSTAHVLTPLPEDAAHVPLGRPFGASTCHVLRADGSPARPGEEGELY
                     VGGDGLALGYLGDPQLTAERFVTLPAVEPDGPLYRTGDRAVRHADGLLEYRGRLDRQVK
                     LR"
     CDS_motif       complement(3659..3745)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAF32362.1_0004"
                     /evalue="8.60E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="CAF32362.1"
                     /protein_end="397"
                     /protein_start="368"
                     /score="46.8"
                     /tool="antismash"
                     /translation="PGEEGELYVGGDGLALGYLGDPQLTAERF"
     CDS_motif       complement(4112..4147)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAF32362.1_0003"
                     /evalue="5.10E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="CAF32362.1"
                     /protein_end="246"
                     /protein_start="234"
                     /score="-1.5"
                     /tool="antismash"
                     /translation="WGALLTGACLVV"
     CDS_motif       complement(4259..4318)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAF32362.1_0002"
                     /evalue="9.70E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="CAF32362.1"
                     /protein_end="197"
                     /protein_start="177"
                     /score="24.3"
                     /tool="antismash"
                     /translation="AYVAFTSGTTGRPKPVALSH"
     CDS_motif       complement(4514..4555)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CAF32362.1_0001"
                     /evalue="3.50E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="CAF32362.1"
                     /protein_end="112"
                     /protein_start="98"
                     /score="20.0"
                     /tool="antismash"
                     /translation="LGILKAGCAYVPLD"
     misc_feature    complement(4817..4819)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     regulatory      complement(4857..4860)
                     /note="ORF SriG07.18c"
                     /regulatory_class="ribosome_binding_site"
     CDS             complement(4908..5384)
                     /codon_start=1
                     /db_xref="GOA:Q2MFQ2"
                     /db_xref="InterPro:IPR000659"
                     /db_xref="InterPro:IPR011576"
                     /db_xref="InterPro:IPR012349"
                     /db_xref="UniProtKB/TrEMBL:Q2MFQ2"
                     /note="ORF SriD03.11c"
                     /product="hypothetical protein"
                     /protein_id="CAF32363.1"
                     /transl_table=11
                     /translation="MSRPDRERFLAEPRVGVLGVTDSRGGDRGPLIVPVWYSYEPGGEV
                     VVETGRQTVKAQLLRAAGRFSLCAQDEGRPYRYVSVEGPVTAIDDPLDPALREALAHRY
                     LDAEEARGYLAATSGQLTEDIAFRMRPQHWRSADFAAFAADFAEGGAGEETVPR"
     CDS             5831..6613
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFQ1"
                     /note="ORF Sri.D03.12"
                     /product="hypothetical protein"
                     /protein_id="CAF32364.1"
                     /transl_table=11
                     /translation="MATSCAAGPGASHTASVDTDTESPATPPAPTTASGPADQEQFDER
                     ESAADARQCLADAREDVTGERDRLTGPRESVADPRQHFLDAREIHADRLSRLTEITVPT
                     RRKRSFEAIGRARVLLASSQVRLDRTEATLSHTESGDARERRSAEQEIAASIRRAFGDE
                     MSQQAALESLVGQLQARFRTAAAALAEAQDQLAHHHERLAADGHPDADDHRVRAERARR
                     AARRVRAAVQTRAAEPTTAPPKDDRSAESPALAPDTGT"
     CDS             6792..7202
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFQ0"
                     /note="ORF SriD03.13"
                     /product="hypothetical protein"
                     /protein_id="CAF32365.1"
                     /transl_table=11
                     /translation="MTTTLEPPGARTRNRARTRTRTRTRTRTDRVPLSLTVSSWAVPVM
                     VVGQFALLSGIPVAIALAGALRQVPDRAVRWTAALLAVTYAVPLTVWLTRADPARSLSK
                     DMHPAFAVLMVVASAGLVVALHRARTRRPAAR"
     regulatory      7274..7281
                     /note="ORF SriD03.13"
                     /regulatory_class="ribosome_binding_site"
     CDS             7286..7921
                     /NRPS_PKS="Domain: Polyketide_cyc2 (53-203). E-value:
                     1.1e-19. Score: 63.0. Matches aSDomain:
                     nrpspksdomains_CAF32366.1_Polyketide_cyc2.1"
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFP9"
                     /note="ORF SriD03.14"
                     /product="putative polyketide cyclase /reductase"
                     /protein_id="CAF32366.1"
                     /transl_table=11
                     /translation="MPALRSTGLRAALLTVPLALGLLGTAAVPAGATPSHPAKSLTCRG
                     KGVDPDAAVRHRTETVIHAPLHTIWKLQTDVARWPAWQSSVETAERLDHGPLRRGSAFR
                     WTTPIPPNPATPATSLEITSTVEQLRHGSCLRWTGPASAEGLRIDGVHVWNFTKVPGGV
                     RVSTEETHTGDQVEANVPAATRILREGLEKWLRELTAAAEVCAHHQAR"
     aSDomain        7445..7894
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CAF32366.1_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.10E-19"
                     /label="CAF32366.1_Polyketide_cyc2.1"
                     /locus_tag="CAF32366.1"
                     /protein_end="203"
                     /protein_start="53"
                     /score="63.0"
                     /tool="antismash"
                     /translation="VRHRTETVIHAPLHTIWKLQTDVARWPAWQSSVETAERLDHGPLR
                     RGSAFRWTTPIPPNPATPATSLEITSTVEQLRHGSCLRWTGPASAEGLRIDGVHVWNFT
                     KVPGGVRVSTEETHTGDQVEANVPAATRILREGLEKWLRELTAAAE"
     CDS             complement(7997..9115)
                     /codon_start=1
                     /db_xref="GOA:Q2MFP8"
                     /db_xref="InterPro:IPR003198"
                     /db_xref="UniProtKB/TrEMBL:Q2MFP8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) pgm_amidino"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SriD03.15c"
                     /product="putative amidinotransferase"
                     /protein_id="CAF32367.1"
                     /sec_met_domain="pgm_amidino (E-value: 3.3e-101, bitscore:
                     330.0, seeds: 95, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPSATAAGTEESPAPPVNSYTEWDPLEEIIVGRLDGATIPSSH
                     PVVTCNIPPWAARLQGLAAGFKYPRVLIERAQRELDAFVALLESLDVTVRRPDAVDHRQ
                     RFGTPDWSSRGFCNTCPRDSLLVIGDEIIETPMAWPCRYFEAHSYRTVVKDYFRRGARW
                     TAAPRPQLTDELFDAEFRVPEAGEPMRYILTEFEPVFDAADFVRAGRDLFVTRSNVTNR
                     MGIDWLRRHLGPGYRIHEIESRCRTPMHIDTTFVLLAPGKVLVNPEYIDVDRLPDVLSS
                     WDVLIAPEPTPVDGRLLRLTSLCGKWLSMNVLMVDEKRVIAERHHTGMLRALEKWGFEP
                     IPCDLLHYAPFGGSFHCATLDVRRRGTLQTYV"
     regulatory      complement(9125..9127)
                     /note="ORF SriD03.15"
                     /regulatory_class="ribosome_binding_site"
     CDS             complement(9285..9794)
                     /codon_start=1
                     /db_xref="GOA:Q2MFP7"
                     /db_xref="InterPro:IPR003594"
                     /db_xref="UniProtKB/TrEMBL:Q2MFP7"
                     /gene_functions="other (smcogs) SMCOG1054:hypothetical
                     protein (Score: 68.4; E-value: 1.3e-20)"
                     /gene_kind="other"
                     /note="ORF SriD03.16c"
                     /product="putative regulator protein"
                     /protein_id="CAF32368.1"
                     /transl_table=11
                     /translation="MTTHPAPTVHDVRHAETGAEQPATSLDAFAVCALSGAYSAVAEAR
                     RFTAATLEGWGVCAPVVSDAVLVVSELTGNALRHAVPRHPDAESPRPELVCAACLALAH
                     QDAGVLCAVSDSSRAVPALAAPDPLAEEGRGLWIVDRLSESWGWTRPDRTGKTVWAQLP
                     VPRPTG"
     regulatory      complement(9801..9804)
                     /note="ORF SriD03.16"
                     /regulatory_class="ribosome_binding_site"
     regulatory      9977..9983
                     /note="ORF SriD03.18"
                     /regulatory_class="ribosome_binding_site"
     CDS             9991..10233
                     /codon_start=1
                     /db_xref="InterPro:IPR007278"
                     /db_xref="UniProtKB/TrEMBL:Q2MFP6"
                     /note="ORF SriD03.17"
                     /product="putative regulator protein"
                     /protein_id="CAF32369.1"
                     /transl_table=11
                     /translation="MESLPNGICASAIEGAVWRKSSRSNPNGNCVELAVLADGGVAVRN
                     SRHTGGPALVYTRDEIAAFVQGAKDGDFDDLAGTG"
     regulatory      10312..10318
                     /note="ORF SriD03.17"
                     /regulatory_class="ribosome_binding_site"
     CDS             10324..11238
                     /codon_start=1
                     /db_xref="GOA:Q2MFP5"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="UniProtKB/TrEMBL:Q2MFP5"
                     /note="ORF SriD03.18"
                     /product="putative DNA-binding protein"
                     /protein_id="CAF32370.1"
                     /transl_table=11
                     /translation="MVAAQPGRVPPLRRHIEHPRGGPTVLRIILGTHLRRLREAAGVTR
                     EAAGDAIRGSHAKISRLELGRVGCKERDVADLLTLYRVTDEQERAEFLALARGTSTPGW
                     WHRYNDVLPTWFETLIGLEEAASVIRTYEVQFVPGLLQTPEYAYAVCRLGNPQASRKEV
                     DRRVELRLQRQALLTAPGAPRLWAVLDEASLRRPLGGPDVMSGQLRHLLAMSQLPNVTV
                     QVAPFHLGGHAAAGGPITILRFLEPDLPDIVYLEQLTSALYLDKRDDVDHYLAVMDRLS
                     AQAESPRGTQAILEELIGGTEGD"
     CDS             complement(11262..12077)
                     /codon_start=1
                     /db_xref="InterPro:IPR006764"
                     /db_xref="UniProtKB/TrEMBL:Q2MFP4"
                     /gene_functions="other (smcogs) SMCOG1292:hypothetical
                     protein (Score: 339.7; E-value: 1.6e-103)"
                     /gene_kind="other"
                     /note="ORF SriD03.19"
                     /product="hypothetical protein"
                     /protein_id="CAF32371.1"
                     /transl_table=11
                     /translation="MSQEVRPQSGTVDVSVPSVARMYDYYLGGKDNYAVDREACEELNK
                     VVPSTQVLAVNNRRFLRRVVRWLAQEQGIRQFIDHGSGLPTQDNVHQVAQRVAPESRVV
                     YVDNDPIVLAHGRALLEENRNTAVIQADMRDTDGILGHPEVARLIDFDQPVAALFVSVL
                     HCIPDEDDPAGLIRRVAERLAPGSFLVVCQLVSEDAATRDFVTEFMRVSTQGQWGRVRT
                     AAELGSFLEGLEILEPGLVEVSTWKPDADIGPKQLTMEWIEYGGVARKR"
     misc_feature    <12007..>31940
                     /note="paromomycin gene cluster; Location changed from
                     '(7997.12007)..>31940' to '<12007..>31940'"
     regulatory      complement(12084..12090)
                     /note="ORF SriD03.16"
                     /regulatory_class="ribosome_binding_site"
     regulatory      12671..12675
                     /gene="parE"
                     /note="ORF SriD03.20"
                     /regulatory_class="ribosome_binding_site"
     gene            12671..13703
                     /gene="parE"
     CDS             12684..13703
                     /NRPS_PKS="Domain: PKS_ER (15-258). E-value: 7.6e-10.
                     Score: 30.2. Matches aSDomain:
                     nrpspksdomains_parE_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MFP3"
                     /db_xref="InterPro:IPR002085"
                     /db_xref="InterPro:IPR002328"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="UniProtKB/Swiss-Prot:Q2MFP3"
                     /function="biosynthesis of 2-deoxystreptamine-containing
                     aminoglycosides"
                     /gene="parE"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_zinc_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADSI-DH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 306.7; E-value:
                     2.8e-93)"
                     /gene_kind="biosynthetic"
                     /note="ORF SriD03.20"
                     /product="putative 3-amino-2,3-dideoxy-scyllo-inositol
                     1-dehydrogenase"
                     /protein_id="CAF32372.1"
                     /sec_met_domain="ADSI-DH (E-value: 2.1e-160, bitscore:
                     524.4, seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 5.6e-29, bitscore: 91.7,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 5.4e-18, bitscore:
                     56.7, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALMFKAPLQAVLTERDVPEPAPGEALVKLAYNSICGSDLSFYK
                     GVWHGFTYPVVPGHEWSGTVVEAGGGAADLVGQNVVGDLTVACGSCRHCTVGKPTLCAD
                     LQELGFTRDGACAEYMTVPTGNLHRLPEGLSLREATQVEPLAVALNAVDRLAVTAGEKV
                     AITGAGGIGLLLAQAVRLRGAEVTVLAEPVTERRQAAHALGVPHTVGGDPGELVGFVEK
                     HPELTPDVVLEASGYPLAVQEAVEAVRSGGRIGLIGYRIEEAATMAPHHIVVKVLSLQA
                     SMGPGDRFGEAIELLAAGAVDVDALLSHEFGLADHDRALDVALRRADGNTRSYFNLRA"
     aSDomain        12729..13457
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_parE_PKS_ER.1"
                     /evalue="7.60E-10"
                     /label="parE_PKS_ER.1"
                     /locus_tag="parE"
                     /protein_end="258"
                     /protein_start="15"
                     /score="30.2"
                     /tool="antismash"
                     /translation="ERDVPEPAPGEALVKLAYNSICGSDLSFYKGVWHGFTYPVVPGHE
                     WSGTVVEAGGGAADLVGQNVVGDLTVACGSCRHCTVGKPTLCADLQELGFTRDGACAEY
                     MTVPTGNLHRLPEGLSLREATQVEPLAVALNAVDRLAVTAGEKVAITGAGGIGLLLAQA
                     VRLRGAEVTVLAEPVTERRQAAHALGVPHTVGGDPGELVGFVEKHPELTPDVVLEASGY
                     PLAVQEAVEAVRSGGRIGLIG"
     regulatory      13744..13751
                     /gene="parS"
                     /note="ORF SriD03.21"
                     /regulatory_class="ribosome_binding_site"
     gene            13744..15033
                     /gene="parS"
     CDS             13759..15033
                     /NRPS_PKS="Domain: Aminotran_1_2 (30-180). E-value:
                     6.5e-08. Score: 23.9. Matches aSDomain:
                     nrpspksdomains_parS_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MFP2"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="UniProtKB/Swiss-Prot:Q2MFP2"
                     /gene="parS"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     389.9; E-value: 2.1e-118)"
                     /gene_kind="biosynthetic"
                     /note="ORF SriD03.21; conserved in all gene clusters for
                     aminoglycosides with diaminocyclitol units"
                     /product="putative bifunctional L-glutamine:ketocyclitol
                     aminotransferase I and II"
                     /protein_id="CAF32373.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 3.5e-107,
                     bitscore: 350.1, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.6e-08, bitscore:
                     23.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSLAVQGGSPVRTRPWPLWPQPAPGAVRALDGVLTSGRWSISG
                     PYRGAASQERRFAQAFAAYNGVEHCVPAASGTASLMLAMEACGIGAGDEVIVPGLSWVA
                     SGSTVLGVNAVPVFCDVDPDTLCLDPAAVESALTERTKAIVVVHLYSAVAAMDALRALA
                     DRHGLPLLEDCAQAHGAEYRGVKVGALATAGTFSMQHSKVLTSGEGGAVITRDAEFARR
                     VEHLRADGRCLAGQPVGDGQMELVETGELMGSNRCVSEFQAALLVEQLGVLDEQNERRR
                     RNAALLDKLLADEGYRPQTTSEGTSTRTYYTYAARLPEGELTHVDAAAVGEALTAELGF
                     PVAPCYAPITRNRLYDPRSRGRFALGVQHESRIDPKRFELPVCEEAARRTVTVHHAALL
                     GDESDMHDIATAFGKVVRHGALLTG"
     aSDomain        13849..14298
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_parS_Aminotran_1_2.1"
                     /evalue="6.50E-08"
                     /label="parS_Aminotran_1_2.1"
                     /locus_tag="parS"
                     /protein_end="180"
                     /protein_start="30"
                     /score="23.9"
                     /tool="antismash"
                     /translation="ALDGVLTSGRWSISGPYRGAASQERRFAQAFAAYNGVEHCVPAAS
                     GTASLMLAMEACGIGAGDEVIVPGLSWVASGSTVLGVNAVPVFCDVDPDTLCLDPAAVE
                     SALTERTKAIVVVHLYSAVAAMDALRALADRHGLPLLEDCAQAHGA"
     regulatory      15093..15099
                     /gene="parC"
                     /note="ORF SriD03.22"
                     /regulatory_class="ribosome_binding_site"
     gene            15093..16262
                     /gene="parC"
     CDS             15102..16262
                     /codon_start=1
                     /db_xref="GOA:Q2MFP1"
                     /db_xref="InterPro:IPR002658"
                     /db_xref="UniProtKB/Swiss-Prot:Q2MFP1"
                     /function="biosynthesis of aminoglycosides with
                     2-deoxystreptamine as a cyclitol moiety"
                     /gene="parC"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DHQ_synthase"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DOIS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183:3-dehydroquinate synthase (Score: 370.1; E-value:
                     1.6e-112)"
                     /gene_kind="biosynthetic"
                     /note="ORF SriD03.22"
                     /product="putative 2-deoxy-scyllo-inosose synthase /
                     cyclase"
                     /protein_id="CAF32374.1"
                     /sec_met_domain="DOIS (E-value: 6.2e-173, bitscore: 566.0,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 2e-72, bitscore:
                     234.9, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVTAITMEDTSFPYRLGTECAEEIVARLGERAASRYLVVCDTTV
                     AALYGRDLVARLEKDAGPAVLLTHPAGEVHKRIGTVGDLAEQALAAGADRRSVVVALGG
                     GITGNIAGLLASLLFRGITLVHVPTTVVAMLDSVLSLKQAVNASFGKNLVGTFYQPAEV
                     LADTAMLRTLPARELRSGMGEVVKNALAIRPSMIERLAAELRPDARYEDAAMRWIIEES
                     VAAKAQVTGADKHERRDGLVLEYGHTTGHAIEHAARGEVAHGAGVAIGMIVAAEVSRLL
                     GHASGDLVGLHRELVAKAGLEGSVPALVDPADVKHWLTYDNKRGYMPCPPAATPMVLLS
                     APGEVLRSGPLPLVPVPLELLGRAVDALAAPAGQSAGAERLSPAPA"
     regulatory      16317..16320
                     /gene="parM"
                     /note="ORF SriD03.23"
                     /regulatory_class="ribosome_binding_site"
     gene            join(16317..16320,16326..17579)
                     /gene="parM"
     CDS             16326..17579
                     /codon_start=1
                     /db_xref="GOA:Q2MFP0"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q2MFP0"
                     /gene="parM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 271.1;
                     E-value: 2.9e-82)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SriD03.23; conserved in gene clusters for
                     aminoglycosides with a paromamine pseudodisaccaride unit
                     such as neomycins, kanamycins, gentamicins, fortimicins;
                     putative paromamine synthase"
                     /product="putative UDP-NAc-glucosamine:2-deoxystreptamine
                     4-glycosyltransferase"
                     /protein_id="CAF32375.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.9e-32,
                     bitscore: 103.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLRLTPFFHHDQVESWPAEYDAVGGMQVQILRLSRELAARGVE
                     QQVLTVGFPGLPKRRLDRPGLVVRVTRAPLPPIRSQLTGLVGLNQAWLAGALAACVRLR
                     RRWRPDLIHVHADGQLWALLAGPLAARVMGVPYCLTLHCSRLSVYEPMSRVDQFQHRLV
                     RAVESHAVRRAARVSALTSRTAGVVARALSMDPASIDIVPDSVGDLSPRPAGEVAGLRR
                     SLEIAEGAALVGYVGRVAHEKGWRDFVALARRWQSLPGTPPAVFLVVGDGPQRERMGKA
                     VADAGLTDRFRFTGFLPHADIPAVMTALDVLVMPSAHEELGGSAIEAMMCGTPVAGYSV
                     GGLRETVGTVTPGLLVPRGDVAALTEAVRGVVEEPEGPRGRVAGARERLGTAYGSGSAT
                     DRALEHYAHALRAAGSAR"
     gene            17576..19390
                     /gene="parT"
     CDS             17576..19390
                     /codon_start=1
                     /db_xref="GOA:Q2MFN9"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="UniProtKB/TrEMBL:Q2MFN9"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /gene="parT"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 593.8; E-value:
                     5.9e-180)"
                     /gene_kind="transport"
                     /note="ORF SriD03.24"
                     /product="putative ABC transporter, ATP-binding protein"
                     /protein_id="CAF32376.1"
                     /transl_table=11
                     /translation="MSAPPARTGSLWRCARYLRPHRWLMVGACAAALGSMLAGLSMPLV
                     LQRLVDGPVAHKDMAALPWTLIGFTVLGCLEAVLLGARRLLVVRPSTRLETTLRAGLFR
                     HVQRLPSSFHTRWSSGQLLSRTVSDIAELGRFFAFSAVYLLVNTAALVAGLAVLAYLSP
                     FLALIVLVTYLPMVLATILFEKRFHVAARSAQDQSGDLTTTVEESVLGIRVLKAFGRGP
                     ETVRRFTAQARALRRTELRKISLTAALWWLITALPEVGIVALMGFGGYGTATGTLTLGT
                     LMAAITVATYMRWPADTLGWLIADASTAASAADRYWQLRDVPLAVREPAAPRPLASPVR
                     GELRVEDVHYRLPGAGDAVLRGIDLTVRPGSTLALVGATGSGKSTLVSLLSRLDDPTHG
                     RITLDGTDLRDLSLDALRSVVTCAFDDPVLFSGTVRDNVALGLPPEERDDARIWEALRL
                     AHAADFVAALPEQLDTRVGEEGVGLSGGQRQRLALARAVLPRPAVLVLDNALSALDVHT
                     EREVEAALRTVMANVTTVLVAHRPATLRAADRVALIADGRVAATGTHDELMATDRRYRH
                     LLRSPVNDLVPDGPQGPPSQDPARKVRA"
     gene            19390..21276
                     /gene="parU"
     CDS             19390..21276
                     /codon_start=1
                     /db_xref="GOA:Q2MFN8"
                     /db_xref="InterPro:IPR001140"
                     /db_xref="InterPro:IPR003439"
                     /db_xref="InterPro:IPR003593"
                     /db_xref="InterPro:IPR011527"
                     /db_xref="UniProtKB/TrEMBL:Q2MFN8"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /gene="parU"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 369.9; E-value:
                     4e-112)"
                     /gene_kind="transport"
                     /note="ORF SriD03.25"
                     /product="putative ABC transporter, ATP-binding protein"
                     /protein_id="CAF32377.1"
                     /transl_table=11
                     /translation="MPEDRQENDTAAPRPSGAPDVDRAADEADGRPDDRRLRERRNQLL
                     RTLLAPERRRLTRAVGLALLENVCALVTPLLIAAAIDRGVPAAADGRWGPLTAYAALAL
                     TAGTATATLRYGFLRYSGNIAQTLLFRLRCRTFAHAVRLPLSYHEAAPSGSVVARLSSD
                     VESVEEVLEMGLDGLFSALFSMVGTVAVMLWLDLPMAAVVLALFIPLYLLTRWFRDRSR
                     RAYRRTRGATERIVQHTGETYNGIRAVQAFRKEGENTARLREMDATYATARAASGRVSA
                     FFSGGVKLIGNLSLALLLALGAFRIASGHLEAGALTAFLLYVHRLYDPIDELASFANAF
                     SAASAGLERIGVLFHAPDTLPEPADPRPLPAVAAPGRVRFEDVRFRYTAASPHVLAGLD
                     LDLAPAETVALVGTTGAGKSTLAKLLARLYDPTGGRITLDGADLREVADAELRSGVCMV
                     TQEPFLFSGSVADNIALGRPDATREDIVAAAEAVGAHGFISALPEGYDSDVHKRGAGLS
                     AGQRQLVALARVMLSAPRVLILDEATSSMDAPTERAVHTALHRVLAGRTALIIAHSLTT
                     AAIADRVLVLENGVVVEDGPPAVLAAGDGPFAGLYRGWLSATDGRTHHPAHH"
     regulatory      21313..21318
                     /gene="parQ"
                     /note="ORF SriD03.26"
                     /regulatory_class="ribosome_binding_site"
     gene            21313..22969
                     /gene="parQ"
     CDS             21329..22969
                     /codon_start=1
                     /db_xref="GOA:Q2MFN7"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR007867"
                     /db_xref="UniProtKB/TrEMBL:Q2MFN7"
                     /gene="parQ"
                     /note="ORF SriD03.26"
                     /product="putative paromomycin 6'-dehydrogenase"
                     /protein_id="CAF32378.1"
                     /transl_table=11
                     /translation="MEHLRGPSPLANPGARHPELLGPAHRDGFGDEAADRVWDVCVIGS
                     GASGAVAADRLVRQGLDVLMVEEGFRLAGHVDLDEAETLCRQAVARDDEGNWTDEGWPW
                     TTSNLGGGTVFYGGASFRYQPFDFDPGTLIDTGTTEVRWPYTLAELAPYYEVLERRLGV
                     CGGPPAEGSNGARHSRGPAHEPSAAARVLYTAGTSLGYKPFPTPLAINRDPYEGRAGCD
                     RVSLCVSHACPTGAKGDVVAVFLAPLAAHPNFMLRTGVRAVRLEQNRTGEVSALRCLDR
                     VSGQTREVRARAFVLACNAIQTAALLLRSRTAYSPSGVGNHSGLVGRGLCVKLSEYVSG
                     VVQAAPEVLADPDVHKGPFSTVAFLDHYLDEDCPTGVGGLIYESKRDRAPKLVRDALEL
                     RIETILSDHPNLDNRVGLSRYVDEDGLPAIVLDYRTDPRDQARLRYMTGRCERLLRAAG
                     ADGIRHKATGFAQGSSHLHGTCRAGDDPARSVVDGWGRVHSADNVYVVDGSFMPYPGGL
                     NPTLTIQAHALRTSKAVASQLAAPHAAHA"
     regulatory      23001..23007
                     /gene="parN"
                     /note="ORF SriD03.27"
                     /regulatory_class="ribosome_binding_site"
     gene            join(23001..23007,23018..23914)
                     /gene="parN"
     CDS             23018..23914
                     /codon_start=1
                     /db_xref="GOA:Q2MFN6"
                     /db_xref="InterPro:IPR000385"
                     /db_xref="InterPro:IPR007197"
                     /db_xref="UniProtKB/TrEMBL:Q2MFN6"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /function="putative Fe-S oxidoreductase; paromomycin
                     biosynthetic dehydrogenase or epimerase"
                     /gene="parN"
                     /note="ORF SriD03.27"
                     /product="hypothetical protein"
                     /protein_id="CAF32379.1"
                     /transl_table=11
                     /translation="MTTVQWPPRTRRVRAYRNIVIDGACNLRCTYCEVKAIKVDQPATN
                     DSLDRIFAKYEQDNVLFRVESNGEICLYPKILDHLQQRAAEGWQIEVLSNGTRLPRCLE
                     GRENLMWVFSVDGHTARMNEKRGLSQAQVDRIIDTAVELDAELQAVYHDQTIDEVNAFI
                     DTLSARGYKGLLHFMPLLAFKGQPLEVNLRYEDLHPAEFLAPPEYFRRWNHIFETGKRD
                     AVCDQITNGYNYSVADDKIQMVKCDCYSVPKHLYHDFGPIREFDNWPCGTCIANQEFNS
                     SRPRMLAPEGRIPLPLV"
     gene            23911..24606
                     /gene="parP"
     CDS             23911..24606
                     /codon_start=1
                     /db_xref="InterPro:IPR013078"
                     /db_xref="UniProtKB/TrEMBL:Q2MFN5"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /gene="parP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101:phosphoglycerate mutase (Score: 140.3; E-value:
                     9.4e-43)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SriD03.28; putative phosphatase in paromomycin
                     pathway"
                     /product="putative phosphatase"
                     /protein_id="CAF32380.1"
                     /transl_table=11
                     /translation="MTDGTGTPVTRRFLLVRHAQAEVNVLADDDLMEGYDTDADLTPLG
                     REQARALAGHLAGDHASWPGPAGPGGYRLRTSPLRRAVRTAETLAAALGLTAVSDARLA
                     EVRAPRRFPRPLAVREWDALLEQRLRHPEREFAGVESWAAQRARAREFLRECLAGPPAA
                     GFVLVSHAETIQALLMELLDLGDGMLRSARFKVSNTGVFIVDRTLDGTEEPCSSLVVAN
                     SKSHLARTA"
     gene            24603..24875
                     /gene="parX"
     CDS             24603..24875
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFN4"
                     /function="biosynthesis of neomycin"
                     /gene="parX"
                     /note="ORF SriD03.29"
                     /product="hypothetical protein"
                     /protein_id="CAF32381.1"
                     /transl_table=11
                     /translation="MTGAPLAGAAGDRVRLLVVKCLSDETGEDPDAIVARGHLDVGDRD
                     YANIVNRLESYFDCSLDLLAGGNRRLVVDDLCDRLGLLPLEAVHV"
     gene            24868..25971
                     /gene="parF"
     CDS             24868..25971
                     /codon_start=1
                     /db_xref="GOA:Q2MFN3"
                     /db_xref="UniProtKB/TrEMBL:Q2MFN3"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /gene="parF"
                     /note="ORF SriD03.30; putative hexosaminyl- or
                     mannosyltransferase"
                     /product="putative glycosyltransferase III"
                     /protein_id="CAF32382.1"
                     /transl_table=11
                     /translation="MSEPPAASLGAPLDPPGPLRALLEIYDEGFTCDTWGGVETALWHL
                     AEGLREHGVEAEFYRSTEGADLGALAERVVRERVDAVFPLVESPLFVGGASRSERPAAG
                     EGQPEVRELRRRVVRIWHDVSRLSPGLSTPPPCPVHTPGAAAPSGGVCAAAGVFPDGPA
                     REVFLRDLPWTRCFGSRTYIPWAVDHLPPADLRDPFGPVLLQLGKTSVDQARVCLERLT
                     GAGLPVRVVFATWSKEGRAARELVAPYAASGAVEVLDSYDIRTEWKRVYAGARLFVLPS
                     VFHETFNFAAAEALQLGLPVATLGDCGALADFASLRAETVAELMDAVVARGESVRPARR
                     PWTGWREVAHRYATLIAAPRRAPALGV"
     gene            25976..26737
                     /gene="parD"
     CDS             25976..26737
                     /codon_start=1
                     /db_xref="InterPro:IPR003737"
                     /db_xref="UniProtKB/TrEMBL:Q2MFN2"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /function="putative 2'-(or 2'-alternatively
                     3-)N-acetylparomomycin deacetylase (amidase) in paromomycin
                     pathway"
                     /gene="parD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SriD03.31"
                     /product="putative 2-N-acetylhexosamine deacetylase"
                     /protein_id="CAF32383.1"
                     /sec_met_domain="PIG-L (E-value: 1.7e-22, bitscore: 71.9,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGLIEELRDHTTLWISPHPDDVAYSCGGVLAACAGSAPGLLLTV
                     FTRSAWALPKRLRAAGPEVISARRAEEERRYCRARGLARYVPLGFDDASLRGYDDDTEL
                     TADPAADPLRDRIAEAVAEAVAELRPSLVLAPAAVGGHVDHRLVHEAVRRSAGDGVRRL
                     YYEDLPYAAHHPRAATEKALGEEGLSLYAVTGIGSVLEDKVRGMYIYGCQTDDECVQEV
                     TGYAREAAGPGDGTHVERVWAPSPAAAGRAG"
     gene            complement(26770..28683)
                     /gene="parL"
     CDS             complement(26770..28683)
                     /codon_start=1
                     /db_xref="InterPro:IPR000209"
                     /db_xref="UniProtKB/TrEMBL:Q2MFN1"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /function="unknown role in paromomycin production"
                     /gene="parL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NeoL"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SriD03.32"
                     /product="hypothetical protein"
                     /protein_id="CAF32384.1"
                     /sec_met_domain="NeoL (E-value: 1.6e-205, bitscore: 674.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASAVRLGSAEARYACACSIEQLLADTAACPTAPESARALLDEVR
                     QACQDLARAVAAGPGGQFAPPAPGPGFLERAMARTAAYTAGLWRTGAARGDTAAEALLR
                     HATDWKTPECYAYDLADVGLVHGQAAAWLAATEEPVPVFVVGIRTGGSYLAPLWAAAVA
                     AAGRTAAPWTSLRPLRTGGRISLVPAETGRLPATLPPGTVVVAVDDQPDTGGTARAVRD
                     ALARRYPEARDVVCASPGRTYAVDGAGIRPLTRTSAVREDAGRLWQLLAPADADRLTDR
                     ARSGGAVPADATVYRVTPFRGPFLAAYGPRATATDAPGAGTSPAGPADSAGTRPAGPAD
                     ATSTPPATGALRISPRNTPFSLVADEPATGIPGAPDARPRAYHFRFIGTGPHGAQGAEA
                     VEALGEFLPPVRHHLDGYLVTGHEDGLRPLATELPRMTGRHRRQALEAVARYWHALDHL
                     GGLGPVDPTVTYAPRERLATALERLRDRLARPLPVDGAWLDRHLPRRAAFGGTRARVFR
                     TSLPYSHQSWHWQVGAPPAPGAPPVVRRFGLDWIWGGTGPLEAEISSFVVEHRLDPADL
                     ATLRTAVGDDRAFDAALELAGDALWWNVKSWLRRCPAPAPDTARRIADDLGELARYVTG
                     LR"
     regulatory      28985..28994
                     /gene="parB"
                     /note="ORF SriD03.33"
                     /regulatory_class="ribosome_binding_site"
     gene            28985..30254
                     /gene="parB"
     CDS             29001..30254
                     /NRPS_PKS="Domain: Aminotran_3 (25-317). E-value: 1.3e-14.
                     Score: 45.8. Matches aSDomain:
                     nrpspksdomains_parB_Aminotran_3.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MFN0"
                     /db_xref="InterPro:IPR005814"
                     /db_xref="UniProtKB/TrEMBL:Q2MFN0"
                     /gene="parB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 244.1;
                     E-value: 4.2e-74)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SriD03.33; pyridoxalphosphate-dependent
                     aminotransferases class III"
                     /product="putative paromomycin 6'-aminotransferase"
                     /protein_id="CAF32385.1"
                     /sec_met_domain="Aminotran_3 (E-value: 3.7e-17, bitscore:
                     53.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQNFATLAEIPTCPRNAEGNPRVFVSASGAYVTDDAGKRWIDFD
                     NTRGSVLLGHGDPEVAEAVGRAATGALGTATGWSPLLDTVTSRLLELCGGEVVGLFRTG
                     TSAVRAAVLAVREAVGAPLVLSSGYHGYDPMWYPAKAPFEPNADGIVDFFFDLDVLAGL
                     LRDGRERVAAVVVSPDHMHLSPRWYERARALLAEAAVPLIVDEVKVGLRYGPGLSTAGL
                     LDADVWVTAKGVANGFPTAAVGGSRTLLKPLREVSYTSFFEPTVLAAAERTLARVATGE
                     PQRTVRETGDLFVEHARSALAAASLPLEVAGNGTFFQFVPATREVKKAFYKATEEEGLL
                     FYRNDNQAVSAAFGPDVLDDARARFSRVCDRLAPFAAAGPVGEEARYQAAWSVMDGLRE
                     AERDARETREWVDRFLDD"
     aSDomain        29076..29951
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_parB_Aminotran_3.1"
                     /evalue="1.30E-14"
                     /label="parB_Aminotran_3.1"
                     /locus_tag="parB"
                     /protein_end="317"
                     /protein_start="25"
                     /score="45.8"
                     /tool="antismash"
                     /translation="VSASGAYVTDDAGKRWIDFDNTRGSVLLGHGDPEVAEAVGRAATG
                     ALGTATGWSPLLDTVTSRLLELCGGEVVGLFRTGTSAVRAAVLAVREAVGAPLVLSSGY
                     HGYDPMWYPAKAPFEPNADGIVDFFFDLDVLAGLLRDGRERVAAVVVSPDHMHLSPRWY
                     ERARALLAEAAVPLIVDEVKVGLRYGPGLSTAGLLDADVWVTAKGVANGFPTAAVGGSR
                     TLLKPLREVSYTSFFEPTVLAAAERTLARVATGEPQRTVRETGDLFVEHARSALAAASL
                     PLEVAGNGTFF"
     regulatory      30285..30294
                     /gene="parA"
                     /note="ORF SriD03.34"
                     /regulatory_class="ribosome_binding_site"
     gene            30285..34213
                     /gene="parA"
     CDS             30305..34213
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFM9"
                     /function="biosynthesis of neomycin-related
                     aminoglycosides"
                     /gene="parA"
                     /note="ORF SriD03.34"
                     /product="putative paromomycin production protein"
                     /protein_id="CAF32386.2"
                     /transl_table=11
                     /translation="MDRPSNPRPADPESAYGAKCARLLELSTHPRFTSVALPVFPLADG
                     TAREFLKSVRDAGGQTGGAAPQNAAGDTGETLPQNAAGGTGETLPQDTAEELVTGYARF
                     LRRQWPGLADEIARTCGPAPWIVRSSGAEDQEDNINAGGYDSLVCAGPEELPAVVAAVV
                     FSGYGEHAVAQQRLADPDFRPAPIAAFVQPLIDASAVSGPPPAPQETPRLGRPETDRTA
                     RLLAALHDHFGMARLDCEWVLETDAGTVSVTSLTEYEEGSGVVGQLSLGFGFASAQRLD
                     GTDNSVVWLPGDGRTPLWRGEVLRSVQVRAAHLVQVRPAVAFDPAPTVQVLTDEDREVW
                     EDAHTGRPVDLLVPPRQVAATAFLAAARLDDAWTQYLRLDEGQRAATGHVLVERGSPAE
                     HAAVMFRQYGVAVLRCRAEDVPESASYVLADPWAERCYFGTGHPPRARTVPRRVAAVPS
                     GCRLLFDERACGRAAEALVDGRRPGPETMPGYEELRTAAHLSPTARDRLVARSFLPDPE
                     CHHRDGTAVTSPAFVAQAAAAALGLGADPARLLEAVPQEAAGYVRGLVAARSAGHVAAV
                     LPRCARLMGPQRLAAATGGPDVRLAAALARFDGRDALSDTVLRRLLPPVLALADADGGA
                     DAALDPLLAVESLTDAMDALDIHADHERDDILVRLLDALPLEDPEAAGELCRLARRSSL
                     PPGETSRLVATAAADPDFAARHLALERCRVALSAADPAAAPRRARELAAAYRAFARGPL
                     LDGDGRVLLNLVRCDLIETYDAALKDLLLKLVDRPGPVLHQGYLGVMLGWLELAEAFGP
                     TAREARAVEVFRTWIEEWRAGPPAEDHTIEEGASWQRLLESAADATVPPPAPANAHRLH
                     NALHQWLLATTDRYPAERAPSGVAGLHAVADRFCRGGNKLLRLTRDSFELDVPLSLHKA
                     SLLFTPGRIEAEWSEQPDVTEEETGRIAAFEVLLARFGDWFPGVELRSERLLAAGTWTL
                     RIEARPTGQGHFDLPRMRLVLGLLRTLFDGSYDFSYVPVKEVTHLSDAFASARWAAVFA
                     SLVEYRTHYDDSAQYETLETLPLALSMGMLCTDTWTRETVLRLADESPDAAVSQLDALI
                     EELREETAPAAWTLLFHRTQQTALFLAAHHPREALVALAARPTAAWANILATAVLPRAD
                     LREALRAALRQDGPDGALTTLVLRHAPHLVVTAADAAELARAALRAPKAHRRRKQYLAH
                     RHAVALEAADLLGPLVEDLEVVPYGYDADAEAALERAVAAAGGRLRADIRSKIDETHPV
                     FLGGPSAAVPAVPSGAAR"
     gene            complement(34259..35626)
                     /gene="parK"
     CDS             complement(34259..35626)
                     /codon_start=1
                     /db_xref="GOA:Q2MFM8"
                     /db_xref="HSSP:P05187"
                     /db_xref="InterPro:IPR001952"
                     /db_xref="UniProtKB/TrEMBL:Q2MFM8"
                     /function="secreted protein"
                     /gene="parK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) strK1"
                     /gene_kind="biosynthetic-additional"
                     /product="extracellular aminoglycoside phosphate
                     phosphatase"
                     /protein_id="CAG44621.1"
                     /sec_met_domain="strK1 (E-value: 3.5e-257, bitscore: 844.7,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSTSLPPQVFRRRLAWSAAALAVAVTATTVVTATADAGAGHRPR
                     TAKNVILLIGDGMGDSEITLARDYTVGAGGRLHMDGFPQTGTYTTYSVDSHGRPDYVTD
                     SAASATAWSTGHKTVNYRISKTPGTDRPMPTILELARRQGLATGSVTTAELTDATPAAM
                     AAHVGDRDCQGPADMEGCPRDTIGRGGLGSIAEQSVRLRPDVLLGGGRQRFDQKITEGP
                     YQGLTVAQQAEKLGYRIVSDARGLRAAGPERPVLGLFAPGAVPVEWTGRPAARGGTEAQ
                     RCVTANPRRPAGTPTLEAQTRKAVELLEAKARTGGTGKGFFLQVEGASIDKQNHEADPC
                     GQIGETAAFDRAVKVARDYAERHPDTLVITTADHGHSSQIVPVDAEPMGLSATLVTDEG
                     GRIKVSYATTTTPEDGQEHTGTQVRIAAQGPFAERVRGVTDQTELFTTITRALGLR"
     gene            35834..36325
                     /gene="parI"
     CDS             35834..36325
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFM7"
                     /function="possible regulatory protein"
                     /gene="parI"
                     /product="ParI"
                     /protein_id="CAG44622.1"
                     /transl_table=11
                     /translation="MSDRTSATDQEGRPLLRAFGQRLNELIAALHPDERKRPGYARLAK
                     EIRETTGGAISGTYLWELATGKKRNVTLEQLDVLAEYFGVPPEYFLSDDVAERVNSQLR
                     LAVALRDTRVRNLALRAEGLSPAALDALLTIVDEARKVQNLAPPEAGGDGTQEPPAAAP
                     "
     gene            36406..37194
                     /gene="parR (aphA)"
     CDS             36406..37194
                     /codon_start=1
                     /db_xref="GOA:Q2MFM6"
                     /db_xref="InterPro:IPR002575"
                     /db_xref="InterPro:IPR008266"
                     /db_xref="InterPro:IPR012149"
                     /db_xref="UniProtKB/TrEMBL:Q2MFM6"
                     /function="paromomycin resistance"
                     /gene="parR__aphA_"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="resistance (resist) APH3 (Score: 286.9;
                     E-value: 9.1e-88)"
                     /gene_kind="other"
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="CAG44623.1"
                     /sec_met_domain="APH (E-value: 8.7e-35, bitscore: 112.1,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEEVLKLYPRHTWTPVTDGDSGAFVHHLTGPSELYAKLVPARPD
                     TGLDLKAEADRLEWLAGQGVPVSRVVDFGSGDAASWLITEAVPGVSAAEEWPSAQRAEV
                     AEVMADVARQLHGLPVADCPFDASLDVMIPQALHHLEAGLVDMDDLEEERAGWSEGRLR
                     AELEGTRPPQEDLVVCHGDLCPNNVLLDPETRRLTGVIDVGRLGRADRHADLALAMREL
                     SREEDPWFGPHCVERFVERYGAERVDATKTAYYQLLDEFF"
     gene            complement(37279..37968)
                     /gene="parY"
     CDS             complement(37279..37968)
                     /codon_start=1
                     /db_xref="InterPro:IPR006311"
                     /db_xref="InterPro:IPR009327"
                     /db_xref="UniProtKB/TrEMBL:Q2MFM5"
                     /gene="parY"
                     /product="hypothetical protein ParY"
                     /protein_id="CAG44624.1"
                     /transl_table=11
                     /translation="METDECGRSCPFHQGGEQSPAPRGRENPSPRGGLSRRAALGLTAA
                     GVLGVTATACGGSGAAKAPERAAATSGAPATAGARGKQPETARLLGMRAHPEGGWYKET
                     WRSGKTLRVEEYAGNRPTASAIYFLLSAGEESRWHTVRSSELWFWHRGGPLRFQLGGTG
                     ERPAARPTDVLMGPDLAGGQRPQVLIPAGTWQRARPVSDEEVLVSCVVSPGFQFEDFHL
                     LPEAPAR"
     gene            complement(37996..39198)
                     /gene="parG"
     CDS             complement(37996..39198)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFM4"
                     /function="possible regulatory protein"
                     /gene="parG"
                     /product="ParG"
                     /protein_id="CAG44625.1"
                     /transl_table=11
                     /translation="MTDRGPHGLFVQLEWLGLALMWVVTLLRAPVAVRTPQQRPLWLAV
                     GLASVAMTLQLPQVSSVATAVLDPHTVFLAKEIVGLLAATAVFEFISAIVGLRRTQLAI
                     LAAAVLTLAALVTLCVLSPPHTRHVVPSGPGQEASPDTYYWVVLLGYHLVANTACVAAC
                     WACGRQVKNTPTRAGLLLFGTGIALSAVLMALSLVHVLSRDATIPHLFPAISGAEAAFM
                     AAGAALPLLRRPWRTARDMAVMYRLHPLWRTLVRVTPDVTLTDPRSRAVDLLSAVRHSD
                     LRLYRRAIEIRDGLLALEDYSPEGTLARAREHVRAARVADASVEAAVTGCWASAAVANK
                     RSGAATSGRPSGLPQSGGGDMAEELDFLLQLARFFRSPLAASFLSAEEQRHRAAPTGQA
                     S"
     gene            complement(39191..39745)
                     /gene="parH"
     CDS             complement(39191..39745)
                     /codon_start=1
                     /db_xref="InterPro:IPR006025"
                     /db_xref="UniProtKB/TrEMBL:Q2MFM3"
                     /function="possible regulatory protein"
                     /gene="parH"
                     /product="ParH"
                     /protein_id="CAG44626.1"
                     /transl_table=11
                     /translation="MRCPSQKKWQFSHMLYGYSTLRRRCRAKLTDITLPTPFSVEEFCR
                     SISEQRQRPLHLHALPTHVAKMAACGLWLATDTDDHIFFEARTAPLHQEHIVLHEIGHL
                     LFDHQMLADGNSGGISSVLADLSPRLIQRMLARTNYSTRQEQEAEMLASLIRTHATGPG
                     RGPQRCATTDRADRALGITHD"
     gene            complement(40697..40927)
                     /gene="SriL03.14c"
     CDS             complement(40697..40927)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFM2"
                     /gene="SriL03.14c"
                     /note="fragmentary ORF; outside paromomycin cluster"
                     /product="NDP-hexose synthase (fragment)"
                     /protein_id="CAG44627.1"
                     /transl_table=11
                     /translation="MGPCRVGGCIPRPRGGARPCGSRAVVGAALVVADAVSREFGVSKA
                     RQALGWRGLSAGGGVCGPLGTVRRPRSPARV"
     gene            41695..44022
                     /gene="SriL03.13"
     CDS             41695..44022
                     /codon_start=1
                     /db_xref="GOA:Q2MFM1"
                     /db_xref="HSSP:Q6TMG6"
                     /db_xref="InterPro:IPR001223"
                     /db_xref="InterPro:IPR001579"
                     /db_xref="InterPro:IPR001919"
                     /db_xref="InterPro:IPR003961"
                     /db_xref="InterPro:IPR008957"
                     /db_xref="InterPro:IPR011583"
                     /db_xref="InterPro:IPR012291"
                     /db_xref="UniProtKB/TrEMBL:Q2MFM1"
                     /function="secreted protein"
                     /gene="SriL03.13"
                     /product="chitinase"
                     /protein_id="CAG44628.1"
                     /transl_table=11
                     /translation="MKDRRRFRSRLRGSAAALLTTLILSVAAVLTGPAAPAQAAGTLTA
                     AFSTQDNGPWWKGTYVVRNSGSAAVTGWTLEFDLPAGVTVSGHYYGDATVNGRHVTVKN
                     AHYNATVPAGGSTEPFSYWFVANGPVGTPTACTVNGDKCDGSPDVPPSAPGTPQVTGTT
                     ARSVALSWPAASPGDHPVTSYEVLSEGRPVATATGTTATVTGLTPATRYTFTVRAKDRR
                     GNTGPPSAPVTADTVDPASDPVPPTAPRALRSTAVTASSVSLAWDRATDNVGVVAYDVY
                     RGADLVTTVPGSTTAATVDGLTPATTYRFSVTARDAAENASPASDALTVTTDDVAGPGK
                     YLKVGYFAQWGIYGRQYFVKNLDTSGAAADLDVVNYAFANIDPKNLTCLAGVTKGVSGN
                     PQDPDEGTGAGDADADYGRAFPAAQSVDGVADDGWGKLRGNLNQLKKLKAKHPHLKVVM
                     SLGGWTYSKFFSDAAATDASRKKFAASCIDIWIKGNLPVYNGAGGPGTGAGIFDGIDLD
                     WEWPGAEGHPGNHYSPDDKANLALLIKEFRRQLDALGGPHKLLTAFTPADPVKIQQGWD
                     LASIFTSLDYANVQGYDFHGSGSDNSWEPKRTGHQANLYRDTQDPYDFHFSVENAVKAY
                     TDAGVSPRKLTIGFPFYGRGWKTVADGGAHGEWQSADGAAPGQFPEEAGIRGYQNMLTN
                     VPDMTVHHDEQSISTYGYTGANGQWWSFDDTWSIGKKTDWVKSKGLLGAMIWEMSGDTP
                     TGTLMKAIKNGLAGRPGAAPTG"
     gene            complement(44247..45101)
                     /gene="SriL03.12c"
     CDS             complement(44247..45101)
                     /codon_start=1
                     /db_xref="InterPro:IPR013120"
                     /db_xref="UniProtKB/TrEMBL:Q2MFM0"
                     /function="nucleosidediphosphate-sugar oxidoreductase"
                     /gene="SriL03.12c"
                     /gene_functions="other (smcogs) SMCOG1199:NmrA family
                     protein (Score: 198.5; E-value: 2.7e-60)"
                     /gene_kind="other"
                     /product="SriL03.12c"
                     /protein_id="CAG44629.1"
                     /transl_table=11
                     /translation="MIVVTGATGGLGGATVEHLLQRVPADQIGVSVREVAKAQHLADRG
                     VRVRQGSYEEPAVLRGSFAGADQVLLVSGNDPTADLVHLHRNAIDAAVAAGARRILYTS
                     QHGAIPGNPYPASDIHRATEAILADCGVAWTALRNGAYGPLDQVLGPWRRTGEIAQPAD
                     GPVPYTDRDDVAEAVAVILTGDRSFEGPVTLTAPTAVTFDDLATIASDLTGRTVKRTVL
                     DDEQWVADQLMTGVPERAARFMLTWYQASRAGYFAEADPLLAQLLGREPRSAADRLAAD
                     IAA"
     gene            45215..45844
                     /gene="SriL03.11"
     CDS             45215..45844
                     /codon_start=1
                     /db_xref="GOA:Q2MFL9"
                     /db_xref="InterPro:IPR000408"
                     /db_xref="InterPro:IPR001647"
                     /db_xref="InterPro:IPR012287"
                     /db_xref="UniProtKB/TrEMBL:Q2MFL9"
                     /function="putative transcriptional regulator (tetR
                     family)"
                     /gene="SriL03.11"
                     /product="SriL03.11"
                     /protein_id="CAG44630.1"
                     /transl_table=11
                     /translation="MGQIESAGAGASGGAAPSASRLRADARRNSEQIRAAAIGAFQGRG
                     LTVPLEDVAKAAGVSKATIFNRFGGRIGLIEAVIEEVVATELFAVIDRARTIADAGERT
                     AYYLTALRDLQYRQPAVNDVLLQTYPHSQQLMEICRAGSEANTEIVAAARAGGAVRPEF
                     TAGDLHALVVDTALALKHGQRPPRDEYDRRTTYLLDGIRGPRPTLG"
     gene            complement(45997..46875)
                     /gene="SriL03.10c"
     CDS             complement(45997..46875)
                     /codon_start=1
                     /db_xref="GOA:Q2MFL8"
                     /db_xref="InterPro:IPR001387"
                     /db_xref="UniProtKB/TrEMBL:Q2MFL8"
                     /function="putative transcriptional regulator"
                     /gene="SriL03.10c"
                     /product="SriL03.10c"
                     /protein_id="CAG44631.1"
                     /transl_table=11
                     /translation="MASVNREIADFLRRSRAQCDPERAGLPPDGRVRRVPGLRREEVAL
                     LAGVSADYYARLEQGRPINPSPAVVEAIGHALRLDEAGLAHLKNLVGVTATRPPARTPG
                     VQRLRPGLHRLLDSLDHALPALILGRRSAVLGANRMARALFADFDAMPATERNYTRWLF
                     LDHGARDLFVDWEVQARAAVENLRLDAARASERQATEALVAELRGLSDDFDRWWQQHRV
                     HQRTHGSKRLRHPLVGELTVEYETLALPGDSETTLFLYTAEPESASAQALSLLASWTLA
                     APPTFPDRSRD"
     gene            47072..47929
                     /gene="SriL03.9"
     CDS             47072..47929
                     /NRPS_PKS="Domain: PKS_KR (8-168). E-value: 1.1e-16. Score:
                     53.2. Matches aSDomain: nrpspksdomains_SriL03.9_PKS_KR.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MFL7"
                     /db_xref="InterPro:IPR002198"
                     /db_xref="InterPro:IPR002347"
                     /db_xref="UniProtKB/TrEMBL:Q2MFL7"
                     /function="oxidoreductase"
                     /gene="SriL03.9"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     206.9; E-value: 6e-63)"
                     /gene_kind="biosynthetic-additional"
                     /product="SriL03.9"
                     /protein_id="CAG44632.1"
                     /sec_met_domain="adh_short (E-value: 1.7e-34, bitscore:
                     110.7, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.8e-08, bitscore:
                     24.5, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATTVPATWFVTGASRGLGLELVRQLLAQGDNVAATTRSPERLT
                     TALGGAADTGRLLALNVDLTDEAQVQHAVDRTTERFGRLDVVVNNAGYGYLAAVEETSA
                     KDVRDMLDVQVVGVWNVLRAALPVLREQRAGRVINISSILGLTTMPGWALYCAGKFALE
                     GLSEALAAEVADFGIKVTVVEPGYFRTSFLTTESLALPAETSEHYPAVRAMVDDHLKLQ
                     GRQLGDPVKGAAAIIERAGLDDGPLRQLLGSDAHAYATAKVDALRADLDATAASAAITD
                     FPEA"
     CDS_motif       47096..47164
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SriL03.9_0001"
                     /evalue="4.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="SriL03.9"
                     /protein_end="31"
                     /protein_start="8"
                     /score="16.1"
                     /tool="antismash"
                     /translation="TWFVTGASRGLGLELVRQLLAQG"
     aSDomain        47096..47575
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SriL03.9_PKS_KR.1"
                     /evalue="1.10E-16"
                     /label="SriL03.9_PKS_KR.1"
                     /locus_tag="SriL03.9"
                     /protein_end="168"
                     /protein_start="8"
                     /score="53.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TWFVTGASRGLGLELVRQLLAQGDNVAATTRSPERLTTALGGAAD
                     TGRLLALNVDLTDEAQVQHAVDRTTERFGRLDVVVNNAGYGYLAAVEETSAKDVRDMLD
                     VQVVGVWNVLRAALPVLREQRAGRVINISSILGLTTMPGWALYCAGKFALEGLSEA"
     gene            48045..>48169
                     /gene="SriL03.8"
     CDS             48045..>48169
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MFL6"
                     /function="conserved hypothetical protein (partial)"
                     /gene="SriL03.8"
                     /product="SriL03.8"
                     /protein_id="CAG44633.1"
                     /transl_table=11
                     /translation="MTATPGALHTVLGAGPTGTSGVLELARRGHAVRLVDRSDSG"
ORIGIN
        1 tgccgggcca gctcgtaccc ggtcaccagc caagcctgtt caccggagtt ggtgttgacc
       61 cgggccacgg gacagcggcc gcgcagctcg tcgagttcgg gggcgagccg gtcgccccgg
      121 gtgctgaagg ggtagcgcgg gaggggctcc tcgtgggctg cctggccgga cgcgggcgct
      181 tgcggtggtg tggacacgtg ggatgagcct ctttctcgtt gctgtgggga gggcgcggac
      241 aaggcccgct cgggccacgg ggcccgagcg ggccggtctc accagcgcac agggagccgg
      301 gccggtgcgc gcagcggggt ggactggtcc cagtcgatct tctcggccgg gacggcgagt
      361 tcgaggtccg ggagccgttc cagcagcacc tggatcgcga tggtcagctg catacgggtc
      421 aggttcgcgc cggtgcacgc gtgcgggccg tgcccgaagg cgatgtgcgc gttgggggtc
      481 cgggccaggt cgaggcggtc gggctcgacg aacgccgccg ggtcgcggtt ggcggacgcc
      541 ggtacgggca cgaccgcgtc cccggcccgg atgtgctgcc cgtgcagggt gaagtcctcg
      601 gtcgccacga ggatgttgat ggcgttcatc agcgggacgt agcgcagcag ttcctccacc
      661 gcggtgggga tccgctcggg cgccgcacgc agggtgcgca gttgctcggg gtgggtgagc
      721 agggcgagca gggcgttgcc cgtgtgctgg atgttggtct tgtagccggc catgagcatg
      781 gtgacgacaa agctcaccac gtcgtcccgg gtgatctcgc tgtccggccg gcgggccagg
      841 gccagcagga gccggatgta gtcctcgccg tcgccgtcgc gttccttgcg ggcgatgagg
      901 tcgccggcgt agtcctgcag ggcgtacagg gcggcgagca cctcctccat cgtcagcccg
      961 gcggcgccca ggagtgcgag ggtgtgcggc aggtagatct cccggtcctc gtacggcagg
     1021 ccgacggtct cgcacagcac ccgcaggggc agcggttcgg cgtaggaggc gacgaggtcc
     1081 gcggggccgc cgtccgaccc ggccaccatc gtgtcgacga ggtccccggc catcgcacgg
     1141 atccggggct ccatgaagga cagctgccgt cggccgaaca tcggcaggac ggtgcgccgt
     1201 acgcgctcgt ggtgcgcgcc cgtcatctcc aggaaggtcg gcaggcacgg cggcggggcg
     1261 tcggccccct cgcggggcgg ccaggccgac agcaggggcc gcacgagccg cgggtcggcg
     1321 aacgcggcgc gcgcgtcctc gtagcggctg atgagccagc ccgtctcgcc gttcgggagc
     1381 tgggccttga cgacgggtgc ttcggtacgc aggcgggcgt acgcgcacgg cggtccgggg
     1441 gtgccggggg cggtctccgg gacggggatg agggcttcgg gggcggcggc gtccgggacg
     1501 gcggcttcgg ggcggctcat cggctgcgct ccgtgcgggc tgcggctgcg gtcccggata
     1561 tcggctcggc ggcgggtatc ggctcggtcc cggatatcgg cccggcggca gaaatcggtt
     1621 cggtcccgga tatcggctcg gcggcagaaa tcggttcggt cccggatatc ggttcggtcc
     1681 cggacaccgg ctcgtcctcc ggtattcgct cggcctcgga ttcgggcccg gggccggccg
     1741 ccgggcgcgt gaggtagccg gaggtgaaga agtactccag gtagcggtcc agcagagcgg
     1801 agtcgaccgg cgggcagtgc agcccgctgc cggccagcgc ctcctcggcg ttgcgccgcc
     1861 ccaggaccgg gaaggtgccc ttgaggtaca tctccttgac ggacatgtcg gcggtgcggc
     1921 tgcggtccac gcacagggac acgaacggag ccgtggcgct cgtcgggttc tcggcgacgt
     1981 gccggacgag ctcgccgacc cacgcgtcgt acggcagggt gcgcagggtg aagcccgccg
     2041 cgcgcatccg gtcgaggacg tccgacagca tcgccgggcg cgggttggtc aggtggtaga
     2101 cccggccgtc ggccggccgg tgcgtggcga tgtgcaccag ggactcggcg aggtggtcga
     2161 cgggtacgaa gtccatcggc agcttgatgt cgggggccac tcccgtgtcg gcgatcatct
     2221 tgaacagcga gcagatggcc gtctcggtgt tgcacgcgcc gtgcgtccgg tcgcccgtga
     2281 cctcgtacgg ccggtacacg gccaccggca ggccctgcgc ggccgcctgc cgcagcaccc
     2341 cttcggcgac ccacttgctc tccgcgtacc ccatggtcag cccgtcggcg tgggccggcg
     2401 gcagatcttc gtccacctcg cgcaccccgg cggtgccgaa gcccgcgacg actgcgacgg
     2461 tggacacgaa gtgcaccggc acccggcggc gcgcggcgat ccggacgacc tcgcgggttc
     2521 cgtcgacgtt cgccgggcgc aactgctggt aggggtagag gaagttgacc cgggcaccgt
     2581 tgtgcacgat caggtccagg cgctgggcca gtgcgtcggc gcgctcgtgg tcgagcccca
     2641 ggcgcggctg ggtcaggtcc ccggggaagc actccacgcg ctgccagtcg gcctcgtcga
     2701 ggtgcagccc gtagcgggtg agggcggtgc ggacccgctg ccgggcgtgg gcggggctcg
     2761 tcgcccgtac ggggcagtgg acgcgggcgg ccgtcgcgtg cagcagacgg tgcagcagga
     2821 atccgccgac gaagccggaa gcgcccgtga gcaggacgtc ctcggggtcg tgcgggttcg
     2881 gcgccgggcc ttcggcgggc gggagggcga agccgagtcc ggtctccgcg gcgaagtcga
     2941 cggccggttc ctggccgccg gccggtccgc cggtgccgcc gcggactccg cgtacggcgg
     3001 cggtgaagct ttcgagggtg ggcgcggcca gcagcgccct gatgagggtg gagcccaggg
     3061 ccgcgtcgag gccgagtacg gcgagggtgc gggtgacggt ctccgaggcg agcagggagt
     3121 cgccgccgag gaggaagaag tcgtcccggg gcgtgggccg gacacgcagc acctggtgcc
     3181 acacttccga gaggagaccg gacaggccgt cggtggcctc cggctcgtcc gggcgccgcg
     3241 cggcctccgc ggtgtcttcg gggccgggcg gtggcgcggt cggcttcaga cggctgcggt
     3301 cgatcttgcc gccgctggtg accgggaagc ggtccagggg tatcagggcc gggacggcct
     3361 gcgggggcag ccacttggcg cagtacgcgc gcaggtcggc cagcggcagc gggcggccgg
     3421 ggacggtggc cgtgacgtag gcggtcaggg agtgcccgtc gacctcgacg gccgcttcgc
     3481 cgacctcggg gtgggcccgt aagcgggtct ccacctcgtc cagctcgatg cgggcgccgc
     3541 gcagcttgac ctggcggtcg agccgtccgc ggtactccag cagcccgtcg gcgtgccgta
     3601 cggcccggtc gccggtccgg tacagcggtc cgtccggctc gaccgcgggc agcgtcacga
     3661 accgctcggc ggtcagctgc gggtcgccga ggtagcccag cgccagcccg tccccgccga
     3721 cgtacagctc cccttcctcg cccggccgcg cgggcgagcc gtcggcccgc aggacgtggc
     3781 aggtggaagc gccgaagggg cgtcccaggg ggacgtgtgc ggcgtcctcg gggagggggg
     3841 tgagcacatg ggcggtggag accacggcgt tctcggtcgg gccgtagaag ttgaccaccg
     3901 tggtgcgggg gcaggccgcg aggacggcgt tcgccaggcg cgggtccatc gcctccccgc
     3961 ccgcggagac gaaccgcagg ccggccagcg cctcggggcg ggtccgggcg acgaggtgga
     4021 agacgctcgt cgtcaggtac gccacggtga cgccgcccgc gcggagcagc cgttccaggg
     4081 cggtgggcga gagcagttcc tcgcggtcgg cgacgaccag gcaggcgccg gtcagcagcg
     4141 cgccccagat ctcgatggtc gaggcgtcgg aggacaggct gtaggcgtgc agcactccgt
     4201 cgcccggtcc gggtggcgtg aggccggggt cggacagcac gaggcggacc acgccccggt
     4261 gggacagcgc tacgggcttg ggccggccgg tcgtgccgga agtgaaggcg acgtaggcgc
     4321 agtcggcggc ggagccggtg gcccggtcgg gggcggggcc gctcgcgcgc tcgggggcgg
     4381 gccggccgag ggagccgacc tcgactgaca cgcgtagacc ccgcacccgg cgcgtgctgc
     4441 ccggcagggt gaccgcggcg ctgatgcccg cgtcctcggc catggcccgc agccgggccg
     4501 gcggcagttc ctcgtcgagc ggtacgtacg cgcagccggc cttgaggatg cccagcagcg
     4561 ccaccagcgc ctccagggaa cggctgccgc acacgccgat caggtcaccc ggccggaccc
     4621 cgccggcagc cagccggtcc gccaacgcgt cggcgtgggc gtcgagttgg ccgtaggtca
     4681 gggtgcggtc cccgtgccgg gccgccgggg cctgcggcag cgccgcggcc tgtgcctcga
     4741 acagctccgg gatgcggctg tcccgtgggt agccgggcgc cggcgtgcgg gcacccggga
     4801 cctggggccg cttggataac gggcgtgaag aaacgtacgt gtcggtcatg tgatctctct
     4861 cgctccaacg gcttgcgtgc ggtacggcgg tgcgcgggca ggtccgctca gcgcgggacg
     4921 gtttcctccc cggcgccccc ttcggcgaag tcggccgcga aggccgcgaa gtcggcactg
     4981 cgccagtgct gcgggcgcat ccggaaggcg atgtcctccg tgagctggcc ggaggtcgcc
     5041 gccaggtagc cgcgggcctc ctcggcgtcc aggtagcggt gggccagggc ctcgcgcagc
     5101 gccgggtcca gcgggtcgtc gatcgcggtg acgggccctt cgacgctgac gtagcggtac
     5161 ggccgtccct cgtcctgcgc gcagaggctg aaccgcccgg cggcacgcag gagctgggcc
     5221 ttgacggtct ggcggccggt ctcgacgacg acctcgcccc cgggttcgta gctgtaccag
     5281 accggcacga tcagaggccc ccggtcaccg cctctggagt ccgtcacacc caggaccccc
     5341 acgcgcggtt cggcgaggaa gcgttcacgg tcggggcgcg acatggcggg cagcatggga
     5401 ggactcctgt ctcggcactg cggctgaaga ggtggtgttg cggcaagctc gccgcgataa
     5461 caatcttgag aacgaggaga tcactcccct gccgaatgac gggcaaacat accctttagg
     5521 cggttttgag ccgctggcag cacggcgcga cgcgggcgcc ccggggagcc tcccccgccg
     5581 aaaaccgttg cgcccgcgcc tgcttgacgc ccccgtcccg cgcgacagct gggcttaccg
     5641 gccgtaacgc gcggacaccg tacggagtcg acccggcacg gccccacgcc cacgcctccc
     5701 cggcagaccg acttgaaaga gacgcacgtg cggcggcctg ccgcagcggg cgggcggcgg
     5761 atcttccccg cgcgtacgag gtgcggggga acaggtggcc gaccaggccc gatgaaacgc
     5821 ctcccggccc gtggcgacaa gttgcgcggc gggccccggg gcatcgcata ctgcctccgt
     5881 ggatacggat accgagtcgc cggccacccc accggccccc accaccgcga gcggccccgc
     5941 agaccaggaa cagttcgacg agcgggagtc cgccgccgac gcacggcagt gcctcgccga
     6001 cgctcgcgag gacgtgaccg gcgaacgcga ccggctcacc ggcccccggg agtccgtcgc
     6061 cgacccccgt cagcacttcc tcgacgcgcg ggagatccac gcggaccggc tcagccggct
     6121 cacggaaatc accgtgccca cccgccggaa gcggtccttc gaggcgatcg gccgcgcgcg
     6181 ggtcctgctc gcttccagcc aggtgcggct ggaccgcacc gaagcaactc tgagccacac
     6241 ggaatccggt gacgcgcgcg agcggcgcag cgccgagcag gagatcgccg cctccatccg
     6301 gcgggccttc ggcgacgaaa tgtcgcaaca ggccgccctg gagagcctgg tggggcagtt
     6361 gcaggcacgg ttccgcacgg cggcggccgc actggccgag gcccaggacc agctggcgca
     6421 ccatcacgaa cgcctggccg ccgacggcca cccggacgcg gacgaccacc gtgtccgcgc
     6481 cgaacgggcc cgccgggccg cccggcgggt ccgcgcggcc gtccagacga gggccgcgga
     6541 gccgacgacc gcaccaccga aggacgaccg gtcggccgag tcgccggccc tcgcaccgga
     6601 cacgggcacg taagggcgaa accggcgcct cacccctcgg acccaactcc acagttagaa
     6661 gctctcacca aactgttgcc ccctcacccc ttttggttat agcttataac tacagcgcga
     6721 gcttataacc cagtggacgt gcggcgcccc gcacgccccc gcaccgcgct ccaccggacc
     6781 gagggacccg catgaccacc acacttgagc cacccggcgc ccgcacccgc aaccgcgccc
     6841 gcacccgcac ccgcacccgc acccgcaccc gcacagatcg cgtgccgctg tcgctgaccg
     6901 tctcctcctg ggcggtcccc gtcatggtcg tcggccagtt cgccctgctg tcgggcatcc
     6961 cggtcgccat cgcgttggcc ggcgctctcc ggcaggtgcc ggaccgggca gtccgctgga
     7021 cagcggccct gctcgccgtc acgtacgccg tcccactcac cgtgtggctg acgcgtgccg
     7081 accccgcgcg gagcctgtcc aaggacatgc accccgcgtt cgccgtgctg atggtcgtcg
     7141 cgtccgccgg gctcgtcgtc gccctccacc gggcccgcac ccggcgcccg gccgcacgct
     7201 gacccacgcc gcccgagccc ggccgcacgt ccgcccgacc gccggccggc aacccgacga
     7261 ttccaccacc gacaagggga acaccatgcc cgccctccgc agcaccggcc tccgagccgc
     7321 cctcctcacc gtcccgctcg ccctcggcct cctcggaacc gccgccgtgc ccgccggggc
     7381 caccccctcg caccccgcca agtccctcac ctgccgcggg aagggcgtcg atcccgacgc
     7441 ggccgtccgc caccgcaccg agaccgtgat ccacgcgccg ctgcacacca tctggaagct
     7501 gcagaccgac gtggcccgct ggcctgcctg gcagtcctcc gtcgagaccg cggaacgcct
     7561 cgaccacggc ccgctccgca ggggctcggc gttccggtgg acgaccccga ttccccccaa
     7621 ccccgcgacc cccgccacca gcctggagat cacttccacc gtcgagcagc tccggcacgg
     7681 ctcctgcctg cgctggaccg gcccggcgtc cgccgaaggg ctgcgcatcg acggcgtcca
     7741 cgtatggaac ttcaccaagg tccccggcgg cgtccgggtg agcaccgaag agacgcacac
     7801 cggcgaccag gtcgaggcga acgtccccgc cgcgacgcgg attctgcgcg agggcctcga
     7861 aaaatggctg cgcgagctga cggccgccgc cgaagtctgc gcccaccacc aggcgaggta
     7921 gggccggacc cggcgtatga gacaggcagc cccggcggca cggccggggc tgcctccgca
     7981 cgccgtgcgg ccgtggtcag acgtacgtct ggagcgtgcc gcgccgccgg acgtcgaggg
     8041 tcgcgcagtg gaacgagccg ccgaacggcg cgtagtgcag caggtcgcac gggatgggct
     8101 cgaatcccca cttctccagc gcgcgcagca tcccggtgtg gtgccgttcc gcgatcaccc
     8161 gcttctcgtc gaccatgagc acgttcatgc tgagccactt gccgcacagc gaggtgagtc
     8221 tgagcagccg gccgtcgacc ggggtgggtt ccggggcgat caggacgtcc cacgaggaca
     8281 gcacgtcggg cagccggtcg acgtcgatgt actcggggtt gaccagcacc tttccgggtg
     8341 cgagcaggac gaatgtggtg tcgatgtgca tcggggtgcg gcagcggctc tcgatctcgt
     8401 ggatgcggta gccggggccg aggtggcggc gcagccagtc gatgcccatc cggttggtga
     8461 cattgctccg ggtgacgaac aggtcgcgtc ccgcgcggac gaaatccgcc gcgtcgaaca
     8521 ccggctcgaa ctcggtgagg atgtagcgca tgggctcgcc ggcctcgggg acacggaact
     8581 ccgcgtcgaa cagttcatcc gtgagctgtg gtctcggtgc cgccgtccag cgcgcgcccc
     8641 gccggaagta gtccttgacg accgtgcggt aggagtgcgc ctcgaagtac cggcacggcc
     8701 aggccatcgg cgtctcgatg atctcgtcgc cgatcaccag caggctgtcg cgggggcagg
     8761 tgttgcagaa gccgcgggac gaccagtcgg gggtgccgaa gcgctgccgg tggtcgaccg
     8821 cgtccggacg ccggacggtg acgtcgagcg actccaggag cgcgacgaac gcgtcgagtt
     8881 cccgctgggc ccgttcgatc agcacccggg ggtacttgaa gccggcggcg agcccttgca
     8941 gccgcgccgc ccacggcggg atgttgcagg tcacgaccgg gtggctggac gggatcgtcg
     9001 cgccgtcgag gcggcctacg atgatctcct ccagcgggtc ccactcggtg tacgaattga
     9061 ccggcggagc cgggctctcc tcggtgccgg ccgccgtggc cgagggggcc gtcatccctc
     9121 gtggtccacg gcccgtgcgc gggcgccgtc ggccgccccc tccgggacgc cgggccttcg
     9181 cactgccact gccatgctcg accgccttcg atcgtggacg ccagttttcc ctaagtgaac
     9241 gtgggagaca ggtccgcgtc aacgaacagg gccgtggccg ccgctcaccc ggtgggtcgc
     9301 gggaccggga gctgggccca gaccgtcttg cccgtgcggt ccggacgggt ccagccccag
     9361 gactcactga gccggtcgac gatccacagg ccccgccctt cctccgcgag ggggtccgga
     9421 gccgcgaggg ccgggacggc acggctggag tcggagacgg cgcacaggac gccggcgtcc
     9481 tggtgcgcca gtgccagaca ggccgcgcac accagctcgg gccggggcga ttcggcgtcc
     9541 gggtgcctgg ggacggcgtg gcgcagggcg ttgccggtga gttccgagac caccaggacc
     9601 gcgtccgaga cgacgggcgc acagacgccc cacccttcga gggtggcggc ggtgaagcgg
     9661 cgggcttccg cgacggcact gtaggcgccg ctgagcgcgc acacggcgaa ggcgtcgagg
     9721 ctcgtcgccg gctgttccgc acccgtttcc gcgtggcgca cgtcgtgcac ggtcggtgcc
     9781 ggatgtgtag tcatcacgat ctccgccatg gggcatttcg ggggctgggc cgcgcagttc
     9841 aggagggcta atatcctcgt cggccgcctt ccgctgcaag tacatctgga attgcatcgg
     9901 taagtacggc cgcgtggggc ccgtttcacg ccaccgtacg tacggggccg taccgggcgg
     9961 agccagatcc tccagtaagg agacagcggt atggagtcat tgcccaacgg catatgcgcc
    10021 agcgccatcg agggggcggt gtggcgcaag agctcccgca gcaaccccaa cgggaactgc
    10081 gtcgagctgg ccgttctcgc cgacggcggg gtggcggtac gcaactcccg gcacacggga
    10141 gggcccgcac tggtctacac ccgtgacgag atcgcggcct tcgtccaggg agccaaggac
    10201 ggggatttcg acgacctggc cgggaccggc tgacgcatat gtcggccgga tagtcacctc
    10261 cgctgtacga acagttgagg cgatgggaca ctgagcgttc atccgaccaa caggggagtc
    10321 atcatggtcg ccgcgcagcc ggggcgcgtt ccgcccctgc gccgtcacat cgaacatccc
    10381 cggggcggcc cgacggtcct gcggatcatt ctgggcaccc atttgcgccg gctgcgggaa
    10441 gcggcgggcg tcacccgtga ggcggccggc gacgccatcc gcgggtcgca tgccaagatc
    10501 agccggctgg agctgggccg cgtcggctgc aaagaacgcg acgtggccga cctgctgacg
    10561 ctctaccggg tcacggacga gcaggagcgc gccgagttcc tggcgctggc ccgcgggacc
    10621 agcacacccg ggtggtggca ccgctacaac gacgtactgc ccacctggtt cgagacactc
    10681 atcggcctgg aggaggccgc ctccgtcatc cgcacctacg aagtgcagtt cgtgccgggt
    10741 ctgttgcaga cgccggagta cgcctacgcg gtctgccggc tcggcaaccc gcaggcgtcc
    10801 aggaaggagg tcgaccgccg ggtggaactg cgtctgcaac ggcaggcgct gctcaccgcg
    10861 cccggcgcgc cccggctgtg ggcggtgctg gacgaggcgt ccctgcgacg tccgctcggc
    10921 ggacccgacg tcatgtccgg ccagttgcga cacctgctgg ccatgtcgca gctgcccaac
    10981 gtcaccgtgc aggtcgcccc gttccatctc ggcgggcacg cggcggcggg cgggccgatc
    11041 acgatcctgc gcttcctgga gccggacctg cccgacatcg tctacctgga gcaactgacc
    11101 agtgcgctct acctggacaa gcgcgacgac gtcgaccact acctcgccgt gatggaccgg
    11161 ctcagcgccc aggccgagtc cccgcgcggc acccaggcca tcctggagga gctgatcggg
    11221 ggcacggagg gggactgacc cgggcggagc tgccgtctcg cctaccgctt gcgggccacc
    11281 ccgccgtact cgatccactc catggtgagc tgcttgggtc cgatgtccgc gtccggcttc
    11341 caggtcgaca cctccaccag gcccggttcg aggatctcca gcccctccag gaacgagccc
    11401 agttcggccg ccgtgcgcac ccggccccac tggccctggg tgctgacccg catgaactcg
    11461 gtgacgaagt cgcgggtggc cgcgtcctcg ctgaccagct ggcagacgac caggaagctg
    11521 cccggggcca ggcgttccgc gacccgcctg atcaggccgg cggggtcgtc ctcgtccggg
    11581 atgcagtgca gcacggacac gaacagcgcg gccaccggct ggtcgaagtc gatcagccgt
    11641 gccacctccg ggtggcccag gatgccgtcg gtgtcgcgca tgtcggcctg gatgaccgcg
    11701 gtgttgcggt tctcctccag cagcgcacgg ccgtgggcca gcacgatggg gtcgttgtcc
    11761 acgtagacca cccgggactc cggggcgacc cgctgggcga cctggtggac gttgtcctgg
    11821 gtcggcaggc cggacccgtg gtcgatgaac tgccgtatgc cctgctcctg tgccagccag
    11881 cggaccaccc gtcgcaggaa ccggcggttg ttcaccgcca ggacctgcgt gctcggcacg
    11941 accttgttca gttcctcgca cgcctcgcgg tccacggcgt agttgtcctt gccgccgagg
    12001 tagtagtcgt acatccgcgc cacactcgga acgctgacgt cgacggtgcc ggactgtggt
    12061 cgcacttcct ggctcattcg ctgctctccc gtcgctcggg cacctcgccg aggcaccacg
    12121 gccggccgct tcacgggatg tgaccgggcc ggtacggcgt ccaacatacc cagctcgggg
    12181 cggctgttgc aggtgcacgg gcggagtccg tccggaaccg ggccgaccgg gcggaatgac
    12241 ggccgggccg gtgactaggg ccgaacggtc cctacttttc cttccgggcc gtccgcgggc
    12301 caccttcggg ccgtacggat tcggccagcc ctgatccggc ctcccggctc cggggtggcc
    12361 gtggggtgtt cgaggcaccg gtccgccggt cagggggaga agttgcgctg ccaccggtgc
    12421 ccggccggcg cggcgagttg gaggccttgt tgttcgtcgt tgtctctccg gacggcgccg
    12481 gccgggccct gaccgacgct ccccccggcg ccggcgggcg gccccacacc cgcccgaacc
    12541 atgcgccacc cgccccatcg cccgctttag ttgacaagcg ccccacagct tggcgtacgc
    12601 tccccgggcg cttcattcgc tggagcggac gctatgcgtg acgcccggca tccgcccggt
    12661 cccgtgacac ggaggtctgc acgatgaaag ccttgatgtt caaagctccc ctgcaggccg
    12721 tgctcaccga gcgcgacgtg ccggagcccg cgcccggcga ggcgctcgtg aagctcgcct
    12781 acaactcgat ctgcggcagc gacctctcct tctacaaggg ggtctggcac ggcttcacct
    12841 accccgtggt gccggggcac gagtggagcg gaaccgtggt cgaggccggt ggcggcgctg
    12901 ccgacctggt cggccagaac gtggtcggcg acctcaccgt ggcctgcgga agctgccgcc
    12961 actgcaccgt cggcaagccc accctctgcg ccgacctgca agaactcggg ttcacccggg
    13021 acggcgcgtg cgccgagtac atgaccgtgc cgaccggcaa cctgcaccgg ctgcccgagg
    13081 gcctctcgct gcgcgaggcc acccaggtgg agcccctggc ggtggcgctg aacgcggtcg
    13141 accggctcgc ggtcacggcc ggcgagaagg tggcgatcac cggtgccggc ggcatcggcc
    13201 tgctgctcgc ccaggccgta cggctgcgcg gcgccgaagt caccgtcctc gccgagccgg
    13261 tgaccgaacg ccgccaagcg gcccacgcgc tgggcgtgcc gcacaccgtc ggcggcgacc
    13321 ccggcgagct ggtcgggttc gtcgagaagc accccgagct gaccccggac gtggtgctgg
    13381 aggcgtccgg ctaccccctc gccgtgcagg aagcggtaga ggctgtccgc tctggcggac
    13441 gcatcggtct gatcggctac cgcatcgagg aagccgccac gatggcgccc catcacatcg
    13501 tggtgaaggt cctctccctc caggcgtcga tggggcccgg ggaccggttc ggcgaggcca
    13561 tcgagctgct ggccgccggg gcggtcgacg tcgacgcgct gctgagccac gagttcggcc
    13621 tggccgacca cgaccgggcg ctggacgtgg cgctgcgccg cgccgacggc aacacccgct
    13681 cgtacttcaa cctccgcgcc tgaccgcccg gccgttctcc cccactcccc cagccccgtg
    13741 ctcaggaagg acgatcagat gacccggtcc ctggccgtgc aaggcggcag tccggtacgt
    13801 acccgcccct ggcccctgtg gccgcagccg gctcccggcg cggtccgggc gctggatggg
    13861 gtgctcacct ccggccgctg gtcgatcagc ggaccctacc ggggcgccgc gtcccaggag
    13921 cggcgcttcg cgcaggcgtt cgccgcgtac aacggggtcg agcactgcgt acccgcggcc
    13981 agcggcaccg ccagcctgat gctcgccatg gaggcgtgcg gcatcggcgc cggcgacgag
    14041 gtgatcgtcc ccgggctgtc ctgggtggcg tccggttcga ccgtgctcgg cgtcaacgcg
    14101 gtcccggtct tctgcgacgt ggaccccgac acgctgtgtc tggaccccgc cgccgtggag
    14161 agcgcgctga ccgagcgcac caaggcgatc gtcgtcgtcc acctgtactc ggcggtcgcc
    14221 gccatggacg cgttgcgggc cctggccgac cggcacgggc tgccgctgct ggaggactgc
    14281 gcgcaggcgc acggcgcgga gtaccgcggc gtcaaggtcg gtgcgctggc caccgcaggg
    14341 accttcagca tgcagcacag caaggtgctc accagcggtg agggcggcgc cgtcatcacc
    14401 cgggacgcgg agttcgcgcg ccgggtggag cacctgcgcg ccgacgggcg ctgcctggcc
    14461 gggcagccgg ttggcgacgg gcagatggag ctggtggaga ccggcgaact gatgggttcg
    14521 aaccggtgtg tgtcggagtt ccaggccgcg ctgctcgtcg agcagctcgg tgtgctggac
    14581 gagcagaacg agcggcggcg gcgcaacgcc gcgctcctgg acaagctgct ggccgacgag
    14641 ggctaccggc cgcagacgac ctccgagggc accagtaccc gtacgtacta cacctatgcc
    14701 gcccggctgc ccgagggcga gctgacgcac gtggacgcgg cggccgtcgg cgaggcgctc
    14761 accgccgaac tcggcttccc cgtcgccccg tgctacgcgc cgatcacccg caaccgcctg
    14821 tacgacccca ggagccgtgg ccgcttcgcg ctgggtgtcc agcacgagag ccgcatcgat
    14881 cccaagcgct tcgagctgcc ggtgtgcgag gaggcggccc ggcgcaccgt caccgtgcac
    14941 cacgccgccc tgctcgggga cgagagcgac atgcatgaca tcgcgacggc cttcggcaag
    15001 gtcgtgcggc acggcgccct gctgaccggc tgaaggcggc gggccgcagc cggcccgccg
    15061 gagcaaccgt cccgcgaccc gcccacgaaa tcggggagac catgcacgtc accgccatca
    15121 ccatggaaga caccagcttt ccctaccggc tcgggaccga gtgcgccgag gagatcgtcg
    15181 cgcgcctcgg cgagcgcgcg gccagccgct atctcgtggt gtgcgacacc acggtggccg
    15241 cgctctacgg acgcgacctg gtcgcccggc tggagaagga cgccggtccc gccgtcctcc
    15301 tgacccatcc ggcgggcgag gtccacaagc gcatcggcac cgtcggcgac ctcgccgagc
    15361 aggccctggc cgcgggtgcc gaccggcgca gcgtcgtggt ggcgctgggc ggcggcatca
    15421 ccggcaacat cgccgggctg ctggcctccc tgctgttccg cggcatcacg ctggtgcacg
    15481 tgcccaccac cgtggtggcg atgctggact cggtgctgtc gctgaagcag gcggtcaacg
    15541 cgagtttcgg caagaacctg gtcggcacct tctaccagcc ggccgaggtg ctcgccgaca
    15601 cggcgatgct gcggacgctc ccggcgcggg agctgcgctc gggcatgggt gaggtggtca
    15661 agaacgcgct ggccatccgc ccgtcgatga tcgagcggct cgccgcggag ctgcggccgg
    15721 acgcgcggta cgaggacgcc gcgatgcggt ggatcatcga ggagagtgtg gccgccaagg
    15781 cgcaggtcac cggtgcggac aagcacgagc ggcgggacgg tctggtgctg gagtacgggc
    15841 acaccaccgg gcacgccatc gagcacgccg cgcggggcga ggtcgcgcac ggcgcggggg
    15901 tggccatcgg catgatcgtg gccgccgagg tgtcccggct gctcgggcac gcctccggcg
    15961 acctggtcgg tctgcaccgt gaactggtcg ccaaggcagg tctggagggg tccgtcccgg
    16021 cactggtgga cccggcggac gtcaagcact ggctgaccta cgacaacaag cgcggctata
    16081 tgccctgccc gcccgccgcc accccgatgg tgctgctgtc cgctcccggc gaggtgctgc
    16141 gcagcggccc gctgccgctg gtgcccgtgc cgctggagct gctgggccgc gccgtcgacg
    16201 cgctggcggc gcccgcgggg cagtcggccg gtgccgagcg cctgtcgccc gccccggctt
    16261 gacctgcggc ggaccccgcc cccgtccctg ttcccgccgt ccgttccgtc ccgtgtggag
    16321 ttctagtgcg tgtgctgcgg ctgaccccgt tcttccacca cgaccaggtc gagagctggc
    16381 ccgccgagta cgacgccgtc ggcgggatgc aggtgcagat cctgcggctg tcgcgtgagc
    16441 tggcggcgcg cggtgtcgaa cagcaggtgc tgaccgtcgg cttccccggc ctgccgaagc
    16501 ggcgcctgga ccggccgggg ctggtggtgc gcgtgacccg cgcgccgctg cccccgatcc
    16561 ggtcgcagct caccgggctc gtcggcctca accaggcctg gctggccggg gcgttggccg
    16621 cctgtgtgcg gctgcgccgg cggtggcgcc ccgacctgat ccatgtgcat gccgacgggc
    16681 agttgtgggc gctgctggcc gggccgctgg cggcccgcgt catgggcgtg ccgtactgcc
    16741 tgacgctgca ctgttcacgg ctgtcggtct acgagccgat gtcccgggtc gaccagttcc
    16801 agcaccggct ggtgcgcgcc gtcgagagtc atgcggtgcg gcgcgcggcc cgggtgtccg
    16861 ccctgacctc ccgtacggcg ggtgtcgtcg cgcgggccct gtcgatggac cccgcgtcca
    16921 tcgacatcgt gcccgattcg gtcggcgacc tgtcgccccg gcctgccggg gaggtggccg
    16981 ggctgcggcg ttcgctggag atcgcggagg gggccgccct ggtcggttac gtggggcggg
    17041 tggcgcacga gaaggggtgg cgggacttcg tcgccctggc ccgccgctgg cagtcgctgc
    17101 cggggacgcc gcccgcggtg ttcctggtgg tcggggacgg gccgcagcgc gagcggatgg
    17161 gcaaggccgt cgccgacgcg gggctgaccg accggttccg cttcaccggc ttcctgccgc
    17221 acgccgacat cccggcggtg atgaccgcgc tggacgtgct ggtcatgccg tccgcccacg
    17281 aggagttggg cggcagcgcc atcgaggcca tgatgtgcgg cacgccggtc gccggttact
    17341 cggtgggcgg actgcgggag acggtgggca ccgtcacgcc gggtctgctg gtgccgcgcg
    17401 gggacgtggc ggccctcacc gaggccgtac gcggcgtcgt ggaggagccc gaaggacccc
    17461 gggggcgggt ggccggcgcc cgggagcggc tgggcacggc gtacggcagc gggtcggcca
    17521 ccgaccgggc actggagcac tacgcccacg cgctgcgcgc cgcgggaagc gcgcgatgag
    17581 cgccccgccc gcccgcaccg gatcgctgtg gcgctgtgcc cgctatctcc gtccgcaccg
    17641 ctggctgatg gtgggagcct gcgccgccgc cctcggctcg atgctcgccg ggctgtccat
    17701 gccgctggtc ctccagcggc tggtggacgg ccccgtcgcc cacaaggaca tggcggcgct
    17761 gccgtggacc ctcatcggct tcacggtgct ggggtgcctg gaggccgtac tgctgggggc
    17821 ccgccggctg ctggtcgtcc ggccgtcgac acggctggag acgacgctgc gcgcgggcct
    17881 gttccgtcat gtgcagcggc tgccctcgtc gttccacacc cgctggagtt cggggcagtt
    17941 gctgtccagg acggtctccg acatcgccga gctgggccgg tttttcgcgt tctccgcggt
    18001 gtatctgctg gtcaacacgg cggcgctggt ggcgggtctg gccgtgctgg cgtacctgtc
    18061 gccgttcctc gcgctgatcg tgctggtgac gtatctgccg atggtgctcg ccaccatcct
    18121 cttcgagaag cgcttccacg tggcggcccg ctccgcgcag gaccagagcg gtgacctgac
    18181 caccaccgtg gaggagtccg tactgggcat ccgcgtgctg aaggcgttcg ggcgcggccc
    18241 ggagaccgta cgccgcttca ccgcgcaggc ccgcgcgctg cgccgcaccg aactgcgcaa
    18301 gatctccctg accgccgccc tgtggtggct gatcaccgcc ctgcccgagg tgggcatcgt
    18361 cgccctgatg ggattcggcg gctacggcac cgccaccggc acgctgaccc tgggcaccct
    18421 gatggcggcg atcaccgtcg ccacctacat gcgctggccc gccgacaccc tgggctggct
    18481 gatcgccgac gccagtaccg cggcgtccgc cgccgaccgg tactggcagc tgcgggacgt
    18541 cccgctcgcc gtgcgcgaac cggccgcacc ccgcccgctg gcgagtccgg tgcgcggcga
    18601 gctgcgggtc gaggacgtgc actaccggct gccgggcgcc ggcgacgccg tactgcgcgg
    18661 catcgacctg acggtgcgtc ccggcagcac cctcgccctc gtcggcgcca ccggctcggg
    18721 caagtccacc ctcgtctcgc tgctgtcccg gctggacgac cccacccacg gccggatcac
    18781 gctggacggc accgatctgc gcgacctctc gctggacgcg ctgcggtcgg tggtgacctg
    18841 cgcgttcgac gatcccgtgc tgttctcggg gaccgtacgg gacaacgtcg ccctcggcct
    18901 gccccccgag gagcgcgacg acgcccggat ctgggaggcg ctgcggctgg cgcacgccgc
    18961 cgacttcgtc gcggccctgc ccgaacagct cgacacccgg gtcggcgagg agggggtggg
    19021 cctgtccggc gggcagcggc agcggctggc gctcgcccgc gccgtcctgc cccgccccgc
    19081 cgtcctggtc ctggacaacg cgctgtccgc gctggacgtg cacaccgagc gggaggtgga
    19141 ggcggcgctg cgcaccgtga tggcgaacgt caccaccgtc ctcgtcgccc accgcccggc
    19201 cactttgcgc gcggcggacc gggtcgcgct gatcgccgac gggcgggtgg ccgccaccgg
    19261 cacccacgac gaactcatgg ccaccgaccg gcgctaccgc cacctgctgc gttccccggt
    19321 caacgacctg gtgccggacg gaccgcaggg cccgccgtcc caggaccccg cacggaaggt
    19381 acgcgcctga tgcccgagga ccggcaggag aacgacacgg ccgccccccg gccctcgggc
    19441 gcccctgacg tggaccgggc tgcggacgag gccgacggca ggccggacga ccggcggctg
    19501 cgggaacgcc gcaaccagct gctgcgcacc ctgctggcgc ccgagcggcg ccggctgacc
    19561 cgcgccgtcg gcctggcgct gctggagaac gtctgcgcgc tcgtcacccc gctgctgatc
    19621 gccgccgcca tcgaccgggg cgtgcccgcg gcggcggacg gccgctgggg tccgctgacc
    19681 gcctacgcgg cgctcgcgct gaccgccggg acggccaccg ccaccctgcg gtacggcttc
    19741 ctgcgctact ccgggaacat cgcgcagacc ctgctgttcc ggctgcgctg ccgcaccttc
    19801 gcgcacgccg tgcgcctgcc gctgtcctac cacgaggccg cgccctcggg cagcgtcgtc
    19861 gcccggctct ccagcgacgt ggagtccgtc gaggaggtgc tggagatggg tctggacggc
    19921 ctgttctccg ccctgttctc gatggtgggc acggtggccg tgatgctctg gctcgacctg
    19981 ccgatggccg ccgtcgtact cgccctgttc atcccgctct acctgctcac ccgctggttc
    20041 cgggaccgct cgcggcgcgc ctaccggcgc acccggggcg ccaccgagcg gatcgtgcag
    20101 cacaccggcg agacgtacaa cggcatccgt gccgtgcagg cgttccgcaa ggagggcgag
    20161 aacaccgcgc ggctgcggga gatggacgcc acctatgcca ccgcgcgggc cgcctcgggg
    20221 cgggtcagcg ccttcttcag cggcggcgtc aagctgatcg gcaacctctc gctggctctg
    20281 ctgctggccc tgggcgcgtt ccgtatcgca agcggccacc tcgaagcggg cgcgctgacc
    20341 gcgttcctgc tgtacgtgca ccggctgtac gacccgatcg acgaactcgc ctcgttcgcc
    20401 aacgcgttct ccgccgcgtc ggccggactg gaacggatcg gcgtcctctt ccacgcaccc
    20461 gacacactgc ccgagcccgc cgaccccagg ccgctgccgg cggtggccgc ccccggccgc
    20521 gtccgcttcg aggacgtgcg cttccgctac accgccgcct caccgcacgt actggccggg
    20581 ctggacctgg atctcgcgcc cgcggagacc gtggcgctgg tcggtacgac cggggcgggc
    20641 aagtcgacgc tggccaagct gctggcgcgg ctgtacgacc cgacgggcgg ccggatcacc
    20701 ctggacgggg ccgacctgcg cgaggtggcc gacgccgaac tgcgctccgg tgtctgcatg
    20761 gtcacccagg aaccgttcct cttctccggc tccgtggcgg acaacatcgc cctgggccgg
    20821 ccggacgcca cccgcgagga catcgtcgcg gcggccgagg ccgtcggcgc gcacggtttc
    20881 atcagcgcgc tgcccgaggg gtacgacagc gacgtccaca agcgcggcgc cggtctgtcg
    20941 gccggccagc gccagctcgt cgcgctggcc cgggtgatgc tcagcgcccc ccgcgtcctg
    21001 atcctcgacg aggccacctc cagcatggac gcccccaccg agcgggccgt gcacacggcc
    21061 ctgcaccggg tgctcgccgg ccgtaccgcc ctgatcatcg cgcacagcct gaccacggcc
    21121 gccatcgccg accgggtgct ggtcctggag aacggcgtgg tcgtggagga cgggccgccc
    21181 gccgtactgg cggcgggcga cgggcccttc gccggcctgt accgcggctg gctgtccgcg
    21241 accgacgggc gcacccacca ccccgcgcac cactgaccgc cgcgcacccc tgaccgccgc
    21301 ccaccaccga ccgaaaggca agcacgccat ggagcaccta cggggaccct cgccgctggc
    21361 gaatcccggc gcccggcacc cggaactcct cgggcccgcg caccgcgacg gtttcggcga
    21421 cgaggccgcg gaccgcgtgt gggacgtctg cgtcatcggc agcggggcga gcggggccgt
    21481 cgccgcggac cggctggtcc gccaggggct cgacgtcctg atggtcgagg agggcttccg
    21541 gctcgccgga cacgtggacc tggacgaggc cgagaccctg tgccggcagg ccgtcgcccg
    21601 cgacgacgaa ggcaactgga ccgacgaggg ctggccgtgg accacctcca acctcggcgg
    21661 cggcacggtc ttctacggcg gcgcctcgtt ccgctaccag cccttcgact tcgacccggg
    21721 caccctcatc gacaccggca ccaccgaggt gcgctggccg tacaccctcg cagagctggc
    21781 gccctactac gaggtgctgg agcggcgtct gggcgtgtgc ggcggcccgc cggccgaggg
    21841 ctcgaacggc gcgcggcaca gccgcggccc cgcccacgag ccgtccgccg ccgcgcgggt
    21901 gctgtacacg gccggcacgt cgctgggcta caagccgttc cccacgccgc tggccatcaa
    21961 ccgtgacccg tacgaggggc gcgccgggtg cgaccgggtg tcgctgtgcg tcagccacgc
    22021 gtgccccacc ggcgccaagg gcgatgtcgt cgcggtcttc ctggcgccgc tggccgccca
    22081 ccccaacttc atgctgcgca ccggcgtccg cgccgtacgc ctggaacaga accgcaccgg
    22141 cgaggtctcc gcgctgcgct gcctggaccg ggtgagcggg cagaccaggg aggtgcgcgc
    22201 ccgcgcgttc gtcctggcgt gcaacgcgat ccagacggcg gccctgctgc tgcgctcccg
    22261 cacggcgtac tccccctccg gcgtcggcaa ccactccggc ctggtggggc ggggcctgtg
    22321 cgtcaagctg agcgagtacg tcagcggcgt cgtgcaggcc gcgccggagg tcctcgcgga
    22381 cccggacgtc cacaagggcc cgttctccac cgtggcgttc ctggaccact acctggacga
    22441 ggactgcccc acgggcgtgg gcggcctgat ctacgagtcc aagcgggacc gggcgcccaa
    22501 gctcgtccgg gacgcgctgg aactgcggat cgagacgatc ctgtccgacc accccaacct
    22561 ggacaaccgc gtcgggctgt cccgctacgt cgacgaggac ggcctgcccg ccatcgtcct
    22621 cgactaccgc accgacccgc gcgaccaggc ccggctgcgc tacatgaccg gacgctgcga
    22681 gcggctgctg cgcgccgccg gagcggacgg catccgccac aaggccaccg gtttcgcgca
    22741 gggcagctcc cacctgcacg gcacctgccg ggccggtgac gacccggccc gttcggtggt
    22801 ggacggctgg ggccgggtgc actcggcgga caacgtctac gtcgtcgacg gcagcttcat
    22861 gccgtacccc ggcggtctca accccactct gaccatccag gcccacgccc tgcgcaccag
    22921 caaggccgtc gcgtcccagc tggcggcccc gcacgccgct catgcgtgag ccccgcacgc
    22981 cgcccatgtg tgaaccgtac gagaggacac cccgatcatg accaccgtgc aatggccgcc
    23041 gcgtacccgg cgcgtccgcg cctaccgcaa catcgtcatc gacggcgcct gcaacctgcg
    23101 ctgcacctac tgcgaagtca aggcgatcaa ggtcgaccag ccggccacca acgactcgct
    23161 ggaccggatc ttcgccaagt acgagcagga caacgtgctg ttccgggtgg agtccaacgg
    23221 tgagatctgc ctctacccga agatcctgga ccacctccag cagcgtgccg ccgagggctg
    23281 gcagatcgag gtgctgagca acggcacccg cctgccgcgg tgcctggagg gccgggagaa
    23341 cctgatgtgg gtcttctccg tcgacggcca caccgcccgg atgaacgaga agcgcggcct
    23401 gagccaggcg caggtcgacc gcatcatcga cacggcggtg gagctggacg ccgaactcca
    23461 ggcggtctac cacgaccaga ccatcgacga ggtgaacgcc ttcatcgaca cgctgtccgc
    23521 ccgcggctac aagggcctgc tgcacttcat gccgctgctc gccttcaagg ggcagccgct
    23581 ggaggtcaac ctgcgctacg aggacctgca cccggcggag ttcctcgccc cgccggagta
    23641 cttccggcgc tggaaccaca tcttcgagac gggcaagcgc gacgcggtct gcgaccagat
    23701 caccaacggc tacaactact cggtggccga cgacaagatc cagatggtca agtgcgactg
    23761 ctactcggtg ccgaagcacc tgtaccacga cttcggcccc atccgggagt tcgacaactg
    23821 gccgtgcggc acctgcatcg ccaaccagga gttcaacagc tcccggccgc gcatgctggc
    23881 gcccgagggc cgcatcccgc tgcccctcgt atgacggacg gcaccggtac gcccgtcacc
    23941 cggcggttcc tgctcgtccg gcacgcccag gccgaggtca acgtcctggc ggacgacgac
    24001 ctgatggagg ggtacgacac cgacgcggac ctcacgccgc tcgggcggga acaggcacgg
    24061 gcgctggccg ggcacctggc cggggaccac gcgtcctggc cgggcccggc cgggcccggc
    24121 ggctaccggc tccgcaccag cccgctgcgg cgggccgtgc gcaccgccga gacgctggcc
    24181 gcggcgctgg ggctgacggc cgtcagcgac gcccggctgg ccgaggtgcg ggcaccgcgc
    24241 aggttcccgc gcccgctggc ggtacgggag tgggacgccc tgctggagca gcggctgcgg
    24301 cacccggagc gggagttcgc cggggtggag agctgggcgg cgcagcgcgc ccgcgcccgg
    24361 gagttcctgc gcgagtgcct ggccggcccg ccggcggcgg gcttcgtgct cgtctcgcac
    24421 gccgagacga tccaggcgct gctgatggaa ctgctggacc tcggcgacgg gatgctgcgc
    24481 tcggcccgct tcaaggtcag caacaccggc gtcttcatcg tggaccgaac cctggacgga
    24541 acggaggagc catgcagttc cctggtggtg gccaactcga agagccacct ggcccgtacg
    24601 gcgtgacggg cgcaccgctc gccggcgcgg ccggggaccg cgtccggctg ctggtggtca
    24661 agtgcctcag cgacgagacc ggtgaggacc ccgacgcgat cgtcgcccgc ggtcacctcg
    24721 acgtgggcga ccgggactac gccaacatcg tcaaccggct ggagtcgtac ttcgactgct
    24781 cgctggacct gctggccggc ggcaaccggc ggctcgtcgt ggacgacctg tgcgaccggc
    24841 tcggcctgct gcccctggag gcggtccatg tctgagccgc cggccgcatc cctgggcgcg
    24901 ccgctggacc cgccgggtcc gctccgggcg ctgctggaga tctacgacga gggtttcacc
    24961 tgcgacacct ggggcggggt ggagaccgcc ctgtggcacc tggccgaggg gctgcgggag
    25021 cacggcgtgg aggcggagtt ctaccgctcc acggagggcg ccgacctcgg cgcgctggcc
    25081 gagcgggtgg tgcgggagcg ggtggatgcg gtgtttccgc tggtggagag cccactgttc
    25141 gtgggcggag cgtcccgttc ggagcgtccg gccgcgggcg agggccagcc cgaagtacgc
    25201 gagctgcggc ggcgcgtggt gcggatctgg cacgacgtga gccgcctgtc gcccggcctg
    25261 tccaccccgc cgccctgccc ggtgcacacg cccggcgcgg ccgccccgtc cggcggggtc
    25321 tgcgcggcgg cgggagtgtt ccccgacggc ccggcgcggg aggtgttcct gcgcgacctg
    25381 ccgtggaccc gctgcttcgg ctcccgtacg tacatcccgt gggccgtcga ccacctgccg
    25441 ccggcggatc tgcgcgaccc gttcggcccg gtgctgctcc agctcggcaa gacctcggtg
    25501 gaccaggccc gggtatgcct ggaacggctc accggcgccg ggctgccggt ccgtgtggtg
    25561 ttcgcgacct ggtcgaagga ggggcgggcc gcgcgcgaac tggtcgcgcc gtacgccgcg
    25621 tccggcgccg tcgaggtgct ggactcctac gacatccgca ccgagtggaa gcgggtgtac
    25681 gcgggagcgc ggctgttcgt gctgccctcc gtcttccacg agacgttcaa cttcgcggcg
    25741 gcggaggcgc tccagctcgg cctgccggtc gccacgctcg gcgactgcgg ggccctggcc
    25801 gacttcgcgt cgctgcgggc ggagacggtg gcggagctga tggacgcggt cgtcgcgcgc
    25861 ggcgagtcgg tccgtccggc gcggcgtccg tggaccggct ggcgcgaggt cgcccaccgg
    25921 tacgcgacgc tcatcgccgc accgcgccgc gcaccggcgt tgggggtgta aggccatgac
    25981 cggtctgatc gaggaactcc gggaccacac cacgctgtgg atctcgcccc accccgacga
    26041 cgtggcctac tcctgcggcg gtgtgctggc cgcgtgcgcg ggctccgcgc cggggctgct
    26101 gctgaccgtc ttcacccgtt ccgcgtgggc gctgcccaag cggctgcggg ccgccgggcc
    26161 cgaggtgatc agcgcccgcc gtgcggagga ggagcggcgg tactgccggg cccgcggcct
    26221 ggcgcggtac gtgccgctgg ggttcgacga cgcgagcctg cgcggttacg acgacgacac
    26281 ggagctgacc gcggacccgg ccgccgaccc gctgcgcgac cggatcgccg aggccgtggc
    26341 ggaggcggtg gccgaactgc gccccagcct ggtgctcgcc ccggcggccg tgggcggaca
    26401 tgtggaccac cggctggtgc acgaggccgt acggcggtcg gccggtgacg gcgtgcggcg
    26461 gctgtactac gaggacctgc cctacgccgc gcaccacccg cgcgccgcca cggagaaggc
    26521 gctgggcgag gaggggctgt ccctgtacgc cgtcaccggc atcgggtccg tccttgagga
    26581 caaggtgcgc ggcatgtaca tctacggctg ccagaccgac gacgagtgcg tccaggaagt
    26641 gaccgggtac gcccgcgagg cggccgggcc cggggacggc acccatgtgg agcgggtgtg
    26701 ggcgccgtcg ccggccgcgg ccggccgggc cggatgagcc gcggccggcc gtcccgcgcg
    26761 gcggcccggt cagcgcagcc cggtcacgta ccgggccagt tcgccgaggt cgtccgcgat
    26821 cctgcgggcg gtgtccgggg cgggcgcggg gcagcggcgc agccagctct tgacgttcca
    26881 ccacagggcg tcgcccgcca gttccagggc ggcgtcgaag gcgcggtcgt cgccgacggc
    26941 cgtccgcagc gtggccaggt ccgccgggtc caggcggtgt tcgacgacga aggaggagat
    27001 ctccgcctcc agggggccgg tcccgcccca gatccagtcg agcccgaacc ggcggaccac
    27061 gggcggcgcg cccggggccg ggggcgcgcc gacctgccag tgccagctct ggtgcgagta
    27121 cggcagcgag gtgcggaaga cccgggcgcg ggtgccgccg aaggcggcgc ggcgcggcag
    27181 gtggcggtcg agccaggcac cgtccacggg gagcgggcgg gccagccggt cgcgcagccg
    27241 ctccagggcc gtggcgagcc gttcgcgcgg cgcgtaggtg acggtcgggt ccaccggacc
    27301 caggccgccg aggtggtcga gcgcgtgcca gtagcgggcc acggcttcga gggcctggcg
    27361 gcggtgccgc ccggtcatcc ggggcagttc ggtggccagc gggcgcagac cgtcctcgtg
    27421 cccggtcacc aggtagccgt cgaggtggtg gcggacgggc ggcaggaact cgcccagcgc
    27481 ctcgacggcc tcggcgccct gcgcaccgtg cgggccggtg ccgatgaagc ggaagtgata
    27541 ggcgcggggg cgggcgtccg gcgcgccggg gattccggtg gcgggctcgt cggcgacgag
    27601 cgagaagggg gtgttgcggg ggctgatgcg gagcgctccg gtcgccgggg gtgtgctcgt
    27661 ggcgtcggcc gggccggccg gtctcgtacc cgcgctgtcg gccgggccgg ccggactcgt
    27721 acccgccccg ggcgcgtcgg tggccgtggc gcgcggtccg tacgccgcga ggaacgggcc
    27781 gcggaacggc gtcacccggt agacggtggc gtcggcgggc accgcgcccc cggacctggc
    27841 acggtccgtc aggcggtccg cgtcggcggg ggcgagcagt tgccacagcc gcccggcgtc
    27901 ctcgcgtacg gcggaggtcc gggtcagcgg ccgtatcccg gctccgtcca cggcgtacgt
    27961 ccggcccggc gaggcgcaca cgacgtcgcg cgcctcgggg tagcgccggg ccagcgcgtc
    28021 acggaccgcc cgcgcggtgc cgccggtgtc cggctggtcg tcgacggcga cgacgaccgt
    28081 gcccggcggc agggtggcgg gcagccggcc ggtctcggcc gggacgagcg agatccggcc
    28141 cccggtgcgc agcgggcgca gcgaggtcca gggggcggcc gtgcgcccgg cggccgccac
    28201 ggccgccgcc cacaggggcg cgaggtagga gccgccggtg cggatgccca ccacgaacac
    28261 cgggaccggc tcctcggtgg ccgccagcca tgcggcggcc tggccgtgga ccagccccac
    28321 gtcggcgagg tcgtacgcgt agcactccgg cgtcttccag tcggtggcgt gccgcagcag
    28381 cgcctcggcc gccgtgtcgc cgcgtgccgc gccggtccgc cacaggccgg cggtgtacgc
    28441 ggcggtccgt gccatggcgc gttccaggaa gcccggcccg ggcgccggtg gcgcgaactg
    28501 ccccccggga ccggcggcga cggcccgcgc gaggtcctgg cacgcctgcc ggacctcgtc
    28561 cagcagagca cgggcggact cgggcgcggt ggggcacgcg gcggtgtcgg cgaggagctg
    28621 ctcgatggag caggcgcacg cgtagcgggc ctcggcgctg ccgagccgga ccgcggaggc
    28681 cacggcggcg cggcgcagcg ggggcggacc ggccggtgct gccgtggccg gtgctgccgt
    28741 ggccggtgcc gctgcggccg gtgcttccgc ggccggggcc gcgacaccgt cggcgcgtac
    28801 gtccggccgt cccgcgaacg ccccggggct ttccccggaa aacacctcta ccgtccgcgc
    28861 attcgccgtt tccacgttat tcctcctgcc gtacggtttc ctgtccgacc ctggtccgat
    28921 ctttttgcac gaccgacagg aaatgactgt ggacgcgtcg tcgatccacg ttcaacagtt
    28981 catcgagaaa aaggctgacg atgactcaaa atttcgcgac cctggccgaa atccccacct
    29041 gcccgcggaa tgcggagggg aatccccgcg tattcgtctc ggcttcgggc gcctatgtga
    29101 ccgacgacgc gggaaaacgc tggatcgact tcgacaacac ccggggttcg gtcctgctgg
    29161 gccacggtga cccggaggtc gccgaggccg tcggccgcgc ggccaccggg gcgctgggca
    29221 ccgccaccgg ctggagcccg ctgctggaca cggtcacctc ccggctgctg gagctgtgcg
    29281 gcggcgaggt cgtcggcctc ttccgtaccg gcacctcggc cgtgcgcgcg gcggtgctcg
    29341 cggtgcgcga ggccgtcggc gcgcccctcg tcctcagctc cggctaccac ggctacgacc
    29401 cgatgtggta cccggcgaag gcgccgttcg agcccaacgc ggacggcatc gtcgacttct
    29461 tcttcgacct cgacgtcctg gccgggctgc tgcgcgacgg ccgcgagcgg gtggccgccg
    29521 tggtcgtctc ccccgaccac atgcacctgt cgccgcgctg gtacgagcgg gcccgcgcgc
    29581 tgctcgccga ggcggcggtc ccgctgatcg tcgacgaggt gaaggtcggg ctgcgctacg
    29641 ggcccggcct gtccaccgcc gggctgctgg acgcggacgt gtgggtgacg gccaagggcg
    29701 tggccaacgg cttcccgacg gccgcggtcg gcgggtcgcg gaccctgctc aagccgctgc
    29761 gcgaggtgtc gtacacctcc ttcttcgagc ccaccgtgct ggccgcggcc gagcggaccc
    29821 tggcccgggt ggccaccggc gagccgcagc gcaccgtacg ggagacgggc gacctcttcg
    29881 tggagcacgc gcgctccgca ctcgccgcgg cctcgctgcc cctggaagtg gcgggcaacg
    29941 gcaccttctt ccagttcgtg ccggccaccc gcgaggtcaa gaaggctttc tacaaggcga
    30001 cggaggagga agggctgctc ttctaccgca acgacaacca ggccgtctcc gcggccttcg
    30061 gcccggacgt cctggacgac gcgcgggcgc ggttcagccg cgtctgcgac cggctcgccc
    30121 cgttcgccgc ggccggaccg gtcggcgagg aggcccggta ccaggctgcc tggagcgtca
    30181 tggacgggct gcgcgaggcc gagcgcgacg cgcgggagac ccgggagtgg gtcgaccggt
    30241 tcctggacga ctgaccgtac gcgccgctcg caccctcgga cacgaaaggg caagcaccat
    30301 tcccatggac agaccgtcga accccaggcc ggccgacccg gaaagcgcgt acggcgccaa
    30361 atgtgcccgc ctcctggaac tttccaccca cccccggttc acctccgtcg ccctgcccgt
    30421 tttcccgctg gcggacggga cggcccggga attcctgaag agcgtccggg acgcgggcgg
    30481 gcaaaccggc ggagcggccc cgcagaacgc cgccggggat actggcgaaa cgctcccgca
    30541 gaacgccgcc ggaggaaccg gcgaaacgct cccgcaggac accgccgaag aactcgtcac
    30601 cggctacgcg cgattcctgc gccggcagtg gcccggcctg gccgacgaga tcgcccgcac
    30661 ctgcggaccc gccccctgga tcgtgcgcag ttcgggcgcc gaggaccagg aggacaacat
    30721 caacgcgggc ggctacgaca gcctggtctg cgccgggccc gaggagctgc ccgccgtcgt
    30781 cgcggccgtc gtcttcagcg ggtacggcga acacgccgtg gcccagcagc gcctggccga
    30841 cccggacttc cgccccgcgc cgatcgcggc gttcgtacag ccgctgatcg acgcctccgc
    30901 cgtctcaggg ccgccgcccg ccccgcagga gaccccgcgg ctcggccgcc cggagacgga
    30961 ccggaccgcc cgcctgctgg ccgccctgca cgaccacttc ggcatggcgc gtctggactg
    31021 cgagtgggtg ctggagaccg acgcgggcac cgtgtccgtc accagcctca ccgagtacga
    31081 ggagggcagc ggtgtcgtcg ggcagctctc cctcggcttc ggcttcgcct ccgcccagcg
    31141 gctggacggc accgacaaca gcgtcgtgtg gctgcccggc gacggccgga cgccgctgtg
    31201 gcgcggtgag gtgctgcggt ccgtacaggt gcgggccgcg cacctggtcc aggtccggcc
    31261 cgccgtcgcg ttcgacccgg cgccgacggt acaggtgctg accgacgagg accgggaggt
    31321 ctgggaggac gcccacaccg ggcgcccggt ggacctgctg gtgcccccgc ggcaggtggc
    31381 cgccaccgcg ttcctggccg ccgcccggct ggacgacgcc tggacgcagt acctgcggct
    31441 ggacgagggg cagcgggccg ccaccgggca cgtcctggtc gagcgcggca gcccggccga
    31501 gcacgccgcc gtgatgttcc ggcagtacgg cgtggccgtg ctgcggtgcc gggcggagga
    31561 cgtgccggag tcggcgtcct acgtcctggc cgacccgtgg gcggaacgct gctacttcgg
    31621 caccggccac ccgccccggg cccgtaccgt gccgcgccgg gtcgcggccg tcccgtccgg
    31681 ctgccggctg ctgttcgacg agcgggcctg cggacgggcg gccgaggccc tggtggacgg
    31741 gcggcggccc ggccccgaga cgatgccggg ttacgaggaa ctgcggacgg cggcccacct
    31801 ctcccccaca gcgcgcgatc gcctggtcgc gcgcagcttc ctgcccgacc ccgaatgcca
    31861 ccaccgggac ggcacggcgg tgacctcccc cgccttcgtg gcccaggcgg ccgcggccgc
    31921 actcggcctg ggggccgatc ctgcgcgcct gctggaggcc gtgccgcagg aggccgccgg
    31981 atacgtacgc ggcctcgtgg ccgcccgctc cgccggtcac gtcgcggccg tactgccgcg
    32041 ctgcgcccgg ctgatgggcc cgcagcgcct ggcggcggcc accggcgggc cggacgtacg
    32101 gctggcggcc gccctggccc ggttcgacgg ccgcgacgca ctgtccgaca ccgtcctgcg
    32161 gcgtctcctg ccgccggtcc tcgccctggc ggacgccgac ggcggggcgg acgcggccct
    32221 ggacccgctg ctggcggtcg agtccctgac cgacgccatg gacgcgctgg acatccacgc
    32281 ggaccacgag cgcgacgaca tcctcgtccg cctgctggac gccctgccgc tggaagaccc
    32341 ggaggcggcc ggggaactgt gccggctggc ccggcgttcg tccctgccgc ccggtgagac
    32401 ctcccgcctg gtggccaccg ccgcggccga tccggacttc gccgcccgcc acctggcgct
    32461 ggagcgctgc cgggtggccc tgtccgccgc cgaccccgcc gccgcacccc gccgcgcccg
    32521 tgagctggcc gccgcctacc gtgcgttcgc ccgcggtccg ctgctggacg gggacggccg
    32581 ggtcctgctg aacctggtcc gctgcgatct gatcgagacc tacgacgcgg cgctgaagga
    32641 tctgctcctg aagctggtgg accgccccgg cccggtgctc caccaggggt atctgggcgt
    32701 catgctgggc tggctggagc tggccgaggc attcggcccg acggcccgcg aggcacgggc
    32761 cgtcgaggtg ttccggacgt ggatcgaaga gtggcgggcc gggccgcccg ccgaggacca
    32821 caccatcgag gagggcgcct cgtggcagcg gctgctggaa agcgccgccg acgccaccgt
    32881 accgccccct gccccggcca acgcgcaccg gctgcacaac gccctccacc agtggctgct
    32941 ggcgacgacg gaccgctatc cggccgagcg ggcccccagc ggcgtcgccg ggctccacgc
    33001 ggtggcggac cggttctgcc ggggcggcaa caagctgctg cggctgaccc gggactcctt
    33061 cgagctggac gtccctctgt cgctgcacaa ggcgagcctg ctgttcacgc ccggcaggat
    33121 cgaggccgag tggagcgagc agccggacgt caccgaggag gagaccggcc ggatcgccgc
    33181 cttcgaggtg ctgctcgccc ggttcggcga ctggttcccc ggcgtggagc tgcgctccga
    33241 acgcctgctg gccgcgggga cgtggacgct gcgcatcgag gcccgcccga ccgggcaggg
    33301 gcacttcgac ctgccaagga tgcggctcgt tctggggctg ttgcggacgc tgttcgacgg
    33361 ctcgtacgac ttctcgtacg tgcccgtcaa ggaagtcacc cacctgtcgg acgccttcgc
    33421 ctccgcacgc tgggcagccg tcttcgcctc tctggtggag taccgcacgc actacgacga
    33481 ctcggcgcag tacgaaaccc tggagacgct gcccctggcg ctctcgatgg gcatgctgtg
    33541 caccgacacc tggacccggg agacggtgct gcgcctggcc gacgagagcc ccgacgcggc
    33601 ggtctcgcaa ctcgacgcgc tgatcgagga gttgcgggag gagaccgccc cggccgcctg
    33661 gacgctgctg ttccaccgga cgcagcagac ggctctgttc ctggccgcgc accatccccg
    33721 ggaggccctc gtcgccctcg ccgcccgccc cacggcggcg tgggcgaaca tcctggccac
    33781 ggccgtactg ccccgcgccg acctgcgcga agccctgcgg gccgcgctgc gccaggacgg
    33841 gccggacggc gcactgacca cgctggtact gcggcacgca ccgcatctgg tggtcaccgc
    33901 ggccgacgcg gcggaactcg cccgggcggc gctgcgcgca cccaaggcgc accgccgtcg
    33961 caagcagtac ctggcgcacc gccacgccgt cgcgctggag gcggcggacc tcctcgggcc
    34021 gctggtggag gatctggaag tggtgccgta cgggtacgac gccgacgcgg aggcggcgct
    34081 ggagcgggcc gtggcagcgg ccggcggacg cctgcgcgcc gacatccggt cgaagatcga
    34141 cgagacgcat ccggtgttcc tcggcggccc gtcggccgcc gttcccgccg ttccctccgg
    34201 agcggcccgg tagcgtcggc ccgcgccgtc atgccgtgct gccgtcgtgc ggtggcattc
    34261 agcgcagacc cagcgcgcgg gtgatcgtcg tgaacagctc ggtctggtcg gtgacgcctc
    34321 tgacccgctc ggcgaacggc ccctgggccg cgatacggac ctgggtgccg gtgtgctcct
    34381 gcccgtcctc gggcgtggtg gtcgtggcgt aactgacctt gatccggccg ccctcgtcgg
    34441 tgacgagcgt ggccgacagg cccatcggct ccgcgtcgac cggcacgatc tggctgctgt
    34501 gcccgtggtc ggcggtggtg atcacgaggg tgtcggggtg gcgctcggcg tagtcgcggg
    34561 ccaccttgac ggcccggtcg aacgcggcgg tctcaccgat ctggccgcag gggtccgcct
    34621 cgtggttctg cttgtcgatc gaggcgccct cgacctggag gaagaagccc ttgcccgtcc
    34681 cgccggtccg cgccttggcc tccagcagct cgacggcctt gcgggtctgc gcctccagcg
    34741 tgggagtccc ggccgggcgg cgggggttgg cggtgacgca gcgctgcgcc tcggtgccgc
    34801 cgcgggccgc gggccggccc gtccactcca ccggcacggc cccgggcgcg aacagaccga
    34861 gcaccgggcg ctcgggaccg gccgcgcgca ggccgcgcgc gtcgctcacg atgcggtacc
    34921 ccagcttctc ggcctgctgg gccaccgtga ggccctggta cggcccctcg gtgatcttct
    34981 ggtcgaagcg ctgccggcca ccgccgagca ggacgtcggg ccgcagccgt acggactgtt
    35041 cggcgatcga cccgaggccg ccccggccga tcgtgtcgcg ggggcacccc tccatgtctg
    35101 ccgggccctg gcagtcgcgg tcgccgacgt gcgcggccat cgcggcgggg gtggcgtcgg
    35161 tgagttccgc ggtggtgacc gacccggtgg ccaggccctg gcggcgggcc agttcgagga
    35221 tggtgggcat cgggcggtcg gtgccgggcg tcttggatat acggtagttg acggtcttgt
    35281 ggccggtgga ccaggcggtg gcgctggcgg cggagtcggt gacgtagtcc ggccgtccgt
    35341 ggctgtcgac cgagtaggtg gtgtacgtac cggtctgcgg gaagccgtcc atgtgcagcc
    35401 gtccgcccgc gccgaccgtg tagtcgcggg ccagggtgat ctccgaatcc cccataccgt
    35461 cgccgatcag caggatgacg ttcttcgccg tccggggccg gtgaccggcg ccggcgtcgg
    35521 ccgtggcggt gacgacggtg gtggccgtca cggcgacggc cagggcggcg gccgaccagg
    35581 caagccggcg gcggaagacc tgcgggggca atgacgtcga tctcatcgtg ctggacctcc
    35641 gaaccggcgg aaccgcgcgc ggccccgcca gcgtcatcag ctctagcgga tagaataggc
    35701 agcgagcgta cgccaactaa tcggccaggc gccaacaaga gcgaacaagt acgcacgcga
    35761 acgcgataga gtcgtccgcc ctggcgggca acgacgcccg tccggccgaa tcaccgcagg
    35821 caggaaaagg cgcatgagtg accgcacatc ggcaaccgac caggagggcc gcccgctgct
    35881 gcgcgcgttc gggcagcgcc tcaacgagct gatcgccgct ctgcaccccg acgaacgcaa
    35941 acgccccgga tacgcccggc tcgccaagga gatccgggag accacgggcg gcgccatctc
    36001 cggtacgtac ctctgggagc tggccaccgg caagaagcgc aacgtgaccc tggaacaact
    36061 cgacgtgctc gccgagtact tcggcgtgcc ccccgaatac ttcctcagcg acgacgtggc
    36121 cgaacgggtc aactcccagc tccggctggc cgtggcgctg cgcgacaccc gggtgcgcaa
    36181 cctggcgctg cgcgccgagg gcctgtcacc ggccgcgctg gacgccctgc tgaccatcgt
    36241 cgacgaggcc cgcaaggtgc agaacctggc acccccggag gccggcggcg acggcacgca
    36301 agaaccgccc gccgccgcgc cgtgaccgcc cgggaacggc tcattcccgc ccccggcccg
    36361 cacggcccgt tcgaccgggg ccggttgtcg gcaaagatgt cgcccatgaa cgaagaagta
    36421 ctcaagcttt acccccgcca tacctggacg ccggtcaccg acggcgactc aggcgccttc
    36481 gtccaccacc tcaccggccc cagcgagctg tacgccaaac tcgtccccgc ccggccggac
    36541 accggtctcg acctcaaggc cgaggccgac cgcctggaat ggctcgccgg acagggcgtc
    36601 ccggtgtccc gcgtggtcga tttcggctcc ggggacgccg cgtcctggct gatcaccgag
    36661 gccgtaccgg gtgtctccgc cgccgaggag tggccgtcgg cgcagcgcgc cgaggtggcg
    36721 gaggtgatgg ccgacgtcgc ccggcagctg cacggactgc ccgtcgccga ctgcccgttc
    36781 gacgcgagcc tggacgtgat gatcccgcag gccctgcacc acctcgaagc gggcctggtc
    36841 gacatggacg acctggagga ggagcgggcg ggctggtcgg aaggtcgact tcgcgccgaa
    36901 ctcgaaggca cccgcccgcc ccaggaggac ctggtcgtct gccacggcga tctgtgcccc
    36961 aacaacgtcc tgctcgaccc ggagacccgc cggctgaccg gagtgatcga cgtgggccgc
    37021 ctcggccgcg ccgaccggca cgccgacctg gccctcgcga tgcgcgaact gtcccgcgaa
    37081 gaagacccgt ggttcgggcc gcactgcgtg gagcggttcg tcgagcggta cggcgccgag
    37141 cgcgtggacg ccacgaagac ggcctactac cagctgctgg acgagttctt ctagagccgg
    37201 cggcccgcgc cccacgtccg ggacgcgggc cacggcccgg cgtaagagcc ctgcgcatgc
    37261 gcgcggtcgt gccggccctc agcgggccgg cgcctccggc agcaggtgga agtcctcgaa
    37321 ctggaagccc ggtgagacca cacagctcac cagcacctcc tcgtcggaga ccggacgggc
    37381 gcgctgccag gtgcccgccg gtatcaacac ctggggccgc tgcccgcctg ccaggtcggg
    37441 gcccatgagt acgtccgtgg ggcgggccgc cggccgctcg cccgtaccgc ccagttggaa
    37501 acgcaacggg ccgccccggt gccagaacca cagctccgac gagcgcacgg tgtgccagcg
    37561 cgactcctcc cccgccgaca gcaggaagta gatcgcggag gcggtgggcc ggttcccggc
    37621 gtactcctcg acccgcaagg tcttcccgct gcgccaggtc tccttgtacc agccgccctc
    37681 gggatgtgcc cgcatgccca gcagccgtgc cgtctcgggc tgcttgccgc gggcacccgc
    37741 cgtggccggc gccccgctcg tggccgccgc ccgttccggg gccttcgccg cgccgctccc
    37801 gccgcacgct gtggccgtga cgccgaggac accggccgcc gtcaggccga gggcggcgcg
    37861 gcgcgagagg cctccgcggg gcgaggggtt ttcgcggccg cgcggggccg gagattgctc
    37921 cccgccctgg tggaaagggc acgatctgcc gcactcatcg gtttccatgt caccgtccgt
    37981 ctgtacgggg cgccgtcatg acgcctgacc ggtaggggcc gcccggtgcc gctgctcctc
    38041 ggcgctcagg aacgaggcgg ccagggggga acggaagaag cgcgccagtt gcaggagaaa
    38101 atccagttcc tcggccatgt cgccgccgcc gctctgcggc agcccggacg gccgccccga
    38161 cgtggcggcg cccgagcgct tgttcgccac tgccgcgctg gcccagcacc ccgtcaccgc
    38221 cgcctccacc gaggcgtccg cgacccgggc ggcgcgcacg tgctcgcggg cccgggcgag
    38281 ggtgccctcc ggggagtagt cctccagcgc gagcaggccg tcccggatct cgatggcgcg
    38341 ccggtacagc cgcaggtccg agtggcggac cgcgctcagc aggtcgacgg cgcgcgaacg
    38401 cgggtcggtg agcgtgacgt ccggggtgac gcgtacgagc gtccgccaca gtggatggag
    38461 ccggtacatg accgccatgt cccgcgcggt gcgccacggc cggcgcagca gcggcagcgc
    38521 ggcacccgcc gccatgaacg ccgcctccgc cccggagatg gcgggaaaaa ggtgcggaat
    38581 cgtggcatcg cggctgagca catggaccag tgacagcgcc atgagcaccg cggacagggc
    38641 gattccggtt ccgaacagca gcagtccggc ccgggtgggc gtgttcttca cctgccgccc
    38701 gcacgcccag cacgcggcga cacaggccgt gttcgccacc aggtggtagc cgagcaggac
    38761 gacccagtag tacgtgtccg ggctcgcctc ctggccgggc ccgctgggga ccacgtgccg
    38821 ggtgtgcggc ggcgagagga cgcacagcgt gacgagcgcg gccagcgtca ggaccgccgc
    38881 ggccaggatg gccagctggg tccgccgcag gccgacgatc gccgagatga actcgaacac
    38941 ggcggtggcg gccaggagtc cgacgatctc cttggccagg aacacggtgt gcgggtccag
    39001 caccgccgtc gcgacggacg agacctgcgg cagctggagg gtcatcgcca ccgaggccag
    39061 acccaccgcg agccacaggg gccgctgctg cggcgtccgg accgcgacgg gtgcccgcag
    39121 cagggtgacg acccacatca gcgcgaggcc cagccactcc agttggacga acaggccgtg
    39181 cggcccccgg tcagtcatgg gtgatgccca gggcccggtc ggcgcggtcc gtggtggcgc
    39241 accgctgcgg cccccggccc ggacccgtgg catgcgtcct gatcaggctc gccagcattt
    39301 ccgcctcctg ctcctgacgc gtcgagtaat tggtgcgggc gagcatccgc tggatgagac
    39361 ggggactgag gtcggccagc accgaactga taccgccgga atttccgtcc gccagcatct
    39421 ggtggtcgaa gagcaggtgc ccgatctcgt gcagcacgat gtgttcctgg tgcagcggcg
    39481 cggtacgggc ctcgaagaag atgtggtcgt ccgtgtcggt ggccagccac agtccgcacg
    39541 ccgccatttt cgcgacgtgc gtgggcaggg cgtgcagatg cagcggacgc tgtcgctgct
    39601 cggaaatgct ccggcagaat tcctcgacgg aaaagggagt cggcaaagtg atgtcggtca
    39661 gtttcgcccg gcaccgccgg cgcaatgtgg agtacccgta cagcatgtgg gagaactgcc
    39721 atttcttctg tgaggggcag cgcattcttg cgcgcgctgc cccgtgctcc gacggctggt
    39781 agcacgatgc ggacccaccc ggcccgggcg cggtccggcg ggggtgtgcg gggagaggcc
    39841 gggaggcgtc agcgcggagg tccccgcagc gcgtccgggg agccgcccca gtagaccgtg
    39901 cgtcgcagct ccgccgtcgg tgcttgcgcg ccggccgcgg gggcggcgtc gccggacagc
    39961 ccgcggcgcg ggaggagcag ggagcgggta aacgtttttt cgcggcgtgg tgcgcacgcc
    40021 gggccgaacg tcccggggcc gtgcggacag cgggcggcgc ggcggccgcc ggacatccgg
    40081 aacatccggg agccgttcgg acaacaggcg gcccggcgtg cgtcgcagcg gaacggtacg
    40141 ccggaagtgt ccgtgaccga aggggcgtgc gtcggcggga cgctcatcgg cgacccgtcc
    40201 ggaagcggag tgaccgccga ggcgggctcc cgcgataacc gatggcggcc ctcggaacgc
    40261 gccacctcgc tgtcgctcat gcgtcgccct tctcgatctc cgccagggaa ttgctccctc
    40321 cgctggagcg gacgactgtc acggtacggc gtcgctgaac cggacgccac ggtttggcgc
    40381 atttcgagcc aacccgctgg ccgaatatgc ctctatcacc tgccctcggc gaagacgcac
    40441 ccaggggcgc ggcgctgcgc cccgaacggc ccgcatcggg ccgcattcgc ttcccgccga
    40501 catgcccgcc acggtcggct ccgcccccgc cgaggaacgc acaccgcccg aacgctccgg
    40561 cgctccggcg acgtacgacc gacccgtccg caccccgccc cgccgacccc gacgagacca
    40621 ccggcgagac gcgccccacc gaaacggccc gcgaccggcc gtacggcggg tgttcgcgga
    40681 cgcccgtcag cacgcttcac accctggccg gagaccgggg cctccgcacc gttcccagcg
    40741 ggccgcacac ccctcctccc gccgacaacc cccgccaccc cagggcctgt cgggccttgg
    40801 acacgccgaa ctccctgctc acagcgtcgg ccaccaccaa ggcggccccg acgaccgccc
    40861 gactcccgca cgggcgcgca ccacctcttg gacgcggtat gcagccgcca actcgacacg
    40921 gacccatccg ccccgggccc ggtcacccag aaactgacat gccatcaact tgagtaccgc
    40981 cacacgacca gacatccccg ccagtgcggc cgactccccc cggacacccg gcacctccca
    41041 ccggacgcac accgcgccat cccaccctct cccccaccac atcgacgcac cggccgccac
    41101 cccgacgacc cgtcaccttc actcacgccg ccgctccgcg ccgacggaag acggacccga
    41161 cagcgcttca cagccaccca ttccgaagtc cgccgccccg aagcgccatt cgtggtaaag
    41221 gggaggaacc gaccgtacgc ggccaccgcc ctgaccacac cggcagcgaa aaccagccac
    41281 cggcgcacgg tcggcgcgac cgagagccga ccgccctgaa ccggtcacgc gatgcggccg
    41341 gaacccgtca tgcgatgcga ctgggccccg tcacgcgatg cggccgggac cggtcacacg
    41401 atgcggctcg accgcccctc ccgaaccccc cggcactcac ccccgaagat ccctgcaaac
    41461 ctccacacac ctccacgcat ctcgcgcatc tccacccgtc tccacgcatc tccgcacacc
    41521 ccagatcccc caacggccgc cgccgcccca cccgttgacg ggttggtcca gaccttttag
    41581 ggtgcgactg ccatacggca cccggcggca ccggttccgc aacctggcgc gcggccgggg
    41641 atgcgcactt tcggttctca caccctgtac cacccacact cacaggggtg ccccatgaaa
    41701 gaccggcgca gattccgcag cagactccgt ggcagcgccg cggccctgct caccacgctc
    41761 atcctgtccg tggccgccgt gctgaccggc ccggcggccc ccgcccaggc cgcgggaacc
    41821 ctcaccgcgg ccttctccac ccaggacaac ggcccctggt ggaagggcac ctacgtcgtc
    41881 cgcaacagcg ggtccgccgc cgtcaccggc tggaccctgg agttcgacct gccggccggt
    41941 gtcaccgtca gcgggcacta ctacggcgac gccaccgtga acggtcgcca tgtgacggtc
    42001 aagaacgccc actacaacgc gaccgttccg gccggcggca gcaccgaacc gttcagctac
    42061 tggttcgtcg ccaacggccc cgtcggcacc cccacggcct gcaccgtcaa cggtgacaag
    42121 tgcgacggca gcccggacgt gccaccgtcc gcgcccggca cgccccaggt caccggcacc
    42181 accgcgcgca gcgtcgcact gagctggccg gccgcctcgc cgggtgacca cccggtcacc
    42241 tcctacgagg tgctcagcga gggccgcccg gtcgccaccg ccaccggcac caccgcgacc
    42301 gtcaccggcc tgaccccggc cacccggtac accttcaccg tccgggccaa ggacaggcgc
    42361 ggcaacaccg gtccgccgag cgcgccggtg accgcggaca ccgtggaccc ggcgagcgac
    42421 cccgtaccgc cgaccgcgcc gcgcgctctg cgcagcaccg cggtcaccgc ctccagcgtc
    42481 tccctggcct gggaccgggc caccgacaac gtcggcgtgg tcgcgtacga cgtgtaccgg
    42541 ggcgccgacc tggtcaccac ggttcccggc agcaccaccg ccgccacggt cgacggcctg
    42601 acgcctgcca ccacgtaccg tttctccgtc acggcgcgcg acgccgccga gaacgcctcc
    42661 cccgcctccg acgccctgac cgtcaccacg gacgacgtgg ccgggcccgg caagtacctg
    42721 aaggtcggct acttcgcgca gtggggcatc tacggacgcc agtacttcgt caagaacctg
    42781 gacacctcgg gagccgccgc cgacctggac gtcgtcaact acgccttcgc caacatcgac
    42841 cccaagaatc tcacctgtct ggcgggtgtg accaagggcg tctccggcaa tccgcaggac
    42901 ccggacgagg gcaccggcgc gggcgacgcg gacgccgact acgggcgcgc cttccctgcc
    42961 gcgcagtcgg tcgacggagt ggccgacgac ggctggggca agctgcgcgg caacctcaac
    43021 cagctcaaga agctgaaggc caagcatccg catctgaagg tggtgatgtc cctcggcggc
    43081 tggacgtact cgaagttctt ctccgacgcc gcggccaccg acgcctcccg caagaagttc
    43141 gccgcctcct gcatcgacat ctggatcaag ggcaacctgc ccgtctacaa cggcgcgggc
    43201 ggccccggga ccggagcggg catcttcgac ggaatcgacc tggactggga gtggccggga
    43261 gccgaaggcc accccggcaa ccactacagc ccggacgaca aggccaacct cgcgctgctg
    43321 atcaaggagt tccgccggca gctcgacgcg ctgggcggcc cgcacaagct gctgacggcc
    43381 ttcaccccgg ccgaccccgt caagatccag cagggctggg acctggcctc gatcttcacg
    43441 tcgctggact acgccaacgt ccagggctac gacttccacg gctccggcag cgacaactcc
    43501 tgggaaccca agcgcaccgg ccaccaggcc aacctgtacc gcgacaccca ggacccgtac
    43561 gacttccact tcagcgtcga gaacgccgtc aaggcgtaca ccgacgcggg agtcagcccg
    43621 cgcaagctga ccatcggctt cccgttctac ggccgtggct ggaagaccgt cgcggacggc
    43681 ggggcgcacg gcgaatggca gtcggcggac ggcgcggccc ccggccagtt ccccgaggaa
    43741 gccggcatcc ggggctacca gaacatgctg accaacgtcc ccgacatgac cgtccaccac
    43801 gacgaacagt ccatctcgac gtacgggtac accggcgcga acggtcagtg gtggtccttc
    43861 gacgacacct ggtcaatcgg aaagaagacg gactgggtca agtccaaagg gcttctgggc
    43921 gccatgatct gggagatgtc cggcgacact ccgacaggca cgctgatgaa ggccatcaag
    43981 aacgggctcg cggggcggcc cggagccgcg cccaccggct agccacgcac ggtcgccccc
    44041 gccaccgcgg ccggtgacca ccagcgagca ccgccgcaga aaccaccagg tcaccgcggc
    44101 gcggcagcag cggacgcggg ctcgccgccg cggcccggcc cgcactccgc gagccgggcc
    44161 gcggcaccgg gcccgccccc cgcccggcac cgcccccagc gaccgacagg cacggattgc
    44221 tcacagcgaa gaggcgacgc ggtttctcac gcagcgatgt cggctgcgag ccggtcggca
    44281 gcgctgcggg gctctcggcc gaggagttgg gccagcaagg ggtcggcctc cgcgaagtag
    44341 ccggcgcggc tggcctggta ccaggtgagc atgaaccggg ccgctcgctc tggaacacca
    44401 gtcatgagct ggtcggcgac ccactgctcg tcgtccagga cggtgcgctt gacggtgcgg
    44461 cctgtgagat cagaggcgat cgtggcgaga tcgtcgaagg tgacggcggt gggtgcagtg
    44521 agggtgacgg ggccttcgaa ggagcggtca ccggtgagga tgaccgcgac ggcctcggcc
    44581 acgtcatcgc ggtcggtgta ggggaccggg ccgtccgccg gctgggcgat ctcgccggtg
    44641 cgtcgccacg ggccgagcac ctggtcgagt gggccgtagg cgccgttgcg cagtgcggtc
    44701 caggcaacgc cgcagtccgc gagaatggcc tcggtggcgc ggtggatgtc tgaggccggg
    44761 tacgggttgc cggggatggc gccgtgctgg ctcgtgtaga ggattcgccg ggcaccggcc
    44821 gcgacggcgg cgtcgatggc attgcggtgc aggtggacca ggtcggcggt cggatcgttg
    44881 ccggacacca gaagcacctg atcggcgccg gcgaaggagc cgcgcagcac ggccggttcc
    44941 tcgtacgagc cctgccgtac gcgcacaccc cggtcggcga ggtgctgcgc cttggccacc
    45001 tcgcggacgc tgacgccgat ctggtcggcg ggcacgcgct ggaggaggtg ctcgacggtg
    45061 gcgccgccca gcccgccggt ggcaccggtg acaacgatca tgttcctggc ctcttcctga
    45121 ttacccgcag ggtccggttc ggagggacgg agagcctcaa gttgaccatg gtggtcagtt
    45181 tctgcctgtt tacgacagta ggtaaactga ccccatgggt caaattgagt cggcgggagc
    45241 cggtgcctcg ggcggcgccg caccttccgc atcccggctg cgcgccgatg ccaggcgcaa
    45301 ctccgagcag atccgcgccg ccgcgatcgg cgccttccag gggcggggcc tgaccgtgcc
    45361 gctggaggat gtcgccaaag cggcaggggt cagcaaggcc acgatcttca accggttcgg
    45421 cgggcggatc ggcctcatcg aggccgtcat cgaggaagtc gtcgccacgg aactgttcgc
    45481 cgtcatcgac cgcgcccgga ccatcgccga cgccggcgag cgaaccgcgt attacctcac
    45541 cgcgctccgc gatctgcagt accgccagcc cgccgtcaac gacgtcctgc tgcagaccta
    45601 tccgcactca cagcagctca tggagatctg ccgagcggga agcgaggcca acaccgaaat
    45661 cgtcgcggcc gcgcgggccg gcggcgcagt gcggccggag ttcacggcgg gcgacctcca
    45721 cgcgctcgtc gtcgacaccg ccctcgccct caagcacgga cagcggcctc cccgggacga
    45781 gtacgaccgc cgcaccacat acctcttgga cggaatccgc ggaccccggc ccacgcttgg
    45841 ctgaccgatg gaccggctgg cccgcgccca cagttcctcc cgcgccgcgc ccttgatccc
    45901 gaccgggcgc ccggttgctc gccgacacgg ctcgggcgga acgtcaccgc cgaggcagcg
    45961 tccacgccgg gcagcacatg ctggtgcttt ccgggatcag tcgcgcgacc ggtccgggaa
    46021 ggtcggcggc gccgccaggg tccatgacgc caacaggctc agcgcctggg cggatgccga
    46081 ttcgggttcg gcggtgtaga ggaacagggt ggtctcgctg tccccgggca gtgcgagagt
    46141 ctcgtactcc acggtgagtt cgccgaccaa ggggtgccgc agccgcttgg agccgtgggt
    46201 gcgctggtgc acgcggtgct gctgccacca gcggtcgaag tcgtcgctca gtccccgcag
    46261 ctcggcgacg agcgcctccg tggcctgccg ctccgatgcg cgggccgcgt ccaggcgcag
    46321 gttctccacc gcggcgcggg cctgcacttc ccagtcgacg aacaggtcgc gcgcgccgtg
    46381 gtcgaggaag agccagcggg tgtagttgcg ttcagtggcc ggcatggcgt cgaagtcggc
    46441 gaacagggct ctggccatcc ggttcgcccc caggactgcg gatcgacgcc ccaggatgag
    46501 ggcgggaagg gcatggtcca gggagtcgag gagccggtgg agtccggggc gcaggcgttg
    46561 gacgccgggc gtacgtgccg gagggcgggt ggcggtgaca ccgacgaggt tcttgagatg
    46621 ggcaagacct gcctcgtcca gccgcagggc gtgcccgatg gcttcgacga cggcagggga
    46681 cggattgatg gggcggccct gctcaagtcg ggcgtagtag tcggcggaga cccccgcgag
    46741 gagggcgacc tcctctcgcc ggagtcccgg tacgcgccgc acccgtccgt ccggtggcag
    46801 ccccgcccgt tcggggtcgc actgggcacg ggagcgcctg aggaagtcgg cgatttcacg
    46861 gttgacggaa gccatgggaa caagtctgtg gcacgaaatg cgctgatggc cgcccaagct
    46921 gggtctctca gtcctagtca gccgcggcct agggcgcaca gggcgtggca tggccccgaa
    46981 agccgctccc ccgcggcaca ggcttgagtc agcgccggac cagcagccct ggtccggctt
    47041 cccgtcccga acgtacgaaa gaggaacact catgtctgcc accaccgtcc ccgccacctg
    47101 gttcgtcacc ggcgcctccc gcggactcgg gctggagctg gtccggcagt tgctcgccca
    47161 gggcgacaac gtggccgcca ccacccgctc ccccgaacgc ctcacgaccg cgctcggcgg
    47221 cgcggccgac accggccggc tcctcgcgct gaacgtcgac ctgacggacg aggcgcaggt
    47281 ccagcacgcc gtggaccgga ccaccgagcg gttcggccgc cttgacgtcg tcgtgaacaa
    47341 cgccggttac ggctacctcg ccgccgtcga ggagaccagc gccaaggacg tgcgggacat
    47401 gctcgacgtc caggtcgtcg gcgtctggaa cgtgctgcgc gcggcactgc cggtcttgcg
    47461 tgagcagcgc gcgggccgtg tcatcaacat ctcctcgatc ctgggtctga ccacgatgcc
    47521 cggctgggcc ctgtactgcg cgggcaagtt cgccctcgaa gggctgagcg aggcgctcgc
    47581 cgccgaggtc gcggacttcg gcatcaaggt caccgtcgtg gagcccggct acttccgcac
    47641 ttccttcctc accacggagt cgctggccct gcccgccgag acctcggagc actacccggc
    47701 cgtgcgggcc atggtcgacg accacctcaa gctccagggg cgccagctcg gcgacccggt
    47761 caagggagcc gccgccatca tcgagcgcgc cggcctcgac gacggtcccc tgcgccagct
    47821 gctgggctcc gacgcccacg cctacgccac cgcgaaggtc gacgccctgc gcgccgacct
    47881 cgacgcgact gcggcctccg cagcgatcac ggatttcccc gaggcctgag cacgcgccgc
    47941 gaccagccga tcgctatagc caaccgcttt agttataggc taaaactaaa gcgtgtagcg
    48001 ataacggcga atgtcttcgc cgcctcatct gaaggggtct cgacatgacc gcgacaccgg
    48061 gtgcactcca caccgttctg ggagccggcc ccacgggcac ctccggcgtc ctggaactgg
    48121 cgcgccgcgg gcatgcggtc cggctggtcg accgttccga ttccggtga
//
