LOCUS       BGC0000716             29606 bp    DNA     linear   BCT 26-JUL-1999
DEFINITION  Streptomyces flavopersicus spectinomycin biosynthesis gene cluster,
            complete sequence.
ACCESSION   BGC0000716
VERSION     BGC0000716
KEYWORDS    .
SOURCE      Streptomyces netropsis
  ORGANISM  Streptomyces netropsis
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
COMMENT     On Jul 26, 1999 this sequence version replaced U70376.1.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 14:05:48
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 29606
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..29606
                     /db_xref="taxon:55404"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces netropsis"
                     /strain="NRRL 2820"
                     /type_material="type strain of Streptomyces flavopersicus"
     subregion       1..29606
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="saccharide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..29606
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     repeat_region   380..413
                     /rpt_family="IS1374"
                     /rpt_type=inverted
     repeat_region   380..1774
                     /rpt_family="IS1374"
                     /rpt_type=dispersed
     gene            436..1608
                     /gene="insA"
     CDS             436..1608
                     /codon_start=1
                     /gene="insA"
                     /note="putative transposase; transposase of IS1374"
                     /product="InsA"
                     /protein_id="AAD45539.1"
                     /transl_table=11
                     /translation="MGGVLASARLWDGELSVVHERFVHRFNREEPRQSALAYMRGLTAP
                     LERKNGWTLAEEAGHAGPDRIHRLLNRIEWDADEVLGDVRDYVVEHLGDRNAILIIDDT
                     GFLKKGTRSAGVQRQYSGTAGRTENSQIGVFLAYATRRGRTLIDRRLYLPMSWTGDRDR
                     CRQAGTDDSVTFETKVAMAKAMVRRAIRDRIPFGWVTADAAYGYSKGWRFELEQADVFH
                     VMATTRHDTVVTRWSIDHPVHDLPRQKWKRRSCGPGAHGPRVYDWARVEVRPWHREDRR
                     HWVIARRSVRRPEEISYYVAYCPTETTLDELISVAGSRWAVEDCFQSAKQECGLDDYQV
                     RRYPGWHRHMTLAMAAHACLTVLQARELDTEKAETDPPSSSPSAFPRSDA"
     repeat_region   1741..1774
                     /rpt_family="IS1374"
                     /rpt_type=inverted
     CDS             complement(2696..3466)
                     /codon_start=1
                     /note="homolog to streptomycin-6-phosphate phosphatase
                     StrK; orf1; The protein is most likely inactive due to DNA
                     rearrangements at the N- and C-terminal regions of the
                     gene"
                     /product="streptomycin-6-phosphate phosphatase"
                     /protein_id="AAD45540.1"
                     /transl_table=11
                     /translation="MTAAFPDRRGGGPVHAVRQGKRRVRRWGAVTGVLLTSVTVSSAAP
                     PSGPVSGDFRPSPARNVILLIGDGMGDSEITAARNYAVAAEGRLTMDRLPMTGSSLTSA
                     VDERGHPDYVTDSAAGATAWATGRKTVNGRISRTPDTNEPLPTLLELARREGYATGNVT
                     TAQLTDATPAALTAHVTDRSCKGPADMAACPADTWARGGRGSIAEQTPAGPERGGCSGA
                     SLQVSRCSSCRRRTLFERSPHGLCTYDRWATRRN"
     gene            3618..4541
                     /gene="aph(6)"
     CDS             3618..4541
                     /codon_start=1
                     /gene="aph_6_"
                     /note="aminoglycoside phosphotransferase; low level
                     streptomycin resistance"
                     /product="APH(6)"
                     /protein_id="AAD45541.1"
                     /transl_table=11
                     /translation="MDTSKAIEVPEHLAASYSRGFGEEGRAWIAALPTLAAAFLDRWEL
                     RRDGAARAGEASLVLPVLRQDGTRAVLKLQMPREETTAALIGLCTWNGAGTVRLLDHDP
                     HSSTMLLERLDSARTLASLEDDDVAMGILAELLARLVSVPAPRELRRLKDIAADMLERV
                     PRAVTALADPADRQLLRGWAAAVAELIEEPGDQMLHWDLHYDNVLAAEREPWLAIDPEP
                     LAGDPGFDLWPALDSRWDDIVATGDTRRVVRRRFDLLTGVLGLDRGRAAGWTLGRLLQN
                     ELWDIEGGGSALAPSSVAMAEALQNR"
     CDS             4949..5263
                     /codon_start=1
                     /note="homolog to amidinotransferase; corresponding gene is
                     deleted at its C-terminus"
                     /product="Orf2"
                     /protein_id="AAD45542.1"
                     /transl_table=11
                     /translation="MRSVMSLVSVHNEWDPLEEIIVGTAAGARVPRADRSVFAVEYAGE
                     YDSQDQVPSGPYPDRVLKETEEELHVLCEELTKLGVTVRRPQQRDNSALTRSSKGNDHG
                     "
     CDS             complement(5116..5388)
                     /codon_start=1
                     /note="homolog to IS112 transposase; corresponding gene is
                     deleted at its C-terminal end"
                     /product="orf3"
                     /protein_id="AAB66653.1"
                     /transl_table=11
                     /translation="MAGVITASEPSWIAPFTGLSPRHFRKVVTLLRREGADTPRRGHPW
                     SLPLEERVRAELSRCCGRRTVTPSFVSSSHRTWSSSSVSLRTRSG"
     gene            6305..7297
                     /gene="spcR"
     CDS             6305..7297
                     /codon_start=1
                     /gene="spcR"
                     /note="putative transcriptional regulator of spectinomycin
                     biosynthesis"
                     /product="SpcR"
                     /protein_id="AAB66654.1"
                     /transl_table=11
                     /translation="MTTVKGACVSVPISKLLLADSPRSRAVDSSHVELLAQLEEVLPPI
                     TVHRDSMRVVDGVHRLEAAKARGATEINVVFFEGTLEDAFAHAVEKNVRHGLPLTLQER
                     TDAAARIMASHADWSDRRVAATAGLSRKAVAAIRRMSADGRAGEAVRTGRDGRVRPVSS
                     AAGREHAARVLRENPGASLREVARVAGISPSTVRDVRNRTASGEDPVPVRQRPPDRRPP
                     VPGPATPGTVRLAAAREQRMADCSRRYANLLHGLKSDPSVRLTESGRLVLRLLETRLIL
                     IGERDRLLQAIPQHCVPNLSAAVRQCAEAWDEFAQHLETFEAAEELGAG"
     gene            complement(7526..8518)
                     /gene="spcN"
     CDS             complement(7526..8518)
                     /codon_start=1
                     /gene="spcN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /note="spectinomycin phosphotransferase; spectinomycin
                     resistance protein"
                     /product="SpcN"
                     /protein_id="AAB66655.1"
                     /sec_met_domain="APH (E-value: 2.1e-17, bitscore: 54.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDLPENLDQESLFQGLREFGISTTSASYAPLGFGDYHWHITGDD
                     GQRWFATVSDLEHKEHCGHGAPAALRGLRRAMDTAVHLREQGGLPFVVAPRTTSDGASL
                     VPLDSRYALTVFPHVSARPGEFGQKLTERERDQVLVLLAELHGQAPPKCTPTTDMVPTG
                     LDGVHTALAEPSGTWTGGPFSEPARELLAEHEATLRGRMAEFGELVARVRGRGAPLVVT
                     HGEPHPGNLILGEDGYVLVDWDTVGLAIPERDLSLISDDPAALARYTELTGHTPDPAAL
                     ALYRLRWSLLDVAEFVEWFRGEHQRTSDTEAAWQSFAETLDHLNSEVPS"
     gene            complement(8528..9829)
                     /gene="spcT"
     CDS             complement(8528..9829)
                     /codon_start=1
                     /gene="spcT"
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 322.8; E-value: 4.9e-98)"
                     /gene_kind="transport"
                     /note="putative transport protein; putative export protein
                     for spectinomycin"
                     /product="SpcT"
                     /protein_id="AAD45543.1"
                     /transl_table=11
                     /translation="MPERPSTADLNANAPDARDLDRGYRHGYRLFLGSHALNETGAAAT
                     LVVLPLTAVLSLDAQAWQTALIQTFHFAPYLVFGLPAGAVVERLRPRRVMIGADLLRFV
                     ALMSLPVAWALNALSLPHLYAVALLLGGAQLFGDIADQSYLPHLLVKDRLFQGNSNLQM
                     IRATAELGGPGIGGVAVQWLGTHLAVAVNGLASALSALLLWRIPVPDAQPAAPSHGLVR
                     QTWHGISVLLRHPVLRLLALSASLNNLILSAALALDVVFLNQVVGVTAGLVGFLLAAGA
                     VGALIGAWLAPRLTRALGSGRTAVLAVPVAAPFMFLIPLTGDGWRVALFALGHIAISIG
                     ITVFNIMQVTYRQQVCPPELLSRMAAMFRWAVWGAAPLGATAGGALAASVGVRDTLWIL
                     AGALMVVAPLLLCSPLRRMRDFDENPSVGTLKRC"
     gene            complement(9900..10700)
                     /gene="spcA"
     CDS             complement(9900..10700)
                     /codon_start=1
                     /gene="spcA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1207:inositol monophosphatase (Score: 231.5; E-value:
                     2.3e-70)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative myo-inositol monophosphatase"
                     /product="SpcA"
                     /protein_id="AAD45544.1"
                     /transl_table=11
                     /translation="MVSSHSAFDSGELTELAVTAAREAGQILLRGAEEGPVRASAKSSR
                     TDLVTVFDRRSEDHIVGLLTAHRPDDGVLGEEGGERPGTSGVRWVIDPLDGTANYVARY
                     PAFVVSVAAELDGVGVVGVVHDPSRQETFSAERGRGARLNGRALHVPHAADGLAEVLLS
                     TGFSSDLAVRARQAALAARIACRVRDVRSSGSAALDLCWVAGGRLGAYYESDTRHWDRA
                     AGALIASEAGAWVGDLDGGPASDRMVIACTPGVEQGLRTLLGHA"
     gene            10815..11993
                     /gene="spcB"
     CDS             10815..11993
                     /codon_start=1
                     /gene="spcB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 201.1; E-value: 5e-61)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative myo-inositol dehydrogenase"
                     /product="SpcB"
                     /protein_id="AAD45545.1"
                     /transl_table=11
                     /translation="MAMVPPPITLDVLVGAVSETQRIRIGVIGCGTVAQIMHLPYLRSL
                     PAQFEIFALSDLSPGLLDLLGERYGVPATRRFLDYRGLLESEVDAVLVLSAGSHAPQVL
                     AAAEAGKHILVEKPLCFTLREADEIAAAVSRSQVRLMVAYMKRFDPGFRHGERLVHAMR
                     EPRYVQINTLHPSEDQYIDIHGVHRFGDIPRDVAQRAEKAQEELLDEAVGAVSSALRFV
                     YHDVFLGSMVHDINALRSLVGEPAGVLFTDIWPPDSKFPSVTTVLRHAGNLRTTYTWTY
                     LAEVRDYFEELAVFSSSERVRVQFPSPFLKHWPTPVVAQRMEHGALVEERVEVSHAEAF
                     REELLAFHECVVSGSQPLTDTADARTDIAVLQQIFAAFDPAGLGGEAKTSRG"
     gene            12020..13345
                     /gene="spcC"
     CDS             12020..13345
                     /NRPS_PKS="Domain: Aminotran_3 (35-373). E-value: 3.1e-89.
                     Score: 291.1. Matches aSDomain:
                     nrpspksdomains_spcC_Aminotran_3.1"
                     /codon_start=1
                     /gene="spcC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 382.2;
                     E-value: 4.8e-116)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative aminotransferase"
                     /product="SpcC"
                     /protein_id="AAD45546.1"
                     /sec_met_domain="Aminotran_3 (E-value: 2.7e-96, bitscore:
                     313.1, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHSVTLPSTKDIIELERRHRLPGGQSMTDLAGIVVDRAVNAEVW
                     DRDGKRYIDFFTGVGVSNIGHSHPAFLEELTTQLSRCAVGTFYTDVRSRYFALLAAQLP
                     EQLGEIHMFSTGSEAVEAAVKLARAATGKHEIVSFWGGFHGKTQGALSLHGGPRKHRSG
                     PFPPGSHQVPYADCHHCPLQLEHPECGQRCVDLAEQSIENGSVGDLAAVIVEPVQGTNG
                     NIIPPEGYLRTLRQLADRHGALLILDEVITGFGRTGALFAFEHDPGIAPDVVVLGKAMA
                     SGVPASAIVSRSGLVEGTSFAVPSAAASTFGGNPLASAASLATLRVLLDERLPERSHEL
                     GKSVSDRLSAWREEFPFVGNADNIGLMIGVELVDPATRLPLPKGITRRLFQELMARGVL
                     AMAYDSRIRLYPPLSIPTHHLEEGLAAFEGAFRAMAPAISRL"
     aSDomain        12125..13138
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spcC_Aminotran_3.1"
                     /evalue="3.10E-89"
                     /label="spcC_Aminotran_3.1"
                     /locus_tag="spcC"
                     /protein_end="373"
                     /protein_start="35"
                     /score="291.1"
                     /tool="antismash"
                     /translation="VDRAVNAEVWDRDGKRYIDFFTGVGVSNIGHSHPAFLEELTTQLS
                     RCAVGTFYTDVRSRYFALLAAQLPEQLGEIHMFSTGSEAVEAAVKLARAATGKHEIVSF
                     WGGFHGKTQGALSLHGGPRKHRSGPFPPGSHQVPYADCHHCPLQLEHPECGQRCVDLAE
                     QSIENGSVGDLAAVIVEPVQGTNGNIIPPEGYLRTLRQLADRHGALLILDEVITGFGRT
                     GALFAFEHDPGIAPDVVVLGKAMASGVPASAIVSRSGLVEGTSFAVPSAAASTFGGNPL
                     ASAASLATLRVLLDERLPERSHELGKSVSDRLSAWREEFPFVGNADNIGLMIGVELV"
     gene            13372..14160
                     /gene="spcD"
     CDS             13372..14160
                     /codon_start=1
                     /gene="spcD"
                     /note="putative epimerase"
                     /product="SpcD"
                     /protein_id="AAD45547.1"
                     /transl_table=11
                     /translation="MELGCVVRSAEEAEHAAGLPFDYGELKGDMLCVPPDDLAALTARL
                     HSVRLPFKAMTSPLPRRYGCRVVGPEADHTGALKVFRDMCDRGAALGVCTVVLGSGQAR
                     HVPPGFPAQDADRQLRDFLLAASDVCAERDMTLALEHLNRTETNLVNSCTEARAVIDAL
                     EAPGVRITADCFHLISEGLDIRTEVAVAGGSIAHAHTSAVPRGSGDFREEAQREFVSAL
                     RAAGYDGGLTVEDEFRDFGREAGEAAILFHRVIEEANVLL"
     gene            14258..15451
                     /gene="spcX"
     CDS             14258..15451
                     /codon_start=1
                     /gene="spcX"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143:sugar-binding lipoprotein (Score: 212.4; E-value:
                     2.3e-64)"
                     /gene_kind="biosynthetic-additional"
                     /note="homolog to multiple sugar binding protein"
                     /product="SpcX"
                     /protein_id="AAD45548.1"
                     /transl_table=11
                     /translation="MALTFLTDHTAPLMRGLADRVVADWHERHPETPVELAVLDHEELR
                     DELPARLTGAPSADIMTWFAGNRMDALAGKDLMLNISAMWKAEGFDAVYLPRFRNMTGG
                     MGPSYFLPTSHYWWAVYYRPSVFAAAGITGTPTTWDELTAACRALKSSGITPFALGARY
                     RCPAAAWFDYLNMRLNGPDVHDALMRLRIPYTDDRIRRVFAFWRELIEQEFFLGDPGDY
                     DEEEAVAAVLRGEAGMTLTGAYATDEYTPQGEPDIDFFRFPVIDPTLPIGEDTPVDGYF
                     VPANTDSPEEATRFLAYLGSRHVQQVTIERLSTLPTRTDVDTEKGGRHVAKGMRILQGA
                     DHLSQFYDLDTPWELANVGMSAFVSFTQDPARGEELLRELESARQGQLRRRGPATPR"
     gene            15508..16791
                     /gene="spcE"
     CDS             15508..16791
                     /NRPS_PKS="Domain: Aminotran_1_2 (32-157). E-value: 1e-10.
                     Score: 33.1. Matches aSDomain:
                     nrpspksdomains_spcE_Aminotran_1_2.1"
                     /codon_start=1
                     /gene="spcE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     351; E-value: 1.4e-106)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative aminotransferase"
                     /product="SpcE"
                     /protein_id="AAD45549.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4e-11, bitscore:
                     33.1, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.9e-94,
                     bitscore: 307.3, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTPIRSSPLALHGGAPVHHGAWPVWPQAPESTLTLLKEAATSGRW
                     AISGAYTGTPSFERRFADAFAAYHQVPYAVPTTNGSAALTIAMEALGAGPGTEVIVPGL
                     TWVACASSAAALGATPVLVDVDPETLSISADAAKAAVTDRTVAILVVHAYCSSADIDAF
                     LELSRSTGIPLIEDCSQAHGAEWNGRKVGTYGTIGVFSLQQTKVLTSGEGGIAITSDDD
                     LYDRLQQYRANGRRWGARPVLHQLELEDVGTYEGHNHAMSEFHAAVALSQLDHLDAQSA
                     LRSTNAEVLNGLLERIPGVSTVPAPAGLTRRTYYDYVIRLDPDLLGAVPIDRVVDAMAA
                     ELGMFFETLDAPLNANKLYGPLKSPRTPPSEAVREKLDPARFPLPAATAAFHTCFAFLH
                     QALLATPEERGGDRHRRREGGAEHRSAP"
     aSDomain        15604..15978
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spcE_Aminotran_1_2.1"
                     /evalue="1.00E-10"
                     /label="spcE_Aminotran_1_2.1"
                     /locus_tag="spcE"
                     /protein_end="157"
                     /protein_start="32"
                     /score="33.1"
                     /tool="antismash"
                     /translation="LTLLKEAATSGRWAISGAYTGTPSFERRFADAFAAYHQVPYAVPT
                     TNGSAALTIAMEALGAGPGTEVIVPGLTWVACASSAAALGATPVLVDVDPETLSISADA
                     AKAAVTDRTVAILVVHAYCSS"
     gene            16813..17721
                     /gene="spcY"
     CDS             16813..17721
                     /codon_start=1
                     /gene="spcY"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /note="homolog to molybdene cofactor synthesis protein"
                     /product="SpcY"
                     /protein_id="AAD45550.1"
                     /sec_met_domain="Fer4_12 (E-value: 1.7e-09, bitscore: 28.6,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVHVEHGKVINPEGVEINASLQCNMRCKSCAHLSPLFRKENADP
                     AETHDILTLLARNYHASYAKIMGGEPLLHPDIVGLIEAVRTSRVADTVLVATNGTLLDR
                     ASEEFWRAVDSLEISVYPSRPLTSEQIDRYHGMAREYDVSLLINHYGHFREIYSETGAD
                     SPELVQDVYDTCKLAHYWRSHTVYDGWLYRCPQSLFVPQQLENGGWDPREDGIEIADDP
                     GFLERLHRFLTRTTPLRACGNCLGSVGRLHQHTELARKEWRPKEKLEELIDYEFLELCK
                     SDITTDDGCVDSSSSVSREAG"
     gene            17724..18536
                     /gene="spcF"
     CDS             17724..18536
                     /codon_start=1
                     /gene="spcF"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     amglyccycl: SpcFG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic"
                     /note="putative glycosyltransferase"
                     /product="SpcF"
                     /protein_id="AAD45551.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.3e-17,
                     bitscore: 52.3, seeds: 256, tool: rule-based-clusters)"
                     /sec_met_domain="SpcFG (E-value: 7.1e-118, bitscore: 382.5,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDEPSLPEESVTVVTLTRYRPVEVQRAMRSVRAQTTTTPVHHLVL
                     IDDNREIQSTLAEVAGDFPRCEIRYVPREPHETSGPGRSSRLRNLGVRHASSTWIAFLD
                     DDNEWDPDHLDSLLRCAREQGARAAFSDVSLLDKDGAPYREPRWPWARSTAEAEATYRD
                     LAARGVCEPGSNVIRHRMDVLDVPVDTSAWLLDRQLLLDVPFDDHFSAVDARDLVSEDD
                     KLFYQLVERGEPVAATGRPTLHYYLGGYSNSYETVAPTERDAISWASE"
     gene            18565..19383
                     /gene="spcG"
     CDS             18565..19383
                     /codon_start=1
                     /gene="spcG"
                     /note="putative methyltransferase"
                     /product="SpcG"
                     /protein_id="AAD45552.1"
                     /transl_table=11
                     /translation="MTELTPTEDRCPLEAEHGSYHWGNSLELMKGIPDASVDAVVCSPP
                     FEGDALISDEGRRGDAFVAWIEPFFRQFQRVLRPAGCVAFELGGIWLSDAPGKAVQHAS
                     ALRALVASGWRLVQDFYYYNPQLLQPQPGGPPRAADSVTPVWVMARTHDVHYDVEALRR
                     GDRRSVVRGNLLEFDSSGPWDQAYEKALARQRLEPYGDRWPTAVPELFIELLTRPRWTG
                     PRPGSPAPGATCFAAERLRRRWIGVERDRGLEQHVRAMFAAGRDEPSVLA"
     gene            complement(19458..20498)
                     /gene="spcH"
     CDS             complement(19458..20498)
                     /codon_start=1
                     /gene="spcH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 191.7; E-value: 3.5e-58)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative dehydrogenase"
                     /product="SpcH"
                     /protein_id="AAD45553.1"
                     /transl_table=11
                     /translation="MRGAIIGFGTIAMGHMGGYSRVEELEITAVLDISKERREYAENTY
                     GLTAYSDFAKLVANEDLDFIDICTPPGSHAEYSALGLANGLHVLCEKPVFLPEQDGGYQ
                     KQMDLIRESDRVYYPCHVYKFAPVLASLKERIQNPAFGEVLGANFRTLRTGHAKGVPEW
                     RMHWRREPETSRGGILRDHGPHSIYLAMNLTGCTPRSVSCLTGRMREGSAYRDTEDSAL
                     LRIRCDNDVEIAMTLSWAAGHRSTGYSVIGSGGSVVVDGDELTAGVGGEVVRTSIESGF
                     DDPSHKEWFPGMLRDFLRTAVEPGCQAELIREALTTSIVIDAAYASAADEGRWVDCTVP
                     EDLLPA"
     gene            20691..21629
                     /gene="spcI"
     CDS             20691..21629
                     /codon_start=1
                     /gene="spcI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     189.3; E-value: 1.8e-57)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative dNDP-glucose-4,6-dehydratase"
                     /product="SpcI"
                     /protein_id="AAD45554.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.2e-13, bitscore:
                     39.2, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVQMKAPGTGFSRKAGTAVVVGASGFIGSRLCRALESIGIRTIGF
                     SREKPFAPFGSVRKELLRADTIYYVAGSSTPALAEERPELVKADHWNLQMLLWSLIKVT
                     HRPLVVLASSGGTVYAPDAPQPFHETAPTRPSSAYGAAKLAQERALTAADWTVPVILRF
                     SNLYGAGQRPRRGYGVIAHWAKAVHEGRPVTLIGSSSRDYLHIDDAVEALLAVHRHVAS
                     LRAARTPITLNIGSGIPVSLDELHRSFEVAAGHSIPVERRPARSFDRTDVCLDVTAAAE
                     LLGWAPRVPLREGLAQTLAAFARRQWPIQSP"
     gene            complement(21694..22680)
                     /gene="spcJ"
     CDS             complement(21694..22680)
                     /NRPS_PKS="Domain: NAD_binding_4 (4-183). E-value: 7.9e-18.
                     Score: 56.3. Matches aSDomain:
                     nrpspksdomains_spcJ_NAD_binding_4.1"
                     /codon_start=1
                     /gene="spcJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     324.2; E-value: 1.5e-98)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative dehydratase"
                     /product="SpcJ"
                     /protein_id="AAD45555.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.1e-17, bitscore:
                     54.5, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 9.1e-22,
                     bitscore: 68.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 3.1e-18, bitscore:
                     56.3, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILVTGGAGFIGSEFVRSLLLTAEPERNTPWVTVLDKLTYAGVA
                     ANLDPVAGHPRYRFVRGDICDAHLADHVMRGHDAVVHFAAESHVDRSISGAGPFVTTNV
                     VGTQVMLDAAYRHGVGRFVQVSTDEVYGSISEGSWSEGAPLDPNSPYAASKAGADLLAH
                     SYHRTHGMDVVVTRCSNNYGPRQFPEKVIPLFITNLLDGREVPLYGDGQHMRDWLHVSD
                     HCRGIRLALRHGKAGETYHIGGGTELTNEALTGLLLEATGRGWDSVRRVPDRKGHDLRY
                     SLRCDNARQHLGYEAEVGFEKGLADTVAWYRNNRSWWEPLKRRMAQP"
     aSDomain        complement(22132..22668)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_spcJ_NAD_binding_4.1"
                     /evalue="7.90E-18"
                     /label="spcJ_NAD_binding_4.1"
                     /locus_tag="spcJ"
                     /protein_end="183"
                     /protein_start="4"
                     /score="56.3"
                     /tool="antismash"
                     /translation="VTGGAGFIGSEFVRSLLLTAEPERNTPWVTVLDKLTYAGVAANLD
                     PVAGHPRYRFVRGDICDAHLADHVMRGHDAVVHFAAESHVDRSISGAGPFVTTNVVGTQ
                     VMLDAAYRHGVGRFVQVSTDEVYGSISEGSWSEGAPLDPNSPYAASKAGADLLAHSYHR
                     THGMDVVVTRCSNNYG"
     gene            22859..23770
                     /gene="spcK"
     CDS             22859..23770
                     /codon_start=1
                     /gene="spcK"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     amglyccycl: SpcDK_glyc"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 247.8; E-value:
                     2.3e-75)"
                     /gene_kind="biosynthetic"
                     /note="putative thymidylyltransferase"
                     /product="SpcK"
                     /protein_id="AAD45556.1"
                     /sec_met_domain="SpcDK_glyc (E-value: 1.7e-206, bitscore:
                     674.1, seeds: 2, tool: rule-based-clusters)"
                     /sec_met_domain="NTP_transf_3 (E-value: 3.1e-13, bitscore:
                     40.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGILLAGGTGSRLWPVTRAVSKQLMQIFDKPMIYYPLSTLMMAG
                     IREILIITTREDQPGFRRLLGDGSHLGIEITYAVQECPEGIAQAFLIGSDFIGAETVAL
                     ALGDNIFHGQAFGRRLRAHRNLSGARVLAYPVADPSAYGVVEISETGAAVSVEEKPEKP
                     KSRYATVGLSFYDHRVVDIARGLRPSERGELEITAVNEEYLRRGELAVTVLDRGTAWLD
                     TGTFSAMVQASEYVRVMEERQGLKIGCVEEVAWRCAYIDDDQLRELGRPLLKSGYGDYL
                     LALLDEPRTHHGFPLPAAEDAW"
     CDS             complement(25122..27161)
                     /codon_start=1
                     /note="homolog to transposase"
                     /product="Orf4"
                     /protein_id="AAD45557.1"
                     /transl_table=11
                     /translation="MVALSGQDIHLVGPDGGGEAVLAGHLFTDPGFTVVGADALQAAPQ
                     WGLFETAPAAAREKALAWQRHVREVECGLPGGLGSEGVVGPQYDPEQHTLAEREQAKAQ
                     ELTALGFGRVSRTTVQRMRLAYRKQGLWGLLDHRTTRASSPTGRADERVVAAVREALRR
                     RLGRSKGTINGLFPLINQILEDRNGPGTVPAPSQATLYRLVTALARPGELPSGPVRQVP
                     ASVDGQAFTPATALRPGEQVQVDTTRPDVLALFDDGRLARPELTIAVDVATRAILAAVL
                     CPSATKAVDAALLLAEMAVPHPARPTWPDILRMDHAPALPHQRLAALDERLAGAAARPV
                     ALPETIVFDRGKVFVSAAFTAACEHLGISVQPAPPHAPTAKGIVERTFGTINALFCQHL
                     PGYTGYTGSDVTRRGPDTEKDACYSVAQLQDLLDEWLVHYHHRPHEGLRHPMMPRKALT
                     PNQMWAALVAVAGHVPVPLTGRDYLELLPVRWQAITPAGITIHHRTYDHDLLAPYRGQP
                     SPVAGRGGKWEIHYNPHDVRQIWIRLTDGDLTEIPWIHRDHVHQPFNDHTWQHIRTHAH
                     HNNHDDSQQHEAGLADALDQLMRRVHSGHATTTEQALLARATTLPVPAARPPQHGTGPA
                     TDESAQHGEDDSIDDLDDLPDDDTRPAAAAGFGLYDAYEEADRW"
ORIGIN
        1 ggatccgcag tctgagcaga ctttcgctcc ctgcgtcctg gctggctgtt tctctccgat
       61 gggttctacc tcccatgcca tgaggggcaa gggaggaatt tcgcgcgcct gacgggagcg
      121 ctctgaaagc gagtccttcg ttgcccctcg gtcggtcatg acgtaccgag ggaagatccc
      181 catgatcaaa tggaagttcg ggcaccgacg cgctggccgt gaacaggctg ctggcggcgg
      241 aacagctcct gccgcgccgc agcgctcggc ggaaagccgg gatgccgctg accacatcaa
      301 gcagtcggtt atgcgaggag ccgctgcagg agttgcgcgc tcgctgacgc agaaggtgtg
      361 ggagagcgtc ttcggcgcct agtactgcaa cggtctttgc tgtgacgggt gggtaggtcg
      421 gtcgttggtg tggttatggg tggggtcctt gcgagtgcca gattgtggga tggggaactg
      481 agcgtggtgc acgagcggtt cgtgcaccgg ttcaaccggg aggagccgcg gcagtcggcc
      541 cttgcctata tgcgagggtt gaccgctcct ctggagcgga agaacggctg gacgctcgcg
      601 gaagaagccg gccacgcggg tcctgaccgt atccaccggt tgctgaaccg gatcgagtgg
      661 gacgccgacg aggtcctggg cgacgtgcgc gactacgtcg tcgagcatct cggggaccgg
      721 aatgccattc tgatcatcga tgacacaggc ttcctcaaga agggcactcg ctcggcgggt
      781 gtgcaaaggc agtactccgg cactgccgga cgcaccgaga acagccagat cggggtgttc
      841 ctcgcctacg ccacgcgccg cggacgcacg ttgatcgacc gccgcttgta tctgcccatg
      901 tcatggaccg gtgaccggga caggtgccgg caagccggca ccgacgacag tgtcaccttc
      961 gagacgaagg ttgccatggc caaggcgatg gttcgccggg cgatcaggga ccggatcccg
     1021 ttcggctggg tgacggcgga cgccgcctac ggatacagca agggctggcg cttcgagctg
     1081 gaacaggccg acgtcttcca cgtcatggcc accacccggc acgacaccgt cgtcacccgc
     1141 tggtccatcg accatcctgt ccacgacctg ccacggcaga agtggaaacg ccgctcgtgc
     1201 ggcccggggg cccacggccc gcgcgtctat gactgggccc gtgtcgaggt ccggccctgg
     1261 catcgcgagg accgccggca ctgggtcatc gcccgccgca gcgtccgccg gcccgaggag
     1321 atctcctact acgtcgccta ctgccccacc gagaccactc tggacgagct gatctccgtc
     1381 gccggcagcc ggtgggccgt cgaggactgc ttccagagcg cgaagcagga atgcggcttg
     1441 gacgactacc aagtccgccg ctaccccggc tggcaccgcc acatgaccct ggccatggcc
     1501 gcccacgcct gcctcaccgt cctgcaggcc cgcgagctcg acacggagaa agcagaaacg
     1561 gatcctccca gctcatcccc ctcagccttc ccgagatcag acgcctgatc acccgcctca
     1621 cccaccgccg acctgcctca gtcgaccacg tcctgcactg gtcacactgg cgccgcagac
     1681 ggcagtacca agcccgcgtc tgccactaca aacgacgcgg acacacccca ccagaagttg
     1741 cccacccgtc acagcaaaga ccgttgcagt actaattacc ccccttgtcg tcggtaagct
     1801 cgctgcataa tctgaagtcg tcctgatcga accgagaaag gattcctcac gaattcccag
     1861 ttcgctgccc cctcgacgac tcagatcaac ccgatgcacg aggagcgcgc cgacgccgcg
     1921 gtcttcgaga tcgagatcga ggaagttgag atggtgccct cgctcctgaa gcagggttgc
     1981 atctgctgaa ctgcccccgg gtgcccgacg cggttcgctg cggccgggca cccgggggca
     2041 atccccgtac ggagtggaag tgctgcacat ggaatcgcat gacccggttt gcgtaggcga
     2101 ccgacaggca cgagagagtg atgctagtca gatcgcggag gtccaggcca gcgcatggcg
     2161 caacgcctac gcgagcatcc tgacggccgc ggaactcgag ggtctcgaca ccgccgcgct
     2221 cactgatttc tggcgcgcgc agattgcagc gacagcccag gcgtccgccc atgtgctggt
     2281 ccacgacgac ggggaacgga tcgcgggatt ctcggccttt ggaccggccc gtgacgacga
     2341 cctccggcag cggccggaca ccgaagagct ctacgccttc tacgcccggc cggaatgctg
     2401 gggccagggc gttggacaca gtctaatgct ctccacgctc tccgtatggg ccgataaggg
     2461 cacgcggacc gcgtacctgt gggtgctgga gcgcaacgaa cggggccgca ccttctacga
     2521 gaagggcggc tggcggccgg acgctacggc cgccccctcc gggtccgatc ccggtgcgat
     2581 ggagatccgt tacctcctgt ccgagccgtc ggcgcgccgc gcggccgtgg agacaggact
     2641 cgacgcccgg acgaaaggac gatgacgttg tgcgcgtccg ctgtgcgatg gaccttcagt
     2701 tacggcgcgt ggcccaacgg tcgtacgtgc acagcccgtg cgggctgcgc tcgaacagcg
     2761 tgcgcctcct gcatgacgag cacctgctca cttgcaacga ggcccccgag cacccgcccc
     2821 gctccggtcc tgccggcgtc tgctccgcga tggaccccct tccaccgcgt gcccaggtgt
     2881 ccgccgggca tgccgccatg tcggccgggc ccttgcagga gcggtcggtg acatgggccg
     2941 tgagcgccgc gggtgtcgcg tcggtcagct gtgccgtggt gacgtttccg gtggcgtacc
     3001 cctcccggcg ggccagttcg agcagggtgg gcagcggctc gttggtgtcc ggtgtccggg
     3061 agatgcgccc gttgaccgtc ttgcgcccgg tggcccacgc cgtggcgccg gctgcggagt
     3121 cggtgacgta gtcggggtgg ccccgctcgt ccaccgcgga ggtcagggac gatccggtca
     3181 tcggcagccg gtccatcgtg agccgaccct cggcggcgac ggcgtagttg cgcgcggcgg
     3241 tgatctccga gtcacccatg ccgtcgccta tgaggaggat tacgttccgc gccggggagg
     3301 gcctgaaatc tccggaaact ggtccggacg gaggcgctgc ggaggacacg gtcaccgatg
     3361 tcagcaggac accggtgacc gcgccccacc gccgcacccg tcgctttccc tgccgcaccg
     3421 catggaccgg ccctccgcct cgtcggtccg gaaaagctgc cgtcatcgct caactccctt
     3481 gtgcaagagg cctggtgaac ggcggctacg gtatgggccc gtacgggtgg acgcaccggc
     3541 gtgcccgaag gctgggcacc tgtctatgtc gggtaacttg cggcggggaa cccaacttcc
     3601 cttgaaggaa atgcgacatg gacacgtcaa aagcgatcga ggtcccggaa cacctggcgg
     3661 cgtcgtacag caggggattc ggcgaggaag ggagggcctg gatcgctgcg ctgccgactc
     3721 tcgccgcggc attcctggac aggtgggaac tgcggcgcga tggtgcggcc cgggcagggg
     3781 aagcctcgct ggtactgccg gtgttacgcc aggacggtac ccgcgcggtc ctcaagctcc
     3841 agatgccccg ggaagagacc actgcggccc tcatcggcct gtgcacatgg aacggtgccg
     3901 gcacggtacg gctgctcgac cacgatcccc acagcagcac catgctcctg gagcggctgg
     3961 acagcgcccg caccttggcc tcactcgagg acgacgacgt cgcgatggga atcctcgccg
     4021 aactgctggc gcggctcgtc agcgtccccg ccccccggga actgcgccgc ctcaaagaca
     4081 tcgccgccga catgctggag cgggtaccgc gcgcggtcac ggccctggcc gacccggccg
     4141 accggcagtt gttgcgtggc tgggcggcgg ccgtcgccga actgatcgag gaacccggcg
     4201 accagatgct gcactgggac ctgcactacg acaacgtgct ggccgcggag cgtgagccgt
     4261 ggctcgccat cgaccccgaa ccgctcgcag gggaccccgg tttcgacctg tggccggccc
     4321 tggacagccg gtgggacgac atcgtcgcca cgggcgacac ccggcgtgtg gtgcggcgcc
     4381 ggttcgacct gctcaccggg gtcctcggtc tggaccgcgg gcgtgcggcc ggctggacgc
     4441 tggggcggct gctgcagaac gagctgtggg acatcgaggg cggtggctcc gccctcgccc
     4501 cgtcctcggt cgcgatggcg gaggcgctcc agaaccgttg acgcgcgggc ccgagagagt
     4561 tgacgtcgaa cgaatcggcg gtgccgtccg gcaccgccga ttcggctttt cccggaagag
     4621 tttcgcgttc gactgagaag attctccagt cgaacaacgg ccgtactcgc cgtcggtgcc
     4681 ccgacttcgc tatgctcacc gcgaattgaa tggcagctca caaaaaccat cggatacggg
     4741 tggtcgcgaa gtcggcccat gagttcgccg accgcgacgg agcgattctt acgaccgggt
     4801 ttccttgacc gccgaaggcc attgttccca gcaaaccgga gcccatcggt cctttcccgg
     4861 cgggctcttg cgaatgagta cccgttgacg tcccgacgga caactccttt tgttctcggg
     4921 gccttgccgc atccattgcc gacagccaat gaggagtgtc atgagtctgg tcagcgtgca
     4981 caacgaatgg gatccgctgg aggagatcat cgtcggaacg gccgcgggtg cgagggttcc
     5041 ccgggccgac cgcagcgtgt tcgccgtgga gtacgcgggg gagtacgaca gccaggatca
     5101 ggtgccgtcc gggccttacc cggaccgggt cctcaaggag accgaggagg aactccacgt
     5161 cctgtgcgag gagctcacga agctcggcgt cacggtccgg cgtccgcagc agcgcgacaa
     5221 ctccgccctg acccgttctt ccaagggcaa cgaccacggg tgaccccgac gaggtgtgtc
     5281 ggctccctcg cggcggagca gtgtgacgac cttgcggaaa tggcgcgggc tcagcccggt
     5341 gaacggcgct atccatgacg gctccgacgc cgtgatcaca ccagccatgt caagatcgtc
     5401 tcatcgtggc ctggcgcatc tgaggggcgc gtgattacag ggtgatgcgg ccggtcagcc
     5461 accattcgag gtacttggcg agacttggtg cgacccaggt acggctgtcg tcctcgtggt
     5521 tccatacgaa gacatcgggc cggctgattc ccgggaggag cgcgaagagg tctccgtttc
     5581 ccgcatccgc gaagaagagc aggggatcga aaggcatgta gagcgtggcg agctcagcgt
     5641 cctggcgcat ggtgaggttc tcggagacga tccgttccac cgaccagatc agaccatctc
     5701 cgtactcgcc ctcgatgccg ttgctctcac ggagaagagc ggcgaggtcc tgaggtagcg
     5761 gatggcggag gagattggcg catctgaaca gcgatgcctc cgaggccgct ggctgaaagg
     5821 ctgccggtcc gggcagggcg gtgaccaggt cggtccacac gtttgggtca cgctccaaga
     5881 gtcgggcctg ccacccaatg ccggagtggt cccgtcggct cgggctggtg cctcctcttc
     5941 tggacaggag gcacacctga tcgtcgcacg aggacaacga tggcggtctg gccggccgtc
     6001 tgcagggacg ccaccaatgc gggacaaccc ttactgttga ctcctgtagt acttgctctg
     6061 agaatcttgc ataagcagcg ggcaaatgac cgggccctgc tctgtacgtc gtgcgcgact
     6121 cgaccaaaaa ccgtatgcac ccagcgtcgg cccacggaag gttccgccgc ttcgacgtaa
     6181 gtcactggtc taatgatcag tgttcaggcg gaggggttct gaactcgtgc ttggcattgc
     6241 acacaagagt gtggtggcac catctatacg catgaagagg tccgattcgg gtggtggtct
     6301 ctgagtgacg acggtgaaag gcgcatgcgt ttccgttccc atcagtaagt tacttctcgc
     6361 cgactcccca agatcgcgcg ccgtcgattc cagccatgtg gagctgctgg cccagctcga
     6421 agaggtcctc ccgcccatca ccgtgcaccg tgactcgatg cgtgtggtgg acggcgtaca
     6481 ccggctggag gccgccaaag cacggggtgc cacggagatc aacgtggtgt tcttcgaagg
     6541 aacgttggag gacgcgttcg cgcacgcggt ggagaagaac gtccggcacg ggcttcccct
     6601 caccctccag gagcggaccg acgcggcggc tcggatcatg gcctcgcacg cggactggtc
     6661 cgacaggagg gtggcagcca cggcggggct gtcacgtaag gcagtcgccg ccatccggcg
     6721 tatgagcgcg gacggccggg ccggggaggc ggtgagaacg ggccgggacg ggcgcgtgcg
     6781 cccagtgagc agcgccgcgg ggagggagca cgccgcccgg gtgctccgcg agaacccggg
     6841 cgcgtccctg cgggaggtcg ccagggtcgc gggcatctct ccgagcacgg tgcgggatgt
     6901 ccggaacaga accgcgagcg gcgaggaccc ggtccccgtg cgccagcgcc cgccggaccg
     6961 gcggcccccc gtgcccgggc ccgccacacc gggcaccgtc cgcctcgcgg cggcacgtga
     7021 gcagcggatg gccgactgct cgcgtcgcta cgcgaacctc cttcacggcc tcaagagcga
     7081 cccctccgta cgtctcacgg agtccggtcg gctcgtcctg cggctcctgg agacccggct
     7141 catcctgatc ggtgagcggg accggctgct ccaggcgatc ccgcagcact gcgtacccaa
     7201 tctgtccgcg gcggtgcgcc agtgcgcgga ggcatgggac gagttcgcgc agcacctgga
     7261 gacgttcgag gcagctgagg aactcggcgc ggggtaacac ccgcgcacgt gtctgtggat
     7321 ggcggaacgc ttcgaccttt cagtggtccg gcagggctgg tgtgcaagtg gctccaggag
     7381 ccacttgcac accagcggcc aactggacag cacagcgcct gtccctacga gagagggcgt
     7441 cggcctctga tgagagaccg acgccccacg tgccaccgcc cttggtcagg cacctcgcgc
     7501 ggagcccgcc acgaaggcgc tgtattcagc tcggtacttc ggagttcaga tggtcgagag
     7561 tctcggcgaa gctctgccaa gcggcttcgg tgtcggaggt gcgctggtgt tccccgcgga
     7621 accactcgac gaactcggcg acgtccagca ggctccaccg cagccggtag agcgccagcg
     7681 cggccgggtc gggcgtgtgc ccggtcagtt cggtgtagcg ggcgagagct gccgggtcgt
     7741 ccgagatcag ggagaggtcc cgttcgggta tcgcgaggcc caccgtgtcc cagtccacca
     7801 gcacatagcc gtcctcacca aggatcaggt tccccgggtg cggctcgccg tgtgtgacga
     7861 ccagcggggc gccgcggccc cgtacccgcg ccaccagttc gccgaactcc gccatccgcc
     7921 cgcggagcgt cgcctcgtgc tcggccagca actcgcgggc cggctcggag aacggcccgc
     7981 ccgtccaggt tccggacggc tcggccagcg cggtgtgcac gccatccagt ccggtcggca
     8041 ccatgtcggt ggtcggggtg cacttcggcg gtgcctggcc gtgcaattct gcgagcagca
     8101 ccagcacctg gtcccgctcc cgctccgtca gcttctggcc gaactccccg ggtcgggccg
     8161 agacatgggg aaatacggtc aacgcgtacc gcgagtccag cgggaccagt gaagcgccgt
     8221 cactcgtggt ccggggtgcc accacgaacg gcaggccgcc ctgctcacgc aagtgcaccg
     8281 cggtgtccat ggctctccgc agacctcgca gtgccgccgg ggcaccgtgc ccgcagtgct
     8341 ccttgtgttc gaggtcggag acggtggcga accaccgctg cccgtcgtca ccggtgatgt
     8401 gccagtgata gtcgccgaag ccgagcggcg cgtacgacgc actggtcgtg gagataccga
     8461 attctcgtag tccctgaaat aggctttcct ggtccaggtt ctcaggaaga tcttccatgg
     8521 gggaacgcta acagcgtttc agggtcccta cggagggatt ctcgtcaaag tcgcgcatgc
     8581 gccgcagcgg cgagcacagc aggagcggag ccaccaccat cagggctccc gccaggatcc
     8641 acagagtgtc acgcactccc acggaggcgg cgagggctcc accggcggtc gcaccgagcg
     8701 gggcggcacc ccatacggcc cagcggaaca tcgccgccat gcggctgagg agttccggcg
     8761 ggcacacttg ctgacggtag gtcacctgca tgatgttgaa gacggtgatt ccgatactga
     8821 tcgcgatgtg tccgagagcg aacagcgcga cacgccagcc gtcgcccgtg agcggaatca
     8881 ggaacatgaa gggagcggcg accgggaccg cgagcaccgc ggtgcgacca ctgcccagcg
     8941 ccctggtcaa ccggggggcc agccacgcgc cgatcagcgc gcccacggcg cccgcggcca
     9001 gcaggaagcc gacgagcccc gcggtcaccc cgacgacttg gttcaggaag acgacgtcca
     9061 gtgccagcgc cgccgagaga atcaggttgt tcaggctcgc ggagagcgcg aggagccgca
     9121 ggaccgggtg tcgcagcagg acgctgatgc cgtgccaggt ctgtcggacc aggccgtggg
     9181 agggggcggc cggttgggcg tcgggcactg gaatgcgcca cagcagaagt gccgagagcg
     9241 ccgaggccag accgttgacc gccaccgcga ggtgggtgcc gagccactgc acggccacgc
     9301 cgccgatccc ggggccgccc agctccgctg tggcgcggat catctggagg ttgctgttcc
     9361 cctggaagag gcggtctttg acaaggaggt gcggcaggta gctctggtcc gcgatgtcac
     9421 cgaacaactg ggcgccgccg agcagcaggg ccacggcata gagatggggg agggacagtg
     9481 cgttgagcgc ccaggcgacc ggcagcgaca tcagcgccac gaaccgcagg agatccgctc
     9541 cgatcatgac gcggcgtggc cgcagccgct cgaccactgc ccctgcgggc aggccgaaca
     9601 cgaggtaggg agcgaagtgg aacgtctgga tgagcgccgt ttgccaggcc tgcgcgtcca
     9661 gggaaagcac ggcggtgagg gggagcacca ccagggtggc ggcggctccg gtctcgttga
     9721 gtgcgtgcga gccgaggaac aggcggtagc cgtgacggta tccgcggtcc aggtcgcggg
     9781 cgtcaggggc gttcgcgttc aggtcggcgg tggaggggcg ttctggcatt gctcacctcg
     9841 gcatcatcgt ggggcgcagc aggggaacgg gagttgaggc agccgtggaa accgcgcggc
     9901 tacgcgtgtc cgaggagcgt gcgcagcccc tgctccacac ccggcgtgca ggcgatgacc
     9961 atgcggtcgc tcgccgggcc gccgtcgaga tctccgaccc aggcacccgc ttcgctcgcg
    10021 atcaaggctc cggcggcccg gtcccagtgc cgggtgtcac tctcgtagta ggcgccgagg
    10081 cggccgcctg ccacccagca caggtccagg gccgctgacc cgctgctgcg gacgtcccgc
    10141 acccggcacg cgatgcgcgc ggccagcgcg gcctgtcgcg cgcgcaccgc gaggtcgctg
    10201 ctgaaaccgg tggacagcag gacctcggcc aggccgtcgg cggcgtgcgg cacgtgcagg
    10261 gcccggccgt tgaggcgggc gccccggccg cgctcggcgc tgaaggtctc ctgacgggag
    10321 gggtcgtgca ccacgcccac gacgccgaca ccgtccagtt cggccgccac ggagacgacg
    10381 aacgccgggt agcgggcgac gtagttggcg gtaccgtcca gtgggtcgat cacccagcgc
    10441 acacctgagg tgcccggcct ctctccgccc tcctcgccga ggaccccgtc atccgggcgg
    10501 tgcgccgtga gcagaccgac gatgtggtcc tcgctcctgc ggtcgaacac ggtcaccagg
    10561 tcggtgcggg aggacttcgc tgacgcgcgt acgggtccct cctccgcccc gcgcagcagt
    10621 atctgtcctg cctcccgcgc cgctgtgacg gcgagttctg tcaattcacc gctgtcaaag
    10681 gcgctgtgcg acgagaccat tgccccccct tgtagcgtcc ggaattccgt gtgaaggtat
    10741 caccacctcg caccttgggt gcatgccgtc cgcgctcctg caaaccgacc ggcattctcg
    10801 cggaatgcgg gcgcatggct atggtccccc ctcccataac tctcgacgtt ttggttggtg
    10861 ccgtgtcaga gacacaacgc atacgcatag gcgtgatcgg ttgtggcact gttgcccaga
    10921 tcatgcacct gccctatctc cggagcctac ccgcgcagtt cgagatattc gcgctcagtg
    10981 acctctcgcc cggtctgctc gacctcctcg gcgagcggta cggggtgccc gcgacccgca
    11041 gattcctgga ctaccggggg ctgctggaga gcgaggtgga cgctgttctg gtgctcagcg
    11101 ccggcagcca cgccccgcag gtactggccg ccgcagaggc gggcaagcac atcctggtgg
    11161 agaagcccct gtgtttcacg ctccgcgagg ccgacgagat cgcagccgcc gtgagcagat
    11221 ctcaagtgcg gctgatggtc gcgtacatga aacgcttcga ccccggtttc cggcatggcg
    11281 agcgcctcgt tcacgcgatg cgggagcctc ggtacgtgca gatcaacaca ttgcacccga
    11341 gcgaggacca gtacatcgac atccatgggg tgcaccgttt cggtgacatt ccccgggatg
    11401 tggcgcagcg ggcggaaaaa gcgcaggagg agctgctcga cgaggcagta ggggcagtat
    11461 ccagcgcgct tcggttcgtc tatcacgacg tgtttctcgg cagtatggtg cacgatatca
    11521 acgcgctgcg ttccctcgtg ggggaaccgg cgggcgtact cttcaccgat atctggcccc
    11581 cggattcgaa gttcccctcc gtcaccaccg ttctgcggca tgccggaaac cttcgtacca
    11641 cctacacctg gacgtacctt gccgaggtgc gggactactt cgaggagctc gcggtgttct
    11701 cctcgtccga gcgggtgcgc gtgcagttcc cctcgccgtt cctcaagcac tggccgacgc
    11761 ctgtcgtcgc acagcgcatg gagcacggcg cactcgtgga ggagcgggtc gaggtgtccc
    11821 acgccgaggc gttccgcgag gaactgctgg ccttccacga atgcgtcgtc agcgggtccc
    11881 agccgctcac ggacacagcg gacgcccgca cggacatcgc tgttctccag cagatcttcg
    11941 cggccttcga ccccgcgggg ctcggcggag aggcaaagac aagccggggt tgagaccgcg
    12001 cccgcagaag gggtacatcg tgagccacag cgtcaccctc ccgtccacca aggacatcat
    12061 cgagctggag agacggcacc ggctgcccgg cggccagtcc atgacggacc tcgcgggcat
    12121 cgtcgtcgac cgcgccgtca acgccgaggt gtgggacagg gacggcaagc gctacatcga
    12181 cttcttcacc ggggtgggtg tcagcaacat cggccactcc catcccgcgt tcctggaaga
    12241 gctgaccacg cagttgagca gatgcgcggt ggggacattt tacactgacg tacggtcccg
    12301 gtacttcgcc ctcctcgccg cccaactccc cgaacagctc ggggagatcc acatgttctc
    12361 gaccggcagc gaggcggtcg aggccgccgt caagctggcc agggccgcca ccggcaagca
    12421 cgagatcgtc agcttctggg gcgggttcca cggcaagact cagggtgcgc tgagcctgca
    12481 cgggggcccg cgcaagcacc ggtccgggcc gttcccgccc ggatcgcacc aggttcccta
    12541 cgccgactgc catcactgtc cgctccagct ggagcacccc gaatgcggcc agcggtgcgt
    12601 cgacctcgcg gagcagtcca tcgagaacgg ctccgtcggc gatctggcgg cggtcatcgt
    12661 ggagcccgtc caggggacga acgggaacat catcccaccc gagggctact tgcgcacgtt
    12721 gcgccaactg gccgaccggc acggcgcgtt gttgatcctg gacgaggtca tcacgggttt
    12781 cgggcggacc ggagcgctgt tcgccttcga gcacgacccc ggcatcgcgc ccgatgtcgt
    12841 cgtgctgggc aaggcgatgg cctccggggt gccggcgagc gccatcgtca gcaggtcggg
    12901 gctggtcgag ggcacgtcct tcgccgtgcc gagtgccgcc gcctcgacgt tcggcggcaa
    12961 tccgctggcc agcgccgcct cgctggccac cctcagggtc ctgcttgacg aacggctgcc
    13021 cgagcgctcg cacgaactcg ggaagtccgt gtcggatcgg ctgtccgcct ggcgggaaga
    13081 gttccccttc gtcggcaacg cggacaacat cggcctgatg atcggcgtgg agctggtgga
    13141 ccccgccacc cgccttccgc tgcccaaggg catcacccgg cgactcttcc aagaactcat
    13201 ggcccggggc gtcctcgcga tggcgtacga cagccggatc cggctctatc cgccgctgag
    13261 catcccgacg caccacctgg aggagggctt ggccgccttc gagggcgcct tccgggcgat
    13321 ggcccccgcc atcagccgac tgtgaccacg acgaccagag ggagagcgcc catggaactg
    13381 ggatgtgtcg tacggagcgc cgaggaggcc gagcacgccg ccggtctgcc gttcgactac
    13441 ggggagctga aaggagacat gctgtgcgtc ccgccggacg acctggcggc cctcaccgcc
    13501 cgcctgcaca gcgtccggct gccgttcaag gccatgacct caccgctgcc ccggcggtac
    13561 gggtgccggg tcgtgggacc ggaagcggac cacaccgggg cgctcaaggt cttccgcgac
    13621 atgtgcgacc ggggcgccgc gctcggcgtg tgcaccgtcg tgctcggcag tggacaggcc
    13681 aggcacgtgc cgcctggctt cccggcccag gacgccgacc gacagctccg ggacttcctc
    13741 ctcgcggcgt ccgacgtatg cgccgagcgc gacatgaccc tggctctgga gcacctgaac
    13801 cggacggaga cgaacctcgt caactcctgc actgaggcac gcgccgtcat cgacgcactc
    13861 gaagcccccg gtgtccggat caccgctgac tgcttccatc tcatcagcga agggctcgac
    13921 atccgtacgg aggtcgccgt cgcgggcggc tccatcgcgc acgcgcacac ctccgccgtg
    13981 ccgcgcggca gcggtgactt ccgcgaagag gcccagcgtg agttcgtctc ggcgctgcgg
    14041 gccgccgggt atgacggcgg cctgaccgtc gaggacgagt tccgcgactt cggccgggag
    14101 gcgggagagg ccgcgatcct cttccaccgc gtcatcgagg aggcgaacgt cctgctctga
    14161 acgaccgtgc tgccccgccc ggccgcgcca tccggcccgg ccgggccatc ccgaagccga
    14221 aggaccttca ccgcaccgac cccgggaggg aaaccgcgtg gcactgacct tcctcaccga
    14281 ccacaccgcg cccctcatgc gggggctcgc tgaccgcgtc gtcgccgact ggcacgagcg
    14341 acatcccgag acacccgtcg agctcgccgt gctcgaccac gaggaactcc gcgacgaatt
    14401 gcccgcgcgc ctgaccggag ccccgtcggc cgacatcatg acctggttcg cgggcaatcg
    14461 gatggacgcc ctggcgggca aggacctgat gctgaacatc tccgccatgt ggaaggccga
    14521 ggggttcgac gccgtctacc tcccccggtt ccgcaacatg accggcggca tgggcccctc
    14581 gtacttcctg ccgacctcgc actactggtg ggcggtctac taccgtccct cggtcttcgc
    14641 cgcggcgggc atcaccggca ctcccaccac ctgggacgaa ctcactgccg cctgccgggc
    14701 actgaagtcg tccgggatca cccccttcgc actcggtgcc cgctaccgct gcccggccgc
    14761 tgcctggttc gactacctca acatgcggct caacggcccc gacgtgcacg acgccctgat
    14821 gaggctgcgc atcccgtaca cggacgaccg gatccgccgg gtgttcgcct tctggcggga
    14881 actgatcgag caggagttct ttctcggcga cccgggcgac tacgacgagg aggaggccgt
    14941 cgccgccgtg ctgcgcggcg aggcgggcat gacgctcacc ggcgcctacg ccaccgacga
    15001 atacaccccg cagggggaac cggacatcga cttcttccgc ttcccggtca tcgacccgac
    15061 cctgcccatc ggtgaggaca cccccgtcga cggctacttc gtgcccgcca acaccgactc
    15121 gcccgaggaa gccacgcgct ttctcgcgta cctcggctca cgccacgtcc aacaggtcac
    15181 catcgagcgg ctctccaccc tgccgacccg taccgacgtg gacaccgaga agggagggcg
    15241 gcatgtggcc aagggcatgc gcatcctcca gggagccgac cacctgagcc agttctacga
    15301 cctcgacacc ccctgggaac tggcgaacgt cggcatgtcg gcgttcgtgt ccttcaccca
    15361 ggaccctgcc cgcggcgagg aactgctgcg cgaactggaa tccgcacgcc agggccagct
    15421 gcgccgacgc gggccggcga caccgcgctg aggggcgtga ccggagctca tccgccgcac
    15481 ccgcacttca ccgactcagg gagaaagatg acccccatac gcagttcccc gttggcgctc
    15541 cacggcgggg caccggtcca ccacggcgct tggcccgtct ggccgcaggc gccggagtcc
    15601 actctcaccc tgctcaagga ggcggcgacc tccgggcgtt gggcgatcag cggcgcctac
    15661 accggtacgc cgagcttcga gcgccgcttc gccgacgctt tcgccgccta tcaccaggtg
    15721 ccctacgcgg tgcccaccac caacggctcg gccgcgctca ccatcgccat ggaggcgctg
    15781 ggtgccgggc ccggtaccga ggtgatcgtc ccggggctca cctgggtggc ttgcgcgtcg
    15841 tccgccgcgg cactgggcgc cacaccggtt ctggtggacg tggatcccga gacgctcagc
    15901 atcagcgccg acgcggcgaa ggccgcggtg accgaccgca ccgtggcgat actggtcgta
    15961 cacgcctact gctccagcgc cgacatcgac gcgtttctcg aactgtccag gagcaccggc
    16021 atccccctca tcgaggactg ctcccaggca cacggcgccg agtggaacgg ccgcaaggtc
    16081 ggcacctacg gcacgatcgg cgtgttcagc ctccagcaga ccaaggtgct caccagcggc
    16141 gagggcggca tcgccatcac ctcggacgac gacctctacg accggctcca gcaataccgg
    16201 gccaacggcc gccgctgggg ggcacggccc gttctccacc aactcgagct ggaggacgtc
    16261 ggtacgtacg agggccacaa ccacgcgatg tccgagttcc acgcggctgt cgccctcagc
    16321 caactcgacc acctggacgc gcagagcgcg ctgcggagca cgaacgcgga ggtcctgaac
    16381 ggcctgctgg agcggatacc cggcgtgtcc acggtaccgg cccccgccgg tctgacacgg
    16441 cgcacctatt acgactacgt catccggctg gacccggacc tcctcggcgc ggtgcccatc
    16501 gatcgcgtgg tcgacgcgat ggcagccgaa ctgggcatgt tcttcgagac cctggacgcg
    16561 cccctcaacg ccaacaagct ctacgggccg ctcaagtcac cccgtacgcc cccctcggag
    16621 gccgtacggg agaagctgga cccggcgcgg ttcccactgc ctgccgcgac cgccgccttc
    16681 cacacgtgct tcgccttcct ccaccaggcg ctgctcgcca ccccggagga acgtggcggc
    16741 gatcgccacc gccgtcgaga aggtggtgcg gaacatcgat cggctccgtg aaggcccgga
    16801 aggagccgca cgatgagcgt gcacgtggag cacgggaaag tgatcaaccc cgaaggcgtt
    16861 gaaatcaacg ccagtctcca gtgcaacatg cgctgtaagt cctgcgcgca cctctcgccg
    16921 ctcttccgca aggagaacgc cgaccccgcg gagacgcacg acatcctcac cctcctcgcc
    16981 aggaactacc acgcctccta cgccaagatc atgggcggtg agccgctcct tcacccggac
    17041 atcgtcgggc tgatcgaggc ggtgcggacg agcagggtcg ccgacaccgt cctggtggcc
    17101 accaacggca ctctccttga ccgggcgtcg gaggagttct ggcgggccgt ggactccctg
    17161 gagatctccg tctaccccag ccgcccactc acctccgagc agatcgaccg ctaccacggc
    17221 atggcacggg aatacgacgt gtccctgctc atcaaccact acgggcactt ccgtgagatc
    17281 tactcggaga ccggcgcgga ctcacctgag ctggtgcagg acgtgtacga cacctgcaag
    17341 ctcgcccact actggcgttc acacacggtg tacgacggct ggctctaccg ctgcccacag
    17401 agcctgttcg tcccccagca gttggagaat ggcggctggg acccgcgcga ggacggcatc
    17461 gagatcgcgg acgatcccgg tttccttgag cggctgcacc gcttcctcac caggaccaca
    17521 ccgctgcgcg cctgcgggaa ctgcctgggc agcgtgggcc gactgcacca gcacaccgaa
    17581 ctggcccgca aggagtggcg gccgaaggag aagctggagg agctgatcga ctacgagttc
    17641 ctggagctgt gcaagagcga catcaccacg gacgacggct gcgtcgactc gtcgtcctcc
    17701 gtctcgcggg aggccggctg accatggacg aaccgtcgct gcccgaagaa agcgtcaccg
    17761 tcgtcacgct gacgcgatac cgaccggtag aggtccagcg ggcgatgcgc agcgtgcgcg
    17821 cccagacgac cacgacgccc gtacaccacc tggtactcat cgacgacaac cgggagatcc
    17881 agagcacgct ggccgaggtc gccggggact tcccccggtg tgagatccgg tacgtaccgc
    17941 gcgaaccgca cgagacctcg ggccccggcc gctcctcccg cttgcggaac ctcggcgtga
    18001 ggcacgcctc cagcacctgg atcgccttcc tggacgacga caacgagtgg gaccccgacc
    18061 acttggacag cctgctgagg tgcgcgcggg agcagggagc ccgcgccgcc ttcagcgacg
    18121 tgagcctcct ggacaaggat ggtgcgccct accgggagcc ccgctggccc tgggcgagga
    18181 gcaccgccga ggccgaggcc acgtaccgcg acctcgccgc gaggggcgtg tgtgagccgg
    18241 gttccaacgt catccggcac cggatggacg tgctcgacgt acccgtggac accagcgcct
    18301 ggttgctcga tcgtcaactg ctcctggacg taccgttcga cgaccacttc tcggccgtcg
    18361 acgcccggga cctggtgagc gaggacgaca agctcttcta ccagttggtc gagcggggcg
    18421 agccggtagc cgccaccggc cgcccgaccc tccactacta cctgggcggc tactccaaca
    18481 gctacgagac cgtcgcgccc acggagcgag acgccatctc ctgggcttcc gaatgaccgc
    18541 cgtaccggaa gggaccacac cgtcgtgacc gagctgaccc cgaccgaaga ccgctgcccg
    18601 ctcgaagccg aacacggctc ctaccactgg ggaaacagcc tggagctgat gaagggcatt
    18661 ccggacgcca gtgtggacgc tgtcgtctgc tcccccccgt tcgagggcga tgccctgatc
    18721 tccgacgagg gccgcagggg tgatgcgttc gtcgcatgga tcgagccctt cttccggcaa
    18781 ttccagcgtg tactgcgacc ggcgggctgc gtcgcgttcg agctgggcgg catctggctc
    18841 tccgacgcgc cgggcaaggc ggttcagcac gcgtccgcgc tccgggccct tgtcgcctcg
    18901 ggctggagac ttgtgcagga cttctactac tacaacccgc agttgctcca gccgcagccc
    18961 ggcggcccgc cccgagcggc cgactcggtc acgcccgtct gggtcatggc caggacgcac
    19021 gacgtgcact acgacgtcga agcactgcgc cgcggtgacc ggcggagcgt ggtacgcggc
    19081 aacctcctgg agttcgactc atcgggcccc tgggaccagg cgtacgagaa ggcgctcgcg
    19141 cggcagcgac tggagcccta cggggaccgc tggccgacgg ccgtccccga actgttcatc
    19201 gagctgctga cccggccccg gtggactggt cctcgacccg gttcgccggc accgggcgcc
    19261 acctgcttcg cggccgagcg gctgcgcagg cggtggatcg gcgtcgaacg cgaccggggc
    19321 ctggagcagc acgtgcgcgc catgttcgcc gccggtcggg acgagccgtc ggtcctggcc
    19381 tgacgacatg ccgtcggtcc tggcctgacc ctcctgcggc cgtggcggca ccgcgtccgc
    19441 cacggccgca gggctcttca cgccgggagc aggtcctcgg gcaccgtgca gtcgacccag
    19501 cggccctcat cggccgccga ggcgtaggcc gcgtcgatca cgatcgaggt ggtgagggcc
    19561 tccctgatca gctccgcctg gcacccgggc tcgacagccg tacggaggaa gtcccgcagc
    19621 atgccgggga accactcctt gtgcgacggg tcgtcgaacc cggactcgat ggaggtccgc
    19681 accacctcgc cgcccacgcc ggcggtgagt tcgtcaccgt cgaccaccac ggagccgccg
    19741 ctgccgatca cggagtaacc ggtgctgcgg tgcccggcgg cccatgacag cgtcatcgcg
    19801 atctccacgt cgttgtcgca gcggatccgc agcagggccg agtcctcggt gtcccggtag
    19861 gcgctcccct cccgcatccg gccggtgagg caggaaaccg accggggcgt acagcccgtc
    19921 aggttcatgg cgaggtagat gctgtgcggg ccgtggtcgc gcaggattcc gccccgcgac
    19981 gtctccggct cgcgtcgcca gtgcatcctc cactccggga cgcccttggc gtgtccggtg
    20041 cgcagcgtgc ggaagttggc gccgagtacc tccccgaacg cggggttctg gatgcgctcc
    20101 ttcagcgagg cgagtacggg cgcgaacttg tagacgtgac acgggtaata cacccggtcg
    20161 ctctcccgta tgaggtccat ttgtttctgg tagccgccgt cctgctccgg caggaagacc
    20221 ggtttctcac acaggacgtg caggccgttc gcgaggccga gcgccgaata ctcggcgtgg
    20281 ctgccgggag gggtgcagat gtcgatgaag tccaggtcct cgttggcgac gagtttggcg
    20341 aagtcgctgt aggcggtcag accgtacgtg ttctctgcgt actctcgacg ctctttcgag
    20401 atgtcgagca cagccgtgat ttctaattcc tctacccgcg agtacccgcc catgtgtccc
    20461 atggctatgg taccgaagcc aatgattgcg cccctcactt ccgcctcctt caggagtagt
    20521 gacgtgcatt attggtactg ggacgtcagg tcaggtgtca atcgtgcagc gaagcgccga
    20581 tatagctgac ccgttccgga aacagggaaa caggcggaag acgggtgata aaaagtcctg
    20641 ttggacgtac cctcttcgga accgttcggc gaggaaaggg gagaacgcgc atggtgcaga
    20701 tgaaagcgcc cggcacaggc ttctcacgga aggccgggac ggccgttgtc gtgggcgctt
    20761 cgggcttcat tggaagtcgt ctctgccggg ccctcgaatc catcggcata cgcaccatcg
    20821 gtttctccag ggaaaaaccg ttcgccccct tcgggagtgt ccgcaaggag ctgctcagag
    20881 ccgacacgat ctattacgtg gcaggcagca gcaccccggc gctggcggaa gagcggccgg
    20941 aactggtcaa ggcggaccac tggaatcttc agatgctcct gtggagtctc atcaaggtca
    21001 cgcaccggcc cctggtcgta ctcgccagct cgggcgggac cgtctacgcg cccgacgctc
    21061 cgcagccgtt ccacgaaacc gcgcccaccc ggccgagctc ggcgtacgga gccgcgaagc
    21121 tcgcccagga gcgcgcgctg acggcagcgg actggaccgt cccggtgatc ctccggttct
    21181 ccaacctcta cggcgccggc cagcggccgc gccggggcta cggggtcatc gcgcactggg
    21241 ccaaggcggt gcacgagggc aggccggtca ccctcatcgg cagctccagc cgggactatc
    21301 tgcatatcga cgacgctgtc gaggcgctgc tcgccgtcca tcggcacgtc gcctcactgc
    21361 gagccgcgcg gacgcccatc acgctgaata tcggctcggg cataccggtc tcgctggacg
    21421 agctgcacag gtccttcgaa gtcgccgcgg ggcacagcat ccccgtggag cgcagacccg
    21481 ccaggagctt cgaccgtacg gacgtctgcc tggacgtgac ggcggccgcc gagctcctcg
    21541 gctgggcccc gcgggtccct ttgcgggagg gcctcgcgca gaccctggca gccttcgcgc
    21601 gtcggcagtg gcccatccaa agcccgtgac gcgggtgctc cgtgggcggt cggccatggc
    21661 cacgggccgg cccgccctct gcgccgtccc gccctatggc tgcgccatcc tgcgcttcag
    21721 cggctcccac caggaacgat tgttccggta ccaggcgacg gtgtccgcca ggcccttctc
    21781 gaacccgacc tcggcctcgt accccagatg ctgccgcgcg ttgtcgcagc ggagcgagta
    21841 ccgcaggtcg tgccccttgc ggtcgggaac ccgccgcacg ctgtcccagc cacggcctgt
    21901 cgcctccagc agcagaccag taagcgcctc attggtcagc tcggtgccgc cgccgatgtg
    21961 atacgtctcg ccggccttcc cgtgccggag tgccaaccgg atcccgcggc agtggtcgga
    22021 cacgtgcagc cagtcgcgca tgtgctgccc gtccccgtac agcggcacct cccggccgtc
    22081 cagcagattg gtgatgaaga gcgggatgac tttctcgggg aactggcgtg gcccgtagtt
    22141 gttggagcac cgggtcacca ccacatccat gccgtgcgta cggtgatatg aatgcgcgag
    22201 cagatccgct cccgccttgc tggccgcata tggcgaatta gggtcaagag gggcgccctc
    22261 gctccaggag ccctcggata tcgatccata gacctcgtcc gtcgacacct gcacgaatcg
    22321 accgacaccg tgccggtacg ccgcgtccaa catcacctgc gttcccacga cattggtcgt
    22381 gacgaaaggg ccggcccctg agatggaccg gtccacgtgc gactcggccg cgaagtgcac
    22441 cacggcgtcg tgtccccgca tcacgtggtc cgcaagatgc gcgtcgcata tgtcaccccg
    22501 cacgaaccga tatctgggat gcccggcgac cggatcgagg ttcgctgcga cacccgcata
    22561 ggtcagcttg tccagcacgg tcacccaggg cgtgttcctt tcgggctccg ctgtcaagag
    22621 cagcgaccgg acaaattctg aaccgatgaa tccagcgccg ccggtgacga gaatccgcat
    22681 gcctttcaga gtacgcgcgc tccgccgcag tgcaaatggt gtgcaaaatt cggcagatgc
    22741 cgacacttgg ctgtctcgat aaaatgccca atcattgcga gggacgaagt cgtcgcagtc
    22801 cgacgtgtga aaggagggtg cgggccggtc ggcggggcgg accggcccgc cgtcgttgat
    22861 gcgtggaatc ctcttggcag gtggcaccgg gtcccggctg tggccggtga cccgagcggt
    22921 ctcgaaacag ctcatgcaga tcttcgacaa gcccatgatc tattatccgc tgtccacgct
    22981 catgatggcg ggaatccgcg agatactgat catcaccacc cgggaggacc agccgggctt
    23041 ccggcggctg ctcggcgacg gctcgcacct gggaatcgag atcacgtatg ccgtccagga
    23101 gtgcccggag ggcatcgccc aggcgttcct gatcggctcc gatttcatcg gcgccgagac
    23161 cgtggccctc gctctcgggg acaacatctt ccacggccag gcgttcggcc gacggttacg
    23221 cgcgcaccgg aatctgtccg gagcccgcgt actcgcctac ccggtggccg acccgagcgc
    23281 gtacggtgtc gtcgaaatca gcgagaccgg tgccgcagtc tccgtcgagg agaaaccgga
    23341 gaagcccaag tcccgctacg cgaccgtcgg tctgtccttc tacgaccacc gcgtcgtgga
    23401 catcgcccgc ggcctgcgcc ccagcgagcg gggcgagttg gagatcaccg cggtcaacga
    23461 ggagtacctg cgcagaggtg aactggcggt cactgttctt gaccggggca cggcctggct
    23521 ggacaccggg acgttctccg ccatggtgca ggcatcggag tacgtccgag tgatggagga
    23581 acgccagggc ctgaagatcg gctgcgtgga ggaggtcgcc tggcggtgcg cgtacatcga
    23641 cgacgaccag ctgcgcgaac tcggccgccc cttgctcaag agcggctatg gcgactacct
    23701 cctcgccctc ctcgacgagc cccgcaccca ccacggtttc cccctgccgg cggccgagga
    23761 cgcgtggtga acccgtccgg cgctcgcgcg gcatgagccg ttggggcctg cccttgcgtg
    23821 acaaatggat gaagacggcg ttgccgctaa cgcttggagg ggggtttgtt ggtgtatcgc
    23881 gggcttgctg gcctggtgtg ttgtgggttc gttgagagtg gccgggtgcg cggttccagc
    23941 gggtagttcg gggtgtgagc tggggctgtg tcgtgtgtgc tgagtgggat cgggttcgtt
    24001 gtgggtttcg ctagcgcgta aaggctcggt tggtgtttgt gctggtcagc gctgttttgt
    24061 ttgttcggtg ggcgggggtt agcggttgcg ggtggggcgt ctgtgttgtt cggcgaggtg
    24121 gtcgagcttt acggcttcga ggctggtttt ggtgatgcgt tcggtgccgt cgtggatggc
    24181 ggtgatggct gcttggcgga taagccttgt gagagatccc gatgcggccg gcggtgcgct
    24241 ggtggaggta ggcggcgtgc cggaggagga cgccgggttt gtggtgggtg aggtcgaggg
    24301 cgttctcgat gtcggtgatg acgtcgcgga agggttcgcg ggtgccgtgg cgggcgggga
    24361 gggggccgca ggtgatgagg gtggcgcggc cggcgagctg ggcgccgcgg gtgccgctga
    24421 acaggggtgt gtcggtgacg ttgatgccgg cgtaaacgaa cgtggcggcc aggcgttcgg
    24481 tgagatcttt gagcaggtcg gcggcctggg cgccggtggt ggtgcgtggg ttgagacggt
    24541 ggatttcgtc gatgaggacg agttggacgc ccgcttgggt gtaggtgtgg cagacggcgt
    24601 cggtgatctg ggtctgggtc atgcgggtgg tggtggggat gccgaggtag cgggcgaatt
    24661 cggtgatgag ggttttcgcg gtggcgccgg gcgggacgag gacgtacgcc acgggtgccg
    24721 tggagtgggc tgatccgggc gggggcgggt ttttgcgggt gtgggcgagg tggcaggtgc
    24781 ggccgacgtt cagcagggcg gtggtttccc ggctgcggcg ggtccggtga cgatgaggga
    24841 gggccgtgcg gtggtctgct ggtggcggcc gaggatcatc agggtgcgga cctgggtggc
    24901 gagggcgctg atggcggggg tgcggatggt gacgaacgcg gagtggtagg cgaggcgttc
    24961 gtcggtgctg cggggcgggt cgcccggctg gggcggggcg ggcgggtcgg tggtggcgaa
    25021 gcggtgccag ccttgccagg tggtcagggg ccaggacggc tcggccgcat cactgttgct
    25081 ggcgccgact ggtgtgctgc ccgcactctg cgggttcggg ttcaccatct gtcggcttcc
    25141 tcgtatgcgt cgtagagccc gaatccggcg gccgcggcgg ggcgggtgtc gtcgtcgggg
    25201 aggtcgtcga ggtcgtcgat gctgtcgtcc tcgccgtgct gcgccgactc gtcggtggcg
    25261 gggccggtgc cgtgttgcgg gggtcgtgcg gcgggaaccg gcagcgtggt ggcgcgggcc
    25321 aggagagctt gttcggtggt ggtggcgtgg ccgctgtgga cgcggcgcat gagctggtcg
    25381 agggcgtcgg cgaggccggc ctcgtgctgc tggctgtcgt cgtggttgtt gtggtgggcg
    25441 tgggtgcgga tgtgctgcca ggtgtggtcg ttgaacggct ggtggacgtg gtcgcggtgg
    25501 atccagggga tttcggtgag gtcgccgtcg gtgaggcgga tccagatctg gcggacgtcg
    25561 tgggggttgt agtggatttc ccatttcccg ccgcggccgg cgacggggga gggctggccg
    25621 cggtaggggg cgaggagatc gtggtcgtag gtgcggtggt ggattgtgat gccggcgggg
    25681 gtgatggcct gccagcgcac gggcagcagt tcgaggtagt cgcggccggt gagcgggacg
    25741 gggacgtgtc cggcgacggc gacgagcgcg gcccacatct ggttcggggt gagggccttt
    25801 ctcggcatca tcgggtgacg caggccttcg tggggccggt ggtgatagtg caccagccac
    25861 tcatcgagca ggtcctgcag ctgggcgacg ctgtagcagg cgtctttctc ggtgtcgggg
    25921 ccgcggcggg tgacgtcgga gccggtgtag ccggtgtagc cgggcaggtg ctggcagaac
    25981 agcgcgttga tggtgccgaa ggtccgctcc acgatgcctt tggcggtggg ggcgtggggc
    26041 ggggcgggct ggacgctgat gccgaggtgt tcgcaggcgg cggtgaacgc ggcggagacg
    26101 aagactttgc cgcggtcgaa gacgatcgtc tcgggcaggg cgacgggccg ggccgccgcg
    26161 ccggccagcc gctcgtcgag tgcggccagc cgctggtggg ggagtgcggg ggcgtggtcc
    26221 atgcgcagga tgtccggcca ggtcggccgg gcggggtggg ggacggccat ctccgccagc
    26281 agcagggccg cgtcgacggc cttggtcgcg ctcgggcaca gcacggcggc gaggatggcg
    26341 cgggtggcga cgtcgacggc gatggtgagt tcgggccggg ccaggcgccc gtcgtcgaag
    26401 agggcgagga cgtccgggcg ggtggtgtcg acctgcactt gctcgcctgg ccgcagcgcc
    26461 gtggcggggg tgaaggcctg cccgtccacg ctcgcgggca cctgcctcac gggcccggag
    26521 ggcagttcac cgggccgggc cagggcggtg acgagccggt acagcgtggc ctgggacggc
    26581 gcgggcaccg tgccggggcc gttccggtct tcaaggatct ggttgatcag cgggaacagg
    26641 ccgttgatgg tgcccttgga gcggccgagg cggcggcgca gcgcttcgcg gacggcggcg
    26701 acgacccgct cgtcagcccg cccggtgggg ctggaagcgc gcgtggtgcg gtggtccaga
    26761 agcccccaca ggccctgctt gcgataagcg agccgcatgc gctgcaccgt ggtgcgcgag
    26821 acccggccga agccgagcgc ggtcagctcc tgggccttgg cctgctcccg ttcggccagc
    26881 gtgtgctgtt cggggtcgta ctgcggccct actactcctt cgctgccaag cccgccgggc
    26941 aggccgcatt cgacttccct gacgtgccgc tgccaggcca gcgccttctc gcgtgccgca
    27001 gcgggggcgg tttcgaacag gccccactgc ggggccgcct gcagcgcatc ggccccaacg
    27061 acggtgaagc cggggtcggt gaacaggtgc ccggcgagca cggcctcgcc cccgccgtcc
    27121 gggccgacga ggtggatgtc ctgccccgag agggcgacca cttgccactt cacgccacgg
    27181 aaccggacgt gagcaccgac cttcacggcc ggcctggcat tgcgccgcgc ggtcacccgg
    27241 catctcccgt ctcggggcag ctcgagcctc gtgagccgac gagggcgtgt tcgtgcagtg
    27301 gcgtctccag gccggccgtc agctgtccgt gccacagggc gtggaagacg acggaaagaa
    27361 cctcgatcgg gtcaccgaca gcttcggcgc cttcgagcag cggccgcggc cgcgcgaacg
    27421 cctccacaac cgcgggtatc aggctgggat ggccggcgtt gcgggggtgg cggtagccgg
    27481 ccagccatta caggttggca gccaggatgt cgtcgagcgg ggggaggcgc cggtaggtcc
    27541 agccgatgtc cgcgcacgcc tgcgccgccg cttcggcggc cttcctcgcg cgttcgccgc
    27601 cggcgtcggg gtggccgggg cagtcggcga gcaacgcggt gccgtcggcg tagcgggcga
    27661 agagctgcgg cacccaggaa cgcacctgcc cgcggggatt acgccacagc agccgcaccg
    27721 gccgccccgc cagaccggtc acgctggggt cgcggtccag gaccatcagc tggacacgca
    27781 tcgcgttcga cccggcggct acatgccgcc cggtcgtcgc cgaccaccac aggcccggcc
    27841 cccagcgccg tcctgggacc accgggaacg ccgacaccgg cggcaagtcc tcgaacgcca
    27901 cggtcatagc ggcatccgcc caccgctgct gcaccgcctg ccccaccggg tcgaggaaca
    27961 ccgcctcgaa cccgccgccc tcggccacgc ctgctcgccc tgcccggctc ctgggccggg
    28021 cagggcctgt gctggtcacc cgcgccagcc aagccgctcc cgcccgcccg aaccgccgtt
    28081 ttcagtattc ctgccacgaa cgagtgccaa ctcaactaac agccgacctg cccgtcgacg
    28141 catcgctctc aaccgcggtt ctcctgcctg cccgccgtca gcatgcggct gagcacctca
    28201 gcgggtatgt ccacccaccg ggccacctct tcaagcggca ccccgccgtt caccgccgcc
    28261 accgctgtgc gtttccaggc gttctcgatc aggccggcac tgtgaccgag gctgcgcagc
    28321 agccgccggg cgacctcggc ggtcggcccg ctctgcaccc cacgcagctg cagcagctgc
    28381 tcctcgacgc tgtcgatcgc gctggtgatc agcctgcgct gttcggcggg caccgcagcc
    28441 cgccacatcg tccccgaacc aggcgctttc ttctccttgc ccagcacccg tagctggccg
    28501 gccatggtcg cggcctggtg ctcctgccgc agccaccacg ggtcgttgtc gtatccgggc
    28561 ggcccgccgg caccgcggcg aaggcggatg acgctgccca tccacgctag gagcggcccg
    28621 ccatggtccg tcgcggccag cggccccagc cacgtacgcc ccagccgctc accgagcctg
    28681 cggcagaaca tcccgtcggc gggcagcgcc cgcgggcgtc cggcaccgct gtccacccac
    28741 accagctcgg ccatggccgg gtccagcagt gcctcggcca ccgccaccac ctccgggaag
    28801 acgaccgcgt cccgccccac catccgccac cgctccagat caccaccggc atcaccgccc
    28861 gcgacctgat gcagacgccg cggccaggcc gtctcccgct cccaaccaaa agcctgctcc
    28921 caccaccggg ccaccaccgc ccgcgccagc gcgaacaccc tctccgctcc gcgccggccc
    28981 gcaccgcccg ccgcgccacc cccacccacc gccgctgcgc cgccaccacc tccggcacgc
    29041 tccgcagatc gaggtgctcc agcggctgat tggcgtccgc gtccagcagc caccgtccat
    29101 gccgtccgca cacccgctcc caccgcgtcg taccgcacca cccgcacgcg aggttcccgt
    29161 acgccgggcc gtgcacaggc ggcagccgaa tcccaccgga ccgaccaccg cgccggccat
    29221 acgccacagc cccaccggat caccagcctc tgcgcgcagc ttggcatctt ccaccgccca
    29281 ggacggcaac gccctcgcca gcacggcttc ctgaacgccg cacatgccga ccagaagctg
    29341 ccgtccggcc gcgttcagca gcacctcggc atcggcacgc gcgccgccgc cctcgtgccc
    29401 aggcgggtag ttgcgccact tccagcagga gcgcaacgcc ttggcttcta tcccgtagcg
    29461 gctcgcgatg cggcagatca gcgacgaggt cgtctctccc tggaggggag cggtccgcag
    29521 gaggcagggg tgatgggtca ctccatcaca ctgccgtggc gccgtcccgc tcgggtactt
    29581 ttgcagctga gagaggcgta cccggg
//
