BGC0000720: tobramycin biosynthetic gene cluster from Streptoalloteichus tenebrarius
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
View antiSMASH-generated output
Download Cluster GenBank file
Download region SVG
Location: 1 - 13,802 nt. (total: 13,802 nt).
This entry is originally from NCBI GenBank AJ579650.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000720
Short description tobramycin biosynthetic gene cluster from Streptoalloteichus tenebrarius
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (None)
Loci
AJ579650.1
via
Compounds
  • tobramycin
Species Streptoalloteichus tenebrarius [taxonomy]
References
Chemical products information
tobramycin Evidence:
Copy SMILES
C18H37N5O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAE22469.1
  • tbmD
 1 - 1176 (-) putative glycosyltransferase
    copy AA seq
    copy Nt seq
    • CAE22470.1
    • tbmC
    		 1280 - 2323 (-) putative dehydrogenase
      copy AA seq
      copy Nt seq
      • CAE22471.1
      • tbmA
      		 2494 - 3654 (-) 2-deoxy-scyllo-inosose synthase
        copy AA seq
        copy Nt seq
        • CAE22472.1
        • tbmB
        		 3684 - 4958 (-) putative 2-deoxy-scyllo-inosose aminotransferase
          copy AA seq
          copy Nt seq
          • CAE22473.1
          • tacA
          		 5186 - 6898 (-) putative carbamoyltransferase
            copy AA seq
            copy Nt seq
            • CAE22474.1
            		 7015 - 8541 (-) hypothetical protein
              copy AA seq
              copy Nt seq
              • CAE22475.1
              		 8582 - 9769 (-) hypothetical protein
                copy AA seq
                copy Nt seq
                • CAE22476.1
                • tbmE
                		 9909 - 11219 (-) putative transport protein
                  copy AA seq
                  copy Nt seq
                  • CAE22477.1
                  • tacD
                  		 11379 - 12398 (-) putative dehydrogenase
                    copy AA seq
                    copy Nt seq
                    • CAE22478.1
                    		 12867 - 13802 (+) hypothetical protein
                      copy AA seq
                      copy Nt seq
                      Biosynthesis information
                      Annotation changelog

                      Entry version: 2

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2019-10-16
                      Migrated from v1.4
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                      Entry version: 1

                      Date
                      Changes
                      Submitters
                      Reviewers
                      2015-06-12
                      Submitted
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                      Similar known gene clusters from MIBiG 4.0
                      Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                      Click on reference genes to show details of similarities to genes within the current region.
                      Click on an accession to open that entry in the MiBIG database.