LOCUS       BGC0000721             43220 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptoalloteichus tenebrarius tobramycin biosynthesis gene cluster
            region, type strain DSM 40477T.
ACCESSION   BGC0000721
VERSION     BGC0000721
KEYWORDS    .
SOURCE      Streptoalloteichus tenebrarius
  ORGANISM  Streptoalloteichus tenebrarius
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Streptoalloteichus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:06:20
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..43220
                     /db_xref="taxon:1933"
                     /mol_type="genomic DNA"
                     /organism="Streptoalloteichus tenebrarius"
                     /strain="type strain: DSM 40477"
                     /type_material="type strain of Streptoalloteichus
                     tenebrarius"
     subregion       1..43220
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000721"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..43220
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="2dos"
                     /region_number="1"
                     /rules="((DOIS or DHQ_synthase or ValA or salQ) and
                     DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             <1..559
                     /codon_start=2
                     /db_xref="UniProtKB/TrEMBL:Q2MF39"
                     /note="ORF SteM07.32"
                     /product="putative acyl-CoA synthetase"
                     /protein_id="CAH18532.1"
                     /transl_table=11
                     /translation="MRSRSRPWPPAWSTRARGGGVVLGVRGDAEVRAAVTRLRYRFGED
                     LTGVLVQPMVEPGRELLVGVHNDGVFGPLVVLGLGGVDTDLVADRTCRLVPLTDRDAAE
                     MLGQLRCAPALLAEQMARRFDAPAVLDVLLRVGRLADLLPEVAELDLNPLVVHGTGAVV
                     VDARVRLEPRPSVDPFLRRLRA"
     CDS             complement(1192..2202)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MF38"
                     /function="putative transport protein"
                     /note="ORF SteK17.1c"
                     /product="putative integral membrane protein"
                     /protein_id="CAH18533.1"
                     /transl_table=11
                     /translation="MAERWRRFRDSPFLPASVLVLILATVAGLFAGSYTYTMANPTPHR
                     IPAGVVGARDDPRGVVFVEMMERALNAALDLRPYDTPEQARDAVEEQKIFGIITVRQDG
                     IELDVSGASGASVAQLLAEAGTRVGQNTGIPVQVRDIKPLQRGDPRGLALFYISLAAVI
                     LGFVGAIQLGVHASGLNPGERIAFTAAYSLLGGFTIAVAVDWVLGALDLPFVESWLILA
                     LTMFTSGMVFTMFNTLIGRWAILPTWGVMVLIGNPSSGGAVSWPLLPSVLGHIGRWLPP
                     GASVNAQHTAVYFRGHQQLFPFLVLAAWAILSCTVFWIWRHRHPGGRPKDGDQDR"
     regulatory      complement(2210..2216)
                     /note="ORF SteK17.1c"
                     /regulatory_class="ribosome_binding_site"
     regulatory      2613..2619
                     /note="ORF SteK17.2"
                     /regulatory_class="ribosome_binding_site"
     CDS             2624..3532
                     /codon_start=1
                     /db_xref="GOA:Q2MF37"
                     /db_xref="InterPro:IPR006015"
                     /db_xref="InterPro:IPR006016"
                     /db_xref="InterPro:IPR014729"
                     /db_xref="UniProtKB/TrEMBL:Q2MF37"
                     /note="ORF SteK17.2"
                     /product="hypothetical protein"
                     /protein_id="CAH18534.1"
                     /transl_table=11
                     /translation="MTNRNVGHPVVVGVGDPTDREVVRWAAAEAVRRGVGLRLVHGYVV
                     MPYTMDQYVPDADTMARRAGEAVMDVAEATAREAFPNLAVTTVLTYGQPELVLLEESAN
                     AALVVVGTHPHSALTETVFGSRAGGLVRDAACPVVAVPPDSAASDRTGPVVVGVDGSPA
                     SQAALGFAFDAASRRGVPLRVAHYWYGELTDVERVEARQDHHILLAESLAGYRERHPDV
                     SVSFEARAADPVEALRAESASACLLVLGTHGLGRLASVLLGSVSRDLVRSARCPVAVVR
                     PQGEKAERPSRLANNAAPRTD"
     CDS             complement(3599..3871)
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MF36"
                     /note="ORF SteK17.3c"
                     /product="putative transcription regulator"
                     /protein_id="CAH18535.1"
                     /transl_table=11
                     /translation="MQAAIGAGTDPTSAEGRELAREWMGSLEQFHGGEPGLWDSLYQDV
                     RGERRADRGELWWVDSGADGVHQAGQRRELLIRSAKRRVEHRSGR"
     regulatory      4508..4515
                     /note="ORF SteK17.4"
                     /regulatory_class="ribosome_binding_site"
     CDS             4520..7480
                     /codon_start=1
                     /db_xref="GOA:Q2MF35"
                     /db_xref="InterPro:IPR006474"
                     /db_xref="InterPro:IPR006483"
                     /db_xref="UniProtKB/TrEMBL:Q2MF35"
                     /function="putative role in DNA-(un)winding"
                     /note="ORF SteK17.4"
                     /product="putative helicase"
                     /protein_id="CAH18536.1"
                     /transl_table=11
                     /translation="MWFGDDPQIVRWLGVLWGKSREKAGGVTNLLMSHLLDTASVGEVI
                     WDHYLAPATRDLLDEVAGGTGRGRLLFAWLCGIHDCGKATPAHQRLWLEGAQAVNRAGL
                     SWNEPMVARFRWRHDRAGGFLLRRALREAGWHADQVAWVWPLVAGHHGLFPSEGQLQEP
                     RQARGELAGHSDWRRAQAAVIEVFTRELGFADLTSVQPVLAPSRATQLHLSGLVVMADW
                     IASDEGHFKGVDDLARVSIEASRERARRAWAELGLRGGWGSRPEPGPEAFEERFAQSPR
                     PSQRLVIEAARTMAEPGIMVVEAPMGEGKTKAALLASESLAARFGADGVFVGMPTQATS
                     DPIFTQVRQWLGCIDPELSAQVALLHGKRMFNKEWRRLLEPSPDGTQERFGGVDEFGMA
                     DEDDAYGLSSSDSRRRERQTPAEWFLGAKRGLLCPFVVGTIDQLLMAATRTKHVMLRMA
                     GLAGKVVVLDEVHAADVYMSRFLVEGLRWLGQARVPVVLLSATLPPQQRQRLIEAYLAG
                     AASREEFALDAPIRAAGYPCVTTAWFDTNRQTPVVTTNETSSWRPDLQVEVEVLAEPIP
                     DRRASREKRRQAQHAADVAVAELLRERLSQGGCALVIRNTVARAQSIYELLRQPAWFGK
                     DVTLLHARLAAQERADRTERCLKLLGARHDNEGEENVQRPRRFVLVATQLAEQSFDVDA
                     DLLVTDLTTIDLLLQRIGRLHRHEKVVRPAGVDRPRVVVTGFDPGVGEAPDILGASQMI
                     YGRYLMMRSAAAVLQVAELTTDDDAKPGNIWAVPSQVPELVARVYEPTCEMVPAEWREA
                     ERVAREEWEQRQRARAEQADMYLLTRLGEHEERTLAGLHFAGPSSVGTERAMEAVVRDG
                     EPSVEVILVVRDGERYRTLAGRPLTHNGDVAPDLLDEVLGATVRLPSKFTDLALEQLRP
                     LAGWYGHPWLRHSLALVLDQAGRAEVDGRPFCLPNGTTLRYDKELGLVEEASTAGR"
     regulatory      7705..7708
                     /note="ORF SteK17.5"
                     /regulatory_class="ribosome_binding_site"
     CDS             7714..9438
                     /codon_start=1
                     /db_xref="InterPro:IPR013381"
                     /db_xref="UniProtKB/TrEMBL:Q2MF34"
                     /note="ORF SteK17.5"
                     /product="hypothetical protein"
                     /protein_id="CAH18537.1"
                     /transl_table=11
                     /translation="MVNLVDDPWLLAYPCEGTEVKEQSLRGLLLDAHQFRDLVVDFPTQ
                     KPALFRQVLLPVVLHALGRPRDTTAWVSLFQQREFTQDQRDRLDRYLDEHRHLFELFDD
                     VNPFAQVANLEAVSGETKGTASLVVTAPTGNNVPLFSSRSDADPLELTPAQAARWLIHA
                     HCWDTAAIKTGAVGDPKVKAGKTTGNPVGPLGQLGFVMPVGSTLYDTLLLNLPSGPAAR
                     SNDRPQWTRRNMNGKVEETHSVALPAWQPRAAEGLLDLWTWQSRRIRLFPEYTDAGVRV
                     SRVIIAAGDRLSQVPDFEPHTAWTLEATGKTTRAKQRKPVPPRRPRRHQPGKAVWRGLD
                     ALLAVSREDREAQTNATGYATSILLDQLKARREEMPLDYPLQIEVFGVVYGNQSAIVED
                     VITDSIPLPLAALSDDSLARAVILEVVSQAEDLANTVNHLSADLRRALGGEPIPWDKGQ
                     RPGEVLLHALDDLVRRLLAGLRAAGENRDLVERGHLAWEQKAFSATAQVAERLLGSVPG
                     SAFLGHTIQSDREQRTYRLATAEAGFWRQLDRILWRAAAERKSREQDGDQTTKAEEA"
     misc_feature    7723..7725
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     protocluster    9173..43220
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[19172:33593]"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      19173..33593
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /neighbourhood="10000"
                     /product="2dos"
                     /protocluster_number="1"
     cand_cluster    9173..43220
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((DOIS or DHQ_synthase or ValA or salQ)
                     and DegT_DnrJ_EryC1 and (LipV or ADSI-DH or cds(ADH_N and
                     ADH_zinc_N)))"
                     /kind="single"
                     /product="2dos"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             9435..10037
                     /codon_start=1
                     /db_xref="InterPro:IPR013382"
                     /db_xref="UniProtKB/TrEMBL:Q2MF33"
                     /note="ORF SteK17.6"
                     /product="hypothetical protein"
                     /protein_id="CAH18538.1"
                     /transl_table=11
                     /translation="MSEKTPSRYWTRFIGADGKWRRAREKKDQMPPGEDLAVLRTGLDR
                     PAGTVFALVPFYTSPIDDHAARRGEVSVEQAAEHVALALFGLHQQGQRSPMHKPGLSVG
                     RALRRLRQTGRFAEEALDRRVAATVNATSVSAFAYRLRGLVDQLRTQGIPLDYDLLLQD
                     VLDWHYSDGRQRVRRRWGLAYFDWSSASTAAAKPTES"
     regulatory      10153..10157
                     /note="ORF SteK17.7"
                     /regulatory_class="ribosome_binding_site"
     CDS             10162..11316
                     /codon_start=1
                     /db_xref="InterPro:IPR010148"
                     /db_xref="UniProtKB/TrEMBL:Q2MF32"
                     /note="ORF SteK17.7, possible translational coupling with
                     ORF SteK17.8 protein"
                     /product="hypothetical protein"
                     /protein_id="CAH18539.1"
                     /transl_table=11
                     /translation="MAQRRYLDVHILQTVPPANLNRDDQGNPKEAYFGGVRRSRVSSQA
                     WKRATRKFFADHENGVPKEDLGVRTRRIVSKLGSLVAERTTAVDAETAGRLAAEVVSTL
                     GITPGKKDSETAYLLFYGRRQLVALADLLASRASELAALEESALKGELKKLPIVDTLGA
                     GHPVDVALFGRMVADVPALNVDAATQVAHALSTHATELEFDYFTAVDDENDDDKDELGA
                     GMIGTVGFNSATLYRYATVGLHQLVDNLGDVAAARRAAGLFVQSFARSMPTGYGNAFAH
                     RTLPHLVAISVRADQPVNLVSAFENPVPATQGIAAASARRLAREQRTAVRNWGDEPLHT
                     GLCHSFGDDRETAAELAEAFGPARTFPELLTELDSHLAEFGENA"
     CDS             11316..12161
                     /codon_start=1
                     /db_xref="InterPro:IPR010147"
                     /db_xref="InterPro:IPR013422"
                     /db_xref="InterPro:IPR021124"
                     /db_xref="UniProtKB/TrEMBL:Q2MF31"
                     /note="ORF SteK17.8"
                     /product="hypothetical protein"
                     /protein_id="CAH18540.1"
                     /transl_table=11
                     /translation="MATPSPSVPSDTGQAVLLLRLAGPLQSWGDRSAFNRRDTRPEPTK
                     SGIIGLLAAAEGRPRGESVADLTALRLGVRVDQAGRLLRDYHTVSDYRGGPLPQAGVSA
                     KGVQKPTSPPKFTHVTTRFYLEDAVFVAGLAGPRDLLERLDSAVRRPAFPLALGRRSCV
                     PTQPVSLGLREGSLRTVLANEPWQVPARAQRRGPRSVDLRVVLEGQEALEGQNVPDGQN
                     VEEDLAYDVPVNFDPRARAFTSRRIQRTWLSVPTAATASATKNDPDVDSGHDPFALLGW
                     "
     CDS             12166..12975
                     /codon_start=1
                     /db_xref="InterPro:IPR010179"
                     /db_xref="UniProtKB/TrEMBL:Q2MF30"
                     /note="ORF SteK17.9"
                     /product="putative transcription regulator"
                     /protein_id="CAH18541.1"
                     /transl_table=11
                     /translation="MPYLSRIRINPLRKASRRMLANPRDLHAAVVNAIPDHPTTERSLW
                     RLDADDPRRPHLVVLTQSRPDWNHLVEQAGWPEADGEHFVIADYNPLLRRLRAGQEFAF
                     RLTANPVQNTRTPDKPTERQAQDDTVTARRRSYRLGHRTAAMQLRWFLTRTLKWGFDVP
                     EAFTAEPAVDIDPHTTPEAETDSSLDQAPRDVRIIARERRSFSKRDGKPPVVLSTVTFQ
                     GRLRVTDPELLTERLLAGIGPGKAYGCGLLTLAPLTKPSTGTGDARG"
     CDS             12959..14059
                     /codon_start=1
                     /db_xref="InterPro:IPR002729"
                     /db_xref="InterPro:IPR019851"
                     /db_xref="UniProtKB/TrEMBL:Q2MF29"
                     /note="ORF SteK17.10"
                     /product="hypothetical protein"
                     /protein_id="CAH18542.1"
                     /transl_table=11
                     /translation="MTRVADIWWKADPLDLHRLVDRVSSIYVERSHIDRDENAVVLINK
                     RETVRVPAALIAVMLLGPGTRITHGAVNLLGDSGTAVCWVGEQGVRLYASGLGPSRGAG
                     LLNRQAWLVSRRQHRLAVARAMYGMRFPGEDVSEMTMRQLRGREGARVRKLYQSHSRRT
                     GVPWNGRVYRPGEPFAAGDDLNRLLSAANAALYGICHAVIVGLGASPGLGFVHTGAATS
                     FVMDIADLYKAEYTIPLAFDLAAKGLVTERDARVALRDRIAENRLLGTIIRDVKALLTP
                     EGAEGEDLDQDLNELWDEEVGSVPGGVNWSSEPIDDIAMSLVDPGMGERHIAVVGPEFD
                     TPSDGLRRPGPASSCSSPHPRDYVGT"
     misc_feature    13292..13294
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS             14020..14286
                     /codon_start=1
                     /db_xref="InterPro:IPR010152"
                     /db_xref="UniProtKB/TrEMBL:Q2MF28"
                     /note="ORF SteK17.11"
                     /product="hypothetical protein"
                     /protein_id="CAH18543.1"
                     /transl_table=11
                     /translation="MLIAAPEGLRGHLTRWMVEVNAGVFVGNPSRRVRDRLWDLLASRI
                     GEGQAVLVEPSDNEQGWAVRTAGRDRWYPVDFDGLVLSARLRR"
     CDS             complement(14972..15142)
                     /codon_start=1
                     /db_xref="PSEUDO:CAH18544.1"
                     /gene="pseudo14971_15142"
                     /note="ORF SteK17.12c"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPSAAPLMPSMAMARPPRAAAPPPTIAGPPVTAQAERPAAAPHHR
                     RGAIPARAGTT"
     CDS             15048..15491
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MF27"
                     /note="ORF SteK17.13, maybe inactive"
                     /product="putative transposase"
                     /protein_id="CAH18545.1"
                     /transl_table=11
                     /translation="MTGGPAIVGGGAAALGGLAMAIDGIKGAAEGIKKNSNRPSNVEPP
                     HEGSRNYDVYDPANKGRRITDIDIIENRILWERKSAAWVQIPEDWVRQQVVKKLNSYIE
                     AQKYMPGCERRRSESDSRRRASKPRRGKKLRTASTRCVEVTLM"
     CDS             15514..15873
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MF26"
                     /note="ORF SteK17.14"
                     /product="hypothetical protein"
                     /protein_id="CAH18546.1"
                     /transl_table=11
                     /translation="MGYVFEVEGETVWSPSLDIGHLFMDIANRLSEDLKQSHGMSLMAS
                     DFIDIDRDAFAAFVRSMLNSSVMTNLTYYVLSRGFLATCLAMLERAGSPVAPQNSEQQD
                     LVAFGKALLGHMPTN"
     CDS             complement(16128..17213)
                     /codon_start=1
                     /db_xref="InterPro:IPR011042"
                     /db_xref="UniProtKB/TrEMBL:Q2MF25"
                     /note="ORF SteK17.15c"
                     /product="hypothetical protein"
                     /protein_id="CAH18547.1"
                     /transl_table=11
                     /translation="MTWLGAVSAREAHLSSSRRPTPCPGSAARTNGHHSWRPHVAGFGK
                     DMIMRRRSLWVEMASVVLAVAAAAAPVAAHRTAEAGAYPSSFSLPAGFRPEGIAIDSDG
                     YAYFGSMGTGAIYKANLATGTGRTLRQGSGSPAIGLKVDSRGRLFVAGGGGGDLKVIDS
                     RTGNLLATYRLATGASFVNDVVLTPDAVWLTDSTQPVLYQLPLGRDGELPAPSAVVRLR
                     LSGDIVYREGTNANGIATTPDGKALLVIQWNTGILFRVDPASGVAKAVDLHGEQLPRGD
                     GLLREGDTLYVVQNRLNTVAVLSLDHSGHSATLTKRVTDPRFDVPTTVASFRDRLYLPN
                     ARFNTTPTPTTPYNVISIPRP"
     gene            17331..17828
                     /gene="tobY"
     CDS             17331..17828
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MF24"
                     /gene="tobY"
                     /note="ORF SteK17.16, putative translational coupling with
                     ORF SteK17.17 protein, TobX, possibly out of the tobramycin
                     biosynthesis gene cluster"
                     /product="putative GTPase, TobY"
                     /protein_id="CAH18548.1"
                     /transl_table=11
                     /translation="MSPGETRQGSGTRVRRTREDERRRRDRWHRGRRRHERERTNVGVA
                     IAGTGVVGVTNARGRTSGSRSLAPRTSASQTPDDEHQYHEHQHHEHRHHERRHYERQYR
                     ERRYDGTNNTSTTDASTRNTSTANDSAPNGLASERGQSTSRGSGLAGTGPPRWEGRTTA
                     VA"
     gene            17829..18488
                     /gene="tobX"
     CDS             17829..18488
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MF23"
                     /function="unknown"
                     /gene="tobX"
                     /note="ORF SteK17.17"
                     /product="TobX protein"
                     /protein_id="CAH18549.1"
                     /transl_table=11
                     /translation="MIMWRGCGRGVPCGRRGRGAAGRGLGYSGSMARMRGVVERPEGLV
                     HQPDLLDEAEERSLLTAVEAMPLHEVRMHGQVARRTVRHFGFDYGYESWRLTPTDPLPE
                     EFWWLRDRCAHLAGLRPESLAQTLIARYPPGATIGWHRDAPMFGPSVVGVSLLSSCLMR
                     FQRRVGEERRVYELELAPRSAYVLSGAARSAWQHSIPPVPELRYSITFRTLRDPAR"
     gene            19173..20192
                     /gene="tobE"
     CDS             19173..20192
                     /NRPS_PKS="Domain: PKS_ER (111-254). E-value: 1.1e-09.
                     Score: 29.7. Matches aSDomain:
                     nrpspksdomains_tobE_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MF22"
                     /db_xref="InterPro:IPR002085"
                     /db_xref="InterPro:IPR011032"
                     /db_xref="InterPro:IPR013149"
                     /db_xref="InterPro:IPR013154"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/Swiss-Prot:Q2MF22"
                     /gene="tobE"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADSI-DH"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_zinc_N"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     ADH_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040:alcohol dehydrogenase (Score: 320.5; E-value:
                     1.8e-97)"
                     /gene_kind="biosynthetic"
                     /note="ORF SteK17.18"
                     /product="putative cyclitol 1-dehydrogenase, TobE"
                     /protein_id="CAH18550.1"
                     /sec_met_domain="ADSI-DH (E-value: 1e-164, bitscore: 538.5,
                     seeds: 6, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_N (E-value: 5.6e-26, bitscore: 81.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.4e-21, bitscore:
                     67.4, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALSFEAPGEAVFGTREVPVPAPGEALIHLGYNSICGSDLSLYR
                     GVWHGFSYPVVPGHEWSGTVVEVNGPGAELVGRDVVGDLTCACGSCAACGRGTPVLCEN
                     LQELGFTRDGACAEYMTIPTGNLHVLPEGLSLRAACQVEPVAVALHAVSTVGVEPGERV
                     AVLGAGGIGLMLMQVARQRGGVITTVGEPVAERRAVAAQLGARTVTTGRPGELAELVAK
                     HPDLTPDVVLEASGYPVAVQEAIEVVRPGGRIGLVGYRVEEVGPMATHHVAVKALTIRG
                     SLGPGGRFPEAIDLLARGEIEVEPLLSHEFALDDHARALDLALRRAEGNVRSFFNLRA"
     aSDomain        19506..19934
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tobE_PKS_ER.1"
                     /evalue="1.10E-09"
                     /label="tobE_PKS_ER.1"
                     /locus_tag="tobE"
                     /protein_end="254"
                     /protein_start="111"
                     /score="29.7"
                     /tool="antismash"
                     /translation="RDGACAEYMTIPTGNLHVLPEGLSLRAACQVEPVAVALHAVSTVG
                     VEPGERVAVLGAGGIGLMLMQVARQRGGVITTVGEPVAERRAVAAQLGARTVTTGRPGE
                     LAELVAKHPDLTPDVVLEASGYPVAVQEAIEVVRPGGRI"
     regulatory      20340..20345
                     /gene="tobT"
                     /regulatory_class="ribosome_binding_site"
     gene            20340..21662
                     /gene="tobT"
     CDS             20352..21662
                     /codon_start=1
                     /db_xref="GOA:Q2MF21"
                     /db_xref="InterPro:IPR011701"
                     /db_xref="InterPro:IPR016196"
                     /db_xref="UniProtKB/TrEMBL:Q2MF21"
                     /function="putative exporter of tobramycin"
                     /gene="tobT"
                     /note="ORF SteK17.19"
                     /product="putative transport protein, TobT"
                     /protein_id="CAH18551.1"
                     /transl_table=11
                     /translation="MSHPAASTDPPTPAGEPSTEDSSSDGASARGTGSRRTTRRLCLFF
                     GLHELVPFFPLYPLLFADHGLSTAGISGLLAFWSVTAFVLEVPSGVLGDMFSRRRLLAL
                     GVAVRACGFGLWVAFPSPWAFAAGFLCWGLCDALTSGTLESLVYDELRAAGATGRYAAV
                     MGSGRAVSLLSTLTAITLAGPLFALGGYPAVGVVSLGSGLACALAALSFSEPPREQVDS
                     EGGGWRWYVATFRAGVSEVRGDRVVLRAVLVAASLHSMTAIDEYFPMLARANGASTTMV
                     PVLVAVTVVCAAVGSGLVGRTAHAPSGALGLALLASAALLAAGALSGLQSGMLAVGVSF
                     GLVQWALVLADTRLQDAITGPARATVTSVVGFGSEVASVGFYLAAGAVSTVTSMSTLVA
                     WFAVPLVLIAVVAFRWLRREPCPTGQVRPEPEPRRRD"
     regulatory      21788..21793
                     /gene="tobB"
                     /regulatory_class="ribosome_binding_site"
     gene            21788..22989
                     /gene="tobB"
     CDS             21802..22989
                     /NRPS_PKS="Domain: Aminotran_3 (42-343). E-value: 1.9e-38.
                     Score: 124.2. Matches aSDomain:
                     nrpspksdomains_tobB_Aminotran_3.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MF20"
                     /db_xref="InterPro:IPR005814"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/TrEMBL:Q2MF20"
                     /function="biosynthesis of tobramycin"
                     /gene="tobB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013:aminotransferase class-III (Score: 270.8;
                     E-value: 3.2e-82)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SteK17.20"
                     /product="putative aminoglycoside 6'-aminotransferase,
                     TobB"
                     /protein_id="CAH18552.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.9e-39, bitscore:
                     126.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTNETIATITDWSRSAEHLRRSHEVTTNPRPDEDGQYPCVLTR
                     GSGARVHDMDGNAYLDLTCSFGTVLIGHAEREVTDAIRACLDEGNLFYTGPSPRRLALA
                     ERLLDWFPWADQALFYRTGSCAVSSVARLSQHVTGRTAVLTSGYHGWHDWHLEAVPEAK
                     LFPSYATEFHDDLDVYRAYLDRHADEIAAVVVTPEPTRHPLEHYRTLRDLAAEAGCLFV
                     LDEVKTGMRAGKGGLSARAGLEPDAVTVSKGLANGHSISAVVGSRRITEGLAEAHVWST
                     YQNEQVGYAAALSTVDFLLREDVAGVVERTGRTVERAFRSAFAERGLPVEVHGWGPMFD
                     LDFSAAEEDLPERLQLALLRHGVFCDVGDDFNLMYRMADHLDELLERVTAAIASV"
     aSDomain        21928..22830
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tobB_Aminotran_3.1"
                     /evalue="1.90E-38"
                     /label="tobB_Aminotran_3.1"
                     /locus_tag="tobB"
                     /protein_end="343"
                     /protein_start="42"
                     /score="124.2"
                     /tool="antismash"
                     /translation="LTRGSGARVHDMDGNAYLDLTCSFGTVLIGHAEREVTDAIRACLD
                     EGNLFYTGPSPRRLALAERLLDWFPWADQALFYRTGSCAVSSVARLSQHVTGRTAVLTS
                     GYHGWHDWHLEAVPEAKLFPSYATEFHDDLDVYRAYLDRHADEIAAVVVTPEPTRHPLE
                     HYRTLRDLAAEAGCLFVLDEVKTGMRAGKGGLSARAGLEPDAVTVSKGLANGHSISAVV
                     GSRRITEGLAEAHVWSTYQNEQVGYAAALSTVDFLLREDVAGVVERTGRTVERAFRSAF
                     AERGLPVEVHGWGPMFDLDF"
     regulatory      23018..23026
                     /gene="tobQ"
                     /regulatory_class="ribosome_binding_site"
     gene            23018..24556
                     /gene="tobQ"
     CDS             23030..24556
                     /codon_start=1
                     /db_xref="GOA:Q2MF19"
                     /db_xref="InterPro:IPR000172"
                     /db_xref="InterPro:IPR007867"
                     /db_xref="UniProtKB/TrEMBL:Q2MF19"
                     /function="biosynthesis of tobramycin"
                     /gene="tobQ"
                     /note="ORF SteK17.21"
                     /product="putative aminoglycoside 6'-dehydrogenase, TobQ"
                     /protein_id="CAH18553.1"
                     /transl_table=11
                     /translation="MLLISADEAARRTYDACVVGSGASGSVAAAVLAERGLSVLVVEQG
                     GPIPPGADVEDHEDPDGWAFARRHGRWTRDGFPWTAMALGGGTVFYAGMSYRYQDSDLA
                     PPSSLLGEADYDHWQVGLADLEPHYEWIEYQLAVAGPSRKRVGDYVFPVYHRPSLPPTP
                     PGLALAEGARALNLTPLPTPVAISGIRDRFGPGCAQATPCTSFSCPTGAKADVVSRVLA
                     PAEGDVSVLVHTRVDRLVASGSHRVDAAEVVDRGTGTRRTLRARRFLVAANAIQSAALL
                     LRSTSRLEPDGLGNGNGLVGRHLAMKNSVYVRGVVPRRLPGYTPLRHRYSSVCVLDYLT
                     GEEFPDGVGGLIHEANPWEPAAEREAERGTVLQVECLLGDRPQARNRVRLSRTRDRDGF
                     PRIVLDYEPHPADLTRLAVLSERATDILTKAGAIDVREVDTAYELGSAHLHGTLRSGRD
                     PRTSVTDPFGRLHGYDNVWAVDGATFPFAGNPNPTLTIQANAHRIASAID"
     regulatory      24661..24665
                     /gene="tobZ"
                     /regulatory_class="ribosome_binding_site"
     gene            24661..26385
                     /gene="tobZ"
     CDS             24673..26385
                     /codon_start=1
                     /db_xref="GOA:Q2MF18"
                     /db_xref="InterPro:IPR003696"
                     /db_xref="UniProtKB/TrEMBL:Q2MF18"
                     /function="biosynthesis of nebramycin factors no. 4 and 5"
                     /gene="tobZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Carbam_trans_N"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SteK17.22"
                     /product="putative 6''-carbamoyltransferase, TobZ"
                     /protein_id="CAH18554.1"
                     /sec_met_domain="Carbam_trans_N (E-value: 1.3e-29,
                     bitscore: 94.9, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLGLNGWPRDFHDASAALLVDGRIAAFAEEERFTRKKHGYNTA
                     PVQAAAFCLAQAGLTVDDLDAVAFGWDLPAMYRERLGGWPHSDSEALDILLPRDVFPRR
                     TDPPLHFVQHHLAHAASAYYFSGEDRGAVLIVDGQGEEECVTLAHAEGGKITVLDTVPG
                     AWSLGFFYEHVSEYTGLGGDNPGKLMGLAAHGTTVDETLSAFAFDSDGYRLNLIDPQAR
                     DPEDWDEYSVTERAWFAHLERIYRLPPNEFVRRYDPAKGRVVRDTRRDPYEYRDLAATA
                     QAALERAVFGLADSVLARTGERTLFVAGGVGLNATMNGKLLTRSTVDKMFVPPVASDIG
                     VSLGAAAAVAVELGDRIAPMGDTAAWGPEFSPDQVRAALDRTGLAYREPANLEREVAAL
                     IASGKVVGWAQGRGEVGPRALGQRSLLGSAHSPTMRDHINLRVKDREWWRPFAPSMLRS
                     VSDQVLEVDADFPYMIMTTKVRAAYAERLPSVVHEDWSTRPQTVTEASNPRYHRMLTEL
                     GDLVGDPVCLNTSFNDRGEPIVSSPADALLTFSRLPIDALAVGPYLVTKDLRH"
     regulatory      26594..26601
                     /gene="tobS1"
                     /regulatory_class="ribosome_binding_site"
     gene            26594..27887
                     /gene="tobS1"
     CDS             26613..27887
                     /codon_start=1
                     /db_xref="GOA:Q2MF17"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/Swiss-Prot:Q2MF17"
                     /function="also putative ketoaminocyclitol aminotransferase
                     II function"
                     /function="biosynthesis of tobramycin"
                     /gene="tobS1"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     400.3; E-value: 1.4e-121)"
                     /gene_kind="biosynthetic"
                     /note="ORF SteK17.23"
                     /product="putative 2-deoxy-scyllo-inosose aminotransferase,
                     TobS1"
                     /protein_id="CAH18555.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 8.9e-108,
                     bitscore: 351.9, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVHLAINNGTPVRTRPWPVWPQPARGALDALERVLRSGRWAISG
                     PYRGIESAERRFARDFAAYNGVAHCVPAASGTASLMLALESCGVGVGDEVIAPGLSWVA
                     SASTIVGVNAVPVLVDIDPRTLCLDPAAVEAAITPATKAVVVVHLYSAVADLDALRAVA
                     DRHGLPLIEDCAQAHGAEHRGRKVGSVGDVGTFSMQHSKVLTSGEGGAAITNSAELARR
                     MEHLRADGRCYPDTAPAPGRMELVETGELMGSNRCLSEFQAAVLVEQLRELDEQNALRR
                     RNAELLNTLLAEQGLRPQATSPGTTSRTYYVYAAELPDDAFVGLPITTVTEALTAELGF
                     PISPAYAPLHTNRLYAPASRRRFALGEEHEKRIDPARFHLPVCERLTRRLITFHHAALL
                     GDESDMHDIAAAVAKVLRHHGELRA"
     regulatory      27905..27911
                     /gene="tobC"
                     /regulatory_class="ribosome_binding_site"
     gene            27905..29077
                     /gene="tobC"
     CDS             27917..29077
                     /codon_start=1
                     /db_xref="GOA:Q2MF16"
                     /db_xref="InterPro:IPR002658"
                     /db_xref="InterPro:IPR016303"
                     /db_xref="UniProtKB/Swiss-Prot:Q2MF16"
                     /function="biosynthesis of tobramycin"
                     /gene="tobC"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DHQ_synthase"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DOIS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183:3-dehydroquinate synthase (Score: 368.3; E-value:
                     5.6e-112)"
                     /gene_kind="biosynthetic"
                     /note="ORF SteK17.24"
                     /product="putative 2-deoxy-scyllo-inosose synthase, TobC"
                     /protein_id="CAH18556.1"
                     /sec_met_domain="DOIS (E-value: 3.9e-178, bitscore: 583.0,
                     seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 2.9e-71, bitscore:
                     230.9, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTTTITMGDVQYPYRLGTGCVDGIVTRLGELEASHYLVLCDATV
                     AELYGHDLAARLRRSAGPASVLTHPAGEEHKGLGTLDTLADAALHAGVDRRGVVVALGG
                     GVTGNIAGLLAALLFRGIRLVHVPTTVVAMLDSVLSLKQAVNAQVGKNLVGTFYPPVEV
                     LADTAMLGTLPVREIRSGLCEVVKNALAIRPSMIDFLAAELRPDGRYADDVLRWMIDES
                     VAAKAQVTEHDKYERREGLVLEYGHTVGHALEHASHGAVSHGAGVGVGMVAAAEVARRL
                     GHVDADLVELHRELVGKVGVATTLPADVPTEEITYRLGFDNKRGYQPLPADHYAMVLLA
                     DVGQPLYQDGLPLTPAPRALVDEVVRELADAPSRIGASVGSAGGAS"
     gene            29248..30291
                     /gene="tobD2"
     CDS             29248..30291
                     /codon_start=1
                     /db_xref="GOA:Q2MF15"
                     /db_xref="InterPro:IPR000683"
                     /db_xref="InterPro:IPR004104"
                     /db_xref="InterPro:IPR016040"
                     /db_xref="UniProtKB/TrEMBL:Q2MF15"
                     /function="biosynthesis of tobramycin"
                     /gene="tobD2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 243.8; E-value: 5.1e-74)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SteK17.25"
                     /product="putative hexose-3''-dehydrogenase, TobD2"
                     /protein_id="CAH18557.1"
                     /transl_table=11
                     /translation="MGGVHAEVFAEHPRARLAAVCDLDRGAARELAGRFAVETVTDDLD
                     SVLSDDRIGLVVVTTPNALHAEQAARALRAGRHVLVEKPLALTSDEIRGLLRLADERGL
                     VLAHGSNFVHSPKFRRVRELVADADAFGRPHLARVVVRNGGPDSGWCLDPALAGGGVLL
                     DLGCHAVEICRWLLGGAEVRAVTARSQRVRPRAGRVEDQATLLLEFADGALGQCDVSWA
                     CPGGEEITTEVLGTSGRAGADLWAGMGVHAFSERGFASVWEPNQGWVRPEWEWVRASGY
                     THQDHAVVEAVLDGTPLPHSAVEAWTSARVLEAAAESAATGRTVELAPSPNGHPVPDAV
                     RGGDRVH"
     regulatory      30290..30297
                     /gene="tobM2"
                     /regulatory_class="ribosome_binding_site"
     gene            order(30290..30297,30308..31570)
                     /gene="tobM2"
     CDS             30308..31570
                     /codon_start=1
                     /db_xref="GOA:Q2MF14"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q2MF14"
                     /function="biosynthesis of tobramycin"
                     /gene="tobM2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 308.5;
                     E-value: 1.2e-93)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SteK17.26, possible translational coupling with
                     ORF SteK17.27 protein, TobD"
                     /product="putative 6-glucosyltransferase, TobM2"
                     /protein_id="CAH18558.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.1e-45,
                     bitscore: 146.6, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRRGGVLALTPFFLYPEYQDCWSARFDSMGGMHLLVRALVEEMA
                     GRGVPHRVLTMAPPGVPRDLAIARNVTVHARRLPVLPIPSQLEGYFGLVGAWAKGSLLW
                     VLRNRRRLRREISLVHAHCDGSGSAPFYGWLIARALGVPLVAQIHSSRFLSQHPTTLWE
                     RVTDPAAKWAERFTVRNAAAVLMLTEKARTEMRDAAALDPRRVHRLAYLASDRFAEGDT
                     EERRTEIRRRFGLDTGQPVVLYVGRIAAEKGVEFFVEAAAELRRRGRNCRFLVAGDGPT
                     RQEIEKLAEDRGVADRITITGFLPHELIPSVMALSQLVVLPSRYEELGIVILECMSMRR
                     PIVAHDVNGVHKLIEHGRTGLLVPPFDTPAMADAIEALLDDPELRERIAETAAPLPSAK
                     YSLTTAADQLTDIYRELGVCV"
     gene            31561..32346
                     /gene="tobN"
     CDS             31561..32346
                     /codon_start=1
                     /db_xref="InterPro:IPR003737"
                     /db_xref="UniProtKB/TrEMBL:Q2MF13"
                     /function="possibly involved in biosynthesis of tobramycin"
                     /gene="tobN"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SteK17.27, possible translational coupling with
                     ORF SteK17.28 protein, TobS2, member of LmbE-protein
                     family"
                     /product="putative amidase, TobN"
                     /protein_id="CAH18559.1"
                     /sec_met_domain="PIG-L (E-value: 4.9e-14, bitscore: 44.5,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLTLLAPHPDDIALSVGGWLAGVGPRLRASGWRLDLVTVFSRSV
                     YAPFAGDDARDEDAVSLLRLAEDLRFARSQRLRPSALGLPDCSCLGMDDESELVAPTAT
                     DPRKSIVDDVVARAVAGSAVVVAPLAVGGHVDHRLARDAVAEALGEIPCLWYEDLPYAL
                     DDAVPTPRSPVDGRTLRPWPVRITAQLPAKRAALACYRSQMSDTDIGEVLNYRPDGGAE
                     PVERLWTSADLPPDLAGTLGLVDQDTPSPHLIPVNLEDK"
     gene            32343..33593
                     /gene="tobS2"
     CDS             32343..33593
                     /NRPS_PKS="Domain: Aminotran_1_2 (46-177). E-value:
                     2.8e-09. Score: 28.4. Matches aSDomain:
                     nrpspksdomains_tobS2_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MF12"
                     /db_xref="InterPro:IPR000653"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015422"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/Swiss-Prot:Q2MF12"
                     /function="biosynthesis of tobramycin"
                     /gene="tobS2"
                     /gene_functions="biosynthetic (rule-based-clusters) 2dos:
                     DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     367.2; E-value: 1.6e-111)"
                     /gene_kind="biosynthetic"
                     /note="ORF SteK17.28"
                     /product="putative L-glutamine:hexose-3''-aminotransferase,
                     TobS2"
                     /protein_id="CAH18560.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.8e-100,
                     bitscore: 327.9, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.9e-09, bitscore:
                     28.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSELALFGGTPVRTEPFPDGPRFRERDLERIREVLESGSLGGIP
                     FPNRTHRAFAEQFCGRLGARHGVLVANGTVSLSVALRALGVHAGDEVITTGYTWMGTAA
                     SIVHINAVPVLVDIDPNTWCIDPAAVEAAITPRTRAIVPVHLANQIADLDALLEIARKH
                     DLVVLEDCAHAHFAEWRGRCVGTHGDAGSFSFESSKIMTSGEGGFLVSGDETTHHRAMS
                     LVNCGRKEEGYDSFEGRMLGWNNRATELQAAFLIGQVEQHDELHAQRKSNVELLTKGLT
                     EIGGFTPVGDDDPRVTRRQYYEVLYRFDPEQWAGVHRDRVLEALLAEGVEFEGITFYPP
                     LHRDSLFTVSAEDWPMIRDRYGDRMGPEDFHLPVSERAAYDESVWVHHSLLTGPATDVD
                     QILEAVAKVRRNVDALR"
     aSDomain        32481..32873
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tobS2_Aminotran_1_2.1"
                     /evalue="2.80E-09"
                     /label="tobS2_Aminotran_1_2.1"
                     /locus_tag="tobS2"
                     /protein_end="177"
                     /protein_start="46"
                     /score="28.4"
                     /tool="antismash"
                     /translation="PNRTHRAFAEQFCGRLGARHGVLVANGTVSLSVALRALGVHAGDE
                     VITTGYTWMGTAASIVHINAVPVLVDIDPNTWCIDPAAVEAAITPRTRAIVPVHLANQI
                     ADLDALLEIARKHDLVVLEDCAHAHFA"
     regulatory      33643..33647
                     /note="ORF SteK17.29"
                     /regulatory_class="ribosome_binding_site"
     CDS             33652..34023
                     /codon_start=1
                     /db_xref="UniProtKB/TrEMBL:Q2MF11"
                     /note="ORF SteK17.29, possibly non-functional, fragmentary
                     ORF"
                     /product="putative retrotransposon protein"
                     /protein_id="CAH18561.1"
                     /transl_table=11
                     /translation="MNPTRQDLRTDPPRHGDGLHDAVDLLRRAMALVLAHTDQWDALGA
                     ASVAAVEAALEMVAANAGTATGNGAAPAPAGPRGRRTEDIQRAVDSARAAVVASTFALR
                     EAADEERRRRQTPPPRAGA"
     regulatory      34236..34242
                     /gene="tobM1"
                     /regulatory_class="ribosome_binding_site"
     gene            34236..35502
                     /gene="tobM1"
     CDS             34252..35502
                     /codon_start=1
                     /db_xref="GOA:Q2MF10"
                     /db_xref="InterPro:IPR001296"
                     /db_xref="UniProtKB/TrEMBL:Q2MF10"
                     /function="biosynthesis of tobramycin"
                     /gene="tobM1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 277.8;
                     E-value: 2.7e-84)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SteK17.30"
                     /product="putative aminoglycoside
                     4-glucosaminyltransferase, TobM1"
                     /protein_id="CAH18562.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 4.6e-34,
                     bitscore: 108.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLRLTPFFHHDCVTSWPAEFDAVGGMQLQILRLSRELARRGVR
                     QQVLTLGFPGLPRVRVDSPNLVVRITRAPLPRLRSELTGLVGLNQAWLVAALAACVRLR
                     RTWRPDLVHVHADGQLWALLAGPAASRVLGVPYCVTLHCSRLSVYQPMSWIDQLQHRLV
                     VAAEKWALRGASGVSTLTDRTASVVASALGVGAEDVDVVPDSVDTSSTVDRAEGRVLLE
                     KLGVPSDHEAVGYVGRVAHEKGWPDLVRVAGALSDRKATFLVVGDGPQSGRMRDEVAAA
                     GLSDRFLFTGFLPHHDIPAVMAGLDVLVMPSRHEELGGSALEAMLAGTPVAAYAVGGLR
                     DTVGHVTPSLLVPPGDVTALAEAVRGVLDDPRPHRDQVAAGRSWLTDLFDGGAAARRVI
                     AHYERVLSGTARLRPQE"
     CDS             complement(36571..37803)
                     /codon_start=1
                     /db_xref="GOA:Q2MF09"
                     /db_xref="InterPro:IPR005479"
                     /db_xref="InterPro:IPR011761"
                     /db_xref="InterPro:IPR013815"
                     /db_xref="InterPro:IPR013816"
                     /db_xref="UniProtKB/TrEMBL:Q2MF09"
                     /gene="tobL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 98.9; E-value: 5.8e-30)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SteK17.31c, possibly out of the tobramycin
                     biosynthesis gene cluster"
                     /product="putative carbamoyl-phosphate synthase, TobL"
                     /protein_id="CAH18563.1"
                     /sec_met_domain="ATP-grasp (E-value: 2.7e-07, bitscore:
                     21.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNELVVFVNVRRTHLERGAVFEAAHRLGYGVALLADAVPEGLPR
                     GIVRTVVRLDTRDEAAVHAAVDEIAAEHRIAAVLGWSERDVTTVSGIAQRLGLPGVSPG
                     AARLARNKYLMREAVAEHHPHLVPRFARVTDWSDLSRAVELVGFPAVLKPTSSSGSRGI
                     FVIDGPAGLRPAFDRLMDLTATTETRHELIYEEFLHGTEHSVEGFVHCGQIHVVGVIDK
                     RTTEPFRLELAHLHPSALPADRLDAVHRLTADVVSALGLDDCAFHLECMVAPDGGVRLV
                     EIGARGGGDFIASHLVGLATGRSFVENAIRVATGRPPLDAAGPPLWACVRKILTDRVGT
                     LTGYAGLDDACRVPGVRHLVIEQPVGAEITQPPVDFKSCILGAVITVGDSAEAAEGSAE
                     QAAALVRADIS"
     gene            complement(36571..37814)
                     /gene="tobL"
     misc_feature    complement(37675..37677)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     regulatory      complement(37809..37814)
                     /gene="tobL"
                     /regulatory_class="ribosome_binding_site"
     gene            complement(37872..38852)
                     /gene="tobU"
     CDS             complement(37872..38852)
                     /codon_start=1
                     /db_xref="GOA:Q2MF08"
                     /db_xref="InterPro:IPR000620"
                     /db_xref="UniProtKB/TrEMBL:Q2MF08"
                     /gene="tobU"
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 116.7; E-value: 2.1e-35)"
                     /gene_kind="transport"
                     /note="ORF SteK17.32c, possibly out of the tobramycin
                     biosynthesis gene cluster, member of the permeases of the
                     drug-metabolite transporter (DMT) superfamily"
                     /product="putative transport protein, TobU"
                     /protein_id="CAH18564.1"
                     /transl_table=11
                     /translation="MVSRSRPGSLALGLALGAAGAVAMGSSAPALKLLARTELSPVNVI
                     QVRTVVGALALLTAALLLRRGRLRIRPGDWWLVVLYGVVTLAVNQVVYTVALSRIPVGI
                     ALLLEYLSPVLVALWVRFVQRKHLSGLLWVGIAVALCGLALISQVWTSFALDGVGVLFG
                     LLAAATLAGRFLLAERGLRDYDPLVMATWGTCLGAVALTLAGVVAPFPFHVLGEVSAVG
                     GVDVPVWLLALWVGLVGMAGAILLSVTAQRSIPPTSASLVATLEIVVGGVLAMLVLGER
                     LGAVQMVGSVVMLAGIVIAQVAVARRNTAAVAATAPELLPTRSAS"
     gene            complement(38852..39970)
                     /gene="tobA"
     CDS             complement(38852..39970)
                     /NRPS_PKS="Domain: Aminotran_1_2 (46-331). E-value:
                     1.9e-24. Score: 78.3. Matches aSDomain:
                     nrpspksdomains_tobA_Aminotran_1_2.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MF07"
                     /db_xref="InterPro:IPR004839"
                     /db_xref="InterPro:IPR015421"
                     /db_xref="InterPro:IPR015424"
                     /db_xref="UniProtKB/TrEMBL:Q2MF07"
                     /gene="tobA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 238.3; E-value:
                     2.4e-72)"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SteK17.33c, possibly out of tobramycin
                     biosynthesis gene cluster"
                     /product="putative aspartate aminotransferase, TobA"
                     /protein_id="CAH18565.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.3e-24, bitscore:
                     78.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADHTSELVPFTRGVPPAEVLLVDELAKLTTQVLEESPVAVFQYA
                     PIGRNRGDERLRAELGRHHGVDPDRIFVSNGSLQVLDLLARHLIGRFGRSVLTEAPTYD
                     RARQIFERHGGQVTGVALRGDGADLDQLRDLVARHTPAFFYTIPDFQNPAGVCMSEEKR
                     RALVGLARQYGFLIVEDTPYRRLRYRGAAAPTLAELAPDRVLTISSLSKVLSPGLRVGY
                     AIGDADTMVQLAELAEGTYLTASPLAQAVAARALEDGLVERSIQRAVTFLAPRHDAAVE
                     AAREAFGDGLLSEPGGGYFVSALVRSDLTEAEFLAAAERAGVRLSRGSAFFPDERLPAG
                     SLFLRLPFQALSLEAFRRGARALADVVARRVR"
     aSDomain        complement(38978..39832)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tobA_Aminotran_1_2.1"
                     /evalue="1.90E-24"
                     /label="tobA_Aminotran_1_2.1"
                     /locus_tag="tobA"
                     /protein_end="331"
                     /protein_start="46"
                     /score="78.3"
                     /tool="antismash"
                     /translation="IGRNRGDERLRAELGRHHGVDPDRIFVSNGSLQVLDLLARHLIGR
                     FGRSVLTEAPTYDRARQIFERHGGQVTGVALRGDGADLDQLRDLVARHTPAFFYTIPDF
                     QNPAGVCMSEEKRRALVGLARQYGFLIVEDTPYRRLRYRGAAAPTLAELAPDRVLTISS
                     LSKVLSPGLRVGYAIGDADTMVQLAELAEGTYLTASPLAQAVAARALEDGLVERSIQRA
                     VTFLAPRHDAAVEAAREAFGDGLLSEPGGGYFVSALVRSDLTEAEFLAAAERAGVRLSR
                     GSAF"
     CDS             complement(40080..41156)
                     /codon_start=1
                     /db_xref="GOA:Q2MF06"
                     /db_xref="InterPro:IPR000262"
                     /db_xref="InterPro:IPR008259"
                     /db_xref="InterPro:IPR012133"
                     /db_xref="InterPro:IPR013785"
                     /db_xref="UniProtKB/TrEMBL:Q2MF06"
                     /gene="tobD3"
                     /note="ORF SteK17.34c, possibly out of the tobramycin
                     biosynthesis gene cluster"
                     /product="putative L-lactate dehydrogenase, TobD3"
                     /protein_id="CAH18566.1"
                     /transl_table=11
                     /translation="MTIPDFERSWRERTDRAIWEYVAGGAGTHRTIDDNAAAYDRIWLL
                     PRGVRTSTGEPDTSVTLLGRTVSSPVVLAPTSPQRLVHPDAELATARAARARDVLSIVS
                     TDTHHAFPEIAAEAPGLSWFQLYGYRSREDVAATVELAERGGATALVVTVDASYSARRI
                     STRRAGFRLPDDVDYGTLRALGVLDGAAPASGRLDRLPVTWDDLAWIRSLTTLPVLVKG
                     VLRPEDALRCVELGAEGVIVSNHGGRQLDGALPSLVALDRIARVLPRGRTLLVDGGVRS
                     GVDVVKALALGAHAVCVGRPYLWGLGLNGQKGVEQVLDVFDVEVRDALRQLGVSSVSEL
                     GGQFVARAPGFLPDESLR"
     gene            complement(40080..41180)
                     /gene="tobD3"
     regulatory      complement(41174..41180)
                     /gene="tobD3"
                     /regulatory_class="ribosome_binding_site"
     CDS             complement(41186..42169)
                     /NRPS_PKS="Domain: TauD (88-298). E-value: 3.8e-24. Score:
                     77.7. Matches aSDomain: nrpspksdomains_tobO_TauD.1"
                     /codon_start=1
                     /db_xref="GOA:Q2MF05"
                     /db_xref="InterPro:IPR003819"
                     /db_xref="InterPro:IPR014503"
                     /db_xref="UniProtKB/TrEMBL:Q2MF05"
                     /gene="tobO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /note="ORF SteK17.35c, possibly out of the tobramycin
                     biosynthesis gene cluster"
                     /product="putative oxygenase, TobO"
                     /protein_id="CAH18567.1"
                     /sec_met_domain="TauD (E-value: 2.5e-24, bitscore: 77.7,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSALTIPLYHVPEDERIRLWEHSERVAGGRGQEGAAPESARPDL
                     GGLDAAIRGFAADAGVDGFLLLRGLEIGEIPPTHTDGRPTTLDAHPTSATLQLVAETLG
                     TMVGYADEKDGRLVHEVQPVPGDETRIENSGSVAFDFHTENVHHPLRPDYLGLLCLRQD
                     HLGVAATRVASVRHALALLDDDTVATLRGLWFLSNYPTSFTRAAGGELPPVGPHPVIFG
                     DEDRPFLRFNSHNTFSTTPAGRAALVRLTQALEEVCHDVVLEPGDCVIVDNNVAAHGRS
                     GFTPRYDGQDRWLRRFYSVRAIPRTVQHMMGGGRVVPSMATIRGLW"
     gene            complement(41186..42180)
                     /gene="tobO"
     aSDomain        complement(41276..41905)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_tobO_TauD.1"
                     /evalue="3.80E-24"
                     /label="tobO_TauD.1"
                     /locus_tag="tobO"
                     /protein_end="298"
                     /protein_start="88"
                     /score="77.7"
                     /tool="antismash"
                     /translation="AHPTSATLQLVAETLGTMVGYADEKDGRLVHEVQPVPGDETRIEN
                     SGSVAFDFHTENVHHPLRPDYLGLLCLRQDHLGVAATRVASVRHALALLDDDTVATLRG
                     LWFLSNYPTSFTRAAGGELPPVGPHPVIFGDEDRPFLRFNSHNTFSTTPAGRAALVRLT
                     QALEEVCHDVVLEPGDCVIVDNNVAAHGRSGFTPRYDGQDRWLRRFY"
     regulatory      complement(42174..42180)
                     /gene="tobO"
                     /regulatory_class="ribosome_binding_site"
     gene            42393..42884
                     /gene="tobR"
     CDS             42393..42884
                     /codon_start=1
                     /db_xref="GOA:Q2MF04"
                     /db_xref="InterPro:IPR000485"
                     /db_xref="InterPro:IPR011008"
                     /db_xref="InterPro:IPR011991"
                     /db_xref="InterPro:IPR019887"
                     /db_xref="InterPro:IPR019888"
                     /db_xref="UniProtKB/TrEMBL:Q2MF04"
                     /gene="tobR"
                     /gene_functions="regulatory (smcogs) SMCOG1120:AsnC family
                     transcriptional regulator (Score: 129.5; E-value: 1.2e-39)"
                     /gene_kind="regulatory"
                     /note="ORF SteK17.36, possibly out of the tobramycin
                     biosynthesis gene cluster"
                     /product="putative transcriptional regulator, TobR"
                     /protein_id="CAH18568.1"
                     /transl_table=11
                     /translation="MPRDGKVLDDVDHRLLALLQEDSGRTLGALGELVGLSASAVQRRV
                     ERYRASGILARYVAVLEPRRGLDVLLAICLVTLERESGHAHEEFRRRLLAAPEVQQLYN
                     VSGDSDYVVVLATTGMAHHREVADRLLKDAPNVRRYSTLFVLDPVRTGSALPTRREGED
                     "
ORIGIN
        1 cggccggtcg cggtcaaggc cgtggccacc ggcctggtcc acaagagcaa ggggcggggg
       61 agtggtgctc ggcgtgcggg gcgacgccga ggtgcgcgcc gccgtgaccc ggctgcgcta
      121 ccggttcggc gaggacctga ccggggtgtt ggtgcagccc atggtggagc ccggccggga
      181 actgctggtg ggcgtgcaca acgacggtgt gttcggcccg ctggtcgtcc tggggttggg
      241 cggggtggac accgatctgg tggccgaccg cacctgccga ctggttccgc tcaccgaccg
      301 ggacgccgcc gagatgctcg ggcagctccg gtgcgcgccc gccctgctgg ccgagcagat
      361 ggcccgccgg ttcgacgctc cggccgtgct cgacgtgctg ttgcgggtgg gacggctggc
      421 cgacctgctc cccgaggtgg ccgagctgga cctcaacccg ctcgtcgtgc acggcaccgg
      481 ggccgtggtg gtcgacgcca gggtccgcct cgaaccccgc ccgtccgtcg acccgttcct
      541 gcggcgcctc cgggcgtgac cgagaaccat ccagacgggc ggcggggtgt gacctgcggg
      601 aacggtgtgg gccgtgaaag aggtgtcgac agccggttct ggcggtggtc gcgcaccgga
      661 accctgacca ctctggcgag gcgggcacgg gtgatcgccg agatcattaa cgaactcgac
      721 cgggaggtct cggtcgactt cgcatcgtgc gcgcgtgtga cgggcatggt cgaccactgt
      781 cggtggtgtt cacgggcggc ggtgtcagcg acaccaccct gttcgagggt gttgtggccg
      841 gtatccgggt cacccgcgcg gtcgggcgct ggcgtgccat gtcgggcggg tgttcgcgga
      901 caagggctac tccagccgtg ccgaccgtgg acacctggcc cgacgcggca tcagatcgac
      961 aagcaacaca tcgtggtcga gcgccgcttc aaccagcttc agcaagatcg tgcgatcacc
     1021 cgtcatggca ggacggccct gtcctgtcga gctgtgatcg atctcgccac cctcacgatc
     1081 tgcccttttg ggtgagtgga cgcggtgtga cgtgctcctg gccgaccgcc gtgttgggtg
     1141 ccaggccacg tccgttgtgg aacggttgac cgggaggcga cacccggcga ctcagcggtc
     1201 ctgatccccg tccttggggc ggcctcccgg gtgacggtgc cgccagatcc agaacaccgt
     1261 gcaggacagg atcgcccatg cggcgagcac caggaacggg aagagctgct ggtggccccg
     1321 gaagtagacg gcggtgtgct gggcgttgac ggacgcgccc ggcggaagcc agcggccgat
     1381 gtggccgagc accgacggca gcaggggcca ggacaccgcg ccgccggagg acgggttgcc
     1441 gatcagcacc atcacgcccc acgtcggcag gatcgcccac cgcccgatga gggtgttgaa
     1501 catcgtgaag accatgcccg aggtgaacat cgtcaacgcg aggatcagcc aggactcgac
     1561 gaagggcagg tcgagggcgc cgagcaccca gtcgacggct acggcgatgg tgaagccgcc
     1621 gagcagggag tacgcggcgg tgaaggcgat gcgttccccc gggttgagcc cgctcgcgtg
     1681 gacgccgagc tggatggccc cgacgaagcc gaggatcacg gcggccaacg agatgtagaa
     1741 caacgccagg ccccgggggt cgccccgctg gagcggcttg atgtccctga cctggaccgg
     1801 gatgccggtg ttctgcccga ccctggtccc ggcctcggcg aggagctggg ccaccgacgc
     1861 cccggacgct cccgacacgt ccagctcgat cccgtcctga cgcacggtga tgatcccgaa
     1921 gatcttctgc tcctccaccg cgtcgcgggc ctgctccggg gtgtcgtagg ggcggaggtc
     1981 gagcgcggcg ttcagcgcgc gctccatcat ctcgacgaag accacgccgc gggggtcgtc
     2041 ccgcgctccg acgacgccgg cggggatgcg gtgcggcgtg gggttggcca tggtgtaggt
     2101 gtaggagccc gcgaacaggc cggccacggt ggcgaggatc agcacgagca ccgacgccgg
     2161 gaggaacggc gagtcccgga acctgcgcca gcgctcggcc atcgcgccac ctccctggcg
     2221 cgggtcgcgg tcgctccggc tgccggactg atcggccatg ggggcaggct tacaccatcg
     2281 ccgacgcggg aaaccggacc gaccagccga gcgtcggcgc ggagtcggac ttccacccga
     2341 tgggggcgga cgccgtccga cgcgctcggt caccgtcggc tgccgtcggg cgggagcggg
     2401 tgtggccggg aaggcagggt cttgggtccc gacgtcgggc gggagcgggt gtggccggga
     2461 agacagggtc tttagtcccg acctgcgggc ctttcgccgc tgctcgcctg ccgtcgaacc
     2521 cacctactgt cgagggacag accgctcgcg ggagcgcggt gaccggcggc gcgtacgccc
     2581 gtcggcccgc gcgggcgcgg cggacgggca ccaggaggac gagatgacga acaggaacgt
     2641 gggccacccc gtcgtggtgg gagtcggcga cccgaccgac cgggaggtcg tgcggtgggc
     2701 cgccgccgag gcggtccgca ggggcgtcgg gctccgtctg gtgcacggct acgtcgtgat
     2761 gccgtacacc atggaccagt acgtgcccga cgcggacacg atggcgcggc gcgctggcga
     2821 ggccgtcatg gacgtggcgg aggcaaccgc gcgggaggcc ttccccaacc tcgcggtgac
     2881 cacggtcctg acctacggcc agccggaact cgtgctcttg gaggagtccg cgaacgccgc
     2941 gctggtggtc gtcggcaccc acccccactc cgccctcacc gagaccgtgt tcggctcgcg
     3001 cgccggcggc ctcgtcagag acgcggcctg cccggtcgtg gccgtgccgc ccgactcggc
     3061 ggcgtcggac cggacggggc cggtggtggt cggcgtggac ggcagccccg cctcccaggc
     3121 cgcgctgggc ttcgcgttcg acgcggcgtc gcgccgcggt gtcccgctcc gcgtggcgca
     3181 ctactggtac ggcgagctga ccgacgtcga gagggtcgag gccaggcagg accaccacat
     3241 cctcctggcc gagtcgctcg ccgggtaccg ggagcgccac cccgacgtgt cggtcagttt
     3301 cgaggcgcgg gccgctgacc ccgtcgaggc gcttcgcgct gagtcggcga gcgcctgcct
     3361 gctcgtgctc ggcacgcacg ggctcggccg gctggccagc gtgctgctcg gctccgtgag
     3421 ccgggacctg gtccggtccg cccggtgccc cgtggctgtg gtccgaccgc agggtgagaa
     3481 ggcggagcgt ccttcccgcc tcgcgaacaa cgccgcaccg cgcaccgact gaccactgtg
     3541 gacaaccacg aagatggtgc gacggaacac ctgtcccgtc gtccgcacca cgtggtgatc
     3601 agcggccaga ccggtgttcc actctccgct tcgcggaacg gatcaggagt tcgcggcgtt
     3661 ggcctgcttg atgaactcca tctgcgccgg agtcgaccca ccatagttct cctcgatctg
     3721 cccggcgttc tcctcgtaca tcctggtaca gcgagtccca caggcccggt tcgccgccgt
     3781 ggaactgctc cagcgacccc atccactccc tggccagctc acggccctcg gcgctggtcg
     3841 ggtcggtccc cgcgccgatc gccgcctgca cgcgaccgat caggtccggc cactgccgct
     3901 cgacctcggc gatggcctgc tcacccagct tctaccaccg gtggcgccgc cggatcaccg
     3961 cagagtgcat cgagccggag ctggccatgc ctggaggcca cgccgctggc cgagctgatc
     4021 tcggccggtt cgccatcccc gcgcgtgcgg tgccgatggc ctggtcgtga accgggccag
     4081 gtcaagcagg gaggcatccc cgcgcgtgcg gggccgatgt ggtgcggagc ctccaggact
     4141 cccggacttc cgaggcatcc ccgcgcgtgc ggggccgatg ccgttctggc gtgcacagtg
     4201 gacgaacaca gagaggcatc cccgcgcgtg cggggccgat gctttctggc ctggcacttt
     4261 gtctcagggg tggctgcttt gcacatgtcc acgtgaaacc gtagtacggg agtggcgggt
     4321 cgaggtcgtg tggcgtggag cgcctgtcgt tcggctgggt acgcctgggc gttcatatcc
     4381 gcacgccgcg accaggcggt tcctgatgag acaccttgga tgttgacaag agaagctttc
     4441 tgttcgttcc tctccacgag atcgtcggtg tggcctcgta ctctcccgtc cgaagtgccg
     4501 cagaggctga ggaggctgtg tgtggttcgg cgatgacccg cagattgtgc ggtggctggg
     4561 cgttctgtgg gggaagtcga gggagaaggc tggtggtgtc accaacctgt tgatgtcgca
     4621 cctgctggac acggcatccg taggggaggt gatctgggat cactaccttg cgccggcaac
     4681 gcgtgacctg ttggacgagg tggcgggcgg gacagggcga ggcaggctgt tgttcgcctg
     4741 gctctgcgga atccacgact gcggcaaggc cacgccggct catcagcgcc tgtggctcga
     4801 gggtgcgcag gccgtgaacc gggccgggct gtcctggaat gagccgatgg tggcacggtt
     4861 tcgctggcgg catgatcggg ccggtggctt ccttctccgg cgtgctcttc gagaggcggg
     4921 atggcatgcg gaccaggtgg cgtgggtgtg gccgctggtc gcgggtcacc acggtctgtt
     4981 tccctccgag ggacagttgc aggagcctcg ccaggccagg ggggaactcg caggccacag
     5041 tgactggcgc cgtgcccagg ccgcggtgat cgaggtcttc actcgtgagc ttggattcgc
     5101 cgacctgacc tccgtgcaac ccgtcctggc accttcgcgc gccacccagc tacatctcag
     5161 tggactcgtg gtgatggccg actggatcgc cagcgacgag gggcacttca agggcgtcga
     5221 tgacctcgcc cgcgtgagta tcgaggcgtc gagggaacga gccagacgag cgtgggctga
     5281 acttggcctg cgcgggggat ggggctctcg gcctgaacct gggccggagg cgttcgagga
     5341 gcgcttcgcg cagtcgccgc gaccgtcgca gagactggtg atcgaggctg ctcggacgat
     5401 ggcggagcct ggcatcatgg tggtcgaggc cccgatgggc gagggcaaga ccaaggctgc
     5461 gttgctcgcg tcggaaagcc tggctgcccg tttcggcgcg gacggggtct tcgtggggat
     5521 gccgacccag gccaccagcg acccgatctt cacacaggtg cgtcagtggc tgggatgcat
     5581 cgatccggaa ctgtccgcac aggtggcgtt gctgcatggc aagcgcatgt tcaacaagga
     5641 gtggcggcgg ctgctggagc cctcccctga tgggacccag gagcggttcg ggggtgtcga
     5701 cgagttcgga atggctgacg aggacgatgc ctacgggttg tcatcgtcag actcccgacg
     5761 gcgggagcgg cagactccgg ccgagtggtt cctgggggcc aaacgaggac tgctgtgtcc
     5821 gttcgtggtc gggaccatcg accagttgct gatggcggca actcgtacca agcacgtgat
     5881 gctgcggatg gccgggctcg cgggcaaggt ggtggtgttg gacgaggtcc acgccgcaga
     5941 cgtctacatg tccaggttcc tcgtcgaagg tctgcggtgg ctggggcagg cccgggttcc
     6001 ggtggtgctg ctgtcggcga ccctgccgcc ccagcagcgc cagcggctga tcgaggcgta
     6061 cctggccggg gcggcctcgc gggaggagtt cgcgctcgac gcgccgattc gggcagcggg
     6121 ctatccctgc gtgaccactg cctggttcga cacgaaccgt cagacgccgg tggtcacaac
     6181 gaacgagacg tcgtcctggc ggcctgacct tcaggtcgag gtggaggtgc tcgccgagcc
     6241 catccccgac cgccgagcca gccgcgagaa gcgacggcag gcccaacacg ccgctgacgt
     6301 cgccgtcgcg gagctgctca gggagcgcct ttcacagggc ggttgcgcgc tcgtcatccg
     6361 caacaccgtg gcccgtgcac agtcgatcta tgagctgttg cgtcaacctg cgtggtttgg
     6421 gaaggacgtc actctgctgc acgctcgact cgctgcccag gaacgggccg accgcaccga
     6481 gcgctgtctg aagttgctcg gtgccaggca cgacaatgag ggtgaggaga acgtccagcg
     6541 gccgcggcgg ttcgtcctgg tggccaccca gctcgccgag cagtccttcg acgtggatgc
     6601 cgacctgctg gtcacggatc tgacgaccat cgacttgttg ttgcagcgga tcggcaggtt
     6661 gcaccgacac gagaaggtgg ttcgaccggc aggtgtggac cgaccgcgcg tggtggtcac
     6721 gggattcgat cctggcgtgg gagaagcgcc ggacatcctc ggcgcgagcc agatgatcta
     6781 cgggcgctac ctgatgatgc gttcggccgc cgcggttctc caggtcgctg agctgacaac
     6841 cgacgacgat gcgaaacccg gcaacatctg ggcggtcccg agccaggtgc cggagttggt
     6901 ggcgcgcgtc tatgagccga cctgcgaaat ggtgccagcg gaatggcggg aggccgagcg
     6961 ggtcgcgcgg gaggagtggg agcaacgcca gcgcgcacgt gccgagcagg cggacatgta
     7021 cctgctgacc cggttgggag agcacgagga gcgcaccctg gctgggcttc acttcgctgg
     7081 gccgtccagc gtggggacgg agagggccat ggaagctgtg gttcgcgacg gtgaacccag
     7141 cgtcgaagtg attctggtgg tgcgcgacgg agagcgctac cgcacactgg ctggacgacc
     7201 gctgacgcac aacggagacg tcgctcccga cctgcttgat gaggtacttg gcgcgacagt
     7261 gcgactgccc tcgaagttca ccgacctcgc cctcgaacag ttgaggcctc tggctgggtg
     7321 gtacggacat ccctggcttc ggcacagcct cgcgctggtg ttggaccagg ctggccgtgc
     7381 cgaggtcgac gggcggccct tctgcctgcc caacggcaca accctgcgct acgacaagga
     7441 gcttggactg gtggaggagg cgagcacggc cggccggtag gaggcggcct cggaaggtga
     7501 acgggatgtg ccaccctccg aagccatccc cgcgtgtgcg gggccaacct ggaacccttg
     7561 atccggcaca tacacagcca cggctcaccc ccgcgggctg gtgaccacct cagtggcgcg
     7621 gggcgcccca aagatacccc catccttgac tcagagctac aagctgatac tctctgcact
     7681 cacatacaaa gccagtttcg tcccgagggg catatggtca acttagtgga cgacccgtgg
     7741 ctgctcgcct atccctgcga gggaacagag gtgaaggagc agtcgctacg gggtctccta
     7801 cttgacgcgc accagttccg cgatcttgtc gtggacttcc ccacgcagaa gcccgcgctg
     7861 ttccgacagg tcctgctgcc ggtcgtcctc cacgcgctcg gacgtccacg tgacacgacc
     7921 gcctgggtgt cactcttcca gcagcgagag ttcacgcagg accaacgtga ccggttggac
     7981 cgatatctcg acgagcaccg tcacctcttc gagcttttcg atgacgtcaa ccccttcgcc
     8041 caggtcgcga acctggaggc cgtcagcggt gagacgaaag ggacggcgtc gctggtggtg
     8101 acagcgccga cgggcaacaa cgtccccctg ttctcgtccc ggtctgatgc cgaccctctg
     8161 gagttgactc ccgcgcaggc ggcacgatgg ttgatccacg cgcactgctg ggacaccgcc
     8221 gcgatcaaga ccggggcggt gggggacccg aaggtgaagg ccggcaagac caccggaaac
     8281 cctgtcggcc cgttgggtca gctcggtttc gtcatgccgg tcggcagcac cctctacgac
     8341 acgctactgc tgaacctgcc cagcggcccg gcggcgcggt ccaacgaccg tcctcagtgg
     8401 acgcggcgga acatgaacgg caaggtggag gagacccact cggttgctct ccccgcctgg
     8461 cagccccggg cggccgaggg actgctggac ctgtggacgt ggcagtcacg gcggattcga
     8521 ttgttccctg agtacaccga cgccggtgtg cgcgtgtccc gggtgatcat cgcggcgggc
     8581 gaccggttgt cccaggtgcc ggacttcgag ccgcacacgg cctggacgct ggaggccact
     8641 gggaagacca cgcgggccaa gcagcgaaag ccagtaccac cgcgcagacc tcgacgccat
     8701 caaccgggca aggccgtctg gcgagggctc gatgccctac tggcggtaag ccgagaagac
     8761 cgggaagcgc aaacgaacgc cacgggatac gcgaccagca tcctgctcga ccaactcaag
     8821 gcacggcggg aggagatgcc tctggactac ccgttgcaaa tcgaggtctt cggagttgtc
     8881 tacggcaacc agtccgcgat cgtcgaggac gtgatcacgg actccatccc gctgccactg
     8941 gcggcactga gtgatgactc cttggccagg gccgtcatcc tggaagtcgt ttcgcaagcc
     9001 gaggatctgg cgaacacggt caatcacctc tccgccgacc tacgtcgtgc gctcggtggt
     9061 gagccgatcc cgtgggacaa gggacaacgg cctggcgagg tgctcctgca tgcccttgac
     9121 gacctggttc ggcggctgtt ggccgggctt cgtgccgcag gcgagaaccg cgacctggtc
     9181 gagcgcgggc atctggcatg ggaacagaag gcgttctcgg ctaccgcgca ggtcgccgag
     9241 cgtctgttgg gttctgttcc tggcagcgcg ttcctcggtc atacgatcca gagtgaccgg
     9301 gaacagcgca cctaccgtct cgccaccgcg gaagcgggct tctggcgaca acttgaccgc
     9361 attctctggc gtgccgccgc cgagcggaaa agccgggagc aggacggcga ccagaccacg
     9421 aaagccgagg aagcatgagc gagaagaccc cctcgcgcta ctggacgcgg ttcatcggcg
     9481 ccgacgggaa gtggcgtcgg gcccgggaaa aaaaggacca gatgccgcca ggcgaggatc
     9541 tggcggtgtt gcggacagga ctcgaccgac cagcgggcac ggtgttcgcc ctggtgccgt
     9601 tctacacctc tcccatcgac gaccatgccg cccgcagggg agaggtttcg gtggagcagg
     9661 ccgccgagca cgtggcactg gcgctgttcg gcctgcacca gcaaggccaa cgttcaccga
     9721 tgcacaagcc gggcctgagc gtgggacgag cgctgcggcg gctgcggcag accggcaggt
     9781 tcgctgaaga agctctcgac cggcgggtcg ccgcgacggt gaacgcgacc agcgtctccg
     9841 cgttcgccta tcggttgcgc ggtctggtcg accaactccg gacccagggc atcccgctcg
     9901 actacgacct gctgctacag gacgtcctcg attggcatta cagcgacggg cgccaacgag
     9961 tgcgtcgtcg ctgggggctc gcctacttcg actggagttc cgcgtccacc gctgccgcga
    10021 agcccaccga atcctgagca gtgccttcgc tccccctccg cccttcccag ggcgacgagc
    10081 gaggttgtcg ttccccgatg tctttcgact gattcacttc gtttcggcgg ccatcgccgc
    10141 cacgtcgact acggagatct catggcccag cgccgctacc ttgacgtcca catcctccag
    10201 accgtccccc cggccaacct caaccgagat gaccagggga accccaagga ggcgtacttc
    10261 ggtggggtgc gccgctcccg agtgtcctcg caggcgtgga agagggcgac gcggaagttc
    10321 ttcgccgatc acgagaacgg agtgcccaag gaggacctgg gcgtccgcac caggaggatc
    10381 gtcagcaagc tgggttcgct cgtggccgaa cgcaccacgg ccgtggacgc cgagacggca
    10441 ggcaggttgg ccgctgaagt ggtgtccacg ctggggatca cgccggggaa gaaggacagt
    10501 gagaccgcct acctgctctt ctacgggcgg cgccagctcg tggcgttggc agacctcctc
    10561 gcgtcgcggg ccagcgaact ggccgccctg gaggagtcgg cgctgaaggg agaactcaag
    10621 aagctgccga tcgtggacac gttgggcgcg gggcatcccg tggacgtggc gttgttcggg
    10681 cgaatggtcg ctgacgtgcc cgcgctcaac gtcgacgccg ccacgcaggt ggctcacgcc
    10741 ctgtccaccc acgccaccga gcttgagttc gactacttca ccgctgtgga cgacgagaac
    10801 gacgacgaca aggacgagct cggggccggc atgatcggca cggtcggctt caactcggcc
    10861 actctgtacc gctatgccac cgtggggctg caccagctcg tcgacaatct cggggatgtg
    10921 gccgccgccc gccgcgcggc cggcctgttc gtccagtcgt tcgcccggtc catgcccacc
    10981 ggctacggca acgccttcgc ccatcggact ctgcctcacc tcgtcgcgat cagcgtgcgc
    11041 gcggatcagc cggtgaacct ggtctcggcg ttcgagaacc ccgttcccgc gacccagggc
    11101 atcgcggccg cctcggctcg acgcctggcc cgcgaacagc gcaccgctgt gcggaactgg
    11161 ggtgatgaac ccctccacac gggcctctgc cacagcttcg gggatgacag ggaaaccgcc
    11221 gccgaactcg ccgaggcgtt cggtccggca cgaaccttcc ccgagctgct caccgaactg
    11281 gacagtcacc tcgccgagtt cggggagaac gcctgatggc gacccccagc cccagcgttc
    11341 ccagtgatac cgggcaagcc gtcctgctcc ttcgcctggc ggggccgttg cagtcctggg
    11401 gtgaccgcag cgcgttcaac aggcgcgaca ctcgacccga acccaccaag tcgggaatca
    11461 tcgggctgct cgccgccgct gagggtcgtc cgcggggcga gtcggtggct gacctgaccg
    11521 ctctgcggct cggagtgcgc gttgaccagg ctgggcgact gcttcgcgac taccacaccg
    11581 tcagcgacta ccgagggggc ccgcttcccc aagccggagt ctcggccaag ggcgtgcaga
    11641 aacccacgtc gccgcccaag ttcacccacg tcacgacccg cttctacttg gaggacgcgg
    11701 tgttcgtggc cggtctggcc ggccctcggg atcttctgga gcgccttgac agcgccgtcc
    11761 gccggccggc gtttcccctg gcgctgggac gtcggagctg cgttccgacc cagccggtga
    11821 gcctgggcct gcgggaagga tcactgagga ccgtgctggc caacgaaccc tggcaggtcc
    11881 ccgcccgggc tcagcggcgc ggcccccgca gtgtggacct gcgtgtcgtg ctcgaaggcc
    11941 aggaggcgct cgaaggccag aacgtgcccg acggccagaa cgtggaagag gacctggcct
    12001 acgacgtgcc ggtcaacttc gacccccgcg ccagggcttt cacctcccgc cgcatccagc
    12061 gcacgtggct gtcggttccc acggccgcca ccgccagcgc caccaagaac gatcccgacg
    12121 tcgattctgg ccatgacccc ttcgctctcc tcggctggta agcacatgcc ctacctatcc
    12181 cgaatcagga tcaacccgct gcgtaaggca agtcgccgta tgctggccaa cccccgcgac
    12241 ctacacgccg ccgtggtcaa cgcgattccc gaccatccga ctactgaacg cagcctgtgg
    12301 cgcctggacg ccgacgaccc gcgtcggcca cacctggttg tcctcaccca gtcccggccg
    12361 gattggaacc acctcgtcga gcaggccgga tggccggagg ccgacggcga gcacttcgtg
    12421 atcgccgact acaacccgct gctgagacgt ctgcgggctg gtcaggagtt cgccttccgc
    12481 ctgaccgcca acccggtgca gaacacccgg acgccggaca aacccacgga gcggcaggcg
    12541 caggacgaca ccgtcaccgc acggaggcgt tcatatcgac tcggccatcg aaccgcggcc
    12601 atgcaactga ggtggtttct tacccggacc ctcaagtggg gattcgacgt gcccgaagcc
    12661 ttcacagcgg aaccagccgt cgacatcgat cctcacacca cgcccgaggc tgagacggat
    12721 agcagccttg accaggcccc gcgggacgtg cggatcatcg cccgcgaacg ccgctcgttc
    12781 agcaagcgag acgggaaacc gcccgtggtg ttgtccaccg tcaccttcca gggccggctt
    12841 cgcgtcaccg acccagagct gctcaccgaa cggcttcttg ccgggatcgg accgggaaag
    12901 gcctacggtt gcggactgct caccctcgct ccactgacga agccgtcgac ggggaccggt
    12961 gacgcgcgtg gctgacatct ggtggaaggc cgacccgctc gacctgcacc gcttggttga
    13021 ccgagtctca agcatctacg tggaacggag tcatatcgac cgggacgaga acgccgtcgt
    13081 cctgattaac aagcgtgaga ccgtccgggt gcctgccgcc ctgatcgccg tcatgctgct
    13141 gggccccggc actcgtatca cccacggtgc cgtcaacctg ctcggcgatt ccggcacagc
    13201 cgtgtgctgg gtcggcgagc agggcgtccg gctgtatgcc tcgggattgg gacccagccg
    13261 cggtgccgga ctgctgaatc gccaggcctg gttagtcagc cgccgtcaac atcgtcttgc
    13321 cgtcgcccga gccatgtacg ggatgcgttt cccgggcgag gacgtctccg agatgacgat
    13381 gcggcagctc cgcggcaggg aaggagcccg agtgcgcaag ctctaccagt cgcactcccg
    13441 gcgcaccggt gtcccgtgga acggccgcgt gtaccgcccc ggcgaaccct tcgcggcggg
    13501 cgatgacctg aacaggctgc tgtcggcggc caacgccgcc ctttatggca tttgccatgc
    13561 cgtcatcgtc ggtctgggcg ccagcccagg gctcggcttt gtccacaccg gtgcggccac
    13621 ctcgttcgtc atggacatcg ccgacctgta caaggccgag tacaccattc ccctcgcgtt
    13681 cgacctcgcc gccaaaggac ttgtcacgga gcgagatgcc cgggtcgccc tgcgagaccg
    13741 catcgccgag aaccgccttc tgggcacgat catccgggac gtgaaggcgc tgctgactcc
    13801 tgaaggggcc gagggcgagg acctcgacca ggacctcaac gagttgtggg acgaggaggt
    13861 cgggtcggtc cctggcggag tcaactggtc cagcgagccg atagacgata tcgccatgtc
    13921 gctggtcgat cccgggatgg gggaacggca catagcggtg gtcggtccgg agttcgacac
    13981 tcccagtgac gggttgaggc ggccaggacc agcgtcatcg tgctcatcgc cgcacccgag
    14041 ggactacgtg ggcacctgac caggtggatg gtggaggtca acgccggagt gttcgtgggg
    14101 aacccgagcc ggcgcgtccg cgatcggctc tgggacctgc tggccagtcg gatcggtgag
    14161 ggacaggcgg tgctcgtgga gccttccgac aatgagcaag ggtgggccgt tcgcaccgcg
    14221 ggccgagacc gttggtatcc agtcgacttc gacggactgg tactttcggc acgtctccgc
    14281 cgatgaagcc gcaggtcaac aagtgtcgtc cccgcccgcg cggggatagc tccacctgca
    14341 cgttgacggt ggaccaggac atcgcgtcgt ccccgcccgc gcggggatag ctcgaacttc
    14401 gattcggagt cgtccttctt gccgcggtcg tccccgcccg cgcggggata gctcgtatca
    14461 catcgacgag gcggtggagg ctctgtagtc gtccccgccc gcgcggggat agctcccact
    14521 tcagatgagg actgtgatgg cccccaaggt cgtccccgcc cgcgcgggga tagctcgcgt
    14581 gcggtgcgag ggcgttcaca gacggctgcg tcgtccccgc ccgcgcgggg atagctccct
    14641 ctacgaccgc cgccggggcc gggtcgccac gtcgtccccg cccgcgcggg gatagctcct
    14701 ggtggttgac tgcacccgcc gatcgggggt agtcgtcccc gcccgcgcgg ggatagctcc
    14761 cgccgtcgcc gctatccctg gctgcccggc ctgtcgtccc cgcccgcgcg gggatagctc
    14821 gccgagagac cgggcgcacc ggctcaggac ggggtcgtcc ccgcccgcgc ggggatagct
    14881 ccctgctgcc gctcgccagc cgccaggtcg gccagtcgtc cccgcccgcg cggggatagc
    14941 tcctcgaccc gcaccacgaa gcggtcttcg atcaggtcgt ccccgcccgc gcggggatag
    15001 ctcctcggcg atggtgcggc gcggccgcag gcctttcggc ctgcgcggtg accggtggcc
    15061 cggcgattgt gggaggcggt gccgccgctc tcggcggcct cgccatggcc atcgacggca
    15121 tcaagggcgc cgccgaaggc atcaagaaga acagcaacag gccgtcgaac gtggagccgc
    15181 cccacgaagg ttcgcggaac tatgacgtgt acgatcccgc caacaaggga agaagaatca
    15241 cggacattga catcattgag aatagaattc tctgggagag gaagtctgct gcttgggtac
    15301 aaatccccga agattgggtg cggcaacagg tcgtcaaaaa gctgaactcc tacattgagg
    15361 cacagaagta catgcctggg tgcgaaaggc gccgatcgga atccgattcg agaaggcggg
    15421 cgtcgaaacc gcgccgcgga aagaaattga gaacggcgtc gacgcggtgt gtggaagtaa
    15481 ccctgatgtg aaaatcctct tggagttctg gtaatgggat acgtgttcga agttgagggt
    15541 gagaccgtgt ggagcccgtc gcttgacatt ggtcatctgt ttatggatat cgctaatagg
    15601 ctctctgagg atctgaaaca aagccacggg atgtcgttga tggcgagcga cttcatcgac
    15661 atcgaccgag acgccttcgc tgcgttcgtg cggtccatgc tcaacagctc ggtgatgaca
    15721 aacttgacct actacgtgct gtctcgggga ttccttgcga cctgcctggc gatgttggag
    15781 cgtgcgggct cccctgttgc ccctcagaac tcggaacaac aggatctcgt ggcgttcgga
    15841 aaggctcttc tggggcacat gcccaccaac taggtgtgct cgacctgtaa tcgggtagac
    15901 gcttggtcga gcttctgacg cggaaagccc ttgaacgggc tttccgcgtc aggtgacaaa
    15961 aacgcatctg gtgccggaat cgccctgccg gaactgcctg gagcggcagc cgagggggga
    16021 tggcgtcgag gtgggacagg gagggagaac gcctcggtca ggcaggccgg ttggggcctg
    16081 gcctggtccc gggagtggtc gggaccaggc catggcgagg gcgcctgtca ggggcggggg
    16141 atggagatga cgttgtaggg ggtggtgggg gtgggcgtgg tgttgaagcg ggcgttgggc
    16201 aggtagaggc ggtcgcggaa ggaggcgacg gtggtgggga cgtcgaagcg ggggtcggtg
    16261 acccgcttgg tgagggtggc ggagtgtcca ctgtggtcca ggctgaggac ggccacggtg
    16321 ttcaggcggt tctggacgac gtagagggtg tcaccttcgc ggagcagtcc atcgccgcgg
    16381 ggcagttgct cgccgtggag gtcgacggcc ttggcgacgc cggaggccgg gtcgacgcgg
    16441 aagaggatgc cggtgttcca ctggatcacc aggagggcct tcccgtccgg ggtggtggcg
    16501 atgccgttgg cgttggtgcc ctcccggtac acgatgtcac cgctcaaccg gaggcggacg
    16561 acggccgaag gagcgggcaa ctccccgtcg cgccccaggg ggagctggta gagcaccggc
    16621 tgcgtcgagt cggtcagcca cacggcgtcc ggggtgagga ccacgtcgtt gacgaaactc
    16681 gcgccggtgg cgaggcggta ggtggccagc aggttcccgg tgcggctgtc gatcaccttg
    16741 aggtcgcccc caccgccgcc ggcgacgaag agccggcccc gggagtcgac ctttaggccg
    16801 atggcggggg aaccggaacc ctggcgcagc gtcctcccgg tcccggtcgc caggttggcc
    16861 ttgtagatgg ctccggtccc catggacccg aagtaggcgt acccgtcgga gtcgatcgcg
    16921 atcccctccg gccggaaacc ggcgggcagg gagaacgacg acgggtaggc gccggcctcg
    16981 gccgtgcggt gggcggcgac cggcgcggcg gcggccgcga ccgcgaggac caccgaggcc
    17041 atctccaccc acagactccg tctgcgcatg atcatgtcct tcccgaaccc ggcgacgtgt
    17101 ggtcgccacg agtggtgtcc gttcgttcgg gcggcggacc cggggcacgg ggtcgggcgg
    17161 cgggaagaag agaggtgggc ctcgcgggca ctcacggcgc ccagccaggt catcggcgcg
    17221 cccaccacgg ccagcgaccc tccctcggcc ttgtcgtccg tcgggcgagt tccccgggac
    17281 tccgatgtaa gcgcgcggag gcgggccgtg tcgagccctc ccctgggggt gtgtcaccgg
    17341 gtgagacacg ccaggggagc ggaacacgag tacgacgaac gcgagaggac gaacgtcggc
    17401 gtcgcgatcg ctggcaccgc gggcgccggc gtcacgaacg cgagaggacg aacgtcgggg
    17461 tcgcgatcgc tggcaccggg gtcgtcggcg tcacgaacgc gagaggacgg acgtcggggt
    17521 cacgatcgct ggcaccgcgg acgtcggcat cccaaacgcc agacgacgaa catcagtatc
    17581 acgagcacca gcatcacgag caccggcatc acgaacgccg gcactacgag cgccagtacc
    17641 gcgaacggcg gtacgacggc accaacaaca ccagtaccac ggacgccagt acgaggaaca
    17701 cgagtaccgc gaacgacagt gcgccgaacg gcttggcttc agaacgcgga cagtcgacga
    17761 gccggggctc aggcctcgcg ggcaccggcc cgccgcgctg ggaggggcgg acgacagccg
    17821 tggcttgaat gatcatgtgg agggggtgcg ggagaggtgt cccttgtgga cggcggggcc
    17881 ggggtgcggc cggacggggg ctggggtact ccgggagcat ggcgcggatg cgtggggtgg
    17941 tcgagcgccc tgaggggctc gtccaccagc ccgacctgct cgacgaggcc gaggagcggt
    18001 ccctgctcac ggcggtcgag gcgatgcccc tgcacgaggt gcggatgcat gggcaggtgg
    18061 cccgtcgcac ggttcgtcac ttcgggttcg actacggcta cgagtcgtgg cggctgacgc
    18121 cgaccgatcc cctgcccgag gagttctggt ggctgcgcga ccgctgcgcc cacctggccg
    18181 gcctccggcc ggagtccctg gcgcagacgc tcatcgcccg ctacccgccc ggcgcgacca
    18241 tcggctggca ccgcgacgcg ccgatgttcg gcccgtccgt ggtcggggtg tcgttgttgt
    18301 cgtcgtgcct catgcggttc cagcgccgtg tcggcgagga gcggcgggtg tacgagctgg
    18361 agctggcgcc gcggtcggcc tacgtcctgt ccggcgcggc gaggtccgcg tggcagcaca
    18421 gcattcctcc ggtgcccgag ctgcggtact ccatcacctt ccgcaccttg cgcgaccccg
    18481 cccggtgagg cggggcgccg gccgagggcg cgccggagtg agaccgtcgc cccggcgccc
    18541 ccgcgtcggc gggcggccga gatggcgcga cccgaggctc ctcctggtaa caaagaaaga
    18601 aatgcgtgag cttcctcgcg gcgtgttccg gcggctcggt ggggaaagtg gctgctttct
    18661 ttcagtggcc gaattttcgt gtccacggcg tgaattgtga tcatgggttc ccgtcgacgc
    18721 cgtccggagt agcgggcggc cggtgtcgcg cgcggcggcg ggtgcgcggg gcgcgacggc
    18781 cgttgccctg gacggacgcg gggcggctac tcccgcccct tcgaggtcgg ggacgcgccc
    18841 gtcgcggcgg ggacgtgtgg ctttcacgga agcgaacgcc cggtcgagtg tggtggtgat
    18901 acgggcgtcc gcacaggtcg gtcaaggcgg gggaacggtg aatatcgccc ctccgtccgg
    18961 tgaacgccgg ggtggccgga tgccgcctag ttcgcgcggc gtagccctgt cgccgatcac
    19021 tcggacggct ctgtcccctc gatctcggcc gccggtagcg tcgtcgccgt tcggaaatgc
    19081 accggaaacc cggatgtttg gcgacacgac cctgcccctc gttccgtcgc catccgtcct
    19141 ttgctggcac gccaggactt gggggtcgtc gcgtgaaggc actgtcgttc gaagctccgg
    19201 gagaagcggt tttcggcacc cgcgaggtgc ccgttcccgc gccgggagag gcgctgatcc
    19261 acctcgggta caactcgatc tgcggcagcg acctgtcgct gtaccggggc gtctggcacg
    19321 gcttcagtta ccccgtcgtg cccggtcacg agtggagcgg caccgtcgtc gaggtcaacg
    19381 gacccggcgc cgagctggtc ggccgcgacg tggtcggcga cctcacctgc gcgtgcggct
    19441 cctgcgcggc gtgcgggcgg gggacaccgg tgctctgcga gaacctccag gagctggggt
    19501 tcacccgcga cggggcgtgc gccgagtaca tgacgatccc gaccggcaac ctccacgtgt
    19561 tgccggaggg cctgtcgctg cgggcggcct gccaggtgga gccggtcgcc gtcgccctgc
    19621 acgcggtgtc cactgtgggc gtcgagcccg gtgagcgcgt ggccgtcctc ggcgcgggcg
    19681 ggatcggcct gatgctgatg caggtggccc ggcagcgcgg cggcgtgatc accacggtcg
    19741 gcgagccggt cgcggagcgc agggcggtcg ccgcccagct tggcgcgcgg acggtgacca
    19801 ccggccgccc tggcgagctg gcggagctgg tggctaagca ccccgacctc acgccggacg
    19861 tcgtgctgga ggcctccggc tacccggtcg cggtccagga ggcgatcgag gtcgtgcgcc
    19921 ctggcggccg gatcgggctc gtggggtacc gggtcgagga ggtcggcccg atggcgaccc
    19981 accacgtcgc cgtgaaggcg ttgacgatca ggggttcgtt ggggccgggc ggtcggttcc
    20041 ccgaggccat cgacctgctc gcgcggggag agatcgaggt cgagccgctg ctcagccacg
    20101 agttcgcgct ggacgaccac gccagggcgc tggacctcgc gctgcgtcgc gccgagggca
    20161 acgtccgctc gttcttcaac ctccgcgcct gaacacgccc gtccgacggc tcctgtcggc
    20221 gcctgtcagt gtccgtgagc gcctcactgt gcccgacggc gcgtgtcagg gctggcggcg
    20281 aagcgtcccc gcgtcgacga cgacgctcca cccgcgcccg cagcgccggg cgacctccca
    20341 gggagcgatc cgtgtcccac ccagccgcgt ccaccgaccc gcccacaccc gcgggtgagc
    20401 cgtccacaga ggacagctcg tccgacgggg cctccgcgcg gggcacgggt tcccggagga
    20461 cgacgcggcg cctgtgcctg ttcttcgggc tgcacgagct ggtgccgttc ttcccgctct
    20521 acccgttgct gttcgccgac cacgggctgt ccaccgccgg catctcgggt ctgctggcct
    20581 tctggtcggt cacggccttc gtgctggagg tgccctccgg cgtcctgggc gacatgttct
    20641 cccgccgccg gctgctcgcc ctcggcgtcg ccgtgcgcgc ctgcgggttc ggcctgtggg
    20701 tcgccttccc gtcgccgtgg gccttcgcgg cggggttcct gtgctggggc ctgtgcgacg
    20761 cgttgacctc ggggacgctg gagtcgctgg tctacgatga gctgcgcgcg gcgggcgcga
    20821 ccgggcggta cgcggcggtc atggggagcg ggcgggccgt gtcgctgctg tcgacgctca
    20881 ccgcgatcac gctggccggg ccgctgttcg cgctcggcgg ctacccggcc gttggggtgg
    20941 tcagcctcgg cagcgggctg gcctgcgccc tcgcggccct gtcgttctcc gagccgccga
    21001 gggagcaggt ggacagcgag ggcggagggt ggcgctggta cgtggccacg ttccgcgccg
    21061 gggtgtccga ggtgcgcggg gaccgggtcg tgctgcgcgc ggtgctggtc gccgcgtcgc
    21121 tgcacagcat gacggcgatc gacgagtact tcccgatgct ggccagggcc aacggcgcgt
    21181 cgacgacgat ggtgccggtg ctggtggcgg tgaccgtcgt ctgcgccgcc gtgggcagcg
    21241 gcctggtcgg caggaccgcg cacgcgccgt ccggcgcgct ggggctggcc ctgttggcct
    21301 cggcggccct gctggccgct ggagcgttga gcgggctcca gtccggcatg ctggccgtgg
    21361 gcgtgagctt cggcctggtg cagtgggcgc tcgtgctggc cgacacccgg ctccaggacg
    21421 cgatcaccgg gccggccagg gcgaccgtga cctccgtggt cgggttcggc tccgaggtgg
    21481 cctcggtcgg cttctacctg gccgccggcg cggtctccac cgtcacctcc atgtccacgc
    21541 tggtcgcctg gttcgcggtg ccgctggtcc tcatcgcggt ggtcgcgttc cggtggctgc
    21601 gccgggagcc gtgtcccacc ggccaggtcc gccccgagcc ggaaccgcgg cggcgcgact
    21661 gaccccaccg gcgccggagc ccggctcggc ccaccgccga cggacaccgt ccccccgcac
    21721 tggttcaccc acacccgcgc ccgccgcccg gcggccatcc cgcacccgtg tccgttcccc
    21781 gacccacgag gagcacgtcc catgacccgg accaacgaga ccatcgcgac gatcacggac
    21841 tggagccgct ccgccgagca cctgcgccgg tcgcacgagg tcaccacgaa cccccgtccg
    21901 gacgaggacg gccagtaccc ctgcgtgctg accaggggtt ctggggcgcg cgtgcacgac
    21961 atggacggca acgcctacct cgacctcacc tgctcgttcg gcaccgtcct catcggacac
    22021 gccgagcgcg aggtcaccga cgcgatcagg gcgtgcctgg acgaggggaa cctgttctac
    22081 accggcccga gcccccggcg gctcgccctg gccgagcgcc tcctcgactg gttcccctgg
    22141 gccgaccagg cgttgttcta ccggaccggg tcctgcgcgg tctcgtccgt cgcccggctc
    22201 tcccagcacg tgaccggcag gaccgccgtg ctcacctccg gctaccacgg ctggcacgac
    22261 tggcacctgg aggcggtgcc ggaggccaag ctcttcccgt cctatgccac ggagttccac
    22321 gacgacctcg acgtctaccg cgcgtacctg gaccggcacg cggacgagat cgcggccgtc
    22381 gtcgtcaccc cggagccgac ccggcacccg ctggagcact accggacgct gcgcgacctg
    22441 gcggccgagg ccggctgtct gttcgtgctg gacgaggtca agaccggcat gcgggcgggg
    22501 aagggcgggc tcagcgcccg cgccgggctg gagcccgacg ccgtgaccgt ctccaaggga
    22561 ctggccaacg ggcacagcat ctccgccgtc gtcggcagcc gccggatcac cgagggcctc
    22621 gccgaggccc acgtgtggtc cacctaccag aacgagcagg tgggctacgc cgctgcgttg
    22681 tccactgtgg acttcttgtt gcgggaggac gtggccggcg tcgtggagcg cacggggcgg
    22741 acggtcgagc gggccttccg gagcgccttc gcggagcggg gtctcccggt ggaggtgcac
    22801 ggctgggggc cgatgttcga cctcgacttc tccgccgcgg aggaggacct gccggagcgc
    22861 ctgcaactcg ccctgctgcg gcacggcgtc ttctgcgacg tcggcgacga cttcaacctc
    22921 atgtaccgga tggccgacca cctcgacgag ctgctggagc gggtcaccgc cgcgatcgcg
    22981 tccgtgtgag acgccgggcg gggccggacc cgaggggaag gggaagcgga tgctgctgat
    23041 ctcagcggac gaggccgcgc gtcggaccta cgacgcctgt gtggtcggca gcggcgcctc
    23101 gggatccgtg gccgcggccg tgctcgccga acgggggctg tccgtgctcg tcgtggagca
    23161 gggcggcccg atcccgcccg gcgcggacgt ggaggaccac gaggaccccg acgggtgggc
    23221 gttcgcgcgt cgccacgggc ggtggacgcg cgacggcttc ccgtggaccg ccatggcgct
    23281 cggcggcggc accgtgttct acgccgggat gtcctaccgc taccaggact ccgacctggc
    23341 cccgccctcg tcgctgctcg gcgaggccga ctacgaccac tggcaggtcg gcctcgccga
    23401 cctggagccg cactacgagt ggatcgagta ccagctcgcg gtggccgggc cgtcccggaa
    23461 gcgggtgggg gactacgtgt tccccgtcta ccaccggccc agcctgccgc ccaccccgcc
    23521 cgggttggcg ctcgccgagg gcgcccgcgc cctcaacctg acgcccctgc ccacccccgt
    23581 ggcgatcagc gggatccggg accggttcgg ccccgggtgc gcgcaggcca cgccctgcac
    23641 gtcgttctcc tgccccaccg gggcgaaggc cgacgtcgtc agccgggtcc tcgccccggc
    23701 cgagggcgac gtctcggtgc tcgtccacac ccgggtcgac cgccttgtgg cctccggctc
    23761 ccatcgggtc gacgccgccg aggtggtcga ccgggggacc ggcacgcgcc ggaccctgcg
    23821 ggcgcgccgg ttcctggtgg ccgccaacgc catccagtcc gccgcgttgc tgctccggtc
    23881 gaccagtcgg ctcgaacccg acggcctggg caacggcaat ggcctcgtcg gccgccacct
    23941 ggcgatgaag aacagcgtct acgtgcgggg agtcgtgccg cgcaggcttc ccgggtacac
    24001 accgctgcgg caccggtact ccagcgtctg cgtgttggac tacctgaccg gagaggagtt
    24061 ccccgacggc gtcggcggcc tgatccacga ggccaacccg tgggagccgg cggccgagcg
    24121 cgaggccgag cgcggcaccg tgctccaggt cgagtgtctg ctgggcgacc ggccccaggc
    24181 gcggaaccgg gtgcggctgt cccgcacgcg cgaccgcgac ggctttcccc gcatcgtcct
    24241 cgactacgag ccccaccccg cagacctcac gcggttggcc gtgttgtccg agcgcgccac
    24301 cgacatcctc accaaggcag gggcgatcga cgtgcgggag gtggacaccg cctacgagct
    24361 gggcagcgcc cacctgcacg gcacgctgcg ctccggccgc gatccccgca cctcggtgac
    24421 cgacccgttc ggccgcctgc acggctacga caacgtgtgg gccgtggacg gcgcgacctt
    24481 cccgttcgcc ggcaacccca accccaccct gaccatccag gccaacgccc accggatcgc
    24541 gtccgcgatc gactgacggg ccgggcgtcg gccccgccac accggttcct cacaccggtt
    24601 cctcaccccg gttcttcaca ccagctcccc gcgccggctt ccctcaccgg cttccccatc
    24661 ggaggtagag acatgcgtgt cctcgggctg aacggctggc cccgcgactt ccacgacgcg
    24721 tcggcggccc tgctcgtcga cggccggatc gcggccttcg ccgaggagga gcggttcaca
    24781 cggaagaagc acgggtacaa cacggccccg gtgcaggcgg cggcgttctg cctcgcccag
    24841 gccggcctga ccgtggacga cctcgacgcg gtcgcgttcg gctgggacct gccggcgatg
    24901 taccgcgagc gactgggcgg ctggccgcac tccgacagcg aggcgctgga catcctgttg
    24961 cccagggacg tgttcccccg gcgcaccgat ccaccgctgc acttcgtcca gcaccacctg
    25021 gcccacgcgg cgagcgccta ctacttctcc ggcgaggacc gtggcgcggt gctcatcgtg
    25081 gacggccagg gcgaggagga gtgcgtgacc ctcgcccacg ccgagggcgg caagatcacc
    25141 gtgctcgaca cggtccccgg cgcgtggtcc ctggggttct tctacgagca cgtgagcgag
    25201 tacacggggc tcggcgggga caatcccggc aagctcatgg gactggccgc gcacgggacc
    25261 acagtggacg agacgctgtc cgccttcgcg ttcgactcgg acggctaccg cctgaacctg
    25321 atcgacccgc aggcccgtga ccccgaggac tgggacgagt actcggtgac cgagcgggcg
    25381 tggttcgccc acctggagcg gatctaccgg ctgccgccga acgagttcgt ccgccgctac
    25441 gacccggcca aggggcgggt cgtccgggac acccgacggg acccctacga gtaccgcgac
    25501 ctcgcggcca cggcgcaggc cgcgctggag cgggcggtgt tcggcctggc cgactcggtg
    25561 ctggcccgca ccggggaacg caccctgttc gtcgctgggg gcgtgggcct caacgcgacc
    25621 atgaacggca agctgctcac ccggtccact gtggacaaga tgttcgtccc gccggtggcc
    25681 agcgacatcg gggtcagcct cggcgcggcc gccgcggtcg ccgtcgagct gggcgaccgg
    25741 atcgcgccca tgggcgacac cgcggcgtgg gggccggagt tctcccccga ccaggtgcgg
    25801 gccgcgctcg accgcaccgg cctggcctac cgggagccgg cgaacctgga gcgcgaggtg
    25861 gccgccctga tcgcctccgg caaggtggtg ggctgggccc aggggcgggg cgaggtcggc
    25921 ccccgcgcgc tggggcagcg cagcctgctc ggctccgcgc actcgccgac catgcgcgac
    25981 cacatcaacc tgcgggtcaa ggacagggag tggtggcgcc cgttcgcccc gagcatgctg
    26041 cggtcggtca gcgaccaggt actggaggtc gacgccgact tcccgtacat gatcatgacg
    26101 acgaaggtgc gcgccgccta cgccgaacgc ctgccgtcgg tggtgcacga ggactggtcc
    26161 acccggccgc agaccgtgac cgaggcgagc aacccgcgct accaccggat gctcaccgaa
    26221 ctcggcgacc tcgtcggcga ccccgtctgc ctcaacacct cgttcaacga caggggcgag
    26281 ccgatcgtgt cctccccggc cgacgccctg ctcaccttct cccgcctgcc gatcgacgcc
    26341 ctggcggtcg gtccgtacct ggtcacgaag gacctccgcc actaggccac cacgcgtcaa
    26401 tcccgttgac tcccaacagg atcgccagtt tcacgaggcc ccgaccctca ccaggctcac
    26461 cacgtccacg ggactcacct ccctcgtcag tcctcagtgg acacatcacg gccggcgaca
    26521 gagtcgccgg cgccggcgac gtcaccgaag tgcccctccg gtcgaccacg cggccgcccc
    26581 cgtcacgccc gcagaggaag ggttcgtcga ccatgcccgt ccacctcgcg atcaacaacg
    26641 gaacacccgt gcgcacccgg ccgtggccgg tctggcccca gcccgccagg ggcgcgctcg
    26701 acgcgctgga gcgcgtgctg cgctcgggcc gctgggcgat cagcggcccc taccggggca
    26761 tcgagtcggc cgagcgccgc ttcgccaggg acttcgccgc ctacaacggg gtcgcgcact
    26821 gcgtccccgc cgccagcggc acggccagcc tcatgctcgc gctggagtcc tgcggcgtgg
    26881 gcgtcggcga cgaggtcatc gcccccggcc tgtcctgggt ggcctcggcc tccaccatcg
    26941 tcggcgtcaa cgccgtcccc gtcctggtcg acatcgaccc gaggaccctg tgcctggacc
    27001 cggccgcggt cgaggccgcc atcacccccg ccacgaaggc cgtcgtcgtc gtgcacctgt
    27061 actccgccgt ggccgacctc gacgcgctgc gcgcggtcgc cgaccggcac gggctgccgc
    27121 tgatcgagga ctgcgcacag gcccacgggg ccgagcaccg gggtcgcaag gtcggctccg
    27181 tcggcgacgt cggcacgttc agcatgcagc acagcaaggt gctcaccagc ggcgagggcg
    27241 gggccgcgat caccaactcc gccgagctgg cccgcaggat ggagcacctg cgcgccgacg
    27301 gccgctgcta ccccgacacc gcccccgcgc cgggccgcat ggaactggtg gagaccgggg
    27361 agctgatggg cagcaaccgc tgcctgtcgg agttccaggc cgccgtcctc gtcgaacagc
    27421 tcagggaact ggacgagcag aacgccctgc gccgccgcaa cgccgaactg ctcaacaccc
    27481 tcctcgccga gcaggggctg cgcccgcagg ccacctcgcc gggcaccacg tcccgcacct
    27541 actacgtcta cgcggcggag ctgcccgacg acgcgttcgt cggcctcccg atcaccacgg
    27601 tgaccgaggc gctcaccgcc gaactcggtt tccccatctc gccggcgtac gcgccgctgc
    27661 acaccaaccg gctctacgcg ccggcctccc gccgtcggtt cgcgctcggc gaggagcacg
    27721 agaagcggat cgaccccgcc cggttccacc tgccggtgtg cgagcggctc acccggcgcc
    27781 tgatcacctt ccaccacgcc gcgttgctgg gcgacgagtc cgacatgcac gacatcgccg
    27841 ccgccgtcgc caaggtgctg cggcaccacg gggagctgcg ggcctgagcg cccgctccgg
    27901 accttgggga gcgcagatgc agaccaccac catcaccatg ggagacgtcc agtacccgta
    27961 ccggctgggc accggctgcg tcgacgggat cgtcacccgg ctcggcgagc tggaggccag
    28021 ccactacctc gtgctgtgcg acgcgaccgt cgccgagctg tacggccacg acctcgccgc
    28081 gcggctgcgc cgctcggccg gtcccgccag cgtcctgacg cacccggccg gcgaggagca
    28141 caagggcctc ggcacgctgg acacgctcgc cgacgccgcc ctccacgcgg gcgtcgaccg
    28201 gcgcggcgtg gtcgtcgccc tgggcggcgg cgtcaccggc aacatcgcgg gcctgctcgc
    28261 cgccctgctg ttccgcggca tccgcctggt ccacgtgccg acgaccgtcg tggccatgct
    28321 cgactcggtg ctgtcgctga agcaggccgt caacgcgcag gtgggcaaga acctcgtcgg
    28381 caccttctac ccgccggtgg aggtgctggc cgacaccgcc atgctgggca ccctcccggt
    28441 cagggagatc cgctcgggcc tgtgcgaggt cgtgaagaac gcgctggcca tccggcccag
    28501 catgatcgac ttcctggcgg ccgagctgag accggacggg cggtacgccg acgacgtcct
    28561 gcgctggatg atcgacgaga gcgtcgcggc caaggcccag gtcaccgagc acgacaagta
    28621 cgagcggcgc gagggcctgg tcctggagta cggccacacc gtcggccacg cgctggagca
    28681 cgcctcgcac ggcgcggtgt cccacggcgc aggggtcggc gtgggcatgg tcgccgcggc
    28741 cgaggtcgcc cgccggctcg ggcacgtcga cgccgacctc gtcgagctgc acagggagct
    28801 ggtcggcaag gtcggcgtcg cgacgacgct gccggccgac gtgccgaccg aggagatcac
    28861 ctaccggctc ggcttcgaca acaagcgggg ctaccagccg ctgcccgccg accactacgc
    28921 catggtcctg ctcgccgacg tcggccaacc cctgtaccag gacgggctgc cgctcacgcc
    28981 ggcgccccgc gccctcgtgg acgaggtcgt ccgggagctg gccgacgccc cgtcccggat
    29041 cggggcgtcc gtgggttccg ccggaggtgc gtcgtgaact ctccgctcaa ccagccaccg
    29101 cacaagtcac tgaacgagcc actgggcaag tcactgaacg agccactggg caagtcactg
    29161 aacgagccgc tgggcaagtc actgaacgag ccgctgggca agtcactgaa cgagccgctg
    29221 ggcgtcgccg tggtcggcgc ggggttcatg ggaggcgtcc acgccgaggt gttcgccgag
    29281 cacccgaggg cgcggctcgc cgcggtctgc gacctcgacc ggggcgcggc gcgcgagctg
    29341 gcggggcggt tcgccgtcga gaccgtcacc gacgacctcg acagcgtcct gtccgacgac
    29401 cggatcgggc tggtcgtggt gacgacgccg aacgccctgc acgccgagca ggccgcacgg
    29461 gcgttgcggg ccggccggca cgtgctggtc gagaagcccc tcgcgctcac ctccgacgag
    29521 atccgcggcc tgctccgact ggccgacgag cgcggactgg tgctcgcgca cggcagcaac
    29581 ttcgtgcaca gccccaagtt ccggcgggtc cgcgagctgg tcgccgacgc cgacgcgttc
    29641 ggccggccgc acctggcgcg ggtcgtcgtg cgcaacgggg gaccggactc cgggtggtgc
    29701 ctggacccgg cgctcgccgg cggcggcgtc ctgctcgacc tcggctgcca cgcggtcgag
    29761 atctgccggt ggctgctggg cggcgcggag gtccgcgccg tcaccgcgcg cagccagcgg
    29821 gtgcggcccc gcgccgggcg ggtcgaggac caggcgacgc tgctgctgga gttcgccgac
    29881 ggcgcgctgg gccagtgcga cgtctcctgg gcctgtcccg gcggtgagga gatcacgacc
    29941 gaggtgctgg gcaccagcgg tcgggccggc gccgacctgt gggccgggat gggcgtgcac
    30001 gccttctccg aacggggctt cgccagcgtg tgggagccga accaggggtg ggtccgcccg
    30061 gagtgggagt gggtcagggc gagcggctac acccaccagg accacgccgt ggtcgaggcg
    30121 gtcctggacg gcacacccct gccgcactcc gccgtcgagg cgtggacctc ggccagggtg
    30181 ctggaggcgg cggcggagag cgcggccacc ggccgcaccg tcgagctggc cccgtccccg
    30241 aacggccacc ctgtgcccga cgccgtccgg ggaggcgacc gtgtccactg aggacagtga
    30301 cagaccggtg cggcggcggg gcggcgtgct ggcgctcacc ccgttcttcc tctaccccga
    30361 gtaccaggac tgctggtcgg cccggttcga ctcgatgggc gggatgcacc tgctggtgcg
    30421 ggcgctcgtg gaggagatgg ccggcagggg cgtcccgcac cgcgtgctca ccatggcccc
    30481 gcccggcgtg cccagggacc tggccatcgc ccgcaacgtc accgtccacg cgcgacgcct
    30541 cccggtgttg ccgatcccgt cccagttgga ggggtacttc gggctggtcg gggcgtgggc
    30601 caaggggagc ctgctgtggg tcctgcggaa ccggaggcgg ctgcggcggg agatctccct
    30661 ggtgcacgcc cactgcgacg ggtcgggctc ggcgccgttc tacggctggc tcatcgcgcg
    30721 ggcgctgggc gtgccgctgg tggcgcagat ccactccagc cggttcctga gccagcaccc
    30781 cacgacgttg tgggaacggg tcaccgaccc ggccgcgaag tgggcggagc ggttcaccgt
    30841 ccgcaacgcg gcggcggtgc tgatgctcac cgagaaggcc cgcaccgaga tgcgggacgc
    30901 ggcggcgctg gacccccggc gcgtccaccg gctggcctac ctggccagcg accgcttcgc
    30961 cgagggcgac accgaggagc ggaggaccga gatcaggcgg cgcttcggcc tggacaccgg
    31021 ccagcccgtc gtcctctacg tcgggcggat cgcggccgag aagggcgtgg agttcttcgt
    31081 cgaggccgcc gccgaactgc ggcggcgcgg gcgtaactgc cggttcctcg tcgcggggga
    31141 cggcccgacc cgccaggaga tcgagaagct ggccgaggac aggggcgtcg ccgaccggat
    31201 cacgatcacc ggtttcctgc cgcacgagct gatcccctcg gtgatggcat tgtcccagct
    31261 cgtggtcctg ccctcccggt acgaggaact gggcatcgtg atcctggagt gcatgagcat
    31321 gcgccggccg atcgtcgcgc acgacgtcaa cggcgtgcac aagctcatcg agcatggcag
    31381 gaccgggctg ttggtgccgc cgttcgacac gcccgcgatg gccgacgcca tcgaggcgct
    31441 gctggacgac ccggagctgc gggagcggat cgccgagacc gccgccccgc tgccgtccgc
    31501 gaagtactcg ctgaccacgg cggcggacca gctcacggac atctaccggg agctgggcgt
    31561 atgcgtctga ccctcctcgc cccgcacccc gacgacatcg cgttgtccgt cgggggatgg
    31621 ctggccggtg tcggcccgcg cctgcgtgcg tccgggtggc gactggacct ggtcacggtg
    31681 ttcagtcgca gcgtctacgc gcccttcgcc ggggacgacg cgcgggacga ggacgccgtg
    31741 agcctgctcc ggctggccga ggacctgcgc ttcgcccggt cccagcggct gcggccctcc
    31801 gcgctcgggc tgcccgactg ctcgtgcctg ggcatggacg acgagtcgga actggtggcc
    31861 cccacggcca ccgacccacg caagtccatt gtggacgatg ttgtcgctcg ggcggtcgcg
    31921 gggagcgccg tcgtcgtcgc gccgttggcg gtgggcggcc acgtcgacca ccggctggcg
    31981 cgcgacgccg tcgccgaagc gctcggggag atcccgtgcc tgtggtacga ggacctgccc
    32041 tacgcgctcg acgacgccgt gcccactccg cgctccccgg tcgacgggcg gacgctgcgc
    32101 ccctggccgg tgcggatcac ggcccagctc cctgccaaac gcgccgcgct ggcctgctac
    32161 cggtcccaga tgagcgacac cgacatcggg gaggtcctca actaccgccc cgacggcggc
    32221 gccgagcccg tcgaacgcct gtggacctcg gccgacctgc ccccggacct cgcagggacc
    32281 ctcggcctgg tcgaccagga caccccctca ccccacctca tcccggtcaa cctggaggac
    32341 aagtgacctc ggaactcgcg ttgttcggcg gcacacccgt gcgcaccgag cccttccccg
    32401 acggcccccg cttccgcgag cgggacctgg agcgcatccg ggaggtgctg gagtccggca
    32461 gcctcggcgg catccccttc ccgaaccgca cccaccgggc gttcgccgag cagttctgcg
    32521 gccggctcgg cgcccggcac ggcgtgctgg tcgccaacgg caccgtgagc ctgtccgtgg
    32581 ccctgcgggc cctcggcgtg cacgccggtg acgaggtgat caccaccggc tacacgtgga
    32641 tgggcacggc cgcgtccatc gtgcacatca acgccgtgcc ggtgctcgtg gacatcgacc
    32701 cgaacacctg gtgcatcgac ccggcggccg tcgaggcggc catcacgccc aggaccaggg
    32761 cgatcgtgcc ggtgcacctg gccaaccaga tcgccgacct cgacgcgctg ctggagatcg
    32821 ccaggaagca tgacctggtc gtgctggagg actgcgccca cgcgcacttc gccgagtggc
    32881 gcggccgctg cgtcggcacg cacggcgacg ccggcagctt cagcttcgag agcagcaaga
    32941 tcatgacctc cggcgagggc ggattcctgg tcagcgggga cgagaccacc caccaccggg
    33001 ccatgtcgct ggtcaactgc gggcgcaagg aggagggcta cgactccttc gagggccgca
    33061 tgctcggctg gaacaaccgg gccaccgagt tgcaggccgc cttcctcatc ggacaggtcg
    33121 aacagcacga cgagctgcac gcccagcgga agtccaacgt ggagctgctg accaaggggc
    33181 tcaccgagat cggcggcttc acgccggtcg gcgacgacga ccccagggtg acgcgccggc
    33241 agtactacga ggtgctctac cgcttcgacc ccgagcagtg ggcgggcgtg caccgcgacc
    33301 gggtgctgga ggccctgctc gccgagggcg tcgagttcga gggcatcacc ttctacccgc
    33361 cgctgcaccg ggactcgctg ttcacggtca gcgccgagga ctggccgatg atccgcgacc
    33421 ggtacggcga ccgcatgggg ccggaggact tccacctccc ggtctccgag cgggccgcct
    33481 acgacgagtc ggtgtgggtc caccactccc tgctcaccgg cccggccacg gacgtcgacc
    33541 agatcctgga ggccgtggcg aaggtccgcc gcaacgtcga cgccctgcgc tgacccgaca
    33601 gcgccgttgg gtcgctttcc cgaccgcacg atccgaccgg acggaggcgc cgtgaacccg
    33661 acgaggcagg accttcggac cgatcccccg cgccacggcg acggcctcca cgacgcggtg
    33721 gacctgttgc gcagggccat ggcgctggtg ctcgcccaca ccgaccagtg ggacgcgctc
    33781 ggcgcggcga gcgtcgcggc cgtcgaggcc gcgctggaga tggtcgcggc caacgccggg
    33841 acggccacgg ggaacggcgc ggcgcccgcg cccgccggac cccgaggccg gcggaccgag
    33901 gacatccagc gggccgtcga cagcgccagg gccgcggtcg tcgcgagcac gttcgccctt
    33961 cgcgaggcgg ccgatgagga acgccgccgg cggcagacgc ctccgccgcg cgcgggagcc
    34021 tgaccggggc ccgcgcggga gcctgaccgg ggcgcccgcg cgggcgtctg acaccacacc
    34081 gcgcccggcg cggccgacca gccgcgcgcc gcggaacggc cactgcccgc acccccggcc
    34141 ctcccgccct ttccccgcaa ccctttcccc tcttcctgtg gcttctcccc gacactcctt
    34201 cctcggacgg cgccgacgcg gcgcgctggg cgccagatgg gacgtggacc cgtgcgtgtt
    34261 ctccggctca ccccgttctt ccaccacgac tgcgtcacct cgtggccggc cgagttcgac
    34321 gcggtcggcg ggatgcagtt gcagatcctg cggctgtccc gcgagctggc ccggcgcggc
    34381 gtgcgccagc aggtgctcac gctgggcttc cccggcctgc cccgggtgcg ggtcgactcg
    34441 ccgaacctgg tcgtgcggat caccagggcc ccgctgcccc ggctgcggtc ggagctgacc
    34501 ggcctggtcg ggctcaacca ggcgtggctg gtcgccgcgc tggccgcgtg cgtgcggctc
    34561 aggcgcacct ggcgccccga cctggtccac gtgcacgccg acggccagct ctgggcgttg
    34621 ctggcgggac cggccgcgtc ccgcgtgctc ggcgtgccct actgcgtgac gctgcactgc
    34681 tcgcgcctgt cggtgtacca gcccatgtcg tggatcgacc agctccagca ccggctggtc
    34741 gtcgcggcgg agaagtgggc gctgcgcggg gcctccggcg tgtcgaccct gaccgaccgc
    34801 accgcgtcgg tggtcgcctc cgcgctcggg gtgggcgcgg aggacgtcga cgtggtcccc
    34861 gactcggtgg acacgtcgtc cactgtggac agagcagagg ggcgcgtgct gctggagaag
    34921 ctgggcgtgc cgtccgacca cgaggccgtc ggctacgtcg gccgcgtcgc gcacgagaag
    34981 ggctggcccg acctcgtgcg cgtggccggc gcgctgtccg accggaaggc gaccttcctg
    35041 gtcgtcgggg acgggccgca gagcgggcgc atgcgcgacg aggtcgccgc cgccggcctg
    35101 tccgaccggt tcctgttcac cgggttcctg ccccatcacg acatcccggc ggtcatggcc
    35161 ggtctggacg tgctcgtgat gccgtcgcgg cacgaggagc tgggcgggag cgcgctggag
    35221 gcgatgctgg cgggaacgcc cgtggccgcc tacgccgtgg gtgggctgcg ggacaccgtg
    35281 ggccacgtga cgccgtcgct gctcgtgcct cccggcgacg tcacggcgct cgcggaggcc
    35341 gttcgtggtg tgctcgacga cccgcggccc caccgcgacc aggtggcggc cggccgttcc
    35401 tggctgaccg acctcttcga cggcggtgcc gccgcgcgtc gggtgatcgc ccactatgag
    35461 cgtgtcctca gtggaaccgc ccgtctccgc cctcaggaat aggacggtgt gtttcgtact
    35521 ccgatctcac cgacgtttcc tgtgggttcg cggtctccta ctgcgccgac accgcccctc
    35581 attcgagacg gagtgcgctt ctgtccggat gtcagtccgg ctccagactc gtcgcgctcg
    35641 ccgcgtggcg gaccacacgc gccttggtga tcgcccatgt cgtgcacatc ggcatctctg
    35701 tcgcgctcgt gactgggtcg ggaggctgga acgccatcgc agtgaacgga cacagtcgac
    35761 gagtagggga agaatccgtc gccccggtca tccgtgagtc ctcccgggcg gctgtcggca
    35821 caacgaggcg gcgttcggtg gggcgcggtg tgcgtcgggt ggtcgcgcac cacgagcgtg
    35881 tcctcagtgg aaccgggcgg ccgcgcttga gtccctgatg acgccgctga ccgcgtcaac
    35941 cagtccacct cgacaccgga accgtccact ccgaacggtc cgagtggcgc aatgcccaga
    36001 cccgggccac tgccccagac ggatcaccgg cgtggcgcac gggcgcattt agccggccaa
    36061 tcgtcaccaa ggacgtggtg accccgcccc gcagcaccta ccttgcaccc tgagcggacg
    36121 ccctccggct gccctgggcg gacgagaagt ggatgggaag tgccgtggag acgggcgctg
    36181 gcggacgatt gggcgtgttg ttcgccggtc tgttccggat cgtcaccgac acggccgacc
    36241 actgccggaa ccggttgttg aacctcttcc gcggccatca cgttccggcg ggtcgcgctg
    36301 tgccacgccc gtcttggcct taacagcacc ctggtgatca cgcaggcctc acctgtgggc
    36361 gttccttcgc gccggaggcg ggcggtagtg gtcggctacg aggtcaagcc cgcgcgaccc
    36421 ggcaggggga gaaggtatgc cggcctgtgt ttcgttgctg acgaaacaca ggccgtggtc
    36481 cagcaactcg tctatgcggg gccggtggcc ccaccgggac cgctggcccc gtccggacgt
    36541 caggacctct gatgccttct ggctgtccgc tcaggagatg tcggcgcgga ccagggcggc
    36601 ggcctgctcg gccgacccct ccgccgcctc cgccgaatcg cccaccgtga tcaccgcgcc
    36661 caggatgcac gacttgaagt ccacgggtgg ctgggtgatc tcggcgccca cgggttgctc
    36721 gatcaccagg tggcgcacgc cgggcacgcg gcaggcgtcg tcgagaccgg cgtagccggt
    36781 gagggttccg acccggtcgg tcaggatctt gcgcacacac gcccacaggg gcggcccggc
    36841 ggcgtccagc gggggacgac cggtcgcgac ccggatcgcg ttctcgacga acgaccggcc
    36901 ggtggccagc ccgaccaggt gcgaggcgat gaagtccccg ccaccccttg ccccgatctc
    36961 cacgagtctc accccgccgt ccggggcaac catgcattcc aggtggaagg cgcagtcgtc
    37021 cagccccaac gcggacacca cgtcggccgt gagccggtgg acggcgtcga gccggtcggc
    37081 gggcagcgcg ctcgggtgca ggtgcgcgag ttccagccgg aagggctcgg tcgtgcgctt
    37141 gtcgatgacg ccgacgacgt ggatctgtcc acaatggacg aatccctcga cactgtgctc
    37201 cgtgccgtgc aggaactcct cgtagatcag ctcgtggcgg gtctccgtgg tcgccgtcag
    37261 gtccatcagc cggtcgaacg cgggacgcag gccagcaggg ccgtcgatca cgaagatgcc
    37321 ccggctgcct gacgaggacg tgggcttgag cacggcgggg aaaccgacca gctccaccgc
    37381 gcgcgacagg tccgaccagt cggtgacccg cgcgaaccgg gggaccaggt gcgggtggtg
    37441 ttcggccacc gcctcccgca tcaggtactt gttgcgggcc agccgggccg cgccggggga
    37501 gacgcccggc agcccgagcc gctgggcgat cccgctgacc gtggtcacgt cgcgctccga
    37561 ccagcccagc acggcggcga tccggtgttc cgccgcgatc tcgtcgaccg ccgcgtgcac
    37621 cgccgcctcg tcccgggtgt ccagtcgcac cacggtccgc acgatcccgc gaggtaaacc
    37681 ctccggcacc gcgtcggcga gcagtgcgac gccgtagccg aggcggtgcg cggcctcgaa
    37741 caccgcaccc cgctccagat gcgtgcgacg gacgttgacg aagacgacga gttcgttgtt
    37801 caccaaggtt ctccgaggga aaggcgaggg tgtgggcggg ccgtgcgccg acccgccaca
    37861 ccctcctgga ttcagctcgc cgaccgcgtc ggcaggagtt ccggggccgt ggccgcgacc
    37921 gccgccgtgt tccgacgcgc caccgcgacc tgggcgatga cgatgccagc caacatcacc
    37981 accgagccca ccatctgcac cgcgccgagc cgctcgccga gcaccagcat ggccagcacg
    38041 ccgccgacca cgatctccag cgtcgcgacc aggctcgccg acgtgggcgg gatcgaccgc
    38101 tgcgccgtga cgctgagcag gatcgcgccc gccatgccga ccagccccac ccagagcgcg
    38161 agcagccaca ccggcacgtc caccccgccg accgcgctga cctccccgag gacgtggaac
    38221 gggaacgggg ccaccacccc ggcgagggtg agcgcgaccg cgccgaggca ggtgccccag
    38281 gtcgccatca ccaacgggtc gtagtcccgc agcccccgtt ccgccaggag gaaccgcccg
    38341 gcgagggtgg ccgcggccag caggccgaac agcacgccca cgccgtccag ggcgaacgac
    38401 gtccacacct gactgatcaa cgccaggccg cacaacgcca ccgcgatccc cacccacagc
    38461 aggccggaga ggtgcttgcg ctgcacgaac cgcacccaca gcgccacgag caccggcgac
    38521 aggtactcca gcagcagggc gatcccgacc gggatccggg acagggcgac ggtgtagacg
    38581 acctggttga ccgccagcgt caccaccccg tacagcacca ccagccacca gtcacccggc
    38641 cggatccgca accgcccccg ccgcagcagc agggccgccg tcaacagggc cagcgcgccg
    38701 acgaccgtgc gcacctggat gacgttcacc ggggacagct cggtcctggc gagcagcttc
    38761 aacgcggggg ccgagctgcc catcgccacg gcccccgcgg ccccgagagc caggccgagg
    38821 gccaggctcc cgggccggga acgggacacc atcaccggac ccgccgcgcc accacgtcgg
    38881 ccagcgcccg cgcgccgcgc cggaacgcct ccagtgacaa cgcctggaac ggcaaccgga
    38941 ggaacagcga cccggcgggc aggcgctcgt cggggaagaa cgccgatccc cgggagagcc
    39001 gcaccccggc ccgctccgcc gcggccagga actcggcctc ggtcaggtcc gaccgcacca
    39061 gggcgctgac gaagtacccg ccgccgggct cggacagcag cccgtcgccg aacgcctccc
    39121 gcgccgcctc gaccgccgcg tcgtgccgag gggccaggaa ggtcacggcc cgctggatcg
    39181 accgctccac caggccgtcc tccaacgcgc gcgccgccac cgcctgcgcc agcggcgacg
    39241 cggtgaggta ggtgccctcg gcgagttccg cgagctggac catggtgtcg gcgtcgccga
    39301 tcgcgtagcc cacccgcagg ccggggctca gcaccttgct caacgagctg atcgtgagca
    39361 cccggtccgg ggccagctcg gccagcgtgg gcgccgccgc gccccggtac cgcagccgcc
    39421 ggtacggcgt gtcctccacg atcaggaacc cgtactgccg ggccagaccc accagcgccc
    39481 ggcgcttctc ctcgctcatg cacacgccgg ccgggttctg gaagtccggg atggtgtaga
    39541 agaacgcggg cgtgtgccgc gccaccaggt cccgcaactg gtccaggtcc gcgccgtcgc
    39601 cccgcaacgc cacgccggtg acctgcccgc cgtgccgctc gaagatctgc cgggcccggt
    39661 cgtaggtcgg ggcctcggtc agcacggacc ggccgaaccg gccgatcagg tggcgggcca
    39721 gcaggtccag cacctggagc gacccgttac tgacgaagat ccggtcgggg tcgacgccgt
    39781 ggtgccggcc gagttcggcg cgcaaccgct cgtcgccccg gttccggccg atcggcgcgt
    39841 actggaagac cgcgaccggc gactcctcca gcacctgggt ggtcagcttg gccaactcgt
    39901 cgaccaacag cacctcggcg ggcgggacgc ccctggtgaa cgggaccagc tcactcgtgt
    39961 gatctgccat ggatgcgtga ccgccatttc cgtcgtgaga gtcctctgtg gactcatgag
    40021 gactcgtggg gactcgtggg gactcgttgg gggactcgtc gggactcgtc aggcgagact
    40081 catcggaggg actcgtcggg gaggaaaccg ggcgcgcggg ccacgaactg cccgcccagc
    40141 tcggaaaccg aggacacgcc gagctggcgc agcgcgtccc tgacctcgac gtcgaacacg
    40201 tcgagcacct gctcgacgcc cttctggccg ttcaacccga ggccccagag gtacggccgg
    40261 ccgacgcaca ccgcgtgcgc gcccagcgct agcgccttga ccacgtccac accggaccgg
    40321 acaccgccgt ccaccagcag ggtccgcccc ctgggcagga cccgggcgat ccggtccaac
    40381 gccaccagac tgggcagtgc cccgtcgagc tggcgtccgc cgtggttgga cacgatcacg
    40441 ccctcggcgc ccagctccac gcagcgcagc gcgtcctccg gccgcagcac gcccttgacc
    40501 agcaccggga gcgtggtcag cgaccggatc cacgccaggt cgtcccaggt caccggcagc
    40561 cggtcgaggc ggccgctcgc cggcgcggcc ccgtcgagga cgcccagggc gcgcagggtg
    40621 ccgtagtcca cgtcgtccgg gagccggaac cccgcgcggc gggtgctgat ccggcgcgcg
    40681 ctgtacgacg cgtcgaccgt gaccaccagc gccgtggccc cgccccgctc ggccagctcg
    40741 acggtggccg ccacgtcctc acgggagcgg tacccgtaga gctggaacca gctcaggccg
    40801 ggcgcctccg ccgcgatctc cgggaacgcg tggtgcgtgt ccgtgctgac gatcgagagc
    40861 acgtccctgg cgcgggcggc gcgggcggtg gccagctccg cgtcggggtg caccaggcgc
    40921 tggggactcg tgggcgcgag caccaccggc gacgacacgg tgcggccgag caaagtcacg
    40981 gacgtgtccg gctcgcccgt cgacgtgcgc accccgcgcg ggagcaacca gatcctgtcg
    41041 taggcggcgg cgttgtcgtc gatggtgcgg tgcgttcccg ccccacccgc gacgtactcc
    41101 cagatggccc ggtcggtccg ctcgcgccag ctccgctcga agtccgggat ggtcaccagc
    41161 tcgtccactc cgacctcccc ggcgctcacc acaggcctcg gatggtcgcc atcgacggga
    41221 cgacccggcc gccgcccatc atgtgctgga ccgtcctggg gatcgcccgc accgagtaga
    41281 accgccgcag ccaccggtcc tggccgtcgt agcggggggt gaacccggaa cgcccgtgcg
    41341 cggcgacgtt gttgtccacg atgacgcagt cgcccggctc caggaccacg tcgtggcaga
    41401 cctcctccag cgcctgggtg aggcggacca gggcggcgcg ccccgccggc gtggtggaga
    41461 aggtgttgtg cgagttgaac cgcaggaacg gccggtcctc gtcgccgaag atcaccgggt
    41521 gcgggccgac cggcggcagc tcgccgcccg cggcgcgggt gaacgaggtg gggtagttgc
    41581 tgaggaacca caggccccgc aacgtggcca cggtgtcgtc gtcgagcagc gcgagcgcgt
    41641 gacggaccga ggcgaccctg gtcgcggcga ccccgaggtg gtcctggcgc aggcagagca
    41701 ggccgaggta gtccgggcgc agcgggtggt ggacgttctc ggtgtggaag tcgaaggcca
    41761 ccgacccgga gttctcgatc cgcgtctcgt cgcccggcac cggctgcacc tcgtgcacca
    41821 gccgcccgtc cttctcgtcg gcgtagccga ccatcgtgcc cagcgtctcc gcgacgagct
    41881 ggagcgtcgc cgaggtgggg tgcgcgtcga gcgtcgtggg ccggccgtcg gtgtgggtcg
    41941 gcgggatctc gccgatctcc agcccgcgca gcaacaggaa cccgtcgacg ccggcgtccg
    42001 cggcgaaacc gcggatcgcg gcgtccagcc cgcccaggtc gggtcgggcg gactccgggg
    42061 ccgcgccttc ctggccccgt ccacccgcaa cccgctccga gtgctcccac aaccggattc
    42121 tctcgtcctc agggacgtgg tacaggggaa tcgtgagcgc cgaggacatc tgatttcctc
    42181 cactgtcggt cctaccgtgc ggcgcgaacg tatcggcggt cgattcccgt cggctttcgt
    42241 cgcgatttcg acggcgcggg tccctgttcc gtcgacatcg aaaaagcgcg tccccgcgtt
    42301 acccggtggt ttctctcccg tcgacgcaca cgataaccgc tccccaggtg gcggcgattg
    42361 aaaattcgcc cgccgtcgcg caacatggtt gcgtgcctcg tgacgggaag gtcctcgacg
    42421 acgtcgacca ccggttgctc gccctgttgc aggaggactc cgggcgcacg ctcggcgccc
    42481 tcggcgagct ggtggggttg tcggcgagcg cggtccaacg ccgggtggag cggtaccgcg
    42541 ccagcgggat cctcgcccgg tacgtggccg tgctggagcc ccggcgcggc ctcgacgtcc
    42601 tgctggcgat ctgcctggtg acgctggagc gcgagtccgg ccacgcccac gaggagttcc
    42661 ggcgccggct gctggcggcg cccgaggtgc agcagctcta caacgtgtcc ggggactccg
    42721 actatgtcgt cgtcctcgcc accaccggga tggcgcacca ccgggaggtc gccgaccggt
    42781 tgctgaagga cgcgccgaac gtccggcgct actccaccct gttcgtgctc gacccggtcc
    42841 ggaccggctc ggcgttgccg acgcggcgtg agggggagga ctgatccggc gggtcagccg
    42901 gccgcgcgag cgtgtggccg acacccgcgc gagacctgac ggacggtctt cccgctggtg
    42961 agggcgggct tgctgggctt gtggcccttc tgcgggtcgc cccgcgccgc gtcccggacc
    43021 gcggcgcggg ggtcgtgtcc cgcctggtcg tcagttcctg atcgtcatcc gtggcccggc
    43081 cgcgtccccg cgcgcccaat tcgcgtcaac aacggtcgtc ggtccggagg cgtcggtgcc
    43141 gcccggtggc gggaaaactg tcgtgaacat tgcaggcggc ggcggacacg cattaccggc
    43201 gcgtcccggc tccgttgatc
//
