BGC0000721: tobramycin biosynthetic gene cluster from Streptoalloteichus tenebrarius
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Location: 1 - 43,220 nt. (total: 43,220 nt).
This entry is originally from NCBI GenBank AJ810851.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000721
Short description tobramycin biosynthetic gene cluster from Streptoalloteichus tenebrarius
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Saccharide
Loci NCBI GenBank: AJ810851.1
Compounds
  • tobramycin
Species Streptoalloteichus tenebrarius [taxonomy]
References
Chemical products information
tobramycin
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C18H37N5O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAH18532.1
 2 - 559 (+) putative acyl-CoA synthetase
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  • CAH18533.1
 1192 - 2202 (-) putative integral membrane protein
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  • CAH18534.1
 2624 - 3532 (+) hypothetical protein
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  • CAH18535.1
 3599 - 3871 (-) putative transcription regulator
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  • CAH18536.1
 4520 - 7480 (+) putative helicase
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  • CAH18537.1
 7714 - 9438 (+) hypothetical protein
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  • CAH18538.1
 9435 - 10037 (+) hypothetical protein
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  • CAH18539.1
 10162 - 11316 (+) hypothetical protein
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  • CAH18540.1
 11316 - 12161 (+) hypothetical protein
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  • CAH18541.1
 12166 - 12975 (+) putative transcription regulator
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  • CAH18542.1
 12959 - 14059 (+) hypothetical protein
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  • CAH18543.1
 14020 - 14286 (+) hypothetical protein
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  • pseudo14971_15142
 14972 - 15142 (-)
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  • CAH18545.1
 15048 - 15491 (+) putative transposase
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  • CAH18546.1
 15514 - 15873 (+) hypothetical protein
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  • CAH18547.1
 16128 - 17213 (-) hypothetical protein
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  • CAH18548.1
  • tobY
 17331 - 17828 (+) putative GTPase, TobY
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  • CAH18549.1
  • tobX
 17829 - 18488 (+) TobX protein
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  • CAH18550.1
  • tobE
 19173 - 20192 (+) putative cyclitol 1-dehydrogenase, TobE
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  • CAH18551.1
  • tobT
 20352 - 21662 (+) putative transport protein, TobT
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  • CAH18552.1
  • tobB
 21802 - 22989 (+) putative aminoglycoside 6'-aminotransferase, TobB
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  • CAH18553.1
  • tobQ
 23030 - 24556 (+) putative aminoglycoside 6'-dehydrogenase, TobQ
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  • CAH18554.1
  • tobZ
 24673 - 26385 (+) putative 6''-carbamoyltransferase, TobZ
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  • CAH18555.1
  • tobS1
 26613 - 27887 (+) putative 2-deoxy-scyllo-inosose aminotransferase, TobS1
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  • CAH18556.1
  • tobC
 27917 - 29077 (+) putative 2-deoxy-scyllo-inosose synthase, TobC
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  • CAH18557.1
  • tobD2
 29248 - 30291 (+) putative hexose-3''-dehydrogenase, TobD2
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  • CAH18558.1
  • tobM2
 30308 - 31570 (+) putative 6-glucosyltransferase, TobM2
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  • CAH18559.1
  • tobN
 31561 - 32346 (+) putative amidase, TobN
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  • CAH18560.1
  • tobS2
 32343 - 33593 (+) putative L-glutamine:hexose-3''-aminotransferase, TobS2
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  • CAH18561.1
 33652 - 34023 (+) putative retrotransposon protein
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  • CAH18562.1
  • tobM1
 34252 - 35502 (+) putative aminoglycoside 4-glucosaminyltransferase, TobM1
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  • CAH18563.1
  • tobL
 36571 - 37803 (-) putative carbamoyl-phosphate synthase, TobL
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  • CAH18564.1
  • tobU
 37872 - 38852 (-) putative transport protein, TobU
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  • CAH18565.1
  • tobA
 38852 - 39970 (-) putative aspartate aminotransferase, TobA
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  • CAH18566.1
  • tobD3
 40080 - 41156 (-) putative L-lactate dehydrogenase, TobD3
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  • CAH18567.1
  • tobO
 41186 - 42169 (-) putative oxygenase, TobO
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  • CAH18568.1
  • tobR
 42393 - 42884 (+) putative transcriptional regulator, TobR
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated reference publication(s) (MIBiG Annotathon)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Removed annotation for duplicate of pseudogene
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