BGC0000721: tobramycin biosynthetic gene cluster from Streptoalloteichus tenebrarius
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Location: 1 - 43,220 nt. (total: 43,220 nt).
This entry is originally from NCBI GenBank AJ810851.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000721
Short description tobramycin biosynthetic gene cluster from Streptoalloteichus tenebrarius
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (None)
Loci
AJ810851.1
via
Compounds
  • tobramycin
Species Streptoalloteichus tenebrarius [taxonomy]
References
Chemical products information
tobramycin Evidence:
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C18H37N5O9
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAH18532.1
 2 - 559 (+) putative acyl-CoA synthetase
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    • CAH18533.1
    		 1192 - 2202 (-) putative integral membrane protein
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      • CAH18534.1
      		 2624 - 3532 (+) hypothetical protein
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        • CAH18535.1
        		 3599 - 3871 (-) putative transcription regulator
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          • CAH18536.1
          		 4520 - 7480 (+) putative helicase
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            • CAH18537.1
            		 7714 - 9438 (+) hypothetical protein
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              • CAH18538.1
              		 9435 - 10037 (+) hypothetical protein
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                • CAH18539.1
                		 10162 - 11316 (+) hypothetical protein
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                  • CAH18540.1
                  		 11316 - 12161 (+) hypothetical protein
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                    • CAH18541.1
                    		 12166 - 12975 (+) putative transcription regulator
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                      • CAH18542.1
                      		 12959 - 14059 (+) hypothetical protein
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                        • CAH18543.1
                        		 14020 - 14286 (+) hypothetical protein
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                          • pseudo14971_15142
                          		 14972 - 15142 (-)
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                            • CAH18545.1
                            		 15048 - 15491 (+) putative transposase
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                              • CAH18546.1
                              		 15514 - 15873 (+) hypothetical protein
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                                • CAH18547.1
                                		 16128 - 17213 (-) hypothetical protein
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                                  • CAH18548.1
                                  • tobY
                                  		 17331 - 17828 (+) putative GTPase, TobY
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                                    • CAH18549.1
                                    • tobX
                                    		 17829 - 18488 (+) TobX protein
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                                      • CAH18550.1
                                      • tobE
                                      		 19173 - 20192 (+) putative cyclitol 1-dehydrogenase, TobE
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                                        • CAH18551.1
                                        • tobT
                                        		 20352 - 21662 (+) putative transport protein, TobT
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                                          • CAH18552.1
                                          • tobB
                                          		 21802 - 22989 (+) putative aminoglycoside 6'-aminotransferase, TobB
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                                            • CAH18553.1
                                            • tobQ
                                            		 23030 - 24556 (+) putative aminoglycoside 6'-dehydrogenase, TobQ
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                                              • CAH18554.1
                                              • tobZ
                                              		 24673 - 26385 (+) putative 6''-carbamoyltransferase, TobZ
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                                                • CAH18555.1
                                                • tobS1
                                                		 26613 - 27887 (+) putative 2-deoxy-scyllo-inosose aminotransferase, TobS1
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                                                  • CAH18556.1
                                                  • tobC
                                                  		 27917 - 29077 (+) putative 2-deoxy-scyllo-inosose synthase, TobC
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                                                    • CAH18557.1
                                                    • tobD2
                                                    		 29248 - 30291 (+) putative hexose-3''-dehydrogenase, TobD2
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                                                      • CAH18558.1
                                                      • tobM2
                                                      		 30308 - 31570 (+) putative 6-glucosyltransferase, TobM2
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                                                        • CAH18559.1
                                                        • tobN
                                                        		 31561 - 32346 (+) putative amidase, TobN
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                                                          • CAH18560.1
                                                          • tobS2
                                                          		 32343 - 33593 (+) putative L-glutamine:hexose-3''-aminotransferase, TobS2
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                                                            • CAH18561.1
                                                            		 33652 - 34023 (+) putative retrotransposon protein
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                                                              • CAH18562.1
                                                              • tobM1
                                                              		 34252 - 35502 (+) putative aminoglycoside 4-glucosaminyltransferase, TobM1
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                                                                • CAH18563.1
                                                                • tobL
                                                                		 36571 - 37803 (-) putative carbamoyl-phosphate synthase, TobL
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                                                                  • CAH18564.1
                                                                  • tobU
                                                                  		 37872 - 38852 (-) putative transport protein, TobU
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                                                                    • CAH18565.1
                                                                    • tobA
                                                                    		 38852 - 39970 (-) putative aspartate aminotransferase, TobA
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                                                                      • CAH18566.1
                                                                      • tobD3
                                                                      		 40080 - 41156 (-) putative L-lactate dehydrogenase, TobD3
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                                                                        • CAH18567.1
                                                                        • tobO
                                                                        		 41186 - 42169 (-) putative oxygenase, TobO
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                                                                          • CAH18568.1
                                                                          • tobR
                                                                          		 42393 - 42884 (+) putative transcriptional regulator, TobR
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                                                                            Biosynthesis information
                                                                            Annotation changelog

                                                                            Entry version: 3

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2022-09-15
                                                                            Removed annotation for duplicate of pseudogene
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 2

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2019-10-16
                                                                            Migrated from v1.4
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            2019-10-16
                                                                            Updated reference publication(s) (MIBiG Annotathon)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                            Entry version: 1

                                                                            Date
                                                                            Changes
                                                                            Submitters
                                                                            Reviewers
                                                                            2015-06-12
                                                                            Submitted
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                            • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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