BGC0000722: validamycin A biosynthetic gene cluster from Streptomyces hygroscopicus subsp. jinggangensis
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Location: 1 - 45,164 nt. (total: 45,164 nt).
This entry is originally from NCBI GenBank DQ164098.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000722
Short description validamycin A biosynthetic gene cluster from Streptomyces hygroscopicus subsp. jinggangensis
Status Minimal annotation: no
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: complete
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other (Cyclitol)
  • Saccharide
Loci NCBI GenBank: DQ164098.1
Compounds
  • validamycin A
Species Streptomyces hygroscopicus subsp. jinggangensis [taxonomy]
References
Chemical products information
validamycin A
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C20H35N1O13
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABA41524.1
 1395 - 2597 (-) integrase
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  • ABA41525.1
 2975 - 4150 (+) transposase
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  • ABA41500.1
 5054 - 5884 (-) transposase
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  • ABA41501.1
  • valO
 6051 - 6716 (-) phosphatase/phosphohexomutase
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  • ABA41502.1
  • valN
 7480 - 8475 (-) dehydrogenase
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  • ABA41503.1
  • valM
 8478 - 9752 (-) aminotransferase
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  • ABA41504.1
  • valL
 9776 - 11254 (-) trehalose-6-phosphate synthase
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  • ABA41505.1
  • valK
 11344 - 12318 (-) dTDP-4-dehydrorhamnose reductase
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  • ABA41506.1
  • valA
 13630 - 14874 (+) 2-epi-5-epi-valiolone synthase
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  • ABA41507.1
  • valB
 14879 - 16000 (+) glucose-1-phosphate adenylyltransferase
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  • ABA41526.1
  • valC
 15997 - 17052 (+) glucokinase
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  • ABA41508.1
  • valD
 17860 - 19215 (+) ValD
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  • ABA41509.1
  • valE
 19643 - 20638 (+) oxidoreductase
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  • ABA41510.1
  • valF
 21457 - 22662 (+) oxidoreductase
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  • ABA41511.1
  • valG
 23045 - 24313 (+) glucosyltransferase
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  • ABA41512.1
  • valH
 24446 - 25642 (+) transport protein
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  • ABA41513.1
  • valI
 26802 - 28637 (+) glycosyl hydrolase
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  • ABA41514.1
  • valJ
 29207 - 30124 (+) oxidoreductase
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  • ABA41515.1
 31746 - 32360 (+) unknown
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  • ABA41516.1
 33340 - 34383 (+) unknown
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  • ABA41517.1
  • valP
 35281 - 36162 (-) regulatory protein
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  • ABA41518.1
  • valQ
 36159 - 36764 (-) regulatory protein
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  • ABA41519.1
 38103 - 38678 (+) tellurium resistance protein
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  • ABA41520.1
 39292 - 40647 (+) unknown
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  • ABA41521.1
 41189 - 42061 (-) unknown
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  • ABA41522.1
 42207 - 43133 (-) esterase
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  • ABA41523.1
 43374 - 44423 (-) cytochrome P450 hydroxylase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: 67IIUGVPORSPZSAXSJ6T72RE, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Corrected compound details
  • Removed incorrect polyketide information
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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