BGC0000723: validamycin A biosynthetic gene cluster from Streptomyces hygroscopicus subsp. limoneus
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Location: 1 - 37,256 nt. (total: 37,256 nt).
This entry is originally from NCBI GenBank DQ223652.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
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KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000723
Short description validamycin A biosynthetic gene cluster from Streptomyces hygroscopicus subsp. limoneus
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Other (Cyclitol)
  • Saccharide
Loci NCBI GenBank: DQ223652.1
Compounds
  • validamycin A
Species Streptomyces hygroscopicus subsp. limoneus [taxonomy]
References
Chemical products information
validamycin A
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C20H35N1O13
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABC67260.1
  • vldT
 1115 - 1555 (+) VldT
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  • ABC67261.1
  • vldU
 2169 - 2942 (-) probable membrane protein
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  • ABC67262.1
  • vldV
 2939 - 3541 (-) VldV
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  • ABC67263.1
  • vldW
 4698 - 5795 (-) putative oxidoreductase
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  • ABC67264.1
  • vldX
 6239 - 7291 (-) putative metalloisomerase
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  • ABC67265.1
  • vldC
 8342 - 9397 (-) putative sugar kinase
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  • ABC67266.1
  • vldB
 9394 - 10515 (-) putative nucleotidyltransferase
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  • ABC67267.1
  • vldA
 10520 - 11758 (-) 2-epi-5-epi-valiolone synthase
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  • ABC67268.1
  • vldD
 13291 - 14175 (+) VldD
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  • ABC67269.1
  • vldE
 14265 - 15758 (+) putative glycosyltransferase
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  • ABC67270.1
  • vldF
 15755 - 17056 (+) putative aminotransferase
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  • ABC67271.1
  • vldG
 17059 - 18054 (+) putative dehydrogenase
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  • ABC67272.1
  • vldH
 18219 - 18860 (+) VldH
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  • ABC67273.1
  • vldI
 19683 - 21518 (-) glucoamylase
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  • ABC67274.1
  • vldJ
 22632 - 23816 (-) putative transport protein
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  • ABC67275.1
  • vldK
 23961 - 25322 (-) putative glycosyltransferase
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  • ABC67276.1
  • vldL
 26926 - 27774 (-) VldL
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  • ABC67277.1
  • vldM
 27790 - 28869 (-) putative oxidoreductase
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  • ABC67278.1
  • vldN
 28893 - 29645 (-) putative dehydrogenase
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  • ABC67279.1
  • vldO
 29648 - 30292 (-) putative O-methyltransferase
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  • ABC67280.1
  • vldP
 30289 - 32124 (-) putative oligopeptidase
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  • ABC67281.1
  • vldR
 35999 - 36970 (-) putative arginase-related hydrolase
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Hidden contributor (ID: SJG3CBEHSM6A3I74YXLH6GLA, no GDPR consent given).
  • Corrected compound details
  • Added extra biosynthetic class and subclass information
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
Similar known gene clusters
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