BGC0000723: validamycin A biosynthetic gene cluster from Streptomyces hygroscopicus subsp. limoneus
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Location: 1 - 37,256 nt. (total: 37,256 nt).
This entry is originally from NCBI GenBank DQ223652.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000723
Short description validamycin A biosynthetic gene cluster from Streptomyces hygroscopicus subsp. limoneus
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (cyclitol)
  • saccharide (None)
Loci
DQ223652.1
via
Compounds
  • validamycin A
Species Streptomyces hygroscopicus subsp. limoneus [taxonomy]
References
Chemical products information
validamycin A Evidence:
Copy SMILES
C20H35N1O13
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ABC67260.1
  • vldT
 1115 - 1555 (+) VldT
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    • ABC67261.1
    • vldU
    		 2169 - 2942 (-) probable membrane protein
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      • ABC67262.1
      • vldV
      		 2939 - 3541 (-) VldV
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        • ABC67263.1
        • vldW
        		 4698 - 5795 (-) putative oxidoreductase
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          • ABC67264.1
          • vldX
          		 6239 - 7291 (-) putative metalloisomerase
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            • ABC67265.1
            • vldC
            		 8342 - 9397 (-) putative sugar kinase
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              • ABC67266.1
              • vldB
              		 9394 - 10515 (-) putative nucleotidyltransferase
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                • ABC67267.1
                • vldA
                		 10520 - 11758 (-) 2-epi-5-epi-valiolone synthase
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                  • ABC67268.1
                  • vldD
                  		 13291 - 14175 (+) VldD
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                    • ABC67269.1
                    • vldE
                    		 14265 - 15758 (+) putative glycosyltransferase
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                      • ABC67270.1
                      • vldF
                      		 15755 - 17056 (+) putative aminotransferase
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                        • ABC67271.1
                        • vldG
                        		 17059 - 18054 (+) putative dehydrogenase
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                          • ABC67272.1
                          • vldH
                          		 18219 - 18860 (+) VldH
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                            • ABC67273.1
                            • vldI
                            		 19683 - 21518 (-) glucoamylase
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                              • ABC67274.1
                              • vldJ
                              		 22632 - 23816 (-) putative transport protein
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                                • ABC67275.1
                                • vldK
                                		 23961 - 25322 (-) putative glycosyltransferase
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                                  • ABC67276.1
                                  • vldL
                                  		 26926 - 27774 (-) VldL
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                                    • ABC67277.1
                                    • vldM
                                    		 27790 - 28869 (-) putative oxidoreductase
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                                      • ABC67278.1
                                      • vldN
                                      		 28893 - 29645 (-) putative dehydrogenase
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                                        • ABC67279.1
                                        • vldO
                                        		 29648 - 30292 (-) putative O-methyltransferase
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                                          • ABC67280.1
                                          • vldP
                                          		 30289 - 32124 (-) putative oligopeptidase
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                                            • ABC67281.1
                                            • vldR
                                            		 35999 - 36970 (-) putative arginase-related hydrolase
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                                              Biosynthesis information
                                              Annotation changelog

                                              Entry version: 4

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-10-07
                                              Update chemical activity to schema version 2.11
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 3

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2022-09-15
                                              Corrected compound details
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              2022-09-15
                                              Added extra biosynthetic class and subclass information
                                              • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 2

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2019-10-16
                                              Migrated from v1.4
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              2019-10-16
                                              Updated compound(s) information (NPAtlas curation)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                              Entry version: 1

                                              Date
                                              Changes
                                              Submitters
                                              Reviewers
                                              2015-06-12
                                              Submitted
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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