BGC0000724: streptomycin biosynthetic gene cluster from Streptomyces griseus subsp. griseus NBRC 13350
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Location: 6,919,728 - 6,951,001 nt. (total: 31,274 nt).
This entry is originally from NCBI GenBank AP009493.1.

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Gene details
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General
Compounds
Genes
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NRPS/PKS domains
General information about the BGC
MIBiG accession BGC0000724
Short description streptomycin biosynthetic gene cluster from Streptomyces griseus subsp. griseus NBRC 13350
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Saccharide
Loci NCBI GenBank: AP009493.1
Compounds
  • streptomycin
Species Streptomyces griseus subsp. griseus NBRC 13350 [taxonomy]
References
Chemical products information
Copy SMILES
streptomycin
Molecular Formula C21H14N7O14
Chemical database entries PubCHEM  
List of genes involved in compound(s) production
Identifiers Position Product Functions Extra
  • SGR_5914
  • BAG22743.1
  • strU
6919728 6921014 - putative NAD(P)-dependent oxidoreductase
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  • SGR_5915
  • BAG22744.1
  • strV
6921491 6923245 + putative ABC-type multidrug transport system ATPase and permease component
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  • SGR_5916
  • BAG22745.1
  • strW
6923242 6924984 + putative ABC-type multidrug transport system ATPase and permease component
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  • SGR_5917
  • BAG22746.1
  • stsG
6925055 6925816 + putative L-glutaminyl-2-N-methyltransferase
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  • SGR_5918
  • BAG22747.1
  • stsF
6925880 6926569 + StsF protein
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  • SGR_5919
  • BAG22748.1
  • stsE
6926566 6927558 + putative ATP:scyllo-inosamine phosphotransferase
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  • SGR_5920
  • BAG22749.1
  • stsD
6927555 6928238 + putative aminosugar-converting enzyme
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  • SGR_5921
  • BAG22750.1
  • stsC
6928245 6929519 - putative L-glutamine:scyllo-inosose aminotransferase
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  • SGR_5922
  • BAG22751.1
  • stsB
6929758 6931281 + putative NADH:N-amidino-scyllo-inosamine oxidoreductase
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  • SGR_5923
  • BAG22752.1
  • stsA
6931338 6932570 + putative L-alanine:N-amidino-3-keto-scyllo-inosamine aminotransferase
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  • SGR_5924
  • BAG22753.1
  • strO
6932612 6933391 - putative glucose-1-phosphate thymidylyltransferase
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  • SGR_5925
  • BAG22754.1
  • strN
6933524 6934447 + putative N-amidionostreptamine 6-phosphotransferase
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  • SGR_5926
  • BAG22755.1
  • strB2
6934444 6935496 + putative scyllo-inosamine-4-phosphate amidinotransferase
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  • SGR_5927
  • BAG22756.1
  • strM
6935539 6936141 + putative dTDP-4-dehydrorhamnose 3,5-epimerase
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  • SGR_5928
  • BAG22757.1
  • strL
6936173 6937087 - putative dTDP-4-dehydrorhamnose reductase
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  • SGR_5929
  • BAG22758.1
  • strE
6937144 6938133 - putative dTDP-glucose 4,6-dehydratase
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  • SGR_5930
  • BAG22759.1
  • strD
6938220 6939287 - putative glucose-1-phosphate thymidylyltransferase
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  • SGR_5931
  • BAG22760.1
  • strR
6939694 6940746 + streptomycin biosynthesis operon regulator
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  • SGR_5932
  • BAG22761.1
  • aphD
6940981 6941904 + streptomycin 6-phosphotransferase
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  • SGR_5933
  • BAG22762.1
  • strB1
6942395 6943441 + scyllo-inosamine-4-phosphate amidinotransferase
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  • SGR_5934
  • BAG22763.1
  • strF
6943485 6944330 + StrF protein
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  • SGR_5935
  • BAG22764.1
  • strG
6944340 6944939 + StrG protein
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  • SGR_5936
  • BAG22765.1
  • strH
6945101 6946255 + putative dTDP-dihydrostreptose--streptidine-6-phosphate dihydrostreptosyltransferase
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  • SGR_5937
  • BAG22766.1
  • strI
6946300 6947346 + putative NAD:myo-inositol oxidoreductase
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  • SGR_5938
  • BAG22767.1
  • strK
6947343 6948692 + putative streptomycin-6-phosphate phosphatase
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  • SGR_5939
  • BAG22768.1
  • strS
6948805 6949941 + putative N-methyl-L-glucosamine biosynthetic aminotransferase
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  • SGR_5940
  • BAG22769.1
  • strT
6950048 6951001 + putative oxidoreductase
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Annotation changelog
MIBiG version Notes
2.0
  • Migrated from v1.4
Detailed domain annotation
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