BGC0000725: alginate biosynthetic gene cluster from Pseudomonas aeruginosa PAO1
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Location: 3,962,825 - 3,979,476 nt. (total: 16,652 nt).
This entry is originally from NCBI GenBank AE004091.2.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000725
Short description alginate biosynthetic gene cluster from Pseudomonas aeruginosa PAO1
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (None)
Loci
AE004091.2
3962825 - 3979476
via
Compounds
  • alginate
Species Pseudomonas aeruginosa PAO1 [taxonomy]
References
Chemical products information
alginate Evidence:
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C22H33O23
Chemical database entries
PubCHEM
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • PA3540
  • AAG06928.1
  • algD
 3962825 - 3964135 (+) GDP-mannose 6-dehydrogenase AlgD
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    • PA3541
    • AAG06929.1
    • alg8
    		 3964275 - 3965759 (+) alginate biosynthesis protein Alg8
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      • PA3542
      • AAG06930.1
      • alg44
      		 3965842 - 3967011 (+) alginate biosynthesis protein Alg44
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        • PA3543
        • AAG06931.1
        • algK
        		 3967025 - 3968452 (+) alginate biosynthetic protein AlgK precursor
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          • PA3544
          • AAG06932.1
          • algE
          		 3968449 - 3969921 (+) Alginate production outer membrane protein AlgE precursor
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            • PA3545
            • AAG06933.1
            • algG
            		 3969942 - 3971573 (+) alginate-c5-mannuronan-epimerase AlgG
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              • PA3546
              • AAG06934.1
              • algX
              		 3971586 - 3973010 (+) alginate biosynthesis protein AlgX
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                • PA3547
                • AAG06935.1
                • algL
                		 3973014 - 3974117 (+) poly(beta-d-mannuronate) lyase precursor AlgL
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                  • PA3548
                  • AAG06936.1
                  • algI
                  		 3974359 - 3975921 (+) alginate o-acetyltransferase AlgI
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                    • PA3549
                    • AAG06937.1
                    • algJ
                    		 3975936 - 3977111 (+) alginate o-acetyltransferase AlgJ
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                      • PA3550
                      • AAG06938.1
                      • algF
                      		 3977184 - 3977834 (+) alginate o-acetyltransferase AlgF
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                        • PA3551
                        • AAG06939.1
                        • algA
                        		 3978031 - 3979476 (+) phosphomannose isomerase / guanosine 5'-diphospho-D-mannose pyrophosphorylase
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                          Biosynthesis information
                          Annotation changelog

                          Entry version: 4

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-10-07
                          Update chemical activity to schema version 2.11
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 3

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2022-09-15
                          Update compound structure (SMILES) for alginate
                          • (ID: H5KVDLSVQ3TJW7SKCDNBDEVC)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          2022-09-15
                          Linked new PubChem id for alginate (pubchem:131704328)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          2022-09-15
                          Updated bioactivity data
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 2

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2019-10-16
                          Migrated from v1.4
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          2019-10-16
                          Updated reference publication(s) (MIBiG Annotathon)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          2019-10-16
                          Updated loci
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                          Entry version: 1

                          Date
                          Changes
                          Submitters
                          Reviewers
                          2015-06-12
                          Submitted
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                          • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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