LOCUS       BGC0000736             15214 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Pasteurella haemolytica capsule biosynthetic gene cluster, partial
            sequence.
ACCESSION   BGC0000736
VERSION     BGC0000736
KEYWORDS    .
SOURCE      Mannheimia haemolytica
  ORGANISM  Mannheimia haemolytica
            Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
            Pasteurellaceae; Mannheimia.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 20:26:42
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..15214
                     /db_xref="taxon:75985"
                     /mol_type="genomic DNA"
                     /organism="Mannheimia haemolytica"
                     /serotype="A1"
     subregion       1..15214
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000736"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..15214
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            complement(478..1125)
                     /gene="cpxA"
     CDS             complement(478..1125)
                     /codon_start=1
                     /gene="cpxA"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 119.4; E-value:
                     3.4e-36)"
                     /gene_kind="transport"
                     /product="CpxA"
                     /protein_id="AAF08240.1"
                     /transl_table=11
                     /translation="MISIRNVSKQYRTNNGWKTILKDINFELKKGEKVGILGRNGAGKS
                     TLIRLMSGVEPPTTGTIERQMSISWPLAFSGAFQGSLTGMDNLRFVSRIYDADFDYVKS
                     FTEEFSELGEYLYEPVKSYSSGMKARLAFALSLSIEFDCYLIDEVIAVGDARFAAKCKH
                     ELFEKRKDRSLILVSHSPASIKEYCDSAMVLEEGIMHTFDSIDNAYNFYNKT"
     gene            complement(1122..1919)
                     /gene="cpxB"
     CDS             complement(1122..1919)
                     /codon_start=1
                     /gene="cpxB"
                     /product="CpxB"
                     /protein_id="AAF08241.1"
                     /transl_table=11
                     /translation="MRYGDNTRFKRSCVIQKRVIHALLMRELITRYGRKNIGFLWLFIE
                     PLLLTLVITVAWKYIKADKFSTLNIIAFMITGYPIAMMWRNASNRAQGAISANLSLLYH
                     RNVRVLDTIFTRVLLEVTGASIAQILLMTIFIAIGWIEMPNDIFYMLCAWILMAFFALG
                     LGLIICTLAHYIEPFGKIWGTFSFFLLPLSGAFFFVHNLPLTAQNIALWFPMIHGTEMF
                     RHGYFGETVITYESISYLIVSDIILLFIGLLCVRSFSKGIEPR"
     gene            complement(1919..3022)
                     /gene="cpxC"
     CDS             complement(1919..3022)
                     /codon_start=1
                     /gene="cpxC"
                     /product="CpxC"
                     /protein_id="AAF08242.1"
                     /transl_table=11
                     /translation="MSKKKKHFLANPLLWLTVIIPTACSGIYYSLFASDIYVSESSFWF
                     RSPNNQSSLTGVGALLQNSGFARSQDDTYSVQEYMRSRTALEQLEAEIPVKRFYSEQGD
                     LLSKFNGLGFNDTQEAFYRYFKERLNIDVDSISGIATLRVRAFNAEEGQKINENLLQQG
                     ETLINRLNERARQDTVEFAEERVKEAEKDVNNTALALSQYRTKNKIYDLPAQSSVQLSL
                     ISTLKSELIRVQTQLAQLKSITPDNPQVAALQMRQKSLKKEIDDQSKQLAGGNTSVATQ
                     TAEYQRLVLANELAQQQLAAAMTSLQNTRGEADRQQLYLEVIGRPSKPDWALEPYRIYN
                     IISTFFIGLILFGVLSLLLASIREHKN"
     gene            complement(3094..4278)
                     /gene="cpxD"
     CDS             complement(3094..4278)
                     /codon_start=1
                     /gene="cpxD"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 287.5;
                     E-value: 1.9e-87)"
                     /gene_kind="transport"
                     /product="CpxD"
                     /protein_id="AAF08243.1"
                     /transl_table=11
                     /translation="MKQKKLNTTLLFITLSLISACSSLPTSGPSYSEILASNENTAETQ
                     LPEVNLIKLDNITVQNLYQEQQSQRFSGFDGSMGVGGYAGTVNVGDILEISIWEAPPAV
                     LFGGTFSAEGQGNGHLTQLPQQMVNKNGTVTVPFIGNIKVAGKTPEVIQNQIVRSLSRK
                     ANQPQALVRIANNLSSDVTVIRQGNSIRMPLSANNERILDAVAAVGGTSENIEDVTVRL
                     TRGNKVRSMAFETLIADPSQNITLRSGDVIALMNTPYSFTGLGAVGNNQQMRFSSKGIT
                     LAEAIGKMGGLIDERSDPRGVFVFRHIPFTQLDYDNQAQWRKKGYAEGMDVPTVYQVNL
                     LKPQSMFLLQRFPIQDKDIVYVSNAPLSEFQKFLRMIFSITTPITGTANTIRAY"
     CDS             complement(4758..5393)
                     /codon_start=1
                     /note="ORF1"
                     /product="unknown"
                     /protein_id="AAF08244.1"
                     /transl_table=11
                     /translation="MLFYLVSDSLTRLSLSNESLVDLGRITSIGNYPFLHNAKNAKFLM
                     VESAWQGYKNRWKYKIASYPDNPERTNEKLVRLVEKAKDQGIPTVFWNKEDSVHFDRFI
                     DSAKHFDHIFTVDQNAIARYREVVPATTTVNVGMFPVQPKIHNFQGFNFKHLAANFVGS
                     YSHHIHNKRRERQDMLFGAALKAGLPVTIFDRNSDRKSENYRYPKNSF"
     CDS             complement(4758..6200)
                     /codon_start=1
                     /note="ORF2"
                     /product="unknown"
                     /protein_id="AAF08245.1"
                     /transl_table=11
                     /translation="MNIKDLLKEISFKAVINDLNFSSCLYIKPNTSKLYVILNGALIKE
                     PRNPLIYHRHSWHLEFDGSVLYIADPTLFKYESINLAWYVGDKDTDLYPYLAEFVTSVA
                     THLNVETDHIVTYGSSGGGFAALQLGARIGNGVVTVCINPQTNIMKYVPSHRNAFLNAC
                     FDFNAEEYDSLSNQEKFNALVLLKENTSKILYIQNTQDEFHHKWHFLPFLELKGIDLSE
                     IEKTHWREQQSKDVKVILYSHESGHAAEPKEMIPEILSAVDQLIAAKMLFYLVSDSLTR
                     LSLSNESLVDLGRITSIGNYPFLHNAKNAKFLMVESAWQGYKNRWKYKIASYPDNPERT
                     NEKLVRLVEKAKDQGIPTVFWNKEDSVHFDRFIDSAKHFDHIFTVDQNAIARYREVVPA
                     TTTVNVGMFPVQPKIHNFQGFNFKHLAANFVGSYSHHIHNKRRERQDMLFGAALKAGLP
                     VTIFDRNSDRKSENYRYPKNSF"
     CDS             complement(6212..7279)
                     /codon_start=1
                     /note="ORF3"
                     /product="unknown"
                     /protein_id="AAF08246.1"
                     /transl_table=11
                     /translation="MKFILFDSILERHLGESLKRALESLGHQAVFTDLILHGHSMIYKQ
                     ADIDFMWKKVKDICDEKADMFISFRPMNLTTEMLEYIGKRMKTAIWLSDDPVLYKTCYS
                     QVVNHYDVLLHCGYKEVMDFYEANNHPKGFNFPFWTDHVAFPSVYNPLHSDYEIAFLGN
                     MNGQVRRKRYMELASLPFTKKVFGLIDSDPLAMHGGFINEAYLHTKRVTEVLSKAKVGV
                     SIPQFFTEYNGLDYDYPELAGLGYFQFPSRVIQDAASGLPIAAVGDERMKEVYPEIFVG
                     NSITELEPYIKQICEDYDFALSESAKILTRFRKNYSALSRAMMLIDLVENLDKLQSQTT
                     QERAILFTKYKAQYN"
     CDS             complement(7281..9401)
                     /codon_start=1
                     /note="ORF4"
                     /product="unknown"
                     /protein_id="AAF08247.1"
                     /transl_table=11
                     /translation="MKNKQQYRKSTINNTNASQQNSGEVLNSVNYQTLLEDYLNKISFS
                     NRQFIDERKTEHNKKLKELENKVSSLEQTNHVQQQDISRLNILLEQKNIEENRNLERMI
                     SYQLGYALINACKSFSGFISLPSELLKIRKLAKDKKQQKLLPSSPVANTPKQQTALVTS
                     APARSQSIDLTRGLTLLDPISELCWADAFTGYPLVRKSYADHIAGSTCKFAFFESAWQA
                     NKGSWIYAFTSPGLKHNNAQALLDAIQKLKDKSIPIIFWNKEDPMHYEMFKPIAEKVDY
                     VFTTDQLVVDKYKKELGHSNIWALPFAAPIKVTNPIGRFSLDTETVCFAGTYYAQNHEN
                     RKKQMDMLLPALLAYNGCIYDRASKDTSGKYAYPEQYTHLIREGVNFNEIVKLYKKFKV
                     FLNVNTITQSTTMMSRRVYELLASGTPVVSTPSKAITAQFPGIVITVNNEKEAELAVHK
                     LLTDSYYWHKQSMLGIREVMSKHTYENRWEFACSVINNEPIKEKTPSVRIIAVYHNYLD
                     LAIYIDSLIHQNNVDIKEVVLLISSSLVLDKELLDGYSDKVKVVTLSEFNLKNYLDDEV
                     SYTYFTDDNVLNYRNSIYGLVATLNYCNTEAVTRRLYYKLSSLNKIMDFSITQEDWYRS
                     VTETQRNCVLIKNSAIEDYSINLTANKIQAKNSPIFIADPFNVLYIDDKKLLKGRDSLL
                     KLVYKTSPYLGV"
     gene            complement(9405..10676)
                     /gene="wecB"
     CDS             complement(9405..10676)
                     /codon_start=1
                     /gene="wecB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1152:nucleotide sugar dehydrogenase (Score: 428.7;
                     E-value: 3.6e-130)"
                     /gene_kind="biosynthetic-additional"
                     /product="UDP-N-acetylglucosamine-2-epimerase"
                     /protein_id="AAF08248.1"
                     /transl_table=11
                     /translation="MSNFNTISVVGLGYIGLPTATVFAQHGLNVIGVDVNQHAVDHINQ
                     GKIHIVEPDLDVAVHQCVSSGKLKATLTPEPAEAFLIAVPTPFKGQDYEPDLSYIQAAC
                     KAIAPVLEKGNLVILESTSPVGATEQMAEWLAEYRPELSFPQQAGEDSDIRIAHCPERV
                     LPGQVMHELIENDRIVGGMTNKCSVQAVNLYKTFVKGDCIVTNARTAEMCKLTENSFRD
                     VNIAFANELSIICDRLDINVWELIALANRHPRVNILQPGCGVGGHCIAVDPWFIVNKTP
                     DLAKIIRTGREVNDHKPEWVISKMNEAVIYALQKTGKSIDQIKIACLGLAFKPDIDDLR
                     ESPALKITEKLAEKYPNQVFAVEPNVEELPKKLANKNISLISVDEALEVADVVVVLVDH
                     SEFKLVKPVFLNDICVVDTKGIWR"
     gene            complement(10691..11809)
                     /gene="wecC"
     CDS             complement(10691..11809)
                     /codon_start=1
                     /gene="wecC"
                     /product="UDP-N-acetylmannosamine dehydrogenase"
                     /protein_id="AAF08249.1"
                     /transl_table=11
                     /translation="MRYLIVFGTRPEAIKMAPLVEGFKKSGLNFKVCVTAQHRQMLDQV
                     LELFEITPDYDLDIMSNKQTLSTVTSAILEKIQPVIAEYKPTTIFVHGDTATTLASSLA
                     AYYNQIDIAHIEAGLRTHNIYSPWPEEGNRKLTAALAKYHFAPTQSTKKNLLNENIAEG
                     TIYVTGNTVIDALFLACKKLDENIDLLSSLQEKFSYIKSKRTILITGHRRENFGNGFEN
                     ICKAVSTLASDFPDVQFIYPVHLNPNVREPVNRLLADKSNVHLIEPCDYLSFVYLMRES
                     YLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVEAGTVKLCLGTAQSEIIKQVTELLN
                     DQAAYTKMSEAHNPYGDGTAVKQILSVFQSKQ"
     gene            12042..14132
                     /gene="phyA"
     CDS             12042..14132
                     /codon_start=1
                     /gene="phyA"
                     /product="PhyA"
                     /protein_id="AAF08250.1"
                     /transl_table=11
                     /translation="MLSYLVFFSKIIKIPNLKGFLPHCEIRRKTSCGKNLYCSKKTEPN
                     HRLGASSFSGGIKSLCTKTSTSLYCIRRRFLRSLGLGVKGYPPFSLVYDDIGIYYDTTC
                     PSRLEKLLLEKPLQDQEQIKLAERALSQILTYGLSKYNHALDFSEIPSAKEKIVLVIDQ
                     TFGDMAVKYGQASEVDFNKMLETAISENPEAQIWVKTHPDVLSGKKKGYLTDLPQYTDR
                     VRIITEDVNPASLIKLCEKVYCVTSQMGFEALLLGKKVVTFGVPWFAGWGVTDDRNEAV
                     QLLVQQNRRKDRSLLQLFYAAYFDYSRYINPNTGEKGSIFDVIDYLYKAKRLNQRLSGN
                     LYCIGMSLWKQAVIKPFFNLPQCRLHFVRSLNSLKKRPLADNAKILVWSNGKADVLQFA
                     QQNNIPLLRMEDGFIRSVGLGANLVAPLSLVVDDLGIYFNAENTSRLEQILLSAEHFSE
                     TDLSYAETLRQKLVASHIGKYNVGGGDVKFNAQGKKIILVPGQVEDDASIKSGSPQIKR
                     NLDLLKKVRELNPSAYIIYKPHPDVVSGNRVGQIPTAETRRFADQMVDNANILDCILIA
                     DEVHTMTSLAGFEALLRGKKVHCYGLPFYAGWGLTEDRLKSARRGKSLTLSQLIAATLI
                     YYPLYVDPISRQFIDANQAIHILSQQKRNLTNQRIKRSWVSKQYGKLQHLYRAFKYASH
                     TK"
     gene            14155..>15214
                     /gene="phyB"
     CDS             14155..>15214
                     /codon_start=1
                     /gene="phyB"
                     /product="PhyB"
                     /protein_id="AAF08251.1"
                     /transl_table=11
                     /translation="MEHYLDELIINSQRILLLQGPIGSFFTEFARWLESEQKEVFKLNF
                     NGGDEYFYPNNSPNTFPYYDSLDNFEAYLIQFCQTHQIDNILCFGDNRYYHKVAKNVCL
                     KLKLVFWAFEEGYFRPEYITLEKWGVNAFSPIPKNHTFFLPYAELPVVSEPEKVSKGFR
                     CMAGKAIPYYWNAYKKRKAYAKYQHHRFLNLKYYLNLWTRLELSEYVLVTYKGFAKRVE
                     KGEFGEFFIVPLQVYDDTQVRIHSEQKSVERFLREVLNSFAKFAPAHLNLIIKHHPMDR
                     GFIDYKMVIYEFLEQYPQLNGRVFYIHDVPLPVFLRYGKGMVTLNSTSGLSALLHNMPV
                     KTLGRANYDFEGL"
ORIGIN
        1 gtatcaagcg caaaattcat cggtttcaga acttagccaa aataattttg aaaatgtaga
       61 tgaaaatgtg gcaagtaaag tgattttaca agcaatgatt gccgctgctg cttcagatgg
      121 tgctattact gaagaggaaa aagcagctat tgtttcccaa gttggagatg aggctgaagt
      181 cattgagtgg attcgtcaag aaatggacac tccggctaca gttgaagaga ttgccgaagt
      241 aggtaatgac caagcattgg ctacacaagt ttacttagct tcccgtgcag tatgcagaga
      301 tttagaacgc aaagaaatcg ttttcttagc taatttagct gatgctttag gtttagctga
      361 ggcattagtt gaacaattag aaaaagacgc aggtttctaa ttttcagttt tagtaacaag
      421 cggttatatt ttgagagttt tttgcgaaaa acttgtgaaa tataaccgct tgttctttta
      481 tgttttattg tagaaattat aagcgttatc tatagaatca aaagtatgca tgataccctc
      541 ttctaaaacc attgcagaat cgcaatattc tttaattgag gctgggctat gagaaactaa
      601 aatcaatgaa cggtctttcc gtttttcaaa aagctcgtgc ttacatttgg cagcgaatcg
      661 agcatcgcct actgcaatca cttcatcaat taagtaacaa tcaaattcaa tagaaagcga
      721 taatgcaaag gctaaacggg ccttcatacc agaagaatag ctttttaccg gttcatataa
      781 atattcaccg agttctgaaa attcttcggt gaaagatttt acatagtcaa aatcagcatc
      841 ataaattcgg ctgacgaaac gaagattatc cattccggtc aaactaccct ggaatgcacc
      901 actaaatgcc agtggccaag aaatggacat ttgacgttca atcgtacctg ttgttggagg
      961 ttctactccg ctcattaaac ggattaaggt tgattttcct gcaccattgc gccctaaaat
     1021 ccccactttt tcgccttttt tcagctcaaa atttatatct tttaatatgg ttttccaacc
     1081 gttattagtt cgatattgct tacttacatt tctaatacta atcatcttgg ttctatccct
     1141 ttactaaaac ttctcacaca aagcagtcct ataaatagaa gaataatatc acttactata
     1201 agataactaa tgctctcata ggtaattacc gtttcaccaa aataaccatg tctaaacatt
     1261 tctgtaccat gaatcattgg aaaccataag gcaatatttt gagcagttag cggtaaatta
     1321 tggacaaaga agaatgcacc agaaagagga agtagaaaga agctgaatgt tccccaaatc
     1381 ttaccaaaag gttcaatata atgtgctaaa gtacagataa ttaaacctaa acctaaggca
     1441 aaaaatgcca ttaatatcca agcacagagc atatagaaaa tatcgttagg catttctatc
     1501 caaccaatag cgataaatat agtcattaag agaatttggg cgatagatgc gccagtaact
     1561 tctaataaaa ctcgagtaaa tatcgtatct agcactctca catttctgtg gtaaagcaaa
     1621 cttaagtttg ctgatattgc tccttgagct ctattagagg catttctcca catcattgcg
     1681 atagggtagc ctgtaatcat aaaagcgata atatttaaag ttgaaaactt atctgctttt
     1741 atatatttcc aagcaacagt aatcactaac gttaacaata atggttcgat aaaaagccat
     1801 aagaagccaa tatttttacg cccataacga gtaattaatt ccctcattaa aagggcgtga
     1861 atcacccgtt tttgaatcac acaggaacgt ttaaaccttg tattatcacc atatcgcatt
     1921 agtttttatg ctctctaata cttgctagta acaaacttaa tactccaaat agaattaagc
     1981 cgataaaaaa agttgatata atattataaa ttctgtaggg ttctaatgcc caatctggtt
     2041 tgcttggcct accaattacc tctaaataaa gttgttggcg atcagcttca cctcgtgtat
     2101 tttgtaatga agtcattgct gctgcaagtt gttgctgagc taattcgtta gcaagaacca
     2161 aacgttgata ttcagcagtt tgcgttgcta cagaagtatt acctcctgca agttgtttgg
     2221 actgatcatc aatttctttt ttcaaacttt tttgacgcat ttgtaatgcg gctacctgag
     2281 gattatccgg cgtaattgac ttcaattgtg ctaattgtgt ttgtacccga attaattcac
     2341 tttttaaggt agaaattaat gagagctgaa cgctggattg tgccggtaaa tcataaattt
     2401 tatttttagt tcgatattgg cttaatgcta acgcagtatt attgacgtct ttttcggcct
     2461 cttttacacg ctcttctgca aactcaaccg tatcttgtct tgctctttca ttaaggcggt
     2521 taattaatgt ttccccttgc tgtaataaat tctcgttaat tttttgtcct tcttctgcat
     2581 taaaagcacg aacgcgtagc gttgcaatac ctgaaataga atcgacatca atattcagac
     2641 gttctttaaa ataacgataa aatgcttctt gggtatcgtt aaatcctaaa ccgttaaatt
     2701 tgcttagtaa atcaccttgc tcactataaa aacgctttac cggaatttct gcttcaagtt
     2761 gttctaatgc ggtacgggaa cgcatatatt cctgaactga ataggtatca tcttgagaac
     2821 gggcgaaacc ggagttttgc aataaagcac caacgcctgt taagctcgat tgattattgg
     2881 gcgaacgaaa ccaaaagcta gattctgaaa cataaatatc agaggcaaat aaggaataat
     2941 aaattccaga acaagcagtt ggaataatta cagttagcca caacaaaggg ttggctaaaa
     3001 aatgtttttt cttctttgac ataaaatcct caacgaaaag tgttacaagc ggtcattttt
     3061 taatgatttt ttaccatttt atctatgagc taattagtac gctctaattg tattagctgt
     3121 acctgtaatt ggtgtagtaa tggagaaaat cattctcaag aatttttgaa attcagacag
     3181 tggagcattc gacacatata caatatcttt atcttgaata gggaaacgct gcaataaaaa
     3241 cattgattgc ggttttaata aattcacctg ataaacagtt ggaacgtcca ttccctctgc
     3301 ataacctttt ttacgccatt gagcttggtt atcgtaatct aattgtgtaa aaggaatatg
     3361 gcggaatacg aacacaccac gagggtctga acgctcatca attaatcctc ccattttacc
     3421 gatagcttca gcaagggtaa tgcctttact tgaaaaacgc atttgttgat tattacctac
     3481 tgctcctaat ccggtaaagc tataaggagt attcattaaa gcaataacat cacctgaacg
     3541 taatgtaata ttttgtgagg ggtcagcaat taatgtttca aacgccattg aacgcacttt
     3601 atttccacgt gttaaacgaa ctgttacatc ttcaatattt tcgcttgtac cacctactgc
     3661 cgcaactgca tctaaaatac gctcattatt ggcacttaat ggcatacgaa tgctatttcc
     3721 ttggcggata accgtaacat cagacgacaa gttattcgca atacgaacta atgcttgagg
     3781 ttgattagct ttacggctca agctccgaac aatttgattc tgaattactt caggtgtttt
     3841 tccagcaact ttaatattac cgataaaagg cacagttacc gttccatttt tgttcaccat
     3901 ttgctgaggt aattgggtta aatgcccatt accttgccct tcagcactaa atgttccacc
     3961 aaatagcacg gcaggtggcg cttcccaaat ggatatttct aatatatcgc ctacattaac
     4021 tgttccagca taaccaccca cacccattga gccatcaaat cctgaaaaac gttgagattg
     4081 ttgctcttgg tataagtttt gtacggtgat gttatctaac ttgattaaat tgacttcagg
     4141 caactgcgtt tcagctgtat tttcattact tgctaagatt tcgctatagc ttgggccgga
     4201 cgttggtagg ctagagcagg ctgaaattaa tgataatgtt ataaataata atgtagtatt
     4261 taattttttt tgtttcatta tagtacctat aattaatttg gattcatcct aaataacatg
     4321 actaaatttc ccctaattaa ttactcgaaa tagaaaataa tttcttggca gagagttttt
     4381 aataatgcta tttaagttac ctatatacaa ctttctgtat ttgggataag aaatgttccc
     4441 aagtaaagtt actcaataca aattcagagc ctgcaatcgc tttattcaaa tcatcacgag
     4501 aagcacctcg ttttaaacgt tggaataatt ctatagcctc atcttcactt tgtacgatat
     4561 gacaatattc tttaaatata ttgtcgatag ccatacttgg tgtagagact aatattcctc
     4621 cataagctaa tatttcaacg actctgcgag aaaacatcgt aggggaatct tcgacagtat
     4681 taatattcaa agaaacaaga taatcacgat aaatattagc agtttcagta taactaacat
     4741 taggttgaac atttaaatta aaagctattt tttgggtaac gataattttc cgattttcta
     4801 tcagagtttc tatcaaagat ggttaccgga agacctgctt taagtgctgc accaaacaac
     4861 atatcctgtc tttctctacg cttattgtgg atatgatgac tgtaactccc tacaaaattt
     4921 gcggcaaggt gtttaaaatt aaatccttga aagttatgga ttttgggctg aacagggaac
     4981 attccgacat tgacggttgt tgtcgcaggc actacttccc tataacgagc aatggcattt
     5041 tgatctacgg taaaaatatg atcaaaatgc ttcgccgaat caataaatcg atcaaaatgc
     5101 acagaatctt ctttgttcca aaagaccgtt ggaatgcctt gatccttcgc tttttctact
     5161 aaacgaacca acttttcatt ggttcgttca ggattatcag gataagaggc aattttatat
     5221 ttccaacggt ttttgtagcc ttgccaggcg gattcgacca taagaaattt agcattcttt
     5281 gcattatgca agaaaggata atttcctata gatgttattc ttccaagatc aactaggctt
     5341 tcatttgata atgaaagcct agttaaagaa tcagatacca aataaaacag cattttagct
     5401 gctatcagtt gatcaacagc ggataatatc tcgggaatca tttccttagg ttcagctgca
     5461 tgacctgatt catgagaata caaaataact tttacatctt tgctctgttg ttctctccaa
     5521 tgggtctttt ctatttccga tagatctatc ccctttaact ctaggaatgg gaggaaatgc
     5581 catttatgat gaaattcatc ctgagtattt tgaatataca aaatctttga tgtattttcc
     5641 ttaagtaata ctaaagcatt aaatttctct tgattagaaa gactatcgta ctcttccgca
     5701 ttaaagtcaa agcaagcgtt taaaaaggca ttacgatgac ttggtacata tttcatgatg
     5761 ttggtttgtg gattaataca aacggtaact acaccgtttc caattcttgc tcccaactgt
     5821 aatgcagcaa atccaccacc acttgaacca taagtaacaa tatggtctgt ctcaacattc
     5881 aaatgtgtag caacagaagt tacaaattca gctaagtatg gatataaatc agtatcttta
     5941 tctccaacat accaagccaa attaattgat tcatatttaa ataatgttgg atctgcgata
     6001 tatagaactg agccatcaaa ttctagatgc caactatgtc tatgataaat taagggattt
     6061 ctgggttctt tgattaatgc accatttaat atcacatata attttgatgt attaggtttg
     6121 atatatagac acgatgaaaa attaagatca ttaattacag ctttaaagct gatctcttta
     6181 agtaagtctt taatattcat aaagtttact cctagttgta ttgagcttta tatttagtaa
     6241 ataaaattgc gcgctcttgt gttgtctggc tctgtagttt gtctaaattt tctaccaaat
     6301 caatcaacat catggcacgg gataaggcag aatagttctt tctaaatcta gttagaattt
     6361 tagccgattc tgatagtgca aaatcataat cttcacaaat ttgtttaatg tacggctcca
     6421 gctctgtaat actattgcca acaaagattt caggataaac ttccttcatt ctctcatcac
     6481 caaccgctgc aataggtaac ccacttgcag catcttggat aactcgacta ggaaattgga
     6541 aatatcctaa acccgccaat tcaggataat cataatctaa accattatat tcggtaaaga
     6601 attgtgggat actcacccca acttttgcct tagataaaac ctctgttaca cgttttgtat
     6661 gtaaatatgc ttcattgata aatccaccat gcattgctaa tggatctgaa tctattaaac
     6721 cgaatacttt tttggtaaat ggtaatgaag ccaattccat gtatcttttg cgtctaactt
     6781 gcccattcat attacctaaa aatgcaatct cataatcaga atgaagcggg ttatatacac
     6841 ttggaaatgc tacatgatct gtccaaaacg gaaaattaaa gccttttgga tggttattag
     6901 cttcataaaa atccataact tctttatatc cgcaatgtaa taatacatca taatgattta
     6961 ctacttgaga atagcaagtt ttatataaaa cagggtcatc tgaaagccaa atagcggtct
     7021 tcattcgctt gcctatatac tcaagcattt ctgtcgttag attcatcggc cgaaatgaga
     7081 taaacatatc tgctttttca tcacaaatat cttttacttt tttccacatg aaatctatgt
     7141 ccgcttgttt ataaatcata gaatggccgt gcaaaattaa atctgtaaat actgcttgat
     7201 gccctaacga ctccaaagct ctttttaaac tttcgcccaa atgacgttct aaaatagaat
     7261 caaataaaat aaacttcata ttaaacccct aaatatggag aagtcttata aaccaattta
     7321 agtaaggaat ctctaccttt caataacttt ttatcatcta tatatagcac attaaatgga
     7381 tcagctataa agataggtga atttttagcc tgaattttat tggccgtaag attgattgaa
     7441 taatcttcaa tagcactatt tttaattaaa acacaattac gttgagtttc tgtaacactt
     7501 ctgtaccagt cttcctgagt aattgaaaag tccattattt tattcaatga tgataattta
     7561 tagtacaatc ttctggttac tgcttctgta ttacaataat taagtgttgc taccaatcca
     7621 taaatagaat tacgataatt taggacatta tcatcggtga aataagtgta agaaacttca
     7681 tcatctaaat agtttttcag attaaactca gaaagagtaa ctactttcac tttatcggaa
     7741 taaccatcta ataattcttt atctaaaaca agtgaagatg aaataagtaa tacaacctct
     7801 ttaatatcaa cattattttg atgaattaga gaatctatat agatagctaa atctagataa
     7861 ttatgataaa ccgcgataat tcgaacacta ggtgtttttt cctttattgg ttcattattg
     7921 attacactac acgcaaattc ccaacgattt tcataagtat gttttgacat tacttcacgt
     7981 atgcccagca tggactgctt atgccaataa tagctatctg tcagtaattt atggacagca
     8041 agctcagctt ctttctcatt atttacagta ataacaatgc cagggaattg tgccgtaata
     8101 gctttagatg gcgtagatac aacaggtgtg ccgctagcta gaagttcata cacacgtctt
     8161 gacatcattg tggttgattg agtgatggta ttaacattta aaaatacttt aaatttctta
     8221 tacaacttaa ctatctcatt gaaatttacc ccttctcgga taagatgagt gtattgttca
     8281 ggataagcat atttgccact tgtatcttta gatgctctat cataaataca gccgttgtaa
     8341 gccaataatg caggtaacaa catatccatc tgttttttac gattttcatg attttgagca
     8401 taatatgttc cagcaaaaca aactgtttct gtatcaagag aaaatctgcc aattggattg
     8461 gttactttaa ttggggcagc aaaaggcaaa gcccaaatat ttgaatgccc aagttctttt
     8521 ttatatttat ctacaaccaa ttgatctgtt gtaaaaacat aatctacttt ttctgcgatt
     8581 ggcttaaaca tctcataatg cattggatct tctttattcc aaaaaatgat aggaatgctt
     8641 ttatctttta gtttctgaat tgcatctaac aatgcttgag cattattatg ttttaagcct
     8701 ggtgaagtaa aagcatagat ccatgaccct ttatttgcct gccaagcact ttcaaaaaaa
     8761 gcaaatttac acgtgctgcc agcaatatga tcagcataag attttctaac taaaggatac
     8821 cctgtaaagg catctgccca gcataattca gaaataggat ccagtagtgt caatcctctt
     8881 gtcaagtcaa tagattgaga tcgggcaggt gcacttgtaa ctaatgcagt ctgttgcttt
     8941 ggtgtatttg caacagggga agatggcaat aatttctgct gtttcttatc cttagctaac
     9001 ttcctgattt ttaataattc tgaaggcaag gatataaaac cactaaatga tttacaagcg
     9061 tttattaaag catatcctaa ctgataagaa atcattcttt caagatttct attttcttca
     9121 atgttctttt gctctaacaa aatatttaat ctggatatgt cttgctgttg aacatgatta
     9181 gtttgctcaa ggctgcttac tttattttct agctccttga gctttttatt atgctcagtt
     9241 ttacgctcat ctataaactg ccgattacta aaactaattt tatttaaata atcttccagt
     9301 aatgtttgat aattgacaga atttaatact tcgcctgaat tttgttgtga tgcattagta
     9361 ttgttaatag tggatttacg atattgctgt ttgtttttca tcacttatct ccaaattcct
     9421 ttagtatcca ccacacaaat atcattcaaa aacacaggtt tgactagttt aaattcgcta
     9481 tgatccacca aaacaactac aacatcagct acttccagag cttcatcaac agaaatcaaa
     9541 gaaatgttct tgttagccaa ttttttcggt agctcttcaa cattcggctc aactgcaaat
     9601 acttgatttg gatacttttc cgccaatttt tcagtaattt ttaatgccgg actttcacgc
     9661 aaatcgtcaa tatcaggctt gaatgccaac cctaaacaag caattttgat ttgatcgata
     9721 gatttacctg ttttttgtaa ggcataaatt accgcttcat tcatctttga gataacccat
     9781 tcaggtttat gatcgtttac ctcacgacca gtgcggataa tttttgccaa gtcaggagtt
     9841 ttattcacaa taaaccaagg atctacagca atgcagtgtc cacctacacc acaacccggt
     9901 tgtaagatat tgactcgagg gtgtctgtta gccaaagcaa ttagttccca tacattaata
     9961 tctaggcgat cacaaataat agaaagctca tttgcaaaag cgatattgac atcacggaaa
    10021 ctattttcgg ttaatttaca catttctgcg gtacgggcat tggtaactat acagtcgcct
    10081 tttacaaaag ttttgtataa attgaccgct tgcacagagc atttatttgt cataccaccc
    10141 acaatacggt cgttttcaat caattcatgc atcacttgtc ctggtagaac tcgttctggg
    10201 caatgggcga tacgaatatc agaatcttca cctgcttgct gagggaagct tagctctgga
    10261 cggtactcgg caagccactc agccatctgt tctgttgcac caaccggaga ggttgattct
    10321 aaaatgacta aattaccttt ttccagcaca ggtgcaattg ctttgcaagc agcttgaata
    10381 taacttaaat caggctcata atcctggcct ttaaaaggcg ttggtacagc aattaaaaat
    10441 gcttctgctg gttcaggtgt cagtgtggct tttaattttc cgctagatac acattggtga
    10501 acagcaacat ctaaatcagg ctcgacaatg tgaattttcc cttgattgat atggtctacg
    10561 gcgtgctgat taacatctac gccaattaca tttagaccgt gttgggcaaa tacagtggcg
    10621 gttggtaagc caatatagcc taagcctact actgaaatgg tattaaagtt cgacatacat
    10681 ttatccctta ttattgtttt gattgaaata ctgagagaat ttgtttcaca gctgtgccat
    10741 cgccataagg gttgtgagcc tcagacattt ttgtataagc agcttgatca ttgagtaact
    10801 cagtaacttg tttaataatt tcagattgtg cagttcccaa acaaagtttt actgttccgg
    10861 cttctacagc ttccggtctt tctgttgtgt ctctcattac taataccggt tttcctaatg
    10921 atggggcttc ttcttgaata cctccggagt cagttaagat aaggtaagac tctctcatta
    10981 aataaacaaa ggagagatag tcgcaaggct caatgagatg cacattggat ttatccgcta
    11041 ataggcgatt gaccggttct cttacatttg ggttgaggtg tacggggtag ataaattgaa
    11101 cgtcagggaa atcagacgct aatgttgaaa cggctttaca gatgttctca aaaccattac
    11161 cgaaattttc gcggcgatgt ccggtgatca aaatagtacg cttacttttt atataagaaa
    11221 atttctcttg tagcgagctt aataaatcaa tattttcatc taattttttg caagcgagga
    11281 ataaggcatc aattaccgta ttacccgtta cataaatggt gccctcagca atattttcgt
    11341 tgagtagatt tttcttggtg ctttgtgttg gtgcgaaatg gtattttgcc aaagcagctg
    11401 ttaatttgcg attgccttct tccggccaag gagagtagat attatgcgtt cttagacctg
    11461 cctcaatatg agcgatatca atttggttgt aataggctgc taatgaagag gcaagagtgg
    11521 ttgctgtatc gccatgaaca aaaatagtag ttggtttgta ttcggcaata acaggttgaa
    11581 ttttttctaa aatagcagaa gttacagtag aaagtgtttg cttattgctc ataatatcca
    11641 ggtcataatc tggagtaatt tcgaataatt ctaaaacttg gtccagcatt tggcggtgct
    11701 gagcagtaac acagacttta aaatttagac cgcttttctt aaagccctca actaagggag
    11761 ccattttgat tgcctcagga cgagtaccga agacgatgag atagcgcatt tattactcct
    11821 ttaaaaatat agataaaact aaaatacact agatgtaagt aattttgtta aattagttat
    11881 aaagatcgtg ttcattataa tgtttttatg gagttaggtg tataaaaact tttactttgt
    11941 agatatttta tgtaaattct tgtaagtatc cggtaggtta gaaattatca tgttatctgc
    12001 tatggtacaa tacataaata cgaatatgag attaattttt tatgcttagc tatttagtgt
    12061 tttttagtaa aattataaaa atccctaatt taaaaggttt tttacctcat tgtgaaatta
    12121 ggcgaaaaac ctcttgtggg aaaaaccttt attgctcaaa aaagaccgaa ccaaatcatc
    12181 ggctgggggc ttcgtccttc agcggtggga tcaagagctt atgcacaaaa acatcaactt
    12241 ccctatattg cattagaaga cgctttttac gctcactagg gctgggtgta aaaggctatc
    12301 cgccattttc tttagtttat gatgatatag gtatttatta cgataccacc tgtccttctc
    12361 gtttagaaaa gttattgctt gaaaaacctt tacaggatca agagcaaatc aagcttgcag
    12421 agagagcatt atctcaaatc ttaacttacg gactttctaa atataatcac gcactagatt
    12481 ttagtgaaat cccctctgcc aaagaaaaaa tcgtgttagt tattgaccaa acctttggtg
    12541 atatggcggt gaaatatggt caagcgagtg aagtggattt caataaaatg ttggaaacgg
    12601 caatcagtga gaatccagag gctcaaattt gggtaaaaac tcaccccgat gtattaagtg
    12661 gcaagaagaa aggctatttg accgatttac ctcaatatac tgatagggtc agaattatta
    12721 ctgaagatgt gaatccggca agtttgatta aattgtgtga gaaagtctat tgcgtaactt
    12781 cgcaaatggg gtttgaggca ttattattag gtaaaaaagt ggttaccttt ggtgtaccgt
    12841 ggtttgccgg ttggggggta acagatgatc gtaacgaagc ggttcaacta ttagttcaac
    12901 aaaatagacg gaaagatcgt tcattactgc aactttttta tgctgcgtat tttgattaca
    12961 gccgttatat taatccgaat accggtgaga aaggctctat ttttgatgtc atcgattatc
    13021 tatataaagc caaaagatta aatcagcgct taagtgggaa tctatactgt attggtatgt
    13081 cgctatggaa acaggcggta attaagccgt tttttaattt gccacaatgt cgattacatt
    13141 ttgttcgttc gctaaattct ttaaaaaaac gaccgcttgc agataatgca aaaattttag
    13201 tttggagcaa tggcaaagcg gatgtcttgc aatttgcaca gcagaataat attccattgt
    13261 taagaatgga agatggattc attcgctctg tcggactagg cgctaattta gttgcaccgc
    13321 tttctttagt agtcgatgat ttaggcattt attttaatgc agagaacact tcacgattag
    13381 aacaaatttt attgagtgca gagcattttt ctgaaactga tttgtcttat gctgaaacat
    13441 taaggcagaa attggtggct agccatattg gaaaatataa tgtgggcggt ggcgatgtaa
    13501 aatttaatgc tcaaggtaaa aaaataattc ttgtaccggg gcaggtagaa gatgacgctt
    13561 cgatcaaatc aggttctcca caaattaaaa gaaatctgga tttactgaaa aaagtgaggg
    13621 aattaaaccc tagtgcctat attatttata agcctcaccc tgatgtggta agtggtaatc
    13681 gagtcggtca gattcctacg gcagaaacac gcaggtttgc ggatcagatg gtggataatg
    13741 ccaatatttt agattgtatt ttaattgcag atgaagtgca tacaatgaca tctttagccg
    13801 gtttcgaagc attattaaga ggtaaaaaag tgcattgcta cggattacct ttttatgctg
    13861 gttggggatt gacggaagat agattgaagt cggcacgcag aggtaaatct ttgacattat
    13921 ctcagttaat tgccgcaaca ttgatatatt accctctgta tgttgatcct ataagcaggc
    13981 agtttattga tgccaatcaa gcgattcata tattgtcaca acagaaacga aacctaacca
    14041 atcaaaggat taaacgttct tgggtgagta aacaatatgg aaaattacag catctttatc
    14101 gtgcgtttaa atatgcttcc cacactaaat aagcgtagag ggtaggaaat taagatggaa
    14161 cattatttag atgagctaat catcaatagc cagagaattt tattgttaca aggcccgata
    14221 ggctcttttt tcactgagtt tgcccgttgg ttagaaagtg agcaaaaaga ggtcttcaag
    14281 ttaaatttta atggcggaga tgaatatttc tatccaaata atagcccgaa tacttttcct
    14341 tactatgata gcttagataa ttttgaagcc tatttaattc agttttgcca aactcatcaa
    14401 atagataata tcttatgttt tggcgataat cgttattatc ataaagtggc taaaaacgtt
    14461 tgcttgaagt taaagttggt cttttgggcg tttgaagaag ggtactttag gccagaatat
    14521 attacgttgg aaaaatgggg tgtaaatgct ttttctccaa tccctaaaaa tcacactttc
    14581 tttttgcctt atgccgagtt accagtagtc agtgaaccag aaaaagtatc taaaggcttt
    14641 agatgtatgg cgggaaaagc aatcccgtac tattggaatg cctataaaaa acgtaaagca
    14701 tacgcaaaat atcagcatca tcgttttctg aatctcaaat actaccttaa tttatggaca
    14761 aggctggaat taagcgaata tgtattggtt acatataaag gctttgccaa gcgggtagaa
    14821 aaaggagagt ttggtgaatt tttcattgtg cctctacaag tttatgatga cactcaagtg
    14881 aggattcata gtgaacaaaa aagtgtagag cgttttttaa gggaagttct gaattccttt
    14941 gccaaatttg caccggcaca tctcaattta attattaagc atcacccgat ggatagagga
    15001 tttatagatt ataaaatggt gatttatgaa ttcttagagc aatatcccca attaaacggt
    15061 agagtttttt atattcacga tgtgccgtta cctgtctttt tacgttatgg gaaaggaatg
    15121 gtgactttaa attcaaccag tgggctttct gcattgctcc ataatatgcc ggtcaaaacc
    15181 ttaggtagag ccaattatga ttttgaggga ttaa
//
