LOCUS       BGC0000740              4888 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus agalactiae strain 090 capsular polysaccharide
            biosynthesis gene cluster, partial sequence.
ACCESSION   BGC0000740
VERSION     BGC0000740
KEYWORDS    .
SOURCE      Streptococcus agalactiae
  ORGANISM  Streptococcus agalactiae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:08:11
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..135
                     /gene="cpsIaD"
     CDS             <1..135
                     /codon_start=1
                     /gene="cpsIaD"
                     /product="CpsIaD"
                     /protein_id="AAL57052.1"
                     /transl_table=11
                     /translation="MKEQMEQSGSKFLGIILNKVSESVATYGDYGDYGNYGKRDRKRK"
     source          1..4888
                     /db_xref="taxon:1311"
                     /mol_type="genomic DNA"
                     /organism="Streptococcus agalactiae"
                     /serotype="Ia"
                     /strain="090"
     subregion       1..4888
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000740"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..4888
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            361..1536
                     /gene="cpsIaE"
     CDS             361..1536
                     /codon_start=1
                     /gene="cpsIaE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 332.3; E-value:
                     8.3e-101)"
                     /gene_kind="biosynthetic-additional"
                     /product="CpsIaE"
                     /protein_id="AAL57053.1"
                     /sec_met_domain="Bac_transf (E-value: 2.6e-70, bitscore:
                     224.5, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLKYSFYYIFISSSLFFIFKNSFTTTRLSFFSFIAMNSILLYLL
                     NSFLKYYRKYSYAKFSRDTKVVLITNKDSLSKMTFRNKYDHNYIAVCILDSSEKDCYDL
                     KHNSLRIINKDALTSELTCLTVDQAFINIPIELFGKYQIQDIINDIEAMGVIVNVNVEA
                     LSFDNIGEKRIQTFEGYSVITYSMKFYKYSHLIAKRFLDITGAIIGLLICGIVAIFLVP
                     QIRKDGGPAIFSQNRVGRNGRIFRFYKFRSMRVDAEQIKKDLLVHNQMTGLMFKLDDDP
                     RITKIGKFIRKTSIDELPQFYNVLKGDMSLVGTRPPTVDEYEKYNSTQKRRLSFKPGIT
                     GLWQISGRNNITDFDEIVKLDVQYINEWSIWSDIKIILLTLKVVLLGTGAK"
     gene            1560..2009
                     /gene="cpsIaF"
     CDS             1560..2009
                     /codon_start=1
                     /gene="cpsIaF"
                     /product="CpsIaF"
                     /protein_id="AAL57054.1"
                     /transl_table=11
                     /translation="MKICLVGSSGGHLAHLNLLKPIWEKEDRFWVTFDKEDARSILREE
                     IVYHCFFPTNRNVKNLVKNTILAFKVLRKERPDVIISSGAAVAVPFFYIGKLFGCKTVY
                     IEVFDRIDKPTLTGKLVYPVTDKFIVQWEEMKKVYPKAINLGGIF"
     gene            2009..2491
                     /gene="cpsIaG"
     CDS             2009..2491
                     /codon_start=1
                     /gene="cpsIaG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /product="CpsIaG"
                     /protein_id="AAL57055.1"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 2.3e-48,
                     bitscore: 153.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFVTVGTHEQQFNRLIKEVDRLKGTGAIDQEVFIQTGYSDFEPQ
                     NCQWSKFLSYDDMNSYMKEAEIVITHGGPATFMNAVSKGKKTIVVPRQEQFGEHVNNHQ
                     VDFLKELFLKYELDYILNISELENIIKEKNISTSKVISQNNDFCSSFKNELSKLFE"
     gene            2587..3726
                     /gene="cpsIaH"
     CDS             2587..3726
                     /codon_start=1
                     /gene="cpsIaH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /product="CpsIaH"
                     /protein_id="AAL57056.1"
                     /sec_met_domain="Wzy_C (E-value: 2.2e-11, bitscore: 33.0,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQLLLLLALIVLLICSSYNEKMKFLNMAEIFFIVFYIIYLTSILL
                     HSLFKNPDFDRILAAFNSLIIGIVSLAFYHYYKNTTLELDKILKAFLFNGLILFFLGGT
                     YYYCLHNNIQNISIFGRDLIGSDWINGMHTQRAMGFFEYSNLIIPITVVTNLYIYIYMK
                     LRNYSIMTIGVVLLFTFILPIGSGSRAGIVAILAQMFILLLNTVVVKKKTIKFLLYILP
                     FLLVIVMMLYFDNLLSIYYRIINLRSGSSESRFSLYKDTVNIVINNSLLFGEGVKELWL
                     NSDLPLGSHSTYIGYFYKSGLLGLMNIVPGLLLIFTNIGRKAKQSAFYYEIVGTLITLF
                     SFFALEDLDGANWLIVFIFTVLGILENKDFYSQLKRWKS"
     gene            3726..4700
                     /gene="cpsIaI"
     CDS             3726..4700
                     /codon_start=1
                     /gene="cpsIaI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 63; E-value: 5.5e-19)"
                     /gene_kind="biosynthetic-additional"
                     /product="CpsIaI"
                     /protein_id="AAL57057.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.3e-44,
                     bitscore: 140.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKRILVSIIIPIYNSEAYLKECVQSVLQQTHPLIEVILIDDGST
                     DNSGEICDNLSQEDNRILVFHKKNGGVSSARNLGLDKSTGEFITFVDSDDFVAPNMIEI
                     MLKNLITENADIAEVDFDISNERDYRKKKRRNFYKVFKNNNSLKEFLSGNRVENIVCTK
                     LYKKSIIGNLRFDENLKIGEDLLFNCKLLCQEHRIVVDTTSSLYTYRIVKTSAMNQKFN
                     ENSLDFITIFNEVSSLVPAKLANYVEAKFLREKIKCLRKMFELGSNIDNKIKVQREIFF
                     KDIKSYPFYKAVKYLSLKGLLSFYLMKCSPKLYVMAYRRFQKQ"
     gene            4734..>4888
                     /gene="cpsIaJ"
     CDS             4734..>4888
                     /codon_start=1
                     /gene="cpsIaJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /product="CpsIaJ"
                     /protein_id="AAL57058.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.7e-18,
                     bitscore: 53.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKIEKDLISVIVPIYNVEDYLVECIESLIVQTYRNIEILLIND
                     GSTDNCA"
ORIGIN
        1 gcaaaagaac agatggaaca aagtggttca aagttcttag gtattattct taataaagtt
       61 agtgaatctg ttgctactta cggcgattac ggcgattatg gaaattacgg aaaaagggat
      121 agaaaaagga agtaaggggc tcttgtattg aaagaaaaag aaaatataca aaagattatt
      181 atagcgatga ttcaaacagt tgtggtttat ttttctgcaa gtttgacatt aacattaatt
      241 actcccaatt ttaaaagcaa taaagattta ttgtttgttc tattgataca ttatattgtc
      301 ttttatcttt ctgattttta cagagacttt tggagtcgtg gctatcttga agagtttaaa
      361 atggtattga aatacagctt ttactatatt ttcatatcaa gttcattatt ttttattttt
      421 aaaaactcat ttacaacgac acgactttcc tttttttctt ttattgctat gaattcgatt
      481 ttattgtatc tattgaattc atttttaaaa tattatcgaa aatattctta cgctaagttt
      541 tcacgagata ccaaagttgt tttgataacg aataaggatt ctttatcaaa aatgaccttt
      601 aggaataaat acgaccataa ttatattgct gtctgcatct tggactcctc tgaaaaggat
      661 tgttatgatt tgaaacataa ctcgttaagg ataataaaca aagatgctct tacttcagag
      721 ttaacctgct taactgttga tcaagctttt attaacatac ccattgaatt atttggtaaa
      781 taccaaatac aagatattat taatgacatt gaagcaatgg gagtgattgt caatgttaat
      841 gtagaggcac ttagctttga taatatagga gaaaagcgaa tccaaacttt tgaaggatat
      901 agtgttatta catattctat gaaattctat aaatatagtc accttatagc aaaacgattt
      961 ttggatatca cgggtgctat tataggtttg ctcatatgtg gcattgtggc aatttttcta
     1021 gttccacaaa tcagaaaaga tggtggaccg gctatctttt ctcaaaatag agtaggtcgt
     1081 aatggtagga tttttagatt ctataaattc agatcaatgc gagtagatgc agaacaaatt
     1141 aagaaagatt tattagttca caatcaaatg acagggctaa tgtttaagtt agacgatgat
     1201 cctagaatta ctaaaatagg aaaatttatt cgaaaaacaa gcatagatga gttgcctcaa
     1261 ttctataatg ttttaaaagg tgatatgagt ttagtaggaa cacgccctcc cacagttgat
     1321 gaatatgaaa agtataattc aacgcagaag cgacgcctta gttttaagcc aggaatcact
     1381 ggtttgtggc aaatatctgg tagaaataat atcactgatt ttgatgaaat cgtaaagtta
     1441 gatgttcaat atatcaatga atggtctatt tggtcagata ttaagattat tctcctaaca
     1501 ctaaaggtag tcttacttgg gacaggtgct aagtaaaggt aaggtttgaa aggaatataa
     1561 tgaaaatttg tctggttggt tcaagtggtg gtcatctagc acacttgaac cttttgaaac
     1621 ccatttggga aaaagaagat aggttttggg taacctttga taaagaagat gctaggagta
     1681 ttctaagaga agagattgta tatcattgct tctttccaac aaaccgtaat gtcaaaaact
     1741 tggtaaaaaa tactattcta gcttttaagg tccttagaaa agaaagacca gatgttatca
     1801 tatcatctgg tgccgctgta gcagtaccat tcttttatat tggtaagtta tttggttgta
     1861 agaccgttta tatagaggtt ttcgacagga tagataaacc aactttgaca ggaaaattag
     1921 tgtatcctgt aacagataaa tttattgttc agtgggaaga aatgaaaaaa gtttatccta
     1981 aggcaattaa tttaggagga attttttaat gatttttgtc acagtgggga cacatgaaca
     2041 gcagttcaac cgtcttatta aagaagttga tagattaaaa gggacaggtg ctattgatca
     2101 agaagtgttc attcaaacgg gttactcaga ctttgaacct cagaattgtc agtggtcaaa
     2161 atttctctca tatgatgata tgaactctta catgaaagaa gctgagattg ttatcacaca
     2221 tggcggtcca gcgacgttta tgaatgcagt ttctaaaggg aaaaaaacta ttgtggttcc
     2281 tagacaagaa cagtttggag agcatgtgaa taatcatcag gtggattttt tgaaagagtt
     2341 attcttgaaa tatgaattag attatatttt gaatatcagt gaattagaga atattattaa
     2401 ggaaaaaaat atatctacta gtaaagtaat atcacaaaac aatgattttt gttcctcttt
     2461 caaaaatgaa ctttctaaac tatttgaata aatatatttt gttggagaaa aaaattgaaa
     2521 ttaactatca atccaaagta tttgttaata ggaggaattt tcgctttaac cctattttca
     2581 aagccaatgc aacttttgtt acttttagca ttaatagttt tacttatttg tagtagttat
     2641 aatgaaaaaa tgaaattttt aaatatggct gaaatttttt tcattgtatt ttatattatt
     2701 tatttaactt caatattgct acattctttg tttaaaaatc ctgattttga tagaatttta
     2761 gcagctttta actcgttgat tatcggtata gtatcattgg ctttttatca ttattataag
     2821 aatacaactt tggagttaga taaaatatta aaagcatttt tatttaatgg gttaatccta
     2881 ttttttttag ggggaacata ttattattgt ttgcataata atattcaaaa tatcagtatt
     2941 tttggtagag atttgattgg gtcagactgg attaatggta tgcatactca aagagcaatg
     3001 ggattttttg aatattcaaa ccttataatt cctattacag tggtaactaa cttatatata
     3061 tatatatata tgaagttaag aaactattca attatgacca taggtgttgt attattattt
     3121 acctttattt tacctattgg atcgggctcc agggctggaa tagtagctat attggcgcag
     3181 atgtttattc ttcttctaaa tacagttgtc gtaaagaaga aaactataaa atttttattg
     3241 tacatacttc cgtttctact agtaatagta atgatgttat attttgataa cttactatct
     3301 atatattatc gtataattaa tttgcgatcc gggagtagtg aatccagatt ttctttatat
     3361 aaagatacag taaacatcgt tataaataat tctttattat ttggagaagg agttaaagag
     3421 ttatggttaa atagtgatct ccctttgggg tcgcattcaa cgtatatagg ctatttctac
     3481 aaaagtggcc tgctgggatt aatgaatata gttccaggtt tgcttttaat ttttactaat
     3541 attggtagga aagctaaaca atcagctttt tattatgaga tagtaggaac acttataact
     3601 ttattctcat tttttgcact tgaagatctt gacggagcta attggcttat tgtttttatt
     3661 tttacagtgt taggaatttt agaaaataag gatttttata gtcaacttaa aaggtggaaa
     3721 agttaatgga aaaacgaata cttgtttcta tcattatacc tatatacaac tcagaagcat
     3781 accttaaaga atgtgtgcaa tccgtactac aacagactca tccattgata gaagttatac
     3841 taattgatga tggatccact gataatagtg gagaaatttg tgataattta tctcaagaag
     3901 ataatcgcat acttgtattt cataaaaaaa atggaggggt ctcttcggca aggaacctag
     3961 gtctagataa atccacagga gaattcataa catttgtgga tagtgatgat tttgtagcac
     4021 cgaatatgat tgaaataatg ttaaaaaatt taatcactga gaatgctgat atagcagaag
     4081 tagattttga tatttcgaat gagagagatt atagaaagaa gaaaagacga aacttttata
     4141 aagtctttaa aaacaataac tctttaaaag aatttttatc aggcaataga gtggaaaata
     4201 ttgtttgtac aaaattatat aaaaaaagta taattggcaa cttgaggttt gatgagaact
     4261 taaaaattgg tgaggattta ctttttaatt gtaaactctt atgtcaagag caccgtatag
     4321 tcgtagatac gacttcttcc ttatatactt atcgaattgt aaaaacttcc gcaatgaatc
     4381 agaaattcaa cgaaaactca ttagatttta taacaatttt taatgaagta agtagtttgg
     4441 ttcctgccaa attggctaat tatgttgaag cgaaattttt aagagaaaag ataaagtgtc
     4501 tccgaaaaat gtttgaatta ggtagtaata ttgacaataa aatcaaagta caacgagaga
     4561 tttttttcaa agacattaaa tcatacccgt tctataaagc ggtaaaatac ttatcattaa
     4621 agggattatt aagcttttat ttaatgaaat gttcacctaa actatatgtt atggcatata
     4681 gaagatttca aaaacagtag ctggagaaat tgggaaagag aatttataac ttcatgataa
     4741 agaaaattga aaaggattta ataagtgtaa ttgtacctat ttataatgtt gaagattatt
     4801 tagttgaatg tatagaaagc cttattgttc aaacatatcg aaatattgaa atattattga
     4861 ttaatgatgg ttcgacggat aattgtgc
//
