LOCUS       BGC0000741              4768 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Streptococcus agalactiae strain M781 capsular polysaccharide
            biosynthesis gene cluster, partial sequence.
ACCESSION   BGC0000741
VERSION     BGC0000741
KEYWORDS    .
SOURCE      Streptococcus agalactiae
  ORGANISM  Streptococcus agalactiae
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 20:27:21
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 4768
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..126
                     /gene="cpsD"
     CDS             <1..126
                     /codon_start=1
                     /gene="cpsD"
                     /product="CpsD"
                     /protein_id="AAL57071.1"
                     /transl_table=11
                     /translation="AKEQMEQSGSKFLGIILNKVNESVATYGDYGNYGKRDRKRK"
     source          1..4768
                     /db_xref="taxon:1311"
                     /mol_type="genomic DNA"
                     /organism="Streptococcus agalactiae"
                     /serotype="III"
                     /strain="M781"
     subregion       1..4768
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Saccharide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..4768
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            178..1527
                     /gene="cpsE"
     CDS             178..1527
                     /codon_start=1
                     /gene="cpsE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 338.1; E-value:
                     1.4e-102)"
                     /gene_kind="biosynthetic-additional"
                     /product="CpsE"
                     /protein_id="AAL57072.1"
                     /sec_met_domain="Bac_transf (E-value: 2.6e-70, bitscore:
                     224.5, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIQTVVVYFSASLTLTLITPNFKSNKDLLFVLLIHYIVFYLSDFY
                     RDFWSRGYLEEFKMVLKYSFYYIFISSSLFFIFKNSFTTTRLSFFTFIAMNSILLYLLN
                     SFLKYYRKYSYAKFSRDTKVVLITNKDSLSKMTFRNKYDHNYIAVCILDSSEKDCYDLK
                     HNSLRIINKDALTSELTCLTVDQAFINIPIELFGKYQIQDIINDIEAMGVIVNVNVEAL
                     SFDNIGEKRIQTFEGYSVITYSMKFYKYSHLIAKRFLDITGAIIGLLICGIVAIFLVPQ
                     IRKDGGPAIFSQNRVGRNGRIFRFYKFRSMRVDAEQIKKDLLVHNQMTGLMFKLEDDPR
                     ITKIGKFIRKTSIDELPQFYNVLKGDMSLVGTRPPTVDEYEKYNSTQKRRLSFKPGITG
                     LWQISGRNNITDFDEIVKLDVQYINEWSIWSDIKIILLTLKVVLLGTGAK"
     gene            1551..2000
                     /gene="cpsF"
     CDS             1551..2000
                     /codon_start=1
                     /gene="cpsF"
                     /product="CpsF"
                     /protein_id="AAL57073.1"
                     /transl_table=11
                     /translation="MKICLVGSSGGHLAHLNLLKPIWEKEDRFWVTFDKEDARSILREE
                     IVYHCFFPTNRNVKNLVKNTILAFKVLRKERPDVIISSGAAVAVPFFYIGKLFGCKTVY
                     IEVFDRIDKPTLTGKLVYPVTDKFIVQWEEMKKVYPKAINLGGIF"
     gene            2000..2473
                     /gene="cpsG"
     CDS             2000..2473
                     /codon_start=1
                     /gene="cpsG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /product="CpsG"
                     /protein_id="AAL57074.1"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 1.1e-45,
                     bitscore: 144.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFVTVGTHEQQFNRLIKEVDRLKGTGAIDQEVFIQTGYSDFEPQ
                     NCQWSKFLSYDDMNSYMKEAEIVITHGGPATFMSVISLGKLPVVVPRRKQFGEHINDHQ
                     IQFLKKIAHLYPLAWIEDVDGLAEALKRNIATEKYQGNNDMFCHKLEKIIGEI"
     gene            2470..3615
                     /gene="cpsIaH"
     CDS             2470..3615
                     /codon_start=1
                     /gene="cpsIaH"
                     /product="CpsIaH"
                     /protein_id="AAL57075.1"
                     /transl_table=11
                     /translation="MRKYLDLDYSLFYALWVLILVPNQWYQFLIITIIVLLLLWKSEFR
                     ISISNSSILFLLWLFIYLFAILIRGTQEDITFQRFIAELLKLISTGYALFFYNYYRKAD
                     FNSSVVRNVVKVNYFVLFLITVLYLFFPMLKPTLFGRELFSIEWFPHMRIRLAAYFEYA
                     TLIGQFILFSYPILFLKPQKHMENILISLLLTICSYFSGARILLVCMLVLLASLLLDYI
                     LFKTNLKLTKKNTFILGMTFLFITACFSYNIWSIIEKIIMYRNQSTITRMIVYQESIIE
                     VLKGNILFGQGIRIPSSEGIFLGSHSTYISVFYRTSLLGIVLYFSAFILLYKEAISKNY
                     KIYRLFFYTLLCYTLFEEIDPNHWSIVLLFSTFGIVGRAKK"
     gene            3612..4580
                     /gene="cpsI"
     CDS             3612..4580
                     /codon_start=1
                     /gene="cpsI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 62.8; E-value: 6.2e-19)"
                     /gene_kind="biosynthetic-additional"
                     /product="CpsI"
                     /protein_id="AAL57076.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.1e-44,
                     bitscore: 138.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEKVTVIIPIYNSEAYLKECVQSVLQQTHPLIEVILIDDGSTDN
                     SGEICDNLSQEDNRILVFHKKNGGVSSARNLGLDKSTGEFITFVDSDDFVAPNMIEIML
                     KNLITENADIAEVDFDISNERDYRKKKRRNFYKVFKNNNSLKEFLSGNRVENIVCTKLY
                     KKSIIGNLRFDENLKIGEDLLFNCKLLCQEHRIVVDTTSSLYTYRIVKTSVMNQKFNEN
                     SLDFITIFNEISSLVPARLANYVEAKFLREKIKCLRKMFELGSNIDNKIKVQREIFFKD
                     IKSYPFYKAVKYLSLKGLLSFYLMKCSPKLYVMAYRRFQKQ"
     gene            4614..>4768
                     /gene="cpsJ"
     CDS             4614..>4768
                     /codon_start=1
                     /gene="cpsJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /product="CpsJ"
                     /protein_id="AAL57077.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.7e-18,
                     bitscore: 53.7, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKKIEKDLISVIVPIYNVEDYLVECIESLIVQTYRNIEILLIND
                     GSTDNCA"
ORIGIN
        1 gcaaaagaac agatggaaca aagtggttca aagttcttag gtattattct taataaagtt
       61 aatgaatctg ttgctactta cggcgattat ggaaattacg gaaaaaggga tagaaaaagg
      121 aagtaaggga ctctggtatt gaaagaaaaa gaaaatatac aaaagattat tatagcgatg
      181 attcaaacag ttgtagttta tttttctgca agtttgacat taacattaat tactcccaat
      241 tttaaaagca ataaagattt attgtttgtt ctattgatac attatattgt tttttatctt
      301 tctgattttt acagagactt ttggagtcgt ggctatcttg aagagtttaa aatggtattg
      361 aaatacagct tttactatat tttcatatca agttcattat tttttatttt taaaaactct
      421 tttacaacga cacgactttc cttttttact tttattgcta tgaattcgat tttattatat
      481 ctattgaatt catttttaaa atattatcga aaatattctt acgctaagtt ttcacgagat
      541 accaaagttg ttttgataac gaataaggat tctttatcaa aaatgacctt taggaataaa
      601 tacgaccata attatatcgc tgtctgtatc ttggactcct ctgaaaagga ttgttatgat
      661 ttgaaacata actcgttaag gataataaac aaagatgctc ttacttcaga gttaacctgc
      721 ttaactgttg atcaagcttt tattaacata cccattgaat tatttggtaa ataccaaata
      781 caagatatta ttaatgacat tgaagcaatg ggagtgattg tcaatgttaa tgtagaggca
      841 cttagctttg ataatatagg agaaaagcga atccaaactt ttgaaggata tagtgttatt
      901 acatattcta tgaaattcta taaatatagt caccttatag caaaacgatt tttggatatc
      961 acgggtgcta ttataggttt gctcatatgt ggcattgtgg caatttttct agttccgcaa
     1021 atcagaaaag atggtggacc ggctatcttt tctcaaaata gagtaggtcg taatggtagg
     1081 atttttagat tctataaatt cagatcaatg cgagtagatg cagaacaaat taagaaagat
     1141 ttattagttc acaatcaaat gacagggcta atgtttaagt tagaagatga tcctagaatt
     1201 actaaaatag gaaaatttat tcgaaaaaca agcatagatg agttgcctca attctataat
     1261 gttttaaaag gtgatatgag tttagtagga acacgccctc ccacagttga tgaatatgaa
     1321 aagtataatt caacgcagaa gcgacgcctt agttttaagc caggaatcac tggtttgtgg
     1381 caaatatctg gtagaaataa tattactgat tttgatgaaa tcgtaaagtt agatgttcaa
     1441 tatatcaatg aatggtctat ttggtcagat attaagatta ttctcctaac actaaaggta
     1501 gttttactcg ggacaggagc taagtaaagg taaggtttga aaggaatata atgaaaattt
     1561 gtctggttgg ttcaagtggt ggtcatctag cacacttgaa ccttttgaaa cccatttggg
     1621 aaaaagaaga taggttttgg gtaacctttg ataaagaaga tgctaggagt attctaagag
     1681 aagagattgt atatcattgc ttctttccaa caaaccgtaa tgtcaaaaac ttggtaaaaa
     1741 atactattct agcttttaag gtccttagaa aagaaagacc agatgttatc atatcatctg
     1801 gtgccgctgt agcagtacca ttcttttata ttggtaagtt atttggttgt aagaccgttt
     1861 atatagaggt tttcgacagg atagataaac caactttgac aggaaaatta gtgtatcctg
     1921 taacagataa atttattgtt cagtgggaag aaatgaaaaa agtttatcct aaggcaatta
     1981 atttaggagg aattttttaa tgatttttgt cacagtgggg acacatgaac agcagttcaa
     2041 ccgtcttatt aaagaagttg atagattaaa agggacaggt gctattgatc aagaagtgtt
     2101 cattcaaacg ggttactcag acttcgaacc tcagaattgt cagtggtcaa aatttctctc
     2161 atatgatgat atgaactctt acatgaaaga agctgagatt gttatcacac atggcggccc
     2221 agcgacgttt atgtcagtta tttctttagg gaaattacca gttgttgttc ctaggagaaa
     2281 gcagtttggt gaacatatca atgatcatca aatacaattt ttaaaaaaaa ttgcccacct
     2341 gtatcccttg gcttggattg aagatgtaga tggacttgcg gaagcgttga aaaggaatat
     2401 agctacagaa aaatatcagg gaaataatga tatgttttgt cataaattag aaaaaattat
     2461 aggtgaaata tgaggaaata tctagattta gattattctt tattttatgc tctttgggta
     2521 cttattttag taccaaacca atggtatcag tttttaatta ttaccattat agttctatta
     2581 ttactttgga agagtgagtt tagaatatct ataagcaatt cttcaatact atttctgctt
     2641 tggttattta tttatttatt tgcaatactc attagaggta ctcaagagga tataacgttt
     2701 cagcgattta ttgctgagct attaaaacta attagtacag gatatgcttt atttttttat
     2761 aattattata gaaaagctga ttttaatagt tcagttgtaa ggaatgtggt aaaggttaac
     2821 tattttgtgt tgtttcttat aacagtttta tatttatttt ttcctatgct gaagccaact
     2881 ttatttggaa gagaattgtt ttcaatagag tggtttccac atatgagaat aagacttgcg
     2941 gcatattttg aatatgctac actaattggt cagtttattt tattttctta tcccatactt
     3001 tttttgaaac cccaaaaaca tatggaaaat attttaatat ccttactgtt gactatatgt
     3061 tcatactttt ctggcgctag aatactattg gtctgtatgt tggttttatt agcttcgctt
     3121 cttttagatt atatcctttt taaaactaat ttgaaattga ccaagaaaaa cacttttata
     3181 cttggtatga ctttcttatt tatcaccgct tgtttttctt ataacatatg gtcaataatt
     3241 gaaaaaataa ttatgtacag aaaccaaagt actatcacta ggatgatagt ttatcaagaa
     3301 agtattattg aagttctaaa aggaaatatt ttatttggac agggtataag gattccatca
     3361 agtgaaggaa tattcctagg atcgcattct acttatatta gtgtctttta caggacttct
     3421 ttattaggaa ttgttcttta tttttctgcc tttatacttt tatataaaga agcgatttca
     3481 aaaaattata aaatctacag attatttttt tatacgttat tatgttacac gctctttgag
     3541 gaaatagatc ctaatcattg gagtattgta ttattattct caacttttgg tatagtggga
     3601 agggctaaaa aatgaaagaa aaagtaacag tcattatacc tatatacaac tcagaagcat
     3661 accttaaaga atgtgtgcaa tccgtactac aacagactca tccattgata gaagttatac
     3721 taattgatga tggatccact gataatagtg gagaaatttg tgataattta tctcaggaag
     3781 ataatcgcat acttgtattt cataaaaaaa atggaggggt ctcttcggca aggaacctag
     3841 gtctagataa atccacagga gaattcataa catttgtgga tagtgatgat tttgtagcac
     3901 cgaatatgat tgaaataatg ttaaaaaatt taatcactga gaatgctgat atagcagaag
     3961 tagattttga tatttcgaat gagagagatt atagaaagaa gaaaagacga aacttttata
     4021 aagtttttaa gaataataac tctttgaaag aatttttatc aggtaataga gtggaaaata
     4081 ttgtttgtac aaaattatat aaaaaaagta taattggtaa cttgaggttt gatgagaact
     4141 taaaaattgg tgaggattta ctttttaatt gcaaactctt atgtcaagag caccgtatag
     4201 tcgtagatac gacttcttcc ttatatactt atcgaattgt aaaaacttct gtaatgaatc
     4261 agaaattcaa cgaaaactca ttagatttta taacaatttt taatgaaata agtagtttgg
     4321 ttcctgccag attagctaat tatgttgaag cgaaattttt aagagaaaag ataaagtgtc
     4381 tccgaaaaat gtttgaatta ggtagtaata ttgacaataa aatcaaagta caacgagaga
     4441 tttttttcaa agacattaaa tcatacccgt tctataaagc ggtcaaatac ttatcattaa
     4501 agggattatt aagcttttat ttaatgaaat gttcacctaa actatatgtt atggcatata
     4561 gaagatttca aaaacagtag ctggagaaat ttggaaagag aatttataac ttcatgataa
     4621 agaaaattga aaaggattta ataagtgtaa ttgtacctat ttataatgtt gaagattatt
     4681 tagttgaatg tatagaaagc cttattgttc aaacatatcg aaatattgaa atattattga
     4741 ttaatgatgg ttcgacggat aattgtgc
//
