LOCUS       BGC0000759             29473 bp    DNA     linear   BCT 26-JUL-2016
DEFINITION  Sphingomonas sp. ATCC 53159 diutan polysaccharide synthesis gene
            cluster, partial sequence.
ACCESSION   BGC0000759
VERSION     BGC0000759
KEYWORDS    .
SOURCE      Sphingomonas sp. ATCC 53159
  ORGANISM  Sphingomonas sp. ATCC 53159
            Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
            Sphingomonadaceae; Sphingomonas.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 14:09:41
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 29473
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..>1054
                     /gene="dpsS"
     source          1..29473
                     /db_xref="ATCC:53159"
                     /db_xref="taxon:194870"
                     /mol_type="genomic DNA"
                     /organism="Sphingomonas sp. ATCC 53159"
                     /strain="ATCC 53159"
     misc_feature    <1..29473
                     /note="diutan polysaccharide synthesis gene cluster"
     subregion       1..29473
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="saccharide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..29473
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             <1..1054
                     /codon_start=2
                     /gene="dpsS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /product="putative repeat unit transporter"
                     /protein_id="ABW74878.1"
                     /sec_met_domain="Polysacc_synt (E-value: 3.3e-16, bitscore:
                     50.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGALLGRHKFVLVNVSTVASSILFQLFPLVVAWMIGPDLRTLLI
                     AALVGRAVPMIGMLPALYRNLLRGNTPRFHASEARFLIGYGGWASLTTVVATVLMMADR
                     FLIGALLGPVAVTIYTAPLQLAQRVSLLPSALSAALFPRLPSATPAERMALQIRSLSLI
                     MGGLTGMIGGGLLLAAPFLDLWIGKSLGHAGTPVALFLFFGAWWNALAIISFSGLQASG
                     RPKASAIVQGAELLPVLIALYAGIRWGGVTGAAAVFLGRSALDFVLLTWQAGLLRQTVK
                     QVSVCGAVLTVAMLVGATYRYSVPLWCVLSACCLVALAACSWWTLARQDKALLIGRLSR
                     ILPKQRQLDL"
     gene            complement(1113..2738)
                     /gene="dpsG"
     CDS             complement(1113..2738)
                     /codon_start=1
                     /gene="dpsG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /product="putative diutan polysaccharide polymerase"
                     /protein_id="ABW74879.1"
                     /sec_met_domain="Wzy_C (E-value: 6.5e-15, bitscore: 46.2,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTSAFRRPAFHGAMQRLRRLRLVRFLTKPAIPVLPVYKAERSG
                     VTIAARRTVLLVSVMFLAAVYGLLAAVLPLQMLAIPAVPLVLMALVVIWALPEARQAPT
                     RLLAKLYLAYMVAALVWPNYLALSVGGLPWISIRRMIGSIALLTLMISLSVSKKFRSEM
                     AAIMRAAPIPSRLLLAFIMVQIVASIATPAASQTIPRLIGIVLTVTPMAFISLWLIGTD
                     TRTPEWWVTRLFWCVGVLMAIGVLEFRVKHVLWAYSIPSFLRVDEQFLTVVLTPGFRGT
                     YRVLTTFSSPLVWGELTALTIPFVLHRIANSRGVGRLAFWIFFDFLVVASGFLSGSRLA
                     MVGGLVAHTVYLLIWAIRRWRTTKGGLVGISLTLTYPALMVALSLAVMFVPAVHNRVLG
                     GGASQLSNQGRQEQFRLGVPAIARRPFFGYGPGEGAGAVGWRNQQGFLSIDSGFLSVAA
                     DYGLLGFVSLYGTMITLMILLAFRGLKMSGDGYPLELAVATFLAVLLNTRSVLSQGDND
                     PFIFMTLGLGIALLYRSRPVSLSV"
     gene            complement(2898..4895)
                     /gene="dpsR"
     CDS             complement(2898..4895)
                     /codon_start=1
                     /gene="dpsR"
                     /product="putative diutan polysaccharide lyase"
                     /protein_id="ABW74880.1"
                     /transl_table=11
                     /translation="MPDIIVKNQTELNAAIAAAKGGETIKLAAGVYTDLTVMTKTFTSM
                     VTIESLDSSNPVNIQKLVIGNSSNVTVKNMVAATDYKPADDWNRLNTIQGSANIVLDGV
                     RFSGGTGDPSLSKGAGLFVRNSTSVTMQNSSIDHFGLGLEAYNVDGMVVQNSSFHDNRR
                     DHTNFTEMNNLVIDGNSFTNLFPVGTEHPDAIQFFTAGKVKGNTNITISNNVIMQGAGS
                     GAQGIFMNDEAGNLPYVNVNIKNNLIYLNGYYHGINVVNGVNVNIESNSVISQVDGTSF
                     WIRLDKTNGATIKNNVADLITVTSSSSNIVQTGNRTLTSDSATIRKIYGLNDGATARLS
                     DLIVPGVGYQPPVSSAAAAQVTTELSTAKAANPSLLLDLSFSNSGVVDLSHWNTGQTTK
                     AVDVSAVVGSAFHVSTGTGVELNRSYSRQIYALSAFTLSFDLKRDSATATAGQILGIFQ
                     SWSVSLQANGELSFTMRNAAGVSQTMVTSGAKLLDAATHKIALTYDSTRKTAILYVDGM
                     QRGTATMTGTTRPAESWGLYVGSPFSTAFSGTVGDIEIRDGAISAAQVQALVTASSASA
                     AATVKDSLVTGAAAQAAALLAGAGAASTATPLATVATVGSTLSIGTAASSQIALVSKIG
                     VDMMTAGAMGAIRSAATLSATADQYNLYRA"
     gene            5093..6031
                     /gene="dpsQ"
     CDS             5093..6031
                     /codon_start=1
                     /gene="dpsQ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /product="rhamnosyl transferase"
                     /protein_id="ABW74881.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.1e-21,
                     bitscore: 68.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQMLPTPDVSILVVAFNSTEYIEDCLRGIAEGAGKTPHEVLLIDN
                     GDGRTEALVRQRFHHVRIVPSEGNIGFGAGNNRLAAQAAGPLLLLVNPDAIPQPGAIDQ
                     LVTFAKQHPEAAAWGGRSYSPSGDLEPANFMSLPTPADFLTAIFNARALRSGGLQEGAT
                     TPGAVEVLNGGFMMVRTDVWQAIGGFDESFFLYSEEIDLFQRIRTLGHKVLVDPSVKVV
                     HNTGSGQSMSQNRLMYLTTGRMHYARKHFGALGTLATGCALWLIAAKYTLVGAALWRLS
                     PRTGTRYKELSNGWRAVFSNPGRWWSGYPRR"
     gene            complement(6111..6983)
                     /gene="dpsI"
     CDS             complement(6111..6983)
                     /codon_start=1
                     /gene="dpsI"
                     /product="conserved hypothetical protein"
                     /protein_id="ABW74882.1"
                     /transl_table=11
                     /translation="MKKLYLVTAVAAAALAVSGCGGKGGKLDKGQVVASVDGEEITVFE
                     LNAELQASQVPPGTDRKLAEQLALQRIIERKILAKVAREQKLDKTPAFLIQERRADELI
                     LTAMLRDKIAGGIAQPTDAEIEKYQAAHPERFAQRKIYAIDQVVFAPPSSAAKLKQFAP
                     LKTLDQLTAKLSADNVQFRRAPSQIDTAALPPEIAAKIASLPAQEMFILPTQQGLTANI
                     ITSTTVLPVPADQAREIALSGLRTERFGKAADAQLNDRLKKARETVKYQAGYSAPPQLR
                     GSGATPAGN"
     gene            7121..8167
                     /gene="dpsK"
     CDS             7121..8167
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (313-347). E-value:
                     0.00046. Score: 12.9. Matches aSDomain:
                     nrpspksdomains_dpsK_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene="dpsK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /product="beta-1,4-glucuronosyl transferase"
                     /protein_id="ABW74883.1"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 5.4e-35,
                     bitscore: 111.4, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEANAVDGKASKPLKMCLAASGGGHLRQILDLESVWREHDYFFV
                     TEDTALGRSLAEKHPVELVEHYALGQAKLGHPLRMLGGAWRNLRQSLSILRRHKPDVVI
                     STGAGAVYFTALLAKLSGAKFVHIESFARFDHPSAFGKMVKGIATVTIVQSAALKETWP
                     DAELFDPFRLLDTPRPPKQALIFATVGATLPFPRLVQAVLDLKRAGGLPGKLILQYGDQ
                     DLPDPGIPDVEIRRTIPFDDLQLLLRDADMVICHGGTGSLVTALRAGCRVVAFPRRHDL
                     GEHYDDHQEEIAQTFADRGLLQAVRDERQLGAAVEAAKATEPQLATTDHTALAARLRQL
                     LAQWSAKR"
     aSDomain        8060..8161
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_dpsK_PKS_Docking_Cterm.1"
                     /evalue="4.60E-04"
                     /label="dpsK_PKS_Docking_Cterm.1"
                     /locus_tag="dpsK"
                     /protein_end="347"
                     /protein_start="313"
                     /score="12.9"
                     /tool="antismash"
                     /translation="AVEAAKATEPQLATTDHTALAARLRQLLAQWSAK"
     gene            8164..9030
                     /gene="dpsL"
     CDS             8164..9030
                     /codon_start=1
                     /gene="dpsL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /product="glucosyl transferase"
                     /protein_id="ABW74884.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.1e-22,
                     bitscore: 69.9, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPRISVVIPHYNDPQSLRLCLDALERQTIGRDAFEIIVGDNNS
                     PCGLAAVEAAVAGRARIVTILEKGAGPARNGAAAAARGEILAFTDSDCVVEPGWLAGGT
                     TRVAPGRFIGGHMYVRKPEGPPNGAEALEMALAFDNEGYVRRTQFTVTANLFVMRADFE
                     RVGGFRVGVSEDLEWCHRAIASGLTINYAPDASVGHPPRPDWSALLVKTRRIQRELYLF
                     NIERPKGRLRWLVRSVAQPAMIPQDVAKILRTPGTKGARLAAVTTLVRLRLWRGGAGLL
                     QLLGRDI"
     gene            complement(9079..10467)
                     /gene="dpsJ"
     CDS             complement(9079..10467)
                     /codon_start=1
                     /gene="dpsJ"
                     /product="conserved hypothetical protein"
                     /protein_id="ABW74885.1"
                     /transl_table=11
                     /translation="MAVGSALRFLWPFGRREEPEEEGYFPLTATVVPHRDAHSGRGRPD
                     FPTFRASALDRPLDRRRDERREITRARFALATFFTPTQPVADRSSFAGRLGVLARLISS
                     IESQRSHVVLYGERGIGKTSLLHVLTDVARESSYIVSYATCGANANFSDVFRAVLEDVP
                     LLFHRGVAPNAGEAESGGNLADRLPTGSFGPGELADLCADITGTRVLIILDEYDRVSDS
                     AFRQQVAELIKNLSDRSARVQLVIAGVASNLQELIGYAPSIRRNVIGLPMPRLEESEVQ
                     EMIALGETASGVRFDPDLTHMIHLLALGSPYFARLLCHHSALEALDQGRLTVDAGHLRR
                     ALDQAILEIEGRMPPRAVIEMRKFVGGRYDPLVAALGEASRSADGWFSGQAVVDLLPGA
                     HITAAQVEQELGELTGQLGLESETQDGDCRFRFTDDTLPVYLWLMIGRLRLDSGTLEDA
                     LATV"
     gene            11076..12374
                     /gene="dpsF"
     CDS             11076..12374
                     /codon_start=1
                     /gene="dpsF"
                     /product="polysaccharide synthesis protein"
                     /protein_id="ABW74886.1"
                     /transl_table=11
                     /translation="MKPRPGGTFMQVNFNRQARKLGAGNALARGGPVLALLATAAWTQP
                     ALAQRQAFESRPSGSERQVDIRATGSLEYDDNVVLNDQRITDGARGDVIASPGLDVTLV
                     LPRATGQLYLTGNVGYRFYKRYTNFNREQISLTGGADQRFASCVVHGEVGYQRHLTDLS
                     SILIQDTTPALNNTEEARQYTADIGCGATYGLRPAVSYTRNEVRNSLAERRYADSNTNT
                     FTAQLGLTSPALGTVAVFGRMSDSSYVHRVLPGITGQDGMKSYAAGVQLERSVANRLHF
                     NGSVNYTEVDPKLASTKGFKGVGFNVSGDYAGDQYSLQLLASRSPQPSLLLFVGYEIVT
                     AVSANATRRLSDRIQISLQGSRTWRELASSRLLTNVPISGNDNTSTLFASATFRPNRRL
                     SFVLGAGLQRRTSNTQLYSYSSKRINLSTSLSL"
     gene            12389..13306
                     /gene="dpsD"
     CDS             12389..13306
                     /codon_start=1
                     /gene="dpsD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 142.9;
                     E-value: 1.7e-43)"
                     /gene_kind="transport"
                     /product="diutan polysaccharide export protein"
                     /protein_id="ABW74887.1"
                     /sec_met_domain="Poly_export (E-value: 7.6e-20, bitscore:
                     61.5, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHIKNRFVNISTLAIAAALATPAAAQIPTRSVPAPARPRPATPPA
                     QQQNQAPSTPAAATPAQTAATVAPAATAPAGYKIGVDDVIEADVLGQTDFKTRARVQAD
                     GTVTLPYLGAVQVKGETATSLAEKLAGLLRAGGYYAKPIVSVEIVGFVSNYVTVLGQVN
                     SSGLQPVDRGYHVSEIIARAGGLRPEAADFVVLTRADGSSAKLDYKKLAQGGPNDDPMV
                     TPGDKVFVPEVEHFYIYGQINAPGVYAIRSDMTLRRALAQGGGLAPAGSVKRVKVTRDG
                     NELKLKLDDPILPGDTIVIGERLF"
     gene            13341..14687
                     /gene="dpsC"
     CDS             13341..14687
                     /codon_start=1
                     /gene="dpsC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 157.2; E-value: 9.5e-48)"
                     /gene_kind="biosynthetic-additional"
                     /product="diutan polysaccharide export protein"
                     /protein_id="ABW74888.1"
                     /transl_table=11
                     /translation="MNIIQFFRILWVRRWIILPAFLVCVTTATIVVQFLPERYKATTRV
                     VLDTFKPDPVTGQVMSSQFMRAYVETQTQLIEDYATAGRVVDELGWVNDPANISAFNNS
                     SAAATGDIRRWLAKQIIDNTKADVMEGSNILEITYSDSSPERAERIANLIRTSFLAQSL
                     AAKRQAATKSADWYAQQAEAARDSLAAAVQARTDFVKKTGIVLTETGADLETQKLQQIE
                     GQTTTATAPVAMAPSGMGPAQMQLAQIDQQIQQAATSLGPNHPTFQALQRQREVFAKAA
                     AAERAQANGVSGPARGAIESAANAQRARVLGNRQDVDKLTQLQRDVSLKQDQYMKAAQR
                     VADLRLEASSNDVGMSTLSEASAPETPYYPKVPLIIGGAAGFGLGLGLLVALLVELLGR
                     RVRSPEDLEVAIDAPVLGVIQSRASLAARLRRAQETLGEGADTHGASVN"
     gene            14687..15394
                     /gene="dpsE"
     CDS             14687..15394
                     /codon_start=1
                     /gene="dpsE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 147.2; E-value: 1e-44)"
                     /gene_kind="biosynthetic-additional"
                     /note="tyrosine-protein kinase"
                     /product="diutan polysaccharide export protein"
                     /protein_id="ABW74889.1"
                     /transl_table=11
                     /translation="MDAMTSEPLPEGDRPSAVPTTPDTIGMLEYQLVLSDPTGIEAEAI
                     RALRTRIMTQHLREGRRALAICAASAGSGCSFTAVNLATALAQIGVKTALVDANLRDPS
                     IGAAFGLAADKPGLADYLASGDVDLASIIHATRLDQLSIIPAGHVEHSPQELLASEQFH
                     DLATQLLREFDITIFDTTASNTCADAQRVAHIAGYAIIVARKDASYIRDVNTLSRTLRA
                     DRTNVIGCVLNGY"
     gene            15405..16286
                     /gene="dpsM"
     CDS             15405..16286
                     /codon_start=1
                     /gene="dpsM"
                     /note="involved in diutan capsular polysaccharide
                     attachment"
                     /product="membrane protein"
                     /protein_id="ABW74890.1"
                     /transl_table=11
                     /translation="MAATAMTRQQERKGGGYWLAVAGLAALTIPTFITLGREVWSAEGG
                     VQGPIVLATGAWMLARQCSTIEALRRPGSVLLGALFLLATLAFYTVGRVFDFISVETFG
                     LVATYLVVAYLYFGARVLRAAWFPVLWLFFLVPPPGWAVDRITAPLKEFVSYAATGLLS
                     WVDYPILRQGVTLFVGPYQLLVEDACSGLRSLSSLVVVTLLYIYIKNKPSWRYAAFIAA
                     LVIPVAVVTNVLRIIILVLITYHLGDEAAQSFLHVSTGMVMFVVALLCIFAIDWVVEQL
                     LLLRRRHHVQPA"
     gene            16270..16968
                     /gene="dpsN"
     CDS             16270..16968
                     /codon_start=1
                     /gene="dpsN"
                     /product="diutan capsular polysaccharide attachment
                     protein"
                     /protein_id="ABW74891.1"
                     /transl_table=11
                     /translation="MFNRRDLLIGAGCFAAAGASLGLKPHRRMDLLGGTKLDTLMPKAF
                     GAWKAEDTGSLIAPAREGSLEDKLYNQVVTRAFSRADGAQVMLLIAYGNAQTDLLQLHR
                     PEICYPFFGFTVVESHEQTIPVTPQVTIPGRALTATNFNRTEQILYWTRVGEYLPQNGN
                     QQMLARLKSQVQGWIVDGVLVRISTVTPEAEDGLSANLDFARELVKTLDPRVLRPLLGN
                     GLTRQLGHQV"
     gene            complement(17060..18454)
                     /gene="atrD"
     CDS             complement(17060..18454)
                     /codon_start=1
                     /gene="atrD"
                     /gene_functions="transport (smcogs) SMCOG1029:RND family
                     efflux transporter MFP subunit (Score: 77.6; E-value:
                     1.4e-23)"
                     /gene_kind="transport"
                     /product="secretion protein"
                     /protein_id="ABW74892.1"
                     /transl_table=11
                     /translation="MNAVVPMRRGGPLARMRDTVLPARVDAYDTAFLPAALEIIERPVS
                     PTARLTAKVMLAGLAITAAWLAIGKVEVVAPTQGRIAPIGETKIVQSPESGIVRRILVG
                     EGQKVAKGQVLITLDPTVSSAEAAQAKVALLSAQLDAARNQAIIDALDGRGFRFVAPAA
                     ASPGEVATHRGLARARLGQIEAALAGGRSDRGAAVSAAAEAQAQVRKLEQSLPLLEQQI
                     AANETMAAKGYVSKLRVVEMRRQLIAERQDLTAARATLAKLGQQSLSVSSLSAKTREEA
                     RAQVLQDLVKAQDEVRARGEDVAKANLRSSFRELRAPVSGTVSQLQVHTEGGVVEGAKP
                     LLSLVPDNARLEAEVMVDNSDIGFVHIGMPVKVKLQAFPYTRYGMIPGTVAGISPEAVQ
                     MKENQPPVYKARIALARGYVLAHGAQVPLRPGMLASADIVTGKRTLFSYLVGPVLETGS
                     DALHER"
     gene            complement(18451..20637)
                     /gene="atrB"
     CDS             complement(18451..20637)
                     /codon_start=1
                     /gene="atrB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="resistance (resist) ABC_efflux (Score:
                     255.2; E-value: 7.6e-78)"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 343.1; E-value:
                     5e-104)"
                     /gene_kind="transport"
                     /product="ABC transporter"
                     /protein_id="ABW74893.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 5.2e-25, bitscore:
                     78.5, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRDEMQATLQSALAAHGAAEREAELRESGLVALSLLLGAHNIAI
                     TPEQLRHALGHAEAASADDLILLAKRQQGVRAKAVEVPRGGLARQPLPAIADGPEGWFV
                     IGGLTEHGVIIQRPGHAPEQVDRDALDAIWSGALVLLTTRAVAGRPLRFGLSWFTAQFR
                     RYRTLFLEVLGITLALNLLGLAAPLLFQSVIDKVLIHNSMSTLSVLAFAFLAVSVWEVA
                     LGWIRTRLFTETTQKIDVELGARLFHHLLALPLAYFEKRRVGDTVTRVRQLETIREFLT
                     SASLTVMVDPLFTFVFLAAMLFYSPMLSGIVLVSLIAYAIVSFSVAGPLRARVEDKFEK
                     SSASNALLVESVSGIHTIKATAVEPHWQNRWERQLAAHTAASQRLINTANTGSQAIELI
                     SKLSFAAILFFGAKAVIGGAMSVGALVAFNMFAQRVSGPVIRMAQLWQDFQQVRISVER
                     LGDVLNHPVEPRPASAATLPVLRGAIRFENVSFRYAEDQPPVLSDITLDIPAGTSLGIV
                     GSSGSGKSTLAKLLQRLNLPNLGRVLVDEVDVAQLDPAWLRRQIGVVLQENLLFSRSIR
                     ENIALSNPAMPFENVVAAATLAGAHDFILRQPRGYDTEIVERGVNLSGGQRQRLAIARA
                     LVGNPRILVFDEATSALDAESEELIQNNLRAISAGRTLVVIAHRLSAVRSCDRIITLEQ
                     GRIVESGRHDELLRLGGRYADLHRRQGGYGEIAA"
     gene            21229..22641
                     /gene="dpsB"
     CDS             21229..22641
                     /codon_start=1
                     /gene="dpsB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 263.6; E-value:
                     6.2e-80)"
                     /gene_kind="biosynthetic-additional"
                     /product="glucosyl-isoprenylphosphate transferase"
                     /protein_id="ABW74894.1"
                     /sec_met_domain="Bac_transf (E-value: 1.3e-65, bitscore:
                     210.9, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAFEAQRAFEEQLRAHSRVTPSAAPVWRRSTLRMVLYTELLLLD
                     SLSILAGFHVAAGTRDGNWLSLAGINVGVFLLPIALGTALASGTYSLNCLRYPVSGVKS
                     IFSAFFFSIFVVLLGSYLLTAELPLSRVQLAEGAILSLVLLMVGRLMFRRHVRAVTGGR
                     LLDELVIIDGVSLDVAGNAVALDARIINLSPNPRDPQMLHRLGTTVIGFDRVIVACTKE
                     HRAVWALLLKGMNIKGEILVPQFNALGAIGVDAFDGKDTLVVSQGPLNMPNRAKKRALD
                     LAITVPAVLALAPLMILVAILIKLESPGPVLFAQDRVGRGNRLFKIMKFRSMRVTLCDA
                     NGNVSASRDDDRITKVGRFIRKTSIDELPQLLNVLRGDMSVVGPRPHALGSRAADHLFW
                     EIDERYWHRHTLKPGMTGLAQVRGFRGATDRRVDLTNRLQADMEYIDGWDIWRDITILF
                     KTLRVIVHSNAF"
     gene            22757..23635
                     /gene="rmlA"
     CDS             22757..23635
                     /codon_start=1
                     /gene="rmlA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 271.4; E-value:
                     1.5e-82)"
                     /gene_kind="biosynthetic-additional"
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="ABW74895.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 9.3e-12, bitscore:
                     36.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIILAGGSGTRLYPATLSISKQLLPVYDKPMIFYPLSVLMLTG
                     IRDILIISTPRDLPMFQALLGDGSAFGINLSYAEQPSPNGLAEAFIIGADFVGNDPSAL
                     ILGDNIYHGEKMGERCQAAAAQAAQGGANVFAYHVDDPERYGVVAFDPETGVATSVEEK
                     PAEPKSNWAITGLYFYDKDVVDIAKSIQPSARGELEITDVNRVYMERGDLHITRLGRGY
                     AWLDTGTHDSLHEAGSFVRTLEHRTGVKIACPEEIAFESGWLGAEDLLKRAAGLGKTGY
                     AAYLRKVATAA"
     gene            23632..24198
                     /gene="rmlC"
     CDS             23632..24198
                     /codon_start=1
                     /gene="rmlC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-6-deoxy-D-glucose-3,5-epimerase"
                     /protein_id="ABW74896.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 3.3e-74,
                     bitscore: 238.9, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQVHHHELSGVIEFTPPKYGDHRGFFSEVFKQSVLDAEGVEARW
                     VQDNQSFSAAPGTIRGLHLQAPPFAQAKLVRVLRGAIFDVAVDIRRGSPTYGKWVGVEL
                     SAEKWNQLLVPAGYAHGFMTLVPDCEILYKVSAKYSKDSEMAIRWDDPDLAIAWPDIGV
                     EPVLSEKDAVATPFAEFNTPFFYQG"
     gene            24202..25263
                     /gene="rmlB"
     CDS             24202..25263
                     /NRPS_PKS="Domain: NAD_binding_4 (6-189). E-value: 1.5e-16.
                     Score: 52.1. Matches aSDomain:
                     nrpspksdomains_rmlB_NAD_binding_4.1"
                     /codon_start=1
                     /gene="rmlB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     289.7; E-value: 4.8e-88)"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-D-glucose-4,6-dehydratase"
                     /protein_id="ABW74897.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.1e-17, bitscore:
                     52.8, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.9e-14,
                     bitscore: 43.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 6.5e-17, bitscore:
                     52.1, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQTFLVTGGAGFIGSAVVRHLVRQGARVINLDKLTYAGNPASLT
                     AIENAPNYRFVHADIADTATILPLLREEQVDVVMHLAAESHVDRSIDGPGEFIETNVVG
                     TFKLLQSALQYWRELEGEKRDAFRFHHISTDEVFGDLPFDSGIFTEETPYDPSSPYSAS
                     KAASDHLVRAWGHTYGLPVVLSNCSNNYGPFHFPEKLIPLTILNALEGKPLPVYGKGEN
                     IRDWLYVDDHAKALATIATTGKVGQSYNVGGRNERTNLQVVETICDLLDQRIPLADGRK
                     RRELITFVTDRPGHDRRYAIDATKLETELGWKAEENFDTGIAATIDWYLANEWWWGPIR
                     SGKYAGERLGQTA"
     CDS_motif       24211..24291
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_rmlB_0001"
                     /evalue="9.60E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="rmlB"
                     /protein_end="30"
                     /protein_start="3"
                     /score="27.9"
                     /tool="antismash"
                     /translation="TFLVTGGAGFIGSAVVRHLVRQGARVI"
     aSDomain        24220..24768
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rmlB_NAD_binding_4.1"
                     /evalue="1.50E-16"
                     /label="rmlB_NAD_binding_4.1"
                     /locus_tag="rmlB"
                     /protein_end="189"
                     /protein_start="6"
                     /score="52.1"
                     /tool="antismash"
                     /translation="VTGGAGFIGSAVVRHLVRQGARVINLDKLTYAGNPASLTAIENAP
                     NYRFVHADIADTATILPLLREEQVDVVMHLAAESHVDRSIDGPGEFIETNVVGTFKLLQ
                     SALQYWRELEGEKRDAFRFHHISTDEVFGDLPFDSGIFTEETPYDPSSPYSASKAASDH
                     LVRAWGHTYGLPVVLSNCSN"
     gene            25263..26129
                     /gene="rmlD"
     CDS             25263..26129
                     /codon_start=1
                     /gene="rmlD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 89.4;
                     E-value: 4.9e-27)"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-6-deoxy-L-mannose-dehydrogenase"
                     /protein_id="ABW74898.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.6e-111,
                     bitscore: 361.5, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.1e-07,
                     bitscore: 21.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILVTGHDGQVAQSLAEQAVGHELVFTTYPEFDLSKPETIEAGV
                     ARVHPDLIVSAAAYTAVDKAESEPELAMAINGDGPGVLARAGAKIGAPIIHLSTDYVFD
                     GSLDRPWREDDPTGPLGVYGATKLAGEQAVQASGATNAVIRLAWVYSPFGNNFVKTMLR
                     LAETRDALNVVEDQWGCPSSALDIATAILTVVGHWQQDGATSGLYHFAGTGETNWADFA
                     STIFAESAKRGGPSATVTGIPSSGYPTPATRPANSRLDCTRFAETFGYRAPAWQDSLNV
                     VLDRLLG"
     gene            complement(26146..26982)
                     /gene="urf31.4"
     CDS             complement(26146..26982)
                     /codon_start=1
                     /gene="urf31.4"
                     /product="hypothetical protein"
                     /protein_id="ABW74899.1"
                     /transl_table=11
                     /translation="MTTSDEEQFPPLVRLMMMQFQSGIFCNFLDRLSGHKHLLPDPNHY
                     GCGLHSTGSGGRLMLHIDASRHPNKKLSQQINCIYYCTPDWQEEWGGDLELWDEDATRC
                     VSSITPKFNRLAIFRVSGKSWHGQPFPLQTPPNIRRNSLALYYYSAEEDTEGRGYSNFV
                     RWKGRLGARQAHRAAPGEGPDPRLCADPGDQRPRQVRPQDGAELQALMGLFSRFAAAPP
                     ESPCRKVCRLDMEIRLCLGCWRSPKEIAGWSELSPKGKRAVLEALPAREREHGGGR"
     gene            complement(27312..28127)
                     /gene="urf31"
     CDS             complement(27312..28127)
                     /codon_start=1
                     /gene="urf31"
                     /product="putative glycosyl transferase"
                     /protein_id="ABW74900.1"
                     /transl_table=11
                     /translation="MLHVILTRFNIASPGREVAIRNSPGWLERRFGLFEQFCLPSIAGQ
                     TERNFHWLIYFDKDTPVEFRERIERDRQIFNFTPRYVAMFDKAMIAEDVRALATAGETL
                     IVTTRLDNDDAVSSDFVARVQDAAKEAPAQTVLNFPHGIAMRGGQLYTASDHSSPFTSL
                     VEKDVAGIETIWAKPHHELGEKWTIRQVPSKPLWLQVVHGENVTNRIKGKLVSDIDIIN
                     MFKIRSDVAARPVAAGAILWDHAVRTPIRRFREFGIRLVKPIVVRIRDR"
     gene            28445..29377
                     /gene="urf34"
     CDS             28445..29377
                     /codon_start=1
                     /gene="urf34"
                     /gene_functions="transport (smcogs) SMCOG1166:transporter,
                     EamA family (Score: 60; E-value: 4.1e-18)"
                     /gene_kind="transport"
                     /product="membrane transport protein"
                     /protein_id="ABW74901.1"
                     /transl_table=11
                     /translation="MACPYPSPVSPPRPDSIATGLALRLFAIACMSTMSALIKMSELRG
                     ASLIETMFHRQLWAVPLVTLWVTLGPGLKSLRTARFGAHVWRTAVGLTGMIFTFGAVIL
                     LPLAEAQTFQFTVPIFATLLGALILGEPTGWHRWSAVILGFVGVLIVVQPGHEAIPVFG
                     AFVGLMAALFVAIVAITLRQIGKTESAGTTVFWFSLLSVPVLGAIYAFHYKPHDAETWA
                     ILIATGLVGGVGQLALTGAMRFAPVSAVVPMDYSGLLWATLYGWLLFGVLPTFSTWLGA
                     PVIIASGLYIVYREQKLARGQASYAETPL"
ORIGIN
        1 gatcaacggc gccttgctcg gacggcacaa attcgtcctg gtcaatgtgt ccacggtcgc
       61 ctcttcgata ctgttccagc tgttcccgct tgtcgtcgcc tggatgatcg gcccggacct
      121 gcgaacgctg ctgatcgccg cgctcgttgg ccgggcggtt ccgatgatcg gcatgctgcc
      181 cgcgctgtat cgaaaccttt tgcgcggcaa cacgccgcgt tttcacgcca gcgaggcgcg
      241 cttcctgata ggctatggcg ggtgggcctc gctcacgacc gtggtagcga ccgtgctcat
      301 gatggcggac cgcttcctga ttggcgcact tcttgggccc gtcgccgtga ccatctacac
      361 ggcccccctg caactcgcac agcgcgtatc gctgctgccc tccgcactgt ccgccgcgct
      421 gttcccgcgc ctgcccagcg cgacgccggc ggagcgcatg gcgcttcaga tccgctcgct
      481 gtcgctgatc atgggcggcc ttaccgggat gatcggcggc ggactattgc tggccgcgcc
      541 gtttctcgat ctctggatcg gcaagtcgct cggccatgcg ggaacgccgg tcgcgctctt
      601 cctgttcttc ggcgcatggt ggaatgcgct ggcgatcatt tcgttcagcg gcctgcaggc
      661 gagcggacgg ccgaaagcga gcgcgatcgt ccagggggca gagctgctac ccgtgttgat
      721 cgcgctgtat gcagggatcc gatggggcgg cgtgaccggc gccgcagcgg tctttctggg
      781 acgctccgcc ctggatttcg tcctgttgac ctggcaggca ggcctgctcc gccagacggt
      841 gaagcaagta tccgtatgcg gcgccgttct caccgtcgcg atgctcgtgg gcgcgaccta
      901 tcgctattcg gtgccgctct ggtgcgtact cagcgcctgc tgcctggtcg cgctggcagc
      961 ctgctcctgg tggacattgg cgcgccagga caaggcactg ctgattggac gattgagccg
     1021 aattctacca aagcagcggc aactcgacct atagcctttc cgcaatgcac cgatggacca
     1081 caccaacccg ttttaattga cacacacaaa tgctacaccg acaaagacac aggccgagag
     1141 cgatatagaa gcgctatgcc tagccccagc gtcataaaga tgaacgggtc attgtcacct
     1201 tgcgacagga ctgaccgcgt atttaaaaga acagccagga aagttgctac ggcgagctca
     1261 agcgggtagc catctccgct catcttaaga ccacgaaacg cgagcaaaat cattaacgta
     1321 atcatcgtgc cgtatagcga aacaaaaccc agcaagccgt aatcagccgc tacggacagg
     1381 aaaccactgt cgatcgatag gaagccttgc tgattacgcc acccgacagc gccagcaccc
     1441 tctcccgggc catagccgaa gaaagggcgg cgagcgatgg caggcacgcc caagcgaaac
     1501 tgctcctgcc tgccttgatt gctaagttga gaagcgcctc caccgagaac acggttgtgg
     1561 acggcaggca cgaacatgac cgccagcgac agcgccacca tcaaggcggg atacgtcaac
     1621 gtcagcgaaa tgccgacaag cccgcccttt gtggtccgcc accgccgaat tgcccaaata
     1681 agcaaataca cggtatgcgc caccaatccc cccaccattg ccagtcgaga accgctaaga
     1741 aatccggacg caactacaag aaaatcgaag aaaatccaaa atgccaatct ccctacgcca
     1801 cgggaattcg ctatacggtg cagcacgaaa ggaatcgtca aagccgtcaa ctctccccag
     1861 acaagcggac tgctgaaagt cgtcaaaacg cggtaagtac cccggaaacc gggcgtaagc
     1921 actacggtaa gaaactgctc atcaacgcgc aggaagctcg gaatcgagta ggcccagagg
     1981 acgtgcttca cccggaactc cagcacgcca atcgccatca gcacgcccac gcaccaaaac
     2041 aagcgcgtaa cccaccactc cggggtgcgc gtgtcggtcc cgatcagcca tagcgagatg
     2101 aatgccatcg gcgtcaccgt cagaacgatg ccaatcaacc gcggaattgt ttgcgaggcc
     2161 gctggggtcg caatggaggc gacgatctgg accataatga aggcaagcaa tagtcgcgat
     2221 gggatcggcg ccgcccgcat aatcgccgcc atctcggatc gaaacttttt cgagaccgaa
     2281 agcgagatca tgagcgtgag caatgcgatc gaaccgatca tccgcctgat cgagatccaa
     2341 ggcaaaccac caacgctgag cgcaagatag ttcggccaca cgagcgccgc caccatatag
     2401 gcgaggtata gttttgccag caggcgagta ggcgcctgcc gcgcctcggg tagcgcccag
     2461 atcactacga gcgccatcag aacgaggggc acggccggga tcgccagcat ctggagcggc
     2521 agaactgcgg cgagcaggcc gtagactgcg gcaagaaaca tcacgctgac cagcagaacg
     2581 gtacgccgcg ccgcgatcgt cacgcctgat cgctcggctt tgtagacggg cagtaccggg
     2641 atcgctggct ttgtcagaaa ccgaaccagt cgcaacctgc gaagccgctg catcgctccg
     2701 tggaaggccg ggcgacgaaa cgccgaggta gtcgtcatct gcaagtcccc aacaagtccc
     2761 caagaggcgc tgccgctcgc atgatcgaag ggttcgcgaa aagcaaggtc gatacgccgc
     2821 actccctgcg atgtgccgcc ggatcgcagg agggcacggg cggcgccggc gcaaggccgc
     2881 tcaccgcccg cccccgctca ggcgcggtac aggttgtact gatccgccgt agcgctcagt
     2941 gtcgccgcgc tgcggattgc gcccatcgcc cccgcggtca tcatgtcgac accgatcttg
     3001 ctgacgagcg cgatctgcga ggacgcggca gtacctatag acagcgtact gcccaccgtg
     3061 gccaccgtcg caagcggcgt tgccgtgcta gcggcgccgg cacccgccag cagcgcagcg
     3121 gcctgcgcgg ccgcgccggt gacgaggctg tccttgaccg tcgccgccgc gctggcgctc
     3181 gacgcggtca ccagcgcctg cacctgggcg gcgctgatcg cgccatcgcg gatctcgatg
     3241 tcgccgaccg ttccgctgaa tgcggtcgag aacgggctgc cgacatacag cccccaggat
     3301 tcggcgggcc gggtcgtgcc ggtcatcgtc gctgtgccgc gttgcatgcc gtctacgtac
     3361 agaatcgcgg ttttccgcgt gctgtcgtag gtcagggcga tcttgtgtgt ggcagcatca
     3421 agcagcttgg cgccgctcgt caccattgtc tggctgacgc ccgcggcgtt gcgcatggtg
     3481 aagctcagtt ccccattggc ctgcagcgaa accgaccagc tctggaagat gccaagaatt
     3541 tgcccggccg tggccgtagc cgagtcccgc ttgaggtcga agctgagcgt gaacgccgac
     3601 aatgcgtaaa tctgccgcga atagctccgg tttagttcca cccccgtgcc cgtcgagacg
     3661 tggaaggcgc tgcccacgac cgccgacacg tccaccgcct ttgtcgtctg gccggtattc
     3721 cagtgcgaaa ggtccacgac gccgctgttg ctgaacgaca gatcgagcag cagcgacgga
     3781 tttgccgcct tcgcagtcga cagttcggta gtcacctgag cggcagcagc gctcgacacg
     3841 ggcggctggt acccgacgcc gggaacgatc aaatcgctga gccgcgccgt agccccatcg
     3901 ttgaggccat agatcttgcg gatcgttgcc gagtcactcg tcagcgtacg attgcctgtc
     3961 tgcacgatat tgctcgagga gcttgtgacg gtgatcaggt ccgcaacatt gttcttgatc
     4021 gtcgcgccat tggttttgtc gaggcgaatc caaaatgatg tgccatccac ttgcgatatc
     4081 acgctattgg attcgatatt gacattaacg ccgttaacaa cgttgatacc gtggtaataa
     4141 ccattcagat agataagatt gtttttgatg tttacattga catagggaag attaccggcc
     4201 tcgtcattca tgaaaatccc ttgcgcgcca gagcccgcgc cctgcatgat gacgttattg
     4261 gagatggtga tgttggtatt gcccttgacc ttgcccgccg tgaagaactg aatggcgtcg
     4321 ggatgttcgg tgcccacggg aaacaggttc gtgaacgaat ttccgtcgat gacaagattg
     4381 ttcatctcag tgaagttcgt atgatcgcgc cggttgtcgt ggaagctgct gttctggacc
     4441 accatgccat cgacgttgta ggcctcaagg cccagaccga agtggtcgat agacgaattc
     4501 tgcatcgtca ccgacgtgct gttgcgcacg aacaagcccg cccccttcga gagcgaaggg
     4561 tcaccagtgc cgccgctgaa ccgcacgccg tccaaaacga tgttggccga accctggatc
     4621 gtattcagtc gattccagtc atcggcgggc ttgtaatcgg tcgcagcgac catgtttttg
     4681 acggtaacgt tgctactgtt cccgatcacc agcttttgga tattgaccgg gttcgacgag
     4741 tcgagcgact caattgtcac catgctggta aacgtcttgg tcattacagt gagatctgtg
     4801 tagaccccgg cggcaagctt gatggtttcg ccacccttcg ccgccgcgat tgcagcattc
     4861 aactccgtct gattcttgac aatgatatcc ggcatgttga cttaccccgt acgcacgaac
     4921 ccgggccgat attgaccctt ccattgtcat aaataccaga acagccatga aatttgctcg
     4981 aagggataca gttaagaact cccttctacg gggccgcatg ccgggcccat gcacgcccga
     5041 ctttcgccgg caccgtctcg acggcgcaac acagtgcagc tactagggtg cgatgcagat
     5101 gctcccaacg cccgatgtca gcatactcgt ggtcgctttc aactcgaccg agtatatcga
     5161 agactgcctg cgcggcatcg ccgaaggagc gggcaagacc ccccacgaag ttctgctgat
     5221 cgacaatggc gacgggcgaa ccgaagcgct ggtccggcag cggttccacc acgtccgcat
     5281 cgttcccagt gagggcaata ttggtttcgg ggccggcaat aatcgcctgg cagcgcaggc
     5341 tgccggcccg ctcctgctgc tcgtcaaccc cgatgccatt ccccagcccg gcgcaatcga
     5401 tcagttggtc acctttgcca aacagcatcc cgaggcggcg gcatggggcg gccgttccta
     5461 ctcgcccagc ggcgatctag aacccgcaaa tttcatgtcc ctgccgacgc ccgccgactt
     5521 tctgacggcg attttcaacg cgcgtgcgct acgcagcggc gggctgcaag aaggcgcgac
     5581 cacccccgga gcggtcgagg tgttgaatgg cggcttcatg atggtacgca ccgatgtctg
     5641 gcaggcgatc ggcggttttg acgagagctt ttttctttat tcggaagaga tcgatctctt
     5701 ccagcgaatc cgcacgttgg ggcacaaggt gctcgtcgac ccctcggtca aagtggtaca
     5761 caatacgggg agtggtcagt cgatgtccca gaaccgcctg atgtatctca cgaccgggcg
     5821 catgcactat gcgcgaaagc attttggcgc actcggcacc cttgccaccg ggtgcgcgct
     5881 ttggctgatc gccgccaaat acacgttggt cggggcggca ctctggcgcc tgtcgccgcg
     5941 gacgggcacg cgatacaaag agctgagcaa cgggtggcgt gccgtattta gcaatcctgg
     6001 ccgatggtgg agcggctatc cgcgtcgcta aaagtccagc tccccccccc ctaaaggcgc
     6061 cgttgggagg cggacgcatc gttgcaacaa cgcgcccgcc tttcagacct tcagttcccc
     6121 gccggcgttg cgccgctgcc gcgaagctgc ggcggtgcgc tgtagccggc ctgatatttc
     6181 acggtttccc gcgccttctt caggcggtcg ttgagctgtg cgtcagccgc cttgccgaag
     6241 cgctcggtac gcagcccgct gagcgcgatc tcgcgcgcct ggtcggccgg caccggcagc
     6301 accgtggtcg acgtgatgat attcgcggtc agtccctgct gggtcggcag gatgaacatc
     6361 tcctgtgccg gcagcgacgc gatcttggca gcgatttccg gcggcagcgc agcggtgtcg
     6421 atctgcgacg gcgcgcgacg gaactggaca ttgtccgccg agagcttggc ggttagctgg
     6481 tccagcgtct tcagcggcgc gaattgcttg agctttgcgg ccgagctcgg cggagcgaag
     6541 acgacctgat cgatcgcgta gatcttgcgc tgcgcgaacc gctccggatg cgcggcctga
     6601 tatttctcga tctcggcatc ggtcggctgg gcgatgccgc cggcgatctt gtcgcgcagc
     6661 atggcggtga ggatcagctc gtcggcccgg cgctcctgga tcaggaaggc aggcgtcttg
     6721 tccagcttct gctcgcgggc gaccttggcg aggatcttgc gctcgatgat gcgctgcagc
     6781 gccagctgct cggccagctt gcgatcggtc cccgggggta cctgggaggc ctgcagttcg
     6841 gcattcagct cgaagacggt gatttcttcg ccatcgacgc tggcgaccac ctgccccttg
     6901 tcgagcttgc cgcccttgcc gccacatccg gagacggcca gcgcggccgc agccaccgcc
     6961 gtaaccaggt acaatttctt catgaagacc tccccgccgg cacggaattg cgcacggcac
     7021 aaacttctac ttgaacctat tcggacgggc gggcatccgc aatagcgttg gcagtgcagc
     7081 atggttctaa gcggagccag gcggcaacaa gggggacgag atggcagaag cgaacgcggt
     7141 agatggaaag gcctccaagc cgctgaaaat gtgccttgca gcgtcgggcg gcggccatct
     7201 ccggcaaatc ctcgatctgg aatcggtgtg gcgcgaacac gattatttct tcgttactga
     7261 agataccgcg ctcggccgga gccttgccga aaaacatccc gtcgaactgg tggagcacta
     7321 tgcgctcggc caggccaagc tgggccatcc cttgcgcatg ctgggcggcg catggcgcaa
     7381 cctgcgccag agcctttcga tcctgcgccg gcacaagccg gatgtggtga tttccaccgg
     7441 cgcgggcgca gtctatttca ccgcgctgct cgccaaactg tcgggcgcca agttcgtcca
     7501 tatcgaaagc ttcgcgcgct tcgaccaccc gtctgccttc ggcaagatgg tgaagggcat
     7561 cgcgacggtg acgatcgtcc agtcggcggc gctgaaagaa acctggcctg atgccgagct
     7621 gttcgatccg ttccgcctgc tcgatacacc gcgcccgccc aagcaggcgc taatcttcgc
     7681 gacggtcggc gccaccctgc ccttcccgcg gctggtgcag gcagtgctcg acctgaagcg
     7741 cgccggcggg ctgccgggca agctgatcct gcaatatggc gaccaggacc tgcccgatcc
     7801 cggcatcccc gacgtcgaga tccgccgtac catcccgttc gacgatctgc agctgctgct
     7861 gcgcgatgcg gatatggtga tatgccacgg cggcaccgga tcgctggtca cggcgctgcg
     7921 cgccggctgc cgggtcgtcg cctttccgcg ccgccacgat ctgggcgagc attatgacga
     7981 tcaccaggaa gagatcgccc agaccttcgc cgaccggggc ctgctccagg cggtgcgcga
     8041 cgagcgccag ctcggcgccg ctgtggaagc ggccaaggca accgagccgc agctggcgac
     8101 caccgaccac acggccctcg cggcgcggct gcgccagctg ctggcgcagt ggagtgccaa
     8161 gcgatgagca cgccccggat cagcgtcgtc atcccgcact ataacgatcc gcaatccttg
     8221 cggctctgcc tggatgcgct ggagcggcag acgatcggtc gcgacgcgtt cgagatcatc
     8281 gtcggcgaca acaattcgcc ctgtgggctc gcggcggtgg aggcggcggt cgccggacgt
     8341 gcgcggatcg tgaccattct ggaaaagggg gcgggccccg cgcgcaacgg ggcggcagcc
     8401 gcagcgcgtg gcgagatcct cgcctttacc gacagtgact gcgtggtgga gcccggctgg
     8461 ctggcgggcg gcacgaccag ggtcgcgcct ggccgtttca tcggcgggca catgtatgtg
     8521 cgcaagcccg aagggccgcc gaacggcgcc gaggcgctgg agatggcgct ggcgttcgac
     8581 aatgaaggct atgtgcggcg cacccagttc acggtcaccg caaacctgtt cgtgatgcgc
     8641 gccgatttcg aacgggtcgg cggcttccgc gttggcgtgt ccgaggatct ggaatggtgc
     8701 caccgggcga tcgccagcgg cctcaccatc aactatgcac cggatgcatc ggtgggccac
     8761 ccgccccggc ccgactggtc ggccctgctg gtgaagacgc ggcgcatcca gcgcgaactc
     8821 tatctgttca acatcgagcg gccgaagggc aggctgcgct ggctggtccg ttccgtggcg
     8881 caaccggcga tgatcccaca ggacgtggcc aagatcctgc gcacaccggg taccaagggc
     8941 gcgcgcctcg ctgcggtcac cacgctggtc cggctgcggc tgtggcgcgg cggcgccggc
     9001 ttgttgcagt tgctcggccg cgacatctga tcgaccggcg atcggccgac gagcgcgtcg
     9061 ccggccgatc gcattgcatc agacggtggc cagcgcgtct tccagcgtgc cgctgtcgag
     9121 ccgcaggcgg ccgatcatca gccacagata gaccggcagc gtatcgtcgg tgaagcggaa
     9181 gcggcaatcg ccgtcctgcg tttcggattc gaggccgagt tgaccggtga gctcgcccag
     9241 ctcctgctcg acctgcgccg ccgtgatgtg cgcgcccggc agcagatcca ccacggcttg
     9301 gccgctgaac cagccatccg ccgagcgcga ggcctcgccc agcgccgcga cgagtggatc
     9361 gtagcggccg ccgacgaact tgcgcatctc gatcaccgcg cgcggcggca tgcggccctc
     9421 gatctcaagg atcgcctggt cgagcgcacg acgcagatgc ccggcgtcga ccgtgaggcg
     9481 gccctggtcc agggcttcca gcgcggaatg gtggcacagc agccgcgcga aatagggcga
     9541 ccccagcgcg agcaggtgga tcatgtgagt caggtccgga tcgaagcgaa cgcccgaggc
     9601 ggtttcgccg agcgcgatca tctcctgcac ctccgattcc tccagccggg gcatcggcag
     9661 gccgatgacg ttgcggcgga tcgacggcgc ataaccgatc agctcctgca ggttcgaggc
     9721 gacgcccgcg atcaccagct ggacgcgcgc cgaacggtcc gacaggttct tgatcagctc
     9781 ggcgacctgc tgacggaagg cggaatcgct gacgcgatca tattcgtcga ggatgatcag
     9841 cacgcgtgtg cccgtgatgt cggcgcacag gtcggccagt tcgccgggcc cgaagctgcc
     9901 cgtcggcagg cggtcggcca agttgccgcc gctctccgcc tcgccggcgt tgggcgccac
     9961 gccgcgatgg aacagcagcg gcacgtcttc cagcacggcg cggaagacat cgctgaaatt
    10021 cgcgttcgca ccgcaggtcg catagctgac gatatagctg gattcgcggg cgacatcggt
    10081 cagcacgtgg agcagcgagg tcttgccgat gccgcgctcg ccatagagca cgacatggct
    10141 gcgctggctc tcgatcgagg agattaggcg cgccagcacg ccgaggcgcc cggcgaagct
    10201 cgaccgatcg gccaccggct gggtgggtgt gaagaaggtc gccagcgcga accgggcgcg
    10261 cgtgatctcg cggcgctcgt cgcggcggcg atccagcggg cggtccagcg cggaggcacg
    10321 gaaggttggg aaatccgggc gaccacggcc gctatgggca tcgcgatgcg gcaccactgt
    10381 cgcagtcagc gggaaatagc cctcttcttc aggttcttct cgacggccga acggccacaa
    10441 gaatctcagc gcggaaccta cagccactcg aacacctctt aaattcgtgc gccatcggca
    10501 ccgacggcgc accctggttc gcgccccctg gcgccccctc ctaacgaacc cacgccttgc
    10561 ctggcctatc ggcgcttgaa gaactcgtac ggtttgatca ccaaggcgat gtacgccagg
    10621 accagagcga tcgtcaaaat tgcaaagacg tgataattct cattgcccag ataattggcg
    10681 acggcgcaac cgactgcggg cggcaaatag ctgatcatcg tgtcccggac tgccgaatcg
    10741 gcttgggacc gttgcaggaa tataacgatc aggccggcaa atatcgcgat ggtgacccaa
    10801 tcatagggcg tctgcatgca tgtcctttct attcgacacc ggaatcgaac catttccggc
    10861 gacgctattg cacgcactag cagtgcgcgc ggccgctcgc taggtagcgc cgcaccggat
    10921 aaaccgacgt taagatggcg cggctcgatc gaaatggagt caaacgggct tgcccggccg
    10981 accgaagcat ggcgccatgg cgcatgcacc gtattgtgac cacgcaaacc gcgagggtca
    11041 ttcgatgcgg ttgcttgtac aggaggccat tgataatgaa gccgagaccc gggggaacct
    11101 ttatgcaagt aaatttcaat cgacaggctc gcaagctcgg tgccggcaat gcgctcgcgc
    11161 ggggggggcc cgtgcttgcg ctgcttgcga ccgcggcatg gacacaacct gcgctggcgc
    11221 agcgacaggc atttgagtcc cgcccctccg gtagcgagcg acaggtcgat attcgcgcga
    11281 cggggtcgct ggaatatgac gacaacgtcg tgctgaacga ccagcggatc acggacggcg
    11341 cgcgtggcga tgtgatcgca tcgcccgggc tggacgtgac cctagttctg ccccgcgcca
    11401 ccgggcagct ctacctcacc ggcaatgtcg gatatcgctt ttacaagcga tataccaact
    11461 ttaaccgcga gcagatctcg ctcaccggcg gcgcagatca gcggttcgcc tcctgcgtcg
    11521 tgcacgggga agtcggctat cagcgccacc tcaccgacct gtccagcatc ttgatccagg
    11581 acaccacgcc tgcgctcaac aacaccgaag aggcccggca gtacaccgcg gatatcggct
    11641 gcggcgcgac ctacggcctg cggcctgccg tttcctacac ccgcaacgaa gtgcgcaaca
    11701 gccttgccga gcgccgatac gcggactcga ataccaacac ctttaccgca cagcttggcc
    11761 tgacttcgcc tgccctgggg accgtggcgg tatttgggcg tatgtccgac agcagctatg
    11821 tccatcgcgt ccttcccggc attaccggcc aggacgggat gaagagctac gcggccggcg
    11881 tccagctcga gcgctcggtg gccaaccgac tccatttcaa cggctcggtg aattacaccg
    11941 aggttgaccc aaagctcgca tccaccaaag gattcaaggg cgtaggattt aacgtttccg
    12001 gcgattatgc tggtgatcag tacagcctcc aattgctggc ttcacgatcg ccccagcctt
    12061 cacttcttct gttcgtgggt tacgagattg tgacagcggt ttcggcgaat gcgacgcgcc
    12121 ggctgagcga tcgcattcag atatcgctgc aaggcagccg aacctggcgc gagctcgcgt
    12181 cttcgcggct gctcaccaac gtgccgattt ccggcaacga caacacctcg acgttgttcg
    12241 cctccgctac cttccggccg aatcgccggc tgagctttgt gctgggtgcc ggccttcagc
    12301 ggcgcaccag caacacgcag ctatacagtt acagctccaa acgcatcaat ctctcgacgt
    12361 cgctttcgct ctgacaaggg ccgtaatcat gcatatcaag aatcgcttcg tgaatatctc
    12421 gacgttggcc atcgccgccg cgctggccac gccggcggcg gcgcagatcc ccacgcggtc
    12481 cgtgcccgcg ccggcccgcc cgcggcctgc aacgccgccg gcgcaacagc agaaccaggc
    12541 gccgtcgacg cccgcagcgg caaccccggc gcagaccgcc gcaaccgttg cccctgcagc
    12601 aaccgcaccc gcaggttaca aaatcggcgt ggacgacgtg atcgaggccg acgtgctcgg
    12661 ccagaccgac ttcaagacgc gcgcccgtgt gcaggcggac ggcacggtga ccctgcccta
    12721 tctgggcgcc gtgcaggtca agggcgagac cgcgacctcg ctcgccgaaa agctggccgg
    12781 gctgctgcgc gccggcggct attatgccaa gccgatcgtc agcgtcgaaa tcgtcggttt
    12841 cgtcagcaac tatgtgacgg tgctgggcca ggtgaacagt tccggcctgc agccggtcga
    12901 ccgcggctat cacgtttccg agatcatcgc ccgtgccggc ggcctgcgcc ccgaagcggc
    12961 cgatttcgtc gttctcaccc gcgccgatgg ctccagcgcc aagctggact acaagaagct
    13021 cgcccaaggt ggccccaatg acgatccgat ggtgacgccc ggggacaagg tctttgtccc
    13081 ggaagtcgag catttctaca tttatggtca aattaacgcg cctggcgtat acgcgattcg
    13141 atcggacatg acgctccgtc gcgcgctggc ccagggcggt gggcttgccc ccgcaggctc
    13201 cgtcaagcgt gtgaaggtca cgcgggatgg caatgaactc aagttgaagc tggacgatcc
    13261 gattctccca ggcgacacga tcgtcatcgg cgaacgattg ttctgatctt ggcaacgatg
    13321 gcagcggacg aggcccacca gtgaatatca ttcagttctt ccgcattctg tgggtgcgcc
    13381 gatggatcat cctcccggcg tttctcgttt gcgttaccac tgccaccatt gtggtccagt
    13441 ttctgcccga acgctacaag gccactacgc gggtggtgct cgacacgttt aagcccgatc
    13501 ccgtcaccgg acaggtgatg agctcgcagt tcatgcgcgc ctatgtcgag actcagaccc
    13561 agctgatcga ggactatgcg accgccggtc gcgtggtcga cgaactgggc tgggtgaatg
    13621 atccggcgaa catctccgcg ttcaacaact cgtccgcggc tgccaccggc gacatccgcc
    13681 gctggctcgc caagcagatc atcgacaata ccaaggccga tgtgatggag gggagcaaca
    13741 tcctcgaaat cacctattcg gacagctcgc ccgagcgcgc cgaacgcatc gccaacctga
    13801 tccgcacctc gttcctcgcc cagtcgctcg ccgccaagcg ccaggccgcg accaagtcgg
    13861 ccgactggta cgcccagcag gccgaagctg cccgcgattc gctcgctgcg gcggtccagg
    13921 cccgcaccga tttcgtgaag aagaccggca tcgtgctgac cgaaaccggc gccgacctgg
    13981 aaacccagaa gctccagcag atcgaggggc agacgacgac cgccaccgcc ccggttgcca
    14041 tggcccccag cggcatgggc ccggcgcaga tgcagctcgc ccagatcgac cagcagatcc
    14101 agcaggcagc gaccagccta ggtccgaacc acccaacttt ccaggccttg cagcggcagc
    14161 gcgaagtgtt cgccaaggca gcggcggcgg aacgcgcgca ggcgaacggc gtatccggtc
    14221 cggcacgcgg ggccatcgaa agcgcagcca acgcccagcg cgcgcgggtt ctcggcaatc
    14281 gtcaggatgt cgacaagctt acgcagctgc agcgtgacgt ctcgctgaag caggatcagt
    14341 acatgaaggc ggcacagcgc gtcgccgatc tgcggctgga agcaagcagc aacgatgtcg
    14401 gcatgtcgac gctcagcgaa gcatcggcgc cggaaacgcc ctattacccc aaggtgccgc
    14461 tcatcatcgg tggtgcagcc ggcttcggcc tcgggctcgg tctgctggtc gcgctgctcg
    14521 tcgagctgct cggccgccgc gtccgcagcc ccgaggatct ggaagttgcg atcgatgcac
    14581 cggtgctggg cgtgatccag agccgcgcct cgcttgccgc ccgccttcgc cgcgcccaag
    14641 aaaccctcgg cgaaggtgcc gacacgcacg gagcttcagt aaactgatgg acgcgatgac
    14701 cagcgaaccg ctgcccgaag gcgatcgtcc gagcgccgtg ccgaccacgc cggatacgat
    14761 cggcatgctc gaataccagc tcgtcctctc cgatccgacc gggatcgagg cggaagcgat
    14821 ccgcgcgcta cgcacgcgca tcatgaccca gcacctccgc gagggccggc gcgcgctcgc
    14881 gatctgcgcc gcctcggcgg gatccggctg cagcttcacc gccgtcaatc tggcgacggc
    14941 gctggcgcag atcggcgtta agactgcgct ggtcgatgcc aatctgcgcg atcccagcat
    15001 cggcgcagcc ttcggcctcg ccgccgacaa gcccggcctg gccgattatc tcgcctcggg
    15061 cgatgtcgac ctcgcctcga tcatccatgc gacccgcctc gaccagctct cgatcatccc
    15121 ggccgggcat gtcgagcaca gcccgcagga actgctcgcg tccgaacagt tccatgatct
    15181 ggcgacgcag ctgctgcgcg agttcgacat cacgatcttc gacaccacgg cgtccaacac
    15241 ctgcgccgac gcgcagcgtg tcgcgcatat cgccggctat gcgatcatcg tggcgcgcaa
    15301 ggatgcgagc tacatccgcg acgtgaacac gctcagccgc acgctgcgtg cagaccgcac
    15361 caacgtcatc ggctgcgtac tgaacggcta ttgatttgga ccatatggca gcgaccgcga
    15421 tgacgcggca gcaggagagg aagggcggtg gctattggct ggccgttgcc ggtcttgccg
    15481 cgctaaccat cccgaccttc atcaccctgg gtcgcgaggt ttggagtgcg gaaggcggcg
    15541 tgcagggtcc gatcgtgctc gccacgggcg cctggatgct ggcccgccag tgctcgacga
    15601 tcgaggcgct acgccgcccc ggcagcgtgc tgctcggcgc gctgttcctg ctggcgacgc
    15661 ttgccttcta caccgttgga cgggtgttcg acttcatcag tgtcgaaacc ttcggactgg
    15721 tcgcgaccta tctggtcgtc gcctatctct atttcggtgc cagggtgctc cgtgccgcct
    15781 ggttcccggt gctgtggctg ttcttcctgg tgccgccgcc cggctgggcc gtcgaccgca
    15841 tcaccgcacc gctcaaggag ttcgtctcct atgcggcaac gggcctgctt tcctgggtgg
    15901 attatccgat cctgcgccag ggcgtgacac tgttcgtcgg cccctatcag ctgctcgtcg
    15961 aagatgcctg ttcgggtctg cgctcgctgt ccagcctggt cgtcgtgacg ctgctctaca
    16021 tctacatcaa gaacaagccg tcctggcgct acgcggcgtt catcgcagcg ctggtgatcc
    16081 cggtggcagt ggtgaccaac gtcctgcgga tcatcatcct ggtactgatc acctatcatc
    16141 tgggcgacga ggcggcgcag agcttcctcc acgtctccac cggcatggtg atgttcgtgg
    16201 tcgccctgct ttgcatcttc gcgatcgact gggtggtcga gcaacttctt ctcctgcgtc
    16261 ggaggcatca tgttcaaccg gcgtgacctg ctgatcggcg caggctgctt cgccgccgct
    16321 ggcgcctcgc tcggcctgaa gccgcaccgg cggatggacc tgctgggcgg caccaagctc
    16381 gacacgctga tgcccaaggc attcggcgca tggaaggcag aggataccgg ttcgctgatc
    16441 gcgccggcgc gcgaaggcag cctggaggac aagctctaca accaggtggt cacccgcgcc
    16501 ttctcccgcg cggacggtgc ccaagtgatg ctgctgatcg cctatggcaa cgcccagacc
    16561 gatctactgc agctgcaccg gccggaaata tgctacccgt tcttcggctt caccgtggtg
    16621 gaaagccatg agcagaccat cccggtgacg ccgcaggtga cgatccccgg tcgcgcgctg
    16681 accgccacca acttcaaccg caccgagcag atcctctact ggacccgcgt cggcgaatat
    16741 ctgccgcaga acggcaatca gcagatgctc gcgcggctga agagccaggt ccagggctgg
    16801 atcgtcgacg gtgtgctggt gcgcatctcg acggtgacgc ccgaggcgga agatggcctg
    16861 agcgccaatc tcgatttcgc gcgcgagctg gtgaagacgc tcgacccgcg cgtgctgcgc
    16921 ccgctgctcg ggaacgggct cacacggcag ctcggtcacc aggtctgaac cggtgcgccg
    16981 cacgcggcgc ccccggcaac aaaaaaggag cggcgcgggc cgccgccgct ccctctcctt
    17041 ctcatgcggc gccctgccct caccgctcgt gcagcgcgtc actccccgtc tcgagcacgg
    17101 gccccaccag atagctgaac agggttcgct tgccggtgac gatgtccgcg ctcgcgagca
    17161 tccccggccg cagcggcacc tgtgcgccat gggccagcac atacccgcgc gccagcgcga
    17221 tccgcgcctt gtagaccggc ggctggttct ccttcatctg caccgcctcg gggctgatgc
    17281 ccgccaccgt gccgggaatc atgccgtagc gggtataggg aaaggcctgc agcttcacct
    17341 ttaccggcat gccgatgtgg acgaagccga tgtcgctgtt gtcgaccatc acctcggcct
    17401 cgagccgggc attgtcggga accaggctga ggagcggctt ggccccttcc accacgccgc
    17461 cttcggtgtg gacctgcagc tgcgagacgg taccgctcac cggcgcgcgc agttcgcgga
    17521 acgagctgcg cagattcgcc ttggcgacgt cctcgccgcg ggcacgcacc tcgtcctgcg
    17581 ccttgaccag atcctgcagc acctgcgccc gcgcctcctc gcgcgtcttg gccgacaggc
    17641 tggagacgct cagcgactgc tggccgagtt tggcgagcgt agcgcgcgcc gccgtcaggt
    17701 cctgccgctc ggcgatcagc tggcgacgca tctccacgac gcgcagcttc gagacatagc
    17761 ccttggcggc catcgtctcg ttcgcggcga tctgctgttc gagcagcggc agcgactgtt
    17821 cgagcttccg cacctgtgcc tgcgcctcgg ccgcggccga gacggcggca ccgcgatcgg
    17881 agcggccgcc ggccagcgcc gcctcgatct ggcccagccg ggcgcgggcg aggccgcgat
    17941 gcgtcgccac ttcgcccggg ctggcggcgg caggcgcgac gaagcggaag cccctgccgt
    18001 ccagcgcgtc gatgatcgcc tggttgcgtg cggcgtcgag ctgggcgctg agcagcgcca
    18061 ccttcgcctg tgccgcctcc gccgacgaca cggtcgggtc gagcgtgatc agcacctggc
    18121 ccttggcgac cttctgcccc tcgcccacca ggatgcggcg gacgatcccc gattcgggcg
    18181 actggacgat cttggtctcg ccgatcggcg cgatccgccc ctgcgtcggc gcgacgactt
    18241 cgaccttgcc gatcgccagc caggcggcgg tgatcgccag cccggccagc atcaccttgg
    18301 cggtaagccg cgcggtgggc gaaaccggcc gctcgatgat ctccagcgcg gcaggcagga
    18361 aggcggtgtc ataagcgtcg acgcgggcag gcagcacggt atcgcgcatg cgggcgagcg
    18421 ggccgccgcg gcgcatcgga acaacggcgt tcatgcggca atctccccat agccgccctg
    18481 gcggcggtgc aggtcggcat agcggccgcc caggcgcaac aattcgtcgt gtcggccgct
    18541 ctcgacgatg cggccctgtt cgagcgtgat gatccggtcg cagctgcgca ccgcgctcag
    18601 gcgatgcgcg atcaccacga gcgtgcggcc ggccgagatg gcgcgcaggt tgttctggat
    18661 cagctcctcg ctctcggcat cgagcgccga ggtcgcttcg tcgaacacca ggatgcgcgg
    18721 attgccgacg agcgcgcggg cgatggcgag ccgctggcgc tggccgccgg agagattgac
    18781 gccgcgctcg acgatctcgg tgtcatagcc gcgcggctgg cgcaggatga aatcatgcgc
    18841 gccggccagc gtcgccgccg cgacgacatt ctcgaacggc atggcggggt tggagagcgc
    18901 gatgttctcg cggatcgagc ggctgaacag cagattctcc tgcagcacga cgccgatctg
    18961 gcgacgcagc caggcgggat cgagctgcgc cacgtcgacc tcgtcgacca gcacgcggcc
    19021 gagattcggc aggttgagcc gctggagcag cttggccagc gtcgacttgc ccgagcccga
    19081 cgaaccgacg atgccgagcg aggtgcccgc cggaatgtcg agcgtgatgt cgctcagcac
    19141 cggcggctgg tcctcggcat agcggaagct gacattctcg aagcgaatcg caccgcgcag
    19201 caccggcagc gtcgccgccg aggccgggcg cggttccacc ggatggttga gcacgtcgcc
    19261 cagccgctcg accgagatgc gcacctgctg gaaatcctgc cacagctgcg ccatgcggat
    19321 caccggcccg gacacgcgct gggcgaacat gttgaacgcc accagcgcgc ctacgctcat
    19381 cgcgccgccg atcaccgcct tggcgccgaa gaacaggatc gccgcgaagc tcagcttcga
    19441 gatcagctcg atcgcctggc tgccggtgtt ggcggtattg atcagccgct gcgacgcggc
    19501 ggtatgggcg gcgagctggc gctcccagcg attctgccag tgcggctcga ccgcggtcgc
    19561 cttgatcgtg tggatgcccg agacgctctc gacgagcagc gcgttgctgg cggagctctt
    19621 ctcgaacttg tcctccaccc gcgcgcggag cggcccggcg acgctgaacg atacgatcgc
    19681 ataggcgatc agcgacacga gcacgatgcc cgagagcatc ggcgagtaga acagcatcgc
    19741 ggcgaggaac acgaaggtga acagcgggtc caccatcacc gtcagcgagg cgctggtaag
    19801 gaattcgcgg atcgtctcga gctggcggac gcgggtgacg gtgtcgccca cgcggcgctt
    19861 ctcgaaatag gcgagcggca gcgccagcag gtggtggaac agccgggcac ccagctcgac
    19921 gtcgatcttc tgcgtcgtct cggtgaacag gcgggtgcgg atccagccga gcgccacttc
    19981 ccacaccgaa accgccagga aggcgaaggc gagcacgctc agcgtgctca tgctgttgtg
    20041 gatcagcacc ttgtcgatca cgctctggaa caacagcggc gcggcgaggc cgagcaggtt
    20101 gagcgcgagg gtgatgccga gcacctcgag gaacagcgtg cgatagcgcc ggaactgcgc
    20161 ggtgaaccag gagaggccga accgcagcgg ccgtcccgcc accgcgcggg tggtgagcag
    20221 caccagcgcg ccggaccaga tcgcgtccag cgcgtcccgg tcgacctgtt ccggggcatg
    20281 gcccgggcgc tggatgatca cgccatgttc ggtcaggccg ccgatcacga accagccttc
    20341 gggcccgtcg gcgatcgcgg gcagcggctg gcgggcgagt ccgccgcgcg gcacctcgac
    20401 ggccttggcg cgcacgccct gctggcgctt ggccaggagg atcaggtcgt cggcgcttgc
    20461 cgcctcggca tggcccagcg cgtggcgcag ctgttcgggc gtgatggcga tgttgtgcgc
    20521 gccgagcagc agcgacaacg ccaccagtcc ggattcgcgc agctccgcct cgcgctccgc
    20581 cgccccatgg gccgcgagcg cgctctgcag ggtggcctgc atttcgtcgc gtgtcatttc
    20641 cggaactctg cctccatggc gatactgaga gcgccatgat gaagaaggct ggtaaagact
    20701 cacttaatcc tagcttttct ggtatttacc cgtagctgcc gacccgattt gggacaggcc
    20761 tggcttagca ggtccttaaa ctcgaccgac tataccgcga cgccgaggag ggggaggatt
    20821 ggcgccgcat cgcgcggcga aacgcgggtg cgtcgcaaca tttcgccgga gtcgatccgt
    20881 cgcgaatgct gcacccgcga acgcaatgac ggccgccacg caatccggct tgatcccggg
    20941 cggcggatcg cgataagccg cgccacggtc gccaaaactc gtcgaaataa ccgacaaaac
    21001 cacggcatat ggctggatat tgcagcgttt gccctgcgtt tccgtcgttc aaccgccctt
    21061 cgaatcaggc aggcccagcg tgaccatgat tgatcttcct cttggaacgg cacactttgg
    21121 tcgacacgga gacttccggt cgggcaattg tcccgttata gtgcaatgca acaggccgaa
    21181 tcggccgctg tcggcgtgca cattccgttg agggagcccg atgaggcaat gaacgctttc
    21241 gaagcacagc gcgcctttga ggagcaactt cgggcgcatt cccgggttac gccatctgcc
    21301 gctcccgtgt ggcgtcgctc gacgctgcgg atggtcctct ataccgagtt gctgctgctg
    21361 gacagtctct cgatcctggc cggattccac gtcgcggcgg gcacgcgcga cggcaactgg
    21421 ctgtcgctgg cgggcatcaa cgtcggcgtc ttcctgctgc cgatcgctct cggcaccgcg
    21481 ctcgcaagcg gcacctactc gctgaactgc ctgcgctacc cggtcagcgg cgtgaagagc
    21541 atcttctcgg cattcttctt ctcgatcttc gtcgtcctgc tcggcagcta cctgctgacg
    21601 gccgagctgc cgctgtcccg cgtgcagctg gcggagggcg cgatcctctc gctggtcctc
    21661 ctgatggtgg gccgcctgat gttccgccgc cacgtccgcg cggttaccgg cggcaggctg
    21721 ctcgacgaac tggtcatcat cgacggcgtc tcgctcgacg tcgcgggcaa tgcggtcgcg
    21781 ctcgacgcgc ggatcatcaa tctctcgccg aacccgcgcg atccgcaaat gctgcatcgc
    21841 ctgggcacca ccgtgatcgg gttcgaccgg gtgatcgtcg cctgcaccaa ggagcatcgc
    21901 gcggtctggg cgctgctgct caagggcatg aacatcaagg gcgagatcct cgtcccccag
    21961 ttcaatgcgc tgggcgcgat cggcgtggac gcctttgacg ggaaggatac gctggtcgtc
    22021 tcgcagggcc cgctcaacat gcccaaccgc gcgaagaagc gcgcgctcga tctcgcgatc
    22081 accgtaccgg ccgtgctcgc gctggcgccg ctgatgatcc tggtggcgat cctgatcaag
    22141 ctggagagcc cgggcccggt gttgttcgcg caggatcgcg tcggccgcgg caaccggctg
    22201 ttcaagatca tgaagttccg ctcgatgcgc gtaacgctgt gcgacgcgaa cggcaacgtc
    22261 tcggccagcc gcgacgacga tcgcatcacc aaggtcggcc gcttcatccg caagaccagc
    22321 atcgacgaac tgccgcagct gctgaacgtg ctgcgcggcg acatgagcgt cgtcggcccg
    22381 cggccgcatg cgctgggctc gcgcgccgcc gatcacctgt tctgggaaat cgacgagcgc
    22441 tactggcacc gccacacgct caagccgggc atgaccggtc tggcccaggt gcgcggtttc
    22501 cgcggggcga ccgatcgccg cgtcgatctg accaaccggc tccaggcaga catggaatat
    22561 atcgacggat gggatatctg gcgcgatatc acgatcctgt tcaagacgct gcgggtgatc
    22621 gtgcattcga acgcattctg atccgcgcac gacgctgggc cgcagcctcg atccgcaaat
    22681 ggattgacag cggcccggct tccgttttct cgtttgattt tcgttgcggc cggtccgcgc
    22741 catgggggat tactgaatga agggcatcat ccttgcgggg ggcagcggga cgcgcctgta
    22801 ccccgcaacg ctatcgatct cgaagcagct gcttcccgtc tatgacaagc cgatgatctt
    22861 ctatccgctg tcggtgctga tgctcaccgg catccgggac atcctgatta tctccacccc
    22921 gcgcgacctg ccgatgttcc aggcgctgct gggcgacggc tcggccttcg gcatcaacct
    22981 cagctatgcc gagcagccct cccccaacgg gctggccgaa gcgttcatca tcggcgcgga
    23041 tttcgtcggc aacgatccca gcgcgctgat cctgggcgac aacatctatc acggcgaaaa
    23101 gatgggcgag cgctgccagg cagccgcagc gcaggcagcg cagggcggtg caaacgtctt
    23161 cgcctatcat gtcgacgacc ccgagcgcta cggcgtggtc gcgttcgacc cggagacggg
    23221 cgtcgccacc agcgtcgagg aaaagccggc cgagcccaag tccaactggg cgatcaccgg
    23281 cctgtatttc tacgacaagg acgtggtcga catcgccaag tcgatccagc cctcggcgcg
    23341 cggcgaactc gagatcaccg acgtcaaccg cgtttacatg gagcgcggcg acctgcacat
    23401 cacgcgcctc ggccgcggct atgcctggct cgacaccggc acgcatgaca gcctgcacga
    23461 agccggctcg ttcgttcgca cgctcgagca tcggacgggc gtgaagatcg cctgcccgga
    23521 ggaaatcgcc ttcgaaagcg gctggctcgg cgccgaagac ctgctcaagc gcgccgccgg
    23581 cctcggcaag accggctatg ccgcctatct ccgcaaggtt gcgaccgcag catgacccag
    23641 gtccatcatc acgaactgtc cggcgtcatc gagttcacgc cgcccaaata tggcgaccac
    23701 cgcggcttct tctccgaagt gttcaagcag tcggtgctcg atgccgaagg cgtcgaggca
    23761 cgctgggtgc aggacaatca gagcttctcg gcggccccgg gcacgatccg cggcctgcat
    23821 ctccaggcgc cgcccttcgc ccaggccaag ctggtccgcg tgttgcgcgg cgcgatcttc
    23881 gacgtcgcgg tcgacatccg tcgcggctcg cccacctatg gcaaatgggt cggcgtcgag
    23941 ctctcggccg agaagtggaa ccagctgctg gtccccgccg gctatgcgca cggcttcatg
    24001 acgctcgttc cggattgcga gatcctctac aaggtcagcg ccaaatattc gaaggattcg
    24061 gagatggcga tccgttggga cgatcccgat ctcgccatcg cctggccgga catcggcgtc
    24121 gagccggtcc tctccgaaaa ggacgcggtc gccacgccct tcgccgaatt caacaccccc
    24181 ttcttctatc agggctgagc catgcagcag accttcctcg tcaccggcgg cgccggcttc
    24241 atcggctcgg cggtggtgcg ccacctcgtc cgccagggcg cgcgcgtcat caatctcgac
    24301 aagctcacct atgccggcaa cccggcctcg ctgactgcga tcgagaacgc gcccaactat
    24361 cgcttcgtcc atgccgacat cgccgacacc gcgacgatcc taccgctgct gcgcgaggag
    24421 caggtcgatg tggtgatgca cctcgccgcc gagagccatg tcgatcgctc gatcgacggc
    24481 cctggcgagt tcatcgagac caatgtcgtc ggcaccttca agctgctcca gtcggcgctg
    24541 caatattggc gcgagctgga gggcgagaaa cgcgacgcgt tccgcttcca ccacatctcc
    24601 accgacgaag tgttcggcga cctgccgttc gacagcggca tcttcaccga agagacgccc
    24661 tatgatccct cctcgcccta ttcggcgtcg aaggcggcga gcgaccatct ggtgcgcgcc
    24721 tggggccaca cctatggcct gccggtggtg ctgtcgaact gctcgaacaa ttacgggccg
    24781 ttccacttcc ccgagaagct gatcccgttg accatcctca acgcgctcga gggcaagccg
    24841 ctgccggtct acggcaaggg cgagaatatc cgcgactggc tgtatgtcga cgatcacgcc
    24901 aaggcgctgg cgaccatcgc caccaccggc aaggtcggcc agagctacaa tgtcggcggc
    24961 cgcaacgagc ggaccaacct gcaggtggtc gagacgatct gcgacctgct cgaccagcgc
    25021 attccgctgg ccgacggtcg caagcgccgc gaactgatca ccttcgtcac cgatcgcccc
    25081 ggccatgacc gccgctacgc gatcgacgcg accaagctcg agaccgagct gggctggaag
    25141 gctgaggaga atttcgacac cggcatcgcc gcgacgatcg actggtatct ggcgaacgag
    25201 tggtggtggg gcccgatccg ctccggcaaa tatgccggcg agcggctggg gcagaccgcc
    25261 tgatgcgtat cctcgtcacc gggcatgacg gccaggtcgc ccagtcgctg gccgagcagg
    25321 cggtgggcca cgagctggtc ttcaccacct accccgaatt cgatctctcc aagccggaga
    25381 cgatcgaggc cggtgtggcg cgggtgcacc cggacctgat cgtctccgcc gccgcctaca
    25441 cggcggtcga caaggcggaa agcgaacccg agctggcgat ggcgatcaac ggcgacggtc
    25501 ccggcgtgct ggcgcgcgcg ggcgcgaaga tcggcgcgcc gatcatccac ctgtcgaccg
    25561 attatgtgtt cgacggcagt ctcgaccgcc cttggcgcga ggacgatccc accggcccgc
    25621 tcggcgtcta tggcgcgacc aagctggccg gcgagcaggc ggtgcaggcc tcgggtgcca
    25681 ccaacgccgt gatccggctg gcctgggtct acagcccgtt cggcaacaat ttcgtcaaga
    25741 cgatgctccg cctcgccgag acgcgcgacg cgctgaacgt cgtggaggac cagtggggct
    25801 gccccagttc ggcgctggac atcgcgaccg cgatcctgac ggtggtcggg cactggcagc
    25861 aggacggcgc gacgagcggc ctctaccatt tcgccggcac cggcgagacc aactgggccg
    25921 acttcgcatc gacgatcttc gccgagagcg ccaagcgcgg tggcccctcg gccaccgtca
    25981 ccggcattcc cagctcgggc tatccgactc cggccacgcg cccggccaat tcgcggctgg
    26041 actgcacccg cttcgcggag accttcggct accgggcgcc tgcctggcag gattcgctga
    26101 acgtcgtact ggatcgcctg ctcggctgat ccgaaacggg gggcctcagc gccccccgcc
    26161 atgctcccgt tcgcgcgccg gcaatgcctc tagcaccgcg cgctttccct taggactcag
    26221 ctcgctccag ccggcgattt ccttgggcga ccgccagcac cccaggcaca gccggatctc
    26281 catgtcgagg cggcagacct tgcgacaggg cgattccggc ggtgcggcgg caaagcgcga
    26341 gaacagcccc atcagcgctt gaagttcagc cccgtcttgc gggcgaactt ggcgaggccg
    26401 ttgatcaccg gggtcggcgc atagtcgcgg atcaggccct tcacccggtg cagcgcggtg
    26461 cgcttgtcgt gcgccgagac ggcccttcca acgcacgaag ttcgaatagc cgcgaccctc
    26521 ggtatcctcc tctgcgctgt agtagtagag tgcgagcgag ttgcggcgga tgttcggcgg
    26581 cgtctgcagc gggaagggct ggccgtgcca cgacttgccc gagacgcgga agatcgcgag
    26641 gcgattgaac ttgggcgtga tgctggaaac gcacctggtc gcatcctcgt cccacagctc
    26701 caggtcgccg ccccattcct cctgccagtc tggcgtgcag taatagatgc agttgatctg
    26761 ctggctgagc ttcttgttgg ggtggcgcga ggcatcgatg tggagcatca gccgcccgcc
    26821 cgagccggtc gagtgcaggc cgcagccata atggttggga tccggcagca ggtgcttgtg
    26881 gccgctcagc cggtcgagga agttgcagaa gatgcccgac tgaaactgca tcatcatcag
    26941 gcggacgagc ggcggaaact gctcctcgtc cgaggtcgtc acctttcgat cttgcgatca
    27001 ccgctgtgcg cgctatcgcc cggcccttcc aggcgccagt tgacgtcgtc cagcttcggg
    27061 aaggcatccc cgagccgccg cgccacgtcg tcgggcagga aattgtcgat cgcgacatgc
    27121 tcatagggct cggcgttcag gaagcgatca tgatattcgt ccgcgagcgc atatagcttc
    27181 tcgcgcgtga agaagaagaa gtccgaagta tctgcaccga ccgacatgca atcccccccg
    27241 aagaaacgga cgcagcgatc ataaacgatt caccgcaatc gcgtaacccg tcttgcacag
    27301 caccgtaaca cttagcgatc ccttatccga accacgatcg gcttgaccag gcggataccg
    27361 aattcgcgga agcgccggat cggcgtgcgc accgcatggt cccacagaat cgcgccggcc
    27421 gccaccggcc gtgcggcgac atcgctgcgg atcttgaaca tattgatgat gtcgatgtcc
    27481 gaaaccagct tgcccttgat ccggttggtt acattctcgc cgtgcaccac ctgcagccat
    27541 agcggcttgc tcggcacctg gcggatcgtc cacttctcgc ccagctcgtg gtgcggcttg
    27601 gcccagatcg tctcgatccc ggccacgtct ttctcgacca gcgaggtgaa cgggctgctg
    27661 tgatcgctgg cggtgtagag ttgcccgccc cgcatcgcga tgccgtgggg gaagttcagc
    27721 acggtctgcg ccggcgcttc cttggcggcg tcctgcaccc gcgcgacgaa atcgctcgac
    27781 accgcatcat cattgtccag ccgcgtggtg acgatcagcg tctcgcccgc cgtcgcgagt
    27841 gcccgcacgt cctcggcgat catcgccttg tcgaacatcg ccacatagcg tggggtaaaa
    27901 ttgaagatct ggcgatcgcg ctcgatccgc tcgcggaatt caaccggcgt atccttgtcg
    27961 aaatagatca gccagtggaa gttgcgctcg gtctggcccg cgatgctcgg caggcagaac
    28021 tgctcgaaca ggccgaaacg gcgttccagc cagcccggcg agttgcgaat cgccacctcg
    28081 cgtcccgggc tggcgatgtt gaagcgagtc aggatcacgt ggagcatggg gttgatcagc
    28141 ccttgtttgc ggaaggaatg gcgcggggca cggcgaccgg gcatgccagg aaccgggagc
    28201 ggcgcttcgc gacatggcgg agcttcgccc tgaatggcac gcgctgcacg gctgctagcc
    28261 ccctttattg ccgttcacct gcttcggtta agggatattc cggagcccgg caaccggcga
    28321 ttgctgcgct gcgcaatgaa cggcgccgcc gcgtggtggc caagggcgcg ccaatccaca
    28381 cctgccgggc cggcgatcgc gcgcccaaag cgccgccaac gcattcgcaa ggcttgcgaa
    28441 ataaatggct tgcccctacc cgagcccggt gtcgccccct cgtcccgaca gcatcgccac
    28501 cggcctggcg cttcgcctgt tcgcgatcgc ctgcatgtcg accatgtcgg cgctcatcaa
    28561 gatgtccgaa ctgcgcggcg cctcgctgat cgagacgatg tttcaccgcc agctctgggc
    28621 ggtgcccttg gtcaccctgt gggtcacgct ggggccgggc ctcaagtcgc tcaggaccgc
    28681 gcggttcggc gcgcatgtct ggcgcaccgc ggtgggactt accggcatga tcttcacctt
    28741 cggcgcggtg atcctgctgc cgctcgccga agcgcagacc ttccagttca ccgtccccat
    28801 cttcgcgacg ctgctcggcg cgctgatcct aggcgaaccg accggctggc accgctggag
    28861 cgcggtgatc ctcgggttcg tcggcgtgct tatcgtcgtc cagccggggc acgaggcgat
    28921 cccggtgttc ggtgcgttcg tgggcctgat ggcggcgctg ttcgtcgcca tcgtcgcgat
    28981 cacgctccgc cagatcggga agaccgaaag cgccggcacc acggtgttct ggttctcgct
    29041 gttgtcggtg ccggtgctgg gcgcaatcta tgccttccac tacaagcccc atgatgccga
    29101 gacctgggcc atcctgatcg ccacgggcct ggtcggcggc gtcggccagc tcgcgctgac
    29161 cggggcgatg cgcttcgctc ccgtgtcggc agtggtgccg atggactatt cggggctgct
    29221 ctgggcgacg ctctatggct ggctgctgtt cggcgtgctg ccgacctttt ccacctggct
    29281 cggcgcgccg gtgatcatcg ccagcggcct gtacatcgtc tatcgcgagc agaagctggc
    29341 gcgcggccag gctagctacg ccgaaacgcc actatgaggt tgttggcggg catcgccacc
    29401 cgccgctcga acaccagccc ctgcgcttcc gccgccgcca cgacatcgcc cagcaaccgc
    29461 aggccccagg cgg
//
