LOCUS       BGC0000765             22198 bp    DNA     linear   BCT 01-FEB-2007
DEFINITION  Lactobacillus johnsonii strain ATCC 33200 exopolysaccharide
            biosynthesis gene cluster, complete sequence.
ACCESSION   BGC0000765
VERSION     BGC0000765
KEYWORDS    .
SOURCE      Lactobacillus johnsonii
  ORGANISM  Lactobacillus johnsonii
            Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
            Lactobacillus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:10:25
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..22198
                     /db_xref="ATCC:33200"
                     /db_xref="taxon:33959"
                     /mol_type="genomic DNA"
                     /organism="Lactobacillus johnsonii"
                     /strain="ATCC 33200"
                     /type_material="type strain of Lactobacillus johnsonii"
     subregion       1..22198
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000765"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..22198
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            458..1462
                     /locus_tag="ATCC33200LJ0001"
     CDS             458..1462
                     /codon_start=1
                     /locus_tag="ATCC33200LJ0001"
                     /product="eps transcriptional regulator"
                     /protein_id="ABM21381.1"
                     /transl_table=11
                     /translation="MDHKNSDNELRHRSHHHRHHRRKKFWRIFWIVLGVFLAVDIIAVI
                     IAWHNIHVATNNMYNPMSNEISDRKVSDKLKDKKPMSLLLLGTDTGEFGRSYKGRTDTI
                     MMMVINPKTNKTTVVSLPRDMKVNLPDYPDYSPAKINAAYTYGGVDETVKTIKKYFNVP
                     TDSYVMVNMGGLEKAIDQVGGVTVKSPLTFDYEGYHFTKGVTYHMNGKKALAFSRMRYD
                     DPKGDYGRQERQRLVIMALLKSSISYKTVVNQAFLNSISKQTMTNLTFDNMVALAQNYR
                     HATDNITSDHAQGQGDWENGVAYESVSQAECQRISNKLRAALGLKPETLKTGE"
     misc_feature    458..18083
                     /note="exopolysaccharide biosynthesis gene cluster"
     gene            1469..2332
                     /locus_tag="ATCC33200LJ0002"
     CDS             1469..2332
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 49.7; E-value: 3.4e-15)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC33200LJ0002"
                     /note="wzz-like protein"
                     /product="polymerization and chain length determination
                     protein"
                     /protein_id="ABM21382.1"
                     /transl_table=11
                     /translation="MENSTKTENTIDLRRLWMLLRAHIWAIIAWAVGLGAVGFVLAAFV
                     VEPKYTSTTQILVNQKRNTTDAGQAFNAQQADVQLINTYKDIVTSPVILKDASKWLKNP
                     TEVVKPAKKAQYKTLADGTKKLVSPAEPAVVRRAGRGYNVSAKEMQKAVSVSTQQQSQV
                     FTISAKSNDPEKAQAIANAVAKTFKNKIKSIMNVNNVTIVSPAARGIKTFPKTTLFTLA
                     GIVLGLIISVALIVLRDSFNTTVRDDDYLTKELGLTNLGHVSHFHLSNDFSINKKNNDS
                     GKKKRV"
     gene            2343..3098
                     /locus_tag="ATCC33200LJ0003"
     CDS             2343..3098
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 221.9; E-value: 2.3e-67)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC33200LJ0003"
                     /product="polymerization and chain length determination
                     protein"
                     /protein_id="ABM21383.1"
                     /transl_table=11
                     /translation="MGLFNRRRKRGTDETMQYGAKLITVAKPQNPVSEQFRTVKTNIDF
                     TSVDHQIKALAFTSANISEGKSTVTVNVAVTMAQAGKKVLLIDADLHRPTLHQTFDIPN
                     RVGLTTILTSHSNEVDMANIVKEDIIPNLSVMPAGPIPPNPAQLLGSNRMRAFLNMVKE
                     HYDLVILDLAPVLEVSDTQILAGEMDGVVLVVRQGVTQKAGVERAIEMLNLTKTHVLGY
                     VMNDVKTGPDGYGYGYGYGYSQEKDGETK"
     gene            3105..3875
                     /locus_tag="ATCC33200LJ0004"
     CDS             3105..3875
                     /codon_start=1
                     /locus_tag="ATCC33200LJ0004"
                     /product="polymerization and chain length determination
                     protein"
                     /protein_id="ABM21384.1"
                     /transl_table=11
                     /translation="MVLVDIHAHILPGIDDGSPDLESSLGLAEAAVADGITHALMTPHT
                     LNGKYLNHKEDIIKETASFQKELEQHNIPLTVFPSQEVRLNGNLPQALDDDDILFCDED
                     GRYMLLEFPSEDVPTYAKDMTFKLLGRGITPIIVHPERNSGILAHPEKLQEFIEQGCLT
                     HITASSYVGVFGKEIEKLADQFVEAGQVATFASDAHTLPKRESRMHDAYEKLEKTQGLD
                     VANSFKQNARNIINSDNVNLNWKPLKKKKRFWIF"
     gene            3903..4562
                     /locus_tag="ATCC33200LJ0005"
     CDS             3903..4562
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 323.8; E-value:
                     3.1e-98)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC33200LJ0005"
                     /product="phospho-glycosyltransferase"
                     /protein_id="ABM21385.1"
                     /sec_met_domain="Bac_transf (E-value: 2.3e-75, bitscore:
                     242.0, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMAQEVKRVKLDPSKVKGRVGYRAVKRGFDILASGLALILLSPLF
                     LVLIVLIKKEDGGPAFYSQERIGKNEKPFKMWKFRSMIVNADKMVKQLEEQNEIDGAMF
                     KIKDDPRVTKIGHVIRKYSLDELPQLWNVLKGDMSLVGPRPPLPMEVADYTDYDKLRLT
                     VTPGCTGLWQVTKRNDADFDEMVELDLEYINKSSLWFDFKILLKTVGVVIHPNSAY"
     gene            4581..5030
                     /locus_tag="ATCC33200LJ0006"
     CDS             4581..5030
                     /codon_start=1
                     /locus_tag="ATCC33200LJ0006"
                     /product="glycosyltransferase"
                     /protein_id="ABM21386.1"
                     /transl_table=11
                     /translation="MKVCLVGSSGGHLTHLYMLKPFWQNKDRFWVTFDKEDARSKLKSE
                     KMYGCYYPTNRNLKNLIRNTFLAIKVLRKERPDVIISSGAAVAVPFFYIGKLMGAKTVY
                     IEVFDRYDKPTITGKLVYPITDKFIVEWEEMKKVYPKAINLGSIF"
     gene            5040..5540
                     /locus_tag="ATCC33200LJ0007"
     CDS             5040..5540
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC33200LJ0007"
                     /product="glycosyltransferase"
                     /protein_id="ABM21387.1"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 2.6e-37,
                     bitscore: 118.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFVTVGTHEQPFNRLVKKIDDLVAEGTIKEKVVIQTGFSTYKPV
                     HCEGHKMMSFEEMQNTLKDARIVITHGGPSSFIEALQFGKVPIVVPRQEKYHEHVNNHQ
                     VDFTELIEKRMNNIIPVYDVNKLAETIKNYDEIVKTKNVGESSNNRKFNQSLEHIINEL
                     VGK"
     gene            5541..6266
                     /locus_tag="ATCC33200LJ0008"
     CDS             5541..6266
                     /codon_start=1
                     /locus_tag="ATCC33200LJ0008"
                     /product="glycosyltransferase"
                     /protein_id="ABM21388.1"
                     /transl_table=11
                     /translation="MTIPKVIHYCWFGNNPKPKVIQDCIESWKKYCPDYEIKEWNESNY
                     DVNKTKYTQLAYKSKKYAFLTDYVRLDALYNEGGVYMDTDVKLIKSIDDLVKKGNFMSF
                     EKVGRVNTGVGFASEKGTSILKENLDYYNTHTFVDKNNNFDPEICVKITTQLLEKHGLD
                     YKRNEQQEVENFTIYPSDYFSPKKMGTEKITITSNTYGIHLYASSWYKGSKLSKKIKYH
                     LIPLKEFVKYKILKRKLYE"
     gene            6259..7164
                     /locus_tag="ATCC33200LJ0009"
     CDS             6259..7164
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC33200LJ0009"
                     /product="glycosyltransferase"
                     /protein_id="ABM21389.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.5e-22,
                     bitscore: 70.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKVAYKEQISIITPVFNRLKELTRLYKSLRTQNNNNFIWIIVDD
                     GSEKTINEIVDIWKKESKFKIDLIVQSNQGKMHAYKNAMKRLNTPWSLVVDSDDTVSEE
                     MIDILYKTILSINSDNDCGVVFPRKLGADSNGTSLWKQLPNKVNIIDLRYQYNIPESTI
                     FIKTNELKKAFNSLQLPDEKFISEEILYNKLMEQGKFVVRDELFYFGDYQEDGLTKHLF
                     ELWLKNPKSTIMLLNSRYRAMNSFPWKKRLIGQWKTNINLTAFALATNRSIKSVSPDLI
                     ESIFLFLPALVLKEKRFKIE"
     gene            7178..8200
                     /locus_tag="ATCC33200LJ0010"
     CDS             7178..8200
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC33200LJ0010"
                     /product="glycosyltransferase"
                     /protein_id="ABM21390.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6e-31, bitscore:
                     97.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIPVHNSSNFVDTIYNNISSQIYTNFEVLIIDDHSRDNTKEELK
                     EKFKNAKFKYRILSSNGNGVSAARNMGIEKSQGRYVAFIDDDDEIVPDYLEILHNHVAN
                     DNIPIALGNYSEITQDKETPFKFKNAGIFDNEWVINKLIPQTIFPLEGEQSIWLPVWRT
                     IIKRDIIISNNIKFDEKISQAEDFLFMIELLLKAERISIISGKSIYFYNRRQSSAMNKY
                     IENDIEKQKYFHKRFYELLNKNDLYNLYRKRYLSNRVKMYSTLISNATRASNKKVGIQE
                     IKKSRELFLKDDYVNSTSLKSLYNSKSIQFAIYLLRHNKVVLLYSIYRLKEKKRLNQFN
                     "
     gene            8223..9251
                     /locus_tag="ATCC33200LJ0011"
     CDS             8223..9251
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ATCC33200LJ0011"
                     /product="glycosyltransferase"
                     /protein_id="ABM21391.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 8.4e-39,
                     bitscore: 123.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPDITVIVPIYNVEKYIRKCLDSLKRQTYKNFEVWAIDDGSPDN
                     SKKIVQEYADKDPRFKSILKENGGYGSVLEYGIKNTKTKYFLVCDPDDWLTDDALEKLH
                     NFAKNSNLDVTVGDKYNIYSEDNKKVYIPSFKKELNVKPRVAYDTAEKKDRFIFSEVSP
                     HAKLFKTSIAKNIDFPHKISYTDTILYVLSIANAKRVGYLDEALAYYLIDRPGNTMTAK
                     TEAKIRDTIKIWHSIYNQLINGFELNQIETYIYFLYYEMKIILITESQLPSMSKYHTEI
                     LKIMRIMQRYNKILAKYVNNKVVPYNTNSMTGRLIFKGFMNKATYKWVERLYVKLERKR
                     EA"
     gene            9253..10359
                     /locus_tag="ATCC33200LJ0012"
     CDS             9253..10359
                     /codon_start=1
                     /locus_tag="ATCC33200LJ0012"
                     /product="UDP-galactopyranose mutase"
                     /protein_id="ABM21392.1"
                     /transl_table=11
                     /translation="MTNYLIVGSGLFGAVFAHEVAKRGNKVTVIEKRNHLAGNIYTKEV
                     DGIQVHQYGAHIFHTSDKKVWDYVQQFAEFNRYTNSPVANYYGKMYNLPFNMNTFSEMW
                     GVRTPQEAMDKINEQRQEMAGKDPQNLEEQAISLIGRDIYEKLIKGYTEKQWGRKATEL
                     PAFIIKRLPVRLTYDNNYFNDDYQGIPKGGYTQIVEKMLDNENIEVKLNTDFFDKKDEY
                     LKNFDKIVYTGMIDKFFDYKLGELEYRSLRFETEEKDVDNYQGNAVINYTDAETPYTRV
                     IEHKHFEFGKGDKGKTIVTREYPANWKRGDEPYYPVNNERNNNLYKQYKGLAEKQNKVI
                     FGGRLGQYKYYNMDQVIAEALRMSNSVE"
     gene            10365..11537
                     /locus_tag="ATCC33200LJ0013"
     CDS             10365..11537
                     /codon_start=1
                     /locus_tag="ATCC33200LJ0013"
                     /note="wzy-like protein"
                     /product="polymerization and export protein"
                     /protein_id="ABM21393.1"
                     /transl_table=11
                     /translation="MDLKKKELTNFFCIVYFIWGLFQQIQNTVNIKFKFEESIGQILNV
                     FLLVSMFFLLLLVMKNQNFEVRIWNIISLILFFGLIIYLSKNQNFTFIATYALILMAGN
                     FYFEDILKTFLIFTAIILISTIFLFKLGRIPNAIVVGQYLRVRSSLGFGYYTYSAQLLF
                     YFTLAYLVFRKQKITYVELIILEAANYFIYYSTNTRNPYILSTLFILFVLVDKIFKFKL
                     DILRFKLVKFIILFAFPICFIVLNVLMFWIPKSLFYTLNEALSGRLALNISGLQMWGVK
                     LLGQKIDFEAINVNGMATQYYNFVDSSYFQTLLVSGCLFFIIIMILLIYICNKSIKEHE
                     QYLGIALFLIAIHSMFDPQLLLPWYSPFCLLLGQFFAVHDSSIFEKTIQE"
     gene            11547..12973
                     /locus_tag="ATCC33200LJ0014"
                     /note="polymerization and export, wzx-like protein,
                     flippase; contains frameshift"
     gene            12987..14003
                     /locus_tag="ATCC33200LJ0016"
     CDS             12987..14003
                     /codon_start=1
                     /locus_tag="ATCC33200LJ0016"
                     /product="membrane protein"
                     /protein_id="ABM21394.1"
                     /transl_table=11
                     /translation="MSNRKHRNYGLDLVKILACILVLCLHSLVPTSPVVKNSLLNLSVY
                     YAGAIAIPIFFMASSYFVLNKRMMSYSYVMRRVGEILFIIIGWVLIYSIVHLCIKHNFI
                     FLEELKGTAFVGIPNQHFYHFWFFWALIIMLLLSPLLWYLLQKSFVGYLILTSIVTLIC
                     IGIDISMHFGNSSNIRNIPQIFRLYLYIEYYLLGGLIGNTNFEKIKNFCKQHFVMTCIV
                     ASFLYVGVIAYSIWNRNIIHWFYAEANYGNALIIFTSVLILIIFSISSPPNKSTIEFII
                     PATMGIYMLHPFFIGKLMKIHILYNYPIFMIPVLFILCLIIVEIALRIPIINRFFKL"
     misc_feature    14346..16271
                     /note="transposase fragments"
     gene            16758..18083
                     /locus_tag="ATCC33200LJ0022"
     CDS             16758..18083
                     /codon_start=1
                     /locus_tag="ATCC33200LJ0022"
                     /product="hypothetical protein"
                     /protein_id="ABM21395.1"
                     /transl_table=11
                     /translation="MNINEWFEDPKVFEKSKREYAHFDLRTDLAKCKKYITNSKNIERH
                     GFYPFIKYDLEYHKYNRAEGRKTKKRTICYASHIDSCIFQYYSFLINKKYNARLKQDGI
                     YEVPIAYRTDLHTDTIAEFRKMHQFMIQHPSSYVMIGDFTSFFDKIDHQYLKERLCDLL
                     QVDKLNSDYYAIFKRITKYDYWDLTDLYRLNNLNPKKRKDKIKINSKVRILSQSDYKKY
                     RSHIRQHQDNKGIPQGSSISACLANVYMLEIDRLINEFVVARGGIYRKYSDDFIIILPM
                     DTSSTDDIEKIILKFGAFKDKGILELQPEKTQVYKLQDHSVVNIGHLFTPSLNEKNKTI
                     NFIGFTFDGNAIKIREKTTSKYYYRMHHKAKGVAHQYYRNKYYKGADKLYQLYSPNGQY
                     GKGNYFTYLSRVQNAFPNQSIMISEDRIMTNIRLTLKKNRWG"
ORIGIN
        1 ccaaatctag caccaaagaa aataattgac ttagttgcaa ctaaagaaga cttaaaaggt
       61 aagcgaaaat agttgcttta tacggataaa gtttctattg tagaggcgag agtgtaataa
      121 gagacagaag agttgaaaga tgaaaatttc aatttgaggg gcgattatgc atgtccttac
      181 tgctacattg gtgaaaccaa ctaacaaaag gcaattgaag agttaggtgt tcaagataag
      241 attgaatatg acttgaatgc tttttaaatt gatttagatg cacctaagtc aactaagcaa
      301 actaatgcag tcctttcaat gtgaaggtgg ttagagcatg ttttgattca ataaatgtgt
      361 tttttatgct aattgtgaat tttctatgag ttttcatata ttttttgtat aataactttt
      421 agtgttacta aaaagcaaaa aataaaagag gaataaaatg gatcataaga atagtgataa
      481 tgaattaaga catcgctcac atcatcaccg gcatcatcga cgtaaaaagt tttggcgtat
      541 cttttggatt gtattaggtg tcttcctagc agtagacatc attgcggtta ttatcgcttg
      601 gcacaatatc catgttgcca ctaacaatat gtataatccg atgagtaatg aaattagtga
      661 tcggaaggtt agcgacaaac tgaaagataa gaagccaatg agcctgcttt tattgggaac
      721 agatacaggt gaatttggac gttcttacaa ggggagaaca gataccatta tgatgatggt
      781 tatcaatcct aagaccaata agacaacagt tgtcagcttg cctcgagata tgaaagttaa
      841 cttaccggat tatccagact attcaccagc taagattaat gcagcctata cttatggtgg
      901 tgtagatgaa actgttaaaa cgatcaagaa gtactttaat gttccaactg attcttatgt
      961 catggtaaac atgggagggc tcgagaaggc aattgatcaa gttggaggag tgacagttaa
     1021 gtcgccatta acgtttgatt atgaaggcta tcacttcact aagggcgtaa cttatcacat
     1081 gaatgggaag aaagctttag cattcagtag aatgcgttat gatgacccaa aaggagatta
     1141 tgggcgtcaa gagagacaaa gacttgtaat tatggcatta ttaaagagtt ccatttctta
     1201 caagacagtc gttaaccaag cattcttgaa ttcaatctct aagcaaacta tgactaactt
     1261 aacgtttgat aatatggttg cgttagctca gaattatcgt catgcaactg ataatatcac
     1321 aagtgatcac gctcaaggac aaggcgattg ggagaatggc gttgcctatg agtcagttag
     1381 tcaagcagaa tgtcaaagaa ttagtaataa gttacgtgct gccttagggc ttaagccgga
     1441 aaccttaaag acaggagaat aggaaaaagt ggaaaacagt acaaaaactg aaaatacaat
     1501 cgatttacgt agattatgga tgcttcttcg agcacatatt tgggcaatta tcgcctgggc
     1561 cgttggttta ggagcagttg gatttgtctt agctgctttt gtcgttgagc caaagtatac
     1621 ttcaacaact cagattttgg ttaaccaaaa aagaaatacg acggatgctg gtcaagcatt
     1681 caatgctcaa caagctgatg tccagttaat taatacttat aaggatattg ttactagtcc
     1741 agttatttta aaagatgctt ctaagtggct aaaaaatcct actgaagttg taaagccagc
     1801 taaaaaagct cagtacaaga ctttagctga tggtactaaa aaacttgtta gtccagctga
     1861 accagctgtt gtaagaagag cgggacgtgg ctacaacgtt agtgctaaag aaatgcaaaa
     1921 agcagtgtca gtaagtacac aacaacaatc tcaagtattt acaattagtg ctaagagtaa
     1981 tgatccagaa aaagcgcaag caattgcaaa tgcggttgct aaaactttta agaataaaat
     2041 taagagcatt atgaatgtta ataatgtaac aattgtgtca ccagctgctc gtggtattaa
     2101 gacattccct aagactacac tatttactct cgcgggtatt gtgcttggat taattattag
     2161 cgttgcttta attgtcttac gtgattcatt taatactaca gtcagagatg atgactactt
     2221 gacgaaggaa ttaggtttaa ccaatttagg tcatgtatct cacttccact tatctaatga
     2281 ttttagtatc aataagaaga acaatgattc tggtaaaaag aagcgtgtat aggagagtat
     2341 aaatgggatt gtttaataga cgtagaaaac gtggtacaga tgaaaccatg caatatggtg
     2401 ctaagttaat tactgtagca aaaccgcaaa atccagtaag tgaacagttt agaacagtga
     2461 agactaatat tgactttact agtgttgatc atcaaatcaa agctttagct tttacatcag
     2521 ctaatattag tgaaggaaag tcaactgtaa cagtgaatgt ggcggttaca atggctcaag
     2581 caggtaaaaa agtattattg attgatgccg atttgcacag accaacatta caccaaacat
     2641 tcgacattcc aaatcgagta ggattgacta caattttaac ttcacattct aatgaagttg
     2701 atatggcaaa tattgttaaa gaagatatta ttcctaatct ttcagtaatg cctgctggtc
     2761 ctattccacc taatccagct caattattgg gttctaatag aatgcgtgcc tttctaaaca
     2821 tggttaagga acactatgat ttggtaattt tggatttagc gccggtctta gaagtttcag
     2881 atacccaaat tttagctggt gaaatggatg gagtagtttt agttgtacgt caaggagtta
     2941 cgcagaaggc tggagttgag cgtgctattg aaatgcttaa cttaactaag acacatgttt
     3001 tagggtatgt aatgaatgac gtgaaaactg gtccagatgg ctatggatac ggctatggct
     3061 atggatacag tcaagaaaaa gatggagaaa cgaagtaata aataatggta ttagttgaca
     3121 ttcacgcaca tatattgcca ggaattgatg atggttctcc tgatttggaa tcttcattag
     3181 gtctagcaga agctgcagta gccgatggaa ttactcatgc attaatgacc ccacatactt
     3241 taaatggaaa atatttaaat cataaagagg atatcattaa agagacagct agttttcaaa
     3301 aggaattaga acagcacaat attcctttga ctgtctttcc aagtcaagaa gttcgtctaa
     3361 atggtaattt accgcaagct ttagatgatg atgatatctt attttgtgat gaagatggca
     3421 gatatatgct attagaattt ccaagtgaag atgtaccaac ttatgccaaa gatatgactt
     3481 ttaaattgtt aggacggggg attaccccaa tcattgttca tccagaaagg aattctggta
     3541 tcttggctca tccagaaaaa ttacaagagt ttattgagca aggctgttta acgcacataa
     3601 ctgctagttc gtatgtggga gtctttggaa aagagatcga aaaattagct gatcaatttg
     3661 tagaagcggg tcaagtagcc acttttgctt cagatgcaca tacgttgcca aaacgtgaaa
     3721 gtcgaatgca tgacgcttat gagaagttag aaaaaacgca aggattggat gttgctaata
     3781 gctttaagca gaatgcacga aacattatta attctgataa tgttaattta aattggaaac
     3841 ctttaaagaa aaagaaacgg ttttggatat tttaagttta ttgttggggg atagagtttt
     3901 aaatgatggc acaagaggtt aaaagggtaa aactagatcc gtcaaaagtt aagggacgtg
     3961 taggataccg tgctgtaaaa cgtggctttg atattttagc tagtggattg gctctgatat
     4021 tattgtctcc attattttta gttttaattg tcttaattaa aaaggaagat ggtggaccag
     4081 ctttctattc acaagaacga atcggtaaaa atgagaaacc atttaaaatg tggaagtttc
     4141 gttcaatgat tgtgaatgcc gataaaatgg taaaacagtt agaagaacaa aatgaaattg
     4201 acggggcaat gtttaagatt aaagatgatc ctcgtgtaac taaaattggt catgtaatta
     4261 gaaaatatag tcttgatgaa ttacctcagc tttggaacgt gttaaaaggt gatatgtctt
     4321 tagtaggtcc acgtccacct ctaccaatgg aagtggctga ttatactgac tatgataaat
     4381 tgcgtttaac tgttacacca ggttgtacag gactttggca ggtaacaaaa cgtaatgatg
     4441 cagactttga tgaaatggta gaattagacc ttgaatatat caataagagt agtttgtggt
     4501 ttgattttaa gattttatta aagactgttg gtgttgttat tcatccgaat agtgcgtatt
     4561 aaggagagaa agaaaaaagt atgaaagttt gtttagttgg ttctagcggt ggtcacttaa
     4621 ctcatcttta tatgttaaag ccattttggc aaaataagga tagattctgg gttacttttg
     4681 ataaagaaga tgcaagaagt aagctgaaat ctgaaaagat gtatggatgt tactatccca
     4741 ctaaccgtaa tctaaaaaac ttgattcgta atactttttt agcaattaaa gtgctccgta
     4801 aagaacgtcc tgatgtaatt atttctagtg gggctgcagt agcagttcca tttttttata
     4861 tcggaaaatt aatgggtgct aagactgttt acattgaagt atttgatcgc tatgataaac
     4921 ctacaattac tggtaaattg gtatatccaa taacagataa gtttatcgtt gaatgggaag
     4981 aaatgaagaa agtttatcct aaggcaatta atttaggaag tattttttag ggtgataaga
     5041 tgatttttgt tactgtaggt actcatgagc agccttttaa ccgtttggtg aaaaaaatag
     5101 atgatttggt tgctgaaggt acaattaagg aaaaagtggt tattcagact ggttttagta
     5161 catataaacc agtacattgc gaaggccaca aaatgatgtc ttttgaagaa atgcaaaata
     5221 ctttgaaaga tgcgcgtatt gttattacgc atggtggacc ttcaagtttt attgaagcat
     5281 tacaatttgg aaaagttcca attgtggttc ctagacaaga aaaatatcat gagcatgtta
     5341 acaatcacca agttgacttc accgaattaa ttgaaaaaag aatgaataat ataattcctg
     5401 tttatgatgt aaataaactt gctgaaacaa ttaaaaacta tgatgaaatt gtcaaaacaa
     5461 aaaatgttgg cgaaagtagt aataatagga aatttaatca aagcttggaa catattatta
     5521 atgaattagt ggggaagtaa atgactatac caaaagtaat acattattgt tggtttggaa
     5581 ataatccaaa acctaaagta attcaagatt gtatagaatc ttggaaaaaa tattgtcccg
     5641 attacgagat aaaagaatgg aacgaatcaa attatgatgt aaataaaact aagtatactc
     5701 agttagctta taaaagtaaa aagtatgctt tcttaaccga ttatgttcgt ttagatgccc
     5761 tttataatga gggtggtgtc tatatggata ccgatgtgaa attgattaag tcaattgatg
     5821 atcttgttaa aaagggtaat ttcatgtctt ttgaaaaagt aggtcgggtt aatacaggtg
     5881 tgggatttgc tagtgaaaaa ggcacatcta tccttaaaga aaatttagat tattataata
     5941 cacatacatt tgtggataaa aataataatt ttgatcctga aatttgtgta aaaataacta
     6001 cacaattgtt ggaaaaacat ggactagatt ataagcgtaa tgaacagcaa gaagtagaga
     6061 attttactat ttacccatca gattatttct ctcctaaaaa aatgggaaca gaaaaaatta
     6121 caattacttc aaatacttac ggtatacatt tgtatgcttc tagttggtat aaaggatcaa
     6181 aattgtccaa aaaaattaag tatcatctaa ttccgcttaa agaatttgtg aaatataaaa
     6241 ttttgaaaag aaaattatat gaataaggta gcatataaag aacaaatatc tattattacc
     6301 cctgttttta atagattaaa agaattaact agactatata aatcgttacg cacgcaaaat
     6361 aataataatt ttatatggat tattgtagat gatggttctg agaaaactat taatgagatt
     6421 gtagatattt ggaaaaaaga atcaaaattt aagattgatt tgatcgtcca gtctaatcaa
     6481 ggaaaaatgc atgcctataa aaatgcaatg aaacgtttga atacaccatg gtcgttagtc
     6541 gtagatagtg atgatactgt atcagaagaa atgatagata ttttatataa aacaatatta
     6601 tctattaatt ctgataatga ttgtggtgta gttttcccaa gaaaattagg tgctgattcg
     6661 aatggaacat ctctttggaa acaattacca aataaagtta atattataga tttgagatat
     6721 caatataata ttcccgaatc tactattttt ataaaaacta atgaattaaa aaaggcattt
     6781 aactccttac aattacctga tgaaaaattt attagtgaag aaatacttta caataaatta
     6841 atggaacaag gtaaatttgt tgtaagagat gaactatttt attttggtga ttatcaagag
     6901 gatggactaa caaaacatct ttttgaatta tggttaaaaa atcctaaaag taccattatg
     6961 ttgttgaatt caagatatcg cgcaatgaat tcatttcctt ggaaaaagcg attgataggt
     7021 caatggaaaa caaatattaa tttaactgct tttgcacttg caactaacag atcaattaaa
     7081 agtgtttcac cagatttaat agaaagtatt tttttatttt taccagcgtt ggttttgaag
     7141 gaaaagagat tcaaaattga ataactatga gattagtttg ataatcccag ttcataattc
     7201 atctaacttt gttgatacaa tctacaataa tatttcttcg caaatataca caaatttcga
     7261 agtacttata atagatgatc attcgcggga taatacgaaa gaagaattaa aagagaaatt
     7321 taaaaatgca aaatttaaat atagaatttt atcgtcaaat ggtaatggag tttctgcagc
     7381 aagaaatatg ggaatagaaa aatctcaagg aagatacgtt gcttttatag atgatgatga
     7441 tgaaattgtt cccgattatt tagaaatttt gcataatcat gtagctaatg ataatattcc
     7501 gattgcacta ggtaattata gtgaaattac acaagataaa gaaacacctt ttaaatttaa
     7561 aaatgctggt atttttgata atgaatgggt tataaataaa ttaataccac aaaccatatt
     7621 tccgttagaa ggagaacaat ctatttggtt accggtatgg cgtaccataa tcaaacgaga
     7681 tattattata agtaataata taaaatttga tgagaagata tcacaagcag aagatttctt
     7741 atttatgatt gagcttttat taaaagctga acgtatatca ataatttcag ggaaatctat
     7801 atatttttat aatagaagac aatcatctgc tatgaataaa tatattgaaa atgatattga
     7861 aaaacaaaaa tatttccata agcgatttta tgaattgtta aataagaatg atctatataa
     7921 tttatataga aagcgttatt taagtaatcg tgtaaaaatg tactctacgt taatttctaa
     7981 tgctactcgt gcatcaaata aaaaagttgg aatacaagaa attaagaaaa gtagagaatt
     8041 atttttaaaa gatgattatg taaattctac ttcactgaaa tctctctata attctaagtc
     8101 cattcaattt gctatctatt tattacggca taataaagtt gttttattat attctattta
     8161 cagacttaag gaaaaaaaga gattaaatca atttaactaa attaaatagg agaagaaaaa
     8221 gagtgaatcc agatattact gttatagttc caatttataa tgttgaaaaa tatattagaa
     8281 agtgcttaga cagtctgaaa agacagacat acaagaactt tgaagtttgg gcaatagatg
     8341 atggctctcc tgataattct aaaaagattg ttcaagaata tgctgataaa gatccaagat
     8401 ttaaatctat tttaaaagaa aatggtggct atgggtcagt tttagaatat ggaattaaga
     8461 atacaaaaac aaaatatttt ttagtttgtg atcctgatga ttggctaaca gatgatgcat
     8521 tggaaaaatt acataatttt gcaaaaaata gtaatttaga tgtaactgtt ggtgataaat
     8581 ataatattta ttcagaagat aataaaaaag tatacattcc tagttttaaa aaagagttaa
     8641 atgtaaaacc acgtgttgca tatgatacgg ctgaaaaaaa ggatagattt atttttagtg
     8701 aagtatcacc acatgcaaaa ttatttaaaa catcaattgc aaaaaatata gattttcctc
     8761 ataagattag ctatacggac actattttgt atgtgttgtc gattgctaat gcaaagagag
     8821 taggatatct ggatgaagct cttgcatact acttgataga tcgtcctggt aatactatga
     8881 cagcaaagac tgaagctaaa attagggata ccattaaaat atggcattcc atttataatc
     8941 agttgataaa tggatttgag ctaaatcaaa ttgaaacata tatatatttc ttatattatg
     9001 aaatgaaaat aatacttatt acagaatctc agctaccttc tatgagtaag tatcatactg
     9061 agattttaaa aattatgaga ataatgcaaa gatataataa gatattagct aaatatgtga
     9121 ataataaggt tgttccatat aatacaaatt ctatgactgg acgcttaata ttcaaaggat
     9181 ttatgaataa agcaacatat aaatgggtag agagattata tgttaaatta gagaggaaac
     9241 gtgaagctta aaatgaccaa ttatttaatt gtaggatcag gacttttcgg agcagtattt
     9301 gctcatgaag tagcaaaacg aggcaataaa gttactgtaa ttgaaaaaag aaatcattta
     9361 gccggcaata tttatactaa agaagttgat ggaattcaag ttcatcaata tggtgcacat
     9421 atttttcata catcagacaa aaaagtatgg gactatgtac aacaatttgc tgaatttaat
     9481 cgttacacta atagtcctgt agcgaattac tatggtaaaa tgtacaattt gccatttaat
     9541 atgaatacat ttagtgaaat gtggggagta agaactccac aagaagctat ggacaagatt
     9601 aatgaacaac gtcaagaaat ggcaggaaaa gatccacaaa atcttgaaga acaagcaatt
     9661 tctttaattg gacgtgatat ttacgaaaaa ctgattaagg gatatacaga aaagcaatgg
     9721 ggtagaaaag ctacagaatt gccagcattt attattaaaa gacttccagt tcgtttaact
     9781 tatgataaca attactttaa tgatgattat caaggaattc ctaagggtgg ttatactcaa
     9841 atagtagaaa aaatgcttga taatgagaac attgaagtta agttaaatac tgatttcttt
     9901 gataaaaagg atgagtattt aaagaatttt gataaaattg tctacacagg catgattgat
     9961 aagttctttg attataagtt aggcgaactt gaatatcgtt ctcttcgttt tgagactgaa
    10021 gaaaaagatg tagataatta tcaaggtaat gcagtaatta attatacgga tgcagaaact
    10081 ccatatacac gtgtaattga gcacaaacat ttcgaatttg gtaaaggcga taagggtaag
    10141 actatcgtta ctcgtgaata tcctgctaat tggaaacgtg gagatgagcc atactatcca
    10201 gttaataatg aaagaaacaa taatttatat aaacaataca agggtctggc tgaaaaacaa
    10261 aataaagtaa tttttggcgg tagattagga caatacaaat actataatat ggatcaggta
    10321 attgctgagg cattacgtat gagtaacagt gtagaataat gaatatggat ttaaaaaaga
    10381 aagaattaac aaattttttt tgtatagttt attttatttg gggcttattt caacaaattc
    10441 aaaatactgt taacataaaa tttaaatttg aagaaagtat aggacagatt ctaaatgttt
    10501 ttcttttagt aagtatgttt tttttactat tattagtaat gaaaaatcaa aactttgagg
    10561 ttaggatttg gaatattata tctctgattt tgttttttgg gctaattatt tatttaagta
    10621 aaaatcaaaa tttcactttt attgctacgt atgcattaat tttgatggca ggaaattttt
    10681 attttgaaga tattttaaaa actttcctta tatttaccgc cattatactg atttcaacta
    10741 tatttttgtt taaactggga cgtattccaa atgctatagt cgtaggtcag taccttaggg
    10801 taaggtcaag cctaggattt ggatattata catattcggc acagttgtta ttttatttca
    10861 cattagcata cttagttttt agaaaacaaa aaattacgta tgtagagcta ataattttag
    10921 aagccgcaaa ctattttatt tactatagta ctaatacaag aaacccatat attttatcga
    10981 cactttttat tttgtttgta ttagtagata agatttttaa gtttaaatta gatattttaa
    11041 gatttaaatt ggtaaaattt attatattat ttgcttttcc aatatgcttt attgtattaa
    11101 atgttttaat gttctggatt cctaaatctt tattttatac tttaaatgag gcgttatcgg
    11161 gtcgattggc attaaatatc tcaggactac aaatgtgggg agtaaaacta cttggacaaa
    11221 aaattgattt tgaagcgatt aatgtaaatg gaatggctac tcagtattac aattttgttg
    11281 atagttcata ttttcaaaca ttactggtaa gtggatgtct attttttatc ataattatga
    11341 tattgctaat ttatatatgt aataaatcta taaaagagca tgaacaatat ttaggaatag
    11401 ctttattttt aattgccatt cactctatgt ttgatcccca attattatta ccatggtact
    11461 ccccattttg tttgttatta ggacagtttt ttgctgtaca cgattcttca atatttgaaa
    11521 aaacaataca agaataggtt gatagaatga aagtaataaa aaactattta tataatgttg
    11581 ggtatcaagt attggcaatt atcgttccac ttattacatc tgcctatgtc agtagagttt
    11641 tgcggccaga gggtgtagga gcgaattcat ttactaattc tataatccaa tattttattc
    11701 tatttgctaa tatgggtatt gggtattatg gaaatcgaca aattgcgtat gttcgtgaaa
    11761 agaaaagtca aatgactaag accttttggg aaattcaaat tgtaaaaaca atcatgactc
    11821 tttacgcatt cgttgcattt gaaattttta tgatttttta cagtaagcaa cccgaatata
    11881 tgtgggctca atcactaaac ttagtagcag tagcttttga tatatcatgg ttttatgaag
    11941 gcattgaaga ttttaaggta actgttttaa agaattcatt ggtaaaaatt ttatcaatga
    12001 ttgcaatttt tatgtttatc aaaggaccaa atgatgtcac tttgtacata atagttctag
    12061 ctttgtcaac gttaattgga aatctaactt tatggcctaa cattgtacgt gatttagata
    12121 gaataaatat taaactctta aatccgtggc aacacttttt ccctatggct gaattgttta
    12181 ttcctcaaat tgcaactcaa gtatatgtcc aacttaataa aactatgttg ggagtcatga
    12241 taagtgaaac gtcttcagga tactatcagt attctgataa tttagtaaag cttattcttg
    12301 cattagtaac tgctacggga acagttatgt taccccatgt tgctaatgcg gtttcacatg
    12361 gcaatatgaa taaagttaac aaaatgcttt ataagtcatt tgattttgta tcggctgtct
    12421 cttatcctat gatgtttgga ttagcagcta tttcattaac tttggcaacg aaatattacg
    12481 gtcctggtta tggtcctgtg ggtcctgcta tgatgataga tcaattgtta ttttaataat
    12541 tgcatggagt aatgtattag gagtacagta cttgctgcct atgcataagc aaagagcatt
    12601 tactatttct gtaactctag gagcgtttat taatttggcg ttaaatattc ctcttattaa
    12661 aatatgggga ttaaatggtg ctatgtggtc tacagtttta tccgaacttg ctgtaactct
    12721 atatcaacta tgggcagtta aagatatgtt gagtattaga agcttgtttt caagtacgtg
    12781 gaagtacttt ttatctggat tgtgtatgtt tattgtagta ttttggatga atacgcattt
    12841 aaaagataca tggcttatgt taggtgtaga agttttaata ggaatagttg tgtatgctgt
    12901 atttatagta gttttgaaag ctaaaatcat tgatcaacta aaagatctag taggaaataa
    12961 gttgaataga taagtgagat cgtaaattga gtaatagaaa acatagaaat tatggtttag
    13021 atttagtaaa aatcctagca tgtattttag tattgtgtct tcattcttta gttccaacaa
    13081 gtccagtagt taaaaatagt ttacttaatt taagtgttta ttatgctggg gcaattgcaa
    13141 ttcctatatt ttttatggca agcagttatt ttgttttaaa taaaagaatg atgtcatatt
    13201 cttatgttat gagaagagtg ggagaaattc tttttataat aattggctgg gtattaatat
    13261 atagtatagt tcatttatgt ataaaacata attttatttt tcttgaagaa ctgaagggga
    13321 ctgcttttgt aggaattcca aatcagcatt tttatcactt ttggttcttt tgggcactta
    13381 ttattatgct gttgttatcc ccattattat ggtatctttt gcaaaaaagt tttgtaggat
    13441 atttaatttt gacaagtata gttactttga tttgtatagg tattgatatt tcgatgcatt
    13501 ttggcaacag ttctaatatt cggaacatac cacagatttt tagactatat ttatatattg
    13561 aatactatct tttaggtggc ttaattggaa atactaattt tgagaaaata aaaaattttt
    13621 gcaagcaaca ttttgtaatg acatgcattg tagctagttt tttatatgtt ggagtgatcg
    13681 catattcaat ttggaataga aatataattc attggtttta tgctgaggca aattatggaa
    13741 atgctctgat tatatttact tcagtattga tacttataat tttttctatt tcttctccac
    13801 ctaataaaag tacaattgaa tttattattc ctgcaacaat gggaatatat atgcttcatc
    13861 cattttttat tggtaaatta atgaagattc atattttata taattatcct atttttatga
    13921 ttcccgtttt gttcattcta tgtttgataa ttgtagaaat tgctctacgt attccaatta
    13981 ttaatcgttt ctttaaatta taaaaaataa aagcaaaaaa acactgtgta gttaatcact
    14041 acacagtgtt ttttcgagga gttggaaagc ttataaattt agttattttg taagcgtcaa
    14101 ataaccgagt gtctcgatcc aactttcact ttcagctatg attaatttat caattcaatg
    14161 ggggggaatc atatgctcga aaagcaacag ccaattgtgg cactcaatca tccaatcata
    14221 ccgaagaaga ctcggccact acgcaataat ctcttgctca gtttgaaaaa gaacgatctg
    14281 gaactgaact tctatagcag tttagatcct gaaataatga ataaactctt agagaaagtc
    14341 ttatcatgat caatctttat acactgggtc aggtttatat cgtttgtggc aagaccgatc
    14401 tgcgcaaagg aattgatgga ctagcaacac tagtcaaaga acagtttgaa ctggatccgt
    14461 tcagtggaaa agtcttcctc ttttgtggtg gacgcaaaga tcgtttcaag gccctttatt
    14521 ggacggtcaa ggattttggc tgctctataa aagatttgaa aacgggaaga tgaactggcc
    14581 gcgaaaccaa aatgaagttc aagctttatc ttctaaacaa gtcgactggc tgatgaaggg
    14641 cttcgcaatt agtccaaaaa taaagaacac gaaagcacgc gaattctact aacacttgat
    14701 atcgcgcgct tttttggcat aattttaact aacaaaattt aggaggaagt ttgaattatg
    14761 tcacaagaaa atttggaaaa gattatttcc caacaggcaa ctaccattca aaacctaact
    14821 gatgagatca agcttctccg tgaacaagta gcttacttaa cgcaaaagca ttacggcaag
    14881 tcttcagaac aaatgtcctt gaatggccaa acaagtttat ttgatgagtc tgaagctcaa
    14941 gatgacggag agcgtccccg acgccgccat tcagactatt acttatagaa gacaagctca
    15001 cacgagaaaa agagccgacc tgttagcagg ctttcctgct gagtaagttc atcatgaatt
    15061 ggacgataag cactgcccta attgtcatca tgagttgaaa gaaattggcg cttatccgat
    15121 aagacaggaa ttgcttttca ttcccgctca gcttaagcgc ttgaatcaca tccaacatgc
    15181 tttcaaatgc caatactgca gtcagagaag tcttagcgac aagatcatta aagccgcagt
    15241 acctaaggca ccattgaatc acggcctagg atcaccttcg cttattgccc atactttata
    15301 tcaaaagtat gagttgaaga tcccagatta tcggcaagaa agcgactgga aaaagatggg
    15361 gctagaagtt tctcgacaaa tgttaaatca ctggggactg aagagtagcg aatattactt
    15421 taagccgtta tatgacgtgc ttaaacaaaa gctgttaaac cgaccaatct tgcatgccga
    15481 tgaaacctat tacaccgtgc tggaaagtga gacaattaaa acctattatt gggtctttct
    15541 ttctggcaag catgatcgct atgggattac actgtatcat catgatccgc accgcagcgg
    15601 ccaagtagca cttgattttt taggcaacta ttctggctat ctgcactgcg atatgtggca
    15661 ggcttatgaa cagctgcctg aggcaacctt ggttggctgc tgggctcatg ttaggagaaa
    15721 gtttcatgaa gctatgccac aaaatgcttc tggcaagtgc attgccaggc aagggcttaa
    15781 ctattgcaat cggatgttct gcttggaaaa agcttgggaa tctttagatt gtcaaacacg
    15841 ttatcaagct agaaaagaag aactcaggcc attaatgcag gagttttttg aatggtgcag
    15901 gaaaaataaa gcaactgttt ttgcctggtt ctaaactagg caaagccatt aattatgcgc
    15961 tcaagcatca agaaactttt gagcatgtct tgcttaatgg ccgcttagaa ttatccaaca
    16021 acaaggctga acgagctgtt aaatcactcg tgataggtcg caaaaattgg ctattttcac
    16081 aaagctttgc aggggctact gctagtggca tcattttaag tttaattgaa actgctaaaa
    16141 gaaatgatct tgatcctgaa aagtacttaa attacttgct tcaaaaatta ccgaatgaag
    16201 aaattttaga ttcggatgct cttgaagctt atttgccatg gcaagcaaaa attcaaaaaa
    16261 tgtgtaaata gaagacatcg caagaagacc gccctagaac aactaggacg gtctttcaat
    16321 atacttggtt atttgacgct tactatactt tttatgaaca ctatatctgt acttgataaa
    16381 tttatctttt atttatatca ttatatatgc gttatgatga aattaggcat aacggagaag
    16441 gattgttgtc aagatcttgg tcgagaattg attaataata aattcaatgc caagtttgat
    16501 gactgaagaa tgtgtttctt gatctaaggt aatccagaag acttccacaa ttaatagaag
    16561 aacttgtaat cttggagaaa gactcataac aattcctttc gtctttataa taacatgaag
    16621 atgcatgata ttactgagta gttgtaattc atctcagtgt ttatctgtca tggattataa
    16681 gattttttac acagtaccca ctggttagga acgctactct ccgttgccag tgggtatcgt
    16741 catttattgg ggtaattatg aatattaatg aatggtttga agacccaaaa gtatttgaaa
    16801 agagtaaaag agaatatgca cattttgatc ttcgaactga tttagctaaa tgcaagaaat
    16861 atattactaa ttctaaaaat attgagcgac atggttttta tccgtttata aaatatgatc
    16921 ttgaatatca taaatataat agggcggaag gaagaaaaac aaagaagcgt accatttgtt
    16981 atgcatctca tattgatagt tgtatttttc aatattatag ttttttaatt aataaaaaat
    17041 ataatgcacg tctaaaacaa gatggcattt acgaagtgcc aatagcatat cgaacagatc
    17101 tacatacaga tactattgct gaatttagaa aaatgcatca gttcatgatt cagcatcctt
    17161 cttcttatgt tatgattggc gattttacaa gcttttttga caaaattgac catcaatatt
    17221 taaaagagcg cttatgtgat ttattacaag tcgataagct taattccgat tattatgcga
    17281 tatttaaacg aattaccaaa tatgattatt gggatttaac agatctctat cgattaaata
    17341 atcttaatcc aaagaagaga aaagataaga ttaagataaa ttctaaagta agaattctct
    17401 ctcaaagtga ttataagaaa tatcgatcac acattaggca acatcaagac aataaaggaa
    17461 ttccgcaagg ctcatcaatt agtgcatgtc tagcaaatgt ttatatgtta gaaattgatc
    17521 ggctgattaa tgaatttgta gttgcacgtg gcggtattta tagaaaatac agtgacgatt
    17581 ttataattat cttacctatg gatactagtt caactgatga tattgaaaaa ataattctaa
    17641 aatttggagc atttaaagat aaaggtattt tggaattaca accagaaaag acgcaagttt
    17701 ataaattaca agaccattca gtcgtgaata tcggtcatct ttttactccg agcttgaatg
    17761 aaaagaacaa aacaattaat tttattggct ttacttttga cggtaatgca ataaaaatac
    17821 gcgaaaaaac aacaagtaaa tattattatc gaatgcatca taaagctaaa ggtgtcgctc
    17881 atcaatatta tcgtaataag tattacaagg gtgcagataa gttatatcaa ctgtattctc
    17941 caaatggtca gtatggaaaa ggtaattatt ttacttattt aagtagagtt cagaatgctt
    18001 tccccaacca atctattatg atttcagagg ataggattat gacgaatatt aggctgactt
    18061 tgaagaaaaa taggtgggga taggagtaga gatgcattct caaaggctag aattgatttt
    18121 gagaatttaa ggggatcatt tgtaaaaaga aaagaaaata tgatatcgct aattatgggg
    18181 agaaaaaact ttccattggg atggcaaaaa tttggaatta gtaattaagg tttatttggc
    18241 aggttaatat ttgtagataa aaagatagtc cttttgttca gtggactatc tttttaatat
    18301 ggataattat gaagaaatat taatgtgctt agttaggatt ttatgacttc cttagctgtg
    18361 ggagggtaga ctaaaaaaca aaataataag aataaatgtg cctattaact tgtttttaaa
    18421 agaggtaaaa tgattctgaa tagtacttgg agtgaaaaga atgctttata aacaaattga
    18481 acagaataaa cgaaatactt ggattatttt aggtctatac accttgttga tactaataat
    18541 aagtattttt cttgggatgc tttttacagt ttatattgga gggttattct ttgttatagg
    18601 tttgatttac attgcacacg tctactttga tgcaactcgc catcttatga aagtaacaaa
    18661 tgctgttgaa atcactaaag aaacagagcc ccaaatttat gaattagttg aagaactctg
    18721 tttagccggt gggttgccag ttccaaaatt atatattact cctgatcagg cgccaaatgc
    18781 gtttgctacc ggacgcgatc cacaacatgc aagtttagct ttaacgcaag gactattgaa
    18841 tatgatgaat aaaaaggaag ttcaaggtgt cattggccat gaactttctc atattcgaaa
    18901 ctatgatact cgtattacag ttttagccag tgcgctaact agtttaatta caatgactgg
    18961 tataggaatc gttgtatttg gatggggtgt attaactagt gagagtaaag gtttgttagg
    19021 tcttctcatc aaattttttg ccttattttt gattattgta ggtggaatta tttctattat
    19081 tggaattcct atagcaaagt tgctattttt actagtatca cgtcagagag aatatttagc
    19141 ggatattggt tcagttgatt tgacacgtga accaagcggc ttaatttctg ctctgtctaa
    19201 acttgaaaag ctagaagaag gagagagtat tccacaaatt ggatcacaag atttagccct
    19261 acaacatttg tattttaatt ttccgagtgc tcataattgg attaaccgcc ttttctccga
    19321 tcatccacct ttggataaaa gaattgaacg cctagaaaat agtaatcgga taaaataaga
    19381 taagcacgac caaatatcat gagatggtat ttggtctttt tgttgggtta agctgtaggt
    19441 taagcactct attttttgtt gatagaaact aatggaaaat gatattattt gaattaggga
    19501 atggcattat atcagagatc ttttagtgta ttctccacgt aagtggagct gcttctgatg
    19561 ccccccaagt atgaagattt cgcagtgcct tggtgttctc catgtttgtg gaggtaatcc
    19621 catgaaaagt ggtgttggca aaattactaa ctcgtattct ccagtaaata aaaaatgcca
    19681 catcattcaa aacatactat atctatacaa tcctacgtta atcagttgaa tgacttgata
    19741 gctcatatta gttgatttat ataaaaaata tcaagagaga aaaaatatga caccatcaat
    19801 tgactaaagg ccaataggat ttgctacaat aaatgaaggg acaagtgaac gtagtttatt
    19861 agaaagaaga acaatggcac tatgctaaaa aagtgattca cgagtctact atgaaagtaa
    19921 gagatagtta ggtgaacgcg catagaggtc agataggtgt gggtgcgagc cccatcttgc
    19981 ttgtcttaaa gaaaacgata ctcaaacgag tgtcgttttt attttttgtt tttttctcaa
    20041 ggataggact taaatattta ataaagataa ttcaaatcat catccctaaa tacattaact
    20101 ctacttgtta tgaaataaag cattgataag gtatttctat ttgttatacg gctgtaaaat
    20161 catcacgtaa agcaggttta aagcctactc tcataacagg ctaatccgta atttgaaaac
    20221 taaattcgtt atataatctg tataattttt taggagtatt aggtttagta cttctggaat
    20281 taggaacaag tgcttgctct agtcaaacaa acaatagtag cagcaaacaa atactagtaa
    20341 gtcaaagaag tctgtcgaaa agacagatga aagcagtagt tagagtacaa aacgctctaa
    20401 aaaagattta agtacagcgg ctgacaatca agctaataat agtaacagta acgaaggtaa
    20461 agcttatggc ggaaatttcc aagatagtaa gggatatatc gctatcaata atgtaaccaa
    20521 cgtcactgtt aagagttcta atgacgatgg ctactatgct ctagtgcaag gaactttcac
    20581 taataatgct aaagaaagcg ttgatccaac atcttacttt agtaaccact taaaagtaat
    20641 ggagaaaggt ggcaaagcta ctcatgatct tgttttggtc actacagaca ttgaaaatga
    20701 attaacacct tggggaaacc agattaagga aggtcgtaag aaggttggcc taatatgacc
    20761 ggtaattttg ttatagtata taaattagat cctgcaaatg gagctaaaac taatgcaacc
    20821 cattatgtat tcgatcctta cgattctaaa tttggtaaat cattaactgt aaaagtttat
    20881 gagtctaaga ccattaagaa atctagcgat agtgcaaata gcaattcaca ttctgacgaa
    20941 agtacagaca taaattcaag tgccgataca agcagtgatg ctgatacaga tgactaatta
    21001 aatattaaaa aactgagaac tatgagggta ttcataattc tcagtttttt tattaagtag
    21061 cattattgtc caattagttg ctggaaatcg ctaactagtt tttgaaaagt tgcatttaaa
    21121 ttctgcataa attcgttttg attatttttc atttgatcta ataatgaatc ggcctgattt
    21181 ggattttgtt tgatttggtc gatagtagag cccaattgat caatttgatt ttgtaaggct
    21241 tgattattag cagcattatt tttcaattgt tcattttccg ttttgatttg gtttaattgg
    21301 ttttgtaatt cttctttatt ttgatcctgc ttataggtat tgatagcact ttgcaactct
    21361 ttattttgtt gcattaattg cttgttttgt tcagacagat tatctaattt actgttagta
    21421 ttattgaggg cattactttg agcttgctca ttttgaaccg tatcattatg agcctgacaa
    21481 gctgaaatac caaagatgat ggcaattaat aaaacaagca ctccaagaac aatatatact
    21541 atctttttct tgcctttctt tttaggacta gcagctttat taggagaaga agtatattgt
    21601 gctgttttta ctggagctgg ttgaggagta ggggaagaat caaccatatt atttttatct
    21661 gttacccagg cttgaatttt tttggtccca tattcgttat tagtgccaat cgctgtaata
    21721 attacaggat atactcctgc ttcagaccgg ttaacggcct ttttatttat actaagatta
    21781 tcatttgaaa taagatggcc attttctgta actgtaagtt ccaattgaga gattatttct
    21841 tgattggtca aattctgatt aagaggccag gtaattgagt ctactctggt attgatttgt
    21901 aatgtcatat ctaaattcct ttgaaaaact ttagtctatt taattcgatt atactaataa
    21961 aatttactta gagaaattaa ttaacagcag taaaataaaa cttaaacaat tataaactat
    22021 ataaataata taattaaaat tatgtaaaat ggagaagaaa tgaaaagatc agaaaatgtg
    22081 actttaacta atatgtgtat gataaaagat aaagataaaa ttttagttct aaatagaact
    22141 gatccagttt ggcctggttt aacttttcca ggcggccacg tcgaatctca tgaagctt
//
