Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000773.1:
Cluster 1Saccharide115943

BGC0000773, lipopolysaccharide biosynthetic gene cluster from Escherichia coli. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: lipopolysaccharide
PubChem ID: 11970143
SMILES string: Copy to clipboard
Molecular formula: C205H366N3O117P5
Average molecular mass: 4899.956 Da

Class-specific details

Biosynthetic class(es):
Saccharide

Gene cluster description

lipopolysaccharide (BGC0000773). Gene Cluster 1. Biosynthetic class = Saccharide. GenBank AF125322. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

Literature references

1. Marolda CL, Valvano MA. (1993) Identification, expression, and DNA sequence of the GDP-mannose biosynthesis genes encoded by the O7 rfb gene cluster of strain VW187 (Escherichia coli O7:K1). J Bacteriol 175(1):148-58.
2. Marolda CL, Valvano MA. (1995) Genetic analysis of the dTDP-rhamnose biosynthesis region of the Escherichia coli VW187 (O7:K1) rfb gene cluster: identification of functional homologs of rfbB and rfbA in the rff cluster and correct location of the rffE gene. J Bacteriol 177(19):5539-46.
3. Marolda CL, Valvano MA. (1996) The GalF protein of Escherichia coli is not a UDP-glucose pyrophosphorylase but interacts with the GalU protein possibly to regulate cellular levels of UDP-glucose. Mol Microbiol 22(5):827-40.
4. Reeves PR et al. (1996) Bacterial polysaccharide synthesis and gene nomenclature. Trends Microbiol 4(12):495-503.
5. Marolda CL, Valvano MA. (1998) Promoter region of the Escherichia coli O7-specific lipopolysaccharide gene cluster: structural and functional characterization of an upstream untranslated mRNA sequence. J Bacteriol 180(12):3070-9.
6. Marolda CL et al. (1999) Genetic organization of the O7-specific lipopolysaccharide biosynthesis cluster of Escherichia coli VW187 (O7:K1). Microbiology 145 ( Pt 9):2485-95. doi: 10.1099/00221287-145-9-2485.