BGC0000774: lipopolysaccharide biosynthetic gene cluster from Xanthomonas campestris pv. campestris
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Location: 1 - 37,753 nt. (total: 37,753 nt).
This entry is originally from NCBI GenBank AF204145.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000774
Short description lipopolysaccharide biosynthetic gene cluster from Xanthomonas campestris pv. campestris
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (lipopolysaccharide)
Loci
AF204145.1
via Knock-out studies
Compounds
  • lipopolysaccharide
Species Xanthomonas campestris pv. campestris [taxonomy]
References
Chemical products information
lipopolysaccharide Evidence:
(no structure information available)
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AAK53494.1
  • wxcX
 134 - 772 (+) conserved protein involved in carbohydrate biosynthesis
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    • AAK53493.1
    • lpsJ
    		 1054 - 1692 (-) beta-subunit of putative 3-oxoacid CoA-transferase
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      • AAK53462.1
      • lpsI
      		 1692 - 2420 (-) alpha subunit of putative 3-oxoacid CoA-transferase
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        • AAA27610.1
        • xanA
        		 2555 - 3901 (+) phosphoglucomutase / phosphomannomutase
        • Precursor biosynthesis
        • Activity assay
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        • AAK53463.1
        • xanB
        		 3947 - 5350 (+) phosphomannose isomerase / GDP-mannose pyrophosphorylase
        • Precursor biosynthesis
        • Activity assay
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        • AAK53464.1
        • rmlD
        		 5472 - 6380 (-) dTDP-4-dehydrorhamnose reductase
        • Precursor biosynthesis
        • Knock-out
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        • AAK53465.1
        • rmlC
        		 6377 - 6934 (-) dTDP-4-dehydrorhamnose 3,5-epimerase
        • Precursor biosynthesis
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        • AAA16191.1
        • rmlA
        		 6931 - 7818 (-) glucose-1-phosphate thymidylyltransferase
        • Precursor biosynthesis
        • Knock-out
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        • AAK53466.1
        • rmlB
        		 7882 - 8937 (-) dTDP-glucose 4,6-dehydratase
        • Precursor biosynthesis
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        • AAK53467.1
        • etfS
        		 9166 - 9912 (+) putative electron-transferring flavoprotein beta subunit
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          • AAK53468.1
          • etfL
          		 9912 - 10856 (+) putative electron-transferring flavoprotein alpha subunit
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            • AAK53469.1
            • wxcH
            		 10916 - 11263 (+) WxcH
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              • AAK53470.1
              • wxcK
              		 11312 - 12415 (+) nucleotide sugar aminotransferase
              • Precursor biosynthesis
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              • AAK53471.1
              • wxcL
              		 12400 - 13371 (+) glycosyltransferase
              • Scaffold biosynthesis
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              • AAK53472.1
              • wxcM
              		 13368 - 14297 (+) bifunctional nucleotide hexosamine acetyltransferase / isomerase
              • Precursor biosynthesis
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              • AAK53473.1
              • wxcN
              		 14284 - 14724 (+) putative integral membrane protein WxcN
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                • AAK53474.1
                • wxcO
                		 14794 - 17046 (+) integral membrane protein
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                  • AAK53475.1
                  • rmd
                  		 17188 - 18126 (-) GDP-4-dehydro-D-rhamnose reductase
                  • Precursor biosynthesis
                  • Knock-out
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                  • AAK53476.1
                  • gmd
                  		 18110 - 19144 (-) GDP-mannose 4,6-dehydratase
                  • Precursor biosynthesis
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                  • AAK53477.1
                  • wxcE
                  		 19222 - 19857 (-) Unknown
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                    • AAK53478.1
                    • wxcD
                    		 19857 - 21602 (-) putative glycosyltransferase
                    • Scaffold biosynthesis
                    • Knock-out
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                    • AAK53479.1
                    • wxcC
                    		 21623 - 22684 (-) glycosyltransferase
                    • Scaffold biosynthesis
                    • Knock-out
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                    • AAK53480.1
                    • wxcB
                    		 22734 - 25022 (-) putative protein kinase
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                      • AAK53481.1
                      • wzt
                      		 25062 - 26348 (-) ATP-binding component of an ABC-type polysaccharide exporter
                      • Transport
                      • Knock-out
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                      • AAK53482.1
                      • wzm
                      		 26345 - 27130 (-) permease protein of an ABC-type polysaccaharide exporter
                      • Transport
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                      • AAK53483.1
                      • wxcA
                      		 27214 - 28599 (-) glycosyltransferase
                      • Scaffold biosynthesis
                      • Knock-out
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                      • AAK53484.1
                      • uptH
                      		 28596 - 29795 (-) cystathionine gamma-synthase
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                        • AAK53485.1
                        • uptG
                        		 29889 - 31259 (-) cystathionine beta-lyase
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                          • AAK53486.1
                          • uptF
                          		 31491 - 31985 (-) UptF
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                            • AAK53487.1
                            • uptE
                            		 32051 - 32941 (-) putative outer membrane protein UptE precursor
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                              • AAK53488.1
                              • uptD
                              		 32938 - 33321 (-) putative outer membrane protein UptD precursor
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                                • AAK53489.1
                                • uptC
                                		 33420 - 34553 (+) type II secretion system protein-like protein
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                                  • AAK53490.1
                                  • uptB
                                  		 35073 - 35735 (-) putative maleylacetoacetate isomerase
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                                    • AAK53491.1
                                    • uptA
                                    		 35779 - 36768 (-) putative dioxygenase
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                                      • AAK53492.1
                                      • rhlE
                                      		 37148 - >37753 (+) putative ATP-dependent RNA helicase
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                                        Biosynthesis information
                                        Annotation changelog

                                        Entry version: 3

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2022-09-15
                                        Corrected gene identifiers
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 2

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2019-10-16
                                        Migrated from v1.4
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        2019-10-16
                                        Updated compound(s) information (MIBiG Annotathon)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                        Entry version: 1

                                        Date
                                        Changes
                                        Submitters
                                        Reviewers
                                        2015-06-12
                                        Submitted
                                        • (ID: RXWHZKRGAGJ7NL3JTIYKSUAE)
                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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