LOCUS       BGC0000783             13187 bp    DNA     linear   BCT 25-JUL-2016
DEFINITION  Xanthomonas oryzae pv. oryzae putative cystathionine gamma-lyase
            (metB) gene, partial cds; putative sugar nucleotide
            epimerase/dehydratase (wxoA), putative glycosyl transferase (wxoB),
            putative glycosyl transferase (wxoC), putative o-antigen acetylase
            (wxoD), putative ISXo8 transposase, putative IS1113 transposase
            (tnpX1), truncated putative transposase, putative ATP binding
            protein (wzt), and putative ABC transporter system integral membrane
            protein (wzm) genes, complete cds; and putative electron
            transferring flavoprotein alpha subunit (etfA) gene, partial cds.
ACCESSION   BGC0000783
VERSION     BGC0000783
KEYWORDS    .
SOURCE      Xanthomonas oryzae pv. oryzae
  ORGANISM  Xanthomonas oryzae pv. oryzae
            Bacteria; Proteobacteria; Gammaproteobacteria; Xanthomonadales;
            Xanthomonadaceae; Xanthomonas.
COMMENT     On Jul 7, 2003 this sequence version replaced AF337647.2.
            ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 20:34:19
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     gene            <1..642
                     /gene="metB"
     CDS             <1..642
                     /codon_start=1
                     /gene="metB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1168:O-succinylhomoserine sulfhydrylase (Score: 270.1;
                     E-value: 4.2e-82)"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to Stenotrophomonas maltophilia
                     cystathionine gamma-lyase-like protein"
                     /product="putative cystathionine gamma-lyase"
                     /protein_id="AAK21284.1"
                     /transl_table=11
                     /translation="DNTFASPMLQRPLSLGADLVVHSATKYLNGHSDMVGGIAVVGDNA
                     ELAEQMAFLQNSIGGVQGPFDSFLALRGLKTLPLRMRAHCENALALAQWLETHPAIEKV
                     IYPGLASHPQHVLAKRQMSGFGGIVSIVLKGGFDAAKRFCEKTELFTLAESLGGVESLV
                     NHPAVMTHASIPVARREQLGISDALVRLSVGIEDLGDLRGDLERALVNQN"
     source          1..13187
                     /country="India: Eastern India"
                     /db_xref="taxon:64187"
                     /mol_type="genomic DNA"
                     /note="type strain; pathovar: oryzae"
                     /organism="Xanthomonas oryzae pv. oryzae"
                     /strain="BXO1"
     subregion       1..13187
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000783"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..13187
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1522..2607
                     /gene="wxoA"
     CDS             1522..2607
                     /NRPS_PKS="Domain: NAD_binding_4 (77-270). E-value:
                     5.2e-13. Score: 40.5. Matches aSDomain:
                     nrpspksdomains_wxoA_NAD_binding_4.1"
                     /codon_start=1
                     /gene="wxoA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     213.2; E-value: 9.4e-65)"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to Mycobacterium avium GepiA and putative
                     epimerase from Streptomyces coelicolor A3 (2)"
                     /product="putative sugar nucleotide epimerase/dehydratase"
                     /protein_id="AAK21285.1"
                     /transl_table=11
                     /translation="MEKAVIAVIVTGGAGFIGCALSGQLKAFGLPVVAIDNLHPQIHAE
                     SKRPEVLDEAAHLHIGDVTEENTWGQVLENWQPTIVVHLAAETGTGQSLTEATRHAHVN
                     VVGTTAMLDAFSARKLVPEHVLLASSRAVYGEGAWLDANGTTFYPPPRSHEVLARSQWN
                     PLSPSGRGAASPLSHRPDTVFPNPTSVYGATKLAQEHILAAWCGAMQVPLSVFRLQNVY
                     GPGQSPFNSYTGIITLFHRMARKAQTLEIYEDGEIGRDFVFIDDVVVALMAGLRQPPAG
                     FRTLDVGSGVVTTIAEAAKSIAAMHGAPDPQISGKFRDGDVRWAVADGAPLEQSLGVQA
                     RINFQEGANRVGEWLIARGYA"
     aSDomain        1753..2331
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_wxoA_NAD_binding_4.1"
                     /evalue="5.20E-13"
                     /label="wxoA_NAD_binding_4.1"
                     /locus_tag="wxoA"
                     /protein_end="270"
                     /protein_start="77"
                     /score="40.5"
                     /tool="antismash"
                     /translation="PTIVVHLAAETGTGQSLTEATRHAHVNVVGTTAMLDAFSARKLVP
                     EHVLLASSRAVYGEGAWLDANGTTFYPPPRSHEVLARSQWNPLSPSGRGAASPLSHRPD
                     TVFPNPTSVYGATKLAQEHILAAWCGAMQVPLSVFRLQNVYGPGQSPFNSYTGIITLFH
                     RMARKAQTLEIYEDGEIGRDFVFIDDVVVA"
     gene            3961..4560
                     /gene="wxoB"
     CDS             3961..4560
                     /codon_start=1
                     /gene="wxoB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 70.8;
                     E-value: 2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to putative transferase from Streptomyces
                     coelicolor A3 (2)"
                     /product="putative glycosyl transferase"
                     /protein_id="AAK21286.1"
                     /transl_table=11
                     /translation="MWRMLRHLVEKGLVAAQFLLVLGASYSHKNRDLAILAWKELRRRG
                     HNIALVMAGAVVAKGSSRQEEAVARWGADEEQLVIMPDVSSAVRNWLLRHASIVLYPTS
                     AEGFGLVPFEAASMGTPTAHVSFGPLRELIDSPELPQDWDPLRMADHCQQLLQDPQLAG
                     KNIKRVLASGGRLVWSATAADLTVAYRQTLASAPRN"
     gene            5365..6042
                     /gene="wxoC"
     CDS             5365..6042
                     /codon_start=1
                     /gene="wxoC"
                     /note="similar to ORF12 from Actinobacillus
                     actinomycetemcomitans"
                     /product="putative glycosyl transferase"
                     /protein_id="AAK21287.1"
                     /transl_table=11
                     /translation="MDIPAVLFLYLISTDVVRKVGIMDPCFGRGYCEETDWSLRSLAAG
                     YRIALAPGTYVFHHGRGSNLDAGLVSSNATTVPANEAIIDLRYPQFRNQVEAFVHSGVL
                     SRAHDDAISHIVRSAGKQFGYSIDVGWIGRDRTNEDEVNILLSPNGANDHIQAVFRGFR
                     LDMQVSRRNLGQEIPKFFGQDPTAGNLYDSGALATALKSEFAMVLTPEPVIILSEYRYY
                     GLI"
     gene            6097..7080
                     /gene="wxoD"
     CDS             6097..7080
                     /codon_start=1
                     /gene="wxoD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1088:acyltransferase 3 (Score: 76.7; E-value:
                     2.9e-23)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative o-antigen acetylase"
                     /protein_id="AAO20851.2"
                     /transl_table=11
                     /translation="MLVSHHFALAKLPEPLVLQFQTLGGYGVFIFFSISGFLVAQSWQR
                     DPSLVRFTYRRLLRIWPGMLCVLILCAFLLGPAVTTLSLKEYFLNELTWTYFKTMLFQV
                     QPFLQGVFPDSAVPYIPNGVLWTIPIEVHCYGYLAILGVIGVLRWRWVLLAATAALAVY
                     YYGYHDAENVFRAGGGRVHEIEFATFFFSGVLLHYFREIWSSWNRIIPSFLVVMTAFLL
                     LFQNDHQLIAVFLFTPFFFVVLGNLSFPIMRRFGRFGDMSYGIYIYAFPVQQTLFWLWG
                     ESISFNTSLALALTITGLLAWISWHLIEQPALRLKPRTPKRIMAGE"
     mobile_element  7096..8568
                     /mobile_element_type="insertion sequence:ISXo8"
     CDS             7167..8486
                     /codon_start=1
                     /product="putative ISXo8 transposase"
                     /protein_id="AAO20850.1"
                     /transl_table=11
                     /translation="MLNRSLEVRFEQYGEVVAAALSHADRKQPAHWYLKGLLLPGGRKS
                     VEPMAARVHPQNVGSAHQSMHHLVADADWSDQALLAAVAAQVLPPLSRKSAACHWIVDD
                     TGFSKKGVHSVGVARQYCGRLGKTDNCQVAVSLSIANEHGSLPVGYRLYLPEQWAQDTV
                     RRKKAGVPDQVVFQTKTALAMDQIDSALATGIAAGVVLADAAYGTETHWRDQLSERGLL
                     YMVGVRSNTKVWWGSHQPAPMPPASPKGGRPRTRPMRDSAHAPISVHEVAQRLPARTYR
                     QVSWRQGSDATLSSRFAAVRVRAAHNRQAHDEQWLLIEWPPGESEPRHYWFSTLPKQTL
                     VKTLVATAQGRWRIERDYQELKSELGLHHYEGRNWRGFHHHASLCIAAYGFLMRERLRS
                     KKNSVAFKMPAVSKSVRPRRSGPNATSPSQLDCHAGLRTG"
     mobile_element  8713..10019
                     /mobile_element_type="insertion sequence:IS1113"
     gene            8802..9986
                     /gene="tnpX1"
     CDS             8802..9986
                     /codon_start=1
                     /gene="tnpX1"
                     /gene_functions="other (smcogs) SMCOG1130:transposase
                     (Score: 473.2; E-value: 7.6e-144)"
                     /gene_kind="other"
                     /product="putative IS1113 transposase"
                     /protein_id="AAO20849.1"
                     /transl_table=11
                     /translation="MLDELTSGCKTPQDVEKLFSQMLQHMINRSLEAEMQAHVGHAPHG
                     RSGGNVRNGKSRKTVQSALGELQIETPRDRAGTFAPQLVKKRQVRLAGMEEKILALYAR
                     GMTTRDIESALVDVYGVEISHGLIAQVTDAVLEEARAWQSRPLEAIYPIVWLDGIVVKV
                     QHNKQVINKAAHVVLGVNLRGEKEVLGLWLAEHEGAQYWLSVLTELRHRGVRDIYIACM
                     DGLKGLPEAVQAVFPQTLTQLCIVHLVRASLRYVNAGDSKAVVAALKRIYQSATAEEAA
                     AELEALDTQWGDKYRAVVRLWRGNWDNIIPFFQFVPQIRKVIYTTNAIESLNMVMRKLT
                     RNRRIFPNDDSALKSLFLAVREASKNWRSIHHWKPALQSFQVMFGEERVPMNAL"
     CDS             10151..10498
                     /codon_start=1
                     /note="ORF8; truncated protein similar to putative
                     transposase encoded by GenBank Accession Number AF232058"
                     /product="truncated putative transposase"
                     /protein_id="AAO20848.1"
                     /transl_table=11
                     /translation="MALDQTTASGRAGDRTFETGLPLESLPSQRRPRRCTARARLRRWR
                     QPALAAALDRIFACLVAGGAGAFLNALKHHLAHKHGTGGLRGVFQGRLAAERALHLEIE
                     SNVFSGATTCS"
     gene            complement(10516..11829)
                     /gene="wzt"
     CDS             complement(10516..11829)
                     /codon_start=1
                     /gene="wzt"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 140.2; E-value:
                     1.5e-42)"
                     /gene_kind="transport"
                     /product="putative ATP binding protein"
                     /protein_id="AAO20847.1"
                     /transl_table=11
                     /translation="MCSDIAIEVKGLGKCFNVYDKPAHRLMQMLWRGRRRYYREFWALR
                     QVSFSIRRGETVGIIGRNGAGKSTLLQMICGTLTPTEGQITVNGRVAALLELGAGFNPE
                     FSGRENIYLAASLYGVDKKTISMRMESIATFADIGEFIEQPVKTYSSGMYVRLAFALIA
                     HVDAEILVIDEALSVGDAYFQQKCMRFLANFQRQGGTLLFVSHDMGALNALCESAVLLR
                     RRGEHYLCDVGSARDISAVYLRDLYSDRTTSAVTRASHPIQATYDSKNIEATRFHASPF
                     RSNADGFGAGGARIESVAFHNMLGDPLVEFNSSEDIRLTVVARLNKSLSYPAVGFMLKN
                     RKGQYILAESSDSYLREEAISIQEGSVLTVTFQLRLPRLIRGEYSLDVALAEGPGDDHV
                     QHHWLHDAIVLTAINSQLVHGISGAQPLSVSVRYSNST"
     gene            complement(11819..12637)
                     /gene="wzm"
     CDS             complement(11819..12637)
                     /codon_start=1
                     /gene="wzm"
                     /product="putative ABC transporter system integral membrane
                     protein"
                     /protein_id="AAO20846.1"
                     /transl_table=11
                     /translation="MEPYSGSPSSLLQSLIANRRLISALAVREISARYRGSLLGFTWAL
                     IQPIFMLAIYTFVFSEVFKARWLGGSGTKTEFALVLFSGLLVFNLFSEVFNRAPQLIIG
                     NANYVKKVVFPLEVLPVVSVLTAMFGLIVNLMVLLVFYLASYGVPPVTALLLPLAILPL
                     VLFMMGLAWLLSALGVFLRDIAQITAIITTAIMFLTPIFYPIDAIPPTFRPILNINPLA
                     PVIAQIRNVLIWGHGLKPLEYSLCLVISALVFITGFAFFQRTRKGFADVL"
     CDS             complement(12860..>13187)
                     /codon_start=2
                     /gene="etfA"
                     /product="putative electron transferring flavoprotein alpha
                     subunit"
                     /protein_id="AAO20845.2"
                     /transl_table=11
                     /translation="RGVGSAENFKHIYSLADKLGAAVGASRAAVDAGYVPNELQVGQTG
                     KIIAPELYMAIGISGAIQHLTGIKDAGTIVAINKDPESPIFEIADIGLVGDLFTLLPEL
                     EKVL"
     gene            complement(12860..>13187)
                     /gene="etfA"
ORIGIN
        1 gacaacacct ttgcctcgcc gatgctgcag cgcccgctca gcctgggcgc cgacctcgtc
       61 gtgcactcgg ccaccaagta cctcaacggc cactcggaca tggtgggcgg cattgcggtg
      121 gtgggcgaca acgccgagct cgccgagcag atggcgttcc tgcagaactc catcggtggc
      181 gtgcaaggcc cgttcgacag cttcctcgcg ctacgcggat tgaagacctt gccgctgcgc
      241 atgcgcgcgc actgcgaaaa tgccctggcg ctggcgcaat ggctggaaac gcaccccgcc
      301 atcgaaaagg tgatctaccc cggcctggcc tcgcacccgc agcatgtgct cgcgaaacgc
      361 cagatgtccg gcttcggcgg catcgtctcc atcgtcctca agggcggctt cgacgcagcc
      421 aagcgtttct gcgagaagac cgagctgttc accctggccg aatcgctcgg tggtgttgaa
      481 agcctggtga accatcccgc cgtcatgacg cacgcctcca tccccgttgc ccgccgcgag
      541 cagctcggca tcagcgatgc gctggtgcgg ttgagcgtgg gaatcgagga tcttggggat
      601 ttgcgtgggg atttggagcg ggcgttggtg aatcaaaatt gaggcgttta ttgttatatg
      661 gtgctgtatc tgttgctgga ggtagtttgt gctaaagaat ttttcaaata caaggcctac
      721 tacgataccg cggggaacca gtaattggcc gctagagcga gtggccacgg atgctgggga
      781 actttggttt ccggtagcag accaagtgat gcgcgagtat gcgcgcaata gtggtcgctg
      841 ggatccgcat gtcggtcagg tccttctgga gtgttgtgca agccataagg acggcttatt
      901 catcgatatt ggcgctaacg tcggttattt ctcgtgcctg ttgtctaagc actttccgag
      961 tctgaagacg tatgccttcg agccgcaacc gcttattcac gacgttcttg cgctcaatgc
     1021 ttggacttat ggtgcccgca tccagctcca ttcatgcgcg cttggatcca gtcgtggaca
     1081 gtggcgctga aacagcggtt aataatctag gtgacacccg tggtgtagaa ggaaattttg
     1141 cgagtactgt ggcgcctctc attagcctgg atgagctata tcctgatctg aacgcgagta
     1201 ttgtaaaaat tgatgtgcag ggtgccgaac tagacgtgat acgtggaatg gttggcgtca
     1261 ttcgtcgatc gccaagtatc aggattgttg tagagttcgg gcccgatctc gccgttgctg
     1321 agcattttgc gcccgatatg gtgttggatg tttatcgatc acttggcttt cgtattttgc
     1381 ttattagaaa tgggcagttg aacgaggcaa gcaacgcgga aattctgcgc tattgcagtt
     1441 ccgccggtcc catggcgcaa gcagatttgt tgctgctacg tgcttgatgc aagataaaat
     1501 acaaatacag gaaattcgaa aatggagaag gcagtaattg cagtaattgt taccggtgga
     1561 gccggcttca tcggatgcgc gctatctggc cagctcaaag catttggtct gccagtagtt
     1621 gcgatcgata atcttcatcc acagattcat gctgagtcca agcgaccaga ggtgcttgac
     1681 gaggcggcgc acctgcacat tggcgacgtt accgaagaaa acacctgggg ccaagtgctc
     1741 gaaaattggc agccgaccat tgtcgtccac ttggctgcgg agacagggac cggtcagtca
     1801 ttgaccgagg ccactcgtca tgcacacgta aacgtggtag gcaccaccgc aatgctagat
     1861 gcgttttccg cacgcaaact agttcctgaa catgttttgc ttgcgtctag ccgagctgtt
     1921 tacggtgaag gtgcatggtt ggatgcaaat ggcacaacct tttatccacc gccacgttcg
     1981 catgaagtgc tggcgcgttc acagtggaat ccactatcgc cgtctggtag gggggctgct
     2041 tccccgttgt cgcaccgacc ggatactgtt tttcctaatc ccactagcgt atatggagca
     2101 actaagcttg ctcaagaaca tattcttgct gcgtggtgtg gcgccatgca ggttccgctg
     2161 tcggtattcc ggcttcagaa tgtctatggc cccggccaat cgccattcaa ttcatacacg
     2221 ggtattatca cgctgtttca tcgtatggcg cggaaagccc agacgctaga aatttatgag
     2281 gatggcgaaa tcgggcgtga tttcgtcttt atcgatgatg tagtagtcgc cttgatggca
     2341 ggtctgcgtc agccacccgc tggctttcgt acgctagatg ttggtagcgg cgtcgttact
     2401 acgatcgccg aggctgcaaa gtcgatcgct gctatgcacg gtgcgccgga tccgcaaatc
     2461 agcgggaaat ttcgtgatgg cgatgtgcgc tgggcggtag cggatggtgc tcctctcgaa
     2521 cagtctcttg gtgtgcaggc tcgtataaat tttcaggaag gcgccaatcg tgtcggcgag
     2581 tggctgatcg ctcggggcta tgcatgaatt cgtttgacga gaaaacgcaa aaagaagagg
     2641 tgggcgttgt ctctgtggct gcgatgactg gtgctccacg ggattggata gactcagtgc
     2701 ggtcattgtt ggaactgaga ggcagctgcg agtgtgaaat cgttgcttgg gacaatgtca
     2761 gtgcttcccg cgattttaac ggcagtaagg cgcggatcag cgcggcttgg acattgtcgg
     2821 cagccgttac cgctatcatc agcgaacgct cctcaataga agctattttg atcgctgttt
     2881 cgcctgtgta gtgccggtgg aactcctaga tcgagcatta gaatggatgc accaatgacc
     2941 agcgtattgg gaccgtttcg tttctatcca atgctgctgg tgcactgagt tttccgcatc
     3001 gcaattcgcc gactccctat gggattcctg gaatggatga gtctggtgtc tgtagaacgc
     3061 ttcgtgatgc gtcgcctgac agtggcccgg tatcactaca ggttccagta ggtgcagtgg
     3121 tgttggtcaa tgcgcgcgta atcagagccg tcggtggatt cgatccggaa agcgactcca
     3181 atccttcaga atccttagcc gagttcgctc taaggacagc acgacgtggt tttaggcacg
     3241 tgcttgatgc gggctcttac gttactacac agtggagcag cgtcggagcc ccaactgaag
     3301 caagtgatga ccctcgatcg cgacagcgct tacatgcgca tgacggctct tttcctgcat
     3361 tgcacgatca tctacgttcg tcaaaagtag gcgctttggc aatcgcgctg gatgtcgcac
     3421 gtagcaagat tcaagggtta cgcgttctga ttgatggttc ctgcttgggt ccgatggaga
     3481 tgggaacaca ggtgcaaaca ttggcgctag ttcgctcact gctaaagcgt gacgatttag
     3541 tcgggtggtg cttgctggcc taatggaata ttacccgcat atgcgcgtga cctacttctg
     3601 aatcaaaact gactatctgc gatgccactg atctaatgtt tcatggagct gaacaggtct
     3661 atattttgca tcgtcctttc cagccagatc ggcagattcc ctgggagcgt tggcgtcaac
     3721 tgtccaaacg cattgttgtt accttgcagg atcttattgc ctatcgcgtc ggcagctatc
     3781 atgagacagg tcaacgttgg ctagaatatc ggaggaacat cgaaatcgcc gcaggtcgtt
     3841 ctgacgctat cgtggcgatc tctgatgaaa cttccgagtc gatcattgat gagcgttttg
     3901 gcggttgagt tccagcgaat ttatgtggtg aagaacggcg tgaccacctg actgatacag
     3961 atgtggagaa tgctccggca cctcgtcgaa aaggggctgg ttgccgcgca gtttttgttg
     4021 gtactgggtg cgagctatag ccataagaat cgtgacctgg ctatcctggc ttggaaagag
     4081 ttgcgtcgac gcggccacaa tatcgcctta gttatggctg gtgcagtggt cgccaaggga
     4141 agctctcggc aagaagaagc agtcgcccgc tggggcgctg acgaagagca acttgtaata
     4201 atgccagatg taagtagtgc ggtcaggaac tggttattgc ggcatgccag catcgtgttg
     4261 tatccaacct cagcggaagg cttcggcctc gtcccgtttg aggctgcttc tatgggaacc
     4321 ccaacggcgc atgtgagctt cggcccactt agggagctaa tagattcgcc agaacttcct
     4381 caggattggg atccgttgcg catggcggat cattgccagc agttattgca agatccccag
     4441 ttggccggaa aaaatatcaa gcgtgtcctt gctagcgggg ggcgcctcgt ttggagtgcg
     4501 actgcagccg atctgaccgt ggcgtaccgt caaacgcttg cgtccgcgcc gcgaaactaa
     4561 tatttccaga ggtttaaaat atgaatacga ctgaccttga tcaaatatcg cttgaacaag
     4621 cactcattga cttcgaagta gccaatgcac gcgtgatgga cctcacttcg cgtctgacct
     4681 ctatgagtcg ggagctgatc cagactcgat cggaattgga gcgcttacgt atcggtgcag
     4741 cgcccatttc gtactcagtc accaattttg agggctacga cgatgtccat aatcgttatg
     4801 cgcagatacc tgcatcgcgt ttggtgaagt ttgcttcgat gtttaacagt aagctgcgtc
     4861 ggtgtctgta atggaccgtc ctcgtattct tcattgcatc acggtgtata acgggggggc
     4921 attcgtacct gccgcaatca aaagtgcgct gcgcctagat cagccaggaa gcacaaatag
     4981 atgtataagt cctggatgac gcgagtcccg agcccggctg gagtgaggag ctgtctgcgt
     5041 tctgtaagga gcgtggcgta atgtattact gtactcctcg caacctcggt atcccgcgca
     5101 atgtcagtct aggaatgctg acggctgtta agcgaggtta cgactatgtc gtttattagt
     5161 aattcagatg ttctgtaccc ccgatactta atgggacaga tgttgcgagc gtcccgtctt
     5221 aaatattgtg gggttcggtg actgcttggt cgaacaacgt ttctctatat tcgttgccta
     5281 acaaacatcc taatcgttat ctgcatgatc agaatgtagt tgactggatg cctgccactt
     5341 tggcagtcat ctcggtgacc ggttatggat atccccgctg ttctcttttt gtacttgatt
     5401 tctactgatg ttgttcgcaa ggtgggaatc atggatccct gcttcgggcg tggctattgc
     5461 gaggagaccg attggagcct acgtagcctt gcagccggct atcggattgc gttggctcct
     5521 gggacttatg tttttcatca cggacgtgga tcgaatttgg atgcaggtct ggtttcctcg
     5581 aatgcaacga ccgtgcctgc aaatgaagcc atcatcgacc ttcgctatcc tcaatttcgc
     5641 aatcaggtag aagcgtttgt gcactcaggc gtgctttcgc gcgcgcatga tgatgcaatc
     5701 tctcatattg tgcggagtgc tggtaaacaa tttggctatt cgatagacgt gggttggatt
     5761 gggcgcgacc ggactaacga agacgaagtt aatattttgc tatcaccaaa cggtgctaat
     5821 gatcatatac aggcggtatt cagaggcttc aggctcgata tgcaggtgag tcgccggaac
     5881 ctgggacagg agatccccaa gtttttcggt caagacccaa ctgccggcaa tttgtatgat
     5941 tctggcgctc tcgctaccgc gttgaagtct gaattcgcaa tggtactaac acccgaacca
     6001 gtaattatcc tgagcgagta tagatactat gggttaatct gagttgggtc acccgaataa
     6061 taattttgat tttattcgca ttggtgccgt accagcgtgc tggtgagcca tcattttgct
     6121 ttggccaagc tgccagaacc actggtactt caattccaga ccttgggtgg ttatggggtc
     6181 tttattttct tttcgattag tggtttttta gttgcgcaga gttggcagcg tgatcctagt
     6241 cttgtccgtt tcacttatcg gcgattgctt cgtatctggc cgggtatgct ttgcgtcctt
     6301 attttgtgtg catttttact cgggccagct gttacgacgc tttctcttaa ggaatacttc
     6361 ttaaatgagt taacttggac ttatttcaaa accatgctgt ttcaagtgca gccatttttg
     6421 caaggtgtgt ttccagatag tgcggttcct tatattccca acggggtgct ttggactatt
     6481 ccaatagagg tgcattgcta tggctacctc gccattctag gagtaattgg tgtattgcgc
     6541 tggcgctggg tgcttctagc tgccacggca gccttagctg tttattacta tggctatcat
     6601 gacgctgaaa atgtattccg ggctggtggt ggaagagtac atgaaataga attcgccact
     6661 ttcttcttct ctggtgttct cttgcactac tttcgcgaga tatggtcgag ttggaatcga
     6721 attattccaa gttttttggt ggttatgaca gcatttttgc tgctttttca aaacgaccat
     6781 cagttgatcg cggttttctt gtttacgcct ttcttctttg tagtcttggg gaacttgtct
     6841 tttccaatta tgagaagatt cggccgcttc ggtgacatgt cctacggtat ttacatttat
     6901 gctttcccag tgcagcaaac tctattttgg ctttggggtg aaagtatttc gtttaataca
     6961 agcctcgcgc tagcactcac gattactggg ctattggcct ggatttcttg gcatcttatc
     7021 gagcagcctg ccttgcggct aaagccacgt actccaaaaa ggattatggc cggtgagtaa
     7081 ttgcgtcttc cattagttcc actgtgttac aaataatcgt atctttgtgc cactattgga
     7141 agaccttcag gccgcgtggg agagctgtgt tgaataggtc actggaagtg cgttttgaac
     7201 agtacgggga agtagttgct gccgccctgt cccatgcgga tcgcaaacag cccgcacact
     7261 ggtacctgaa agggttgcta ctgcctggag ggcgcaagag cgtggagccc atggccgcgc
     7321 gggtgcaccc gcagaacgtg ggctcagccc atcaatcgat gcaccatctg gtggccgatg
     7381 ccgactggag cgatcaagcg ctgctggcgg cggtggcggc acaggtgctg ccgcccctga
     7441 gcaggaagag cgcagcgtgt cactggatcg tggacgacac gggattttca aagaaggggg
     7501 tgcattcggt cggtgttgca cgccagtact gcggccgcct tggcaagacg gacaattgcc
     7561 aggttgccgt gagtttgtcg atcgccaacg aacacggcag cctgccagtg ggctatcggc
     7621 tgtatcttcc cgagcagtgg gctcaggaca ctgtgcggcg caagaaggca ggcgttccgg
     7681 atcaggtcgt gtttcagacc aagacagcgc tggccatgga tcagatcgac agcgcgctgg
     7741 cgacagggat tgcggcaggc gtcgtgctag ccgatgcggc ctacggcacc gagacccact
     7801 ggcgagacca gctcagcgaa cgcggcctgc tgtacatggt tggcgtccgc agcaacacga
     7861 aggtctggtg gggatcgcac caacctgcgc ccatgccgcc agccagccct aagggcggtc
     7921 ggccccgcac acgaccgatg cgcgatagcg cacatgcgcc gatctcggta catgaagtcg
     7981 cgcagcgctt gcccgcaagg acgtatcggc aggtcagctg gcgccagggc agcgacgcaa
     8041 cgctcagttc gcggttcgcg gcggtgcggg ttcgtgccgc acacaatcgc caggcacatg
     8101 acgagcagtg gctgctgatc gagtggccgc cgggagagtc cgagccccgc cactactggt
     8161 tctcgacgct accaaagcaa acgctggtca agacactggt tgccacggca caaggccgat
     8221 ggcggattga acgcgattat caggagctga agtcggagtt gggcctgcat cactatgaag
     8281 ggcgcaactg gcgtggtttt caccatcacg ccagtctgtg catcgccgca tacgggttct
     8341 tgatgcgcga gcgcctgcgc agtaaaaaaa actccgtcgc attcaagatg cctgcagtat
     8401 ccaaaagcgt ccgcccgcgc cggtctggcc ccaatgcaac gtcaccatcc caactcgatt
     8461 gccacgctgg acttcggact ggctaggctt atcgccagaa gcctcccaca ctgcccgtgt
     8521 tgcggggtct caccgtacca acggattcgt atttagtaac acagtagaat tagtagtcgc
     8581 ccctgaaaaa cccccagacc acatccattg caaggcttca tctgcgttat cggtgtgctg
     8641 gaattgccag ttttcgttac gctacgtcct ggtttctggc agttttcgcc catgcgtaca
     8701 cgccgtcctg ccggagtctg taaattgaac tgtgtaactg ccctttgaca agcgactggc
     8761 ccggaccgga gaggagcagg caagtggaac tggataagac gatgctggac gaactgacgt
     8821 caggctgcaa gacgccacag gacgttgaga agctgttttc gcaaatgttg cagcacatga
     8881 tcaatcgctc gttggaggcg gagatgcaag cccatgtggg ccatgcgccg catgggcgct
     8941 caggcggcaa cgtgcgcaat ggcaagagcc gcaagacggt gcaaagcgcg ttgggcgagt
     9001 tgcagatcga gaccccgcgc gaccgcgcgg gcacgttcgc gccacagttg gtgaagaagc
     9061 gccaggtgcg gctggcgggg atggaggaga agattctggc gttgtacgcg cgcggcatga
     9121 ccacgcgcga catcgagtct gcgctggtgg acgtgtatgg ggtggagata tcgcatgggt
     9181 tgatcgcaca ggtgaccgac gcggtgctgg aggaggcgcg ggcatggcaa tcgaggccgc
     9241 tggaggcgat ctatccgatc gtgtggctgg acggcatcgt ggtgaaggtg cagcacaaca
     9301 agcaggtcat caacaaggcc gcgcacgtgg tgctgggggt caacctgcgc ggggagaagg
     9361 aagtgcttgg cctgtggttg gctgaacacg agggcgccca atactggctg tcggtgttga
     9421 ccgaactgcg tcatcgcggc gtgcgcgaca tctacatcgc ctgcatggat ggcttgaagg
     9481 gcctgcccga agcggtgcaa gcggtgtttc cgcagacgct cacgcaactg tgcattgtgc
     9541 atttggtgcg ggccagtctg cgctacgtca acgcaggcga cagcaaggcg gttgtggctg
     9601 cgctcaagcg catctatcag tcggccacgg cggaagaagc ggcggcggaa ctggaggcgc
     9661 tggacacgca gtggggcgac aaataccgtg cggtggtccg cttgtggcgg ggcaactggg
     9721 acaacatcat cccgttcttc cagttcgtgc cgcagatccg caaggtgatc tacaccacca
     9781 atgccatcga atcgttgaac atggtcatgc gcaagctcac ccgcaaccgg cgtattttcc
     9841 ccaacgacga ttcggcgctc aaatcgttgt ttttggccgt gcgcgaggca tcgaagaact
     9901 ggcggtccat ccatcactgg aaaccggctc tgcaaagctt ccaggtgatg ttcggcgaag
     9961 aacgcgtgcc gatgaatgcg ctatgaaaaa cctggttaca cagttggctt gacagaccct
    10021 cctgcctgcc cgccgagcag ttgcctgccg atgagctgtt tcgttcgcgt ctggagaacc
    10081 agatcgactt gcgccatccc ctggtgcaga tcctgcatcg cggccaagcc aaggcgctga
    10141 cacggcggca atggcgctgg atcaaacgac ggcaagcggt agagccggtg atcggacatt
    10201 tgaaacagga ctgccgcttg aatcgctgcc atctcaaagg cgcccaaggc gatgcactgc
    10261 acgtgctcgg ctgcgccgct ggcgacaacc tgcgctggct gctgcgctgg atcgcatttt
    10321 tgcgtgcctg gttgcaggtg gtgcgggcgc gttcctcaac gcactcaagc accatctggc
    10381 ccacaaacat ggcactggag gtttgagagg ggtttttcag gggcgactag ctgctgagag
    10441 ggcgttgcac ttggaaattg agtctaacgt tttttcaggg gcgactactt gctcataacg
    10501 tcatcactcg gggagtcagg tgctgtttga gtagcggaca gaaacagata ggggttgggc
    10561 acctgagatt ccgtggacca actgcgaatt aatcgcggta agtacgattg catcgtgtag
    10621 ccaatggtgc tgaacatgat catcaccagg tccctcagcc agtgcaacgt cgaggctata
    10681 ctcaccccga attagccgtg ggagacgtag ctggaaggtt acagttagca ccgagccctc
    10741 ctggatgctt atagcctcct cgcgcaggta gctatcggag ctttctgcca agatgtactg
    10801 accttttctg ttcttaagca taaagcccac agcaggatag ctgagtgact tgtttagtcg
    10861 tgcaactact gtaaggcgaa tgtcttcgga ggagttgaac tcgacgagcg gatcgccgag
    10921 catgttgtgg aaagcaactg attcgatgcg agcgccgcca gccccgaaac catcggcgtt
    10981 ggaacgaaat ggactagcat ggaatcgagt tgcttcaata ttcttactat cgtaggttgc
    11041 ttggataggg tgggaggctc gcgtaacggc tgaagttgtg cgatcagaat ataagtcgcg
    11101 caggtagact gcagaaatat cccgtgcact tccaacatcg caaagatagt gctcgcctcg
    11161 gcggcgcaag agtactgccg attcgcacaa agcatttaaa gctcccatgt cgtggctgac
    11221 aaatagaagc gtcccgcctt ggcgttgaaa gtttgccaaa aaccgcatgc atttttgttg
    11281 aaagtatgca tctccaacgc tcaaggcttc gtcaatcaca aggatttcag catcaacatg
    11341 cgcgattagc gcgaaagcaa ggcgcacgta catgccgcta gagtaagttt taaccggctg
    11401 ctctataaat tcgccaatgt cggcgaaagt tgcgattgat tccatgcgca tgctgatggt
    11461 tttcttatcc acaccataca gcgaggcggc taggtaaata ttttcacggc cggagaactc
    11521 tggattaaag cctgcaccta attccaatag cgcagcaact cggccgttca ctgtgatctg
    11581 accctcagta ggagttaggg ttccgcagat catctgtagt aacgtcgatt ttcctgcgcc
    11641 gttgcgaccg ataatgccga cggtttcgcc gcggcggata ctaaagctta cttggcgcag
    11701 cgcccagaac tcacggtagt aacgacggcg accacgccag agcatttgca tcaagcggtg
    11761 tgcaggcttg tcatagacgt taaagcactt gcccagacct tttacttcga tagcgatgtc
    11821 agagcacatc ggcaaacccc tttcgggtcc tctgaaagaa tgcgaagccg gtaatgaaaa
    11881 ctaaagcaga tattactaag cagagagaat actcaagggg tttcaggcca tggccccaaa
    11941 tcaatacatt acgtatctgc gcaataactg gcgccagagg gttgatgtta aggatagggc
    12001 ggaaagttgg agggatggcg tcgattggat aaaatatcgg cgttaaaaac attatggctg
    12061 tagtgataat ggcggtgatt tgagcaatat cacgcaaaaa tacgcccagc gcagagagta
    12121 gccatgctaa ccccatcata aacaaaacta acggcagaat tgctagcggc agcaaaagcg
    12181 ccgtcactgg cggcactcca taagatgcga ggtaaaatac caacaatacc atcaggttga
    12241 caatcagtcc gaacattgcg gtcaacacgc tgacaactgg caggacttcg agtgggaaga
    12301 ctactttttt cacgtaatta gcattgccaa taatcaattg aggtgcgcgg ttaaatactt
    12361 ccgaaaacag attaaagaca agcagaccgc taaataatac aagtgcaaat tcggtttttg
    12421 ttccactccc gccaagccag cgggccttaa atacttcgct gaacacgaag gtgtagatcg
    12481 caagcataaa gatgggttga attagcgccc acgtgaaacc aagtagcgaa ccacgataac
    12541 gcgctgatat ctcgcgaacc gccagtgcac tgatgagcct tcgattagcg atgaggctct
    12601 gaaggagact gctaggtgaa ccggagtagg gttccatcag taagctgcgt atggatgact
    12661 ttctagtcta atgcgggttt atgattcttg tctgctaaat cggagctcgc tggcgccagc
    12721 gagccacaat ttagtcgatg ttcaggtgga gcttggaatg tcacaaatcc aggctgcgtg
    12781 gtgttctact gtgcgtagct gcttaggcga ttaaaagagg cggtaactaa tccgctcagc
    12841 aaacgcggtg atgcgggagt tacagcactt tttcaagctc cggcagcagc gtaaacaagt
    12901 cccccaccag cccgatatcg gcaatctcaa agatcggcga ctccgggtcc ttgttgatcg
    12961 ccacgatcgt gccggcgtcc ttgatgccgg tcagatgctg tatggcgcca ctgatgccga
    13021 tggccatgta cagctcaggg gcgatgatct tgccggtctg gccgacctgc agttcgttgg
    13081 gcacgtaacc ggcatcgacc gcagcgcgcg aggcacccac ggcagcgcca agtttgtcgg
    13141 ccaggctgta gatgtgcttg aagttttctg ccgaacccac cccgcgg
//
