LOCUS       BGC0000792             18817 bp    DNA     linear   BCT 25-JUL-2016
DEFINITION  Enterococcus faecalis strain OG1RF polysaccharide biosynthetic gene
            cluster, partial sequence.
ACCESSION   BGC0000792
VERSION     BGC0000792
KEYWORDS    .
SOURCE      Enterococcus faecalis OG1RF
  ORGANISM  Enterococcus faecalis OG1RF
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
COMMENT     ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 20:35:45
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 18817
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..18817
                     /db_xref="taxon:474186"
                     /mol_type="genomic DNA"
                     /organism="Enterococcus faecalis OG1RF"
                     /strain="OG1RF"
     subregion       1..18817
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Saccharide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..18817
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     CDS             778..1314
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172:methionine aminopeptidase (Score: 173.5; E-value:
                     1.1e-52)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde1; similar to Synechocystis sp. methionine
                     aminopeptidase A"
                     /product="methionine aminopeptidase A"
                     /protein_id="AAC35914.1"
                     /transl_table=11
                     /translation="MITLKSPREIEMMDESGELLADVHRHLRTFIKPGITSWDIEVFVR
                     DFIESHGGVAAQIGYEGYKYATCCSINDEICHGFPRKKVLKDGDLIKVDMCVDLKGAIS
                     DSCWSYVVGESTPEIDRLMEVTKKALYLGIEQAQVGNRIGDIGHAIQTYVEGEGYGVVR
                     DFVGHGIGPTIHEVQ"
     CDS             1558..2466
                     /codon_start=1
                     /note="similar to Bordetella pertussis serum resistance
                     locus BrkB"
                     /product="Orfde2"
                     /protein_id="AAC35915.1"
                     /transl_table=11
                     /translation="MKFXDNIKKNQSLMRFIETTQSHMVTAEIGNSSVVVAYYLLLSLF
                     PLLIAVGNVLPYLRIDPNSVLPYIAEAIPKDVYKNLEPAIRSLLTQRSGGLLSVSALAA
                     FWSASQSINALQNAMNKAFGVEQRKNFILVRVVSFLVILLFMVAIVGVVVILGLGQYII
                     ELLQPIFHYSTSVIDTFQALKWPLTTVVLLVIMCLIYAVVPNRKLSLRSILPGAIFSTV
                     GWMLLSQIFGLYVKYFSSRIASYQIIGSFIILMLWLNFAATIIILGAIVNAVVDEYLXG
                     XKEKKQPSFEQRLFRWFKKKX"
     CDS             2718..3710
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_4"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to Bacillus subtilis undecaprenyl-phosphate
                     N-acetylglucosaminyltransferase"
                     /product="Orfde3"
                     /protein_id="AAC35916.1"
                     /sec_met_domain="Glycos_transf_4 (E-value: 4.9e-38,
                     bitscore: 120.8, seeds: 116, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTAGGLAIYIAFASSCLLIFRSIIPQDYIWPIILAGGMVVLTGL
                     IDDIKEITPMKKTIGILLAALVIYFVAGIRIDFVTLPVVGMIDLRWFSLPLTLLWILAI
                     TNAVNLIDGLDGLASGVSIIGLTTIGITGYFFLHAKTVYIPIVIFILVASIAGFFPYNF
                     YPAKIFLGDTGALFLGFMIAVMSLQGLKNATFITVITPMVILGVPITDTVYAIIRRLLN
                     KKPISSADKMHLHHRLLSLGFTHKGAVMTIYALALVFSFVSLLFSYSSTVASILLIVFC
                     LIGLELFIELIGLVGEGHQPLMYLLRILGNREYRQEQMKKRLGKHSKRK"
     CDS             3831..4670
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde4"
                     /product="putative glycosyl transferase"
                     /protein_id="AAC35917.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.3e-19,
                     bitscore: 58.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSMQEMVTISIVTYNSRYIFNVLDQLKAELGTDSIYDIHIYDNHS
                     ETAYLEKLTTYEPFITIHRAEENQGFGHGHNQVLFNASTKYAIIFNPDVLVTKDVLDRL
                     LDRIKIDKNIAVVSPKVLNEDGTTQYLVRQKLDVFDYMLRFIPFQFVKKIFDKRLSIYE
                     CRDLSDTETTDIKMGSGCFMLIDREKFVEIGGFDERFFMYFEDNDLCLRFGKAGYRILY
                     TPFETVVHMYEKGAHKSVNCLKSLCNQWGNFLTNGAGGSFNESKISGSHRLISNENG"
     CDS             4597..5445
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde5"
                     /product="putative glycosyl transferase"
                     /protein_id="AAC35918.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.5e-09,
                     bitscore: 28.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLEVLLMSQRLAVVIVLYQMKMADTPNYLLLKEVVDHPELHLFI
                     YDNSPLPQEDALFLQQNVTYRHNPDNPGLATAYNEAIAFSQANQCELLLLLDQDTEVPA
                     SYFDTLIIMSLDPTVAVYVPIVEANGQQISPVYSDQYVGLKGAKPTAGIANQPLMAINS
                     GTVITAETLRWLEGFSEEFPLDYLDHWFFYQLNQANKKIEVLPVHLKQELSVLDYRTMS
                     SQRYRSIIEAETLFYRRYDQEKFSHHRRHLFLRSSKQFLTVKNRQIWRQTLAEFLKLMK
                     G"
     CDS             5577..6161
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde5_6"
                     /product="putative glycosyl transferase"
                     /protein_id="AAC35919.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.8e-15,
                     bitscore: 46.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEILRTYAANYPQIQLLQGPGQGVIANFAFALTHTKGEVIFLADQ
                     DDVWLPNKVTTVTEYFETHPDIQVVISDLKIVDADLQVTNPSYFKFRKVKPGFWRNAIK
                     SGYIGAGMAFRQEMKNVILPIPPEVPMHDMWIGLLAARKKQTGLIKEPLVLYRRHGANV
                     SPIITKTSFQQKLNWRVNLLKALHQRLKEQR"
     CDS             6283..7149
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 292.7; E-value:
                     4.8e-89)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde6"
                     /product="putative glucose-1-phosphate thymidyl
                     transferase"
                     /protein_id="AAC35920.1"
                     /transl_table=11
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLAG
                     INEILIISTPEDTPRFESLFGDGHDLGIHIEYAVQESPDGLAQAFIIGEEFIGDDSVCL
                     VLGDNIYYGGGLSKMLQRAASKESGATVFGYHVNDPERFGVVEFDEEMRALSIEEKPAQ
                     PKSNYAVTGLYFYDNEVVEIAKGIKPSERGELEITDVNKVYLEKNKLSVEVMGRGFAWL
                     DTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYITKEQLVELAQPLKKNGYGQY
                     LLRLAAE"
     CDS             7162..7734
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde7"
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="AAC35921.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 2.8e-72,
                     bitscore: 232.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVIDTXFQDVKIIEMDVFGDHRGFFTESYSKAKFAEHGLDFDFV
                     QDNHSLSTEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVIVDIRKGSPTYGQWEGYILS
                     EHNHRQLLVPKGFAHGFVTLTPNVNFMYKCDNYYNAAADGGIAFNDPALAIDWPIAPEK
                     AITSEKDQKHPTLKEFEAENPFIYGEI"
     CDS             7759..8787
                     /NRPS_PKS="Domain: NAD_binding_4 (5-197). E-value: 5.3e-18.
                     Score: 56.8. Matches aSDomain:
                     nrpspksdomains_AAC35922.1_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     253.2; E-value: 6.4e-77)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde8"
                     /product="putative dTDP-glucose-4,6-dehydratase"
                     /protein_id="AAC35922.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.6e-18, bitscore:
                     56.8, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 8.7e-15,
                     bitscore: 44.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.4e-14, bitscore:
                     42.0, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIIVTGGAGFIGSNFVHYVVKNHPEVHVTVLDKLTYAGNEKNL
                     EGIPSDRVELVVGDIVDAELVNRLVAETDAVVHYAXESHNDNSLNDPFPFVQTNLIGTY
                     TLIEACRKNNVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSSTKA
                     GSDLLVKAWVRSFNLQATISNCSNNYGPYQHIEKFIPRQITNVLSGITPKLYGAGKNVR
                     DWIHTNDHSSAVWAILTKGQIGETYLIGADGEEDNKTVMELILELMGQPVDAYEHVNDR
                     VGHDLRYAIDSTRLREELGWEPEFTNFREGLAETIKWYTENEDWWRADKEAVEAKYAQN
                     GQ"
     aSDomain        7774..8349
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAC35922.1_NAD_binding_4.1"
                     /evalue="5.30E-18"
                     /label="AAC35922.1_NAD_binding_4.1"
                     /locus_tag="AAC35922.1"
                     /protein_end="197"
                     /protein_start="5"
                     /score="56.8"
                     /tool="antismash"
                     /translation="VTGGAGFIGSNFVHYVVKNHPEVHVTVLDKLTYAGNEKNLEGIPS
                     DRVELVVGDIVDAELVNRLVAETDAVVHYAXESHNDNSLNDPFPFVQTNLIGTYTLIEA
                     CRKNNVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSSTKAGSDLL
                     VKAWVRSFNLQATISNCSNNYGPYQHIEK"
     CDS             8823..9722
                     /NRPS_PKS="Domain: NAD_binding_4 (42-221). E-value:
                     4.4e-16. Score: 50.6. Matches aSDomain:
                     nrpspksdomains_AAC35923.1_NAD_binding_4.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 95.8;
                     E-value: 5.5e-29)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde9"
                     /product="putative dTDP-4-keto-L-rhamnose reductase"
                     /protein_id="AAC35923.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.3e-16, bitscore:
                     50.6, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.1e-11,
                     bitscore: 34.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.9e-115,
                     bitscore: 373.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKYKSYFALPFFQEGAKKMILITGGNGQLGTELRHLLDEQGIEY
                     VSTDSTELDITDADSTLAKVKEIQPSVIYHCAAYTAVDKAEDEGKELDEKVNVDGTRHV
                     AEAAKAVGATLVYVSTDYIFDGTKKEGVYAIDDQPNPLNEYGRTKLLGEQAVQEILDDY
                     YIIRTSWVFGQYGHNFVFTMQKLAETRDQLTVVDDQFGRPTWTRTLAEFMAFVIAEKAP
                     FGVYHLSNENSCSWYQFAKEILKDTEVEVLPVDSTQFPQKAQRPQYSVMDLSKTEALGF
                     KIPTWQEALAQMLENVQQ"
     aSDomain        8949..9485
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AAC35923.1_NAD_binding_4.1"
                     /evalue="4.40E-16"
                     /label="AAC35923.1_NAD_binding_4.1"
                     /locus_tag="AAC35923.1"
                     /protein_end="221"
                     /protein_start="42"
                     /score="50.6"
                     /tool="antismash"
                     /translation="IEYVSTDSTELDITDADSTLAKVKEIQPSVIYHCAAYTAVDKAED
                     EGKELDEKVNVDGTRHVAEAAKAVGATLVYVSTDYIFDGTKKEGVYAIDDQPNPLNEYG
                     RTKLLGEQAVQEILDDYYIIRTSWVFGQYGHNFVFTMQKLAETRDQLTVVDDQFGRPTW
                     TRTLAEFMAFVIAEKA"
     CDS             9781..10506
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 81; E-value: 1.7e-24)"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde10"
                     /product="putative glycosyl transferase"
                     /protein_id="AAC35924.2"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5e-23, bitscore:
                     72.0, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVLLIIPAYNEEENILRTIASIETFKQEVTHFQHELDYVVINDG
                     STDGTKQILEVNQINAIHLVLNLGIGGAVQTGYKYALENEYDVAXQFDGDGXHDIXSLP
                     ILLEPLAEGXCXFSXGSRFIPGNZASFQSXKMRRXGIRLLSFCXXXAXGXTIYXVTXGX
                     RAGNRKVIAFFAKRYPTNYPEPESIVHLIKKRFVIVERPVNMMERLGGVSSIRALASVK
                     YMLEVGSAILIAPFMKEGD"
     CDS             11518..12312
                     /codon_start=1
                     /note="Orfde11"
                     /product="putative ABC transporter permease"
                     /protein_id="AAC35925.1"
                     /transl_table=11
                     /translation="MFKETFSIFKNIFQNKKLLLQFSFNDFKAKYAGSALGIVWAFLTP
                     LVTVLTYWFVFSVGLRSRAGDNMPFIVYLVTGMVPWFFFSDSLLSATNVFREYSYLVKK
                     VVFNVQILPTSKILSNLYTHLFFIXIGFVITTANGXYPSLYSLQLIYYLACLLVFLTAI
                     TWITASTQPFLPDIMQFINIIMQTVMWTLPILWQPTGMIATILKINPLYYIVQGYRESY
                     LGGAWFWEHWQYSLYFWGVTIVLLLIGSTVFRRLKPHFSDVL"
     CDS             12325..13005
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 136.3; E-value:
                     2.2e-41)"
                     /gene_kind="transport"
                     /note="Orfde12"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="AAC35926.1"
                     /transl_table=11
                     /translation="MSEYAIDIQHITKTYNMYKKPSDRFKEALSPTKKSYHDLFYALDD
                     VTMQIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGSMVINGKISALLELGSGFNPEY
                     SGYENIFLNGMVLGFSREEMEERVQDVIDFADIGDHLYQPVKTYSSGMFVRLAFAVAIN
                     VDPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDVNSIRRFCDRTFWVAT
                     RESP"
     CDS             13019..13543
                     /codon_start=1
                     /note="hypothetical protein"
                     /product="Orfde13"
                     /protein_id="AAC35927.1"
                     /transl_table=11
                     /translation="MDVTTNYENFLEKKSIKTGDREATMKDETPTPDIIEVDHAELLNA
                     DYEPLEMVTQDEKVIVKIEYTVKNDQIKKPVCGVAIRTVDNHYVCGLNTLLDGVQIPWK
                     KGRNVFYLEYEKMSLLTGEYYFDIAFFEEHATVPLVYKTKYVTMFITGRYAGEGIVILD
                     HKWKDTTKDEV"
     CDS             13533..14714
                     /codon_start=1
                     /note="hypothetical protein"
                     /product="Orfde14"
                     /protein_id="AAC35928.1"
                     /transl_table=11
                     /translation="MKYDFEMETDESTSVGKIVAQIKENSDVLEFGPGNGRMTSYLMEE
                     KKCQVSIVELDKELYDHVSQFSTDAFYGNIDENDWVEYFAGKTFDYIVFADVLEHLMNP
                     QSALAKVKPFFKPGGQILITFPNLAHNSVLIDLFNNRLTWNETGLLDATHKSFYLQEGF
                     EKVFVEVGLYIAKEDFTFNQVGYNEIPTTYEALPVEVQAAFKARPFGEVYQYFFALTAE
                     PVEQPERVTPVNSYNEKNVHILINCGEEKETELDQPVDLQKPETKQFQLKIPEDVQLIK
                     LFPSLTGAIIKLSMTIDGETVPVAATNAFLVQENIYYFLDTQVPVIEVTDAQMAGKDLT
                     VDIDYFFEGNYSERENTFIHALLDERNQFLEEMNKQTEIAHMHTGKYKRNHVX"
     CDS             14936..16543
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde15"
                     /product="putative glycosyl transferase"
                     /protein_id="AAC35929.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 7.2e-36,
                     bitscore: 113.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVLSLRFKDPEDLPAYTLNIDTKSGQKVQYVVERPNMVQPGTKFD
                     RAWRSIQTRGLMGSVKWYFKRQEKAEAPVDVEAVLAEIKTFQFQPKISVAVPVYNVEEK
                     WLAACVSSLQNQYYENWELCLADDASPSEHIKPMLEKYKELDQRIKVIYREENGHISEA
                     TNSALSIATGDFVGFMDNDDELAPQALYEVVKALNTDPTIDFLYTDEDKITENGRRFNA
                     FYKSDWNPELILNHNYITHFVVVKRDLLEKVGGLNSAYNGAQDYDFVLRATEQATKIKH
                     IPGMMYHWRAIESSTALNPESKGYAYVAGQKAVQAATERRGLKAQVEIAEFYGSYKINY
                     LYDHVPMVSLIITNDTENMSSYLRQLLEKTAYTNYEILLPARFENQINIQNDRLRYVST
                     ETRHGMIQAAKGEYVALLNAGLVPTKNDWLKELMNIGQQETSGLVTGRVVDARDRVETV
                     GVSVDTDKGRLLYPEKGTPGKSLGYYYRIALPRNIQAATEDCLLFNKQLYLNLEGINES
                     LGKEWMGVDLSLQFASAW"
     CDS             16700..>18817
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /note="Orfde16"
                     /product="putative glycosyl transferase"
                     /protein_id="AAC35930.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.7e-32,
                     bitscore: 102.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEDIKVIFDSIYRDKTTNNLTITGWALDTITKESPTFTINNENQ
                     VSAYNIQRVLREDVNQIYQTEPAIEAGFVVTLEGIKQKKVLPFHFQSSAHVVTVDFPLN
                     KKYPVIPGTEDKVTRLWIKAKKGFKYMAKNGISHTIQRAKIEKLRNQASYPNWLARNEV
                     LDIEAMTQEIATFHYQPKISIAMPVYNVEEKWLRLCIDSILNQVYTNWELCMADDASTD
                     PNVKKILTEYQQLDERIRVVFREQNGHISEATNSALAIATGEFVALLDNDDELAINAFY
                     EVVKVLNENPELDLIYSDEDKIDMDGNRSDPAFKPDWSPDLLLGTNYISHLGVYRRSIL
                     EEIGGFRKGYEGSQDYDLVLRFTEKTTKERITHIPKVLYYWRMLPTSTAVDQGSKGYAF
                     EAGLRAVQDALVRRGINGHATHGAANGLYDVYYDIESEKLVSIIIPTKNGYKDVQRCVS
                     SIIEKTTYQNYEIIMADNGSTDPKMHELYAEFEQQLPGRFFVESIDIPFNFSTINNRAA
                     KKAHGEYLLFLNNDTEVITENWLTLMVSFAQQERIGCVGAKLLYPNNTVQHAGVILGLG
                     GVAGHGHYGYPHGDLGYFGRLAINVNYSAVTAACLLMKKADFDAVGGFEEAFTVAFNDV
                     DLCLKVQALGRDNVWLHEAELYHFESQTRGYDDKGKKKKRFEQEKVMMEEKWGPLIEND
                     PFYNPNLTRDIP"
ORIGIN
        1 angntcccnt aanntctttn ggntnacttt tgnggcagnc nttaantncc ggtatnntat
       61 ttttaatttt ggatttccaa aacnccnggg gaaaatttgg gacntagcca tttttttnnt
      121 ggtgtttanc ttatttattt caacgtaagt tattctgcgg gcagttgnnt aatttttttc
      181 gcaaattctt tctaaaacgt tgggatgtcg tcttntttca gcgggntaaa tcaactttaa
      241 cgctgtcggc gccttttttt gccccaattt cagtaaagga ctgcttcgaa gtcgtccacc
      301 gatttacaaa aatcatcata aaacgtgtct cctgaaccca caaacgccga agatttttcc
      361 tgataaatca atctcttgta agtcttcata aaagtcgaca atttcatcag gtaaatcgcc
      421 atcgccatac gtatatgtag ctactacaca gatatcggcc tcttcaaaat cagcggcatc
      481 gacttgcgta cactcatcaa tttcgacctc taattctaaa tcttcaaatg cttctgcaac
      541 aatgtcggca atttcttctg tattcccagt catgcttgca tacacaattt tagctaacgt
      601 cataaacttt cttccccctc atacaattct gtcacttatt atagcagatg cgcatttctt
      661 ataaaagact agcgagtgct tttattaagg gactttttga aaattggtgt ttgaacaatc
      721 ttttttgcaa aaaatgtgat aaaataattt gaatgaaaca agtttaggag agatagtatg
      781 attacattaa aatcaccacg agaaattgaa atgatggatg aatcagggga attattagcg
      841 gatgttcacc gtcatttacg gacgtttatt aaacctggca ttacaagctg ggatattgaa
      901 gtatttgtga gagactttat tgaaagtcat ggtggcgtgg cggctcaaat tggctatgaa
      961 ggttacaaat atgctacctg ttgtagtatc aacgacgaaa tttgccacgg atttcctcgt
     1021 aaaaaagtat taaaagatgg cgacctaatc aaagtagata tgtgtgtcga cttaaagggc
     1081 gcaatctctg attcatgctg gtcttatgtc gtgggtgaat caacacctga aattgatcgc
     1141 ttgatggaag taaccaaaaa agcgctatat cttgggattg aacaagcaca agtaggaaat
     1201 agaattggcg atattggtca tgcaattcaa acgtatgtag aaggagaagg ctacggggta
     1261 gttcgcgact ttgtaggtca tggcattggc ccaactatcc atgaagtcca atgattcctc
     1321 actatggtga agcaggtaaa ggactacgtt taaaagaggg aatggttatt accattgagc
     1381 caatggttaa cacaggaact tggcgcatga aaatggaccc aaatggttgg actgcttata
     1441 ctgaagatgg cgttctaagt tgtcaatatg aacattcatt agcgattacg aaagaaggtc
     1501 ccaagaatct taacgtcaca aggcgaagaa ttgacttatt aataaggaga gtgtgtgatg
     1561 aagtttntcg acaacatcaa aaagaatcaa tctttgatgc gttttattga gacaacgcaa
     1621 agtcacatgg tcacagccga aataggcaac agctcagtgg ttgttgccta ttatttatta
     1681 ctctcgctgt ttccattact gattgcggta ggtaatgtct taccttattt aagaatcgac
     1741 cctaattctg tgttgcctta tattgcagag gcgattccga aagatgttta taagaactta
     1801 gaaccagcga ttcgttcact actaactcaa cgttcaggcg ggttgctttc tgtttccgct
     1861 ttagcagcat tttggagtgc cagtcaaagt attaatgcac tacaaaatgc gatgaataaa
     1921 gcttttggtg tcgaacaaag gaaaaatttt attctcgtaa gagtggtctc atttttagtt
     1981 attttgttat ttatggtagc gattgttggt gtagtagtaa ttttaggtct gggtcagtac
     2041 attattgaat tactacaacc aattttccat tactcaacgt ctgtgatcga tactttccaa
     2101 gcgttaaaat ggccgttaac gaccgttgtt ttattagtga ttatgtgttt gatttatgcg
     2161 gtcgttccta atcggaaatt atcgttacgt tctattttgc caggggctat tttttcgaca
     2221 gtcggttgga tgctattatc acaaattttt ggtttgtacg taaaatattt tagttctaga
     2281 atcgcaagtt atcaaatcat cgggagtttt atcatcttga tgttatggct gaattttgct
     2341 gccacgatta ttattttagg agcaattgtc aacgctgtcg tcgatgaata cttatntggn
     2401 gntaaagaaa aaaaacaacc aagttttgaa caacgcttgt ttagatggtt taaaaagaaa
     2461 aantaaatgg atttctttaa aaaagtctaa accgttgccc agaacacatg tttcagcttg
     2521 taaatgcttc agtttacggt ataatatacc ctgaacgaga agaaagtggg ttcgactatg
     2581 tcactattta tttagaagtt tgatacgttt attatgacat ttatctatct ttgctattaa
     2641 caccacttgt taagcttcta gcgtttcgga ttggcgccta tgatgcacca ggagagcgac
     2701 gaatcaatac caaaaatatg cctacagcag gaggacttgc aatctacatt gcttttgcta
     2761 gttcatgttt attgattttt cgttcgatta tcccacaaga ttatatttgg ccgattattt
     2821 tggctggtgg aatggttgtt ttgacaggcc tcattgatga tattaaagag attactccaa
     2881 tgaaaaaaac aatcggtatt ttgttagcag cattagttat ttattttgtt gctggaattc
     2941 ggatagattt tgtgacgttg ccagttgttg gaatgattga tttgcgctgg tttagtttac
     3001 cactaacttt attgtggatt ttagcgatta cgaatgcagt aaatttaatt gatggtttgg
     3061 atggtttagc atcaggcgta tccattattg gattaaccac gattggtatt acagggtatt
     3121 ttttcctaca tgctaaaacg gtctatattc caattgttat ttttatttta gttgcgagca
     3181 ttgcgggatt tttcccatac aatttttatc cagctaaaat atttctagga gataccgggg
     3241 cgttattcct cgggtttatg attgcagtaa tgtcgttaca gggcttaaaa aatgctacgt
     3301 ttatcacggt aattacgcca atggtgattt taggtgtgcc aattacggat acggtttatg
     3361 caattattcg acggctattg aacaagaagc ccatttcctc agcagataaa atgcatttgc
     3421 atcaccgctt gttatcttta ggttttaccc ataaaggggc ggtcatgact atttatgcat
     3481 tagcgttagt tttttccttt gtctctttat tgttcagcta ttcaagtaca gtagcatcaa
     3541 ttttattaat tgtcttttgt ttaattggct tagaactatt cattgaacta atcggtctag
     3601 ttggcgaagg acatcaaccg ttgatgtatt tgttacggat tttagggaat cgtgaatatc
     3661 gtcaggagca aatgaaaaag cgacttggca agcattctaa gagaaagtaa agaaacctta
     3721 ggttgctttg cgagagcgta aacctatgat ataattccat taaacttaaa aaagtatatg
     3781 tgtgaaacat atgctttttt tttaagacga tgtttcagta gtaaggagaa atgagcatgc
     3841 aagaaatggt aacaatctcg attgtcactt ataatagtcg ttacattttt aatgtactag
     3901 accaattaaa agccgaactg ggtactgata gtatctatga tattcatatc tatgacaatc
     3961 attctgaaac agcgtatctt gaaaaattaa caacatatga accatttatt actatccatc
     4021 gcgctgaaga aaatcaaggg tttggtcatg gtcataatca agtgttattc aatgcttcga
     4081 caaagtatgc aattattttt aatcccgatg ttttggttac taaagacgtg cttgatcgtc
     4141 tattagaccg tatcaaaata gataagaaca ttgcagtcgt tagccctaaa gtgctaaatg
     4201 aagatggcac gacgcaatat ttagttcgtc aaaaattaga tgttttcgat tatatgttac
     4261 gttttattcc ctttcaattt gtaaagaaaa tttttgataa acgtttgagt atttatgaat
     4321 gtcgcgattt gtcggataca gaaacaacgg atattaaaat gggctcaggc tgttttatgt
     4381 tgattgatcg tgaaaaattc gttgaaattg gtgggttcga tgaacgtttt ttcatgtact
     4441 ttgaagacaa cgatttatgt ttacgctttg gcaaagcagg ctatcggatt ctctatacgc
     4501 cttttgaaac ggttgttcac atgtatgaaa agggcgccca taaaagtgta aattgtttaa
     4561 aatctttatg caatcaatgg ggaaattttt taacaaatgg ggctggaggt tcttttaatg
     4621 agtcaaagat tagcggtagt catcgtctta tatcaaatga aaatggctga tacgccgaat
     4681 tatttgttat taaaagaagt ggtagatcac cccgaattgc acttatttat ttatgacaac
     4741 agcccacttc ctcaagaaga tgcattattt ttacaacaaa atgttactta tcgacataat
     4801 cctgataatc caggactagc gaccgcttat aatgaagcga ttgcttttag tcaagcgaat
     4861 caatgtgaat tattgttgct ccttgaccaa gacacagaag tgccagcctc ttattttgat
     4921 acgttgatca tcatgtcgtt agatccgact gtggcagtct atgttccaat tgtagaagca
     4981 aatggacaac aaatttcgcc agtatatagt gatcaatatg ttggacttaa aggagcaaag
     5041 ccaacagcag ggatagccaa ccaaccgttg atggctatca attctggtac agtcattacg
     5101 gcagaaacac tgcgctggtt ggaaggattt tcggaagaat ttcctttgga ctatttagat
     5161 cattggttct tttatcaatt gaatcaagcc aataaaaaga ttgaagtctt accagtccac
     5221 ctaaaacaag aattgtctgt tttagattat cgtacaatga gttctcaacg ttatcgctct
     5281 attattgaag cagaaacgtt attttatcgt cgatatgatc aagaaaagtt ttcccatcat
     5341 cgacgtcatt tatttttacg cagtagtaag caatttttaa ctgtcaaaaa tcgccaaatt
     5401 tggcggcaaa cattggcaga atttctcaag ttaatgaaag gataatctat gatctcagtt
     5461 tgtattgcga catataatgg agaaaaatat ctcgcggaac aattagatag tattctttta
     5521 caagtcagtg aagaagatga actaattatt tcagatgatg gttctactga tctacgttgg
     5581 aaattttgag aacgtatgca gcgaattatc cccaaattca attgttacaa ggtccagggc
     5641 aaggagtgat tgctaatttt gcatttgcgc ttacgcatac gaaaggcgaa gtaatatttt
     5701 tagcagatca agatgacgtt tggttgccaa ataaagtaac gacagtgaca gaatattttg
     5761 aaacgcaccc tgacatccaa gtggttatta gtgacttgaa aattgttgat gcggatttac
     5821 aagttaccaa tccctcttat tttaagtttc gaaaagtcaa accagggttt tggcgaaatg
     5881 cgataaaaag tggctatatt ggggcaggta tggcctttcg tcaagagatg aaaaacgtca
     5941 ttttacccat tccgccagaa gttcctatgc acgatatgtg gattggctta ttagctgcac
     6001 ggaaaaagca aacgggcctc attaaagaac cattagtgct ttaccgaaga catggagcga
     6061 atgtcagccc tattattacc aaaacaagtt tccaacaaaa attaaattgg cgtgtgaatt
     6121 tattaaaagc tttacatcag cgtttaaagg aacaacgcta aacttttaca gatttgtaaa
     6181 atttacgtaa aaaacatgac aaaccctatg cttaatgcga taatagggaa ggatatttgg
     6241 ttttatagaa actaaaaata gaagtattta aggagattgt tcatgaaagg aattatttta
     6301 gcaggcggaa gcgggacacg cttatatccg ttaacaaaag caacatcaaa acaattaatg
     6361 ccaatttacg acaaaccaat gatttattac ccaatgtcaa cgttaatgtt ggcgggaatt
     6421 aatgaaattt tgattatctc tacaccagaa gatacaccac gttttgaaag cttattcggc
     6481 gatggccatg atttaggcat tcatatcgaa tacgcggtac aagaaagccc agatggtttg
     6541 gcgcaagcat ttattattgg tgaagaattt attggtgatg acagtgtctg cttagtttta
     6601 ggggacaata tttattatgg tggcggctta tcaaaaatgt tgcaacgagc ggcttctaaa
     6661 gaatcagggg caacagtctt tggttaccat gtaaatgatc cagagcgttt cggtgtggta
     6721 gaatttgatg aagagatgcg ggcgctttct attgaagaaa aaccagcaca accgaagtca
     6781 aattacgcag tgacaggttt gtatttttac gacaatgaag tggttgaaat tgcaaaaggg
     6841 atcaaaccgt cagaacgtgg ggaattagaa ataacagacg ttaataaagt ctaccttgaa
     6901 aaaaataaac tttctgttga ggtaatgggc cgtggctttg cttggttaga tacaggcaca
     6961 cacgaatcct tattagaagc gtcaacattt attgaaacaa ttgaaaaacg tcaaaattta
     7021 aaagtcgctt gtttggaaga aattgcttat cgaatgggct atattacaaa agaacaattg
     7081 gtagaattgg cacaaccatt gaagaaaaat ggctacggcc aatacttgct acgtttagca
     7141 gcagaatagg agcgangaaa cgtgaaagtt attgatacaa anttccagga tgtcaaaatt
     7201 atcgaaatgg atgttttcgg tgatcatcgt ggctttttta cagaaagtta ttccaaagct
     7261 aaatttgcag aacatggatt agactttgat tttgtccaag ataatcattc attatcaaca
     7321 gaagcaggtg tcttgcgtgg attgcatttt caaaaaggcg aagctgcgca aacaaaacta
     7381 attcgcgttg taacaggtgc ggtattagat gtgattgttg atattcgtaa agggagtcca
     7441 acctatggcc aatgggaagg ctacatttta tcagaacata atcaccgtca gcttttagta
     7501 ccaaaaggtt ttgctcatgg ttttgtcact ttgacaccga acgtgaactt tatgtacaaa
     7561 tgtgacaatt actacaatgc ggcagcagac ggcggtattg cttttaacga tccagcgtta
     7621 gctattgatt ggccaattgc gccagaaaaa gcgattacgt cagaaaagga tcaaaaacat
     7681 ccaaccttaa aagaatttga agcggaaaat ccgtttatct atggcgaaat ttaagaaaaa
     7741 agtaggagag tttcaattat gaaaaaaatc atcgtaacag gtggagctgg ttttatcggc
     7801 tcaaattttg ttcattatgt tgtaaagaat catccagaag ttcatgtaac tgtattagat
     7861 aaattaacgt atgcaggaaa tgaaaaaaat cttgaaggta ttcccagtga tcgcgtggaa
     7921 ttagtcgtag gagatatcgt tgatgctgaa ttagttaatc gtttagttgc tgaaacagat
     7981 gcggtcgttc actatgctgn tgaatcgcat aacgacaact cattaaacga cccattccca
     8041 tttgtacaaa ccaatctgat tgggacgtac acattgatcg aagcttgccg taaaaacaat
     8101 gttcgttacc accatgtatc gactgatgaa gtttatggtg atttaccttt aagagaagat
     8161 ttaccaggac atggagaagg cgaaggggaa aaattcactg ccgaaacgcc ttacaatcct
     8221 tcaagtcctt attcttcaac aaaagcagga tctgacttgt tagtcaaagc gtgggttcgt
     8281 tctttcaact tacaagcaac aatttcaaat tgttcaaata actatgggcc atatcaacat
     8341 attgaaaaat ttattcctcg tcaaattacc aatgtcttaa gcggtattac accaaaactt
     8401 tatggtgctg gtaaaaatgt tcgtgactgg attcatacaa acgaccattc ttcggctgtt
     8461 tgggcaattt taacaaaagg gcaaattggc gaaacatatt taattggagc cgatggtgaa
     8521 gaagacaata aaacagtgat ggaattaatt ttagaattaa tgggacaacc tgttgatgcc
     8581 tatgagcatg tcaacgatcg tgtaggacat gacttacgtt atgcgattga ctcaaccaga
     8641 ttacgcgaag aattaggttg ggaaccagaa ttcacgaatt tccgtgaagg cttggcagaa
     8701 acaatcaagt ggtatacaga aaatgaagac tggtggcgtg cagataaaga agctgttgaa
     8761 gcaaaatatg cacaaaatgg tcagtaattt tttctgacat gtgagataac agtcgaaagg
     8821 cgatggcaaa gtacaaaagc tactttgccc tgcctttttt tcaagaagga gcgaaaaaaa
     8881 tgattttaat tactggtgga aatggccaat tgggcacaga attacgtcac ctattagacg
     8941 aacaaggaat tgagtatgtt tcaacggatt ccacagaatt agatattact gatgcggata
     9001 gtacgttggc aaaagtgaaa gaaattcaac caagcgtcat ttatcattgt gctgcttata
     9061 cagctgttga taaagcagaa gacgaaggca aggaattaga tgaaaaagtg aatgtagatg
     9121 gcacacgtca tgttgcagaa gctgctaaag cagtgggggc gacacttgtt tacgtaagta
     9181 cagattatat ttttgatgga actaaaaaag aaggcgtcta tgcgattgat gatcaaccga
     9241 atcctttaaa tgagtatggt cggacgaagt tattaggtga acaagcggtc caagaaatcc
     9301 tggacgatta ttatattatt cgaacatcat gggtatttgg tcaatacggt cataactttg
     9361 tctttaccat gcaaaaatta gcggaaacaa gagaccaact aacggtagtg gacgatcagt
     9421 ttggccgccc aacttggaca agaacgttag ccgaatttat ggcatttgtt attgcagaaa
     9481 aagcgccatt tggtgtttat catttgtcta atgaaaacag ctgtagctgg tatcagtttg
     9541 ctaaagaaat tttaaaagat actgaagtgg aagtactgcc agtggattca actcaatttc
     9601 cacaaaaggc gcaaagacca caatattctg tcatggattt aagtaaaaca gaagcgttag
     9661 gctttaaaat tcctacttgg caagaagcct tagcacaaat gttagaaaat gttcaacaat
     9721 aaattgtttt gtgtaagtga ggggttttgt tagagaaaaa gtggaaaggt gtttctcttt
     9781 atgaaggtac ttttaatcat tcctgcttac aatgaggaag aaaacatttt gcggacgatt
     9841 gcttccattg aaacatttaa acaggaagtt acgcattttc aacatgaatt ggattatgtg
     9901 gtaattaatg atggctcgac agatggaacc aaacaaattt tagaagtcaa ccaaattaat
     9961 gccattcatt tagtgttgaa tttaggtatt ggcggggcgg tacagaccgg ctataaatat
    10021 gccttagaaa atgagtatga tgtggcggnt cagtttgatg gtgatggnnn acatgatatc
    10081 natagtttac ctattttact ggaaccatta gcnganggtn aatgtgantt ttcgantggc
    10141 tctcgtttca ttcctggaaa cnaagcgtct ttncaaagtn cnaaaatgcg ccgnttnggt
    10201 atncgtttgt tatccttttg tnntcnaang gcnnctggtn aaacaattta tgangtnact
    10261 nctggttntc gagcgggaaa tcggaaagtg attgcttttt ttgcaaagcg ttatccgaca
    10321 aattatcccg agccagaatc gattgttcac ttaattaaaa aacgctttgt gattgttgaa
    10381 agacctgtca atatgatgga acggcttggt ggtgtttctt cgattcgtgc attggcttct
    10441 gtgaagtata tgctggaagt cggctcagca attctgattg ctccctttat gaaggaggga
    10501 gattaatgct accacccgtg ttagggctag ttttattttt atttgcaatg ggctttttct
    10561 tanacattat tcgaggaatt aataaaatat ttttctccta aaaaatgctt tggattnggt
    10621 tattaatctc aattgtctaa attattttgc tattttcccg catgtggcag aatggttagc
    10681 aatggccttt gggttggaaa caacatcaaa ctttttatta tcagctgcgg tgattgtcct
    10741 tttaatcatg gaaattaaaa attctgtgtt gatttcaaaa cacgaaaatc gcattaaaac
    10801 attattgcaa gaattatcta tcatgaaatc tgaagaaaat aaaaaagatc gctaatgtgt
    10861 agtgaccctt aaaagttgga cctgaaagtc taatatttaa gggtcagctc aatgaatagc
    10921 gatctttttt atttaagatt cataatcaca atgccgacaa taataaccac agcaccaata
    10981 agggcattcg ttgtgattgt ctcttttaga ataagatttg aagcaattaa aatagcgatg
    11041 tttgtacagg caacgcctaa aggaacaatg taagaaacat cggaacgact aataattaac
    11101 atccataaaa taaaactaat taaataacaa aataaaccta ataaagatat aagtgagata
    11161 ttcattgaaa agattgtttg ttggagttgg atgttcaaac tgctagaacc tagtttaaat
    11221 aagaccagac cagcagaaga cagaaatacg taaataataa aaagaaccat aatttccctt
    11281 ctctcaaaaa taatttccgt gcaaaaaaat gcaagacctc cattattgta gcataatctc
    11341 ctaaaaattg gacaagattt tttaatatag cgaaatcagt taaatttttc tttataaaaa
    11401 ggggtctact attgaaaagc taggcgttta tcgataaaat agaaatgttg tttaaaatgg
    11461 catttttgta tccaaaaatt ttagataaaa atagtttatt acggaaggaa taagtatatg
    11521 tttaaagaaa cattttcaat tttcaagaat atttttcaga acaaaaaatt gttattacaa
    11581 ttttcattta atgattttaa ggccaagtat gctggttcag cactaggaat tgtctgggcg
    11641 tttttaacgc cattagtaac tgttttgacg tattggtttg tcttttctgt aggccttcgt
    11701 tctagagctg gcgacaatat gccattcatt gtctatttag taacagggat ggtaccttgg
    11761 ttcttctttt cagattcgtt attatcagcc acgaatgtgt ttcgtgaata tagttattta
    11821 gttaaaaaag tcgtgtttaa tgtacaaatt ttaccaacgt ctaaaatttt atcgaacttg
    11881 tacacccact tgtttttcat tcnaattggn tttgtaatta ctacagctaa cggttantac
    11941 ccaagtctgt acagtttgca attaatttac tacttagctt gtttattagt ctttttaaca
    12001 gcaattacgt ggattactgc ttcaacacaa ccatttttac ctgatattat gcaatttatc
    12061 aatatcatta tgcaaacagt tatgtggaca ttgccaattt tatggcaacc aactggaatg
    12121 attgcgacaa tcttaaaaat caatccatta tattatattg ttcaaggata ccgcgaatct
    12181 tatttaggcg gtgcatggtt ctgggaacat tggcaatata gcttatattt ctggggagtt
    12241 actattgttt tactattaat tggctcaacc gtgtttagac gcttaaaacc acatttttca
    12301 gatgtactat aaggagagaa cgacatgtca gaatatgcaa tcgatatcca acatattacc
    12361 aaaacataca acatgtataa aaagccgtcc gatcggttta aagaagcgct tagtccaacc
    12421 aaaaaatctt accacgattt gttttatgcg ttagacgatg tcacgatgca aattaaaaaa
    12481 ggcgagatga ttggctttgt cggcgaaaat ggttctggaa aatcaaccat gttaaaaatt
    12541 attacaggag tattaacgcc aacctccggg tccatggtga ttaatgggaa aatttcagcg
    12601 ttgcttgaat taggttcagg ttttaaccct gaatattcag gatatgaaaa tattttctta
    12661 aatggaatgg tcttgggttt ttcccgagaa gagatggaag agcgtgtcca agatgtcatt
    12721 gattttgctg acatcggcga tcatttgtat caaccagtta agacatactc tagtggtatg
    12781 tttgtccgct tggcttttgc ggtagccatt aacgtggatc ccgatatttt aattgtcgat
    12841 gaagcgttgg ctgtcgggga tttagagttt caattaaaat gtatggaaaa atttacagaa
    12901 attaaaaatt ctggtaaaac aattttattt gtttctcacg atgtaaactc catccgtcgt
    12961 ttttgtgaca gaactttttg ggttgcaaca cgggaaagtc cttgaatatg gagatacgat
    13021 ggacgtgacg accaactacg aaaacttttt ggaaaagaaa tcaattaaaa cgggtgaccg
    13081 cgaagcgacc atgaaagatg aaaccccaac accagatatt attgaagtgg atcatgcgga
    13141 acttttaaat gcggattatg aaccattaga aatggtaacg caagatgaaa aagtgattgt
    13201 aaaaattgaa tatactgtca aaaacgacca aattaagaag cctgtttgtg gggtcgctat
    13261 tcgaacagtg gacaatcatt atgtctgtgg cttaaatacg ttgttagatg gcgtgcaaat
    13321 tccttggaaa aaaggacgga atgtttttta tttagaatat gaaaaaatgt cattattaac
    13381 aggtgaatat tattttgata ttgctttctt tgaggaacat gcaacagtcc cattagtcta
    13441 caaaacaaaa tacgtgacga tgtttattac cggtcgttat gccggagaag gaattgtcat
    13501 cttagatcat aaatggaagg atacgacaaa agatgaagta tgattttgaa atggaaacag
    13561 acgagagtac cagtgttggg aaaatcgtag cacaaatcaa agaaaatagt gatgtcttgg
    13621 aatttggtcc aggtaatggg cgaatgacta gctatttgat ggaagaaaaa aagtgccagg
    13681 tctcaattgt tgaattagac aaagaacttt atgatcatgt cagtcaattt tcaacagatg
    13741 ccttttatgg caatattgat gaaaatgatt gggtcgaata ctttgctggt aagacgtttg
    13801 attatatcgt ttttgcagat gtgttggaac atttaatgaa tcctcaaagc gccttagcaa
    13861 aagtcaaacc gttttttaaa ccaggcggtc aaatcttaat cactttccct aatttggcgc
    13921 ataattctgt cttaattgat ttatttaata atcgtttaac gtggaatgaa actgggctgt
    13981 tggatgctac gcataaatca ttctatttac aagaaggatt tgaaaaagtt tttgtagaag
    14041 ttggtttata cattgccaaa gaagatttta catttaatca agttggctac aacgaaattc
    14101 ctacgacgta tgaagcgtta cctgtagaag tacaagcagc ttttaaagcg cgtccctttg
    14161 gcgaagtgta tcagtacttt tttgccttga ctgctgaacc agtagaacag ccagagcgag
    14221 tgacaccagt aaattcatac aatgaaaaaa acgttcatat tttaattaat tgcggcgaag
    14281 aaaaagagac tgagttggat caaccagttg atttacaaaa acctgaaaca aaacagttcc
    14341 aactgaagat accagaagac gtccaactga taaaattatt cccaagttta acgggggcaa
    14401 ttattaaatt atccatgacg atagacggcg agacagtccc agtcgcagcc acgaatgctt
    14461 ttctggtaca agagaatatc tattatttct tagatacgca agtacctgta atcgaagtaa
    14521 ccgatgcaca aatggcaggc aaagacctga cagtagacat tgattatttc tttgaaggca
    14581 actattcaga acgtgaaaat acctttattc atgcactgtt agatgaaaga aatcaatttt
    14641 tggaagaaat gaataaacag acggagattg cccatatgca tactggaaaa tataaacgga
    14701 atcacgtnan ctaaatttga naaaatgatt aatttaacca tcggatgata ttgctcgcga
    14761 ttgtagaaaa taacgtttct tgttatccgg agggttgggc ttatgacaac caaacaaatt
    14821 atcccggtta agattcagca ttgcagaagc ttagtgaatc agtcacttat acggtggaaa
    14881 cagaatcccg tcgtgatgtt attgatatgt ttgaatttgg aaggcgatca ggtttatggt
    14941 tttgtcatta cgatttaaag atccagagga tttaccagcc tacacgttaa acattgacac
    15001 aaaatcaggc cagaaggttc aatacgtggt ggagcgtcca aacatggttc aaccaggcac
    15061 aaaatttgat cgagcatggc gttcgattca gacacgtggt ttgatgggct cagtgaagtg
    15121 gtactttaaa cgacaagaaa aagcagaagc ccctgttgac gtggaggcag ttttagcgga
    15181 aattaaaacg ttccaatttc agcctaaaat ttctgtcgct gtgcctgttt ataatgtcga
    15241 agaaaaatgg cttgcagcgt gcgtttcttc tttacaaaat cagtactatg aaaattggga
    15301 gttatgttta gcagatgatg catcgccaag cgaacatatt aagcccatgc tagaaaaata
    15361 taaagaacta gatcaacgaa tcaaagttat ttatcgcgaa gaaaacggac atatttcaga
    15421 agcaactaac tcagctttgt cgattgctac tggcgatttt gttggtttca tggataacga
    15481 tgatgaatta gcgccacaag cattatatga agtggtcaaa gctttaaaca cagacccaac
    15541 gattgatttt ctttatactg atgaagataa aattacagaa aatggtcgtc gcttcaacgc
    15601 gttttacaaa tcggactgga atccagaact gattttaaac cataattaca ttacacactt
    15661 tgttgttgtg aaacgtgatt tattagaaaa agtaggcgga ctgaactcag catataacgg
    15721 cgctcaagac tatgatttcg tattacgagc aacggaacaa gcaacgaaaa tcaagcatat
    15781 tcctggtatg atgtatcatt ggcgtgccat tgaatcatcg actgctctaa accctgaaag
    15841 caaaggttac gcctatgtag ctggtcaaaa agcggtccaa gcggcaacgg aacgccgtgg
    15901 cttaaaagca caagtagaga ttgccgaatt ttatggttcc tataaaatta actatcttta
    15961 tgatcatgtg ccgatggtat cattgattat tacgaatgat acagagaata tgagtagtta
    16021 cttacgtcaa ttattagaaa aaactgccta tacaaattat gaaattctat tgcctgcacg
    16081 cttcgagaat caaataaata tccaaaatga ccgtcttcgt tatgtttcaa cagaaactcg
    16141 tcatggcatg attcaagctg ctaagggaga atatgtggct ttattaaatg ctggattggt
    16201 accaacgaaa aatgattggt taaaagagtt aatgaacatt ggtcaacaag agacctctgg
    16261 tttagtgact ggccgcgtag ttgacgcacg cgatcgcgtg gaaacggtgg gagtatcagt
    16321 tgatacagac aaaggtcgat tactttatcc cgaaaaaggc acccctggta aaagcttagg
    16381 ttactattac agaattgctt taccaagaaa tattcaagca gcaactgaag actgcttact
    16441 attcaacaaa caactttacc taaatttaga aggaattaac gaaagcttag gaaaagaatg
    16501 gatgggtgtc gatttatcgt tacaatttgc tagcgcttgg taaacgaaat gtatatgtgt
    16561 cctatgcaat tttgaaagca gacgaaaaaa tgcaaaacca tgataaaaaa ggatcttata
    16621 aagaacttgc ggaaaaatgg accgcggaag ctttagttga tccctaccga aatccgaaac
    16681 atctataagg agaatgcaca tgaatgaaga cattaaggtg atctttgata gtatctatcg
    16741 cgacaaaaca acaaataatt taaccattac aggttgggcg ttggatacaa tcactaaaga
    16801 aagcccaact ttcacaatta ataatgaaaa ccaagtgtcc gcttataaca ttcagcgcgt
    16861 tttacgtgaa gatgttaatc aaatttatca aacagagcct gcgattgaag ctggctttgt
    16921 tgttacactt gaaggaatta aacaaaaaaa agtactccct tttcattttc aatcatcagc
    16981 acatgttgta acggtggatt ttcccttgaa taaaaaatat ccagtgattc cagggacaga
    17041 agataaagta actcgtcttt ggataaaagc caaaaaagga tttaagtata tggctaaaaa
    17101 tggtatttct cataccattc aacgagcgaa aattgagaaa ctgagaaatc aagcttcgta
    17161 tcctaactgg ttagctagaa atgaagtact agacatagaa gcgatgacgc aagaaatcgc
    17221 aacatttcat tatcagccta aaatttccat tgcgatgcca gtgtataatg ttgaagaaaa
    17281 atggcttcgg ttgtgcattg attctatttt gaatcaagtc tatactaact gggaattatg
    17341 tatggccgat gatgcctcaa cagatcctaa tgtcaaaaag attttaacag agtaccagca
    17401 attggatgag cgaattcggg tcgtctttcg tgaacaaaat ggtcatattt ccgaagcaac
    17461 caactctgct ttagcgattg ctaccggaga atttgtcgcc ttactagaca acgatgatga
    17521 attagcgatc aatgcttttt atgaagtggt taaagtgctg aatgaaaacc cagaactgga
    17581 tttaatttat agtgatgaag ataagattga catggatgga aatcgttctg atccagcctt
    17641 taaaccagat tggtcacctg atttactttt aggaaccaat tacatttcgc atttaggcgt
    17701 gtatcgtcgg agtattctag aagaaattgg cggctttcga aaaggttacg aaggttctca
    17761 agactacgat ttagtcttaa gatttactga aaaaacgaca aaagaacgca tcacacatat
    17821 tccaaaagtt ctttactatt ggcggatgct gccaacctca acagcagtgg atcagggctc
    17881 caaaggttat gcttttgaag cggggctaag agccgtgcaa gatgcgctcg ttcgtcgagg
    17941 tattaatggt catgcaacgc atggggcggc gaatggctta tacgatgttt attatgacat
    18001 tgaatctgaa aagttagtct caattattat tccaactaaa aatggctata aagacgtaca
    18061 acgttgtgtt tcatcgatta ttgaaaaaac aacctaccaa aattacgaga ttattatggc
    18121 tgataatgga agtacagatc caaaaatgca cgaattatat gcagaatttg aacaacaatt
    18181 acctggccgc tttttcgttg aatcaatcga tattccattc aatttctcaa ctattaacaa
    18241 tcgtgcagcg aaaaaagcgc acggagagta tttattattt ttaaataatg ataccgaagt
    18301 gattacagag aattggttaa ccttgatggt ttcatttgct cagcaagaac ggattggctg
    18361 tgtaggtgcg aaattattgt atccaaataa tacggtccaa cacgcaggcg ttattttagg
    18421 attaggtggt gttgctggac atggtcatta tggttatccc catggtgact taggctattt
    18481 tggtcggtta gctattaatg ttaattattc agcagtaact gccgcatgct tacttatgaa
    18541 aaaagcagat tttgatgcag ttggtggttt tgaagaagcg tttaccgtag ctttcaatga
    18601 tgttgattta tgcttgaaag tccaagcttt aggacgtgac aatgtctggc ttcatgaagc
    18661 agagctttat cattttgaat ctcaaactcg tggatatgat gataaaggca aaaagaaaaa
    18721 acgttttgaa caagaaaaag tgatgatgga agaaaaatgg ggacctttaa ttgaaaatga
    18781 tccattttat aatcctaatc tgacaaggga tattccc
//
