Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000794.1:
Cluster 1Saccharide119983

BGC0000794, S-layer glycan biosynthetic gene cluster from Geobacillus stearothermophilus. Locus 1. Partial MIBiG entry.

Chemical compounds

Compound: S-layer glycan

Class-specific details

Biosynthetic class(es):

Gene cluster description

S-layer glycan (BGC0000794). Gene Cluster 1. Biosynthetic class = Saccharide. GenBank AF328862. Click on genes for more information.


biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

Literature references

1. Schaffer C et al. (2002) The surface layer (S-layer) glycoprotein of Geobacillus stearothermophilus NRS 2004/3a. Analysis of its glycosylation. J Biol Chem 277(8):6230-9. doi: 10.1074/jbc.M108873200. Epub 2001
2. Novotny R et al. (2004 TI) Genetic organization of chromosomal S-layer glycan biosynthesis loci of Bacillaceae. Glycoconj J 20(7-8):435-47. doi: 10.1023/B:GLYC.0000038290.74944.65.
3. Novotny R et al. (2004) S-layer glycan-specific loci on the chromosome of Geobacillus stearothermophilus NRS 2004/3a and dTDP-L-rhamnose biosynthesis potential of G. stearothermophilus strains. Microbiology 150(Pt 4):953-65. doi: 10.1099/mic.0.26672-0.
4. Zayni S et al. (2007) The dTDP-4-dehydro-6-deoxyglucose reductase encoding fcd gene is part of the surface layer glycoprotein glycosylation gene cluster of Geobacillus tepidamans GS5-97T. Glycobiology 17(4):433-43. doi: 10.1093/glycob/cwl084. Epub 2007 Jan 3.
5. Steiner K et al. (2007) Functional characterization of the initiation enzyme of S-layer glycoprotein glycan biosynthesis in Geobacillus stearothermophilus NRS 2004/3a. J Bacteriol 189(7):2590-8. doi: 10.1128/JB.01592-06. Epub 2007 Jan 19.
6. Steiner K et al. (2008) Molecular basis of S-layer glycoprotein glycan biosynthesis in Geobacillus stearothermophilus. J Biol Chem 283(30):21120-33. doi: 10.1074/jbc.M801833200. Epub 2008
7. Messner P et al. (2008) S-layer nanoglycobiology of bacteria. Carbohydr Res 343(12):1934-51. doi: 10.1016/j.carres.2007.12.025.