LOCUS       BGC0000795             30344 bp    DNA     linear   BCT 08-JUL-2008
DEFINITION  Aneurinibacillus thermoaerophilus strain L420-91T S-layer glycan
            biosynthesis gene cluster, complete sequence.
ACCESSION   BGC0000795
VERSION     BGC0000795
KEYWORDS    .
SOURCE      Aneurinibacillus thermoaerophilus
  ORGANISM  Aneurinibacillus thermoaerophilus
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Aneurinibacillus group; Aneurinibacillus.
COMMENT     On Mar 13, 2004 this sequence version replaced AY205257.2.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 14:13:09
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 30344
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..30344
                     /db_xref="taxon:143495"
                     /mol_type="genomic DNA"
                     /note="type strain of Aneurinibacillus thermoaerophilus"
                     /organism="Aneurinibacillus thermoaerophilus"
                     /strain="L420-91T"
                     /type_material="type strain of Aneurinibacillus
                     thermoaerophilus"
     misc_feature    1..30344
                     /note="S-layer glycan biosynthesis gene cluster"
     subregion       1..30344
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="saccharide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..30344
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     regulatory      2247..2253
                     /regulatory_class="ribosome_binding_site"
     gene            2266..4917
                     /gene="wscA"
     CDS             2266..4917
                     /codon_start=1
                     /gene="wscA"
                     /product="putative S-layer associated protein"
                     /protein_id="AAS55709.1"
                     /transl_table=11
                     /translation="MKRITRTIVPFTLAGLLSVNGLLPAVADAASNAASGQFKDVSANH
                     WASQYILKMGLRDVVAGYNDGTFRPDESVTQLQALAMVVRNMGLTEEAKKYESTAIPYS
                     VPDWAKGSVALAISKGLIKPTEKNFYPDMPASRAWVAQLMVRMIDKESEVGKASSTLFT
                     DGSSIPDWAKGYVDVAVANDLISGYKEGAGTAFKPNRAVTRAEMVTMLSKGERFLKIES
                     ANTRIGYLQSVSGNTLTLTDESGKEQYRYTITSDTQFYNGNVKTTSANLGTDSQLLVIS
                     ENGQARYVEVINFKQKSKYDKAVLEKVFIEANTVVLRLADGKLQTYTIAKDAVIGAGMD
                     RLKLSDFVNGDEVEFRLNTDGQVSELFRTGLSKAQSLQGSVYDVDKQNKLLTIKASSGK
                     LETYQYSDITYVEYKGKRFPSIEDLLPGDEVKLELTNGIVSKVVVEAEAGKTNGGDVGT
                     VKAISDKDRFVTLQGEDGKIQAYTVAQNAIITLNGALAPTLADVKVGDKVEFKVQKDMI
                     TSLAVKNRTVYNNKDLLSGSIFALDKKNRILSLKTTNGELKAYEVVSNAEILINGSSKK
                     ELDALDKDMNVSIQLNEDNKIIYINADNRVRAEVVRVNTDDKLLTVKLATGETKVYVVD
                     PKVDITIYDVRGEDLRDLRIGDKIAMKMNGNKITDIEVERSFVYRVTENGGTYSNRLTV
                     QDENGRSHDVIIDSRVTFSIPGIPYPRVSDVKKGDVLRATYLGDDLKEIAIVPNVYGQV
                     VSVSPEMGRIVVRDLNGVTSEVTAAYGTTIQIGDRQYTNINVLKPGDRVQVAEATNGAK
                     SIVVLTKVETTFNSLDPLGDRIYTAKQSYYLPDSLFNRQVNLQSLLRGLRKGDNVAIYL
                     LNNEVYEIEKVN"
     stem_loop       4918..4960
                     /function="putative termination signal"
     regulatory      5085..5092
                     /gene="wscC"
                     /regulatory_class="ribosome_binding_site"
     gene            5085..5674
                     /gene="wscC"
     CDS             5108..5674
                     /codon_start=1
                     /gene="wscC"
                     /product="putative transcriptional regulator"
                     /protein_id="AAS55710.1"
                     /transl_table=11
                     /translation="MFAGCSGVKKLLDYLITSKTRIKLLLKFFLNAEARGYLRSLAEEF
                     GESTNAVRVELNRLTEAGLLEAESEGRTKVYRANRGHALFEDLHNIVKKYIGIDQLIEE
                     VLRKLGNVELALITGDYAKGIDSGIIDLVIVGGVDKGYLQVLVEKAEELIRRKIRILIL
                     NRQGFEKLKGKFEEENALVVWNQLK"
     regulatory      5728..5734
                     /gene="gmd"
                     /regulatory_class="ribosome_binding_site"
     gene            5728..6713
                     /gene="gmd"
     CDS             5742..6713
                     /EC_number="4.2.1.47"
                     /codon_start=1
                     /function="converts GDP-D-mannose to
                     GDP-6-deoxy-D-lyxo-4-hexulose; reduces
                     GDP-6-deoxy-D-lyxo-4-hexulose to GDP-D-rhamnose"
                     /gene="gmd"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     255.4; E-value: 1.4e-77)"
                     /gene_kind="biosynthetic-additional"
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="AAS55711.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.2e-14, bitscore:
                     44.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKALITGITGQDGSYLAELLLEKGYEVYGLIRRTSTPIMVNIEH
                     LKDKITLVSGDLTDLSSLVAIIKKIQPDEVYNLGAQSFVATSWEQSILTGQVTALGVTN
                     ILEALRMEKPDAKFYQASSSEMFGKVVEMPQKETTPFYPRSPYGVAKVYGHWITVNYRE
                     SFDMFACSGILFNHESPRRGIEFVTRKITDGVARIKHGLQKELRLGNLDAQRDWGFAKD
                     YVECMWLMLQQEKADDYVIATGEMHSVREFCEIAFGHVGLNYEDYVVVDPKFFRAAEVD
                     VLLGDASKAINKLGWNPRKTSFEQLVTMMVDNDMDLIRKQLK"
     regulatory      6719..6725
                     /gene="rmd"
                     /regulatory_class="ribosome_binding_site"
     gene            6719..7663
                     /gene="rmd"
     CDS             6734..7663
                     /codon_start=1
                     /function="reduces GDP-6-deoxy-D-lyxo-4-hexulose to
                     GDP-D-rhamnose"
                     /gene="rmd"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     234.4; E-value: 3.4e-71)"
                     /gene_kind="biosynthetic-additional"
                     /product="GDP-6-deoxy-D-lyxo-4-hexulose reductase"
                     /protein_id="AAS55712.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.3e-17, bitscore:
                     52.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5.1e-11,
                     bitscore: 32.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRALITGVAGFVGKYLANHLTEQNVEVFGTSRNNEAKLPNVEMIS
                     LDIMDSQRVKKVISDIKPDYIFHLAAKSSVKDSWLNKKGTFSTNVFGTLHVLDAVRDSN
                     LDCRILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKASVGMLARQYVKAYGMDII
                     HTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLEAVRDFTDVRDIVQAYW
                     LLSQYGKTGDVYNVCSGIGTRIQDVLDLLLAMANVKIDTELNPLQLRPSEVPTLIGSNK
                     RLKDSTGWKPRIPLEKSLFEILQSYRQA"
     regulatory      7664..7669
                     /gene="wzm"
                     /regulatory_class="ribosome_binding_site"
     gene            7664..8464
                     /gene="wzm"
     CDS             7679..8464
                     /codon_start=1
                     /gene="wzm"
                     /product="ABC-transporter protein"
                     /protein_id="AAS55713.1"
                     /transl_table=11
                     /translation="MLKAIWRYRGFIWGLAARDFQSRYLNSILGSLWAILNPLAIIVVY
                     TIIFSQVMRAKLPEIDNSLAYSIYMCAGLLPWNYFIETLQRFQNVFLEQGNLLKKVSFP
                     RTSLPIYVVISSTINFSIIFGLFIVFLLITGQFPGWYFLGVFPLLLLQQMFAVGIGMFL
                     GTINVFFRDIGHAFGVFLQFWFWLTPIVYPIKAVPEKFKSIFELNIMYPIVKSFQTIFV
                     YQKWPQWNELFIPFLGALIMMLLGYVTFKKLEKEMVDEI"
     regulatory      8452..8459
                     /gene="wzt"
                     /regulatory_class="ribosome_binding_site"
     gene            8452..9690
                     /gene="wzt"
     CDS             8464..9690
                     /codon_start=1
                     /gene="wzt"
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 142.7; E-value:
                     2.4e-43)"
                     /gene_kind="transport"
                     /product="ATP-binding protein"
                     /protein_id="AAS55714.1"
                     /transl_table=11
                     /translation="MSRIEVKNLGKKYKKYARKWHRLFEWITGRKKHEEKFVLKGLSFN
                     VLEGESVGIIGHNGAGKSTLLKILTGTTQPSEGEFKVNGRVAALLELGMGFHPDFTGIQ
                     NVYMSGQLMGLSNEEITRLLPEIERFAEIGDYIHQPLRTYSSGMAVRLAFSVATAIRPD
                     VLIVDEALSVGDAYFQHKCFDRIKKFRSEGTTILFVSHDPGAVKNLCDRAILLDQGIMI
                     KEGTPEEVLDYYNAIIAKREADYNIKQSIGKDGKVDTRSGNGDIKIEKVELFSGNRKVN
                     AVQVGEEIEIKIDLKCMKKIDCPTVGFMFKDRLGNEVFGTNTYYLKKNIESLQIGEKFS
                     VIFKIPANFGIGNYSLTVAAHEGHTHTAKNYEWWDHAALLQVVPGDEAPFVGVCYLKAT
                     VEFSKGVMV"
     regulatory      9676..9682
                     /regulatory_class="ribosome_binding_site"
     gene            9676..11093
                     /gene="wscD"
     CDS             9690..11093
                     /codon_start=1
                     /gene="wscD"
                     /product="putative methyltransferase"
                     /protein_id="AAS55715.1"
                     /transl_table=11
                     /translation="MKIEFDDAEIDVKDIMRQIKENVLARGDVREIPEKVVVNGQNYLT
                     ELEIEQHLLQKTWDYSLDYPIKSNRKVIGRLIVFCKRLIRKLIHWYVNPGVKKQINFNA
                     NVVRTLNPLIEQVKQITDYNESLEQKLEQKLEQKLEQKLEQKLEQKLEQKLEQKLEQKL
                     EQKLEQKLEQKLEQKLKQRLKLFDEEQKNTIQPIYHTIRVQTERLRRIERMLKNKESKV
                     LTSNENIDVVSLEEKIKETDTEFDYYLFEEYYRGSREEIINRQKKYLKYFSEGQYVLDL
                     GCGRGEFTELLLSKGIKVTCVDIDEDMVAYCKDRGFPIVKSDLFSYLNSVPDRSVDGIF
                     LGQVIEHLTTEQFISLVNISYRKLKPMGYFIAETPNPRSLSIFAQSFYMDPTHVKPVHP
                     YTSKFVLESAGFFDVEIHYFSPNHESTQLPYLELEGVKSNSLDKFNQVLQVWNEIIFGN
                     QDYYVVGRK"
     regulatory      11082..11087
                     /gene="wscE"
                     /regulatory_class="ribosome_binding_site"
     gene            11082..12162
                     /gene="wscE"
     CDS             11101..12162
                     /codon_start=1
                     /gene="wscE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 105.8;
                     E-value: 4.9e-32)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative glycosyltransferase"
                     /protein_id="AAS55716.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.1e-29,
                     bitscore: 93.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIINQLLPSISPGDAVSNSVLNIMNLLNEMGFDSKIYAESIHPAM
                     QEVALPISSCPKDCSLIYHMAIGYPFAYKLPNFKGKKILIYHNITPDVFFRDYKEIQEL
                     CIEGRRQLKFLVPYIDYAWADSEYNRLELEELGYKNTHVTPIIINFEDYKRNPSQKLME
                     KFKAEKHITNILFVGRIAPNKKQEDIIKVFYYYKKYINEDSRLFLVGSYSGMERYYNEL
                     MELVKELQLEDVYITGHISFEEILAYYTNADLFLCMSEHEGFCVPLVEAMHFEIPIIAY
                     KSSAIGETLGNGGILVLEKQYKEIAELMHIVLSTPKIKERMIINQKKRLEFFSKKNTEN
                     IFRERIQEVLLGS"
     regulatory      12167..12172
                     /gene="wscF"
                     /regulatory_class="ribosome_binding_site"
     gene            12167..13360
                     /gene="wscF"
     CDS             12179..13360
                     /codon_start=1
                     /gene="wscF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 68.8;
                     E-value: 8.2e-21)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative hexosyltransferase"
                     /protein_id="AAS55717.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.4e-17,
                     bitscore: 54.5, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRRIAFVVQRYGLEVNGGSEASCRMIAERLSKYYEVEVLTTKAI
                     DYTTWADYYEHDIEEINGVFVRRFSTNQIRNMDRFGSITYEILNNDKRTVYEELEWMRQ
                     QGPVSFEMIEYIKKYSNQYDVFIFFTYLYFTTFHGIQLVPEKSIFVPTAHDEPYIYFSI
                     FRPIFHLPRYNIFLTVEEQEFVHKLFRNSYLPFDVAGVGVDVPQKILSQQQFKEQFKIV
                     DPYVIYVGRIDESKGCKELFDYFMRYKEETRNDLKLVLMGKSVIHIPKCEDIIPLGFVS
                     EEEKFSGIAGAKFLIMPSKYESLSMVVLESLSLNRPVLVNEECEVLKGHCERGNAGLYY
                     KSYEEFKTCVNLLLQHEHLCNKLGKNGKGYVDKYYRWSTIIDKFIRAIESIVV"
     CDS             13523..13834
                     /codon_start=1
                     /note="OrfTn"
                     /product="putative transposase"
                     /protein_id="AAS55718.1"
                     /transl_table=11
                     /translation="MTRRKYSIDFKKQVVKEAKETGNLAAVARRYELSANMVGHWKREF
                     ESGKHGEIDFSMVPVLDAEEVVKENEQLKRLLGEQALELAILRDLIKKKNPHLLKNLK"
     regulatory      14636..14641
                     /gene="wscG"
                     /regulatory_class="ribosome_binding_site"
     gene            14636..16850
                     /gene="wscG"
     CDS             14649..16850
                     /codon_start=1
                     /gene="wscG"
                     /product="putative integral membrane protein"
                     /protein_id="AAS55719.1"
                     /transl_table=11
                     /translation="MGNRFFQIINLKSFFAYIIITLLSFLMLVYIMELWDVDLNVPLVY
                     LGDGLSAGMLVKSVIDNGWFLENQYLGAPIGANLYDYPLSDGFHFLLMKLIALFHPDYA
                     FVMNFYLILTFPFTAIVSFFVFRQFNISYIPAFVGSMLYTFLPYHFFRWAGGHIFLAAY
                     YTVPLVVMVFLWMFCEKNFLFFYNEDKGKYKFELFSFKSMVSIIACLLISSSGIYYAFF
                     TCFFLAVQGLAISIFRKRFIPIVVAGFLISTVCIGVLANVVPNIIYTHYNGENSEVGKR
                     SPLEADLYGLKISQLLLPISGHRISFLKELKEKYNSSFPLVNENDNASLGILGSTGFLI
                     SLYIFLFRREQKNDIKQNLSFLNVCSILFASIGGLSTLFSILISPQIRGYNRISVFIAF
                     FSIFILVLVFNDFKKKFISNRALKIVFNTFLIIICLVGILDQTNKNFFLPYEILEKEYK
                     NDKEFIRKIEVSLPKGAMIFQMPYVSFPEQPPVNQMGGYDLAKGYLHSTNLKWNFGATT
                     GRESDAWQKNTINKTLDEMIETLSLAGFKGIYIDRNGYADKGIEIEGKLSSILKTKPLI
                     SENQRLSFFNMETYNKEVENKYTKNELNLKRDNALHLVLLTWKNGFYGLEQNESGSWRW
                     SQDKSSMIINNYSSKERIVTIEMSFQTGYEQLSSLFIETPTFKEELKVNNKEKKYIKTI
                     RIPSGSYIIKFTSNAEKVNVPDESRNLFFRVNNFKIDYK"
     regulatory      16873..16878
                     /gene="fdtA"
                     /regulatory_class="ribosome_binding_site"
     gene            16873..17304
                     /gene="fdtA"
     CDS             16885..17304
                     /codon_start=1
                     /function="converts TDP-6-deoxy-D-xylo-hex-4-ulose into
                     dTDP-6-deoxy-D-xylo-hex-3-ulose"
                     /gene="fdtA"
                     /product="dTDP-6-deoxy-3,4-keto-hexulose isomerase"
                     /protein_id="AAS55720.1"
                     /transl_table=11
                     /translation="MENKVINFKKIIDSRGSLVAIEENKNIPFSIKRVYYIFDTKGEEP
                     RGFHAHKKLEQVLVCLNGSCRVILDDGNIIQEITLDSPAVGLYVGPAVWHEMHDFSSDC
                     VMMVLASDYYDETDYIRQYDNFKKYIAKINLEKEG"
     regulatory      17358..17363
                     /gene="fdtC"
                     /regulatory_class="ribosome_binding_site"
     gene            17358..17945
                     /gene="fdtC"
     CDS             17367..17945
                     /codon_start=1
                     /function="transfers an acetyl group from acetyl-CoA to
                     dTDP-D-Fucp3N"
                     /gene="fdtC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 66.3;
                     E-value: 4.6e-20)"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-D-Fucp3N acetylase"
                     /protein_id="AAS55721.1"
                     /transl_table=11
                     /translation="MSSSSETCFVHPNAIVETKKIGNNTRIWAFVHILPQAMIGDNCNI
                     CDHCFIENDVFIGNNVTVKSGIYIWDGVYIEDNVFLGPNVVFTNDVFPRSKVYPESFGR
                     TIVKKGASIGANSVIVAGNIIGEYAMVGAGSVVTRDIPDYALAYGNPARIKGYVCQCTS
                     KLKFIDNQAVCQCGKRYKYADGIVSQLII"
     regulatory      17952..17957
                     /gene="fdtB"
                     /regulatory_class="ribosome_binding_site"
     gene            17952..19055
                     /gene="fdtB"
     CDS             17964..19055
                     /NRPS_PKS="Domain: Aminotran_1_2 (38-303). E-value: 2e-07.
                     Score: 22.3. Matches aSDomain:
                     nrpspksdomains_fdtB_Aminotran_1_2.1"
                     /codon_start=1
                     /function="transfers an amino group from L-glutamate to
                     dTDP-6-deoxy-D-xylo-hex-3-ulose"
                     /gene="fdtB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     380.6; E-value: 1.4e-115)"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-6-deoxy-D-xylo-hex-3-ulose aminase"
                     /protein_id="AAS55722.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.8e-134,
                     bitscore: 438.5, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.5e-08, bitscore:
                     22.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIPFLDLRQINMRYQKEIQQAMNRVLESGWYILGGEVDDFERKFA
                     SYCGAKYCIGVANGLDALTLIIRAYDIGLGDEVIVPSNTYIASILAISANGATPVLVEP
                     DINTYNIDPLKIEEKITSRTKAIMVVHLYGQSCDMESINLIAKKYNLKVIEDCAQAHGA
                     IYNGKRVGSLGDAAGFSFYPGKNLGALGDGGAITTNDAELAERLNVLRNYGSHKKYENL
                     FKGVNSRLDELQAAILSIKLSYLDDDNQRRREIAAYYLEHIKNPFIHLPTVTDDKAHVW
                     HLFVVRVKEREAFQYYLAEQNIQTLIHYPIPPHKQKAYSEWQQESFPISEQIHSEVVSL
                     PISPVMSREEVERVVEAVNRYGY"
     aSDomain        18078..18872
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_fdtB_Aminotran_1_2.1"
                     /evalue="2.00E-07"
                     /label="fdtB_Aminotran_1_2.1"
                     /locus_tag="fdtB"
                     /protein_end="303"
                     /protein_start="38"
                     /score="22.3"
                     /tool="antismash"
                     /translation="DFERKFASYCGAKYCIGVANGLDALTLIIRAYDIGLGDEVIVPSN
                     TYIASILAISANGATPVLVEPDINTYNIDPLKIEEKITSRTKAIMVVHLYGQSCDMESI
                     NLIAKKYNLKVIEDCAQAHGAIYNGKRVGSLGDAAGFSFYPGKNLGALGDGGAITTNDA
                     ELAERLNVLRNYGSHKKYENLFKGVNSRLDELQAAILSIKLSYLDDDNQRRREIAAYYL
                     EHIKNPFIHLPTVTDDKAHVWHLFVVRVKEREAFQYYLAEQNI"
     regulatory      19028..19033
                     /regulatory_class="ribosome_binding_site"
     gene            19028..19977
                     /gene="wscH"
     CDS             19045..19977
                     /codon_start=1
                     /gene="wscH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123:polyprenol-monophosphomannose synthase ppm1
                     (Score: 141.7; E-value: 5.8e-43)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative glycosyltransferase"
                     /protein_id="AAS55723.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1e-26, bitscore:
                     84.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTRKKFSILVPIYFNELNIPYTVPRLQNLQNILPEYDLEFVFVD
                     DGSQDNSLSLLLEAKKSDERIKVIKLSRNFGSMSAISAGLHYVTGDCVGIIAADLQDPP
                     ELFAEMIKSWESGKKIVMATRSDREESFSQKLFSNSYYFLMDKFAIKNYPKGGFDFVLL
                     DKQVVQELNNINEKNTNIMSLIFWLGHEQDFIPYVRQKRELGKSRWTMSKKIKLFIDSF
                     VSFSYVPIRFMSLVGFFTALLSFLYGIFAVFNTLTGNITVPGWTSVIGLITFLLGLIMV
                     MLGIIGEYLWRVLDEARNRPHYIIDEVYE"
     regulatory      19960..19966
                     /gene="wscI"
                     /regulatory_class="ribosome_binding_site"
     gene            19960..20329
                     /gene="wscI"
     CDS             19970..20329
                     /codon_start=1
                     /gene="wscI"
                     /product="putative integral membrane GtrA-like protein"
                     /protein_id="AAS55724.1"
                     /transl_table=11
                     /translation="MNKEFFRFLIVGGLNTGITYGIYLVLLLGFPYVLAYSGSYIIGVF
                     ISYYLNSKIVFQTNFSIKKMLQFPLVYVVQYVINTMFLYFLVQMNISEKLAPILVVILS
                     IPITFILSKYILKKS"
     regulatory      20345..20350
                     /gene="rmlA"
                     /regulatory_class="ribosome_binding_site"
     gene            20345..21277
                     /gene="rmlA"
     CDS             20360..21277
                     /EC_number="2.7.7.24"
                     /codon_start=1
                     /gene="rmlA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 290.9; E-value:
                     1.6e-88)"
                     /gene_kind="biosynthetic-additional"
                     /product="glucose-1-phosphate thymidyltransferase"
                     /protein_id="AAS55725.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.5e-12, bitscore:
                     38.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIILAGGSGTRLYPLTRAISKQLLPVYDKPMIYYPLSVLMLAG
                     IRDILVISTPEDTPRFEQLLGDGSELGISLSYAIQPSPDGLAEAFIIGEDFIGQDNVAL
                     ILGDNIFYGQGFTPLLQRAVNRKKGATIFANVVKDPERFGVVEFDENNKVLSIEEKPVY
                     PKSNFAVTGLYFYDNDVVKIAKQIEPSARGELEITDVNKIYLERGDLNVELLGRGFAWL
                     DTGTHESLLEASQFIQTIEKRQGLKVACLEEIAYYKGYINKEQLIRLAEPLKKNEYGAY
                     LLELAEKGSLQTGSINTKEAVLYG"
     regulatory      21255..21260
                     /gene="rmlB"
                     /regulatory_class="ribosome_binding_site"
     gene            21255..22301
                     /gene="rmlB"
     CDS             21270..22301
                     /EC_number="4.2.1.46"
                     /NRPS_PKS="Domain: NAD_binding_4 (11-201). E-value:
                     2.8e-15. Score: 47.9. Matches aSDomain:
                     nrpspksdomains_rmlB_NAD_binding_4.1"
                     /codon_start=1
                     /gene="rmlB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     265.8; E-value: 9.2e-81)"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="AAS55726.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 7.4e-16, bitscore:
                     48.7, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 9.8e-14,
                     bitscore: 41.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.2e-15, bitscore:
                     47.9, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKEEKINSILVTGGAGFIGSNFIPYFLEKYNNYRIINLDALTYA
                     GSLNNLQEVEHHPRYKFVKGDINNRQLLEYLFEQFNIKGVIHFAAESHVDNSIKGPDIF
                     IETNVKGTFTLLETARKFWMIAPFKYREGYEQCRFHHISTDEVYGTLGEEGYFTEETPY
                     APNSPYSSSKASSDMIVRSYFHTYGLNVVTTNCSNNYGPKQHDEKLIPTVIRKALANEH
                     IPIYGDGKNVRDWLYVLDHCQAIDAVYHRGVCGEVYNIGSRNEQNNLQIAHMICELLDR
                     MKPIAKGRSYKELITLVQDRPGHDRRYAIDPKKIETQLGWKAEENFEDGIRKTVQWYLN
                     KYE"
     aSDomain        21303..21872
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rmlB_NAD_binding_4.1"
                     /evalue="2.80E-15"
                     /label="rmlB_NAD_binding_4.1"
                     /locus_tag="rmlB"
                     /protein_end="201"
                     /protein_start="11"
                     /score="47.9"
                     /tool="antismash"
                     /translation="VTGGAGFIGSNFIPYFLEKYNNYRIINLDALTYAGSLNNLQEVEH
                     HPRYKFVKGDINNRQLLEYLFEQFNIKGVIHFAAESHVDNSIKGPDIFIETNVKGTFTL
                     LETARKFWMIAPFKYREGYEQCRFHHISTDEVYGTLGEEGYFTEETPYAPNSPYSSSKA
                     SSDMIVRSYFHTYGLNVVTTNCSNNYG"
     CDS             complement(22500..22898)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238:transposase
                     (Score: 126.8; E-value: 1.8e-38)"
                     /gene_kind="other"
                     /note="OrfTn"
                     /product="putative transposase"
                     /protein_id="AAS55727.1"
                     /transl_table=11
                     /translation="MDEEIAHLLFQDECMIRDYQAVQYTWFLRGKQRIIPTYGKHHGVK
                     LIGVLNYETGRVHCVEEEQYDAEAFLRFLQHVPKQYPTGKIVMVLDNARIHHARLIQPF
                     LEENQNRLELVFLPPYSPEMNLIEGLWK"
     CDS             complement(22891..23409)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1238:transposase
                     (Score: 62.2; E-value: 8.8e-19)"
                     /gene_kind="other"
                     /note="OrfTn"
                     /product="putative transposase"
                     /protein_id="AAS55728.1"
                     /transl_table=11
                     /translation="MNIHPTELQTVQQAMKQTKDKRMYERYQAISLFLQGYKYEQISAI
                     IGRNKKTVGTYVKAYREQGLEGLVRHASPGAPHKLTPEQEQELVDIIVNHLPVDVGFEA
                     RYNWTLALIVALVEQKWQKTYTLRGMSRLLGSLGLSYTKPTYTLAQADPEKQRGFREET
                     FPALKKTDG"
     regulatory      23514..23520
                     /gene="manC"
                     /regulatory_class="ribosome_binding_site"
     gene            23514..24922
                     /gene="manC"
     CDS             23528..24922
                     /EC_number="2.7.7.13"
                     /codon_start=1
                     /gene="manC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MannoseP_isomer"
                     /gene_kind="biosynthetic-additional"
                     /product="mannose-1-phosphate guanylyltransferase"
                     /protein_id="AAS55729.1"
                     /sec_met_domain="MannoseP_isomer (E-value: 6.2e-25,
                     bitscore: 78.5, seeds: 17, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLILLSGGSGKRLWPLSNDSRSKQFLKVLKNDNNEFESMVQRVW
                     NQLHTVGLAEDSYVATSKSQVDMLHAQLGTEVPLIIEPERRDTFPAIALAATYLYSMEG
                     VREDDVISVLPVDPYVESRFFDRVKDLETALVQSSAELALIGVKPTFPSEKYGYIVPKK
                     GEHDVVANVLAVDYFVEKPSTSRAQELMKQQAFWNCGIFAFKLGYLISLLKEKKLPTDY
                     EEMLHTYNQLPKISFDYEVVEKAQNIIMLPYEGEWKDLGTWNTLTEEMNTNLLGKGIIS
                     EGCENTHLINELDIPVTILGISNAVIAASPDGILVTDKEASPRIKDIMKNFNQRPMYEE
                     RRWGWYRVLDHTKVENGNEVLTKRIGVHAGKNLSYQIHHKRSEVWTIISGEGQFVLNDQ
                     LYHVKPGDVLQIPVGAKHAIRAITDLQFVEVQTGSELIEEDIIRLCMTWEETLDCCKDC
                     IVKVIR"
     regulatory      24931..24936
                     /gene="wscJ"
                     /regulatory_class="ribosome_binding_site"
     gene            24931..26108
                     /gene="wscJ"
     CDS             24939..26108
                     /codon_start=1
                     /gene="wscJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 186.3;
                     E-value: 1.7e-56)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative mannosyltransferase"
                     /protein_id="AAS55730.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 4e-40, bitscore:
                     127.9, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDNLQGPVFLGGIIIKVLFESQPLLGRRTGIGRYVERLTASLQE
                     NQDIDLFYWFNQQFNVKLLQMLDVPSTKIRNSRYFYKVIRRLMKPNFLHDLPVDLGESF
                     DIFHGGSCITYQTTKAKNALTIHDLAFLQFPEVASEQTDRHHSLWLPYSIKKADHIIAV
                     SQHTKEDIIRYYDVPDEKISVIYLAADDQIKKEDRPLKEEVQAKYNLPEKYALYVGTIE
                     PRKNIPFMLEGYALAKQKYKFPHKLVIAGAKGWKYEKVYETFEKYRLHNDVIFTGYVED
                     MDLPVLYENADVFLFPSRYEGFGIPVLEAMQCGVAVIASNVSSLPEIVGEAGRLVSLEK
                     PEEFIDSIGELLTNEAKRREYEEAGRRQARMFSWKKAASETVTVYRSLL"
     regulatory      26125..26130
                     /gene="wscK"
                     /regulatory_class="ribosome_binding_site"
     gene            26125..27270
                     /gene="wscK"
     CDS             26137..27270
                     /codon_start=1
                     /gene="wscK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 191.8;
                     E-value: 3.7e-58)"
                     /gene_kind="biosynthetic-additional"
                     /product="putative glycosyltransferase"
                     /protein_id="AAS55731.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 5.5e-45,
                     bitscore: 143.7, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILQVNKFYPPVIGGVEKVVYDLVEGMCSLAEMEVLVANTEWKY
                     VQEIEHKAKIHRVPSIGTYFSMPVAPTFPLWLKKIKTDIIHFHFPFPLGKLSYLLVDKI
                     ANIPAKTVVTWHSDIVRQKRFLKLYHPFLKRFLEKVDTIIATSPNMVEASPYLKEHKDK
                     CRVIPLGIDVKEWEKTDKLFENVKKVREEVAIKPIILFVGRLVYYKGVEYLIEAMTEIN
                     ASLFLVGEWPLKPLLQKRAEELGITEKINFLGGASKEQLVTYLHACDIFVLPSVERSEA
                     FGIVQLEAMACGKPIVSTNLATGVPFVNQDGKTGIVVPPKDIKSLTQALTFLIENESVR
                     KQYGERGKERVYEHFTREKMVQSVYTLYQELLEGGTT"
     gene            27270..27605
                     /gene="wscL"
     CDS             27270..27605
                     /codon_start=1
                     /gene="wscL"
                     /product="putative mannosyltransferase"
                     /protein_id="AAS55732.1"
                     /transl_table=11
                     /translation="MGDIYVNARFMNQVVTGVQRYAWEITNHLRDRVHIIQPGKSFSGE
                     AGHFWEQIVLPGRMPRNALLWSPAGAGPLLVSKQVVTLHDIAHLEHLTILVVLQCFSSR
                     QVSWLRV"
ORIGIN
        1 gagctcatcg gttgggtcgg ccagaagaaa aaaccgcttt ggaaacggcg cgcagaatca
       61 agcagatgac aacaggaaag caatgagtga aagagacgag tgcttggcgc tcgtcttttt
      121 attaggcttt tttccaccag ctttttaccg cccaccgcaa cggcatgctg cttgacgtct
      181 ggttggacgc ttttggcgtt ttctatagta ttctcctcgc gttatggctg cttcgctccc
      241 gccgctcaaa aacgttcgct tgcaaatcat aaaggaaata aaacgatttt cttctaaaaa
      301 agacctataa taaagtagaa taataattag atcgactatt aataattggg agaggaaaaa
      361 gatgaataaa aagaacaccg ttgattccgt tggtcacggt gtgtgggtta ctatctggtg
      421 catggttgcc cggagcgccg gttgttttgg cacaggaaat caaaacagga gcgccggctg
      481 ttgtcagcat ccagaccgaa aacggaatgg acgcgaaagc caaacagccg actgacgtaa
      541 gatgggtgat tcgttttaat acgccaatcg aacgctatac ggtcgatgat agcgctttgt
      601 tcgtaaagga tgaatccggt aataaagtat ctgtcacgct tgtgtttggc gataaagatc
      661 aaaccattac ggtcaaaccg cccacaaacg gatatggatc gggacaaaca tactttttgt
      721 gcgtaaacga tagtatttac gccaagtcag gcaagaaact cagcgcctcg gtcacacaga
      781 aattccaaat tcaaaatgaa attgtaagca ttcagggaga taaagaccac accttcttca
      841 tcggtaaaaa agaagtttgg agaagcggaa aggaaaactt cctaccgaca acagaacaag
      901 gcaaaaacct tgcgaccccg cagcttttta aagagctgag cgatataaaa accattgtga
      961 atggcaagga gcatttcctg gcgctgacca acgacggaac ggtctgggcc tggggcacaa
     1021 acaaatcggc gaactgggcc atggtacgaa ccagtcacgc aatacgccgg tacaggtaaa
     1081 aggattgagc gatgttatag aagtcgtagc ggccaacgac agtgatggca atggctatag
     1141 tctggcatta acgaaggatg gcaccattta tgcgtggggc agcaataaat acggccagct
     1201 gggattgggc gaaggagcag gagcctttgt taaaacgccc acgagagttt tggaggtgcg
     1261 ggacatagcg tccattgctg gcggtcaggg ccacgcgttt gccgtaaaaa atgatggcac
     1321 ggtttatgcg tggggccgta acaatgaagg tcagcttggc gacgacacga ccaaagaccg
     1381 ctacatccct gtccgcattg atgatttgaa aggaatttcc aggatcgtca tgggaacgaa
     1441 ccatatcatc gcttttcaac ggagtggcaa tatgtatgcg tggggcaata acgatttcgg
     1501 ccagcttggt aatggtagta atggtgctag taaaactcct gtccaggtta actttttatc
     1561 cgatgtccag cagctcttta cggttggaga cagcaatttt gctttgaaga gtgatggaac
     1621 ggtttgggcc tggggcaaga acgatgaagg acaattgggt gatggaacga gagaaaatcg
     1681 tttgatgcct gtaaaaatcg aagtcctcac taaaatcaag atgatttctg taagtgaaga
     1741 tcacgggctt gcgcttgatg aagacggaaa agtctgggcc tggggcaaaa ataatcaagg
     1801 gcaattaggc ataggaaaaa cagaaggaaa ggaaagcagc gtgcctgttc aggttggcaa
     1861 actatcaaat atcaaacaag tatatgcgaa gtccggcagc agtttcgcca ttggagagga
     1921 cggaacggtc tgggcctggg gcgaaaacgg agcagggcaa ctaggggaag gaaccgccaa
     1981 gaaccagccg gctcccgcaa aaacccctac attttagcag tgcgaaacag tccggctgct
     2041 ccatcagccg gactgttttc tgatgatatc gcttgaaaaa ctcgcaacgt agcgttctgc
     2101 ctttgctata taaacatgag ggtaagcggg caaagaccgc gggctttctt gaaacattta
     2161 caatattatc ttcgtctagt atacgttacc tgcaaaatct tttaaaatta agtatagtag
     2221 agaatgacat gatacaaaaa caagaaagag gagtgaccgt gagacatgaa gcgtattaca
     2281 cgtactatcg ttccgtttac gcttgccgga ctgcttagcg taaacggact tctacctgct
     2341 gtggctgatg ccgcgtcgaa tgctgcatcc ggccagttta aagatgtgtc tgccaatcac
     2401 tgggccagcc agtatatttt gaagatgggg cttcgcgatg tggtggccgg atataacgac
     2461 ggaacgttta gaccggacga aagtgtaacg caattgcagg cgctggcgat ggttgtccga
     2521 aatatgggac ttacggaaga agcgaaaaaa tacgagagta cggcgattcc gtacagtgtg
     2581 ccggactggg caaaaggttc cgttgcgctg gcgatttcca aaggtctgat taagccaacg
     2641 gagaaaaact tttatccaga tatgcctgct tcgcgcgcct gggtcgcaca gcttatggtt
     2701 cgcatgattg acaaggagtc ggaagtaggc aaagcatctt ccaccttgtt taccgacgga
     2761 tcaagcattc cggattgggc gaaggggtat gtagatgtag ctgttgcgaa tgacttaatc
     2821 tccggataca aagaaggagc aggaacggct ttcaagccga accgtgccgt aacgcgcgcg
     2881 gaaatggtca ccatgctcag caagggagaa cgtttcctta agattgaatc ggctaacacc
     2941 cgcatcggtt atctgcaaag cgtaagcggc aatacgttaa cgctgaccga tgagtcaggc
     3001 aaggaacagt accgctatac cattacaagc gacacccagt tttataacgg aaatgtaaag
     3061 acaacatccg ctaatctggg aacggacagt caattgctcg ttattagtga aaatggacag
     3121 gctcgatacg tggaagtcat caactttaaa caaaagtcga aatatgacaa agcggtactg
     3181 gaaaaagtgt ttatagaagc caacacggtt gtattgcgcc tggctgatgg aaaattgcaa
     3241 acttatacga tcgccaagga tgcggtaatc ggagcaggaa tggacaggct taagctttcc
     3301 gattttgtga acggcgatga ggtagaattc agattgaaca cggatggaca ggtttctgaa
     3361 ttgttccgta cgggcttaag caaggcacaa agcttgcaag gcagtgtcta tgatgtcgac
     3421 aagcaaaaca aattgctgac gattaaagcg tccagcggaa aactggagac gtaccagtac
     3481 agtgatatta cgtatgtcga atacaaaggc aagcggttcc cgagcatcga agatttactt
     3541 ccgggcgatg aggttaagct ggagctgacg aacggcatcg tcagcaaggt tgttgtcgaa
     3601 gcggaagccg gcaaaacaaa tgggggagac gttggaacgg ttaaggcgat cagcgataag
     3661 gatcgattcg taactctgca aggtgaagat ggaaagattc aggcatatac ggttgcacag
     3721 aacgccatta ttacgctaaa cggtgcgctt gcgcctacgc tggcggacgt gaaagtcggc
     3781 gacaaagtgg aatttaaagt acagaaggat atgattacgt cactggctgt gaagaatcgt
     3841 accgtctaca acaataaaga cttattgtcc ggcagcatct ttgctctgga taaaaagaac
     3901 cgtattcttt cgctgaagac caccaacggt gaactcaagg cgtacgaggt cgtttccaac
     3961 gcggagattt tgattaacgg ttcatcgaaa aaagagctgg atgcactgga taaggatatg
     4021 aacgtttcga ttcagctgaa cgaagacaac aaaattatct atattaacgc cgataaccgc
     4081 gtccgggccg aagtggtacg cgtaaatacg gatgataagt tgttgacagt gaagctggca
     4141 acaggcgaaa cgaaagtata cgtagttgat ccgaaggtag atattacgat ttacgatgtg
     4201 cgcggtgagg atctgcgcga tctgcggatt ggcgacaaga tcgcgatgaa gatgaatgga
     4261 aacaagatta cggatattga agtggaacgc tcgttcgttt accgtgttac agaaaatggg
     4321 ggcacatact cgaatcgcct caccgtacag gatgaaaatg gaagatcgca tgatgtcatc
     4381 atcgatagcc gcgtgacctt ctccattccg ggtatcccgt accccagagt gtctgatgtg
     4441 aagaagggcg atgtgctacg ggccacatat ttgggtgatg atctcaaaga aattgcgatt
     4501 gtgccgaacg tatatggaca agttgtatct gtgtctccgg aaatgggccg gattgtggtg
     4561 cgtgacttaa acggcgtgac cagcgaagtg actgccgcat atggaacaac gattcagatt
     4621 ggcgaccgcc aatatacgaa tatcaacgtt ttgaaaccgg gtgatcgtgt acaggtggca
     4681 gaggcaacca atggcgcgaa aagtatcgtt gtactgacga aagtcgagac tacctttaat
     4741 tcgcttgatc cgctgggcga ccgaatctat accgcgaagc aaagctacta cctgccggac
     4801 agcctgttta accgtcaggt caacctgcaa tcgctgttgc gcggtctgcg taaaggtgac
     4861 aacgtagcga tttacctgct gaataatgaa gtgtacgaaa tagagaaggt aaattaaatg
     4921 aagaaagact cgcggctttc atccgcgagt cttttctatg attcgatgtg aaatgcgcgt
     4981 ttattcaggg catacagttc aaataaacaa agcgaaaaaa ttttttgacc gcaacaaacc
     5041 gctgcggttg acgtctaata aaatgacgag taaaattatt actcggaaat gatttacttt
     5101 cctgctgatt tttgcaggat gttccggagt gaagaaattg ctggactatt taattacgtc
     5161 gaaaacgcgg atcaaacttt tgctgaagtt ttttttgaac gcagaagcgc gcggctattt
     5221 gcgttcgctg gcggaagagt tcggcgagtc gaccaacgcg gtgcgcgtgg aactgaaccg
     5281 gctgacagaa gcgggcttgc tggaggcaga aagcgaaggc cggacgaaag tgtaccgcgc
     5341 caaccgtggt cacgcgctat ttgaggactt acataatatt gtaaagaaat acataggcat
     5401 tgatcagtta attgaagagg tattgcgtaa acttggaaat gtggagcttg cacttattac
     5461 tggtgattac gcaaaaggga ttgactccgg gattattgat ttggtgattg taggcggagt
     5521 tgataagggg tatttacagg tgttagtaga gaaagcggaa gagttaattc gtaggaagat
     5581 tcggatattg atattaaata ggcaagggtt tgaaaagtta aaagggaagt ttgaagaaga
     5641 gaatgcgtta gtagtgtgga atcaattaaa ataaacaatt tataaatatg gatagttttt
     5701 attttgaaag attatgtaga tttttttgga ggagcaaaat tatgaaaaaa gctttaatta
     5761 caggaattac aggacaagat ggctcttatt tagcagaact actattagaa aaaggatatg
     5821 aagtgtacgg tttaattcgt cgcactagta ctcctattat ggttaatatc gagcatttaa
     5881 aagataaaat cacactagtt tccggtgatc tgacagattt atcttcgcta gtggcaatta
     5941 taaaaaagat tcaaccggat gaagtatata acttaggagc gcaatctttt gtagcaacat
     6001 catgggaaca gtctatttta actggtcaag taacggcgct gggagttaca aatattttag
     6061 aggcattgcg aatggaaaaa ccagatgcta agttttatca agcatcttct agtgaaatgt
     6121 ttggaaaagt tgttgaaatg ccacaaaaag aaacgactcc attttatccg cgtagcccat
     6181 atggtgtagc aaaagtatac ggacactgga ttactgtgaa ttaccgcgag agttttgata
     6241 tgttcgcatg ttcagggatt ttatttaatc acgaatctcc gagacgtggt atagaattcg
     6301 ttacacgtaa aattacagac ggggtagcga gaattaaaca cggtttacaa aaagaacttc
     6361 gtcttgggaa cttggatgca cagcgtgatt ggggctttgc aaaagactat gttgaatgta
     6421 tgtggttgat gttacagcaa gaaaaagcag atgattatgt gattgcgaca ggagaaatgc
     6481 attccgttcg tgaattctgt gagattgctt ttggacatgt agggctgaat tatgaggatt
     6541 acgtagttgt tgatccaaaa ttcttccggg ctgccgaggt agatgtattg ttgggagatg
     6601 ctagtaaagc aattaacaaa ctaggatgga atccacgtaa aacatctttt gaacaattag
     6661 taacaatgat ggtggataat gatatggatt taatccgtaa acagttaaaa taaataatga
     6721 aggtgtatta ataatgagag ccctaatcac tggagttgca ggcttcgtag gcaaatattt
     6781 agctaaccat ctaactgagc aaaatgtaga agtttttggg acatctagaa ataatgaagc
     6841 aaaattacct aacgttgaaa tgatatcatt agatattatg gattctcaaa gggttaaaaa
     6901 ggtaatctct gatattaagc cagactatat ttttcatctt gcagccaaga gttctgttaa
     6961 ggactcttgg cttaataaaa aggggacatt ttctacaaat gtatttggta ctttgcatgt
     7021 attggatgca gttcgcgaca gtaatctaga ttgtcgtata ctgaccatag gatcttctga
     7081 agagtatgga atgatattac cagaagaatc acctgtatcg gaagagaacc aattacgtcc
     7141 tatgagtcct tatggtgtaa gtaaagcttc tgttgggatg cttgctagac aatatgtcaa
     7201 agcatatggg atggatatta ttcatacgag aacatttaat catattggcc cgggtcaaag
     7261 tttaggtttt gttacgcagg attttgctaa acagattgtt gatattgaga tggaaaagca
     7321 ggaaccaatt ataaaagttg gaaatctaga ggctgttcgt gattttaccg atgtacgcga
     7381 tattgtgcaa gcatattggt tattatctca atatggaaaa acaggtgacg tatataatgt
     7441 atgttctgga attggcacaa ggattcaaga tgttcttgac ttattactag ctatggctaa
     7501 tgtgaaaatt gatactgagt taaatccgtt acaattaaga ccttctgagg ttccaactct
     7561 tataggttct aataaaagat tgaaggattc tacagggtgg aaaccaagaa ttcctcttga
     7621 aaagtcttta ttcgagattt tacaaagtta ccgtcaagca taagagaggt gctaaattat
     7681 tttaaaggca atttggagat acagaggatt tatttggggg ttagcagctc gcgattttca
     7741 atctaggtat cttaattcaa tactgggttc actgtgggct attcttaatc ctttagcaat
     7801 cattgtagta tatacaatca ttttttctca agtaatgaga gctaaactcc ctgagattga
     7861 taactcattg gcgtatagta tttatatgtg tgcaggacta ctgccatgga attattttat
     7921 tgaaacatta caacgttttc aaaatgtatt tttagaacag gggaacttat tgaagaaagt
     7981 gagctttccg cgaacttcat tacctattta tgtggtgata tcttcgacga ttaactttag
     8041 tattattttt ggtttgttta ttgtgttttt gttaataaca ggccagttcc caggttggta
     8101 ttttcttggt gtttttcctc ttttgttatt gcagcaaatg tttgctgtag gaatagggat
     8161 gttccttgga acaataaatg tattctttag agatataggg catgcgtttg gcgtgttttt
     8221 gcaattctgg ttctggttaa cgcctattgt ctatcctatc aaagctgttc ctgagaaatt
     8281 taaatctatt tttgaattaa atattatgta tccaatagtt aagtcatttc aaactatttt
     8341 tgtttatcaa aaatggccac aatggaatga gctattcatt ccgtttttag gtgctttaat
     8401 tatgatgtta ttagggtatg tgacttttaa aaagctggaa aaagaaatgg tggacgagat
     8461 ttaatgtcta gaattgaggt taagaaccta gggaaaaagt ataaaaaata tgctagaaaa
     8521 tggcatagac tgtttgagtg gataactggt cgtaaaaaac atgaggaaaa atttgtttta
     8581 aaggggttat cttttaatgt tttagaaggg gaatccgttg gcattatagg acataatggt
     8641 gctgggaaaa gtacattgtt aaagatttta acaggtacaa cacagccttc ggaaggagaa
     8701 tttaaagtta atggaagggt ggcagcttta cttgagttag gcatgggctt tcatcctgat
     8761 tttacaggca tacaaaatgt atatatgtct ggacaattaa tgggtttatc aaatgaagag
     8821 attacaagat tgcttcctga aattgaaaga tttgctgaaa ttggagatta tattcatcag
     8881 ccgttgagaa catattcaag cggtatggct gttcgtttag ctttttcggt agcgaccgct
     8941 ataagaccag atgttttaat tgttgatgag gctttatctg taggagatgc ctattttcaa
     9001 cataaatgct ttgatagaat aaaaaagttt cgtagtgagg gaacgacaat tttatttgtt
     9061 tcacatgatc ctggtgccgt caaaaatctt tgcgatcgag caattctttt agatcagggg
     9121 ataatgatta aagaagggac acctgaagag gtactggatt attataatgc aattattgcc
     9181 aagcgtgaag cagattataa tattaagcag agcataggta aagatggaaa agtagatact
     9241 agatctggta acggtgatat taaaattgaa aaagttgagt tgttttctgg caatcgtaag
     9301 gtgaatgctg tccaagtagg ggaagaaata gagataaaaa ttgatttgaa atgtatgaaa
     9361 aaaattgatt gtccaactgt tggatttatg tttaaagata ggttagggaa cgaagtgttc
     9421 gggacgaata cttactactt aaaaaagaat atagaaagtt tacaaatcgg tgaaaaattt
     9481 tctgttatat ttaaaattcc tgctaatttt ggtataggaa attatagttt aactgtagca
     9541 gcacacgagg ggcatacaca tacagcgaag aactacgaat ggtgggatca tgctgcttta
     9601 ttacaggttg ttccgggtga cgaggctccg tttgtaggtg tgtgttattt aaaagctaca
     9661 gtagagttta gtaaaggagt aatggtttaa tgaaaatcga atttgatgat gctgaaattg
     9721 atgtaaaaga cataatgaga caaattaaag agaacgtttt ggcaagagga gatgtacgag
     9781 aaatcccgga aaaagtagta gttaacggtc aaaattatct aaccgagtta gaaatagagc
     9841 aacatttatt acaaaaaacc tgggattatt cattagatta tcctatcaaa tcgaaccgta
     9901 aagttattgg tcggttaatc gtattttgta agaggttaat tcgtaagcta attcactggt
     9961 atgtgaatcc gggtgtaaaa aagcaaataa atttcaatgc aaatgttgtt cgtactctta
    10021 atcctcttat tgaacaagtt aagcaaataa cagattataa tgaaagtcta gaacaaaagc
    10081 tagaacaaaa gttagaacaa aagctagaac aaaagttaga acaaaagcta gaacaaaagc
    10141 tagaacaaaa gctagaacaa aagttagaac aaaagctaga acaaaagtta gaacaaaagc
    10201 tagaacaaaa gttagaacaa aagctgaaac agagactaaa actttttgat gaagaacaga
    10261 aaaacactat acaacctatt tatcatacaa taagagtaca aacagagaga ttgcgtcgga
    10321 ttgagagaat gttgaaaaat aaagaaagta aagttttaac ttcaaatgag aatatagacg
    10381 tagtttcttt agaagaaaaa attaaggaaa cggacacaga atttgactac tatttatttg
    10441 aagaatatta cagaggttct cgagaagaga ttataaatag acaaaagaag tatctaaagt
    10501 atttttctga gggacagtat gttttagacc ttggatgtgg gcgtggagaa ttcacagaac
    10561 ttttgctttc taagggaata aaagttactt gtgtagatat agatgaagac atggtagcat
    10621 attgcaagga tcgtggtttt ccgatagtta aaagtgattt gttttcctat ttaaattctg
    10681 ttcctgatcg ttcggtagat ggtattttct taggacaagt tattgaacat ttaacaaccg
    10741 aacaatttat ctcacttgta aatatctctt ataggaagtt aaaaccaatg ggctacttta
    10801 ttgcggagac accaaatcca cgtagtctat caatttttgc acagagcttt tatatggatc
    10861 ctacccatgt aaagccagtt catccatata cctcaaagtt tgttttagaa tcagcaggtt
    10921 tctttgatgt tgagatacat tatttttctc caaatcatga aagtacacaa cttccatact
    10981 tggaattaga gggtgttaag tcaaattcac tagataaatt taatcaggtt ttgcaagtct
    11041 ggaatgagat aatttttggt aatcaagatt attatgttgt aggaaggaag taaatattca
    11101 ttgataatta atcaactatt accttctatc agtcccggag atgcggttag taatagcgtc
    11161 ttaaatataa tgaatttgtt aaatgaaatg ggttttgatt ccaagattta tgccgaatca
    11221 attcatcctg caatgcaaga ggttgctttg cctataagta gttgcccaaa ggattgttct
    11281 ttgatttatc atatggcgat tggttatcca tttgcatata aactgcctaa ttttaaggga
    11341 aaaaaaattc ttatttatca taatatcact cctgatgttt tttttagaga ttataaagaa
    11401 attcaggagc tttgtataga aggtagaaga caattaaagt ttttagtacc atatattgat
    11461 tatgcttggg ctgattctga atataatcga ttagagttag aggaattggg ctataaaaat
    11521 acacatgtaa caccaattat tataaacttc gaagattata aaagaaatcc aagtcaaaag
    11581 ctgatggaaa aattcaaagc agaaaagcat ataactaata ttttatttgt tggtcgtata
    11641 gcccctaata aaaaacaaga agatattatc aaagtgtttt attattataa aaaatatatt
    11701 aatgaagatt ctcgcttgtt tttggtaggt tcttatagtg ggatggagag gtactataat
    11761 gagcttatgg agcttgttaa agagttgcag ttagaagatg tgtatataac aggacatatt
    11821 tcgtttgaag agatattggc ttattataca aacgcggatc tttttttatg tatgagtgag
    11881 catgaagggt tttgcgtgcc gttagttgaa gcgatgcatt ttgaaattcc tattatagcc
    11941 tacaagagta gtgcaatagg tgaaacatta gggaatggcg ggattcttgt attagaaaag
    12001 caatataaag agattgcaga gttaatgcat atcgtattaa gcacacctaa gattaaagaa
    12061 agaatgatta taaatcaaaa gaaacgttta gagttttttt ctaaaaagaa tacagaaaat
    12121 atatttagag aacgcataca agaggtgctt cttggaagtt aatagtggag gagttgctat
    12181 gaagcgacgg attgcttttg tagtacagag gtatggattg gaagttaatg gtggttcgga
    12241 agctagttgt aggatgattg cagaacgctt atctaaatat tatgaggtag aagtattaac
    12301 tacaaaagct attgattata caacttgggc tgattattac gagcatgata tagaagaaat
    12361 aaatggtgtt tttgttcgaa ggttttctac taatcaaata aggaatatgg ataggtttgg
    12421 ttccataact tatgaaatac taaataacga taagagaact gtatatgaag agttagagtg
    12481 gatgagacag caaggaccag tttcttttga aatgatagag tatataaaaa aatatagtaa
    12541 tcaatatgat gtttttatat tttttacata tttatacttt actacatttc atggtataca
    12601 attagttcca gaaaagagta tttttgtgcc gacagcgcat gacgagccat atatatattt
    12661 ttctattttt cgacctatat tccacttacc acgctacaat atatttctta cagttgagga
    12721 acaagaattt gttcataagc tttttcgtaa ttcatacctt ccattcgatg ttgccggagt
    12781 aggtgtggat gttccacaaa aaattctttc tcagcaacaa tttaaagaac aatttaaaat
    12841 tgtagatcct tatgttattt atgttgggag gattgatgaa tcaaaaggtt gtaaagaact
    12901 ctttgattat tttatgcgtt acaaagaaga aacaagaaat gatttaaagc ttgtgttaat
    12961 gggaaaatcg gttatacata ttccgaaatg tgaagacatt atacccttag gatttgtttc
    13021 ggaggaggag aaatttagtg gaattgctgg agctaagttt ttaatcatgc cttcaaagta
    13081 cgaaagttta tctatggttg ttttggagag cctatcttta aataggccag ttctagttaa
    13141 tgaagaatgc gaagttttaa aagggcattg tgaacgtggg aatgctggct tatattacaa
    13201 gagttatgaa gagtttaaaa catgtgtaaa tctattgctt caacacgagc atttatgtaa
    13261 taaattaggg aaaaatggga aagggtatgt agataagtat tatagatggt caaccattat
    13321 agataaattt atacgagcaa ttgagagtat agtcgtttag aagcgcatgt cttttatttt
    13381 ttctgtgaaa aactttgatt ttcatgttga ggcttgtggc tgataggtct tgaaggtttt
    13441 ctgccttttt agccccctag agaagttgga cactaagggt gtattttgat tacacttata
    13501 gtgacagagg gggaagacat caatgacaag aagaaagtat tcgattgatt tcaaaaaaca
    13561 agtggtgaaa gaagcgaaag agaccggtaa tttagcagcc gttgcccgcc gttatgagtt
    13621 atctgctaac atggtggggc actggaagcg agagttcgag agcggaaaac atggagaaat
    13681 tgatttctct atggttccgg tccttgatgc cgaagaagtt gtgaaagaaa acgaacaact
    13741 taaacggtta cttggcgaac aagcattaga acttgcgatt ttacgtgatt tgataaaaaa
    13801 gaaaaaccct cacttgctga aaaacttgaa gtagcggaac gctatattca gcagggctat
    13861 ccaaaacggc tagtcttgcg ttttgcccgg attccacgct ccacgtatta ctaccatcga
    13921 aaacgaaaag ggcagaacgt ggaaccagtg aaaagtgagg gacgagccat accgggctat
    13981 tccctagagc aggacggctc ggtcattgcg tatcataatt ggtctgtcct gtgaggcaaa
    14041 ggatgcgagt cgtacggtac aacaggcatt gtttaaacgg caattatttg gagaaacacg
    14101 tcccgttctt cgttccgata atggcccaca gtttacgtct catcatttta tacaagcatg
    14161 tgaaacgttt ggaattgttc atgagcgtat tccgccacga acaccgaata tgaatgggca
    14221 catcgaagcg tttcatcgca tcctggaaga tgaatgtctg gcacgttagt ttatgtccta
    14281 tacagaggcg tatcaagttg taacagatat ccgcttttat aacgagagac gaatccattc
    14341 gagcatttgc gatttagctc cacaagagtt ttatgcgctc caaatagaac gtaagttcgt
    14401 aattagagaa gtgcgagtat aagcgaggaa ttttacgaaa aaggatgaat aaggttgttt
    14461 gtgtccaagt aatgggggtt aatccggcct ctttgcttgg aatgcaagga gggaagtttg
    14521 ttaatgaaaa tttttcctgg gacattattg taaagaaata taacaatttc ttttctgaat
    14581 tatatagaga tatgtctgaa taaacataaa tggagtttat tatagaagta gagaggggaa
    14641 atagactaat gggaaataga ttttttcaaa taattaattt gaaatcattt tttgcctata
    14701 taataatcac gttattaagt tttttgatgt tagtatatat aatggagcta tgggatgttg
    14761 atttaaatgt tccgcttgta tatttaggtg atggtttatc agcaggaatg ttagtgaaaa
    14821 gcgtaattga taatggttgg tttttggaaa atcaatattt aggagcacct ataggtgcga
    14881 atttatatga ttatccatta tctgacggat ttcattttct tttaatgaaa ttaatagcct
    14941 tgtttcaccc tgattatgca tttgtaatga atttttattt gatacttaca tttccgttta
    15001 cagctatagt atcatttttt gtttttcgac aatttaacat ttcttatatt ccagcctttg
    15061 ttggtagtat gctgtatact tttttgccat accatttttt tcggtgggca ggtgggcata
    15121 tctttttggc tgcatattat acagtaccat tggtagttat ggttttttta tggatgtttt
    15181 gtgagaaaaa ttttctcttt ttctataatg aggacaaagg caagtataag tttgagttat
    15241 ttagttttaa atccatggtt agtataattg cttgtctttt aatctcatct agtggtatat
    15301 attatgcatt ttttacgtgt ttttttcttg ctgttcaagg tttagctata tctattttta
    15361 ggaaaagatt tatacctata gtagttgctg gtttcttaat atctacggta tgtataggag
    15421 ttttggctaa cgtagttcct aatataattt atacacatta taacggggaa aatagcgagg
    15481 ttggaaaacg aagtccatta gaagccgatc tatatggttt gaagatttca caattgcttc
    15541 ttccgatttc tggacataga attagttttc ttaaggagtt gaaggagaaa tataacagtt
    15601 cttttccttt ggtcaatgag aacgataatg catctttggg gattttagga agtactggtt
    15661 ttttaatctc tctatatatt ttcttattta gacgtgagca aaaaaatgat attaagcaaa
    15721 atttaagttt ccttaatgtt tgttcgatac tctttgcttc aataggtggt ttaagtacgt
    15781 tattttcaat tttgatatct cctcaaatta gggggtataa tcgtataagt gtatttatag
    15841 cttttttttc tatttttatt ttggtactag tatttaacga ctttaaaaaa aagtttatta
    15901 gtaatagagc tttgaaaata gtttttaata ctttcttgat aataatttgt ctagtgggaa
    15961 ttttggatca aacaaataaa aattttttct taccctatga aatattggaa aaagaatata
    16021 aaaatgataa ggagtttatt cgaaaaattg aagtttccct accaaaagga gcaatgattt
    16081 ttcaaatgcc ttatgtttct tttcctgaac agcctcctgt aaatcaaatg ggtggatatg
    16141 atttggcaaa agggtattta cattctacca acttaaaatg gaactttgga gcaacaactg
    16201 gaagagaaag tgatgcatgg caaaagaata ccataaataa aactttggat gagatgattg
    16261 aaacattatc tttagcaggt tttaagggaa tatatattga tcggaacggt tatgcggata
    16321 aagggattga gatagaaggg aaactctcat caatacttaa aactaagccg ttaattagtg
    16381 aaaatcaaag attatctttt tttaatatgg agacgtataa taaggaagtt gaaaataaat
    16441 acacaaaaaa tgaattgaat ttaaaaaggg ataatgctct acatcttgtt ttattaacat
    16501 ggaaaaatgg attctatggt ttagagcaga atgaaagtgg tagctggcga tggagtcagg
    16561 ataagagttc gatgataatt aataattatt cttcaaaaga gagaattgtt actatcgaaa
    16621 tgtcttttca aacaggatat gaacaattgt ctagtttgtt tatagaaacc ccgacgttta
    16681 aagaagagtt aaaagtaaat aataaagaaa aaaaatatat aaaaacaata cggattcctt
    16741 cgggaagtta cattattaaa tttactagca atgctgagaa ggttaatgtg cctgatgaat
    16801 cacgtaattt attttttaga gtaaacaact ttaaaataga ctataaataa tagcatacac
    16861 taaaattttt gtagaggata acatatggaa aataaagtta ttaacttcaa gaaaattatt
    16921 gattctcgag gttccctagt agctattgag gaaaataaga atatcccatt ttcaattaag
    16981 cgtgtgtatt acatttttga tacgaaggga gaagagccaa ggggatttca tgcgcataaa
    17041 aaattagagc aggtacttgt ttgcttgaac gggagttgcc gtgttattct cgatgatgga
    17101 aatataatac aggagataac tcttgatagt cctgcagttg gtctttatgt aggacctgct
    17161 gtttggcatg aaatgcatga tttctcaagt gattgtgtga tgatggtatt agctagtgat
    17221 tattacgatg aaacggacta tattcggcaa tatgataact ttaaaaagta tatcgctaaa
    17281 attaatctag aaaaagaagg ataaactgta atttcgttta gaatattatc gataatatat
    17341 gtgttattat taaggagaga aagttaatgt ctagttctag tgaaacttgt tttgttcacc
    17401 ctaacgcaat tgtagagacc aaaaagatag gaaataatac gagaatatgg gcctttgttc
    17461 atattcttcc tcaggcaatg ataggggata attgtaacat ttgcgatcat tgttttattg
    17521 aaaatgatgt gtttattggg aataatgtga ctgtgaaatc aggtatctat atttgggacg
    17581 gagtgtatat tgaagataat gtattcttag ggcctaatgt tgtatttact aatgatgttt
    17641 tcccacgaag taaggtgtat ccagaatcgt ttgggagaac tatagttaag aagggtgcca
    17701 gtattggtgc taatagtgtt attgttgcag ggaatattat aggggagtac gctatggttg
    17761 gggcaggatc tgttgtaacc cgtgatattc ctgattatgc attggcttat ggtaatcctg
    17821 caagaataaa gggatatgta tgccaatgta cttctaaatt aaaatttata gataatcaag
    17881 ctgtatgcca atgcggaaaa agatataaat atgctgatgg tattgtttct caattaatta
    17941 tttaatgtaa taggtggggt atgatgattc cttttttgga tttaagacaa ataaatatga
    18001 gatatcaaaa agagattcaa caagcaatga atagagtgct tgaatcggga tggtatattt
    18061 tagggggaga agtggatgat tttgaaagaa agtttgccag ttattgtggt gcaaaatatt
    18121 gtattggggt agcaaatgga ctagatgctt taacattgat tattagagca tatgatatag
    18181 gattaggaga tgaggtaata gttccttcca atacctatat tgcttctatt cttgctattt
    18241 cagcaaatgg tgctactcct gttttggttg aaccagatat aaatacatac aatattgatc
    18301 ccctaaaaat tgaagagaaa ataacttcgc gtacaaaagc gattatggtt gttcatttat
    18361 atggacaatc atgcgatatg gaatcaatca atttgatagc taaaaaatat aatttaaaag
    18421 taatagaaga ttgtgcacaa gcgcacggag ccatttataa tggaaaacgg gtaggaagtc
    18481 ttggagatgc ggctggcttt agtttttatc cagggaaaaa tttaggagca ttaggtgacg
    18541 gtggcgcgat cacaacaaac gatgctgaac tagctgaacg cttaaatgtt ttacgtaatt
    18601 atggttcaca taaaaagtat gaaaatcttt ttaaaggtgt taatagtcgc ttagatgaat
    18661 tacaagcggc gatccttagt ataaaacttt cttacttgga tgatgataat caaagaagac
    18721 gggaaattgc agcatattat ttagaacata taaagaatcc gtttattcat ttgccaactg
    18781 ttacggatga taaggctcat gtttggcatt tatttgtagt tcgagtaaag gaaagagaag
    18841 catttcagta ctatttggca gaacaaaaca ttcaaaccct tattcattat ccgattccgc
    18901 cacataaaca aaaggcttat agtgagtggc agcaagaaag ctttccgatt tctgaacaaa
    18961 tacatagtga ggttgttagt ttgcccataa gcccagttat gagtagagag gaagtcgaaa
    19021 gggttgtgga ggctgttaac aggtatggat actagaaaaa agttttctat tcttgttcct
    19081 atttatttta atgagctcaa tatcccgtat acagtaccaa ggttgcaaaa tttgcaaaat
    19141 atattacctg agtatgactt agaatttgtt tttgtagatg acggttctca ggataattcc
    19201 ttatctttgc ttttagaggc aaaaaagagt gacgaacgaa tcaaagtaat taaacttagt
    19261 agaaattttg gttcaatgtc tgctatttct gcgggacttc attacgttac aggagattgt
    19321 gtaggaatta tcgctgccga tttgcaagat ccaccagaat tatttgcaga gatgataaaa
    19381 agttgggagt cgggaaagaa aatagttatg gcgacccgtt ctgatcggga agagtctttt
    19441 tcgcaaaagt tgttttcaaa ctcctattat ttccttatgg ataagtttgc aataaaaaat
    19501 tatccgaaag gaggttttga tttcgttctt ctggataagc aagttgtgca agaattgaat
    19561 aacataaacg agaagaatac gaatatcatg agccttatat tctggctagg acatgaacag
    19621 gactttattc catatgtaag gcagaagaga gaattaggca aatcccgatg gacaatgtcg
    19681 aaaaaaataa agctatttat tgattcattt gttagttttt cttatgttcc aattcgcttt
    19741 atgtcattag ttggtttttt tacggcactt cttagttttt tatatggtat attcgctgtt
    19801 tttaatacat tgacgggtaa tattactgtc cctggttgga cgtcggttat tggcctaatt
    19861 acttttttgc taggtttaat catggttatg ttaggaatta ttggggagta tttgtggcgg
    19921 gtattagatg aagcgcgaaa tagaccgcat tatataattg acgaagtata tgaataagga
    19981 attttttcgt tttcttattg ttggtggact aaatacggga attacatatg gaatatatct
    20041 tgttttatta ttaggattcc cgtatgtatt agcgtactct ggttcttata ttattggagt
    20101 ttttatatcc tattatttaa attcgaaaat tgtctttcaa acaaatttta gtataaaaaa
    20161 aatgcttcag ttcccattgg tttatgttgt gcaatatgtc ataaatacaa tgtttcttta
    20221 ttttttggtg caaatgaaca ttagtgagaa attagcacct attttggtgg ttattttatc
    20281 tattcctatt acttttattt tgagtaagta tatattaaaa aagtcttaaa gtatagtttt
    20341 tctaaggaga tgaggattgt tgaaagggat tattctcgct ggtgggagcg gaacaaggct
    20401 ttatccatta acacgtgcta tttctaagca actgttacct gtgtatgata aaccgatgat
    20461 ttactaccct ttatctgtac ttatgctagc gggaattcgt gatattcttg ttatatctac
    20521 ccctgaagac acaccgcgtt ttgaacaact gttaggagat ggaagtgagc tcggtatttc
    20581 gctttcttat gcaattcagc cttcgcctga tgggctagct gaagctttta ttataggtga
    20641 agattttatt ggacaagata atgttgcact tattttagga gataatatat tttatggtca
    20701 aggcttcact ccattattac aaagagctgt aaatagaaaa aagggtgcaa caatatttgc
    20761 taatgttgtg aaagacccgg aacgatttgg tgttgtcgaa tttgatgaaa ataataaagt
    20821 tttatccata gaagaaaaac ctgtatatcc taaatctaat tttgctgtaa cgggacttta
    20881 tttctatgat aatgatgttg ttaaaattgc gaaacaaatc gaaccttctg caagaggaga
    20941 attagaaatc actgatgtaa acaaaatata tcttgaaaga ggagatttaa atgttgaact
    21001 tttagggcgt ggttttgcct ggttagatac aggaacacat gaatctcttc ttgaagcttc
    21061 ccaatttata caaacaatag agaaaagaca ggggcttaaa gtggcttgtt tagaggaaat
    21121 tgcttactat aagggatata taaataaaga gcaattaatt agattggctg aaccattaaa
    21181 gaaaaacgag tacggagcat atctattaga actcgcagaa aaaggctccc tacaaaccgg
    21241 atcaataaat acaaaggaag cggtgcttta tggataaaga agaaaagata aattcgattc
    21301 ttgttacagg tggagccgga tttataggct caaattttat cccttatttt ctagaaaaat
    21361 ataataatta cagaataata aacttagatg ctttgacata tgcaggaagt ttaaacaacc
    21421 ttcaagaagt tgaacatcat ccaagatata aatttgtaaa aggtgatatt aataaccgtc
    21481 aattattaga atatcttttt gaacaattta atataaaagg tgttattcac tttgccgcag
    21541 agtcacatgt tgataattca attaaagggc cagacatttt tattgaaacg aatgtgaaag
    21601 gcacatttac attattggag actgcgcgta aattttggat gattgctcct tttaagtatc
    21661 gagaaggata tgaacaatgc cgctttcacc atatttcaac agatgaggta tatgggacat
    21721 taggagaaga aggttatttt acggaagaaa caccttatgc ccctaatagt ccatatagtt
    21781 ctagcaaggc tagctcggat atgatagtac gtagttattt tcatacatat gggttgaatg
    21841 tagtaactac aaattgttct aataattatg gtccaaagca gcatgatgaa aaattaatcc
    21901 caactgttat taggaaagca cttgcgaatg agcatattcc gatctatgga gatgggaaga
    21961 atgtacgtga ttggctatat gtactagatc attgtcaagc tattgatgca gtttatcatc
    22021 gaggagtatg tggtgaggtt tataatatcg gttctagaaa cgagcaaaat aatttacaga
    22081 ttgctcatat gatttgtgaa ttgctagata ggatgaaacc tatagcaaaa ggaaggagtt
    22141 ataaggaatt aataactctt gtacaagatc gccctgggca tgatcgtagg tatgcgattg
    22201 accctaaaaa aattgaaact caattaggct ggaaagcaga agaaaatttt gaagatggga
    22261 ttagaaaaac ggttcagtgg tacttaaaca aatatgaata agaaacattt tttaccactt
    22321 tttatttaaa aggaagttgt ttaacctata taagttgaat ttaattttta catcttaata
    22381 caaagtctat caatgactat ctcaggcatc tggttaatag aggaaataaa cgcttgtaca
    22441 tgtttgcgga tgtcttggac agatttgtgg aacacattgt aaatgacggc acttttcagc
    22501 tatttccaca atccttcaat caagttcatt tccgggctgt atggcggcaa gaatacaagc
    22561 tctagccggt tctgattttc ttctaaaaaa ggctgaatga gacgggcatg atgaatgcgg
    22621 gcattgtcta acaccatgac aatcttgcct gtcgggtact gtttcggcac atgctgaaga
    22681 aaacgcagaa aagcttctgc atcgtattgt tcctcttcta cgcagtgtac gcggcctgtt
    22741 tcatagttca gtacgccaat gagcttaact ccgtgatgct tgccataagt cggaatgatg
    22801 cgctgctttc cgcgcagaaa ccaggtgtac tgcactgcct gataatcacg aatcatgcac
    22861 tcgtcctgaa acagaagatg agcgatttct tcatccatca gtttttttta aagcaggaaa
    22921 tgtttcttcc cggaaccccc tttgcttctc agggtctgct tgggcaagag tatacgttgg
    22981 cttggtgtag ctcaggccaa ggcttccgag cagacgcgac atgccacgta aggtgtaggt
    23041 tttctgccat ttctgttcga caagtgccac aataagagcc aatgtccagt tgtagcgggc
    23101 ttcaaatcct acatctaccg gaagatgatt gacgatgatg tctaccagtt cctgttcttg
    23161 ttctggtgtc agtttgtgag gcgcaccggg cgatgcatgg cgcacgagcc cctctaagcc
    23221 ttgttcccgg taggctttga catatgtgcc caccgttttt ttattccggc caatgatggc
    23281 actgatttgc tcatatttgt atccctgcag aaataaagag atggcttggt agcgttcata
    23341 cattcgcttg tcttttgtct gtttcatcgc ttgttgtaca gtttgcagtt ctgttggatg
    23401 aatattcatg tctatttctc ctatcccgtt cctagtttgt ttgcttctat tgtaacacag
    23461 gatagaagaa gaatttattt aattcaactt atatagaagt atatttaatg taaggagaca
    23521 ctataaaatg aaactcattt tactttccgg tggctcgggt aaacgattat ggccattatc
    23581 taacgattcg cgatctaaac aattcttaaa agtactcaaa aatgataaca atgaatttga
    23641 atccatggta caacgagtat ggaaccagct tcatacagtt ggtttagcag aagactctta
    23701 cgttgccact agcaaatcac aagtagacat gctgcatgcc caattaggaa ctgaagttcc
    23761 tcttattatc gaacccgaac gtagagatac attcccagca atcgctttag cagccacata
    23821 tctatactcc atggaaggag tacgagagga tgatgtgatt tctgttcttc ctgttgatcc
    23881 atatgtggaa tcgcgttttt ttgatcgggt taaagatttg gaaacagcac ttgtacaatc
    23941 atctgcagag ttagcgttaa taggggtaaa accaaccttc ccttctgaaa aatatggcta
    24001 cattgtcccc aaaaaaggtg aacatgatgt tgtagcgaat gtattagctg ttgattattt
    24061 cgttgaaaag ccaagtacaa gccgtgcgca agaacttatg aagcagcaag cattctggaa
    24121 ctgcggaatt ttcgcattta agttgggata ccttatttct cttttaaaag aaaaaaaatt
    24181 accaactgat tatgaagaaa tgcttcatac atataaccag ttgcctaaga tcagctttga
    24241 ttacgaagtg gtagaaaagg ctcaaaatat tattatgctt ccatacgaag gcgaatggaa
    24301 agaccttgga acatggaata cactaaccga agagatgaat acgaatcttc tgggaaaagg
    24361 tatcattagc gaggggtgtg aaaacacgca tctgattaac gaactcgata ttccagttac
    24421 cattctagga atatctaatg cggtgattgc agccagcccg gacggtattc ttgttacgga
    24481 taaagaagcc agtccccgaa tcaaagatat tatgaaaaac tttaatcagc gcccaatgta
    24541 tgaagagcgg cgctggggat ggtaccgtgt actggatcat acgaaagtag agaatggaaa
    24601 tgaagtttta acgaaacgca tcggggttca tgccgggaaa aacttaagtt accaaattca
    24661 tcataagcgg agtgaagtat ggacgattat ttccggtgaa ggacaatttg ttttaaacga
    24721 tcaattatat catgtaaaac cgggagacgt cttgcagatt cctgtgggtg ctaaacatgc
    24781 cattcgtgct attaccgatt tacagtttgt cgaagtacaa acaggcagtg aattgatcga
    24841 ggaagatatt attcgcctgt gtatgacatg ggaagaaacg ctagactgtt gcaaggattg
    24901 catagtaaaa gttattcgct gatattctct gaggcccttt gggagataat cttcaagggc
    24961 ctgttttttt aggagggatt atcataaagg ttttatttga gtcacagcct ttattaggac
    25021 gacgcaccgg cattgggcgt tatgtagaga gactaacggc cagcctgcag gagaatcagg
    25081 atattgattt gttttattgg tttaatcaac agttcaatgt aaaattattg caaatgttag
    25141 atgttccgtc gactaagatc agaaattccc ggtatttcta taaggtgatt cggcgtttaa
    25201 tgaagcctaa ctttttgcat gacttgcctg tcgacttagg ggaatcgttc gatatttttc
    25261 atggaggtag ttgtattact tatcaaacca caaaggcaaa aaatgcactt accattcatg
    25321 acttagcttt tcttcagttt ccagaggtgg ccagtgagca gacggatcgc catcactcct
    25381 tatggctccc ttattcaata aaaaaggcag accatattat tgctgtatca cagcatacta
    25441 aagaggatat tattcgctat tatgatgtac ctgacgaaaa aatcagcgtc atttatttgg
    25501 cggcagacga ccagattaaa aaagaggaca ggcctttaaa ggaagaagta caagcgaaat
    25561 ataatttacc ggaaaaatac gcgttgtatg tagggacaat tgagccaaga aagaacatcc
    25621 catttatgct ggaaggatat gctcttgcta aacaaaaata taaatttcct cataagcttg
    25681 tgattgctgg ggcgaaaggg tggaagtacg aaaaagtata tgagacgttt gaaaaatatc
    25741 ggttgcataa cgatgtaatt tttactggtt atgtggaaga tatggactta cctgttctgt
    25801 atgagaatgc ggatgtgttc ctgtttccat cacgatacga aggatttggt attcccgtat
    25861 tggaagccat gcaatgtggg gtagccgtta ttgcttctaa tgtatcttct cttcctgaaa
    25921 ttgtaggaga agcggggaga ttggtatcac tggagaaacc ggaagaattt atcgatagta
    25981 ttggtgagct attgacaaat gaggcgaaaa gaagagaata cgaagaagcg ggcagacgac
    26041 aagcccggat gtttagctgg aaaaaagccg cttccgaaac ggttactgtc tatcggagct
    26101 tattgtaaga agaaagtaaa aaaacaggag ttatatatga aaatattaca agtaaataaa
    26161 ttttatcccc cggtcattgg aggggttgaa aaagttgtat atgatttggt agaaggaatg
    26221 tgttcacttg cggaaatgga ggtgcttgtt gctaatactg aatggaaata tgtacaggaa
    26281 atcgaacata aggcaaagat acatagggtt ccgagtattg gcacttactt ttccatgccg
    26341 gtagctccta cgtttccgct ttggcttaaa aaaattaaga ccgatattat acattttcac
    26401 tttccttttc cgttaggaaa gttgtcttat ttgcttgtag acaagatagc aaatataccg
    26461 gcgaaaacag tcgtaacatg gcatagtgat atcgttaggc aaaagcgttt tttgaagctt
    26521 tatcaccctt ttctaaagag atttcttgaa aaagtggaca caatcattgc gacttcaccg
    26581 aatatggttg aggcctctcc atacttaaaa gagcataaag ataaatgtcg ggtaattccg
    26641 cttggaattg atgttaaaga atgggaaaaa acagacaagc tttttgagaa tgtgaaaaag
    26701 gtaagagaag aggtggctat aaagcctatt attttgtttg taggacgtct tgtttattac
    26761 aagggtgtcg aatatttaat tgaggcgatg acagagataa atgcctccct ttttcttgtt
    26821 ggcgaatggc ctttaaaacc gttattacaa aaaagagctg aggaactagg aattacggaa
    26881 aaaataaact tcttgggagg ggcaagcaaa gagcaattag tgacatatct gcatgcttgt
    26941 gacattttcg ttttaccttc tgtagagcga agtgaggctt ttgggattgt ccaacttgaa
    27001 gccatggcgt gcggaaagcc tatagtaagc acaaatttag ctacaggtgt gccatttgta
    27061 aatcaggatg gaaaaacggg aattgtagta ccaccaaaag atataaaatc cttgacacaa
    27121 gctcttactt tcttaattga aaatgaatct gttcgaaagc aatatggtga acgagggaaa
    27181 gaaagggttt atgagcattt cacacgagag aaaatggtac aaagtgtata tacgttgtac
    27241 caggaactcc tggaaggtgg aacaacataa tgggagatat ttatgtaaat gctcgtttca
    27301 tgaatcaagt tgttaccgga gtacaacggt atgcttggga gattactaat catttacggg
    27361 atagagttca tatcatacag ccgggcaaga gcttttccgg agaagcaggt catttttggg
    27421 agcagattgt acttccgggc agaatgccgc ggaatgctct gctttggtcg ccagcggggg
    27481 cggggccttt attagtatct aagcaagttg taacgctcca tgatattgcc catcttgaac
    27541 acctcaccat cctcgtggtt ttgcagtgtt tctcttcacg gcaggtctcc tggcttcggg
    27601 tctgacgaac aaccgccccc ttcccatttc acaggcagaa atagtgggtt taatatcagc
    27661 agtgttcttc ccttcacagt ggcgggaccg cgtcggattt gcaccgaact tcccttttaa
    27721 gttctccatt ccagcatctg gtggaacttt gaacaccgta aagtttacat atacagttgt
    27781 aagtgagccc atgataacat gaatttgaaa ataattctac tggtaaacac ttattttttg
    27841 aaaaattata gactttagta caggaaagaa atcagaatac tagtaacagc gccaacctaa
    27901 tttataagac tcaggcttac tattactttc atgtagatcg aatcaaaaga aataagaaac
    27961 cctgcctttt ggcagacagg ggcgaaattc aactatttaa ggcgattaaa gtttggtatg
    28021 ggtaccatca cattacggta aattcccgga ttttccgcac ccgcaaatcg cgactgtttt
    28081 cggttcttca atattcacaa tgaacggctg ttttcctgtc cctttgtgag agccatcaca
    28141 atacggaggg ttcccagtca aaccacaagc acaataagct ttttttccgg gtttctcttg
    28201 gattacatag ggttgcttcc tatcatacat agccatctcc attcctccta tatccatctt
    28261 ttttgctctt tcaacgttcg tattgtgatg agaaaaaggg tcgatttacc aattccattt
    28321 tttcctaata cgagacggaa atattcatcc gttatttaat caatcgtaga aacaagaaga
    28381 agcggaacat ggaacttatt tgattttatc tttttgcaaa cacaacattg gtaattttgc
    28441 acattatttg attctaaagc agggaattct ttttcaaatt tccatggtcg aagccgtctc
    28501 atttggcaaa tatatagcta ccgattaagg ggttaacaaa cggttatttg gcaatactgg
    28561 ctcttatcat cacaatgata aggagcggat tatgttatga aaaaatcact gattacaaac
    28621 ttacgaatga agcattacga aaggaagagc gtgcgatttc tgatgctttt ttccggcagc
    28681 gtgtgacggc cgttcgactg attcttgaag gtttttctac ggtaaaagct gcagaagtac
    28741 tgggcatttg tcactagtct gagacgcctt agaaaaaggc gccgctcacg taaataacac
    28801 ctgaaatttt tcaaacgaag aaagggaact gacccttccc tatctaagtt aaaaatatgc
    28861 ttaagaaatt ttcgaaatca caagtatgga taattgcttt agtggtctat gtgctaagta
    28921 ccattaatta caaaaatcct tctacacttg ataagatatc cattactttg gcatgtatct
    28981 tatcagctct tgtcatctgg aatttcgtat tacacttata taaagaaagg attgaaaaat
    29041 gaactatacc tttaacagta caaaagagtt aaaacagttt atcgcaaagg aagtcttgag
    29101 ctcggctgaa gctattgaat acctagggat tagtcgtgca cgtctaagcc agttaattaa
    29161 gaacggcaaa cttatcccca tcaaaaaact gcaacgggat agtctgttcc taaaaatcga
    29221 tgtagagaaa aaaaagtaag agcttgaaga gttaaggaag aaatacagac catatgatta
    29281 aaaataagac ccggctacac cgagttattt ttgttctggc atccatgtga atacgtagtc
    29341 aggtttcgaa ttctttagga caagctgacc gttttctgta tgtacttccc gtttgcctgt
    29401 atcgataagc ttctgaaggt cttcgggtaa ggggatattg ccgtttcctg ttgcggccaa
    29461 gtaaaggaat ctctatctct gtctgagctc acctttcgct gtgaatgtgg ttttgtggca
    29521 aacagggact agaatgctgc taccaatgtc aaaaatgaag gattgcgact gttaacataa
    29581 ctataaatag agcatggaac aggctcaata gctaagtaaa tttcgtactg ttaggtatga
    29641 ttaccttaga agcccccatc tccaagcgaa gcgtaggtga cgggtaattc acattgaata
    29701 taggtttttg tctatgtcat aaacctatat ataaacataa tttatgatga gcgctaacac
    29761 tcgaaatata aaggaggtat actcgatgta ctggtatcat gatccaaatt atgtgcagca
    29821 gtatagtccg gacatacaac aatatgatta ctacgtttat cctgaccttg agagacaacc
    29881 acaactattt gggagagtta atcaacttga aaggcgtgta aatgaactaa ccttgcaagt
    29941 aaatcagctg caaaatacgg tggaacgtca tacaagaagg ctaaatcggt taaatcaacg
    30001 tctacgtgta gttgagaata ggctgcaaat accttttact ccttatgaag gtggatttta
    30061 atcaatccaa gaccttaaaa aacctaatat aggaaaaatc ctcatttagg gttcttaaat
    30121 cgttaatgta caaaagaatt gtaaatctac agcttgatgc tcaacgtccg ataagctctg
    30181 ttatgcataa tctgttatgc ataaagagat tatcggacgt aagcaaacaa atgtaactta
    30241 cttactattc tccatcacgt ttttatggtg caatttttgt tcccataagt gaaggaagtg
    30301 tataggatgt cagattattt ccaattggat taattccagt tgtg
//
