LOCUS       BGC0000803             19797 bp    DNA     linear   BCT 28-MAY-2009
DEFINITION  Lactobacillus rhamnosus strain GG exopolysaccharide gene cluster,
            complete sequence.
ACCESSION   BGC0000803
VERSION     BGC0000803
KEYWORDS    .
SOURCE      Lacticaseibacillus rhamnosus GG
  ORGANISM  Lacticaseibacillus rhamnosus GG
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Lactobacillaceae;
            Lacticaseibacillus.
COMMENT     On Apr 6, 2009 this sequence version replaced EF690379.1.
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2022-11-07 20:38:14
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 19797
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..19797
                     /culture_collection="ATCC:53103"
                     /db_xref="taxon:568703"
                     /mol_type="genomic DNA"
                     /organism="Lacticaseibacillus rhamnosus GG"
                     /strain="GG; ATCC 53103"
     subregion       1..19797
                     /aStool="mibig"
                     /contig_edge="True"
                     /label="Saccharide"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..19797
                     /contig_edge="True"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            4..924
                     /gene="wzd"
     CDS             4..924
                     /codon_start=1
                     /gene="wzd"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 45.3; E-value: 7.2e-14)"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to polysaccharide co-polymerase"
                     /product="Wzd"
                     /protein_id="ACN94846.1"
                     /transl_table=11
                     /translation="MNEQIDLAQLWNVFKRSFLAMIVFGIIGMAAAYFGAKAFIAPKYE
                     SDTSLLVNRKQDNDPNMQLNAQQADIQIINTYKDIITRPVVLQAVAEDLTSPQRVMVKK
                     AKPAVYGTRYNAATGTRERYVTEEAQPAKYKLKPAKYSNISEEDLTKMVSVSTQQNSQV
                     FTVNVKDTSPVRARDIANEIAKVFEKKIAKIMSISNVSVVSRATANTIPVSPKLKLLSI
                     VGLALGILIALSWGLVRELTDQTIKDIDFITDDLGLVNLGIVNYVVRMKDMDQAIQQSR
                     ATDSGNDVQDDLDGIDFPQRSRRRI"
     misc_feature    4..18741
                     /note="exopolysaccharide gene cluster"
     gene            935..1693
                     /gene="wze"
     CDS             935..1693
                     /codon_start=1
                     /gene="wze"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1216:exopolysaccharide biosynthesis domain protein
                     (Score: 210.4; E-value: 7.3e-64)"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to autophosphorylating tyrosine-protein
                     kinase"
                     /product="Wze"
                     /protein_id="ACN94847.1"
                     /transl_table=11
                     /translation="MMQLSFSKLFHRHQEDQETQKNGVMLVAFAEPKHVVSEQFRTVRT
                     NIEFAGAALDRCQVVMFTSSAMSEGKSTVSANVAVTWAQAGKKVLLIDADLRRPTIHAT
                     FRTLNIDGVTTILIGKDEAGAVVEETFVDNLSVITSGPIPPNPSELLNSKRMANLLNWA
                     RENYDIIVLDTPPVLAVSDVQVLVPKTDGVVVVANMGKTLKGDLRRTVEVLKLANAKIL
                     GSVERVKAKHGDRGYGYGYGYGYGTNTGKK"
     gene            1743..2966
                     /gene="wzy"
     CDS             1743..2966
                     /codon_start=1
                     /gene="wzy"
                     /note="similar to repeat unit polymerase"
                     /product="Wzy"
                     /protein_id="ACN94848.1"
                     /transl_table=11
                     /translation="METNNLEDSFQPFLVKTYLFIYFWLVIIFGFTAESMISPVDQPSA
                     YPSFVSFGNKTAYFLASLLLVLGFLKRRSLLNWLITGPLFLVIVYGYLFVNQQVAVVAF
                     IFLVWSSQTVSFRSLVRIDLFARIIVTISLFVVNNLQLLPVSPIIQLGVYSRFSFGFHH
                     PNALGMYLMMISLEMFYLYARKSVKPIVLLILSGILIFVLTRSRGSLISVMSFVVLVTV
                     FNTFKSISFRKLLYSFCILVPLICFLGSLTISIFLPSSSKVFQTLNEWMSGRPELLKLV
                     YDYYAQKSFFGGDIAELANAFYSWSINVRYLYVDNQYMYSVMIFGWFGAVLEVLYSTYC
                     GIRAKIFGDSYLLFWLTAIALFGLVETKLVTLDMALPFMCLGSLTEGVTKDKKVLSAEQ
                     GHLQAKAN"
     gene            3015..4145
                     /gene="glf"
     CDS             3015..4145
                     /EC_number="5.4.99.9"
                     /codon_start=1
                     /gene="glf"
                     /note="similar to UDP-galactopyranose mutase"
                     /product="Glf"
                     /protein_id="ACN94849.1"
                     /transl_table=11
                     /translation="MKLLVVGAGLFGATVAHERALKGDQVDVIEKRSHLAGNIFTEEVE
                     GIQVHRYGAHIFHTSNKKIWEYINQFSSFNRYTNEVIANYKGEIYNLPFNMNTFNKMWG
                     VITPAQAKAEIDKQRASMAGKVPQNLEEQAISLVGKDIYEKLIRDYTAKQWGREPKELP
                     SFIIRRLPVRFTYDNNYFNDLYQGIPEGGYTQIVEKMLDHANIKVHLNTDFLTHKEEYL
                     TRYDQVVYTGMIDQFFDYQLGALEYRSLRFETEVLDVDNYQGNAVVNYTDSDTPFTRII
                     EHKHFEFGKGNQGKTVITREFPAEWSKGDEPYYPVNDTKNNHLFTEYRDLATKKYPQVA
                     FGGRLGLYRYYNMDQVITAALQFVKGKFFARIKTEI"
     gene            4188..5624
                     /gene="wzx"
     CDS             4188..5624
                     /codon_start=1
                     /gene="wzx"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to polysaccharide repeat unit transporter"
                     /product="Wzx"
                     /protein_id="ACN94850.1"
                     /sec_met_domain="Polysacc_synt (E-value: 6.2e-55, bitscore:
                     176.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGELYDSSKELFMEYGVSGFVLLLPIITIPYVSRVLGPTGIGIN
                     AYTNSVVQYFILFGTLGITVYGNREVAYERDDPQKLSNVFWELTFLKFLTTGVAVIAYL
                     TFIFLSKQYRVFYLIQGSLLLASAIDVSWFFQGLEEFRITVVRNTFVKIISLVLIFTLV
                     RTKNDLWIYVLILGGSQLIGNLTLIPYLTRYVKWPVLRKMRLGRHLKPTIGMFIPQIAS
                     QIYLQVNKTMLGAYIGVEAAGYYDNSDKIIKILLAIVTATGTVLLPHVAHSFARGDRKA
                     VFSSLSKSMHFILLLAFPMSAGLASISPVFTNVFFGIKFSAVAVLLAIESLVIILVGIS
                     NAIGIQYLLPTNQTRPFTVSVALGAIVNIFLNIPMILLWGTVGAMTATVISEAAVTAYQ
                     LVYVRKQMDISLLFTETWKYLLSASLMGAYIFWYMHFMPFGNMVKLVTTILLGTIIYIL
                     ILLLLKPRHLIEMVSSIRQR"
     gene            5646..6245
                     /gene="welJ"
     CDS             5646..6245
                     /codon_start=1
                     /gene="welJ"
                     /note="putative glycosyltransferase"
                     /product="WelJ"
                     /protein_id="ACN94851.1"
                     /transl_table=11
                     /translation="MGNLLIKIIIAAHKPVQVPNDQTYFPVYVGSKFHESTPKGFLRDD
                     SGKNISWKNPHYNELTAIYWAKYNLDFDILGLVHYRRFFVNKKKFGSRSYDLIKQSDIK
                     KLMAHTDVVVPKKRHYYIETIESHFYHSHDRQGLDCLKKVMEEQPEAYRFAFRKVLNAR
                     SAHMFNMFIMKKKVFQDYTNWLFSILDQVDELLDFK"
     gene            6474..7610
                     /gene="welI"
     CDS             6474..7610
                     /codon_start=1
                     /gene="welI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 111.2;
                     E-value: 1.1e-33)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative glycosyltransferase"
                     /product="WelI"
                     /protein_id="ACN94852.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 3.4e-26,
                     bitscore: 82.0, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTLVVADFLPASGVTTFVENAFLKQRQGFSFSALAIAGDESNK
                     LHFEKAGWTFTDISPANKNYIRHIKDWLKFARRNKHAFDIVYFNYSASWNILPIFFCKF
                     IMHAKIVVHGHNTYFGTEIHGVKKFALTVFHLIGKQIAATFLIDSFVAVSNEAAKWMFP
                     SRILRKNRVEVIPNGIDLSDYTFKRATRVKVREALDVQNKIVYATIGVLEMRKNISFAL
                     DIFAAIIRRNPNSVLLVIGDGTQREMLKQKARRLELGDSVRFLGRRKDLAQLYNAIDVL
                     LFPSLNEGLSFTLIEAQANSLPVYVSDRVPLGNYLPNLVHVVKLSESSDSWSKRITATE
                     KHVRVDESKRMKKIGYDQLDMREHVLHLLEALQGGNTE"
     gene            7607..8542
                     /gene="welH"
     CDS             7607..8542
                     /codon_start=1
                     /gene="welH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /note="putative glycosyltransferase"
                     /product="WelH"
                     /protein_id="ACN94853.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.8e-27,
                     bitscore: 85.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFDHLVILMSTYNGERFLKQQLDSIVQQDYENWDLIIRDDGSTD
                     STQQIIDDYVLKDNRIHSFPDSAGNRGPANSFLMMLTSISAPLFMFADQDDIWYPNKVG
                     LTVGSYMQQTSSASVPTLVFTNMDTIDASGTLIQSNIVPENARVSVNTILVTNIVTGCT
                     VLINKSLADRIRLSDTRSIVMHDWWMAMIAAFLGNVVYLPTATIGYRQHGDNAVGVNHS
                     FRSRINKALNYSNQRKLFSKQMAQIKLLDTRFGKNLSVSRKVELDSLISIQRSKRFLSK
                     FSWLLRHRAKKTSLVGTLSFYYLFLTTNVE"
     gene            8603..9619
                     /gene="welG"
     CDS             8603..9619
                     /codon_start=1
                     /gene="welG"
                     /note="putative glycosyltransferase"
                     /product="WelG"
                     /protein_id="ACN94854.1"
                     /transl_table=11
                     /translation="MIEFDGYNSKSFDAGFKARADVKYFSNRMGIKTAEIPATRVNLKI
                     NRELQRLRAVRSLSKKLSADQSVLIQYPLPFNSFDYSLLHKTLLKHNAKCIFLVHDLIS
                     VQGQAKNVSIKQEIEELKRADFLIVHNQAMQNFLEDQGLSQKMATINFFDYRVDVEPPI
                     RSEVANIVFAGNLVKSKFLKKLPQLEIFKWHVYGSGMTAEQFPESVVFHGAIDSGVLPS
                     KLVDGWGLVWDGISTDRISGVSGDYLRLNSPHKASLYLASGLPLIVWRESALANVVLQL
                     GLGIAVDNLMEIEPVIKSLSHTQIEKIQTNVQIISQKIRNGGMLKDALESLPVGFDA"
     gene            9878..10945
                     /gene="welF"
     CDS             9878..10945
                     /codon_start=1
                     /gene="welF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 80; E-value:
                     3.2e-24)"
                     /gene_kind="biosynthetic-additional"
                     /note="putative glycosyltransferase"
                     /product="WelF"
                     /protein_id="ACN94855.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.2e-20,
                     bitscore: 61.4, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYLESDFGARCTIVTSPEKLKEKRLDVVHIFNMQPQTIDSSLAY
                     AEMAKALGMKIALSPIYWRLDESFINGALARKGIIDAPKVVVKLATFVSKLLFRDILKK
                     KNFFSRELFLKADKLLQYSDIVLPNSPEEESILKKTFPNATTSNKKWGVIPNAVDAKKF
                     FKVNEQPKQLPDNLKILERLSGKYVLCVARVEQLKNQLRILKALNNHPEIPIVLVGSTK
                     GDSRYVESVKSYAKKRGNTYFIGEVSQQDMAFVYSNAAVHILPSFQESAGLATIEALFC
                     EIPVVTSTEYFCPINFYRFNEFGFQCNPYRLSSVKKAILSAMQNKKDHVGKDYRSFFSY
                     KNAANSTYKAYSTIV"
     gene            11494..12162
                     /gene="welE"
     CDS             11494..12162
                     /codon_start=1
                     /gene="welE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 246.4; E-value: 1e-74)"
                     /gene_kind="biosynthetic-additional"
                     /note="galactophosphotransferase; similar to priming
                     glycosyltransferase; catalyzes the first step in EPS
                     repeating unit biosynthesis in various Gram-positive and
                     Gram-negative bacteria"
                     /product="WelE"
                     /protein_id="ACN94856.1"
                     /sec_met_domain="Bac_transf (E-value: 8e-61, bitscore:
                     194.7, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTTHNENEISNIRKQASLIYLFEKRSFDIFCGLAGLVLVAAVSL
                     VLLPFYSYGRNKGPLFFKQTRVGRHGDRFKIYKFRSMVVDAEGVLHRDSALYKKYVANN
                     YKLPVGEDPRITRLGAFIRKSSLDELPQFINILKGDMSMVGPRPVIEDELAEYGDHVNE
                     LLEAKPGAMGLWQASGRSNIGYPERADLELYYIRHRSFHYDLIILFKNIASIFKAEGAF
                     "
     gene            12760..>12990
                     /gene="rmlA"
                     /note="dTDP-glucose pyrophosphorylase; disrupted by ISLrh2"
     mobile_element  12991..14643
                     /mobile_element_type="insertion sequence:ISLrh2"
     CDS             13056..14552
                     /codon_start=1
                     /note="transposase domain"
                     /product="hypothetical protein"
                     /protein_id="ACN94857.1"
                     /transl_table=11
                     /translation="MQPLFARNAYALGFTLALIADLSEELIMVYRQKATQLSLESFGSA
                     LGTPLSPDNEWVQYAELIPWAKLEEAYQLQFPSKTGRAAKPFRLLYGATLIKLKKGLTD
                     RQVVDDIRDTPAYQYFIGLPEYRAKKPFEHTTLVHFRQRLSAISDLIRNITNDFTRERL
                     EADLPEGTHVLISDATAVPVKIKYPQDTTLLNQSRLNLEQMVTDLAHGLGVEIPRTYRR
                     EAKGKWTAFSRKPRRQNKERRKQLQAQLQYIRRDLRYVAELLAQGGQLTDWQAQRLEVI
                     KQVYEQQLFMFENHTHHVENRIVSLQQPYIRPIVRGKAKQSVEFGAKIDCSMLDGVIDV
                     ERFDFNSFNESTDLEVTLDHAFDLVGEYPDEVLVDTLYRTRDNINLCKKLGIKLNGPKL
                     GRKPKHVDPKQRKADVSAENRRGAIERKFAFLKGSLGLDLVNTRTAESLVVTVDSAIAL
                     ANIDLLLKLFSVPISIVVEQGGLHYQINYKVTEIRPETAA"
     gene            <14644..15213
                     /gene="rmlA"
                     /note="dTDP-glucose pyrophosphorylase; disrupted by ISLrh2"
     gene            15200..15799
                     /gene="rmlC"
     CDS             15200..15799
                     /EC_number="5.1.3.13"
                     /codon_start=1
                     /gene="rmlC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to dTDP-4-dehydrorhamnose-3,5-epimerase"
                     /product="RmlC"
                     /protein_id="ACN94858.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 1.1e-71,
                     bitscore: 230.1, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKPRRQRHLSLKVIPTKLKDVKLVETDVFGDNRGFFTETYTREK
                     FIEAGIKNDFNQDNQSLSAEAGVLRGMHYQMAPYAQTKLVRVVTGVVEDVLVDIRKGSP
                     TYGQWEGYILSQYNHRQLLVPKGFAHGFITLTPNVNFVYKVEGYYAPEADRGIAFDDPD
                     IGIDWPMSKAHLIMSEKDQHHPQLKDAENNFIYGEI"
     gene            15802..16827
                     /gene="rmlB"
     CDS             15802..16827
                     /EC_number="4.2.1.46"
                     /NRPS_PKS="Domain: NAD_binding_4 (4-189). E-value: 4.7e-20.
                     Score: 63.5. Matches aSDomain:
                     nrpspksdomains_rmlB_NAD_binding_4.1"
                     /codon_start=1
                     /gene="rmlB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     256.2; E-value: 7.8e-78)"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to dTDP-D-glucose-4,6-dehydratase"
                     /product="RmlB"
                     /protein_id="ACN94859.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.4e-20, bitscore:
                     63.5, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3.2e-16,
                     bitscore: 49.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 9.6e-15, bitscore:
                     44.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLMITGGAGFIGSNFVHFVYQHHPDVQIMVLDKLTYAGNKANIE
                     DVLGDRVKLVVGDIADKELVDQLMGQVDTVVNFAAESHNDNSLINPDPFLHSNVIGTYT
                     LLEAARKYDVRFHHISTDEVYGDLPLREDLPGHGEGPGEKFTINSRYNPSSPYSSTKAA
                     SDMLVHAWARSFGVRATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLYGTGKNVRD
                     WIHTNDHSSAIWDILTKGKIGETYLIGANGEQDNKTVLELILKLMGKPTDYYDQVKDRP
                     GHDMRYAIDASKTREELGWKPQYTDFEEGLADTIKWYTDHRSWWQDEKSAVEAKYKKNS
                     Q"
     aSDomain        15814..16368
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_rmlB_NAD_binding_4.1"
                     /evalue="4.70E-20"
                     /label="rmlB_NAD_binding_4.1"
                     /locus_tag="rmlB"
                     /protein_end="189"
                     /protein_start="4"
                     /score="63.5"
                     /tool="antismash"
                     /translation="ITGGAGFIGSNFVHFVYQHHPDVQIMVLDKLTYAGNKANIEDVLG
                     DRVKLVVGDIADKELVDQLMGQVDTVVNFAAESHNDNSLINPDPFLHSNVIGTYTLLEA
                     ARKYDVRFHHISTDEVYGDLPLREDLPGHGEGPGEKFTINSRYNPSSPYSSTKAASDML
                     VHAWARSFGVRATISNCSNNYG"
     gene            complement(16926..17819)
                     /gene="wzr"
     CDS             complement(16926..17819)
                     /codon_start=1
                     /gene="wzr"
                     /note="similar to putative transcriptional regulator of
                     polysaccharide biosynthesis"
                     /product="Wzr"
                     /protein_id="ACN94860.1"
                     /transl_table=11
                     /translation="MKKILVRVLLVVLVAALGFGGFVYYMVHNSTSQIYSYNKKTNKSS
                     DDKTTSKKPVAYLLLGTDTGELGRSYKGRTDTMIVMVLNPKSKTTTMVSVPRDTKVDFD
                     DVTIKINAAYSYGSSDTAMEAVEKLLNIKLDGYLLVNMKGLEQMVDAVGGVTVTSPLSF
                     DYEGKSFVKGQSYNLSGSDALKFSRMRYDDPQGDYGRQMRQQLILTSVIGKLKKNPTTV
                     LSQSFLDAVGKNVRTDVSLGSVKNLAMDYRDAGNTIKSDQLHGTGQNIDGQDYEVMSDS
                     ELTRVHDVIQNALNAK"
     gene            17974..18741
                     /gene="wzb"
     CDS             17974..18741
                     /codon_start=1
                     /gene="wzb"
                     /note="phosphotyrosine protein phosphatase"
                     /product="Wzb"
                     /protein_id="ABV54212.1"
                     /transl_table=11
                     /translation="MMIDVHCHMLPGIDDGSKDLTTSLELAQAAVADGITHALMTPHHM
                     NGRYTNHAADVIRMTDEFQDELDRRNIPLTVFPCQEVRINGQLLEAIDHNDILTCDVSG
                     HYVLIEFPSDDVPLYTQNMLFEVMQRGMIPVIVHPERNTRLMKHPGLLYQMVERGAFAQ
                     VTASSYVGTFGKKVQQFSEDIIDAGLAHVFASDAHHLPGRSYEMSAAFKRLTRKRGEKK
                     ARIFEENARALVNGDPLVRFNERKVEKRLLSRY"
ORIGIN
        1 ttaatgaacg agcaaattga ccttgcacag ttgtggaatg tgttcaaacg cagcttctta
       61 gctatgattg tttttggaat cataggaatg gcagctgctt attttggtgc gaaggctttt
      121 attgcaccta agtatgaatc agatacatca ttgttggtta atcgaaagca agacaacgat
      181 ccgaacatgc agttgaatgc acaacaagct gatattcaga ttattaatac atataaggat
      241 atcatcacac gtcccgttgt tttgcaagcg gtggcggaag atcttaccag tccgcagcga
      301 gtgatggtca agaaagcaaa acctgctgtt tatggaacac gatacaatgc cgctacagga
      361 acacgcgaaa ggtacgtcac agaggaagca caacctgcaa aatataaact caaacccgcc
      421 aaatattcca atatttcgga agaggatttg acgaagatgg tttcggtctc gacacaacag
      481 aattcgcagg tttttactgt aaatgttaaa gataccagtc cagttcgcgc aagagatatt
      541 gcaaacgaaa tcgctaaggt gtttgagaaa aaaattgcta aaatcatgag tatctcaaat
      601 gtctctgttg tttctagagc aacggctaat acaattccgg tatctcctaa attaaaattg
      661 ttgagtattg ttgggctggc tttaggcatc ttaatcgcgt taagctgggg gcttgtacgt
      721 gaattgactg accaaaccat taaagatatt gattttatta ctgatgactt agggctggtt
      781 aacctaggaa ttgttaatta tgttgtgcgc atgaaagata tggatcaggc aatacaacaa
      841 agtcgagcaa cggattcagg aaatgatgtg caagacgatc ttgatggaat agattttcca
      901 caacgtagtc gtcgtcgaat ttgaggggga ataaatgatg cagttatcat tttctaaact
      961 ttttcatcgt catcaggagg atcaagaaac ccaaaagaat ggcgttatgc tagtcgcttt
     1021 tgctgagccc aaacatgtag tgtctgaaca gtttcgaacg gtgcgcacta atattgaatt
     1081 tgctggggct gctttagatc gttgccaagt agtcatgttt acgtcttcgg ccatgtctga
     1141 aggtaaatca acggtctcgg ctaatgtcgc ggttacttgg gcccaagctg ggaaaaaagt
     1201 tttgctgatt gatgcggatc tcaggagacc gactattcac gccacgttta ggacattgaa
     1261 tatagacggg gtaacaacaa ttctaattgg aaaagatgaa gctggagctg ttgtagaaga
     1321 aacatttgtt gataatttga gtgtcattac gtcaggacct attccgccaa atccctctga
     1381 attgttaaat tctaaaagaa tggcaaattt actgaattgg gccagggaaa actatgacat
     1441 tatcgttctt gataccccac ctgttttagc cgtatctgat gtacaagtct tggttccaaa
     1501 aactgacggt gtagttgttg tggctaatat gggcaagact ctaaaaggtg atcttcgacg
     1561 aacggttgaa gttttaaagc ttgctaatgc taaaattctt ggctcagttg aacgagttaa
     1621 agctaaacac ggcgatcgag ggtatggcta cggctacggt tatgggtatg gtacgaatac
     1681 tggaaagaag taacccatca tatcaagttt agacaataac atacttgtct taggggatac
     1741 acatggaaac aaacaattta gaagattcgt ttcaaccgtt cttggttaaa acgtatttgt
     1801 ttatttattt ttggctcgtc atcatctttg gcttcacagc cgagtcgatg atcagtccag
     1861 ttgatcaacc atctgcttat ccgagttttg tttcttttgg caacaaaaca gcgtatttcc
     1921 ttgcgtcatt actcctagtg ttaggttttc ttaaaagacg ttctctctta aattggctta
     1981 taactgggcc tctctttctg gttatcgttt atggttatct gtttgttaat caacaagttg
     2041 cagttgttgc gtttatattt ctggtttgga gttctcaaac agtttccttt agaagtctgg
     2101 tgaggataga tctttttgct aggattattg ttacaatttc actcttcgtt gtgaataatc
     2161 tacaattact cccggttagt ccgattattc aactcggagt atacagtaga ttctcttttg
     2221 gatttcatca ccctaatgct ttagggatgt acttaatgat gatctctctt gaaatgtttt
     2281 atttgtacgc aaggaaaagc gttaagccta ttgttttgct gattctgagc ggaattctta
     2341 tttttgtcct tactcgctcg cgtggttcgc taatttcagt gatgagtttt gtggtattgg
     2401 ttacggtttt taatactttt aaaagcataa gttttcgaaa actgttatat agtttttgca
     2461 tacttgtccc gttaatctgt tttctgggtt cattaacaat ttccatattt cttccatcta
     2521 gttcaaaggt ctttcaaact ttaaatgaat ggatgtctgg gcgtccagaa ctgcttaagc
     2581 ttgtttatga ttattacgcg caaaaaagtt tcttcggcgg cgatattgca gagttggcta
     2641 acgcatttta ttcatggtct attaatgtta gatatctata cgttgataat cagtatatgt
     2701 attcggttat gatatttggc tggtttggtg cagttctaga agttctttat tcgacttact
     2761 gtggcattcg cgcaaagatt tttggcgatt cctatctttt gttttggctc actgcaatag
     2821 ctctttttgg gttagttgaa acaaagttag tcacccttga tatggcactt ccttttatgt
     2881 gcttaggaag cttgacagaa ggtgtcacca aagacaaaaa ggttttgtct gctgaacaag
     2941 gtcacctaca ggccaaagct aattagtaat acattttgtt aatctggagc ataatttgat
     3001 atgggggtat taaaatgaaa ttattagttg ttggggctgg cttatttgga gcgacagtag
     3061 ctcatgagcg tgcactaaaa ggggatcaag tcgatgtcat tgaaaaacgt agtcatttag
     3121 ccggaaatat ttttactgaa gaagttgaag gtattcaggt tcatcgatac ggagcacata
     3181 tttttcacac gagtaataaa aaaatctggg agtatattaa ccagttttca tcatttaata
     3241 gatatacaaa cgaagttatt gccaactaca aaggtgaaat atataattta ccttttaata
     3301 tgaatacctt taataagatg tggggagtta tcactcccgc tcaagccaaa gcagagatag
     3361 ataaacaacg ggcttccatg gcgggaaagg ttccacagaa tcttgaagaa caagcaatat
     3421 ctcttgttgg taaggatatt tatgaaaagc taattagaga ctacacggct aaacagtggg
     3481 gtagggaacc taaagaacta ccttcattta ttatccgccg acttcctgtt cggtttacgt
     3541 atgacaataa ttattttaat gacctttacc aaggaattcc cgaaggtggg tacactcaga
     3601 ttgttgaaaa aatgttggat catgcaaaca ttaaggttca cctaaacacg gattttctta
     3661 cccataagga agagtattta actcgttatg atcaggtagt atacacgggt atgatcgatc
     3721 aattctttga ttatcagtta ggcgcgctgg aatatcgaag tcttcgtttt gaaactgaag
     3781 tactagacgt tgataattat caaggaaatg ctgtagttaa ttacactgat tccgatacac
     3841 cttttactcg aatcattgaa cataaacatt ttgaatttgg aaaaggaaat caaggtaaga
     3901 cggtcataac gcgtgaattt ccggctgaat ggtctaaggg tgatgagccc tactatcctg
     3961 taaatgacac aaagaacaac catttattta cagaatacag agatcttgcc actaaaaaat
     4021 atccacaggt cgcgtttggt ggccgtttag gactttatcg atattataat atggatcaag
     4081 ttattactgc tgctctacaa tttgtaaaag gaaagttctt tgcacgaatt aagacggaaa
     4141 tttgattctc atgtttctat taaagcaaac tcttaggtaa caggccaatg atcggagagt
     4201 tatatgacag tagtaaagaa ctttttatgg aatatggggt atcaggtttt gtcttgctat
     4261 taccgatcat tacaattccc tatgtttcac gtgtgcttgg accaactgga attggtatca
     4321 acgcgtatac taattctgtt gtgcagtatt tcattctatt tggcactttg ggtatcaccg
     4381 tttatggtaa tcgtgaagtt gcatatgaaa gagatgaccc tcaaaaatta tcgaacgttt
     4441 tttgggagtt aactttttta aaatttttga caacgggcgt cgccgttatc gcgtatctta
     4501 cctttatatt tttgtctaaa cagtaccgtg ttttctacct gattcagggt tcactgttgt
     4561 tagcttcagc gattgacgtt tcgtggtttt ttcagggttt ggaagaattt agaattacag
     4621 tggtacgaaa tacatttgta aaaattattt cacttgtttt gatttttaca ttagttagaa
     4681 caaagaatga cttatggatt tatgttttga ttttgggcgg atcacagtta attggtaatt
     4741 taacgctgat tccttatctt actagatatg taaagtggcc agtcttgaga aaaatgagac
     4801 ttggccgaca cttgaagcct acaattggga tgtttattcc acaaattgct tcacagatat
     4861 atttgcaagt gaataagact atgctgggag catacatcgg ggtcgaagct gcaggttatt
     4921 atgacaactc agataaaatt ataaaaatat tgttagccat cgtcacagct acaggaacgg
     4981 ttttgttgcc acatgtggcg catagttttg ctagggggga tcgtaaggct gttttttcct
     5041 cccttagtaa gtccatgcat tttatattgt tgttagcttt tcctatgtca gctggactcg
     5101 cttcgatatc tcctgttttc acaaatgttt ttttcggaat caagttcagt gcagttgctg
     5161 tactactagc aatagagtca cttgttatta ttttggttgg aattagtaat gccatcggta
     5221 tacaatatct actgccgaca aatcaaacta ggccttttac ggtttccgtt gcattaggtg
     5281 caattgtaaa catttttttg aatattccta tgattttact ttggggaacg gtcggtgcca
     5341 tgacggcaac cgttatttca gaagctgctg ttactgcata tcaacttgtt tatgtaagaa
     5401 aacagatgga tatttctcta ctttttacgg aaacctggaa gtacttactt tctgctagtt
     5461 tgatgggtgc atatattttt tggtatatgc attttatgcc gtttggaaat atggttaaac
     5521 tagtaacaac cattttgcta gggacgatca tttatatttt gatcttatta cttttaaagc
     5581 cgcgtcactt gattgaaatg gtgtctagta ttagacaaag ataatctttt ttggctcaga
     5641 gaggggtggg gaacttgctg attaaaatta ttatagctgc tcataaacct gttcaggtac
     5701 caaatgacca aacttatttc cctgtttatg ttgggagcaa atttcatgaa tcgacgccca
     5761 agggttttct aagagatgat tcagggaaaa atatttcatg gaaaaacccg cattataatg
     5821 aattaactgc gatttattgg gctaagtaca atcttgattt tgatatcctt gggcttgtgc
     5881 attatcgcag attttttgtg aataaaaaga agttcggaag tcgctcttat gacttaatta
     5941 agcagtctga cataaaaaaa ttaatggctc atacagatgt tgtggttcca aaaaaacggc
     6001 actattacat tgagactata gaatcacact tttatcactc ccacgatcgt caaggacttg
     6061 actgtttaaa gaaggtgatg gaagaacaac ctgaggccta tagattcgcg tttagaaagg
     6121 ttttaaatgc cagatcagcc catatgttta acatgtttat tatgaagaaa aaagtcttcc
     6181 aagattatac gaattggtta ttttcaattc ttgatcaagt tgatgaactt ttagatttca
     6241 aatagtctag aaggcaatga aactagagtt gatgggttcc ttgcagaatt tttgttggat
     6301 gtctggctaa aggcaaatga agttccttat acagagtgcg attacaagtt tacagaaaac
     6361 caacattgga tcagaaaaat ctatggtttt cttttcaata agtttaacag acgtaagttc
     6421 gtaactacgc atatttccaa taataggaaa taaataagga gggtctggaa actatgataa
     6481 gaactttagt tgttgcagac ttcttgccgg ctagtggggt tacgactttc gttgaaaatg
     6541 cctttttaaa acagcgccaa gggttcagtt tttcagcact tgcaattgct ggggatgaaa
     6601 gtaacaaatt acattttgaa aaagcaggat ggacttttac cgatatttct ccggctaaca
     6661 agaactatat tcgacatata aaagactggt taaaatttgc aagaagaaat aagcatgctt
     6721 ttgatattgt ttattttaat tattctgcaa gttggaatat actgccgatt tttttctgta
     6781 aatttataat gcatgcgaaa attgttgtcc atggtcataa tacgtatttt ggtacagaaa
     6841 tacatggggt gaagaagttt gcgttgacag tatttcacct tattggcaaa cagatagccg
     6901 ctacatttct aatcgactct tttgtagctg tttctaatga agcagctaag tggatgtttc
     6961 ctagtcgaat tctcagaaaa aatcgagtcg aagttatacc gaatggcatt gacttatcag
     7021 actatacttt taagcgcgcc actagagtaa aagttcgaga agcattagat gttcaaaata
     7081 aaattgttta tgctacaatc ggtgttctgg aaatgagaaa aaatattagc tttgctctag
     7141 acatatttgc agcgataatt cggcgtaatc caaactcagt attgttagtg attggcgatg
     7201 gaacacagag ggaaatgttg aaacaaaaag ctagacgtct tgaattgggt gatagtgttc
     7261 gatttttggg gagaagaaaa gacctcgcac agctgtataa tgcaattgat gttttactct
     7321 ttccttcgtt gaatgaaggg ttgagcttta cgctcataga agctcaggca aatagtttac
     7381 cagtttatgt ttcggataga gtcccgctag gtaactattt accgaatttg gttcatgttg
     7441 taaaactcag cgaatcatcg gattcctgga gcaaaaggat tactgcaact gaaaaacatg
     7501 tgcgagttga tgaatcgaag cgaatgaaaa aaatcggata tgatcaatta gatatgcgcg
     7561 aacatgttct tcacctgttg gaagccttac agggagggaa tacagaatga cttttgacca
     7621 tcttgtgatt ttgatgtcaa catataatgg tgagaggttt ctaaaacaac aactggactc
     7681 aattgttcag caggattatg agaactggga tcttataatt cgggatgatg gttctacgga
     7741 tagcacacag cagattatag atgattatgt tctaaaagat aaccgaattc attcttttcc
     7801 cgattcagca ggtaatcgtg gccctgccaa ttctttctta atgatgttga cctccatcag
     7861 cgccccattg tttatgtttg ctgatcaaga cgatatttgg taccccaata aggtaggtct
     7921 aacggttggc tcatatatgc agcaaacatc gagtgcttca gtaccaacgc tcgtatttac
     7981 taatatggat acaattgacg catctggtac tttgattcaa tcgaatattg ttcctgaaaa
     8041 tgcaagggtt tctgtcaaca ccatcttagt tacaaatatt gtgaccggtt gtacagttct
     8101 aatcaacaaa agtttagctg atagaataag gttgtctgat actcgctcaa ttgtgatgca
     8161 tgactggtgg atggctatga tagcagcatt tttaggtaat gtagtgtatc ttccaacagc
     8221 cacgattgga taccgtcagc atggggataa cgctgttggg gtaaatcatt cattcaggtc
     8281 aagaattaat aaagctttaa actatagtaa tcagaggaag cttttttcaa agcaaatggc
     8341 acaaataaaa ttacttgata caagatttgg taaaaatttg tctgtgagcc gtaaagtaga
     8401 attggattct ttgatttcta ttcaacgatc caagagattt ttgtcaaagt ttagttggtt
     8461 attaagacat cgggcaaaaa agacctcatt ggttggaact ctatcgtttt attatttatt
     8521 tttaacaaca aatgttgaat aattgatatt ataaatgttg ttatcagaga gtatttcgac
     8581 gttttttgaa agtgggaaaa tcatgattga atttgacggg tacaatagca aaagtttcga
     8641 tgcaggcttt aaagcacgag ccgatgtcaa atacttctcc aataggatgg gaattaaaac
     8701 tgcagagata cctgcaacaa gagtaaattt aaagataaac agggaacttc aacgactacg
     8761 agcagttcgt agtctttcaa agaaattgtc ggcagaccaa tcagttctta tccaatatcc
     8821 gttacctttt aattcttttg attatagcct gttacataaa acactcttaa agcataatgc
     8881 aaagtgtatt tttcttgttc atgacctcat ttctgttcaa ggacaggcta aaaatgtatc
     8941 aattaaacag gaaatcgaag aattaaaaag ggctgacttt ttgattgtcc ataatcaagc
     9001 aatgcaaaat tttcttgaag atcaaggcct ttctcagaag atggctacta ttaatttttt
     9061 tgattatcga gttgatgttg aaccgcctat tagaagcgaa gtcgcaaata tagtttttgc
     9121 tggcaattta gtaaagtcaa agtttttaaa gaagcttccc cagttggaaa tttttaagtg
     9181 gcatgtttat ggttcgggta tgacggcgga gcaattccca gaatcggtcg tttttcacgg
     9241 tgctattgac tctggcgtat taccatccaa gcttgttgat ggctgggggt tggtctggga
     9301 tggaatctcg actgatcgta tcagtggggt ttcgggagat tatctccgct taaactcgcc
     9361 gcacaaggca tcactgtact tagcttctgg attacccttg attgtttggc gagaatcagc
     9421 tttagccaat gttgttctgc aactagggtt aggaatcgca gttgataatc tgatggaaat
     9481 tgaacctgtc attaagtcac tttcacatac acagatagaa aaaattcaaa cgaatgttca
     9541 aatcatctcc caaaaaattc gtaatggtgg tatgttgaag gatgcgttgg aaagtctacc
     9601 ggttggtttt gacgcataga aatttcaaaa tggttcgatc atcttgtaag aaatattcaa
     9661 caactattcc agacgtgctt tagagatcaa gaatgtcatc agaattaatg cttgcgccta
     9721 aggcccacct gaaatgatga tctaaattcg aaaaaatata attgtcgagt aactaaatca
     9781 attttaagga gacagcaatt tatggatatc ggatttgcgg ttcgatcgga ttttctcaca
     9841 cgaaaaaggc ggtgatagtg ttcaactgtt gaacactatg aaatatcttg agtcagactt
     9901 tggggcgcgt tgtactattg ttacatctcc tgagaagctg aaagagaaac gtttagatgt
     9961 tgtgcatata tttaacatgc aaccgcagac tatagattca agtcttgcat atgctgaaat
    10021 ggccaaagct ctcggcatga agattgcatt atcaccaata tactggaggc tggatgaatc
    10081 atttattaat ggtgctttag caaggaaagg tataattgat gcgccaaaag tagtagttaa
    10141 gttggcaacg tttgtgtcaa aactattgtt tagggatatt ttaaaaaaga agaatttctt
    10201 ttcgcgagag ttatttctaa aggctgataa gttgttacag tattcagata ttgttttgcc
    10261 caattcaccc gaagaagaat ccattctcaa gaagaccttt ccaaatgcga ccacaagtaa
    10321 caaaaaatgg ggagttattc ctaatgcagt agatgcaaag aagtttttta aagtcaatga
    10381 acaacctaaa cagcttcctg acaatttaaa aattctggaa agactttctg gtaagtatgt
    10441 cctttgtgtt gcaagagttg agcaactcaa gaatcaattg cggattttga aggcattaaa
    10501 caatcatcca gaaattccaa ttgttttggt tggatccacc aagggtgata gccggtatgt
    10561 cgaaagtgtt aaatcttacg caaaaaaacg cggaaacaca tactttattg gtgaagtttc
    10621 acagcaagat atggcatttg tttattcaaa tgctgcagtg catattctgc cttccttcca
    10681 agaatcagct gggttggcga ccattgaagc tcttttttgc gaaattcctg ttgttacatc
    10741 aacagagtat ttttgcccaa taaattttta tagattcaat gaatttggtt ttcagtgtaa
    10801 tccgtataga ctttcctctg tcaaaaaggc aattttatca gctatgcaaa ataaaaaaga
    10861 tcatgttggc aaagattatc gttctttttt tagctataag aacgctgcca actctaccta
    10921 caaagcttac tctacaatcg tgtaacgaca attaaaatag ttttaattct tttcatgctt
    10981 ttgtgtagga gttgcaaagg cggtcttgat tgaaggagac aaaattaacc tgctgctatt
    11041 attttaaaat aaatcatata caaaggttat atattttcat ctacctttga cttttaatta
    11101 aaattggtac acaaagaagt tcaagatgag atctgaatcg ccgaccatgg gagcaaaatt
    11161 aatgctaata tcgatgtttc ttggtctcac caaggttaga ccagtttaga atattaacta
    11221 tgcgaatagc gacatagtca ttctcgtctt caatccgaga gtctcttttt agcatgaata
    11281 gggtggctta gatgcgggtc ctggcatctt aacgggtggc ttgcataggc cggattgaca
    11341 aactaatttc attgtattgg tctagctcga atggtattga acgtttaact ttagatttga
    11401 cgttttcttg tacaatgcca aaaaatgtta taaaatcaaa taaattggcg cttggggtag
    11461 cgtttgggga ggaatttaaa tttggaaaaa cagatgttga cgacgcataa tgaaaacgaa
    11521 atatctaata ttcggaaaca agcttcactg atttacttat ttgaaaaaag aagcttcgat
    11581 attttttgtg gattggctgg tctagtttta gttgccgcag ttagcttagt cttacttccg
    11641 ttttattcgt atgggcgaaa taagggaccc ctttttttca aacaaacgcg cgttggacga
    11701 cacggggata gattcaaaat ttataagttt cgaagtatgg ttgtcgatgc tgaaggggta
    11761 ctgcatcggg attctgcgct ttataagaag tatgtagcaa ataattacaa attaccggtt
    11821 ggtgaggatc cacgtattac gaggttgggg gcttttattc gaaagagttc acttgacgag
    11881 ttaccccagt ttattaacat ccttaaaggt gatatgagta tggttggccc gcgcccggtc
    11941 attgaagacg agttagctga gtatggcgat catgttaatg aactacttga ggcaaagcct
    12001 ggtgcgatgg gattatggca agctagtggt cgaagtaaca ttggttatcc agaacgtgca
    12061 gacttagagc tatattatat tcgacacaga tctttccact atgatctcat tattttgttt
    12121 aaaaatattg cttctatctt taaggctgag ggggcttttt aactatcatc gtgtagcata
    12181 gaagttttaa tctgcctttt tgacatagta aggtccatct aaaacggttt cgatattctt
    12241 tatgctgtag gaatatcgaa gccgttgttt tttgaggctg ctttttcgca attagtttgc
    12301 ctgaatcctc atcgaaccta gtaaaaaaac cagtaatgcc ttgtcatcgc tgtgggcgga
    12361 aaaagcgggt gattcagtag atcagtagta ttgaatatac ttgcggaaat taagtccgtt
    12421 gatctagggt aaaggcatga agcttaaaat aatcacgctt gaatgcacac ttgatcgcat
    12481 tgcctaattt gaatttcgga aaagaaggag ctctttcaac caataaaaag actttcacag
    12541 ttaattgatc ttgcctgaaa ttcctgaatt tacaacgtct aagtattaac ttgaaaagtt
    12601 gttaaaagtg gatctcgtga actaataaat taacaaacta atatacaatt ctataaaaag
    12661 caacacaatt taaagttcta ctggtaaaat gcttagtgtt agggtttgct taaactttag
    12721 aaacactaca tactaaacta cgcgagggga gaaaatgcaa tgaaaggaat tatcttagct
    12781 gggggctctg gtacaagatt gtatccaatt acagaagctg tttctaagca actggtaccg
    12841 gtctatgaca agccaatgat ctactatccc ctgtcaacca tgatgttggc cgggattcgc
    12901 gatatcttgg tgatttcaac accaagggat attgatcgtt ttcaggatct gttaaaagac
    12961 ggtaaacaac tgggactcaa tattagttag tggatggtga aaaactataa aagtacttta
    13021 ataataggat ttaccaatag ttcggcgtat aataagtgca acccttattt gcccgaaatg
    13081 cctatgcttt gggatttacc cttgcactta tcgctgacct atcggaggaa ttgatcatgg
    13141 tttatcgtca aaaagcaacg caactgtcac ttgaatcctt tggaagcgct ctgggaacac
    13201 cgctcagccc ggacaacgag tgggttcaat atgcagaatt gatcccatgg gccaaacttg
    13261 aagaggcata ccaattacag tttccttcaa aaaccggccg agcagcgaag ccatttcgat
    13321 tgctttatgg cgcaacgttg atcaagttga agaaaggcct gaccgaccgc caagttgtcg
    13381 acgatatccg tgatacacca gcctatcagt acttcatcgg gttacccgaa tatcgcgcta
    13441 agaagccatt tgaacacaca acgttggtgc actttcgcca acggctttca gccatctcag
    13501 atttgatccg caacattact aatgacttca cgcgcgagcg gttggaggcc gatctacctg
    13561 aggggacgca tgttttgatt agtgatgcga ctgccgttcc ggtcaagatc aagtatcccc
    13621 aagatacaac gctgcttaac cagagtcgtt tgaatctcga acaaatggtc acagatctgg
    13681 cccacgggtt aggtgtggaa attccgcgga catacagacg tgaagcaaaa ggtaagtgga
    13741 ccgctttttc gaggaaaccg cggcgtcaaa acaaggaacg ccgcaaacag cttcaagctc
    13801 agctacaata catccgaaga gatctgcgat atgtggcgga actgcttgcg caaggcggtc
    13861 agctcactga ttggcaagca cagcgtctgg aagtgattaa acaagtctat gagcagcagc
    13921 tcttcatgtt tgagaaccac actcaccatg tcgagaatcg catcgttagc cttcaacagc
    13981 cgtatatccg gccaatcgtg cgaggtaagg caaagcagtc cgttgagttt ggcgccaaga
    14041 ttgactgttc catgttggat ggcgtgattg atgtagagcg tttcgacttc aattcattta
    14101 acgaaagcac tgatcttgaa gtaacgcttg accatgcttt tgacctagtg ggtgaatatc
    14161 cggatgaggt gctggtcgat actctctatc gcacgcgaga taacatcaat ctgtgtaaga
    14221 agctaggcat taaacttaat gggccaaagc tgggtcgaaa gcccaaacat gtggatccga
    14281 aacagcgcaa agccgatgtc agtgcggaaa atcgtcgggg tgccattgag cgcaagtttg
    14341 ccttcttgaa aggttcactt gggcttgact tagtgaacac cagaacggct gagtccttgg
    14401 tggtaacggt ggatagcgcg attgcattgg caaatatcga cctcctcctt aagctttttt
    14461 ctgtaccaat ttctattgtg gtcgaacagg gtggcctgca ttatcaaatc aactataaag
    14521 tgactgaaat tcggccagaa accgcagcct aaatcaccag gcactagtta caaagtacag
    14581 gaaaagccaa atggcctggc ggaagctttc attgtcgggg ctgacttcat tggcgatgat
    14641 tccgtgtgct tgattctcgg tgacaatatc ttttatggca gcggcttgtc caagctggtt
    14701 caacgctcgg cggctaaaac gaccggggca acggtgttcg gctatcaagt caacgatcct
    14761 gaacgttttg gggtagtcgc ttttgatgag cagcatcatg tgcaatcgat tgtcgaaaag
    14821 ccagagcatc cggagagtaa ctttgcggtt accggcatgt atttctatga caaccaagtg
    14881 gtggacattg ctaagaatct caaaccgtca ccacgaggcg aactagagat tacggatgtg
    14941 aacaaagcgt atctcgaacg tggccaactt gacgttgagc ttttgggtcg aggatttgct
    15001 tggttagata ctggcactca tgaatcctta catgaggcgg ctagttttat tgagaccgtt
    15061 cagaagcgac agaatcttaa aattgcctgt ctggaagaag tagcctaccg aatgggttac
    15121 attgatcgcg atcaattacg cgaactcgcg cagccactta agaagaacga ttacggccag
    15181 tacattttgc gcttggcaga tgaagaagcc taggaggcaa agacacttga gtttaaaagt
    15241 tattccaacc aaattaaagg acgttaagtt agttgaaacc gatgtattcg gcgacaatcg
    15301 cggctttttc acagagacgt atacccggga aaagttcatc gaagccggaa tcaaaaacga
    15361 tttcaaccaa gacaatcaat cactgtcggc cgaagccggg gtcttacgcg ggatgcatta
    15421 tcaaatggcg ccttatgcgc agacgaagct ggtgcgcgtg gtgactgggg tcgttgagga
    15481 tgttttggtg gatattcgca aaggctcgcc aacatatgga caatgggaag gttatatttt
    15541 gagccaatat aatcatcgcc aactcttggt tcctaaggga tttgcgcatg gcttcattac
    15601 cttaacgccg aacgttaact ttgtttataa agtggaaggt tattatgccc ctgaagctga
    15661 tcgtgggatt gcctttgatg acccagatat tgggattgac tggccgatgt caaaggcaca
    15721 tctgattatg tcggaaaaag atcagcatca tccgcaatta aaagatgccg agaataactt
    15781 tatttacggg gagatttaaa catgaaactt atgattacag gcggggccgg ctttatcggc
    15841 tcaaactttg tccattttgt ttatcagcac catccagatg ttcagatcat ggtcttggat
    15901 aagctgacct atgccggcaa taaagccaat atcgaagacg ttttgggcga tcgggttaag
    15961 ttagtcgttg gcgatattgc ggacaaagaa ctggtcgatc aattgatggg tcaagtggac
    16021 acggtggtta actttgcggc tgaaagtcat aatgataact cactgattaa tccggatccg
    16081 ttcttacaca gtaacgtgat tggcacctat actttgttgg aagcggcccg taagtatgat
    16141 gttcgcttcc accacatctc aaccgatgaa gtttatggtg atttaccgtt acgtgaagat
    16201 cttcctggcc atggtgaagg acccggtgaa aagttcacga tcaacagtcg ctacaacccg
    16261 tcaagccctt attcttcaac caaagcggcc agtgacatgc ttgttcatgc atgggcacgt
    16321 tcctttggcg ttcgggcgac catctctaat tgctccaata actatggccc ctatcaacat
    16381 attgaaaaat tcattccgcg acaaatcacc aatattttga gtggcattaa acctaagctt
    16441 tacggaacgg gtaagaatgt ccgtgactgg attcacacca atgatcattc cagcgccatc
    16501 tgggacattt tgactaaagg caagattggc gaaacttact taatcggggc taatggcgaa
    16561 caggataaca agaccgtgct cgaattgatc ttgaagctca tgggaaaacc gactgactat
    16621 tatgatcagg tcaaagatcg cccaggccat gatatgcgtt atgccattga cgcctccaag
    16681 acccgcgaag agttagggtg gaagccgcaa tataccgact ttgaagaagg cttggcggac
    16741 accattaagt ggtacaccga ccatcgcagt tggtggcaag atgaaaaatc tgcggttgaa
    16801 gcgaagtaca agaagaacag tcaataagtt gaacttaact tcaattaccc gagaaataaa
    16861 ggaaccacca tgaattgatt tgaaatttga tcaattcatg gtggttccat ttattatctg
    16921 ttttcttatt ttgcgttcaa cgcattctga atcacatcat gcacccgagt aagttcagaa
    16981 tcagacataa cttcataatc ttgtccatca atgttctggc ctgtgccatg tagctgatca
    17041 ctcttaatgg tattcccggc atcacgataa tccattgcca ggtttttaac tgatcctagg
    17101 gagacatcgg tacgaacgtt tttaccaaca gcgtctaaga agctttgact caacacagtc
    17161 gttggattct tcttaagctt accgataacc gacgtcaaaa taagctgttg ccgcatctga
    17221 cggccataat ctccttgagg atcgtcatac cgcatccgcg agaacttcaa ggcatcactg
    17281 ccgctcaaat tgtatgactg acctttaaca aatgatttgc cttcatagtc aaagcttaat
    17341 ggcgaggtta ctgtcacgcc accaacggca tctaccatct gttctaggcc tttcatgttg
    17401 acgagcaggt aaccatccaa tttgatgttt aacagcttct caacggcttc catggcggtg
    17461 tcggaggaac cgtaagaata ggctgcgttg attttgattg tgacgtcatc aaaatcgact
    17521 ttggtgtcac gtgggactga gaccatggtg gttgtttttg atttggggtt gagtaccatc
    17581 acgatcatgg tgtcggtacg gcctttgtag gagcggccaa gttcgcctgt gtctgtaccg
    17641 agcagtaagt atgcgaccgg ctttttgctg gtggttttat catcggaaga tttgtttgtc
    17701 ttcttattat aggaatatat ttgcgatgtc gagttgtgaa ccatgtagta cacgaagccg
    17761 ccaaacccca gcgcagcaac gagtacgacg agtagaacgc gtactaggat ctttttcatc
    17821 tttaaacctc atttcctccg taatctttgc atattatacc gcaaagtctg ccagctcgct
    17881 gatctattgt gaaacgttaa caaactgtta caaaaaaatt tgaccttggg agcgcttcat
    17941 tagatactta gatagtattg gaaggggaac tgaatgatga ttgatgtgca ttgccatatg
    18001 ttaccgggaa ttgatgatgg ttcaaaagac ttaaccacgt cgcttgaatt ggcacaggcg
    18061 gcggtggctg atgggattac gcatgcgttg atgacgccgc accatatgaa tggacggtat
    18121 acgaatcatg cggctgacgt gattcggatg acggatgagt ttcaagacga gttagaccgc
    18181 cgcaatattc cactaacggt tttcccgtgt caggaagtgc ggattaacgg tcagttgtta
    18241 gaagcaattg accataacga tattctgact tgtgacgtga gcgggcatta tgtgttaatt
    18301 gaatttccgt ctgacgatgt gccgctttat acccaaaata tgttgtttga agtgatgcag
    18361 cgtggcatga ttccggtcat tgtccatcct gagcggaata cccgactgat gaagcatccc
    18421 ggtttgcttt atcagatggt tgaacgtggg gcctttgcac aggtgacggc tagcagctat
    18481 gtgggcacat ttgggaaaaa ggtacaacaa ttttccgaag acattatcga tgcggggtta
    18541 gcacatgtct ttgcctctga tgcccatcac ttaccgggtc gcagttatga gatgagtgca
    18601 gcgttcaagc ggttgactcg taagcgtggc gaaaagaaag cccgaatttt tgaggaaaat
    18661 gctcgcgcct tggttaatgg ggatccgtta gtccggttta atgagcgtaa ggttgaaaag
    18721 cgtttgttgt cgcggtatta atcaactgag aaacgccttg attgacttag cgtgagaaaa
    18781 aattagcact cgggttgcgt gagtgctaat ttcatgctat aatacattat gtaaacaagg
    18841 aaaaggcgca acagtataag tgccaacaag tgaataagca cgacacgaaa gtactgccag
    18901 agcgcctggg agtgcttttt tgtagagcgt gaacagggcc gcttagaaac cggagtgtaa
    18961 gtggccttgg atgtgctggt cgggttttga ccagtgcatc caaggccctt acacgcaggt
    19021 ttctggccct gcgaacgcgt ttaggaaagc agcaagatct tgtgcatcct aataagctcc
    19081 ccgccaccac cgccttttcc ccgcatattc ccaacaagga ggaattcgac tatggcaaac
    19141 tttaacgatc cgtttttcaa tcatgacatg gacgatgtat tcaatcagat gcttcaagga
    19201 atgggtaaag gcgagtcagc ccgctatgtg gtgaatggcc acgaaatgac gccggatgaa
    19261 tttgcgcagt atcgggcgac tggtcagctg ccaaagcaag gcgatgaaat cccggttgaa
    19321 acgactggcg aacaagcggt taagaaaggc ggtattcttg aaaagcttgg ccgcaacctg
    19381 acgcaagaag ccaaggatgg tctgcttgat ccggtgattg gccgtgatca cgaaattcag
    19441 gaaactgccg aaattttgag tcgacggacg aagaacaatc caattttggt cggtgacgcc
    19501 ggtgtcggca agaccgcggt ggttgaaggc ttggcacaag cgattgtgaa gggcaatgta
    19561 cctgaatcaa ttaaagacaa gcagatttgg tcgattgatc tgtcgaatct ggaagcaggc
    19621 acgcaatatc gtggcagctt tgaagaaaag attcagaatc tgatcaaaga agtgaaagct
    19681 gctggcaatg tgcttctgtt ctttgatgaa atccatcaaa ttcttggcgc cggtgcaact
    19741 ggtggcgaag agtctggcgg taagggcctc gcggatatta tcaagccagc ctttgtc
//
