BGC0000804: acarviostatin I03 biosynthetic gene cluster from Streptomyces coelicoflavus ZG0656
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Location: 14,922 - 55,264 nt. (total: 40,343 nt).
This entry is originally from NCBI GenBank AHGS01000039.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000804
Short description acarviostatin I03 biosynthetic gene cluster from Streptomyces coelicoflavus ZG0656
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • saccharide (None)
Loci
AHGS01000039.1
14922 - 55264
via
Compounds
  • acarviostatin I03
  • acarviostatin II03
  • acarviostatin III03
  • acarviostatin IV03
Species Streptomyces coelicoflavus ZG0656 [taxonomy]
References
Chemical products information
acarviostatin I03 Evidence:
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C37H63N1O28
Chemical database entries
PubCHEM
acarviostatin II03 Evidence:
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C56H94N2O40
Chemical database entries
PubCHEM
acarviostatin III03 Evidence:
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C75H125N3O52
acarviostatin IV03 Evidence:
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C94H156N4O64
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SMCF_976
  • EHN79423.1
  • scatZ2
 14922 - 19781 (-) alpha-amylase ScatZ2
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    • SMCF_977
    • EHN79424.1
    • scatZ1
    		 19778 - 22906 (-) alpha-amylase ScatZ1
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      • SMCF_978
      • EHN79425.1
      • scatE2
      		 23020 - 24717 (-) alpha-amylase ScatE2
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        • SMCF_979
        • EHN79426.1
        • scarC2
        		 25039 - 26106 (-) lacI/galR-like protein ScarC2
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          • SMCF_980
          • EHN79427.1
          • scatE1
          		 26103 - 27764 (-) alpha-glucosidase ScatE1
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            • SMCF_981
            • EHN79428.1
            • scatG
            		 27820 - 28725 (-) ABC transporter membrane protein ScatG
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              • SMCF_982
              • EHN79429.1
              • scatF
              		 28748 - 29755 (-) ABC transporter membrane protein ScatF
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                • SMCF_983
                • EHN79430.1
                • scatH
                		 29869 - 31143 (-) acarbose/maltose-binding protein ScatH
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                  • SMCF_984
                  • EHN79453.1
                  • scarC1
                  		 31548 - 32576 (+) HTH-type malR-like transcriptional regulator ScarC1
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                    • SMCF_985
                    • EHN79431.1
                    • scatB
                    		 32595 - 33572 (-) dTDP-glucose 4,6-dehydratase ScatB
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                      • SMCF_986
                      • EHN79432.1
                      • scatA
                      		 33650 - 34723 (-) dTDP-glucose synthase ScatA
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                        • SMCF_987
                        • EHN79454.1
                        • scatV
                        		 34956 - 36254 (+) dTDP-4-keto-6-deoxy-glucose 4-aminotransferase ScatV
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                          • SMCF_988
                          • EHN79455.1
                          • scatW
                          		 36251 - 37276 (+) ABC transporter ATP-binding protein ScatW
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                            • SMCF_989
                            • EHN79456.1
                            • scatX
                            		 37273 - 38097 (+) ABC transporter permease protein ScatX
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                              • SMCF_990
                              • EHN79457.1
                              • scatY
                              		 38094 - 38900 (+) ABC transporter permease protein ScatY
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                                • SMCF_991
                                • EHN79458.1
                                • scatU
                                		 38907 - 40370 (+) putative kinase (1-epi-valienol-7-phosphate-1-kinase) ScatU
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                                  • SMCF_992
                                  • EHN79459.1
                                  • scatS
                                  		 40390 - 42465 (+) glycosyltransferase ScatS
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                                    • SMCF_993
                                    • EHN79460.1
                                    • scatR
                                    		 42515 - 43579 (+) putative 1-epi-valienol-1,7-bisphosphate-1-adenylyltransferase ScatR
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                                      • SMCF_994
                                      • EHN79461.1
                                      • scatK
                                      		 43576 - 44502 (+) acarbose-7-kinase ScatK
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                                        • SMCF_995
                                        • EHN79462.1
                                        • scatI
                                        		 44520 - 47603 (+) putative glycosyltransferase ScatI
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                                          • SMCF_996
                                          • EHN79463.1
                                          • scatQ
                                          		 47600 - 49708 (+) putative acarbose 4-alpha-glucanotransferase ScatQ
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                                            • SMCF_997
                                            • EHN79464.1
                                            • scatC
                                            		 49721 - 50902 (+) 2-epi-5-epi-valiolone synthase ScatC
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                                              • SMCF_998
                                              • EHN79465.1
                                              • scatJ
                                              		 50895 - 51311 (+) ScatJ protein
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                                                • SMCF_999
                                                • EHN79466.1
                                                • scatM
                                                		 51308 - 52360 (+) C7-cyclitol-7-kinase ScatM
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                                                  • SMCF_1000
                                                  • EHN79433.1
                                                  • scatO
                                                  		 52357 - 53331 (+) putative 2-epi-5-epi-valiolone dehydratase/epimerase ScatO
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                                                    • SMCF_1001
                                                    • EHN79411.1
                                                    • scatT
                                                    		 53270 - 54664 (-) beta-lactamase ScatT
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                                                      • SMCF_1002
                                                      • EHN79434.1
                                                      • scaim
                                                      		 54926 - 55264 (+) alpha-amylase inhibitor Scaim
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                                                        Biosynthesis information
                                                        Annotation changelog

                                                        Entry version: 4

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2022-10-07
                                                        Update chemical activity to schema version 2.11
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 3

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2022-09-15
                                                        Updated bioactivity data
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 2

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2019-10-16
                                                        Migrated from v1.4
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        2019-10-16
                                                        Updated compound(s) information (NPAtlas curation)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                        Entry version: 1

                                                        Date
                                                        Changes
                                                        Submitters
                                                        Reviewers
                                                        2015-06-12
                                                        Submitted
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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