BGC0000804: acarviostatin I03 biosynthetic gene cluster from Streptomyces coelicoflavus ZG0656
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Location: 14,922 - 55,264 nt. (total: 40,343 nt).
This entry is originally from NCBI GenBank AHGS01000039.1.

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core biosynthetic genes
additional biosynthetic genes
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TTA codons
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Gene details
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General
Compounds
Genes
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000804
Short description acarviostatin I03 biosynthetic gene cluster from Streptomyces coelicoflavus ZG0656
Status Minimal annotation: yes
A minimal annotation only contains information on the BGC loci and one or more linked chemical product(s)

Completeness: Unknown
Whether the loci encodes everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • Saccharide
Loci NCBI GenBank: AHGS01000039.1
Compounds
  • acarviostatin I03
  • acarviostatin II03
  • acarviostatin III03
  • acarviostatin IV03
Species Streptomyces coelicoflavus ZG0656 [taxonomy]
References
Chemical products information
acarviostatin I03
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C37H63N1O28
Chemical database entries
PubCHEM
acarviostatin II03
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C56H94N2O40
Chemical database entries
PubCHEM
acarviostatin III03
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C75H125N3O52
acarviostatin IV03
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C94H156N4O64
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • SMCF_976
  • EHN79423.1
  • scatZ2
 14922 - 19781 (-) alpha-amylase ScatZ2
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  • SMCF_977
  • EHN79424.1
  • scatZ1
 19778 - 22906 (-) alpha-amylase ScatZ1
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  • SMCF_978
  • EHN79425.1
  • scatE2
 23020 - 24717 (-) alpha-amylase ScatE2
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  • SMCF_979
  • EHN79426.1
  • scarC2
 25039 - 26106 (-) lacI/galR-like protein ScarC2
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  • SMCF_980
  • EHN79427.1
  • scatE1
 26103 - 27764 (-) alpha-glucosidase ScatE1
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  • SMCF_981
  • EHN79428.1
  • scatG
 27820 - 28725 (-) ABC transporter membrane protein ScatG
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  • SMCF_982
  • EHN79429.1
  • scatF
 28748 - 29755 (-) ABC transporter membrane protein ScatF
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  • SMCF_983
  • EHN79430.1
  • scatH
 29869 - 31143 (-) acarbose/maltose-binding protein ScatH
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  • SMCF_984
  • EHN79453.1
  • scarC1
 31548 - 32576 (+) HTH-type malR-like transcriptional regulator ScarC1
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  • SMCF_985
  • EHN79431.1
  • scatB
 32595 - 33572 (-) dTDP-glucose 4,6-dehydratase ScatB
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  • SMCF_986
  • EHN79432.1
  • scatA
 33650 - 34723 (-) dTDP-glucose synthase ScatA
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  • SMCF_987
  • EHN79454.1
  • scatV
 34956 - 36254 (+) dTDP-4-keto-6-deoxy-glucose 4-aminotransferase ScatV
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  • SMCF_988
  • EHN79455.1
  • scatW
 36251 - 37276 (+) ABC transporter ATP-binding protein ScatW
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  • SMCF_989
  • EHN79456.1
  • scatX
 37273 - 38097 (+) ABC transporter permease protein ScatX
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  • SMCF_990
  • EHN79457.1
  • scatY
 38094 - 38900 (+) ABC transporter permease protein ScatY
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  • SMCF_991
  • EHN79458.1
  • scatU
 38907 - 40370 (+) putative kinase (1-epi-valienol-7-phosphate-1-kinase) ScatU
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  • SMCF_992
  • EHN79459.1
  • scatS
 40390 - 42465 (+) glycosyltransferase ScatS
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  • SMCF_993
  • EHN79460.1
  • scatR
 42515 - 43579 (+) putative 1-epi-valienol-1,7-bisphosphate-1-adenylyltransferase ScatR
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  • SMCF_994
  • EHN79461.1
  • scatK
 43576 - 44502 (+) acarbose-7-kinase ScatK
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  • SMCF_995
  • EHN79462.1
  • scatI
 44520 - 47603 (+) putative glycosyltransferase ScatI
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  • SMCF_996
  • EHN79463.1
  • scatQ
 47600 - 49708 (+) putative acarbose 4-alpha-glucanotransferase ScatQ
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  • SMCF_997
  • EHN79464.1
  • scatC
 49721 - 50902 (+) 2-epi-5-epi-valiolone synthase ScatC
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  • SMCF_998
  • EHN79465.1
  • scatJ
 50895 - 51311 (+) ScatJ protein
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  • SMCF_999
  • EHN79466.1
  • scatM
 51308 - 52360 (+) C7-cyclitol-7-kinase ScatM
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  • SMCF_1000
  • EHN79433.1
  • scatO
 52357 - 53331 (+) putative 2-epi-5-epi-valiolone dehydratase/epimerase ScatO
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  • SMCF_1001
  • EHN79411.1
  • scatT
 53270 - 54664 (-) beta-lactamase ScatT
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  • SMCF_1002
  • EHN79434.1
  • scaim
 54926 - 55264 (+) alpha-amylase inhibitor Scaim
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Annotation changelog
MIBiG version Submitter Notes
1.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Submitted
2.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Migrated from v1.4
  • Updated compound(s) information (NPAtlas curation)
3.0
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Updated bioactivity data
3.1
  • Hidden contributor (ID: AAAAAAAAAAAAAAAAAAAAAAAA, no GDPR consent given).
  • Update chemical activity to schema version 2.11
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