BGC0000814: K-252a biosynthetic gene cluster from Nonomuraea longicatena
Shows the layout of the region, marking coding sequences and areas of interest. Clicking a gene will select it and show any relevant details. Clicking an area feature (e.g. a candidate cluster) will select all coding sequences within that area. Double clicking an area feature will zoom to that area. Multiple genes and area features can be selected by clicking them while holding the Ctrl key.
Location: 1 - 44,760 nt. (total: 44,760 nt).
This entry is originally from NCBI GenBank FJ031030.1.

Legend:

core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
reset zoomreset view
zoomzoom to selection
Gene details
Shows details of the most recently selected gene, including names, products, location, and other annotations.
Select a gene to view the details available for it
General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000814
Short description K-252a biosynthetic gene cluster from Nonomuraea longicatena
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: unknown
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
FJ031030.1
via
Compounds
  • K-252a
Species Nonomuraea longicatena [taxonomy]
References
Chemical products information
K-252a Evidence:
Copy SMILES
C27H21N3O5
Chemical database entries
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • ACN29699.1
3 - 314 (+) putative transcriptional regulator
    copy AA seq
    copy Nt seq
    • ACN29700.1
    947 - 2461 (-) putative amidase
      copy AA seq
      copy Nt seq
      • ACN29701.1
      2635 - 3483 (-) integral membrane protein
        copy AA seq
        copy Nt seq
        • ACN29702.1
        3807 - 4727 (+) putative threonine synthase
          copy AA seq
          copy Nt seq
          • ACN29703.1
          4914 - 7313 (-) ATP-dependent RNA helicase
            copy AA seq
            copy Nt seq
            • ACN29704.1
            7310 - 7627 (-) putative ArsR family transcriptional regulator
              copy AA seq
              copy Nt seq
              • ACN29705.1
              7694 - 8857 (+) putative transmembrane efflux protein
                copy AA seq
                copy Nt seq
                • ACN29706.1
                8811 - 9644 (-) putative integral membrane lipid kinase
                  copy AA seq
                  copy Nt seq
                  • ACN29707.1
                  • nokH
                  9718 - 10524 (-) putative nucleoside-diphosphate-sugar epimerase
                    copy AA seq
                    copy Nt seq
                    • ACN29708.1
                    10600 - 11502 (+) putative transcriptional regulator
                      copy AA seq
                      copy Nt seq
                      • ACN29709.1
                      11499 - 12017 (+) secreted protein
                        copy AA seq
                        copy Nt seq
                        • ACN29710.1
                        12273 - 12920 (+) lipoate-protein ligase B
                          copy AA seq
                          copy Nt seq
                          • ACN29711.1
                          • nokI
                          12923 - 13771 (-) dTDP-dihydrostreptose synthase
                            copy AA seq
                            copy Nt seq
                            • ACN29712.1
                            • nokG
                            13768 - 14697 (-) dTDP-glucose 4,6-dehydratase
                              copy AA seq
                              copy Nt seq
                              • ACN29713.1
                              • nokF
                              14694 - 15758 (-) glucose-1-phosphate thymidylyltransferase
                                copy AA seq
                                copy Nt seq
                                • ACN29714.1
                                • nokK
                                15763 - 16620 (-) carboxylate O-methyltransferase
                                  copy AA seq
                                  copy Nt seq
                                  • ACN29715.1
                                  • nokP
                                  16656 - 17852 (-) cytochrome P450 hydroxylase
                                    copy AA seq
                                    copy Nt seq
                                    • ACN29716.1
                                    • nokM
                                    17866 - 18999 (-) probable sugar O-methyltransferase
                                      copy AA seq
                                      copy Nt seq
                                      • ACN29717.1
                                      • nokJ
                                      18996 - 20192 (-) cytochrome P450 monooxygenase
                                        copy AA seq
                                        copy Nt seq
                                        • ACN29718.1
                                        • nokL
                                        20222 - 21532 (-) N-glycosyltransferase
                                          copy AA seq
                                          copy Nt seq
                                          • ACN29719.1
                                          • nokA
                                          21795 - 23255 (+) L-amino acid oxidase
                                            copy AA seq
                                            copy Nt seq
                                            • ACN29720.1
                                            • nokB
                                            23252 - 26347 (+) chromopyrrolic acid synthase
                                              copy AA seq
                                              copy Nt seq
                                              • ACN29721.1
                                              • nokD
                                              26344 - 27921 (+) monooxygenase
                                                copy AA seq
                                                copy Nt seq
                                                • ACN29722.1
                                                • nokC
                                                27921 - 29150 (+) cytochrome P450
                                                  copy AA seq
                                                  copy Nt seq
                                                  • ACN29723.1
                                                  • nokE
                                                  29104 - 31992 (-) ATP-dependent transcriptional regulator
                                                    copy AA seq
                                                    copy Nt seq
                                                    • ACN29724.1
                                                    32335 - 33846 (-) two-component system sensor kinase
                                                      copy AA seq
                                                      copy Nt seq
                                                      • ACN29725.1
                                                      34546 - 34890 (-) two-component system response regulator
                                                        copy AA seq
                                                        copy Nt seq
                                                        • ACN29726.1
                                                        34932 - 36464 (-) amino acid/metabolite permease
                                                          copy AA seq
                                                          copy Nt seq
                                                          • ACN29727.1
                                                          36530 - 36838 (-) putative integral membrane protein
                                                            copy AA seq
                                                            copy Nt seq
                                                            • ACN29728.1
                                                            36919 - 38553 (+) putative ABC transporter
                                                              copy AA seq
                                                              copy Nt seq
                                                              • ACN29729.1
                                                              38664 - 40469 (+) putative peptide transport system secreted peptide binding protein
                                                                copy AA seq
                                                                copy Nt seq
                                                                • ACN29730.1
                                                                40466 - 41512 (+) putative peptide transport system permease
                                                                  copy AA seq
                                                                  copy Nt seq
                                                                  • ACN29731.1
                                                                  41434 - 42381 (+) putative peptide transport permease
                                                                    copy AA seq
                                                                    copy Nt seq
                                                                    • ACN29732.1
                                                                    42378 - 43352 (+) putative ABC transporter ATP-binding protein
                                                                      copy AA seq
                                                                      copy Nt seq
                                                                      • ACN29733.1
                                                                      43349 - 44341 (+) putative peptide transport ATP-binding protein
                                                                        copy AA seq
                                                                        copy Nt seq
                                                                        Biosynthesis information
                                                                        Annotation changelog

                                                                        Entry version: next

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        MIBiG v4 annotathon
                                                                        • (ID: 4CEPXXFDQQ46VQJXBT4B4AUO)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                        Entry version: 2

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        Migrated from v1.4
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                                        Entry version: 1

                                                                        Date
                                                                        Changes
                                                                        Submitters
                                                                        Reviewers
                                                                        Submitted
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                                        Similar known gene clusters from MIBiG 4.0
                                                                        Shows clusters from the MiBIG database that are similar to the current region. Genes marked with the same colour are interrelated. White genes have no relationship.
                                                                        Click on reference genes to show details of similarities to genes within the current region.
                                                                        Click on an accession to open that entry in the MiBIG database.