BGC0000816: malbrancheamide A biosynthetic gene cluster from Malbranchea aurantiaca
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Location: 1 - 20,179 nt. (total: 20,179 nt).
This entry is originally from NCBI GenBank JQ708193.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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Gene details
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General
Compounds
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Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000816
Short description malbrancheamide A biosynthetic gene cluster from Malbranchea aurantiaca
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
  • other (other)
Loci
JQ708193.1
via
Compounds
  • malbrancheamide A
Species Malbranchea aurantiaca [taxonomy]
References
Chemical products information
malbrancheamide A Evidence:
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C21H24Cl1N3O1
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AGA37261.1
  • malA
 1 - 2004 (-) flavin-dependent halogenase
  • Tailoring
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  • AGA37262.1
  • malB
 3054 - 4163 (+) prenyltransferase
  • Scaffold biosynthesis
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  • AGA37263.1
  • malC
 4886 - 5680 (+) short chain dehydrogenase
  • Tailoring
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  • AGA37264.1
  • malD
 5937 - 7270 (-) negative regulator
  • Regulation
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  • AGA37265.1
  • malE
 8047 - 9459 (+) prenyltransferase
  • Scaffold biosynthesis
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  • AGA37266.1
  • malF
 10457 - 12368 (-) oxidoreductase
  • Tailoring
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  • AGA37267.1
  • malG
 13142 - 20179 (+) NRPS
  • Scaffold biosynthesis
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Biosynthesis information

Biosynthetic modules

Name
0
Type
nrps-type1
Genes
malG
Substrates
proline (evidence: Structure-based inference)
Integrated Monomers
Domains
adenylation
Name
1
Type
nrps-type1
Genes
malG
Substrates
tryptophan (evidence: Structure-based inference)
Integrated Monomers
Domains
condensation (LCL), adenylation
Annotation changelog

Entry version: 4

Date
Changes
Submitters
Reviewers
2022-10-07
Update chemical activity to schema version 2.11
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 3

Date
Changes
Submitters
Reviewers
2022-09-15
Corrected NRP module activity
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2022-09-15
Updated NRP substrate specificities
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 2

Date
Changes
Submitters
Reviewers
2019-10-16
Migrated from v1.4
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
2019-10-16
Updated compound(s) information (NPAtlas curation)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

Entry version: 1

Date
Changes
Submitters
Reviewers
2015-06-12
Submitted
  • (ID: RIBLHRV4YSJAGJ5EVZV4GS2Z)
  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
Detailed domain annotation
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