BGC0000818: notoamide A biosynthetic gene cluster from Aspergillus versicolor
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Location: 1 - 43,815 nt. (total: 43,815 nt).
This entry is originally from NCBI GenBank JQ708194.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
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General
Compounds
Genes
Biosynthesis
History
NRPS/PKS domains
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000818
Short description notoamide A biosynthetic gene cluster from Aspergillus versicolor
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • NRPS (Type I)
Loci
JQ708194.1
via
Compounds
  • notoamide A
Species Aspergillus versicolor [taxonomy]
References
Chemical products information
notoamide A Evidence:
Copy SMILES
C26H29N3O5
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • AGC83572.1
  • notA_
 1 - 1183 (-) negative regulator
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    • AGC83573.1
    • notB_
    		 1772 - 3334 (+) FAD monooxygenase
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      • AGC83574.1
      • notC_
      		 4233 - 5583 (+) prenyltransferase
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        • AGC83575.1
        • notD_
        		 6448 - 8404 (+) oxidoreductase
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          • AGC83576.1
          • notE_
          		 9103 - 15780 (+) NRPS
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            • AGC83577.1
            • notF_
            		 16002 - 17377 (-) prenyltransferase
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              • AGC83578.1
              • notG_
              		 17901 - 19786 (-) P450 monooxygenase
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                • AGC83579.1
                • notH_
                		 20439 - 22242 (+) P450 monooxygenase
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                  • AGC83580.1
                  • notI_
                  		 22791 - 24201 (+) FAD monooxygenase
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                    • AGC83581.1
                    • notJ_
                    		 24352 - 25440 (-) NotJ'
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                      • AGC83582.1
                      • notK_
                      		 27317 - 29288 (+) nucleoside transport
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                        • AGC83583.1
                        • notL_
                        		 30047 - 32195 (+) transcription factor
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                          • AGC83584.1
                          • notM_
                          		 32386 - 34123 (-) NotM'
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                            • AGC83585.1
                            • notN_
                            		 35562 - 37187 (+) NotN'
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                              • AGC83586.1
                              • notO_
                              		 37958 - 39346 (+) NotO'
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                                • AGC83587.1
                                • notP_
                                		 39545 - 40593 (+) short chain dehydrogenase
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                                  • AGC83588.1
                                  • notQ_
                                  		 40679 - 42729 (-) transcription factor
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                                    • AGC83589.1
                                    • notR_
                                    		 43297 - 43815 (+) NotR'
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                                      Biosynthesis information

                                      Biosynthetic modules

                                      Name
                                      1
                                      Type
                                      nrps-type1
                                      Genes
                                      notE_
                                      Substrates
                                      proline (evidence: Structure-based inference)
                                      Integrated Monomers
                                      Domains
                                      condensation (LCL), adenylation
                                      Name
                                      2
                                      Type
                                      nrps-type1
                                      Genes
                                      notE_
                                      Substrates
                                      tryptophan (evidence: Structure-based inference, Homology)
                                      Integrated Monomers
                                      Domains
                                      condensation (LCL), adenylation
                                      Annotation changelog

                                      Entry version: 4

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-10-07
                                      Update chemical activity to schema version 2.11
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 3

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2022-09-15
                                      Corrected NRP module activity
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      2022-09-15
                                      Updated NRP substrate specificities
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 2

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2019-10-16
                                      Migrated from v1.4
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      2019-10-16
                                      Updated compound(s) information (NPAtlas curation)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                      Entry version: 1

                                      Date
                                      Changes
                                      Submitters
                                      Reviewers
                                      2015-06-12
                                      Submitted
                                      • (ID: RIBLHRV4YSJAGJ5EVZV4GS2Z)
                                      • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                      Detailed domain annotation
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