BGC0000818 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000818 (Aspergillus versicolor)

Region	Type	From	To	Most similar known cluster		Similarity
Region 1	NRPS,indole	1	43,815	notoamide A	NRPS:Type I	100%

BGC0000818 - Region 1 - NRPS,indole

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Location: 1 - 43,815 nt. (total: 43,815 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))
indole: (indsynth or dmat or indole_PTase)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene details

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Gene overview

MIBiG

NRPS/PKS domains

MIBiG comparison

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 43,816
Label		BGC0000818

Detailed domain annotation

Selected features only

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Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000818	1.90	NRP	notoamide A	Aspergillus versicolor
BGC0001084	0.94	NRP, Terpene, Alkaloid	notoamide A	Aspergillus sp. MF297-2
BGC0002254	0.80	Polyketide	notoamide F, (+)-semivioxanthin, waikikiamide B, waikikiamide C, notoamide A, waikikiamide A	Aspergillus sp. FM242
BGC0002157	0.69	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0002226	0.67	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0001249	0.67	NRP	dimethylcoprogen	Alternaria alternata
BGC0000687	0.66	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0000900	0.65	Other	ferrichrome	Aspergillus oryzae
BGC0002391	0.65	Terpene	zealexin B2, zealexin C2	Zea mays
BGC0001893	0.64	Other	abscisic acid	Botrytis cinerea B05.10

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000818	1.00	NRP	notoamide A	Aspergillus versicolor
BGC0001084	0.69	NRP, Terpene, Alkaloid	notoamide A	Aspergillus sp. MF297-2
BGC0002157	0.68	NRP, Alkaloid	(-)-ditryptophenaline	Aspergillus flavus
BGC0002226	0.67	NRP	acu-dioxomorpholine B, acu-dioxomorpholine A	Aspergillus aculeatus ATCC 16872
BGC0001249	0.67	NRP	dimethylcoprogen	Alternaria alternata
BGC0000687	0.66	Terpene	phyllocladan-16α-ol	Diaporthe amygdali
BGC0000900	0.66	Other	ferrichrome	Aspergillus oryzae
BGC0002391	0.66	Terpene	zealexin B2, zealexin C2	Zea mays
BGC0002736	0.65	Terpene	preaspterpenacid I	Aspergillus terreus NIH2624
BGC0001528	0.65	Terpene	betaestacin	Phoma betae

Similar known gene clusters from MIBiG 4.0

Module view

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 35780:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Pro - Trp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

notE_

Search NORINE for peptide: strict or relaxed

AMP-binding (82..482): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVMLVGAVNK
Nearest Stachelhaus code(s):: Pro DVMLVGAVNK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1163..1563): Trp

nrpys: Trp

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVYFVGGICK
Nearest Stachelhaus code(s):: Trp DVYFVGGICK (100% 8Å match); Trp or Pro DVYFVGGICK (94% 8Å match)
Stachelhaus code match:: 100% (strong)