BGC0000821: rebeccamycin biosynthetic gene cluster from Lechevalieria aerocolonigenes
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Location: 1 - 26,144 nt. (total: 26,144 nt).
This entry is originally from NCBI GenBank AB090952.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000821
Short description rebeccamycin biosynthetic gene cluster from Lechevalieria aerocolonigenes
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (other)
Loci
AB090952.1
via Enzymatic assays
Compounds
  • rebeccamycin
Species Lechevalieria aerocolonigenes [taxonomy]
References
Chemical products information
rebeccamycin Evidence:
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C27H21Cl2N3O7
Chemical database entries
NPAtlas
PubCHEM
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • BAC10669.1
 422 - 3436 (-) putative regulatory protein
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    • BAC10670.1
    		 3515 - 4147 (-) putative dipeptidease
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      • BAC10671.1
      		 4522 - 5838 (+) putative esterase
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        • BAC10672.1
        		 6701 - 7888 (+) hypothetical protein
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          • BAC10673.1
          • rebG
          		 7961 - 9226 (-) N-glycosyltransferase
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            • BAC10674.1
            • rebO
            		 9436 - 10857 (+) putative L-amino acid oxidase protein
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              • BAC10675.1
              • rebD
              		 10854 - 13895 (+) putative tryptophan metabolite protein
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                • BAC10676.1
                • rebC
                		 13892 - 15481 (+) putative FAD-monooxygenase
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                  • BAC10677.1
                  • rebP
                  		 15478 - 16671 (+) putative cytochrome P450
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                    • BAC10678.1
                    • rebM
                    		 16668 - 17519 (+) putative D-glucose O-methyltransferase
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                      • BAC10679.1
                      • rebR
                      		 17850 - 20621 (+) putative regulatory protein
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                        • BAC10680.1
                        • rebF
                        		 20618 - 21130 (+) putative NADH oxidoreductase
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                          • BAC10681.1
                          • rebU
                          		 21127 - 22407 (+) putative membrane transporter protein
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                            • BAC10682.1
                            • rebH
                            		 22391 - 23983 (+) putative halogenase of tryptophan
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                              • BAC10683.1
                              • rebT
                              		 24053 - 25474 (-) putative translocase protein
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                                • BAC10684.1
                                		 25559 - 26011 (+) hypothetical transcriptional regulator protein
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                                  Biosynthesis information
                                  Annotation changelog

                                  Entry version: next

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2024-04-23
                                  MIBiG v4 annotathon
                                  • (ID: LEEWIYEZSPCYOCCY6BHNTE54)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                  Entry version: 4

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2022-10-07
                                  Update chemical activity to schema version 2.11
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  2022-10-07
                                  Merged data from duplicate entries BGC0000822, BGC0000823
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                  Entry version: 3

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2022-09-15
                                  Corrected biosynthetic class and subclass
                                  • (ID: SJG3CBEHSM6A3I74YXLH6GLA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  2022-09-15
                                  Updated bioactivity data
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                  Entry version: 2

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2019-10-16
                                  Migrated from v1.4
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  2019-10-16
                                  Updated compound(s) information (NPAtlas curation)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                  Entry version: 1

                                  Date
                                  Changes
                                  Submitters
                                  Reviewers
                                  2015-06-12
                                  Submitted
                                  • (ID: RIBLHRV4YSJAGJ5EVZV4GS2Z)
                                  • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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