Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000821.1:
Cluster 1Other126144

BGC0000821, rebeccamycin biosynthetic gene cluster from Lechevalieria aerocolonigenes. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: rebeccamycin
SMILES string: Copy to clipboard
Molecular formula: C27H21Cl2N3O7
Exact molecular mass: 569.0757 Da ([M+H]+)
Molecular activity: Cytotoxic
Molecular target: topoisomerases I and II

Class-specific details

Biosynthetic class(es):
Other
Other biosynthetic class:
Aminocoumarin

Gene cluster description

rebeccamycin (BGC0000821). Gene Cluster 1. Biosynthetic class = Other. GenBank AB090952, positions 1-26144. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Enzymatic assays
MIxS-compliance:Unknown
Contact for this cluster:Fengan Yu (University of Michigan)

Literature references

1. Nishizawa T et al. (2005) Molecular analysis of the rebeccamycin L-amino acid oxidase from Lechevalieria aerocolonigenes ATCC 39243. J Bacteriol 187(6):2084-92. doi: 10.1128/JB.187.6.2084-2092.2005.