LOCUS       BGC0000827             24300 bp    DNA     linear   BCT 28-JAN-2014
DEFINITION  Salinispora arenicola CNS-205, complete genome.
ACCESSION   BGC0000827
VERSION     BGC0000827
KEYWORDS    .
SOURCE      Salinispora arenicola CNS-205
  ORGANISM  Salinispora arenicola CNS-205
            Bacteria; Actinobacteria; Micromonosporales; Micromonosporaceae;
            Salinispora.
COMMENT     URL -- http://www.jgi.doe.gov
            JGI Project ID: 4002390
            Source DNA and bacteria available from Paul Jensen
            (pjensen@ucsd.edu)
            Contacts: Paul Jensen (pjensen@ucsd.edu)
            Paul Richardson (microbes@cuba.jgi-psf.org)
            Quality assurance done by JGI-Stanford
            Annotation done by JGI-ORNL and JGI-PGF
            Finishing done by JGI-PGF
            Finished microbial genomes have been curated to close all gaps with
            greater than 98% coverage of at least two independent clones. Each
            base pair has a minimum q (quality) value of 30 and the total error
            rate is less than one per 50000.
            The JGI and collaborators endorse the principles for the
            distribution and use of large scale sequencing data adopted by the
            larger genome sequencing community and urge users of this data to
            follow them. It is our intention to publish the work of this
            project in a timely fashion and we welcome collaborative
            interaction on the project and analysis.
            (http://www.genome.gov/page.cfm?pageID=10506376).
            ##antiSMASH-Data-START##
            Version      :: False
            Run date     :: 2024-10-17 14:16:39
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 2672472
            Orig. end    :: 2696772
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..2946
                     /codon_start=1
                     /db_xref="InterPro:IPR000792"
                     /gene_functions="regulatory (smcogs) SMCOG1149:LuxR family
                     transcriptional regulator (Score: 214.6; E-value: 4.4e-65)"
                     /gene_kind="regulatory"
                     /locus_tag="Sare_2326"
                     /note="PFAM: regulatory protein LuxR; KEGG: msm:MSMEG_4431
                     putative regulatory protein"
                     /product="ATP-dependent transcriptional regulator,
                     MalT-like, LuxR family"
                     /protein_id="ABV98184.1"
                     /transl_table=11
                     /translation="MTPVLASSRDGPARAVGRNVLGKSVPPVRIHAHPLRKVRGWEEHL
                     EQISTDLRRVVSDRRSRVLMVKAAPGGGKTRLLAEAATVADDMGFTIVGGVVAGPDAVP
                     DMAHLPAATQVRVAGSSTDRFSSPRATSLVEATGARLRRAANDVPTVVTLDDLHLADFP
                     TLMALCDLILALKGRPILWLLTFTSATSAAPSEQASMCLSRLRGRVAVEPIRRLSPLSN
                     EALEQLVTDHTGSVPDPTLLALVESLNDTPSAVIELIRGLMEDGVICTVEGTLRLTPGT
                     PGSSRDVNAVHVPAPVPKRLSSMIEENLLRLSDSTVKSLRLAAVLGSPFAPEELSAMLD
                     ESPAGLLTAVHEAVERGVLVCCGQNLAFRTESIWRVLLDSVPPPVRALLRRQAAETLLR
                     RPDGAERAALQLVHVARPGDAKDLDVIAEGARRLVATDPTTAASLAIRGMELLDPGQDQ
                     RVRLANTAVKALTKVGRLDEAVTLARDEIEVAAAPTSVPPARDIAALQASMSTALLLRG
                     DASAARQATDDVLARQAGGLPRAEVVITRLAASYLIGDSTAVEQARTILSRPDRRDRAV
                     RVSAMTVHALDRWRTGHVVDAVGILRDAVALNHVGETVQVLDPCCFLAFALVRIDEFGE
                     AEEVVRGYGRTTASTESSPATAVQAVLRAPLHLAQGQLNEAEQVARVALRQDGPYMPVF
                     APQAFLVLAHVALRRGTPAQAAIHLKALEGEGLQHSSSPWQAEYLLLQAQLAEVNDGPA
                     AALEVLTETGAQPITPREIVLEDPAVAAWWVRCALTADQPEIAGGVVDTIEDLSKLNPE
                     VPALFAAATHARALAEADTDALAEAGRLHRNPWARAATAEDRARIFLFRGDHESAITEL
                     DCAMNAYNQLGAEREAARVRAQLRGLGVWRRHWKQAKRPLSGWESLTETERKVAKLVAN
                     GLTNQQAADHLFISPHTVGFHLRQIYRKLGIRSRSALIRYDASRVSRPEAS"
     subregion       1..24300
                     /aStool="mibig"
                     /contig_edge="False"
                     /label="other"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..24300
                     /contig_edge="False"
                     /product="unknown"
                     /region_number="1"
                     /subregion_numbers="1"
                     /tool="antismash"
     gene            1..2946
                     /locus_tag="Sare_2326"
     gene            complement(3259..4485)
                     /locus_tag="Sare_2327"
     CDS             complement(3259..4485)
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002397"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 251.7; E-value: 2e-76)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2327"
                     /note="KEGG: sen:SACE_5814 cytochrome P450-like enzyme"
                     /product="Cytochrome P450-like protein"
                     /protein_id="ABV98185.1"
                     /sec_met_domain="p450 (E-value: 9.3e-17, bitscore: 50.9,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTTNTELTEAPETNMPVDPGLFDCMPDLIAAARVAPVVRIPYL
                     GRHAWVVCDRELVKQALTHPKMGKDIALVPEWMRQPGLMVTAQPDPEYARAMIMSDGEN
                     HARIRRIHAPVLSPRNTERWGERVADKVEGFLDELSQAGSGGSAEVNVVTNYTHKIPLA
                     FISEMLGLPPEAEHRLRGITDIMLYSSDYAARREAIGGLFGAVEDWVRNPADLRDGVIT
                     GLLAASDGPDAAVTEGEVIVWTLGMIITGYETTGSLISTSLYEAIRRPPHERPKTDEDI
                     TAWIEETLRVHPPFPHPTWRFPLEDIELGGYLIPKGAPVQVSIAAANRKPGEGADSFDA
                     ERRGHGHLSFGLGMHYCIGAPLVRLEAQIAVRGFLRRFPQARLSAETAVQWESEWMIRR
                     MSVLPAVLS"
     gene            complement(4482..5783)
                     /locus_tag="Sare_2328"
     CDS             complement(4482..5783)
                     /codon_start=1
                     /db_xref="InterPro:IPR002213"
                     /db_xref="InterPro:IPR004276"
                     /db_xref="InterPro:IPR006326"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 259.5;
                     E-value: 1.1e-78)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2328"
                     /note="TIGRFAM: glycosyltransferase, MGT family; PFAM:
                     UDP-glucuronosyl/UDP-glucosyltransferase; glycosyl
                     transferase family 28; KEGG: dra:DR_A0329
                     glycosyltransferase, putative"
                     /product="glycosyltransferase, MGT family"
                     /protein_id="ABV98186.1"
                     /sec_met_domain="MGT (E-value: 3.6e-54, bitscore: 174.6,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLIATTPAPGHVVSMVDVAGELTRRGHEVRWYTGRAFQEQVEQAG
                     ARFEPMSEALDFGGRSREEAFPSHAGLTGLASFKIGVRDIFYHTAPGQLDDLLRVLERF
                     PADCILADDMCYGACFASERTGLPMAWLSNSIYILGSRDTAPLGLGLQPSSSPLGRARN
                     ALLRFLGDHVSMRDLRREADRTRASVNLPRLRTRAMENITRPPDLYLVSTVPSFEFSRS
                     DLLPGTHFIGGLFGLPPERFEPPSWWQELDGDKPVVLITQGTTANDVDRLLVPAVRALA
                     REDLLVVVTTGSDLDVDLLRPLPGNVRLERFVSYHHLLPRVDVMLTNGGYNGVNAALAH
                     GVPLVAAPATEENPDVAARIAWSGAGVVLARRAVSEATLRNAVVTVLHDERYRQRAHVL
                     SREHQRYDAPRRAAELIEAMAESQGRVPTGGPTQ"
     gene            6071..7582
                     /locus_tag="Sare_2329"
     CDS             6071..7582
                     /codon_start=1
                     /db_xref="InterPro:IPR000759"
                     /db_xref="InterPro:IPR001613"
                     /db_xref="InterPro:IPR002937"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2329"
                     /note="PFAM: amine oxidase; KEGG: rrs:RoseRS_2594 amine
                     oxidase"
                     /product="amine oxidase"
                     /protein_id="ABV98187.1"
                     /sec_met_domain="DAO (E-value: 1.5e-10, bitscore: 31.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAALRNSGGSESAINGQKRVTVIGAGIAGLVTAYELERLGHRVEI
                     IEASPDVGGRIDTHRFAVDGRPGPFAELGAMRIPAGHRLTRHYIAELGLQDQVHRFQTL
                     FSDDHAYLPSSGGYVRVGDAHETLVKEFVAGLPNRQYRENTLLFGAWLDATIRAVAPRQ
                     FYDGMHNEIGAELLDLIDGIDLTPYRCGSSGNRIDLHAFYADHPLIRSLCPPHLERFLD
                     DVLDETGSNIIRLRSGMDMLPRRLAAQIRGPISTGREVVGIEIQQDSVLLHVRHGAKTI
                     ATSCDYVVCTIPFTVLRAMRLVGFDQDKLDIVHQTKYWPATKVALHCREAFWKKDGISG
                     GASFTGQHVRQTYYPPVDGDPALGAVLLASYSIGPDAEALGRLSEAERNALIIRELSEM
                     HPELRAPGMILGVASRAWGRHRWSLGAATVRWGQGAALRESERREAVRPQRRLFFAGEH
                     CSSKPAWIEGAIESAIDAAHEIEWHELRADREFATTRSSRLGKLA"
     gene            7579..10788
                     /locus_tag="Sare_2330"
     CDS             7579..10788
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indsynth"
                     /gene_kind="biosynthetic"
                     /locus_tag="Sare_2330"
                     /note="KEGG: cvi:CV_3273 VioB - polyketide synthase"
                     /product="VioB - polyketide synthase"
                     /protein_id="ABV98188.1"
                     /sec_met_domain="indsynth (E-value: 0.0, bitscore: 1648.9,
                     seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVFDLPRLHFRGSATTHLPTGPRNGLVDLATNTALTEDGRAFPV
                     ASPAHAYHDYLDQVGPRFDLAGRPCADGPFSVAKGRDFAGNGHFSVDARIVSVEVRTSE
                     INTVDPVVGRTVDMWGHYNEYLGTTVNRARVFDVDPASNRTTTLMVGQFGFGRDGRSHD
                     VGYLATGRVHGFVPPRWHNADHAVDIDDHWQANDLRRSVVHQFVVTADELTWLDEPAAS
                     PAVRLLRDTDASGLVVQFSLSRMSVPSAPDQPSRWQLNGTIAPWYPHEPRTYPAGRLLV
                     PDSRGPSRTDGRLHNLSVELTDTHAILNMITAVPTVGTGPVDVGDLELRTAGDGRLVAR
                     LPREAYLGQEYLLACGLVTVPIEMSAEAASEEPLSLVSRRPGGPVRQLREREVNVQVDE
                     SALILEHPRDAEDAHHDVEVPVRAFVRGRPGAVHEIAVRQFFNPRALPGEAAARSPKAR
                     CSDIDVLRLRPGRLDEAGGWSSACVLGTDQAGCGWFTMRGATAGTALVLLSTDADDLPC
                     DPEAPGSATLAYDHDDVLGYWPGAGYLSIRVLPDDWRLAGLEQKDVTFELVYREVFAFY
                     EHLFSFMKAEVFSLADRCKVETYAKLIWQMCDPRNKAKTYYMPPTRDLSEPKARLLLKY
                     LRAQQVPDAVLLTAPATNRRSRRIATRDQLVRVLREAAKVELAVMLQYLYAAYSVPAYG
                     VGLEYVRQGGWTREQLRLACGDGGETLDEGVRSMLLNIAREEMIHFLLVNNILVAMGEP
                     FHVPWIDFATINHELPVPLDFCLEGMGIGSVERFTMIERPESHVPDVLGTGGATAQDDG
                     HTYASLSDLYSAIREGLQHIPGLFLVDKGRGGGEHHLFLRESINSRHPDYQLEVDDLSS
                     ALFAIDVITEQGEGGVLTAGPDEVSHYTSFLRIGELLRGAVAPGGDPWHPAYPVLRNPT
                     LRHGERAMETVTDPDARTVMALFNRAYFMALQLMAQHFGERPDGSLRRSDLMNGAIDMM
                     TGLMRPLAELLVTMPSGRRGRTAGPSFELVEQPTPVSRPEVARRGIALRLDDLAAECGK
                     SALVPTRVGEMSAFWADHFRP"
     gene            10854..12107
                     /locus_tag="Sare_2331"
     CDS             10854..12107
                     /codon_start=1
                     /db_xref="InterPro:IPR001128"
                     /db_xref="InterPro:IPR002397"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 378.7; E-value:
                     5.1e-115)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2331"
                     /note="PFAM: cytochrome P450; KEGG: art:Arth_1978
                     cytochrome P450"
                     /product="cytochrome P450"
                     /protein_id="ABV98189.1"
                     /sec_met_domain="p450 (E-value: 2.6e-20, bitscore: 62.7,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSATLPRFALTGWSRENIVNPYPVYQRYREVASVHRGEPGGDAP
                     DTFYVFSYDEVVQVLSSNCFGRGRSLDAAKASVPVPAEQKALRAIVENWLVFMDPPRHT
                     ELRSLLNRSFSPRIVTELRPRIARIAQELLSRLGQQVDVDLVESFAAPLPILVISELLG
                     IPEERRAWLRANALALQEASSSRAGRDVDGYAQAEVAAQEFTEYFREQVRLRRGRAGGD
                     LITILANAQERGAPVSLDAIVGTCVHLLTAGHETTTNSLAKAVLALREHPAVLDELRGA
                     EGLTTDAVEEFLRYDPPVQAVTRWAHQDTTLGGCDIPRGSRVVALLGSANRDPARFPSP
                     DVLDVRRPADRHLSFGLGIHYCLGATLARAELEIGLQALLDGVPTLGYGTQHVDYADDL
                     VFHGPSRLVLVNLGERCK"
     gene            12107..12946
                     /locus_tag="Sare_2332"
     CDS             12107..12946
                     /NRPS_PKS="Domain: oMT (33-222). E-value: 1.5e-37. Score:
                     120.6. Matches aSDomain: nrpspksdomains_Sare_2332_oMT.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR003333"
                     /db_xref="InterPro:IPR004033"
                     /db_xref="InterPro:IPR013216"
                     /db_xref="InterPro:IPR013217"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 194.8; E-value: 3e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2332"
                     /note="PFAM: Cyclopropane-fatty-acyl-phospholipid synthase;
                     UbiE/COQ5 methyltransferase; Methyltransferase type 11;
                     Methyltransferase type 12; KEGG: rrs:RoseRS_3510
                     methyltransferase type 11"
                     /product="Methyltransferase type 11"
                     /protein_id="ABV98190.1"
                     /transl_table=11
                     /translation="MSKVSSQPVPKAVGELYDRLTLSAMTDGTFNPNVHIGYWDSPEST
                     ASVDEAMDRLTDVFIERLKVGASNHVLDLGCGVGGPGLRVVAQTGARVTGISISEEQVK
                     SANRLAAEAGVADRAVFQHGDAMRLPFPDHSFDAVMALESMCHMPDRQQVLTEVCRVLV
                     PGGRLVLTDVFERFPRKEVRHQGIDKFCNDLMSTTADLDDYVAMLHRSGLRMRELLDVT
                     EQTTLRLAYELAKLPVLQERPAALNEGNFEFSDDAFKPSDLEGVDDFGCLLATAERP"
     aSDomain        12206..12772
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Sare_2332_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.50E-37"
                     /label="Sare_2332_oMT.1"
                     /locus_tag="Sare_2332"
                     /protein_end="222"
                     /protein_start="33"
                     /score="120.6"
                     /tool="antismash"
                     /translation="VHIGYWDSPESTASVDEAMDRLTDVFIERLKVGASNHVLDLGCGV
                     GGPGLRVVAQTGARVTGISISEEQVKSANRLAAEAGVADRAVFQHGDAMRLPFPDHSFD
                     AVMALESMCHMPDRQQVLTEVCRVLVPGGRLVLTDVFERFPRKEVRHQGIDKFCNDLMS
                     TTADLDDYVAMLHRSGLRMRELLDVT"
     gene            13036..14646
                     /locus_tag="Sare_2333"
     CDS             13036..14646
                     /codon_start=1
                     /db_xref="InterPro:IPR002938"
                     /db_xref="InterPro:IPR003042"
                     /db_xref="InterPro:IPR006076"
                     /db_xref="InterPro:IPR013027"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050:monooxygenase FAD-binding (Score: 313.6; E-value:
                     4.3e-95)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2333"
                     /note="PFAM: monooxygenase FAD-binding; FAD dependent
                     oxidoreductase; KEGG: bxe:Bxe_C1006 putative flavoprotein
                     monooxygenase"
                     /product="monooxygenase FAD-binding"
                     /protein_id="ABV98191.1"
                     /transl_table=11
                     /translation="MTNSGEWTDVLIVGGGPVGMALALDLRYRGIDCMVVEAGDGEVRH
                     PKVSTIGPRSMELFRRWGLADTIRNAGWPADHPLDIAWVTRVGGHEVHRYRRGTTANRG
                     PYVHTPEPDQICPAHWLNPLLQRAVGVHPTGPLRLRTTVDRVRQAADHVEATLVEDGSG
                     RTGTVRAQFLVACDGAASPIRQACGIDAPPRHTTQVFRNILFRAPELKRQLGDRVALVY
                     FLVRSSTLRFPMRSLNGSDLYNLVVGVDAAAQVDGRSLITDAIAFDTPVELLSDSQWHL
                     THRVADSYRAGRVFLAGDAAHTLSPSGGFGLNTGFGDVADLGWKLAAALNGWAGCHLLD
                     TYEAERRPIALESLQEANLNLQRTMRRHVPAEIHADGPAGEQARAEMAEQLVRGGAHRE
                     FDAPEIHFGLSYRSPAVISDPLVPPRQGQPDAAWRPGSDPGYRAAHAWWDTETSTLDLF
                     GHGFVLLSFTEGADVSAVERAFAKRAVPLTVRRGSDPEIAKLYERSLVLVRPDGHVAWR
                     GDELPADLGKFVDTIRGEY"
     gene            14648..14806
                     /locus_tag="Sare_2334"
     CDS             14648..14806
                     /codon_start=1
                     /locus_tag="Sare_2334"
                     /product="hypothetical protein"
                     /protein_id="ABV98192.1"
                     /transl_table=11
                     /translation="MQPGRNSRQWPDQETVTPIAEVGALEEGLPVAPATFRMLFRYGEG
                     EYMEVVV"
     gene            14803..15726
                     /locus_tag="Sare_2335"
     CDS             14803..15726
                     /codon_start=1
                     /db_xref="InterPro:IPR005835"
                     /db_xref="InterPro:IPR005907"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 281.1; E-value:
                     1.6e-85)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2335"
                     /note="TIGRFAM: glucose-1-phosphate thymidylyltransferase;
                     PFAM: Nucleotidyl transferase; KEGG: sen:SACE_6883
                     glucose-1-phosphate thymidylyltransferase"
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="ABV98193.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 5e-13, bitscore:
                     39.9, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGIVLAGGYGTRLHPITLGVSKHLLPVYDKPMIYYPLSVLMLAG
                     ITDIKIISSPDDLPLFQRLLRDGSQFGLSLSYAEQDKPRGLADAFRIGADHIGDDSVAL
                     VLGDNIFHGPGFSDLLQRSVVDIDGCVLFGYPVRDPERYGVGEVDARGRLVELVEKPAQ
                     PRSNLAITGLYLYDNEVVEIARDLQPSARGELEITDVNRVYLQRGKAELVSLGRGFVWL
                     DTGTHDALTEASQYVQIMEHRQGVRVACLEEIAWRMGFIDQEACHRLGRQLAKSPYGQY
                     VMEVTAAAGGPVAVTNWPATVRRGRQ"
     gene            15723..16796
                     /locus_tag="Sare_2336"
     CDS             15723..16796
                     /NRPS_PKS="Domain: NAD_binding_4 (4-186). E-value: 8.9e-21.
                     Score: 66.0. Matches aSDomain:
                     nrpspksdomains_Sare_2336_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR003869"
                     /db_xref="InterPro:IPR005888"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     347.4; E-value: 1.3e-105)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2336"
                     /note="TIGRFAM: dTDP-glucose 4,6-dehydratase; PFAM:
                     NAD-dependent epimerase/dehydratase; 3-beta hydroxysteroid
                     dehydrogenase/isomerase; polysaccharide biosynthesis
                     protein CapD; dTDP-4-dehydrorhamnose reductase; Male
                     sterility domain; KEGG: stp:Strop_2222 dTDP-glucose
                     4,6-dehydratase"
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="ABV98194.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.2e-21, bitscore:
                     65.1, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3.4e-22,
                     bitscore: 69.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 2.7e-21, bitscore:
                     66.0, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILVTGGAGFIGSHYVRSLLAGEYAAEDAVGAVDASVTVLDKLT
                     YAGNRANLPATHPRLTFVQGDICDQGLLRDLFKGHDAILHFAAESHVDRSVDGGATFVR
                     TNALGTQSVLEAAVAVGVPRVVHVSTDEVYGSIEHGAWTETWPLLPNSPYAASKASADL
                     IARSYWRTHGLDVSITRCSNNYGPYQHPEKLVPLFITNLLEGLPVPVYGTGVNVREWLH
                     VADHCRALHRVLTRGRPGEVYNVGSGNELTNLELTERLLHLCGADRSMIRYVTDRKGHD
                     QRYSLDDTKIRECLGYRPRVSFADGLAETVAWYRDNPQWWKAARHGAPKTTEAAPRATT
                     GVVRGTHNRIDDQEPPK"
     aSDomain        15735..16280
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_Sare_2336_NAD_binding_4.1"
                     /evalue="8.90E-21"
                     /label="Sare_2336_NAD_binding_4.1"
                     /locus_tag="Sare_2336"
                     /protein_end="186"
                     /protein_start="4"
                     /score="66.0"
                     /tool="antismash"
                     /translation="VTGGAGFIGSHYVRSLLAGEYAAEDAVGAVDASVTVLDKLTYAGN
                     RANLPATHPRLTFVQGDICDQGLLRDLFKGHDAILHFAAESHVDRSVDGGATFVRTNAL
                     GTQSVLEAAVAVGVPRVVHVSTDEVYGSIEHGAWTETWPLLPNSPYAASKASADLIARS
                     YWRTHGLDVSITRCSNNYG"
     gene            16793..17914
                     /locus_tag="Sare_2337"
     CDS             16793..17914
                     /codon_start=1
                     /db_xref="InterPro:IPR000653"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     397.5; E-value: 1e-120)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2337"
                     /note="PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; KEGG:
                     gur:Gura_4276 glutamine--scyllo-inositol transaminase"
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase"
                     /protein_id="ABV98195.1"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 9.8e-120,
                     bitscore: 390.2, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTHVWDYLPEYAKEKDDILDAVQTVFGSGQLVLGESVRGFEREF
                     AAYHSLPYATGVDNGTNALKLGLEALGVGPGDEVITVSNTAAPTVVAIAGAGATPVFVD
                     VREDDFLMDTDQVAAAITPRTRAILPVHLYGQCVDMAPLGRLAEEHGLRILEDCAQSHG
                     ARHHGRLAGTMGDAAAFSFYPTKVLGAYGDGGAVITADESIDRHLRQLRYYGMDKVYYV
                     VRTPGHNSRLDEVQAEILRRKLRRLDEYVAGRNAVARRWEQLLGDLSGPGGLRLPTTNP
                     GNTHVHYVYVVRHPQRDAIIQALRAHDISLNISYPWPVHTMDGFAHLGYTEGSLPVTER
                     LAREIFSLPMYPSLPESEQERVAAALREVLAGL"
     gene            18033..18635
                     /locus_tag="Sare_2338"
     CDS             18033..18635
                     /EC_number="5.1.3.13"
                     /codon_start=1
                     /db_xref="InterPro:IPR000888"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2338"
                     /note="PFAM: dTDP-4-dehydrorhamnose 35-epimerase related;
                     KEGG: sma:SAV949 dTDP-4-keto-6-deoxyhexose 3,5-epimerase"
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="ABV98196.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 1.2e-50,
                     bitscore: 161.7, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVRRLAIDGAVEFTPSVHRDERGLFASPYQEPAFTATFGWPLFP
                     VRDLSHNVSARGVLRGIHFTSTPPGRAKYVYCPYGKVQDFLIDLRVGSPTFGCWDSTEL
                     GGDTCRAIYIPVGVGHAFLSLVDDSMIVYAMSKGYVAEDELAISPLDPALGLPLPAGIT
                     PLQSDRDRAAPTLAEALDRGLLSDDAVCRDVEAKLWQ"
     gene            18626..19630
                     /locus_tag="Sare_2339"
     CDS             18626..19630
                     /codon_start=1
                     /db_xref="InterPro:IPR001509"
                     /db_xref="InterPro:IPR002225"
                     /db_xref="InterPro:IPR005913"
                     /db_xref="InterPro:IPR013120"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     195.8; E-value: 1.9e-59)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2339"
                     /note="PFAM: NAD-dependent epimerase/dehydratase; 3-beta
                     hydroxysteroid dehydrogenase/isomerase;
                     dTDP-4-dehydrorhamnose reductase; Male sterility domain;
                     KEGG: stp:Strop_2216 NAD-dependent epimerase/dehydratase"
                     /product="NAD-dependent epimerase/dehydratase"
                     /protein_id="ABV98197.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 8.6e-15, bitscore:
                     44.7, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVKRPLVVLLGATGFVGSAVLRELAVRDVRVRAVSRGAASVPED
                     ARAEIEVHTADLTEPGRLAQAIAGADVVIHTIAYIAGSTTWRINEGDSAAERVNVGLVR
                     DLVAVLRDGDRNLPPLPVVFAGAVSQVGPTDKEVLDGSEPDWPQGEYDRQKLAAERVLL
                     DAHAERILRAVSIRLPTVFGYGPRSTARDKGVVSTMVRRALAGEPITMWHDGTVRRDLL
                     YVEDVARALVAAVDHVDALAGRPWLLGSGRGLPLGEVFTTVASLVAERTGKPPVRVVSV
                     PPPEHAEPGDFHNITIDATPFRSVSGWRPKVPLTDALRHTVDFCASGAEEGLS"
     gene            19704..21101
                     /locus_tag="Sare_2340"
     CDS             19704..21101
                     /codon_start=1
                     /db_xref="InterPro:IPR005212"
                     /locus_tag="Sare_2340"
                     /note="PFAM: NDP-hexose 23-dehydratase; KEGG: sma:SAV950
                     dTDP-4-keto-6-deoxy-L-hexose2,3-dehydratase"
                     /product="NDP-hexose 23-dehydratase"
                     /protein_id="ABV98198.1"
                     /transl_table=11
                     /translation="MTAPTVLRLRADDTLAQRLARSAALRAEGFALRTADVAGWLTQRA
                     RAHHFRVERIALNDLDGWFFATDTGNLHHHTGRFFSIEGIDVNHNEGAIRRWQQPMIRQ
                     PEVGILGILAKEFDGVLHFLLQAKMEPGNRNLLQLSPTVQATHSNYTGAHRGTPVKYLE
                     YFTDPSRGTVLTDVLQSEHGSWFYRKSNRNIVMETVDDVPVDDDFCWLTLGQIGELLRY
                     DNVVNMDARTVLASCPVTSAEPGALNTDMELRSWFTVERSRHSLTAERVPLADIEEWKR
                     SDFTLGRDDGRYFRLVAVAVEAGNREVTGWSQPLFEPTGIGVSAFLFRHFGGVPHLLVQ
                     AKVEAGFLDTVELAPTVQCTPGNWAHLPEPLRPYFLDVVRVAGPDRVRYAAVHSEEGGR
                     FLNAESRYLFVEADEAQAPLDPPTGFRWATPGQLNNLAQHGHYLNVQARTLLACLNAGT
                     VRLDPTR"
     gene            21355..22755
                     /locus_tag="Sare_2341"
     CDS             21355..22755
                     /codon_start=1
                     /db_xref="InterPro:IPR002129"
                     /db_xref="InterPro:IPR010107"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1180:Decarboxylase, pyridoxal-dependent (Score: 101.4;
                     E-value: 7.5e-31)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2341"
                     /note="TIGRFAM: glutamate decarboxylase; PFAM:
                     Pyridoxal-dependent decarboxylase; KEGG: stp:Strop_4374
                     glutamate decarboxylase"
                     /product="glutamate decarboxylase"
                     /protein_id="ABV98199.1"
                     /transl_table=11
                     /translation="MPNTRRSIDSFGPGVVGLNPMFARPGEATELARFSIPDDESLPET
                     AYQIVHDEVALDGNARLNLATFVGTWMDSHAEKLFAETFDKNLIDKDEYQATDVIETRC
                     RTILADLWHAPEPRNAVGTSTIGSSEACMLGGLALKRRWQHARRSAGQSTDRPNLVMSS
                     AVQVCWKKFCNYWDVEARTVPISEERRVLDGHDLRSYVDENTIGVVALLGVTYTGMYEP
                     VERIAAALDDIQAATGWDIPIHVDGATGAFIAPFIQPDLVWDFRIGRVASINASGHKYG
                     LVYPGLGWIVWRDQVALPDDLRFRVAYLGGDTPTVGLSFTRPGSHVLLQYYLFLRLGRD
                     GFRRVQQATHDVAQYLSREIAAMPQFELWSDGSDIPVLTWHLRKGPSWNWNLYHLSDRL
                     RMKGWKVPTYPMPEDLTDLTVQRIVVRNGLSRDLAGVFIADLHAEVAFLESLTVPITTL
                     GQRPGFHH"
     gene            22774..24300
                     /locus_tag="Sare_2342"
     CDS             22774..24300
                     /codon_start=1
                     /db_xref="InterPro:IPR004841"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038:phenylalanine-specific permease (Score: 172.5;
                     E-value: 1.8e-52)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="Sare_2342"
                     /note="PFAM: amino acid permease-associated region; KEGG:
                     stp:Strop_4375 amino acid permease-associated region"
                     /product="amino acid permease-associated region"
                     /protein_id="ABV98200.1"
                     /transl_table=11
                     /translation="MAPSAARPPAKNSAKITVLGLAMLNIVAVVSLSGLPAEAEYGLSA
                     AFYYIFAAIFFLVPVSLVAAELATAWPEKGGVFRWAGEAFGGRWGFVAIFLLIAQVTIW
                     FPVVLTFGAISLAYTGPQATLDQKLSGNRLYILLTVLAVYWIATAIGSRGMAAFTRIAK
                     WGGIVGTILPAAVLVTLGFAYLSTGGQSQIPLRWGDVVPDFSRVSNLVLAASIFLFYAG
                     MEMNAIHVRDVRSPSRHYPLAVGIAAVGTMSILVLGTLAIAFVVPQSDIDLTQSLLITF
                     IDVFQWLGLSWAAPVVAVALTIGVLAGIVTWVVGPSTAMLAVAKAGYLPPFFQATNKSG
                     MPTHILLVQAVAVSVLAVLFVFMPSVQAAFQVLSQLAGLLYLVVYLAMFASAISLRYSQ
                     PDRRRPYRVPGGLAGMWVIGGVGFVASALALASSLVPPSQIGVGNPFLYIGLLVGLAGL
                     IVTVPLVVYARRKPHWHDPASDVAPFAWEARGARSGAAETRGRRTNDADE"
ORIGIN
        1 gtgacgccag tattggcatc atcacgcgat ggacctgcac gagctgtggg gaggaacgtc
       61 ttgggtaagt ctgtgccgcc ggtgcgcatt cacgcacacc cgttgcggaa ggtgcgtggc
      121 tgggaggagc acctggagca gatcagtacc gatctgcgtc gcgtcgtgtc cgaccggcgg
      181 agccgggtgc tcatggtgaa ggcagcgccc ggcggcggta agacccgatt actggccgag
      241 gcggccaccg tcgccgacga catgggcttc accatcgtcg gtggtgtcgt ggctggtcct
      301 gatgcggtgc ctgacatggc gcacctgccg gccgctactc aggtccgggt ggctggcagc
      361 agcacagacc gattctccag tccacgggcg acctccctgg tcgaggcgac gggggcgcgg
      421 ctgcgtcggg ccgcgaatga cgttcccacc gtggtgaccc tcgatgacct gcacctggcc
      481 gactttccca ccctgatggc gttgtgtgac ctgattctgg cgctcaaagg ccgaccgatc
      541 ctctggctgc tgacctttac ctccgcgacg agcgccgcgc cctccgaaca agcgtcgatg
      601 tgtttgagtc gacttcgggg cagagtggcc gtcgaaccga tccggcggtt gagtccgctc
      661 tcgaacgagg cactggagca actggtcacc gaccataccg gctccgtccc cgacccaacg
      721 ctgctcgccc tggtggaaag cctcaacgat acgccctccg cagtgatcga gctgatacgt
      781 gggctcatgg aggacggtgt catctgcaca gtcgagggca ccctacggtt gacccctggt
      841 acgcccggca gctcccgcga cgtgaatgct gttcatgtgc ccgcaccagt gccgaagcga
      901 ctatcctcaa tgatcgagga gaatctccta cgactttctg attcgactgt caagtccctt
      961 cgattggcgg ccgtgctcgg atcaccgttc gcgccggagg aactgtcggc catgctcgac
     1021 gaatcaccgg ctggcctact caccgcggtg catgaggcgg tggaacgcgg agtactggtc
     1081 tgttgtgggc agaatctggc attccgcacc gagtcgatct ggcgggtact acttgactct
     1141 gtgccgccac cggtacgcgc gttgttgcgt cggcaggcgg ccgaaacgtt gctgcgacgt
     1201 cccgacgggg ccgaacgtgc cgcccttcaa ctggtgcacg tggctcgacc cggtgacgcc
     1261 aaggatctcg acgtcatcgc cgaaggagcc cgacgcctcg tcgccaccga tcccaccacc
     1321 gcagcatccc tggcgatccg tgggatggaa ctgctggacc ccggacagga ccaacgcgtg
     1381 cgtcttgcca ataccgcggt gaaggcactc accaaggtgg ggcgcctgga cgaggcggtc
     1441 acgctggcca gggacgagat cgaggtggcc gcggccccca cctcggtgcc acccgcccgt
     1501 gacatcgccg ccttgcaggc gtcgatgtcg accgcgttgc tgctgcgagg cgacgcgtcg
     1561 gccgcccgcc aagcgaccga cgacgtactg gccaggcagg cgggcggact cccccgggcc
     1621 gaggtggtca tcacccgtct cgccgcttcc tacctgattg gtgacagtac ggcggtcgag
     1681 caggcacgta cgatcctcag caggcccgac cgacgcgacc gggcggtcag ggtcagcgcg
     1741 atgactgtcc acgcgttgga tcggtggcga actggccacg tggtggacgc ggtggggatc
     1801 ctgcgggacg ctgtcgcgct caaccatgtc ggtgagaccg ttcaggtcct cgacccgtgc
     1861 tgtttcctcg ccttcgcgct tgtccggatc gacgagttcg gtgaggcgga ggaggtcgtt
     1921 cgagggtatg gcagaacgac cgcctcgacg gagagttctc cggctaccgc agtccaggcc
     1981 gtgcttcgcg cgcccctgca cctcgcccag gggcagctga acgaagccga acaggttgcc
     2041 cgagtcgcgt tgcgacagga cggcccttac atgccggtat tcgcccccca ggcatttctg
     2101 gtcctggccc atgtggcctt acgtcgtgga actccggccc aggccgcgat tcatctgaag
     2161 gcgttggaag gggagggcct gcagcattcc tccagcccct ggcaggccga gtatctcttg
     2221 ctgcaggcac agctggccga ggtgaacgac ggccctgcag cggcactgga ggtgttgacc
     2281 gagaccgggg cgcagcccat cacacctcgt gagatcgtct tggaggatcc ggcagtcgcg
     2341 gcctggtggg tacgttgcgc actcacggca gaccagcccg agatcgcggg aggggtggtc
     2401 gacaccatcg aggacctcag caagctcaac ccggaggttc ccgcgctgtt cgctgcggcc
     2461 acacacgcac gggcgctcgc cgaggcggac accgacgccc tcgccgaggc cggccgacta
     2521 caccgaaatc cctgggcccg ggccgcaaca gccgaggacc gtgcccggat ctttcttttc
     2581 cgtggtgacc acgagtccgc cattaccgag ctggactgtg ccatgaacgc ctacaaccag
     2641 ctcggagcgg aacgagaggc cgctcgcgtg cgcgcccagc tacgtggact cggagtgtgg
     2701 cgtcgacact ggaagcaggc aaaacgtcca ctgtcgggct gggagagtct caccgagacc
     2761 gaacggaagg ttgccaagct cgtggccaac ggactcacca accagcaggc cgccgaccac
     2821 ctgttcatct caccgcacac ggtcggattt cacctgcgcc aaatctaccg caaactcggt
     2881 attcgatccc gctcagcgct gatccgatat gacgcatcac gcgtatcgcg ccccgaagcg
     2941 tcgtagtttc ggtggggttc ccaggtgctg agccgtacgg gatgaccctg cagctcggga
     3001 ggggggtgcg gggcaggttc ccccgtcctg accagctgcg aatccgtgtc gggtcggagg
     3061 acccccgcgg gtgaacgagg gatcgccacg cgtcagacct ggaggatcct gtccgacttt
     3121 gccgctgcac gagccgaacc accatggtcg tgcagcctgc cctcgttcct acccgcgtcg
     3181 aggccatgac cacgcgggat gacgttgccc cggggtgcgc acggctcagg ctgaccttcc
     3241 cgggccgcgc gcaccgactc aggagagcac ggcgggcagg acgctcatcc ggcggatcat
     3301 ccactctgac tcccactgga cggcggtctc ggcgctcaac cgggcctgcg ggaaccgtcg
     3361 caggaagcca cgcaccgcaa tctgcgcctc gagccggacc agtggggcgc cgatgcagta
     3421 gtgcatgccg agcccgaagg acaggtggcc gtgcccccgt cgctccgcat cgaagctgtc
     3481 ggcaccctcg cccggcttcc gattcgccgc cgcgatgctg acctgcacgg gggcaccctt
     3541 ggggatcagg tagccgccaa gctcaatgtc ctccagggga aagcgccagg tcgggtgcgg
     3601 aaacggcggg tgcacccgca gggtttcctc gatccaagcc gtgatgtcct cgtcagtttt
     3661 cggtcgctcg tgcggtggtc ggcggatggc ctcgtacagc gaagtggaga tcagactccc
     3721 cgtggtttcg tagcccgtga tgatcatgcc tagggtccag acgatgacct cgccctcggt
     3781 gaccgcggca tccggcccat cagaggcggc cagtagcccg gtgatcacac cgtcgcgcag
     3841 gtcggccggg ttgcgcaccc agtcctcgac cgccccgaac agccctccga tcgcctcccg
     3901 gcgggcagcg tagtcggatg agtacagcat gatgtcagtg atgccgcgta gccggtgctc
     3961 cgcctccggg ggcaggccga gcatctcgga gatgaacgcc agcgggatct tgtgggtgta
     4021 gttcgtgacc acgttgacct cggcgctgcc gcctgaaccc gcctggctga gctcgtcgag
     4081 gaatccctcg accttgtcgg cgacccgctc gccccatcgc tcggtgttac gtgggctcag
     4141 taccggcgcg tggatccgtc ggatccgggc gtggttctca ccgtcactca tgatcatcgc
     4201 ccgtgcgtac tccgggtccg gctgtgctgt caccatcagt cccggctggc gcatccactc
     4261 tgggacaagg gcgatgtcct ttcccatctt ggggtgcgtg agcgcctgct tcaccagctc
     4321 gcggtcgcac acgacccacg catgcctacc caggtaggga attcgtacga ccggcgcgac
     4381 ccgggcggcc gcgatcagat ccggcatgca gtcgaacagc cctgggtcga ccggcatgtt
     4441 cgtctccggg gcttcggtca attcggtgtt cgtggtggta ctcattgggt gggacctccg
     4501 gtagggactc ggccctggga ttcggccatg gcctcgatga gctcggcggc tcgtcgcggg
     4561 gcgtcgtagc gctggtgctc gcgggacagc acgtgtgccc gttgccggta gcgctcgtcg
     4621 tgcagaacgg tgactacggc gttacgcagg gtggcctctg acaccgcgcg ccgggcgaga
     4681 acgacgcccg ctccggacca cgcgatccgg gccgcgacgt cgggattctc ctcggtcgcc
     4741 ggagcggcga ccaggggtac gccatgggcg agggcggcgt tgacaccgtt gtagccgccg
     4801 ttggtcagca tcacgtccac gcggggcaac agatggtgat aggaaacgaa ccgctccaac
     4861 cggacgttgc cgggtagcgg ccgtagcagg tcgacatcca ggtcgcttcc cgtggtcacc
     4921 acgacgagca ggtcctcgcg ggccagcgcc cggactgcgg gaacgagtag ccggtcgacg
     4981 tcgttggcgg tggtgccctg ggtgatgagc accaccggct tgtctccatc caactcctgc
     5041 caccaactgg gcggctcgaa ccgctccggg ggaagtccga agagaccgcc gatgaagtgt
     5101 gtgcctggta ggagatcgct gcgggagaac tcgaaggacg gcacggtgct caccaggtac
     5161 aaatctgggg ggcgcgtgat gttctccatg gcccgtgtcc tcagccgcgg caggttcacc
     5221 gaggctcgcg tgcggtcggc ctcccggcgt aggtctcgca tggacacatg gtcaccgagg
     5281 aatcgcagca gagcgttacg ggcccgtccc agcggcgacg aactcggttg cagccccaac
     5341 ccgagcggtg cggtatccct actgcccagg atgtagatcg aattgctcag ccaggccatc
     5401 ggcaggccgg ttcgctcgct cgcgaaacac gcgccataac acatgtcatc ggcgaggatg
     5461 cagtcggcgg gaaagcgttc gagcacgcga agtaggtcgt cgagctggcc gggcgccgtg
     5521 tggtagaaga tgtcacgcac gccgatcttg aaactggcga ggccggtcag cccggcgtgg
     5581 ctgggaaacg cctcctcccg actcctgccg ccgaagtcga gtgcctcact catcggctcg
     5641 aagcgcgccc cggcctgctc gacctgctcc tgaaaggcac ggccggtgta ccaccgcacc
     5701 tcatgtccac gccgagtcag ttcgcccgcc acatccacca tgctgacgac gtgtccgggt
     5761 gccggtgtgg tagcgatcaa cactcgcatc aacatcgcct ccgtcaggct tcggttcacc
     5821 gctcgccagt gtcaccgaat gccgagtcgt gagcaccatc tcggggcgaa tcccacgcgt
     5881 ccacgtagga tggcagcact ctctggccgg ggcaggcgca ccgcttcgct gggcaaacca
     5941 cctgtggtca ccctcatcgc gtgatgtgca gacgatggca ttggcggaac gattgccgaa
     6001 ggtcgatctc gtcatcgccc ttcgagcaca ctccctgtgc tatgtgcacc gcgttgagag
     6061 gacacctgtg gtggcagcct tgcgaaacag tggcgggtca gaatccgcca tcaatgggca
     6121 gaagcgggtc actgtgatcg gcgcgggcat cgccgggctg gtgacggctt acgagctgga
     6181 acgtctcgga caccgtgtcg agatcatcga ggcgagcccg gatgtcggtg gccgaatcga
     6241 cacgcaccgg ttcgccgtcg acggccggcc cggtcccttc gccgaactcg gtgcgatgcg
     6301 gatccccgca gggcataggc tgaccaggca ctacatcgcc gagctcggtc tccaggacca
     6361 ggttcatcgg tttcagacgc tcttctccga tgaccacgcc tacctgccca gttcaggtgg
     6421 atacgtccgg gtcggtgacg cgcacgaaac gctggtcaag gagtttgtcg ctgggctgcc
     6481 gaaccggcag taccgggaga acaccctgct ctttggtgcc tggctggatg ccaccatcag
     6541 ggctgtcgct ccgcgtcagt tctacgacgg aatgcacaac gagatcggtg cggagctcct
     6601 cgacctcatc gatggcatcg atctgacacc gtaccggtgc gggagctcgg gcaaccggat
     6661 cgacctgcac gccttctacg ctgaccaccc gttgatccgg tcgctctgcc cgccgcacct
     6721 ggaacggttc ctcgacgacg tactcgacga gaccggttcc aacatcatcc gactacgatc
     6781 cgggatggac atgttgccgc ggcggctcgc cgcccagatc cgcggaccga tctcgaccgg
     6841 ccgcgaggtg gtgggcatcg agatccagca ggactctgtg ctcctccacg tccggcacgg
     6901 tgcgaagacc atcgcgacga gctgcgacta tgtggtgtgc accattccgt tcacggtgct
     6961 tagggcaatg cggttggtgg gattcgacca ggacaagctc gacatcgtcc accagacgaa
     7021 gtactggccg gcgacaaagg tcgccctgca ctgccgtgaa gcgttctgga agaaggacgg
     7081 gatcagcggt ggtgcctcct tcaccggcca gcacgtacgg cagacctact acccgcccgt
     7141 cgacggtgat ccggcactcg gggccgtact gctcgcgagc tacagcatcg ggcccgacgc
     7201 ggaggcactc ggccgcctga gcgaggcgga gcgaaatgcg ctgatcatca gggaactgag
     7261 cgagatgcac cccgaactgc gtgcacccgg catgatcctc ggcgtggcga gtcgggcctg
     7321 gggccggcac cggtggtcgc tcggggccgc caccgttcga tggggacagg gggccgcact
     7381 ccgcgaatcg gagcggcgag aggcggtgcg gccgcagcgg cgactgttct tcgcgggtga
     7441 acactgttcg tcgaagcccg cctggatcga gggtgcgatc gaatcggcca tcgatgccgc
     7501 ccacgagatc gaatggcatg agctccgagc cgaccgtgag ttcgccacca cccggtcgag
     7561 ccgcctgggg aaactggcat gagcgtcttc gacctaccac ggctgcactt ccgtggatcg
     7621 gcgacgacgc acctgcccac cgggccacgc aacggcctgg tggacctggc gacgaacacg
     7681 gcgctcaccg aggacggcag ggcctttccc gtagcgagtc cggctcacgc ctaccacgac
     7741 tacctcgacc aggtgggacc acgcttcgac ctcgccgggc gtccctgcgc cgacggaccc
     7801 ttcagcgtgg ccaagggcag ggacttcgcc ggcaacggac acttttcggt ggacgcgcgg
     7861 atcgtcagcg tcgaggtccg cacgagcgag atcaacaccg tggacccggt ggtcggacgc
     7921 accgttgaca tgtgggggca ctacaacgag tacctcggca cgacggtgaa ccgggcccgg
     7981 gtcttcgatg tcgacccggc ctccaaccgg accacgacgc tgatggtcgg gcagtttggc
     8041 ttcgggcgcg acgggcggtc ccacgacgtc ggctacctcg ccaccggccg cgtccacggg
     8101 ttcgtgccgc cacggtggca caacgcggac cacgccgtcg acatcgacga ccactggcag
     8161 gccaacgacc tgcgccggtc cgtcgtgcac cagttcgtgg tgacggcgga cgaactgacc
     8221 tggctcgacg agccggcagc ctccccggcc gtacgtctgc tcagggacac cgacgcaagc
     8281 ggcctggtgg tgcagttctc gctcagccgc atgtccgtcc cgtccgcgcc cgaccagccg
     8341 agccggtggc agctcaacgg gacgatcgcc ccctggtacc cgcacgaacc gcgcacctac
     8401 ccggcgggtc gcctactcgt cccggacagc cgaggtccga gccgcaccga cggccggctg
     8461 cacaacctct cggtcgagct gaccgacacc cacgccatcc tcaatatgat cacggcggtg
     8521 cccaccgtag ggaccgggcc ggtcgatgtc ggagatctcg aactgcgtac cgccggcgac
     8581 ggtcgactgg tggcccgcct gccccgggag gcgtatctcg ggcaggagta cctcctggcc
     8641 tgcggcctgg tgaccgttcc catcgagatg tccgccgagg ccgcctccga ggagccgttg
     8701 agcctggttt cccgtagacc cggcggaccg gtgcgacagc tacgggaacg agaggtcaac
     8761 gtacaggtcg acgaatctgc gctcatcctc gagcacccac gagacgccga ggacgcgcac
     8821 cacgacgttg aggttcccgt gcgggccttc gtccggggcc gcccgggtgc cgtccacgag
     8881 atcgcggtac ggcagttctt caatccccgg gctctgccag gtgaggctgc ggcccgttcc
     8941 cccaaggccc gctgctccga catcgacgtg ctcaggctgc gtccgggacg gctggacgag
     9001 gccggaggct ggtcgagcgc ctgcgttctg ggtaccgacc aggcggggtg tggatggttc
     9061 accatgcggg gtgcgacggc cggtacggcc ctggtcctgc tgtccaccga cgccgacgac
     9121 ctgccctgcg atccggaggc acccggatcc gccacgctgg cctacgacca cgacgacgtg
     9181 ctcggatact ggcctggcgc aggctacctg tcgatccgtg tcctacccga cgactggcgg
     9241 ctggccgggc tcgagcagaa ggacgtgacg ttcgagctgg tctaccggga ggtttttgcc
     9301 ttctacgagc atctgttctc cttcatgaag gcagaggtct tcagcctggc ggaccggtgc
     9361 aaggtggaga cgtacgcaaa gttgatctgg cagatgtgcg atccccgcaa caaggccaag
     9421 acctactaca tgccgccgac gcgagacctg tccgagccga aggcccggct cctcctaaag
     9481 tacctacgcg cgcagcaggt accggatgcg gtcctcctga cggcgccggc cacgaatcgc
     9541 cgtagccgca ggatagccac acgtgatcaa ctcgtccgcg tgctgcgtga ggcggcaaag
     9601 gtcgagttgg ccgtcatgct ccagtacctg tacgcagcct attccgtgcc cgcctacggt
     9661 gtcgggctgg agtacgtgcg gcagggtggg tggacgcgcg agcagttgcg gctggcctgt
     9721 ggtgacggtg gtgaaaccct cgacgagggt gttcgcagca tgctgctgaa catcgcccgc
     9781 gaggaaatga tccactttct tctggtcaac aacatcctcg tcgcgatggg tgagcccttc
     9841 cacgtgccgt ggattgactt cgccacgatc aaccacgagc tcccagtacc gctggacttc
     9901 tgcctcgaag gcatgggaat cggtagcgtg gagcgtttca ccatgatcga acggcccgaa
     9961 agccacgtac ccgacgtgct gggaactggt ggcgcgacgg cccaggacga cggacacacc
    10021 tacgcctcgc tgagcgacct gtactccgca atccgggagg gcctgcagca catccccggc
    10081 ctctttctgg tcgacaaggg tcggggaggc ggtgaacacc acctcttcct gcgggagtca
    10141 atcaacagtc gccaccccga ctaccagctt gaggtcgacg atctgtcgag cgccctgttc
    10201 gcgatcgacg tcatcaccga gcaaggggag ggcggagtac tcaccgccgg acctgacgag
    10261 gtgtcgcact acacctcgtt cctgcggatc ggcgaactcc tccgtggcgc agtggccccg
    10321 ggcggggatc cgtggcaccc ggcctatccc gtgctgcgca acccgacgct tcggcatggc
    10381 gaacgggcca tggagacagt caccgatcca gatgcccgaa cggtcatggc gctgttcaac
    10441 cgcgcgtact tcatggcact tcagctcatg gcgcaacact tcggtgaacg ccccgacggg
    10501 agcctgcggc ggtccgacct gatgaacggg gcgatcgaca tgatgacggg tctgatgcgc
    10561 ccgcttgctg aactgctggt gaccatgccg tcgggacggc gtggcaggac cgctggaccg
    10621 tcgttcgaac tggtggagca gcccaccccg gtgtcccgcc ccgaggtggc ccggcggggc
    10681 atcgccctgc gtctcgacga cctcgcggca gagtgcggca agtccgccct ggtgccgacc
    10741 cgggtgggcg agatgagcgc gttctgggcc gaccacttcc ggccgtgacg gtgacagggc
    10801 ttcccgtggt gcccgagcgg caaccccggg acgactttcg ggaaggagag agtatgccat
    10861 ccgcgacgtt gccgcggttc gccctgaccg gctggagcag ggagaacatc gtcaatccct
    10921 acccggtgta ccagcgctac cgggaggtcg cttcggtgca ccggggcgaa ccaggcggcg
    10981 acgccccgga caccttctac gtgttctcct acgacgaggt tgtccaggtg ctgtcgagta
    11041 actgtttcgg tagggggagg tccctcgacg ccgcgaaggc atcggtcccg gtaccggccg
    11101 agcagaaggc cctccgggca atcgtcgaga actggctggt gttcatggac ccgccacgcc
    11161 acaccgaact acgctcgcta ctcaaccgga gcttttctcc ccggatcgtg accgaactgc
    11221 ggccccgcat cgcgcggatc gcacaggaac tcctgtcccg gctcggccag caggtggacg
    11281 tcgatctcgt cgagagcttc gccgcgccgt tgcccatcct tgtcatctcc gagctgctgg
    11341 ggattccgga ggagcgtcgc gcatggttgc gtgccaacgc gttggcgctg caggaagcca
    11401 gttcctcccg tgcgggtcgg gacgtggatg gctacgcaca ggccgaagtg gccgcgcagg
    11461 agttcaccga gtacttccgg gagcaggtgc ggctacggcg gggtcgtgcc ggtggagatc
    11521 tgatcacgat cctcgccaac gcacaggagc gcggtgcacc agtgagtctg gacgcgatcg
    11581 tggggacctg cgtccacctc ctgaccgccg ggcacgagac caccaccaat tcgctggcga
    11641 aggccgtgct tgcgctgcgg gaacatccgg cggtactcga cgagctccgc ggcgccgagg
    11701 ggctgacgac ggatgcggtc gaggagttcc tgcgctatga cccgcccgtg caggccgtga
    11761 cccgatgggc gcaccaggac accaccctcg gcgggtgtga cataccacgc ggcagccgag
    11821 tggtcgcgct gctgggctcg gcgaatcggg atccggcacg cttcccgtca cctgatgtcc
    11881 tggacgtacg tcgccctgcc gaccggcacc tcagtttcgg tctgggtatc cactactgcc
    11941 tcggcgcgac gctggcccgc gccgagctcg agatcgggct ccaggcactg ctggacggtg
    12001 ttcccacgct gggctacggc acccagcacg tcgactacgc cgacgacctg gtcttccacg
    12061 gaccgagccg gctggtactc gtcaacctag gagaaaggtg taaataatgt ccaaagtgtc
    12121 atctcagccc gtaccgaaag cggtcggcga gctgtacgac cgtctcaccc tgagcgcaat
    12181 gaccgacggt acgttcaacc cgaacgtaca cattggatac tgggactcgc cggagtcgac
    12241 ggcgtcggtc gacgaggcga tggaccggct gaccgacgtg ttcatcgagc gtttgaaggt
    12301 cggcgcgtcg aaccacgttc tcgatctggg ctgcggggtt ggcgggcccg gcctgcgagt
    12361 ggtggcgcaa accggcgcac gtgtcacggg catcagcatc agcgaggagc aggtcaaaag
    12421 cgccaaccgg ctagcggccg aggcgggagt cgccgaccgc gccgtgttcc agcacggcga
    12481 cgcgatgcga ctcccgttcc cggaccattc gttcgacgcg gtgatggctc tggagtcgat
    12541 gtgccacatg ccggaccggc agcaggtgct caccgaagtg tgccgggtgc tcgtcccggg
    12601 tggccggctc gttctgacgg acgtgttcga gcgcttcccg cgtaaggaag tccggcacca
    12661 gggcattgac aagttctgca acgatctcat gtccaccacg gcggacctcg acgactacgt
    12721 cgccatgctg caccgttccg gtctgcggat gcgcgagctg ctcgacgtga ccgaacagac
    12781 cacgctgcgc ctggcgtacg agttggccaa actgcccgtc ctccaggaac gccccgcggc
    12841 cctgaacgaa ggcaacttcg agttctccga cgacgctttc aaaccgtccg acctggaagg
    12901 cgttgacgac ttcggctgcc tcctggcaac ggcggaacgc ccgtagcaca ctccggcgcc
    12961 ggggagcgtc gtaccacgct ccccggcacc cgctgggctg tccgatctcc ggcaacgagg
    13021 gaaagacggg acgacatgac aaactccggc gagtggaccg acgtgctgat cgtgggcggc
    13081 ggcccggtcg ggatggcgtt ggcactggac ctgaggtacc gcggaatcga ctgcatggtt
    13141 gtcgaagcgg gcgacggcga ggtccggcac cccaaggtga gtacgatcgg cccgcgctcg
    13201 atggagctgt ttcgccgttg gggtctcgcg gacaccatcc gtaacgcggg atggcccgcc
    13261 gaccatcccc tggacatcgc ctgggtcacc agagtcggtg gccacgaggt gcaccggtat
    13321 cggcggggca cgacggcgaa ccgtgggccc tacgtacaca cccctgagcc cgaccagatc
    13381 tgtccggcgc actggctgaa tccactgttg caacgggccg tcggcgtgca ccccaccggt
    13441 ccactgcggc tcaggacgac cgtggaccgc gtgcgtcagg cggccgacca tgtcgaggcc
    13501 accctcgtcg aggacggttc cggaaggacc ggcaccgtcc gcgcacaatt cctggttgcc
    13561 tgcgacgggg ctgcctcacc cattcggcag gcctgcggca tcgacgcacc gccacgccac
    13621 acgacgcagg tctttcggaa catcctcttc cgtgccccgg aactcaagcg gcaactcggt
    13681 gaccgcgtcg cccttgtcta cttccttgtg cggtcatcca cattgcgctt ccccatgcgc
    13741 tcgctcaacg gcagtgacct ctacaacctg gtcgttggtg tggacgctgc cgctcaggtg
    13801 gatggcaggt cgttgatcac cgatgccatc gccttcgaca caccagtgga gctgctcagc
    13861 gacagccagt ggcatctcac gcaccgggtg gccgacagct accgagcggg acgggtcttc
    13921 ctcgcgggtg acgccgccca cacactctcg ccctctggtg gcttcgggct caacaccgga
    13981 ttcggcgatg tcgccgatct gggctggaag ctcgccgccg cactgaacgg ctgggcgggg
    14041 tgccacctgc tggacacgta cgaagccgag cgcaggccga tcgccctgga gagcctgcag
    14101 gaggcgaacc tcaacctgca acgcaccatg cgccggcacg ttccggccga gatccacgcg
    14161 gacggtccgg cgggtgaaca ggctcgcgcg gaaatggccg agcagctggt gcgcggcgga
    14221 gcgcatcgcg agttcgacgc acctgagatt cacttcgggc tgtcctaccg atccccggcc
    14281 gttatctctg acccactggt cccaccccgt cagggccagc cggatgccgc ctggcgcccg
    14341 ggcagcgatc ccggctaccg cgccgcgcat gcctggtggg ataccgagac ctccacactc
    14401 gacctgttcg gtcacggctt cgtcctgctg tcctttaccg agggggcaga cgtgtctgcc
    14461 gtggagcggg cattcgccaa acgagccgta ccgctgaccg ttcgacgcgg gagcgacccg
    14521 gagatagcca agctctacga gcgttctctc gtgctggttc gtcccgatgg ccatgtggcc
    14581 tggcgaggcg acgaactgcc cgctgatctg gggaagttcg tcgacacgat ccgaggcgaa
    14641 tattgacgtg caacctggtc ggaattctcg gcaatggcct gaccaggaaa ccgtgacgcc
    14701 catcgcggag gtgggggcac tggaagaggg gcttccagta gcgccggcca cgttccggat
    14761 gctgttccga tatggggagg gcgaatacat ggaggtggtg gtgtgaaagg aatagttctg
    14821 gccggtgggt atggtacccg gctgcatccg atcactctgg gtgtgtcgaa gcatctcctt
    14881 ccggtctacg acaagccaat gatctactac cccctgtccg ttctcatgtt ggctggaatc
    14941 actgatataa aaatcatctc atcgccagac gaccttccgc tgttccagcg attgttgcgt
    15001 gacggttccc agttcgggct gtcgctgagc tacgccgagc aggacaagcc tcgtgggttg
    15061 gccgatgcct tccgaatcgg cgccgaccac atcggcgacg actcggtcgc actcgtgttg
    15121 ggtgacaaca tcttccacgg cccgggcttc agtgacctgc tgcagcgcag tgtggtcgac
    15181 atcgacggct gcgttctgtt cggctatccc gtgcgtgacc cggagcgcta cggagtgggt
    15241 gaggtggacg cacggggacg actcgtcgag cttgtggaaa agcccgccca gccacgctcc
    15301 aacctggcca tcacagggct ctacctctac gacaacgagg tggtcgagat cgcccgtgat
    15361 ctccaaccgt ccgcccgtgg tgagctcgag atcaccgatg tcaatcgcgt ctacctccag
    15421 cgaggcaagg ccgagctggt ctcactgggg cgtggcttcg tgtggctgga taccggaaca
    15481 cacgacgcgc tgaccgaggc aagccagtat gtgcagatca tggagcatcg ccaaggcgtc
    15541 cgggtcgcct gtctggagga aattgcctgg cggatgggct ttatcgacca ggaggcctgc
    15601 catcgtctcg gtcgccagct cgcgaagtcg ccctatggac agtacgtgat ggaggtgacc
    15661 gcggctgccg gagggccggt cgccgtcacc aactggcctg ccacagtgcg tagggggcga
    15721 cagtgaggat cctggtcacc ggcggtgccg gctttatcgg ctcacactat gtccggtccc
    15781 tgttggctgg tgagtacgct gcggaggacg ctgtcggagc ggtggacgcc tccgtcactg
    15841 tcctggacaa actcacctac gccggcaatc gcgccaacct gccggccacc cacccacgcc
    15901 tgaccttcgt gcagggtgac atctgcgacc agggactgct gcgggacctg ttcaagggcc
    15961 atgacgcgat tctgcacttc gccgctgagt cacacgtgga tcggtcggtc gacggtggag
    16021 caaccttcgt acgcaccaat gcgttgggaa cccagtcggt gctggaagcc gctgtcgcgg
    16081 tcggcgtacc gcgggtcgta cacgtctcga ccgacgaggt ctatggctcc atcgaacacg
    16141 gggcgtggac cgagacgtgg ccgctgctgc cgaactcccc gtatgcggct tccaaggcga
    16201 gcgcggacct catcgcccgt tcctactggc gaacccatgg cctggacgtt tcgatcaccc
    16261 gctgttccaa caactacggg ccctaccagc atccggaaaa gctcgtcccg ctgttcatca
    16321 ccaacctgct cgagggattg ccggtgcccg tgtacggcac cggggtgaac gtgcgggagt
    16381 ggctgcacgt ggccgaccac tgccgcgcac tccaccgggt actcacccga gggcgtcccg
    16441 gtgaggtcta caacgtgggc agcggaaacg agttgacgaa cctggagctg accgagcgcc
    16501 tgctccacct gtgcggcgcg gaccgctcca tgatccgtta cgtcaccgac cgcaaggggc
    16561 acgaccagcg gtactccctt gacgacacca agatccgcga gtgtctcggt taccggcccc
    16621 gcgtctcctt cgccgatggg ctggccgaaa ccgtcgcctg gtaccgcgac aacccacagt
    16681 ggtggaaggc ggccaggcac ggcgctccca agaccaccga ggccgcgcct cgggcgacca
    16741 ccggagtggt ccgtggaacg cacaaccgta tcgacgacca ggagccacca aaatgacgac
    16801 ccatgtgtgg gactacctac cggaatacgc caaggaaaag gacgacatcc tggacgcggt
    16861 gcaaaccgtg ttcggctccg ggcagttggt gctcggcgaa agcgtccgcg gcttcgagcg
    16921 ggagttcgcg gcctaccact cgctgccgta cgccaccggg gtcgacaacg gtaccaacgc
    16981 gttgaagctg ggcctggagg cgcttggtgt cgggcctggt gacgaggtca tcacggtctc
    17041 caacacggcg gcccccaccg tggtcgccat cgcgggggcc ggagcgacgc cggtcttcgt
    17101 cgacgtccgt gaggacgact tcctcatgga caccgatcag gtcgcggccg ccatcacgcc
    17161 ccggacccgc gcgattctgc cggtgcacct ctacggccag tgcgtcgaca tggcgccact
    17221 tggccggctc gccgaggagc acggcctgag gatcctggag gactgcgcgc agtcgcacgg
    17281 ggcgcgccac cacggacgcc tcgcgggcac catgggcgac gcggccgcgt tctccttcta
    17341 tcccaccaag gtcctcggcg cgtacggcga cggcggtgcg gtgatcaccg ccgacgagtc
    17401 gatcgaccgt cacctccggc agctgcggta ctacggcatg gacaaggtct actacgttgt
    17461 tcgtacgccg gggcacaact cgcgccttga cgaggtgcag gcggagatcc tgcgacgcaa
    17521 gcttcgccgg ttggacgagt acgtggccgg gcgcaacgcg gtcgcccggc ggtgggagca
    17581 actgctcggc gacctttccg gccccggtgg actgcggctg cctaccacca acccgggcaa
    17641 cacccacgtc cactacgtct acgtggtccg ccatccccag cgagacgcga tcatccaggc
    17701 gctgcgggcg cacgacatct cgctcaacat cagctacccg tggccggtac acaccatgga
    17761 cggcttcgcg catctcggct acaccgaggg ctcgctgccg gtgaccgagc ggctggccag
    17821 ggagatcttc tcactgccca tgtacccgtc cctgccggag tcggagcagg agcgggtggc
    17881 agcggccctg cgcgaggtgt tggccggact gtgagcccgc actggaaccc ggaaccaaga
    17941 accagcagcg acagccgttc ccggaaggag atctcctgat gtcggaggac agttccacga
    18001 gcagtgggca tcgacatgat gacgtccacg gagtgacggt gcgtcgactc gccatcgacg
    18061 gtgccgtcga attcacgccc tccgtccacc gggacgagcg agggttgttc gcgtcgccct
    18121 accaggagcc ggccttcacc gcgacgttcg gctggccgct gttcccggta cgcgacctca
    18181 gtcacaacgt gtcggcccgt ggcgtgctgc ggggtatcca cttcacctcc acgccaccgg
    18241 ggcgagcgaa gtacgtctac tgcccgtacg gcaaggtgca ggactttctc atcgacctga
    18301 gggtcggctc gcccaccttc ggctgctggg acagcaccga actcggcggt gacacctgcc
    18361 gggcgatcta catcccggtg ggggtcggcc acgccttcct gtcgttggtg gacgactcca
    18421 tgatcgtgta cgccatgtcc aagggctacg ttgcggagga cgagttggcc atctcgccgc
    18481 tcgacccggc actgggactg ccgctgcccg ccgggatcac tccgttgcag tccgaccggg
    18541 accgggccgc ccccacgctg gccgaggcgc tggatcgtgg cctgctgagc gacgacgcgg
    18601 tgtgccggga cgtggaggcg aagctatggc agtgaagcgt cccctcgttg tgctgctcgg
    18661 tgcgaccggc ttcgtcggct ccgccgtgct acgcgagctc gccgtgcgtg acgttcgggt
    18721 gcgggccgtc tcgcgcggcg cggcctcggt ccccgaggac gcccgcgccg agatcgaggt
    18781 gcacaccgcc gacctcaccg agcctggccg cctggcccag gccattgccg gtgccgacgt
    18841 cgtcatccac accatcgcct acatcgccgg ctcgacgacc tggcgtatca acgaaggtga
    18901 ctcggctgcc gagcgcgtca atgtcggtct ggtccgcgac ctggtcgcgg tgctgcggga
    18961 cggcgaccgg aacctcccgc ccctgcccgt ggtcttcgcg ggcgccgtct cgcaggtcgg
    19021 gcccactgac aaggaggtgc tcgacggcag cgagcccgac tggccccagg gcgagtacga
    19081 ccggcagaag ctcgccgccg aacgggtgct gctcgacgcg cacgcggaga ggatcctgcg
    19141 agctgtgtcg atccggcttc ccacggtgtt cgggtacggc ccacgttcca ccgcccggga
    19201 caagggtgtg gtgtccacca tggtgcgtcg ggccctggcc ggggaaccga tcaccatgtg
    19261 gcacgacggt acggtgcgcc gggacctgct ctacgtcgag gacgtggcgc gggcgcttgt
    19321 cgcggcggtc gaccacgttg acgccctggc cgggcggccg tggctactcg gatccgggcg
    19381 tgggctgccc ctgggcgagg tgttcaccac ggtggcgagt ctggtcgccg aacgtaccgg
    19441 caagccgcct gtgcgggtcg tctcggtgcc cccacccgag cacgccgagc caggtgactt
    19501 ccacaacatc acgatcgacg cgaccccgtt ccggtcggtc agcggctggc gcccgaaggt
    19561 accgctgacc gatgcgctgc gtcacacggt cgacttctgt gccagtggtg ccgaggaggg
    19621 cctgtcgtga cccggcgccg cgccggtagc cctcgggtgg cccggcggtc aggcaggcga
    19681 cagccccgtg tccaggtcat ccgatgaccg cgccgaccgt gctgcgccta cgcgccgacg
    19741 acacgctggc ccaacggttg gctcgctcgg cggccctgcg ggccgagggc ttcgcgctgc
    19801 gtacggccga cgtcgccgga tggctcaccc agcgggctcg ggcgcaccac ttccgagttg
    19861 agcggattgc gctgaacgat ctggatgggt ggttcttcgc gactgatacc ggcaacctgc
    19921 accaccacac cggccggttc ttctcaatcg agggtatcga cgtcaatcac aacgaggggg
    19981 caattcgccg gtggcagcag ccgatgatcc gccagcctga ggtgggcatc ctgggtattc
    20041 tggccaagga gttcgacggt gtgctgcact tcctcctcca ggcgaagatg gaacccggca
    20101 accgcaatct cctgcagttg tcaccgacgg ttcaggccac ccacagtaac tacaccggcg
    20161 cgcaccgggg gacgccggtg aagtacctgg agtacttcac cgatcccagc cgcgggactg
    20221 ttctgaccga cgtcctccag tcggagcacg gttcctggtt ctatcggaag tccaaccgca
    20281 acatcgtgat ggagacggtg gacgacgtgc cggtggatga cgacttctgc tggctgactc
    20341 tcgggcagat cggtgagctg ctgcggtacg acaacgtcgt caacatggac gcccggacgg
    20401 tcctggccag ttgtccggtg acctcggccg agcctggcgc cctgaatacc gacatggagc
    20461 tacggtcctg gttcactgtc gaacggtccc gccacagcct gaccgccgag cgggttccgc
    20521 tggccgacat cgaagagtgg aagcgtagcg acttcactct cggccgggat gacggccgct
    20581 atttccgtct ggtcgccgtc gcggttgagg cgggcaaccg tgaggtcacc ggctggtcgc
    20641 agccgctgtt cgagccgacg ggcatcggtg tgagcgcctt cctgttccgt catttcgggg
    20701 gcgtaccgca cctgttggtg caggcgaagg tggaggccgg gttcctggac accgtcgaac
    20761 tggcaccgac ggtgcagtgc acgccgggta actgggcgca cctgccggag ccgctgcgcc
    20821 cgtacttcct cgatgtcgtc cgggtcgcgg gccccgaccg tgtgcgctac gcggcggtgc
    20881 actccgagga gggcggcagg ttcctcaacg ccgagagccg gtacctgttc gtcgaggccg
    20941 acgaggcgca ggcgcccctc gacccgccca ccgggtttcg ctgggcaacc ccggggcagc
    21001 tcaacaatct ggcccagcac ggccactacc tcaacgtcca ggcccgcacc ctgctcgcct
    21061 gcctcaacgc cggtacggtg cgtctggatc cgaccaggtg acgcggcgcg ccggcctgtg
    21121 gcgggcggag gactcacctt gacatgatca tcggtcgtaa gccgctcctt tccggcggct
    21181 taacgctccg gctctcccga ggaggtaccg agactccccg ggtgagccgt tgcgaatgcc
    21241 agcgccggga cgcgacagcg gcgtagggtg tgctcggcga gtctgttgtt gcctgcggcg
    21301 accgaattgt tgacgtgggg cctcggccgt tggcatccaa ctctgggagc atgcatgccg
    21361 aacacccggc gaagtatcga ctccttcggt cctggcgtgg tcggactgaa cccgatgttc
    21421 gcgcgtccgg gtgaggcgac tgagcttgcc cgattctcga ttccggacga cgagtcgcta
    21481 ccggaaaccg cataccagat cgtgcacgac gaggtggccc tcgacgggaa cgcacggctc
    21541 aacctcgcca cgttcgtcgg cacctggatg gacagccatg ccgagaagtt gttcgccgag
    21601 acgttcgaca agaatctgat cgacaaggac gagtatcagg ctaccgacgt cattgagacc
    21661 cggtgccgga ccatcctggc ggatctctgg cacgcgcccg agccccggaa cgccgtcggc
    21721 acgtccacga tcggttcgtc cgaggcgtgc atgctgggtg gtctggcgct caagcgacgc
    21781 tggcagcacg cgcgtcgcag cgccggccag tccacggatc gccccaatct ggtgatgtcg
    21841 agcgcggtgc aggtgtgttg gaagaagttc tgcaactact gggacgtcga ggcccgaacc
    21901 gtgccgatct ccgaggagcg cagggtgctc gacggccacg accttcggtc gtatgtggac
    21961 gagaacacca tcggtgtcgt ggcgctcctg ggtgtgacgt acaccgggat gtacgagccg
    22021 gtcgaacgga tcgcggcggc actggacgat atccaggcgg cgaccggatg ggacatcccc
    22081 attcacgtcg acggagctac gggtgcattc atagcgccgt ttatccaacc tgacctggtc
    22141 tgggacttcc gtatcgggag ggtggcttcg atcaatgcat cgggacacaa gtacggcctg
    22201 gtctacccgg gcctggggtg gattgtctgg cgagatcagg tggcactgcc cgatgacctg
    22261 agattccggg tagcctacct ggggggcgat acaccaacgg tcgggttgag tttcacccgg
    22321 ccgggatccc atgtgctact gcagtactac ctcttcctgc gcctcggccg ggacggtttt
    22381 cggcgagtgc agcaggccac gcacgacgtc gcacagtacc tgtcccggga gatcgcagca
    22441 atgccgcagt tcgagttgtg gagtgatggc agcgacattc cggtgctgac gtggcatctc
    22501 cggaaggggc cttcctggaa ctggaacctg taccacctgt ccgatcgact gcgcatgaag
    22561 gggtggaagg ttcccacgta cccgatgccc gaggacctga cggacctcac cgtacaacgg
    22621 atcgtggtcc gtaacgggct cagtcgcgat ctcgccgggg tcttcatcgc cgacctccac
    22681 gcggaggtag cgtttctcga atcccttacc gttcctatca cgactttggg tcagcgaccc
    22741 gggttccatc attgacgggg ttgcgggaac gcgatggccc cgtcagcagc caggccgccg
    22801 gccaagaatt cggcaaagat caccgttctc gggctggcga tgctcaacat cgtcgcggtg
    22861 gtcagcctga gtggcctgcc tgctgaggcc gagtacgggt tgagtgcggc gttttactat
    22921 atctttgctg cgatcttctt tctcgtcccg gtctcactcg tcgccgccga acttgccacg
    22981 gcatggccgg agaagggtgg tgtcttccgg tgggccggag aggcgttcgg ggggcgttgg
    23041 ggatttgtgg ccatcttcct gctcatcgcc caggtgacga tctggtttcc ggtcgtcctc
    23101 accttcggcg cgatctccct ggcgtacacc ggcccgcagg cgactctcga ccagaagttg
    23161 tccggcaacc ggctctacat tctcctgacc gtgctcgcgg tgtactggat cgccaccgcg
    23221 atcggttccc gtgggatggc cgcattcacc cggatcgcga agtggggcgg catcgtcggc
    23281 accatcctgc ctgccgctgt cctcgtcacc ctcggtttcg cctacctgtc caccggtggg
    23341 cagtcgcaga tcccgctgcg ttggggtgat gtggtcccgg acttcagccg ggtgagtaac
    23401 ctcgtgctcg ccgcaagcat cttcctgttc tatgccggga tggagatgaa tgcgatccac
    23461 gtgcgggacg tgagaagtcc ctcccggcac tacccactgg cggtggggat cgcggccgtg
    23521 ggcacgatga gtatcctggt tctgggtacg ctggcgatcg cctttgtcgt tccgcagtcc
    23581 gatattgatc tgacacagtc cttgttgata acgttcatcg acgttttcca gtggttgggc
    23641 ctgtcctggg ctgcgcccgt ggtggcggtc gcgctcacga ttggcgtcct ggccggcatc
    23701 gtcacctggg tggtcggccc gtcgacggcc atgctcgccg tggccaaggc cggctaccta
    23761 ccgccgttct tccaggccac caacaagagc gggatgccca cccacatcct gctggttcag
    23821 gcagtcgcgg tgagtgtcct ggcggtgctg ttcgtcttca tgccgtcggt acaggcggct
    23881 ttccaagttc tcagccagct tgccgggctc ctctatctgg tcgtctacct ggctatgttc
    23941 gcctcagcga tctcgctgcg ctacagccag cccgatcggc gccggccata ccgggtgccg
    24001 ggtgggcttg cgggaatgtg ggtcatcggt ggagttggtt tcgttgcctc ggcgctcgca
    24061 ctcgcctcca gcctggtacc gccgagtcag atcggggtcg ggaacccatt tctgtacatc
    24121 ggcctgctcg tcgggctggc cggcctgatc gtcacggtcc cgctcgtcgt gtacgcccgg
    24181 cgcaagccgc actggcacga cccggccagt gacgtggcac cgttcgcctg ggaggcgcga
    24241 ggagcacgtt ccggcgccgc cgaaacgcgg gggcgacgga cgaacgacgc cgacgagtaa
//
