LOCUS       BGC0000832             32944 bp    DNA     linear   BCT 13-DEC-2002
DEFINITION  Streptomyces roseochromogenes subsp. oscitans clorobiocin
            biosynthetic gene cluster, complete sequence.
ACCESSION   BGC0000832
VERSION     BGC0000832
KEYWORDS    .
SOURCE      Streptomyces roseochromogenus subsp. oscitans DS 12.976
  ORGANISM  Streptomyces roseochromogenus subsp. oscitans DS 12.976
            Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
            Streptomyces.
COMMENT     ##antiSMASH-Data-START##
            Version      :: 6.2.0-924c3663(changed)
            Run date     :: 2022-11-07 20:45:21
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..654
                     /codon_start=1
                     /gene="cloE"
                     /gene_functions="biosynthetic (rule-based-clusters) other:
                     LmbU"
                     /gene_kind="biosynthetic"
                     /note="similar to novE of novobiocin biosynthetic gene
                     cluster"
                     /product="Regulatory protein CloE"
                     /protein_id="AAN65220.1"
                     /sec_met_domain="LmbU (E-value: 8.6e-85, bitscore: 274.3,
                     seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVASGQTASKAGGSGTTPVRPTAGEATPVDSKQSRHASYLGLEVS
                     AERTRLQIPRDLSLEAWCRLGGRILAVCDSSAWWIGDWLVFGQNQYGDRYRRAMKETKL
                     DYQTLRNYAWVARKFEPSRRRDGLTFQHHMEVAALSEAEQDHWLDFAVRLNWSRNELRK
                     QIRASMSGEEGDLRRQVQLSLQLDELRLERWREAARRSNLTLTDWISSVVDEAI"
     protocluster    1..32944
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[4042:29519]"
                     /cutoff="20000"
                     /detection_rule="(novK or novJ or novI or novH or
                     SpcDK_cou)"
                     /neighbourhood="10000"
                     /product="aminocoumarin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      4043..29519
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(novK or novJ or novI or novH or
                     SpcDK_cou)"
                     /neighbourhood="10000"
                     /product="aminocoumarin"
                     /protocluster_number="1"
     cand_cluster    1..32944
                     /SMILES="NC(Cc1ccc(O)cc1)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(novK or novJ or novI or novH or
                     SpcDK_cou)"
                     /detection_rules="(t2pks2 or ksIII)"
                     /detection_rules="(LmbU or Neocarzinostat or fom1 or bcpB
                     or frbD or mitE or vlmB or prnB or CaiA or bacilysin or
                     orf2_PTase)"
                     /kind="interleaved"
                     /product="aminocoumarin"
                     /product="PKS-like"
                     /product="other"
                     /protoclusters="1"
                     /protoclusters="2"
                     /protoclusters="4"
                     /tool="antismash"
     subregion       1..32944
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000832"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..32944
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="aminocoumarin"
                     /product="PKS-like"
                     /product="other"
                     /region_number="1"
                     /rules="(novK or novJ or novI or novH or SpcDK_cou)"
                     /rules="(t2pks2 or ksIII)"
                     /rules="(LmbU or Neocarzinostat or fom1 or bcpB or frbD or
                     mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..32870
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[11802:12870]"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      11803..12870
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(t2pks2 or ksIII)"
                     /neighbourhood="20000"
                     /product="PKS-like"
                     /protocluster_number="2"
     protocluster    1..20326
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[0:654]"
                     /cutoff="20000"
                     /detection_rule="(LmbU or Neocarzinostat or fom1 or bcpB or
                     frbD or mitE or vlmB or prnB or CaiA or bacilysin or
                     orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="3"
                     /tool="antismash"
     proto_core      1..654
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(LmbU or Neocarzinostat or fom1 or bcpB or
                     frbD or mitE or vlmB or prnB or CaiA or bacilysin or
                     orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="3"
     cand_cluster    1..20326
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(LmbU or Neocarzinostat or fom1 or bcpB
                     or frbD or mitE or vlmB or prnB or CaiA or bacilysin or
                     orf2_PTase)"
                     /kind="single"
                     /product="other"
                     /protoclusters="3"
                     /tool="antismash"
     gene            1..654
                     /gene="cloE"
     gene            731..1819
                     /gene="cloF"
     CDS             731..1819
                     /codon_start=1
                     /gene="cloF"
                     /note="putative oxidoreductase; similar to novF of
                     novobiocin biosynthetic gene cluster"
                     /product="prephenate dehydrogenase"
                     /protein_id="AAN65221.1"
                     /transl_table=11
                     /translation="MHTAVIIGTGMIGTSIGLSLRKQGVDTYLMDVSPVALRISEAVGA
                     GMAEEPPEAVDLAVVAVPPAQVAPVIASHQSRGTARFYVDVAGVKVSSLRELEALGCDL
                     ATVVGGHPLVGRPGSGPLAAQDDLFDGRPWALVPAAETDASALNCALELVALCGAIPVV
                     LDAEAHDRAIALGTLVPQVVLTLAAARLTEADSIALRLLGGVWSEIPQLIGVDSATSWT
                     QALAANAAPVVSELEKLSLDLTTLLETLRAVADGSGSPAEPDGHLLEFIQRGIDGCNRI
                     PGRYGIPTETGLADIDVFVEDRPTELARLFRDVASAGVVMRGINISQRPDSLDRTVTIS
                     VTPRKAEDLLHELRRRKWPADA"
     gene            2399..3358
                     /gene="cloG"
     CDS             2399..3358
                     /codon_start=1
                     /gene="cloG"
                     /product="regulatory protein CloG"
                     /protein_id="AAN65222.1"
                     /transl_table=11
                     /translation="MSNSGDEEITSISPKITGKRERVSIGSLLPPSKLLRSGESTEHIR
                     ALAETEETLPPIVVHRETRRVIDGMHRLRAARFRGDELIEVVFVDGSSADVFVLAVELN
                     RAHGLPLTMAERKSAAARIMDSHPHWSDRKIARTTGLAASTIASLRSSSISGTVERRTG
                     QDGRIRPNDGTGGRQRASDLLAQNPNASVREVAKIARISVGTASDVRARLRRGEPAVTA
                     RQQAVLKLRPAAATQRTSPDYGRVLQSLRKDPSLRFTDVGRRLLRLLDGAAPGSVEQIA
                     QIADSVPEHCRIVVVDMARECAAAWQHLADQLAGRDTA"
     protocluster    2485..32944
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[22484:23459]"
                     /cutoff="20000"
                     /detection_rule="(LmbU or Neocarzinostat or fom1 or bcpB or
                     frbD or mitE or vlmB or prnB or CaiA or bacilysin or
                     orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="4"
                     /tool="antismash"
     proto_core      22485..23459
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(LmbU or Neocarzinostat or fom1 or bcpB or
                     frbD or mitE or vlmB or prnB or CaiA or bacilysin or
                     orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="4"
     gene            3573..3788
                     /gene="cloY"
     CDS             3573..3788
                     /codon_start=1
                     /gene="cloY"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1009:mbtH-like protein (Score: 110.6; E-value:
                     3.8e-34)"
                     /gene_kind="biosynthetic-additional"
                     /product="mbtH-like protein"
                     /protein_id="AAN65223.1"
                     /transl_table=11
                     /translation="MATNPFEDENGSYLVLINGEGQHSLWPSFADVPNGWTVIFNEASR
                     QDCLDYVNEHWTDMRPLSLQRAMGGE"
     gene            4043..5845
                     /gene="cloH"
     CDS             4043..5845
                     /NRPS_PKS="Domain: AMP-binding (26-424). E-value: 1.1e-99.
                     Score: 325.6. Matches aSDomain:
                     nrpspksdomains_cloH_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (531-596). E-value: 8.9e-19. Score:
                     59.3. Matches aSDomain: nrpspksdomains_cloH_PCP.1"
                     /codon_start=1
                     /gene="cloH"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminocoumarin: novH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     373.4; E-value: 2.5e-113)"
                     /gene_kind="biosynthetic"
                     /product="peptide synthetase-like protein"
                     /protein_id="AAN65224.1"
                     /sec_met_domain="novH (E-value: 0.0, bitscore: 1121.5,
                     seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLNTGLNKASHQSATTRTAPVTLAELWERTVRSRPSSPAIVSNSE
                     ILSYDEVNARANQLARLLLNEGAGPGRLVALALPRSSHMVISVLAVAKAGAAFLPVDVN
                     HPKERISYLLADAGPALLCTIRGAVPKLPADIGVPQLVLDSAKQTATLDALPDTDMTED
                     ERGGSLAATNLAYVIYTSGSTGRPKGVALTSAGLPALAAAKVATMQVTEDSRVLQFASP
                     SFDAYVTELLAAFTAGATLVLPGPDALAGDPLEKALRDGRVTHAVLPPAAAATVSPDAA
                     QDLRVLVVAGEACPAGLVEQWAPGRLLVNAYGPTECTVCATMTGPLTPTDEVTIGRPIP
                     GVSVHILDNALRPAAVGEIGELYISGAGLARGYLNRPDLTAQLFVANPFAADGERMYRT
                     GDLASMRADGDILFHGRIDDQVELRGFRIELGEVESVLSQHPDVAQAVAVLRAGAAEGP
                     QLLAYVVPTHDTTPTAGELREHASRFLPDYMVPSVYATIDAVPLTPGGKTDRAKLPEPI
                     KTTRSAGQGPRTPAEKILCDIFRDLFDLVEIDVRSNFFEMGGNSILAVDLIQRAQEAGL
                     VLLPRTVLDHPTIEQLAAIATLGE"
     aSDomain        4121..5314
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cloH_AMP-binding.1"
                     /evalue="1.10E-99"
                     /label="cloH_AMP-binding.1"
                     /locus_tag="cloH"
                     /protein_end="424"
                     /protein_start="26"
                     /score="325.6"
                     /specificity="consensus: tyr"
                     /tool="antismash"
                     /translation="WERTVRSRPSSPAIVSNSEILSYDEVNARANQLARLLLNEGAGPG
                     RLVALALPRSSHMVISVLAVAKAGAAFLPVDVNHPKERISYLLADAGPALLCTIRGAVP
                     KLPADIGVPQLVLDSAKQTATLDALPDTDMTEDERGGSLAATNLAYVIYTSGSTGRPKG
                     VALTSAGLPALAAAKVATMQVTEDSRVLQFASPSFDAYVTELLAAFTAGATLVLPGPDA
                     LAGDPLEKALRDGRVTHAVLPPAAAATVSPDAAQDLRVLVVAGEACPAGLVEQWAPGRL
                     LVNAYGPTECTVCATMTGPLTPTDEVTIGRPIPGVSVHILDNALRPAAVGEIGELYISG
                     AGLARGYLNRPDLTAQLFVANPFAADGERMYRTGDLASMRADGDILFHGRIDDQVELR"
     aSModule        4121..5830
                     /complete
                     /domains="nrpspksdomains_cloH_AMP-binding.1"
                     /domains="nrpspksdomains_cloH_PCP.1"
                     /locus_tags="cloH"
                     /monomer_pairings="tyr -> tyr"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       4307..4348
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloH_0001"
                     /evalue="1.50E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="cloH"
                     /protein_end="102"
                     /protein_start="88"
                     /score="15.1"
                     /tool="antismash"
                     /translation="LAVAKAGAAFLPVD"
     CDS_motif       4565..4621
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloH_0002"
                     /evalue="6.90E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="cloH"
                     /protein_end="193"
                     /protein_start="174"
                     /score="30.8"
                     /tool="antismash"
                     /translation="AYVIYTSGSTGRPKGVALT"
     CDS_motif       4736..4768
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloH_0003"
                     /evalue="2.20E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="cloH"
                     /protein_end="242"
                     /protein_start="231"
                     /score="-0.4"
                     /tool="antismash"
                     /translation="LAAFTAGATLV"
     CDS_motif       4976..5002
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloH_0004"
                     /evalue="1.10E-03"
                     /label="NRPS-A_a5"
                     /locus_tag="cloH"
                     /protein_end="320"
                     /protein_start="311"
                     /score="11.5"
                     /tool="antismash"
                     /translation="YGPTECTVC"
     CDS_motif       5108..5194
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloH_0005"
                     /evalue="1.40E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="cloH"
                     /protein_end="384"
                     /protein_start="355"
                     /score="52.5"
                     /tool="antismash"
                     /translation="VGEIGELYISGAGLARGYLNRPDLTAQLF"
     CDS_motif       5279..5344
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloH_0006"
                     /evalue="9.00E-11"
                     /label="NRPS-A_a8"
                     /locus_tag="cloH"
                     /protein_end="434"
                     /protein_start="412"
                     /score="33.8"
                     /tool="antismash"
                     /translation="FHGRIDDQVELRGFRIELGEVE"
     CDS_motif       5384..5407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloH_0007"
                     /evalue="9.60E-01"
                     /label="NRPS-A_a2"
                     /locus_tag="cloH"
                     /protein_end="455"
                     /protein_start="447"
                     /score="3.7"
                     /tool="antismash"
                     /translation="AVLRAGAA"
     aSDomain        5636..5830
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cloH_PCP.1"
                     /evalue="8.90E-19"
                     /label="cloH_PCP.1"
                     /locus_tag="cloH"
                     /protein_end="596"
                     /protein_start="531"
                     /score="59.3"
                     /tool="antismash"
                     /translation="EKILCDIFRDLFDLVEIDVRSNFFEMGGNSILAVDLIQRAQEAGL
                     VLLPRTVLDHPTIEQLAAIA"
     gene            5849..7072
                     /gene="cloI"
     CDS             5849..7072
                     /codon_start=1
                     /gene="cloI"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminocoumarin: novI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007:cytochrome P450 (Score: 314.6; E-value: 1.5e-95)"
                     /gene_kind="biosynthetic"
                     /product="cytochrome P450"
                     /protein_id="AAN65225.1"
                     /sec_met_domain="p450 (E-value: 1.3e-15, bitscore: 47.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="novI (E-value: 9e-260, bitscore: 851.9,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTRPTVSPDELEQIDLASPILHAEYELGEVFRYLRANRPMYWQQ
                     PRGEQPGFWVISRYADVNEVYKDKAHFTTEHGNALATLLTGGDSASGAMLAVTDGVRHH
                     QVRNLLSKGFSPQMLDLIANSLRETVDGLLLAALDRGECDAAQDIAANVPLGAICDLLE
                     IPQTDRKYLLGLTAHAWSTDYADETPEEGWVAKNEILLYFSKLLKERRGGDRDDMVSLL
                     ANCRIDGHPLNAAEQVANCYGLMIGGDETGRHAITGTILALIENPDQWRALKNGDVDLK
                     TATEEALRWTVPSLHGGRKATGDVVINGQQIKAGDVVSVWISSANRDEAIFDAADEFKL
                     ARTPNKHFTFAYGSHYCLGHYLGRMEVYAVLDGLRRLVGDLEQIGEERWIYSSILHGMS
                     SLPIRITV"
     gene            7226..8002
                     /gene="cloJ"
     CDS             7226..8002
                     /NRPS_PKS="Domain: PKS_KR (13-186). E-value: 4.8e-22.
                     Score: 70.6. Matches aSDomain:
                     nrpspksdomains_cloJ_PKS_KR.1"
                     /codon_start=1
                     /gene="cloJ"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminocoumarin: novJ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     243.6; E-value: 3.6e-74)"
                     /gene_kind="biosynthetic"
                     /product="b-ketotyrosyl-reductase"
                     /protein_id="AAN65226.1"
                     /sec_met_domain="adh_short (E-value: 1.1e-38, bitscore:
                     123.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="novJ (E-value: 7.7e-154, bitscore: 501.1,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPAGSPVAYEPVAMVTGAGRGIGAATAERLAAEGMAVIVVDRA
                     EQDTTATVSAIRAAGGRARGIGCDVAVAHAVTAAVASAVEEFGHVDVLVNCAGVNQDRL
                     LLTMSDQEWDTVLDVNLGGTMRCSFAVGRHMCRQGHGRIINFSSVAARGNAGQTNYATA
                     KGAIAGFTRTLAAELGPHGVTVNAIAPGFVATPMVDELIERLGVDRDTALLEAAMSSAV
                     GRIGTPEEIAAAVAFVTRQESGYLTGETIHVEGGRR"
     aSDomain        7265..7783
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cloJ_PKS_KR.1"
                     /evalue="4.80E-22"
                     /label="cloJ_PKS_KR.1"
                     /locus_tag="cloJ"
                     /protein_end="186"
                     /protein_start="13"
                     /score="70.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAMVTGAGRGIGAATAERLAAEGMAVIVVDRAEQDTTATVSAIRA
                     AGGRARGIGCDVAVAHAVTAAVASAVEEFGHVDVLVNCAGVNQDRLLLTMSDQEWDTVL
                     DVNLGGTMRCSFAVGRHMCRQGHGRIINFSSVAARGNAGQTNYATAKGAIAGFTRTLAA
                     ELGPHGVTVN"
     CDS_motif       7274..7348
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloJ_0001"
                     /evalue="1.60E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="cloJ"
                     /protein_end="41"
                     /protein_start="16"
                     /score="11.1"
                     /tool="antismash"
                     /translation="VTGAGRGIGAATAERLAAEGMAVIV"
     CDS_motif       7655..7714
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloJ_0002"
                     /evalue="1.20E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="cloJ"
                     /protein_end="163"
                     /protein_start="143"
                     /score="21.0"
                     /tool="antismash"
                     /translation="INFSSVAARGNAGQTNYATA"
     gene            7999..8736
                     /gene="cloK"
     CDS             7999..8736
                     /codon_start=1
                     /gene="cloK"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminocoumarin: novK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     91.4; E-value: 1.1e-27)"
                     /gene_kind="biosynthetic"
                     /note="putative oxidoreductase"
                     /product="b-ketotyrosyl-reductase"
                     /protein_id="AAN65227.1"
                     /sec_met_domain="novK (E-value: 8.4e-135, bitscore: 438.8,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGVAVVAGGSEHTGLAVALRLAAGGFDVALLDTEFTAADKTVRR
                     IEESGRRCITVEAELTDARSVGVAFGQVRTELSSPAVLVTCVGPEPVPDGLPEDEFADE
                     QRYTLVRRSLRPAFVCCQAGAGQLLHHRCGRIIIVTEPVDVSENAWRTSQPVLAGLIGF
                     TRSAALELARSGITVNLIAPADCAVDSRAPAHQPAVNDSAGSYADGVAHVTEFLVDEQA
                     AGITGQAIYVAASPAEVPLLRER"
     gene            8743..10326
                     /gene="cloL"
     CDS             8743..10326
                     /NRPS_PKS="Domain: AMP-binding (18-419). E-value: 2.4e-72.
                     Score: 235.6. Matches aSDomain:
                     nrpspksdomains_cloL_AMP-binding.1"
                     /codon_start=1
                     /gene="cloL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     281.3; E-value: 2e-85)"
                     /gene_kind="biosynthetic-additional"
                     /note="cloL; similar to novobiocic acid synthetase"
                     /product="amide synthetase"
                     /protein_id="AAN65228.1"
                     /sec_met_domain="AMP-binding (E-value: 5.8e-74, bitscore:
                     239.9, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANKDHGPEHYVTRILAEATRDGAQPVVRWRDTVITGTELHRSVQ
                     RVATALREAGVARDHAVAILTQVNSPWMLIVRYAAHLLGASVVYITGANHGTVTHDLPV
                     TTRVRMLREAGASVLVFDERNAQLAETVNETVPDKLVLCGLGHPASGTVTVDGRPVEDV
                     SVEFAPQAPELAMVLYTSGTTGQPKGVCRLFRSWNASVLGGAMHPRPAYLAMTAVSHTA
                     GLIVDMALAAGGSVLLREKFDPGDFLRDVAQHRITETVMGVAQLYAILNHPDVRTADLS
                     SLRHLLYLGCPASPERLQEAATVLPGVLAQSYGSTEAGRITVLREADHERPELLATVGQ
                     AMPGVTIAIRDPETGRDLPVNQIGEVVVHSPEAMGGYVADPEHTARVVRDGWVHTGDFG
                     SVDERGYVRLFGRMHEMVKVQDTRVSPTEVEKVLVGCPGVVDACVYGHRRSDLIEELHA
                     AVVLSTDGAPSFAALRDHVAQAMTPTHAPIRFVRWRQFPINNTGKVDRLRIREVSAEAR
                     GESPDVLVDR"
     aSDomain        8797..9999
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cloL_AMP-binding.1"
                     /evalue="2.40E-72"
                     /label="cloL_AMP-binding.1"
                     /locus_tag="cloL"
                     /protein_end="419"
                     /protein_start="18"
                     /score="235.6"
                     /specificity="consensus: X"
                     /tool="antismash"
                     /translation="ATRDGAQPVVRWRDTVITGTELHRSVQRVATALREAGVARDHAVA
                     ILTQVNSPWMLIVRYAAHLLGASVVYITGANHGTVTHDLPVTTRVRMLREAGASVLVFD
                     ERNAQLAETVNETVPDKLVLCGLGHPASGTVTVDGRPVEDVSVEFAPQAPELAMVLYTS
                     GTTGQPKGVCRLFRSWNASVLGGAMHPRPAYLAMTAVSHTAGLIVDMALAAGGSVLLRE
                     KFDPGDFLRDVAQHRITETVMGVAQLYAILNHPDVRTADLSSLRHLLYLGCPASPERLQ
                     EAATVLPGVLAQSYGSTEAGRITVLREADHERPELLATVGQAMPGVTIAIRDPETGRDL
                     PVNQIGEVVVHSPEAMGGYVADPEHTARVVRDGWVHTGDFGSVDERGYVRLFGRMHEMV
                     KV"
     CDS_motif       9265..9315
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloL_0001"
                     /evalue="2.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="cloL"
                     /protein_end="191"
                     /protein_start="174"
                     /score="23.3"
                     /tool="antismash"
                     /translation="AMVLYTSGTTGQPKGVC"
     CDS_motif       9817..9900
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloL_0002"
                     /evalue="2.60E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="cloL"
                     /protein_end="386"
                     /protein_start="358"
                     /score="13.4"
                     /tool="antismash"
                     /translation="PVNQIGEVVVHSPEAMGGYVADPEHTAR"
     gene            10340..11512
                     /gene="cloM"
     CDS             10340..11512
                     /codon_start=1
                     /gene="cloM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062:glycosyltransferase, MGT family (Score: 287.8;
                     E-value: 2.7e-87)"
                     /gene_kind="biosynthetic-additional"
                     /product="glycosyltransferase"
                     /protein_id="AAN65229.1"
                     /sec_met_domain="MGT (E-value: 1.8e-116, bitscore: 380.3,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLFTSLPGIGHLFPMVPLAWALQAAGHTVLVATDREFLPVVTA
                     AGLPGAAVLDPIDPVELFRPAGPSGGPVSPAESTGHRCAESGIRALPAIRALVDVWHPN
                     LVIAEPMELAGPAAAAIAGVPWVRHSYGLAPPQRLLSAAVAALDTELAVLGLSPLGRPA
                     RTIDVCPDSLQPSDAVATTPMRYVPYNGPACVPDWLLAGPSARPRVCLTLGTSLPRRDP
                     QVAPLWRLLLDELVALDHEVVIAIDERHRPLLGHLPGGVRAARIPLCDLLPTCTAIVHH
                     GGSGSTMAAASFGVPQLVIPHFADHFANAERITAVGAGMSLPHDTDDPARIAAACALIT
                     GDGPYRAVSSQLANENASRPKPTEVAQDLVALALEHDTVEHNRWGNYARW"
     gene            11506..11793
                     /gene="cloN1"
     CDS             11506..11793
                     /NRPS_PKS="Domain: PP-binding (32-80). E-value: 1.2e-06.
                     Score: 20.8. Matches aSDomain:
                     nrpspksdomains_cloN1_PP-binding.1"
                     /codon_start=1
                     /gene="cloN1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="non-experimental evidence, no additional
                     details recorded"
                     /product="acyl carrier protein"
                     /protein_id="AAN65230.1"
                     /sec_met_domain="PP-binding (E-value: 6.3e-07, bitscore:
                     20.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSGPTELEHVLTRLEILLNDVWDQRPAGAATSATAPLVSLGVDS
                     LTLALLLDKVGREFHIDWTADTPPGAASSLRSIADLVLRRDGGGATAAEA"
     aSDomain        11602..11745
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cloN1_PP-binding.1"
                     /evalue="1.20E-06"
                     /label="cloN1_PP-binding.1"
                     /locus_tag="cloN1"
                     /protein_end="80"
                     /protein_start="32"
                     /score="20.8"
                     /tool="antismash"
                     /translation="SATAPLVSLGVDSLTLALLLDKVGREFHIDWTADTPPGAASSLRS
                     IAD"
     gene            11803..12870
                     /gene="cloN2"
     CDS             11803..12870
                     /codon_start=1
                     /gene="cloN2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PKS-like: ksIII"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 106.6; E-value: 2.2e-32)"
                     /gene_kind="biosynthetic"
                     /product="acyltransferase"
                     /protein_id="AAN65231.1"
                     /sec_met_domain="ksIII (E-value: 8.7e-76, bitscore: 245.7,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTSGIYVAGIGVFRPKTESVDVAVRQGLVSKYAADASGITGVAV
                     AGDVSPPEIALIAAQQALKSSGLSADDIGLLLCTGVWHQGPDGWGPQYFLQRHLLGDDL
                     LAVELRHGCNGTFSALELAVPYLRSAPHVGGALITASDNFGTPLIDRWNPGEGLAFLGD
                     GAGAVVLGTSPGFAELLSICTASFSGMEEVHRAGEPLFPPGATTGTFLDYGARAARFQQ
                     KATDDGTWVQFLLGHQKHNLECVEQALHEAGVDARDIKTVVIHSMPRQAAASYLKILGF
                     SLESSTWEFSRTTGHLGAGDHLAALHHLLSTGKVGPGDNLLLCGSSPGVTYKAAVIRIL
                     DTAALRNQEARPDGL"
     gene            12860..13990
                     /gene="cloN3"
     CDS             12860..13990
                     /codon_start=1
                     /gene="cloN3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006:acyl-CoA dehydrogenase (Score: 336; E-value:
                     4.9e-102)"
                     /gene_kind="biosynthetic-additional"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="AAN65232.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.7e-13, bitscore:
                     41.1, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 6.6e-26, bitscore:
                     81.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.7e-35, bitscore:
                     113.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFDLSPQQQQRVDHIRAGAGKLPSAKPDGVAGKDSWLAAAELGM
                     TGLCLPTEHGGGGLGALDTALCLEAFCAGGADTGLAFGIAAHLLACGTVLTDHAGDPVR
                     AELLRGLTSGTVIAANAMTEDDAGSDLSRLATTAVADSDSYVLNGKKSFVSNAPLADVF
                     ITYAATTPSAGYLGMSAFAVPRTLPGLRINSPLAKMGLNGCAAAQVEFTDCKVPGRYLL
                     GPENQGNSIFQRSMIWERACLPAIYLGAMEVQLAQCVDHAQSRRQFGRSIGTFQAISHR
                     LATMKLRLETSRLLLYRACWYLDQGRSAVEAVALAKTAVAEAAVANALDAVQVFGARGY
                     LAADGIGQQLQNAIPLNIFSGTTEIQREVVARSMGL"
     gene            14109..15614
                     /gene="cloN4"
     CDS             14109..15614
                     /NRPS_PKS="Domain: AMP-binding (12-401). E-value: 4.7e-94.
                     Score: 307.1. Matches aSDomain:
                     nrpspksdomains_cloN4_AMP-binding.1"
                     /codon_start=1
                     /gene="cloN4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     333.8; E-value: 2.4e-101)"
                     /gene_kind="biosynthetic-additional"
                     /product="acyl-CoA synthetase"
                     /protein_id="AAN65233.1"
                     /sec_met_domain="AMP-binding (E-value: 2.8e-100, bitscore:
                     326.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDRRGLHDLLAASAARTPNAPAVIGPAGSMSYGELDERANDLAG
                     RLSGRGIEKGDRVLIWSPKSANAIAAMQAVLRLGAIYIPVDPLTPPERFAAIARESGAL
                     ALCAPDDLSARVPSPLRDRLACVDLDAAPVPNALPTAPVNTRVEPDDLAYILYTSGSTG
                     TPKGVCVSHRSALAFIDWAVAELAPGPQDRFANHSGLSFDLSVLDLYAAFTVGAAVCPI
                     HAEFAYAPERLVEFLHRERISVWYSVPSVLILMLRDGGLLDRPAPETLRALLFAGEPFP
                     IGYVRALAAWSDARLLNLYGPTETNVCTYHEVRPADLARDLPVPIGRPCSGDRVWARRP
                     DGSEAEPGEEGELVVSGPTVFAGYWGRQPQEGPYATGDRVKVRPDGSFDYLGRHDDMVK
                     IRGHRIELGDVVAALNSHPGVAEAAVVAVGEGLDRNLAAFVIRSQGSSFGNVALRRHLA
                     DRLAPHMIPGDIRFVDQLPHNDRGKLDLAALQIPLHGAQKVQG"
     aSDomain        14145..15311
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cloN4_AMP-binding.1"
                     /evalue="4.70E-94"
                     /label="cloN4_AMP-binding.1"
                     /locus_tag="cloN4"
                     /protein_end="401"
                     /protein_start="12"
                     /score="307.1"
                     /specificity="consensus: ala"
                     /tool="antismash"
                     /translation="ASAARTPNAPAVIGPAGSMSYGELDERANDLAGRLSGRGIEKGDR
                     VLIWSPKSANAIAAMQAVLRLGAIYIPVDPLTPPERFAAIARESGALALCAPDDLSARV
                     PSPLRDRLACVDLDAAPVPNALPTAPVNTRVEPDDLAYILYTSGSTGTPKGVCVSHRSA
                     LAFIDWAVAELAPGPQDRFANHSGLSFDLSVLDLYAAFTVGAAVCPIHAEFAYAPERLV
                     EFLHRERISVWYSVPSVLILMLRDGGLLDRPAPETLRALLFAGEPFPIGYVRALAAWSD
                     ARLLNLYGPTETNVCTYHEVRPADLARDLPVPIGRPCSGDRVWARRPDGSEAEPGEEGE
                     LVVSGPTVFAGYWGRQPQEGPYATGDRVKVRPDGSFDYLGRHDDMVKIR"
     CDS_motif       14328..14366
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloN4_0001"
                     /evalue="1.20E-02"
                     /label="NRPS-A_a2"
                     /locus_tag="cloN4"
                     /protein_end="86"
                     /protein_start="73"
                     /score="9.4"
                     /tool="antismash"
                     /translation="AVLRLGAIYIPVD"
     CDS_motif       14478..14513
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloN4_0002"
                     /evalue="3.20E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="cloN4"
                     /protein_end="135"
                     /protein_start="123"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="LACVDLDAAPVP"
     CDS_motif       14565..14624
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloN4_0003"
                     /evalue="8.60E-11"
                     /label="NRPS-A_a3"
                     /locus_tag="cloN4"
                     /protein_end="172"
                     /protein_start="152"
                     /score="33.6"
                     /tool="antismash"
                     /translation="AYILYTSGSTGTPKGVCVSH"
     CDS_motif       14739..14774
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloN4_0004"
                     /evalue="3.70E+00"
                     /label="NRPS-A_a2"
                     /locus_tag="cloN4"
                     /protein_end="222"
                     /protein_start="210"
                     /score="1.9"
                     /tool="antismash"
                     /translation="AAFTVGAAVCPI"
     CDS_motif       15147..15212
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloN4_0005"
                     /evalue="5.70E-07"
                     /label="NRPS-A_a6"
                     /locus_tag="cloN4"
                     /protein_end="368"
                     /protein_start="346"
                     /score="21.9"
                     /tool="antismash"
                     /translation="PGEEGELVVSGPTVFAGYWGRQ"
     CDS_motif       15276..15338
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_cloN4_0006"
                     /evalue="1.50E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="cloN4"
                     /protein_end="410"
                     /protein_start="389"
                     /score="33.1"
                     /tool="antismash"
                     /translation="YLGRHDDMVKIRGHRIELGDV"
     gene            15618..15887
                     /gene="cloN5"
     CDS             15618..15887
                     /NRPS_PKS="Domain: PP-binding (20-82). E-value: 3.1e-12.
                     Score: 38.7. Matches aSDomain:
                     nrpspksdomains_cloN5_PP-binding.1"
                     /codon_start=1
                     /gene="cloN5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /note="similar to acyl carrier protein"
                     /product="acyl carrier protein"
                     /protein_id="AAN65234.1"
                     /sec_met_domain="PP-binding (E-value: 1.6e-12, bitscore:
                     38.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQTREDISSELLTFIRESFLAGDPEGELDADTPLLELGILNSL
                     NTATLIAHLGERFGVHVPLMDVTATTFKSVRTLSEIVHESLSRK"
     aSDomain        15678..15863
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cloN5_PP-binding.1"
                     /evalue="3.10E-12"
                     /label="cloN5_PP-binding.1"
                     /locus_tag="cloN5"
                     /protein_end="82"
                     /protein_start="20"
                     /score="38.7"
                     /tool="antismash"
                     /translation="FLAGDPEGELDADTPLLELGILNSLNTATLIAHLGERFGVHVPLM
                     DVTATTFKSVRTLSEIV"
     gene            15945..17630
                     /gene="cloN6"
     CDS             15945..17630
                     /codon_start=1
                     /gene="cloN6"
                     /gene_functions="other (smcogs) SMCOG1277:Radical SAM
                     domain protein (Score: 97; E-value: 1.8e-29)"
                     /gene_kind="other"
                     /note="unknown protein, similar to couN6 of coumermycin A1"
                     /product="methyltransferase"
                     /protein_id="AAN65235.1"
                     /transl_table=11
                     /translation="MFLLHAPSVYDFRDRDDILFAYLSDSDSVNVTSVYEMYPIGWFSI
                     KQQLADHDFDCQIVNIASLMLKHPDLDVERLIERLEAPVFGFDLHWMTQCNGAIELAEV
                     VKRIHPESLIVFGGISATYFARELIQYPQVDVVVQGYDTLAPITQLVEAVVRGGRDFSS
                     IPNLLYKGNDRVETTGFSHKPATDYNNVRNDWSYYQNTPVTPLASKLIMTLPNTGCAHD
                     CGWCGGSRFAYRNIMEVGTKTLVQKDNDLIVEELKTMGEAAKHTSIYALQCYSEGKARM
                     HTYLDAVHDLGYRSVFFEQFNLTPHDTLKKMGTSTDSYIMLSPESHDPKISRAAGRGTY
                     TMAEMEEWIPRALDAGVKGVMIWFFIGMPYQDRQSVRDTVTYSEHLIRKFAGQPVLPLI
                     CPMVPFLDPGCRFFEEPDKHGYRIHHRTLEEHRQAMVEPLWYRRLNYETKWLSRRGIQD
                     VSYEAIERLVSIKGEHGVLSSVFCEAVLKTIDQTKRLLAEMDHALSLDGRLPATLRDEM
                     RAYNRKILAYSSDQILPIPRPFGGRWFDDVTVPEEMIRELSMTP"
     gene            17679..18515
                     /gene="cloN7"
     CDS             17679..18515
                     /codon_start=1
                     /gene="cloN7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036:alpha/beta hydrolase fold protein (Score: 71.2;
                     E-value: 1.9e-21)"
                     /gene_kind="biosynthetic-additional"
                     /product="acyl transferase"
                     /protein_id="AAN65236.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.5e-15, bitscore:
                     47.2, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 3.8e-17, bitscore: 53.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANDKPVVQSLKVPGARLHYEIQGAGPLLVVVGLPMGCKGFAPIS
                     QLLAEHFTVVTFDPRGVIGSPLEDPTQEAEPELMADDVHRLISTLDAGPVYLFGSSGGA
                     VTALVLAAQHPEQVRALVAHEPPLLELLIDREQMRAAIDEICDLYRENRPVALQKYLAL
                     ANIRLHRPAQQPPEPNSFTDPEDVWTILDRLFHHTLRPTTRYRPDINALRPMGDRIVIA
                     GGSTAEGSLFHRTAVALADQLGTKLVEFPGDHTGFLTESESFAQLLFEVLTNARPA"
     gene            18752..20326
                     /gene="clohal"
     CDS             18752..20326
                     /codon_start=1
                     /gene="clohal"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Trp_halogenase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1119:halogenase (Score: 372; E-value: 7.6e-113)"
                     /gene_kind="biosynthetic-additional"
                     /product="halogenase"
                     /protein_id="AAN65237.1"
                     /sec_met_domain="Trp_halogenase (E-value: 2.5e-30,
                     bitscore: 96.5, seeds: 23, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSENQEYDVIVIGGGPGGSMVSSLLADGGKKVLVLEVAKFPRYHI
                     GESLLLGTVDLLDKIGVREKLEAGDYIKKYGVEWVWGEQREPWKVDFRNAVSVTHDYTY
                     QVERGPFDKMLLDNAREHGVDVREQHRVTNFSIDDNGRSTVNYRRTDTGETGTATARWL
                     VDASGQGGLVTKRLHTQEWDPYLKNMAVWSYWKGVKRSEGEDAGNIFLPTFDDGWWWCI
                     PLRDDITSIGAVVDRESLNALKSTRVRQYYLDSIEKTPELASRTENAELVDDMHVQRDW
                     SYIYDRFCGDGYIAIGDAACFIDPLFSTGVHLAMLSGFLAATVVNTILDKPELDTARML
                     QFYEGAYRKEFARLRDQVYFLYAGNKGSKESYFWHARSHFGVPSIEPEKAFVSLIAGAF
                     AHRAWYNHYAKHLDVSADLKKSVESMFNGAGIDLDTPLIASACGSVVNDFAVDGRYLRE
                     ARSLVHTNGASIAYTPAVRAAVEHADGKRTGREIIEIITDRGIDSEDRARSIVHEVISY
                     GFVEPKA"
     gene            20651..21484
                     /gene="cloP"
     CDS             20651..21484
                     /codon_start=1
                     /gene="cloP"
                     /product="O-methyltransferase"
                     /protein_id="AAN65238.1"
                     /transl_table=11
                     /translation="MEVTPIVVSVADNSLQAQPEGPTQGTSSGSWLYLNLMKKVLAGTV
                     YEDPAHRQNFSHDDATYREEVRNEGRDWPANAHTMIGIKRLENIQQCVEDVIGNNIPGD
                     LAETGVWRGGACIFMRGILRAHDVRDRTVWVADSFQGIPDVGADGYPGDRRMALHRHNA
                     VLAVSEDEVRRNFRNYDLLDEQVRFLPGWFKDTLPTAPIDALAVLRMDGDLYESTWDTL
                     TNLYPKVSVGGYVIVDDYLMCPPCKDAVDEYRARFDIADELIRIDRDGVYWQRTR"
     gene            22485..23459
                     /gene="cloQ"
     CDS             22485..23459
                     /codon_start=1
                     /gene="cloQ"
                     /gene_functions="biosynthetic (rule-based-clusters) other:
                     orf2_PTase"
                     /gene_kind="biosynthetic"
                     /note="unknown, similar to novQ of novobiocin biosynthetic
                     gene cluster"
                     /product="ABBA prenyltransferase"
                     /protein_id="AAN65239.1"
                     /sec_met_domain="orf2_PTase (E-value: 3.3e-80, bitscore:
                     260.2, seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPALPIDQEFDCERFRADIRATAAAIGAPIAHRLTDTVLEAFRDN
                     FAQGATLWKTTSQPGDQLSYRFFSRLKMDTVSRAIDAGLLDAAHPTLAVVDAWSSLYGG
                     APVQSGDFDAGRGMAKTWLYFGGLRPAEDILTVPALPASVQARLKDFLALGLAHVRFAA
                     VDWRHHSANVYFRGKGPLDTVQFARIHALSGSTPPAAHVVEEVLAYMPEDYCVAITLDL
                     HSGDIERVCFYALKVPKNALPRIPTRIARFLEVAPSHDVEECNVIGWSFGRSGDYVKAE
                     RSYTGNMAEILAGWNCFFHGEEGRDHDLRALHQHTESTMGGAR"
     gene            23456..24289
                     /gene="cloR"
     CDS             23456..24289
                     /codon_start=1
                     /gene="cloR"
                     /product="alpha-ketoacid-dependent oxygenase"
                     /protein_id="AAN65240.1"
                     /transl_table=11
                     /translation="MSKALANMPGDDYFRHPPVFDTYAEHRAYLKFRHAVALRHFARLG
                     FDQDGLAGLITVADPEHADTYWANPLAHPFSTITPADLIRVDGDSTETVDGQRRVNIAA
                     FNIHAEIHRARPDVQAVIHLHTVYGRAFSAFARKLPPLTQDACPFFEDHEVFDDYTGLV
                     LAKDDGRRIAKQLRGHKAILLKNHGLVTVGETLDAAAWWFTLLDTCCHVQLLADAAGGA
                     EPIPAEVARLTGQQLGSHLLGWNSYQPLHEATLARNPDLAAMAPALPPQTPALAR"
     gene            25119..25985
                     /gene="cloS"
     CDS             25119..25985
                     /NRPS_PKS="Domain: NAD_binding_4 (54-160). E-value: 4e-10.
                     Score: 31.0. Matches aSDomain:
                     nrpspksdomains_cloS_NAD_binding_4.1"
                     /codon_start=1
                     /gene="cloS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 92.9;
                     E-value: 4e-28)"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-4-keto-6-deoxyhexose reductase"
                     /protein_id="AAN65241.1"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.8e-09,
                     bitscore: 28.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.7e-103,
                     bitscore: 335.4, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNRWLVTGAAGMLGRDLVGVLQGLNESVVAVTRQDLDITDRFSV
                     RAVVSRYQPTTIVNCAAWTRFPEAEVSESEALLINGRGVRELASICSDRSIRLVHLSTD
                     YVFDGTSCQPYAESAATSPINAYGRTKLAGEQAVLELLPDDGTIVRTAWLYGRHGTNFI
                     RKMVRLEQMRKTVDVVDDQWGQPTWTVDLAQQIVALVRQGASGVFHGTSSGETTWYDIA
                     RMVFRLLGADPGRIRPVRSDQVAGGELRPRYTVLGHAAWREVGLTPIRHWATALTQSFP
                     LLVDGES"
     aSDomain        25281..25598
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cloS_NAD_binding_4.1"
                     /evalue="4.00E-10"
                     /label="cloS_NAD_binding_4.1"
                     /locus_tag="cloS"
                     /protein_end="160"
                     /protein_start="54"
                     /score="31.0"
                     /tool="antismash"
                     /translation="TTIVNCAAWTRFPEAEVSESEALLINGRGVRELASICSDRSIRLV
                     HLSTDYVFDGTSCQPYAESAATSPINAYGRTKLAGEQAVLELLPDDGTIVRTAWLYGRH
                     GT"
     gene            26019..27029
                     /gene="cloT"
     CDS             26019..27029
                     /NRPS_PKS="Domain: NAD_binding_4 (4-180). E-value: 2.5e-16.
                     Score: 51.3. Matches aSDomain:
                     nrpspksdomains_cloT_NAD_binding_4.1"
                     /codon_start=1
                     /gene="cloT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     322.8; E-value: 4e-98)"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="AAN65242.1"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.3e-16, bitscore:
                     51.3, seeds: 102, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 4.6e-20,
                     bitscore: 62.7, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="RmlD_sub_bind (E-value: 5.6e-24, bitscore:
                     75.5, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLLVTGGAGFIGSEFVRATLRGVLPGSSGTHITVLDKLTYSGNE
                     LNLAPIADLPNYRFVQGDICDRGLVDDVVAGHDAIVHFAAETHVDRSIDSAASFVRTNA
                     LGTQVLLEAASRHRLGRFVHISTDEVYGSIPEGAWTEVSPVAPNAPYAAAKAAGDLLAL
                     AWHRTRRLDVVVTRCTNNYGPYQYPEKLIPLFTTNILDGQQVPVYGDGRNRRQWLHVSD
                     HCRAIQLVLLGGRPGEVYHIGGGIELTNLELAEHILAACGVGWDMVRHVPDRLGHDLRY
                     SLETAKIRTELGFSPRVAFAEGLAETVEWYRTHRGWWEPLKNPDKATGSPSDAGR"
     aSDomain        26031..26558
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_cloT_NAD_binding_4.1"
                     /evalue="2.50E-16"
                     /label="cloT_NAD_binding_4.1"
                     /locus_tag="cloT"
                     /protein_end="180"
                     /protein_start="4"
                     /score="51.3"
                     /tool="antismash"
                     /translation="VTGGAGFIGSEFVRATLRGVLPGSSGTHITVLDKLTYSGNELNLA
                     PIADLPNYRFVQGDICDRGLVDDVVAGHDAIVHFAAETHVDRSIDSAASFVRTNALGTQ
                     VLLEAASRHRLGRFVHISTDEVYGSIPEGAWTEVSPVAPNAPYAAAKAAGDLLALAWHR
                     TRRLDVVVTRCTN"
     gene            27255..28517
                     /gene="cloU"
     CDS             27255..28517
                     /codon_start=1
                     /gene="cloU"
                     /product="C-methyltransferase"
                     /protein_id="AAN65243.1"
                     /transl_table=11
                     /translation="MQDIVRPINKCRVCGHNDWLDVVSFGSTPLAGNLLGKEDAPGGET
                     LFPLDVVVCRKCWLMTLRHVIEPDVLFGHYRYVASDAGSIIQHMRQLVELCIGWIGLTD
                     GDLVVEFGSNTGAHLQLFQQAGMRVLGVDPARNLADIANGRGVETIPAGFITEVGQEIA
                     SGHGPARLVYGRQCFAHIHDIHEVLNGVSALLAPDGLFFVEVPYLVELLANNQFDTIFH
                     EHLSYFSLGSLCRLFESHGLRVVDVHTADVHGGSIVVFAAPTTAGYEVRPAVAEMLAEE
                     RSQGIAEEGTYRKFAERTERVRAQIRELVCGVVAEGKSVAGYGAPTKGSALLAACGLGH
                     QEIRFCSDTTALKQGKILPGSRIPIWSPEQAGDHVPDYYLLLAWNYAPEIISKEKSFLE
                     NGGRFIVPIPEPRVISAESAL"
     gene            28629..29519
                     /gene="cloV"
     CDS             28629..29519
                     /codon_start=1
                     /gene="cloV"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminocoumarin: SpcDK_cou"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 251.6; E-value:
                     1.6e-76)"
                     /gene_kind="biosynthetic"
                     /note="cloV; glucose-1-phosphate thymidylyltransferase"
                     /product="dTDP-glucose synthase"
                     /protein_id="AAN65244.1"
                     /sec_met_domain="SpcDK_cou (E-value: 3.2e-205, bitscore:
                     670.5, seeds: 3, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGILLAGGTGSRLWPVTRAVSKQLIPVFDKPMIYYPLTTLMMAG
                     IREILVITRPEDQRQFRHLLGDGSQLGLRLEYAVQEQPEGIAQAFVLGAEFIGDQSVAL
                     VLGDNIFHGGGLGTRLREYSDPVGGRIFAYVVADPTAYAVVEFDEAGMAVSIEEKPADP
                     KSRYAVPGLYFYDNRVVEVARGLVPSERGELEITAVNETYLRWGQLRVTALDRGTAWLD
                     TGTFTSLVQASEYVRVVEERQGLKIGCVEEVAWRCGLIENDQLRELSRPLLKSGYGQYL
                     LDLLAERELKELKVS"
     gene            29516..30112
                     /gene="cloW"
     CDS             29516..30112
                     /codon_start=1
                     /gene="cloW"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /product="dTDP-4-keto-6-deoxyglucose 3,5-epimerase"
                     /protein_id="AAN65245.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 3.2e-63,
                     bitscore: 203.3, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLRPLGIEGVWEITPRQHADARGVFLDWYCVDRFAAEVGRPLRL
                     AQANLSVSARGVLRGIHFADVPPGQAKYVTCVRGAVFDVVVDLRVGSSTYGRWEGTRLD
                     DVSRRAVYLSEGIGHGFCAISDEATLCYLCSQTYNPASEHGVHPLDPELAINWPAGTPL
                     LSARDQDALLLSEARDSGLLPSYAACQALTALTRR"
     gene            30112..30873
                     /gene="cloZ"
     CDS             30112..30873
                     /codon_start=1
                     /gene="cloZ"
                     /note="CloZ"
                     /product="Unknown"
                     /protein_id="AAN65246.1"
                     /transl_table=11
                     /translation="MVRGVPTRGSARRGSGSWKSRLVAGTEASDRAPPAVAMAEPVAAG
                     WLRAVAAELARRQRDVMRVRRRTMPAENFLSYRKLSDHWLQFPNGDLLTPRLRYPVQRR
                     AAVVRLIQMVSAMGVHEAARFLGVPDTRPERRAGHQRLPIALFLNDRKIELLANRISDT
                     TCTTDQRHRRISLATRTLPPTHRATVWGQVAPRPDTTPPLDSPRKHQPPLTEYADQFVS
                     TIDQRNRTRVMPPSAAPSTGAGFGGRPGLAA"
     gene            31227..>32944
                     /gene="gyrBR"
     CDS             31227..>32944
                     /codon_start=1
                     /gene="gyrBR"
                     /note="GyrBR"
                     /product="clorobiocin-resistant gyrase B"
                     /protein_id="AAN65247.1"
                     /transl_table=11
                     /translation="MTTYDTRTATDTPGSQQPGHVGAASYDANAITVLDGLDAVRKRPG
                     MYIGSTGERGLHHLVQELVDNSVDEALAGVADRIDVTILADGGVRVVDNGRGIPVGTHP
                     VEKRPAVEVVLTVLHAGGKFGGGGYAVSGGLHGVGLSVVNALSTRLSAEIWTDGYRWTQ
                     DYRDGAPTAPLARHEATSRTGTSLTFWADGDIFETTEYSFETLARRFQEMAFLNRGLTL
                     TLTDERPSARATAAADEADSDPAAKTVSYRYDGGITDFVAYLNSRKGEPAHPSVITIAA
                     EDTERLLSAEVALQWNGQYTDSVYSYANGIHTHEGGTHEEGFRTALTTVVNRYAREKKL
                     LREKDANLSGEDVREGLTAIISVKLGEPQFEGQTKTKLGNTEARTFVQKIVHEHLTDWF
                     DRNPNEAADIVRKAIQAATARVAARKARDLTRRKGLLETAALPGKLSDCQSNDPAMSEI
                     FVVEGDSAGGSAKSGRNPQYQAILPIRGKILNVEKARIDKILHNQEIQALISAFGTGVH
                     EDFDIAKLRYHKIILMADADVDGQHINTLLLTFLFRFMRPLVEEGHVYLSRPPLY"
ORIGIN
        1 gtggtcgcgt ctggtcagac agcttcgaag gctgggggaa gcggcaccac tccggtgagg
       61 ccgactgcgg gagaggcgac ccccgttgac agcaagcaat caaggcacgc ctcgtatctc
      121 ggcctggagg tttcggccga gaggaccagg cttcagatcc cgcgagatct ctccctggag
      181 gcatggtgcc gcctcggcgg aaggatcctc gcggtatgcg actcgtcggc ctggtggatc
      241 ggtgattggt tggtgttcgg acagaaccag tacggtgacc gataccgccg ggcaatgaag
      301 gagaccaagc tcgactatca aacgctgcga aattatgcct gggtggcgag gaaattcgag
      361 ccgtcccgcc ggcgagacgg cctcacattc caacatcaca tggaagtggc agctctctcg
      421 gaagccgaac aggaccactg gctcgacttc gcagtgcgac tgaactggtc gaggaacgag
      481 ctgcgcaaac agatccgggc cagcatgtcg ggcgaagaag gtgatctccg gcgccaggtt
      541 cagctcagcc tccagttaga cgagttacgt ctcgaacgat ggagggaggc ggcgcggcgt
      601 agcaacctga ctctgacgga ttggatctca tccgtcgtcg acgaagccat ttgatcgaat
      661 gcgctcatac ggcatcgctg ccttacggca ctgctgcgtg acggccccga aaggattacg
      721 ggagatcaac gtgcacacgg ccgtgataat cgggaccgga atgatcggca cgtcgatcgg
      781 tctgtcgctg cggaagcaag gcgtcgacac ctacctcatg gacgtcagtc ccgtcgcact
      841 gcgcatttcc gaagcggtcg gtgccgggat ggccgaggaa ccgccggaag cggtggacct
      901 ggcggtggtc gccgtgccgc cggcccaagt ggcaccggtg atcgcgtctc accagtcgag
      961 gggaaccgct cgcttttacg tcgacgtggc gggagtgaag gtctcgtcct tgcgtgaact
     1021 cgaagcactg ggttgtgacc ttgccactgt ggtgggtggt catccactgg tgggacggcc
     1081 gggatccggt cctttggcgg cgcaggacga cctgttcgac ggacggccgt gggcgctcgt
     1141 gcccgcagcg gaaacagatg cttccgcact gaactgcgct ctcgaactgg tcgccttgtg
     1201 cggggcgata ccggtcgtcc tggatgccga ggcgcacgac cgggcgatcg ccctcggcac
     1261 gctcgtcccc caggtcgttc tcacgctcgc cgccgctcgc ttgacggagg cggacagcat
     1321 cgcgttacgg ctgctgggag gcgtgtggtc ggagataccc cagctcatcg gggtcgactc
     1381 cgccacatcg tggacacagg ccctcgccgc gaatgcggct ccggtcgtga gtgagctgga
     1441 aaagctgagt ctggacctga caactctgtt ggagacactc agagctgtcg cggacggaag
     1501 cggctcgccc gcggagcctg atggtcatct gctggagttc atccagcgtg gcatcgatgg
     1561 ctgcaaccgc attcccggca ggtacgggat ccccacggag accggactcg cggacatcga
     1621 tgttttcgtc gaagaccggc cgacagagtt ggctcgcctc ttcagggacg tggcaagcgc
     1681 cggggtggtg atgcgcggca tcaacatctc gcagcggccg gacagcctcg accgtacggt
     1741 caccatttcg gtcactccgc gcaaggctga ggacctcctg cacgaactac gtcgcaggaa
     1801 gtggccagcg gacgcctgac atcgggggag gggggtcaca ggtcgaggga ggctgccagg
     1861 gcctcctcag cgatgtgccc gaggctgtcg gagggcgcgg cgtagacgcc ctccgcgcga
     1921 gccctcccgg ggtccgttca ccgcgcggca cggtccgtcg gtgaacactc gcgcatcagc
     1981 ggcgcttacg gatccggcac cgatgcccag gacgaaccgt cgccggctgc gccggcgagg
     2041 gcgatcgaag cggcccacct cgaccagcag cgaggggtgg gccagggccg acacctcggg
     2101 tgagcgtgct cgccgggcgc acctgcgcga agaactcgac atgcacggcg ccgatggcct
     2161 acagggcgct gatgccggtg acttagaatc gaccgggagg aatcggcgat gggctcaccg
     2221 ccaaccactc acaggccgcg ccgaatagaa ccgacgattc cgcacttctg cgccgcccgg
     2281 cggcgaatga gcgatgaacg tgcgtggatg ctgctgagcc tggccaagac ctgcctctgg
     2341 tcacccatgt cctgcacacg ctgatccgga ccgaatcatt atgtcctacg ggggtcatat
     2401 gagtaacagc ggtgatgagg agatcacgtc aatttcgcct aaaataaccg gaaaaaggga
     2461 acgagtctcg atcggttctt tattgccgcc atctaaacta ctgcggtctg gcgagagtac
     2521 cgaacacatt cgtgcactgg ctgagacaga ggagaccctg ccaccgattg tcgtgcaccg
     2581 tgagacacgg cgggtcatcg acggaatgca caggctgcgg gcagctcgtt tccgtggcga
     2641 cgaattaatc gaggtcgttt tcgtcgacgg ttcctcagcc gatgtgtttg tcctcgcggt
     2701 cgagctgaat cgtgcgcacg gcctgccgtt gacgatggcc gagcgtaaat ccgccgccgc
     2761 gcggatcatg gattcgcacc cgcactggtc cgaccgcaag atcgcacgga ccactggatt
     2821 ggcagccagc actatcgcgt ctttaaggtc gtcatccatc tctggcacgg tcgagcgtag
     2881 aaccgggcag gacggccgaa tccgacccaa cgatggcacg ggcggacggc agcgcgccag
     2941 cgacctgctg gcccagaatc cgaacgcgtc ggttcgcgaa gttgccaaaa tagcgcggat
     3001 ttcggtgggc accgccagcg atgtgcgcgc cagattgcgg cgaggcgagc cggcggtaac
     3061 cgcccgacag caggcggtcc tgaaactgcg cccggccgcg gcgacgcaac ggaccagtcc
     3121 ggactatggc cgcgtgctgc agagcctgcg caaggaccca tcgctgcgtt tcaccgacgt
     3181 cggccgacgc ttgctccggc tgcttgacgg cgccgccccg ggcagtgtcg agcagattgc
     3241 ccagatcgcg gacagcgtgc cggaacactg tcgaatcgtg gtggtagaca tggcccgcga
     3301 gtgcgcggcc gcatggcaac atctagccga ccagctcgcg ggccgagaca ccgcctgacg
     3361 gagaaatacg gtctgatccg gtggctgcgg gatgttcaac tgctcgaacc atacggttga
     3421 acatggtcac cgggtccgga tcggcatctt gaaccgcccc ggtgtgatga agaggatgga
     3481 gagacggctc agccctcgaa ccaccctcgc aacactccgg gcggtcaatg gtggaacaag
     3541 acgcgtgaaa taacatctgg gaggtattcg tcatggcgac gaacccgttc gaggacgaga
     3601 acggctccta tctggtcctg atcaatggcg aggggcagca ttctctgtgg ccttcgttcg
     3661 ctgatgttcc caacgggtgg actgtcattt tcaacgaggc gtcgcggcaa gactgcctcg
     3721 attacgtcaa tgagcattgg acagacatgc ggccgttgag cctgcagcgg gcgatgggtg
     3781 gcgagtagca tctgctcatt caaaagtgga tttggcaata tgagataaat tatcgaaggt
     3841 tgttcgaagg ccgccccgct ttacggcagg agcaaggcgt gattcaatcg cgcaaagcgt
     3901 tcgatgcatg acttcccagc gcttggagtg tcgtcgagat agatatcgtg caagctatct
     3961 cggaagtcac ctgttcgtgc agcattcccc ttcggtcatt cggggagtat gttccaatgg
     4021 catggagact taagggggaa gtttgttaaa cacgggtctg aacaaggctt ctcatcagtc
     4081 ggcgacaaca aggacggcac cggtcacgct ggccgaactc tgggagcgga cggtacgcag
     4141 tcggcctagc agcccggcga ttgtctcgaa cagcgagatc ctgtcctacg acgaggtgaa
     4201 cgccagggcg aaccagctgg cccgactgct gctcaacgag ggggcggggc cgggccgtct
     4261 ggtggcactg gcgctgcccc gatccagtca catggtgatc agcgtgcttg ccgtggccaa
     4321 ggctggggcg gcgttcctgc cggtggatgt caaccacccg aaggagcgga tctcctacct
     4381 gctcgctgat gccgggcccg cattgctgtg caccatccgg ggcgctgtcc cgaagctgcc
     4441 tgctgacatc ggggtgccgc agctggtgct ggactcggcc aagcagactg ccacgctcga
     4501 cgcactgccc gacaccgaca tgactgagga cgaacgcggc ggctcactcg ccgcgacaaa
     4561 cctggcttac gtgatctaca cctcgggctc gacaggccga ccgaaaggcg tcgcgctgac
     4621 cagtgccggg ttgcccgcct tggccgcggc caaggtcgcc acgatgcagg tcactgagga
     4681 cagccgggtg ctccagttcg cgtcgccgag cttcgacgcc tatgtgaccg agctgctggc
     4741 cgcttttact gccggcgcca cattggtgct gccaggaccg gacgcactgg ccggtgaccc
     4801 gctggaaaag gcgttacggg atggccgggt cacccacgcg gtgctgccgc ctgccgcagc
     4861 cgcgaccgtg tccccggacg cggcgcagga cctacgcgtg ctggtggtgg ccggcgaggc
     4921 gtgcccggcc ggcctggtgg aacagtgggc gccaggacgc ctcttggtca acgcctacgg
     4981 tccgaccgag tgcaccgtgt gcgcgaccat gaccggcccg ctgaccccga cggacgaggt
     5041 cactattggc cggccgattc cgggcgtgtc tgtgcacatc ctcgacaacg cgctacggcc
     5101 agccgcggtc ggagagatcg gcgagctgta catcagcggt gccgggctgg cgcgtggcta
     5161 cctcaaccgc cccgacttga ccgcgcagtt gttcgtggcc aacccgttcg ccgccgacgg
     5221 cgaacggatg taccgcacgg gcgatctggc ctccatgcgg gccgacggcg acatcctgtt
     5281 ccatggccgg atcgacgacc aagtcgaact gcgcggattc cgaatcgagc tgggagaggt
     5341 ggagtccgtg ctcagccaac atccggacgt ggcacaggcg gtggccgtgc tgcgggcggg
     5401 cgcagccgag gggccgcagc tgctggccta cgtggtgccg acgcacgaca ccacgcccac
     5461 agcgggcgaa ctgcgtgagc acgccagccg cttcctgccc gactacatgg tgccgtctgt
     5521 ctacgcgacc atcgacgccg ttcctctgac tccgggcgga aagacagacc gagccaagct
     5581 gccggagccg atcaagacca cccggtccgc cggccaggga ccgcgcactc ctgccgagaa
     5641 gatcctttgc gatatcttcc gagacctgtt cgaccttgtc gagatcgacg ttcgcagcaa
     5701 cttcttcgaa atgggcggga acagcatctt ggctgtcgac ctcattcagc gagcgcagga
     5761 agccggcttg gtgctcttgc cgaggaccgt gctcgaccac ccgaccatcg agcagctggc
     5821 cgcgatagcg accctcgggg agtgagagat gagcacccgt cccacggtgt ctcccgacga
     5881 actcgaacag atcgacctgg cctcgccgat tctgcacgcc gagtacgagc tcggtgaggt
     5941 cttccgctac ctgcgggcca atcggccgat gtactggcag cagccacggg gtgagcagcc
     6001 cggcttctgg gtgatcagcc ggtatgccga cgtgaacgag gtgtacaagg acaaggcgca
     6061 cttcaccacg gagcacggta acgcgctggc gaccttgctg actggcggtg actcggcctc
     6121 gggcgccatg ctcgccgtca ccgacggtgt gcgccaccac caggtgcgca acttgttgtc
     6181 caagggattt tcgccgcaga tgctcgacct catcgccaac tcgctgcggg aaactgttga
     6241 cgggctgctg ctggcagcgc tggaccgagg cgaatgcgat gccgcgcagg acatcgcggc
     6301 gaacgtgccg ctgggtgcca tctgcgacct gttggaaatt ccccagacag accggaaata
     6361 cctgcttggc ttgaccgcgc acgcgtggag cacggactac gcggacgaaa ctcctgagga
     6421 gggctgggtc gccaagaatg aaatcctcct gtatttcagc aagttgctca aggagcgtcg
     6481 tggtggtgac cgggacgata tggtcagcct gctggcgaat tgccggatcg acggccatcc
     6541 gctcaatgca gccgagcagg tagccaactg ctacgggctg atgatcggcg gcgacgagac
     6601 cggcagacac gccatcaccg gcacgatcct cgcgttgatc gagaatcccg accagtggcg
     6661 cgccctgaag aacggcgatg tcgatctgaa gacggcgacc gaggaggcac tgcgctggac
     6721 cgtgccgtcg ctgcacggtg gccggaaggc aaccggagac gtcgtgatca atggccagca
     6781 gatcaaggcc ggcgatgtgg tcagcgtgtg gatctcctcg gccaaccgag atgaggccat
     6841 cttcgatgca gcggacgagt tcaagctcgc ccgcaccccg aacaagcact tcaccttcgc
     6901 ctacggctcg cactactgcc tcggccacta cctcggccgg atggaggtct acgccgtgct
     6961 cgacgggctg cgccggctgg taggcgacct ggagcagatc ggcgaagagc ggtggatcta
     7021 ctccagcatc ttgcacggga tgagctcact gccgatcagg atcacggtct gaaggccggg
     7081 gggacgtgca catgacgagc actgccgacg cggccaacgc attcgaggac gggcagggca
     7141 ccgagttctg ctcggatcgc cgggcagtcc gccttgcgta catcgagcgg aatcggttgg
     7201 cgcgccgacc gcggagcgca acccgatgac cgggcccgcc ggatccccag tggcttacga
     7261 gccggtcgcc atggtcaccg gagccggccg gggcatcggc gcggccacgg ccgagcgcct
     7321 tgccgcggag ggcatggcgg tgatcgtcgt ggaccgcgcc gaacaggaca ccacagccac
     7381 cgtctcagcc atccgcgcgg ctggcggacg ggcccgcggg atcggctgtg acgtcgccgt
     7441 agcccacgcg gtgacggccg cggtcgcctc ggccgtcgag gagttcggtc acgtcgacgt
     7501 gctggtgaac tgcgccgggg tcaaccagga tcggctgctg ctcaccatga gcgaccagga
     7561 gtgggacacg gtcctggacg tcaacctcgg cggcaccatg cgctgttcgt tcgcggtcgg
     7621 caggcacatg tgccggcagg ggcacggccg gatcatcaac ttcagttctg tggccgcgcg
     7681 cggcaatgca ggtcagacca actatgcgac cgcgaagggc gcgattgccg ggttcacccg
     7741 cacgctcgcg gccgaactgg gtcctcacgg cgtgacggtc aacgcgatcg caccgggctt
     7801 cgtggccacg ccgatggtgg acgagctgat cgaacggctc ggcgtggacc gggacacggc
     7861 cctgctggag gcggcgatgt cctcggccgt gggccggatc gggacgcctg aggaaatcgc
     7921 cgcggcggtg gcctttgtca cccggcagga atcgggctac ctcacagggg agaccatcca
     7981 cgtggaaggt ggtcggcgat gacaggagtc gcggtcgtgg ccggcggcag cgagcacacg
     8041 gggctcgcgg tcgcgctcag gttggcggcg gggggctttg acgtcgccct gctggacacc
     8101 gaattcacgg cggccgacaa aactgtcaga cggatcgagg agtccggcag gcggtgcatc
     8161 accgttgagg ccgagttgac cgacgccagg tcggtcggtg tcgctttcgg ccaggtgcgt
     8221 accgagctga gcagcccggc cgtgctggtc acctgcgtcg gaccagagcc ggtgccggac
     8281 gggttgcccg aggacgaatt cgcggacgaa cagcgctata ccctggtacg acggtcgctg
     8341 cgcccggcgt ttgtatgctg ccaggctggg gcgggccagc tactgcacca ccggtgcgga
     8401 cggatcatca tcgtcaccga gccggtagac gtcagcgaaa atgcctggcg cacctcccaa
     8461 cccgtgctgg ccggattgat cggtttcacc cggtccgcgg cgctggagct ggcgaggtcc
     8521 ggtatcaccg tgaacctcat cgcgcccgcc gactgcgcgg tcgacagccg ggccccggcg
     8581 caccaaccgg cagtcaacga cagcgcgggc tcctacgcgg acggggtcgc gcacgtgacg
     8641 gagtttctgg tcgacgagca agctgccgga atcaccgggc aggcgatcta cgtcgccgct
     8701 tccccagcgg aagtacctct acttcgcgaa aggtagtcac tggtggcgaa caaggaccac
     8761 ggaccggagc actacgtcac ccgcatcctc gccgaggcga cccgggacgg cgcgcaaccg
     8821 gttgtccggt ggcgggacac ggtaatcacc ggcacggagc tccaccgatc ggtacagcgg
     8881 gtcgcgacag cactgcgcga ggcaggtgtg gcacgcgacc acgcggtggc catcctgacc
     8941 caggtgaaca gcccatggat gctgatcgtc cgctatgccg cacacctgct gggcgcatcg
     9001 gtcgtgtaca tcaccggggc caatcacggc accgtgacgc acgacctgcc ggtgaccacc
     9061 cgggtccgga tgctgcgtga agcaggcgca tccgtactgg tgttcgacga gcgcaatgct
     9121 cagctcgccg agaccgtcaa cgagacggtt ccggacaagc tggtgctgtg cggcctcggt
     9181 catccggcgt ccggcacggt gaccgtcgac ggccggccgg tcgaggacgt gtcggtggaa
     9241 ttcgcgcccc aggcacccga gctggcgatg gtcctctaca ccagcggcac caccggtcaa
     9301 cccaagggcg tgtgcagact gttccggtcg tggaacgcgt cggtactcgg cggggccatg
     9361 catccccggc cggcttacct ggccatgacc gcggtgagcc acacagccgg attgatcgtc
     9421 gacatggcgc tggccgccgg cgggagcgtg ctgctgcgtg agaagttcga ccccggcgac
     9481 ttcctgcgcg atgtcgcgca gcaccggatc accgagacgg tcatgggcgt ggcgcagctc
     9541 tacgcgatcc tcaaccaccc cgatgtccgc accgcggacc tgtcctcgtt acgacacctg
     9601 ttgtacctcg gctgccccgc atcgccggaa cgcctgcagg aggcggccac agtgttgcct
     9661 ggcgtgctgg cccagtccta cggctccacc gaggccggtc ggatcaccgt gctccgcgag
     9721 gccgaccacg aacgtcctga actgctggcc accgtgggcc aggcgatgcc aggggtcact
     9781 atcgccatcc gcgacccgga aacaggacga gacctgccgg tcaaccagat cggcgaggtg
     9841 gtggtgcaca gcccggaagc catgggcggc tatgtcgccg atcctgagca caccgcgcgg
     9901 gtggtccggg acggctgggt gcataccggc gacttcggct ccgttgacga acgcgggtac
     9961 gtgcggctgt tcggccggat gcacgagatg gtcaaagtgc aggacacgcg agtcagtccg
    10021 accgaggtgg agaaggtact cgtcggctgt cccggcgtgg tggatgcgtg cgtgtacggc
    10081 caccgccggt cggacctgat cgaggaattg cacgccgccg tcgtgctcag caccgacggc
    10141 gccccgagtt tcgccgctct gcgcgaccac gtcgcgcagg ccatgacccc gacgcacgct
    10201 ccgatccggt tcgtccgctg gcggcagttc ccgatcaaca acaccgggaa ggtggatcgg
    10261 ctgcggatcc gtgaggtcag cgctgaggct cgcggtgaga gcccggacgt gctggtggac
    10321 aggtgaggtg agtcattcga tgagagtgct gttcacgagc ctgcccggta tcggccacct
    10381 gtttcccatg gtgccgctcg cctgggcgct acaggcggcc gggcacaccg tgctggtcgc
    10441 caccgaccgt gagttcctcc cggtggtgac ggcagccgga ctgcctggcg cggccgtgct
    10501 ggacccgatt gacccggtcg agctgttcag accggcaggc ccgtccggcg gtccggtgag
    10561 cccggctgag agcaccggcc accggtgcgc cgagagcggt atccgagcgc tgcccgccat
    10621 ccgtgcactc gtcgacgtgt ggcacccgaa cctggtgatc gccgaaccga tggagctggc
    10681 cgggcctgcc gcagcggcga ttgccggcgt gccctgggtg cggcactcct acggcctggc
    10741 cccgccccag cgactgctga gcgccgcggt tgcggccctg gacaccgaac tggcagtact
    10801 cgggctgtcc ccgttgggga gaccggcccg gacgatcgac gtgtgtcccg acagcctcca
    10861 gccttcggac gcggtggcga ccacgcccat gcggtatgtg ccctacaacg gcccggcctg
    10921 cgtgcccgat tggctactgg ccgggccgtc ggcccggccc cgggtatgcc tgaccctggg
    10981 cacgtccctg ccccggcgcg atccgcaggt cgcaccgctg tggcggctgc tgctggatga
    11041 actggtggct ctggaccatg aggtggtcat cgccatcgac gagcgccacc ggccgctgct
    11101 gggtcacttg cccggcggtg tgcgtgccgc gcggatcccg ctgtgcgacc tgctgccgac
    11161 ctgcaccgcg atcgtgcacc acggtggctc cgggagcacc atggcggcgg cgtcgttcgg
    11221 cgtgccgcaa ctggtcatcc cgcacttcgc cgaccatttc gccaatgctg agcgaatcac
    11281 cgcagtcggc gcgggcatga gcctgccgca cgacaccgat gacccagcgc ggatcgcagc
    11341 agcctgcgcg ctgatcaccg gagacggccc gtaccgcgcg gtctcaagcc aactcgccaa
    11401 cgagaacgcg agccgaccga aaccaaccga ggtggcccag gacctggtgg cactggccct
    11461 cgagcacgac acagtggaac acaatcgatg ggggaattac gcgagatggt aagtgggccc
    11521 accgagcttg agcacgtcct tacccgcctg gaaatactgc tgaacgacgt ctgggaccag
    11581 cgaccagcgg gggcggcgac gtctgccacc gcaccgctgg tgagcctggg ggtggactcg
    11641 ctcacgctcg cgctgctgct cgacaaggtg ggcagagaat tccacatcga ctggaccgcc
    11701 gacactcctc cgggcgcagc aagctcgcta cgttctatcg cggatcttgt tctgcgacgg
    11761 gacggtggcg gcgccaccgc tgccgaggca taggcgcaac agatgcggac atcaggtata
    11821 tacgtggccg ggatcggagt cttccggccc aagacggaga gcgtcgatgt cgcagtgcgg
    11881 caggggctcg tctcgaagta cgctgctgac gcctccggga tcactggcgt ggccgtcgcc
    11941 ggcgacgtct cccctcccga aattgcgctg atcgctgcac aacaagcact caagagtagt
    12001 gggctgagcg ccgatgacat cgggctgttg ctctgcacag gggtttggca ccaaggaccc
    12061 gacgggtggg gaccgcagta ctttctccag cgacacctgc tcggtgacga tctgctggcc
    12121 gtggaactca ggcatggctg caacgggact ttcagcgcat tggaattggc cgtcccgtat
    12181 ctgaggtccg cacctcacgt tggcggggca ctgatcaccg ccagtgacaa ttttggtacc
    12241 ccgctgatcg acagatggaa tcccggcgaa gggctggcct ttctgggtga cggcgcgggc
    12301 gcggtggtgc tgggcacttc tccggggttc gcggaactgt tgtccatatg caccgcttcc
    12361 ttctccggga tggaggaggt ccaccgggcc ggcgagccgc ttttcccgcc cggcgccacc
    12421 accggtacct ttctggacta cggtgccaga gccgcacgct tccagcagaa ggcgaccgat
    12481 gacggcactt gggtgcagtt cctcctgggc caccagaagc acaacctgga gtgcgtggaa
    12541 caggcactcc acgaggccgg tgtggacgcc cgcgacatca agaccgtcgt gatccacagc
    12601 atgccgcgac aggctgccgc ctcctacctg aagatcctcg gtttctcgct ggaaagctcg
    12661 acctgggagt tcagccggac aaccggccac ctcggggctg gcgaccatct cgctgccctg
    12721 caccacctct tgtcgacggg caaggtcggc cccggcgaca acctgctgct ctgcggttcc
    12781 tcgccgggcg tgacatacaa ggcggccgtc atccgaatcc tcgacaccgc cgccttacgg
    12841 aaccaggagg ctcggcccga tggactttga cctcagccca cagcagcaac agcgggtcga
    12901 ccacattcgc gcaggggccg gcaagctgcc gtccgcgaaa cccgatggcg tcgctggaaa
    12961 ggacagctgg ctggctgcgg ccgaactcgg catgaccggc ctgtgcctgc ccacggaaca
    13021 cggcggcggc gggctcggcg ccctggacac ggcgctgtgc ctcgaagcgt tctgcgccgg
    13081 cggcgcggac accggcctcg ccttcgggat cgccgcacac ctgctcgcct gcggtacggt
    13141 cctgaccgac cacgcgggcg acccggtgcg ggccgagctg ctacgcggac tgacctcggg
    13201 aaccgtgatc gccgcgaacg cgatgacgga ggacgacgcg ggatcggacc tgagcagact
    13261 cgccacgaca gccgtagccg acagtgacag ctacgtcctg aacggaaaga agtccttcgt
    13321 cagcaacgcc ccgctggcag acgtcttcat cacctacgcg gccaccacac cgagcgccgg
    13381 ttatctgggg atgtcggcgt tcgccgtccc ccgaacgctg cccggcttgc ggatcaactc
    13441 cccactggcc aagatggggt tgaacggctg tgccgccgcg caggtcgagt tcaccgactg
    13501 caaggttcct ggccgctatc tgctgggccc cgagaaccag ggcaacagca tcttccaacg
    13561 ctccatgatc tgggaacgcg cctgtctgcc cgcgatctac ttgggtgcga tggaggttca
    13621 attagcccag tgcgtggacc atgcccaaag tcgccggcag ttcggccgca gcatcgggac
    13681 ctttcaggcg atctcccacc ggctcgccac catgaaactg aggctggaaa ccagccgcct
    13741 gcttctctac cgcgcgtgct ggtacctcga ccaaggccgt tcggccgtgg aggcggtcgc
    13801 attggccaag acggcagtcg ccgaagccgc cgtagccaac gcgctggacg cggtgcaggt
    13861 gttcggcgcg cgggggtatc tggccgcgga cggcatcggc cagcagcttc agaacgccat
    13921 accgctgaac atcttctcgg gaacgacgga gattcaacgg gaggttgtcg caaggagcat
    13981 ggggttatga gcggtcgggt cgaaagctgg agtagcaagt gatctctgac ggtaggacca
    14041 aagcctttcg tgccgtcagc cgctcacttg accaaccaac ctttcctact gcgcacagga
    14101 gccgaagcat gagtgatcgg cgcggcctcc acgacctgct tgccgcctcc gcagctcgca
    14161 cgcccaacgc tcctgcggtt atcggacccg ccggttcgat gagctacgga gaactcgacg
    14221 aacgagccaa cgacctggcg ggcaggctgt ccggtcgtgg aatcgaaaag ggggatcgag
    14281 tgctgatctg gtccccaaag tctgccaacg cgatcgccgc tatgcaggcg gtcctgcgcc
    14341 tcggtgcgat ctacatcccg gtcgatcccc tcactccccc cgagcggttc gcggcgatcg
    14401 cgcgcgagtc cggggcgctc gccctgtgtg ctccggacga cctgtccgcg cgggttccca
    14461 gcccccttcg cgaccgccta gcgtgtgttg atctcgacgc cgcgccggtg cccaacgccc
    14521 tcccgactgc accggtgaac acgcgcgttg aaccagacga tctcgcctat atcctctaca
    14581 cctcgggttc gaccgggaca cccaagggcg tctgcgtcag ccaccgcagt gccctggcct
    14641 tcatcgattg ggccgttgcg gaactcgctc ccggcccgca ggaccgcttt gccaaccatt
    14701 cagggctttc gttcgacctc tccgtcctcg acctctatgc agccttcacc gtgggggcgg
    14761 ccgtgtgtcc gatacacgcc gagttcgcgt acgccccgga acggctggtc gagttcctgc
    14821 accgcgagcg gatcagcgtg tggtattccg tgccttccgt tctgattctc atgctgcgtg
    14881 acggcggtct gctcgaccgg cccgcgcccg agacgctccg cgcgctactg ttcgccggcg
    14941 agccgtttcc gatcggctat gtccgagccc tcgccgcctg gtccgacgcc cggctgctca
    15001 atctgtacgg acctaccgag accaacgtgt gcacctatca cgaggtccgc cccgcggacc
    15061 tcgcgcgcga cctgccagtc ccgatcggaa ggccgtgcag cggcgaccgg gtctgggctc
    15121 gccgccccga cggttcggaa gccgaacccg gtgaggaggg cgagctggtc gtcagcgggc
    15181 cgacagtctt tgccggttac tggggccggc agccacagga gggcccctac gcgaccggcg
    15241 atcgagtcaa ggtccggcca gatggttcgt tcgattacct agggcgccac gacgacatgg
    15301 tgaaaatccg tggacaccgg atcgaactcg gagacgtggt cgccgcgctg aactcccacc
    15361 caggggtcgc cgaggccgcc gtcgtcgcgg tgggcgaggg gctggaccgg aacctggccg
    15421 cgttcgtgat ccgaagccag ggaagcagtt ttggaaacgt cgcgctgcgt cgacacctgg
    15481 ccgacagact cgcaccccac atgatccccg gtgacatccg cttcgtcgac cagctgcctc
    15541 acaacgatcg ggggaagctc gacctcgcgg ctctgcaaat accactccac ggcgcacaga
    15601 aagttcaagg gtgagaaatg acgacccaga cccgagaaga catttcgtcc gagttgctca
    15661 ccttcatccg cgagagcttc ctggccgggg acccagaggg tgagctcgac gcggacaccc
    15721 cgttgctcga actcgggata ctcaactccc tgaacactgc cactctgatc gcgcacctcg
    15781 gggagaggtt cggcgtccac gtgccattga tggacgtcac cgccactacc ttcaagtccg
    15841 tgcgcaccct gagtgagatc gtgcacgaga gcctgtcgcg aaagtgaata ctgtcgtcac
    15901 cgccaacaaa tagtttggat gtcccagtga aattgaacgc ggacatgttc ctgctacatg
    15961 cgcccagcgt gtacgacttc cgggaccgtg acgacatcct gttcgcctac ctgagtgaca
    16021 gcgacagcgt caacgtcacg tccgtctacg agatgtaccc catcggctgg ttctcgatca
    16081 agcaacagct ggccgaccac gacttcgact gccagatcgt caacatcgcc tccctgatgt
    16141 tgaagcaccc ggatctcgat gtcgagcgac tgatcgagcg gctggaagcg ccggtcttcg
    16201 gcttcgacct gcactggatg acccaatgca acggcgccat cgagctggct gaagtggtaa
    16261 agcgaattca tccagagtcg ctgatcgtct tcggtggcat ctcggcgacc tactttgccc
    16321 gggaactcat ccagtacccg caagtggacg tcgttgtcca gggctacgac actctcgccc
    16381 ccatcaccca gctggtcgag gccgtggtcc ggggtggccg agacttcagc tcgataccca
    16441 acctcctcta caagggtaat gaccgggtcg agaccacagg attcagccac aaacccgcca
    16501 cggactacaa caacgtcagg aatgactggt cctactacca gaacacgcct gtgacaccgc
    16561 ttgccagcaa gctgatcatg acgctgccga acaccgggtg cgcccacgac tgcggctggt
    16621 gcggcggctc ccgcttcgcc tatcgcaaca tcatggaggt gggcaccaaa accctggtgc
    16681 agaaggacaa cgacctgatc gtcgaagagc tcaagacgat gggcgaggcg gccaaacaca
    16741 cctccatcta cgccctccag tgctactcag agggcaaagc aaggatgcac acgtacctcg
    16801 acgccgtgca cgacctcggg taccggagcg tcttcttcga gcaattcaac ctgacgcccc
    16861 acgacacgct gaagaagatg ggcacatcca cagactcgta catcatgctc tctcccgagt
    16921 cgcacgaccc aaagatcagc agggcagccg gtcgcggcac atacacaatg gccgagatgg
    16981 aggaatggat tccacgcgcg ctggatgccg gtgtcaaggg cgtgatgatt tggtttttca
    17041 tcggcatgcc atatcaggac aggcagtccg tgcgcgacac ggtcacctac tcggagcacc
    17101 tgatccgcaa attcgcgggg cagccggtcc tgccgctcat ctgtcccatg gtgcccttcc
    17161 tggacccggg ctgccgcttc ttcgaggagc ccgacaagca tggctaccga atccaccacc
    17221 gcacgctgga ggaacatcgg caggccatgg tcgaaccgct ctggtaccgc cggctgaact
    17281 acgagaccaa gtggttgagc cgacgcggca tccaggatgt ctcctatgag gcgatcgagc
    17341 ggttggtgag tatcaagggc gagcacggtg ttttgtccag cgtgttttgc gaagcggtgc
    17401 tgaagacaat tgaccagacc aagcggctcc ttgcggagat ggatcacgct ctctccctgg
    17461 acggccggct tcccgcaacc ctgcgagacg agatgcgtgc ttacaaccgc aagatcctcg
    17521 cttattccag cgaccagatc ctgcccatac cccgcccctt cggcggacgc tggttcgatg
    17581 acgtcaccgt gcctgaggag atgatccgcg agctgtcgat gaccccgtga acccacggag
    17641 acggcagact ccccaacagc agagaggacc aactgagcat ggcgaatgac aaaccggtgg
    17701 tgcagagcct gaaggtgcct ggcgcgcgct tgcactacga gatccaaggc gcaggtcccc
    17761 tgctcgttgt ggtcggtcta ccgatgggct gcaaggggtt cgcgccgatc tcgcagctgc
    17821 tggccgagca cttcacggtc gtgaccttcg acccccgtgg ggtcatcggc agccctctgg
    17881 aagacccaac ccaggaggca gagccagagt tgatggccga cgacgtgcac cggctcattt
    17941 cgacgctcga cgccgggccg gtgtacttgt tcggcagcag cggaggcgct gtaaccgcgc
    18001 ttgtgttggc tgcccagcac cctgaacagg tcagggcgct ggtcgcgcac gagcccccgc
    18061 tgctcgagtt gttgatcgac cgcgaacaga tgcgcgccgc catcgatgag atctgcgacc
    18121 tttaccgtga gaaccgcccc gtggcgttgc agaagtacct cgccctggcc aacatccgcc
    18181 tccaccggcc ggcccagcag ccgcccgaac cgaattcgtt caccgacccg gaagacgtgt
    18241 ggaccatcct cgatcggctc tttcatcaca cccttcgccc aactacccgc taccgacccg
    18301 acatcaacgc gttgcgcccc atgggcgacc gaatcgtcat cgccggcgga tccacggccg
    18361 aggggtcact cttccaccgc accgcggtcg cgctcgccga tcagctcggc accaaactcg
    18421 ttgagtttcc cggcgaccac actggcttcc tgaccgagtc ggagtccttc gcccagttgc
    18481 tgttcgaggt gctcacaaac gcacgtcccg cataacggtg cttgtcggag tgctggcgca
    18541 ccacgcacac tctctgccag gatttacacg tccgctcgta cctaaccagc actcacgccc
    18601 acggaatccg cgccatcgac gccattcacc tccggaacgg aagcttggct atctgtattt
    18661 ccgttacccg gaggttcgca aagggtcgcg gatcgcagaa accgtgggta gactgattgg
    18721 cgatttatcg tcagcggttg gaggaagtag cgtgtccgaa aaccaggaat atgacgtcat
    18781 tgtgatcggc ggaggccccg gagggtcgat ggtgagctca ttgcttgccg acgggggtaa
    18841 gaaagttctg gtcctcgaag ttgcgaagtt ccctcggtac cacatcggcg agagtctcct
    18901 cttaggcacc gtcgatctgc tcgacaagat cggcgtccgg gaaaagctcg aagccggtga
    18961 ctacattaag aagtatggcg tcgagtgggt gtggggagag caacgagagc cctggaaggt
    19021 tgatttccgg aacgcggtgt ccgtgaccca tgactataca tatcaggtcg aacgcggtcc
    19081 gttcgacaag atgttgctgg acaacgcgcg ggagcacggg gttgatgtgc gcgagcagca
    19141 cagggtcaca aacttctcca tcgacgacaa cggccggtcc accgtaaatt accggcgtac
    19201 cgacaccggc gagaccggca ctgccacggc ccgttggctg gtcgatgctt ccggccaggg
    19261 cggcctggtg accaagcgcc tccacaccca ggaatgggac ccgtatctca agaatatggc
    19321 ggtctggtct tactggaagg gagtgaagcg ctccgaaggc gaagacgccg gcaacatttt
    19381 tctgcccacc ttcgatgacg gttggtggtg gtgcattcca ctgcgagatg acatcacgag
    19441 cattggagca gtggtcgacc gcgagtccct caatgcgctg aagtccacgc gtgtgcggca
    19501 gtactacctc gacagcatcg agaaaacgcc cgaactcgcg agccgaacgg aaaacgccga
    19561 actcgtcgat gacatgcacg tccagcgtga ctggtcctac atttacgacc gtttctgcgg
    19621 cgatggctac atcgcgatcg gagacgcggc ctgtttcatc gatccgctgt tctccactgg
    19681 tgtccacctt gcgatgctga gtggctttct tgctgcgacg gtcgtcaata ccatcctcga
    19741 caagcccgaa ctggatactg cgcggatgct gcagttctat gagggcgcct accgcaaaga
    19801 attcgcgcga ctgcgcgacc aagtatattt cctttacgcg ggcaacaagg gcagcaagga
    19861 atcgtacttc tggcacgcgc gcagccattt tggcgtgccg tcgatcgagc ccgagaaggc
    19921 cttcgtctcg ctcatcgcgg gcgccttcgc gcaccgcgcc tggtacaacc actatgcaaa
    19981 acatcttgac gtatcagcgg acctcaaaaa gtcggtcgag agcatgttca atggtgctgg
    20041 cattgatttg gacaccccgc tgatcgccag tgcctgcgga tcggtggtga acgacttcgc
    20101 agtcgacgga cgctatctcc gcgaagcgcg ctccctcgtg cacacaaatg gtgcgtcgat
    20161 cgcgtataca ccggccgtca gggcggcagt tgaacacgcc gacggaaaac gcacgggccg
    20221 cgagatcatc gaaataatca ccgaccgcgg aatcgacagt gaggatcgcg cccgaagcat
    20281 cgtgcacgaa gtcatcagct acggattcgt agaacccaag gcgtaagcgc ggtacgtgac
    20341 gaggacttct cgcccgaagg cttccagtac tcaggttgaa tctgcgatat ccggttcgtg
    20401 gatcagcccg ttgagatcca gaccggtggc cggcagacag ccgacgatca ggtgtggtcg
    20461 gctccagatc ctgtcgcact tcgttcggtg atgttcggtg gacgctcgcg tgtggtggta
    20521 aatcggccgg gcggccagat ttcgctttga tcgaccacgt agtcccgcac gcattcatgt
    20581 catgcacctc cggcgcaact ggccaaccgc atttcctcgt caaccttctg agtcgaggca
    20641 ctggacccga atggaagtga cacctatcgt ggtcagcgtg gcagacaatt cattgcaagc
    20701 tcagcccgaa ggacctacac aaggcacaag cagcggctca tggctgtatc tgaacctcat
    20761 gaagaaggtg ctggccggga ctgtgtacga ggatcccgca caccggcaaa acttctctca
    20821 tgacgatgca acgtaccggg aagaggtccg caatgagggg cgggactggc cggccaacgc
    20881 gcacacgatg atcggaatca aacgcctcga aaacattcag caatgtgtcg aagacgttat
    20941 tggcaacaat atccccggtg acctcgcgga aaccggggtg tggcgtggtg gagcgtgcat
    21001 ctttatgcgg ggaatcctgc gcgcccacga cgtgcgcgac cgcactgtgt gggtcgccga
    21061 ctccttccag ggcattcctg acgtcggtgc ggacggctat cccggtgacc ggaggatggc
    21121 gctgcatcgg cacaatgccg tgctcgcggt gtccgaggac gaggtccggc gcaacttccg
    21181 caactacgac ctgctcgacg agcaggtccg gttcctcccc ggctggttca aggacaccct
    21241 gcccactgcg ccgatcgacg cgctcgccgt gctgcgaatg gacggggatc tgtatgagtc
    21301 tacttgggac accttgacca atctctaccc gaaggtgtcg gtcggtggct acgtcatcgt
    21361 ggacgactac ctgatgtgcc cgccgtgcaa agacgcggtg gacgaatacc gcgcgaggtt
    21421 cgacatcgcc gacgaactga tcaggatcga ccgcgacggt gtctactggc agcgtacccg
    21481 gtagtccaca gcgagttgat caatgcggga tgctggtttc ggttgccggg catggtgatt
    21541 gacgggtttt cgcgccggat cacggggtcc cacgcacccg agatgtggtc ccggtgggag
    21601 gcgtggctgg atgcctcggg catgctggac caccgagcgg ggacacgaga acaggccgcc
    21661 gcgcagcggt tgatggtgcg tcggccgcgc ccgtcgacat cggtggcatc ggtagcgcct
    21721 ggccggcgtg cgggaacggc agcttggcgg agtccgcgcc ggcggtgagc cggccgccga
    21781 tcgccgcatc gagcgcatcg ccgtcgatgc gctgcagtac ccggcgcgca gtcacctcgc
    21841 tgggcgcccg gtagggccgg tgcggttcgc gcagcatggc cccgcagcgg agaaagagct
    21901 gttcacaggc gtcgtcggct cactcgggga tcgcggtgag ggacttcgct cctaccagga
    21961 ccgcgcaggc ggccagggcc gggacgtacg gcagcgggtg acggcgaccc cggtggcggg
    22021 ggtcgggcag gcgggacagc cgggcccgta ggccgggcag ttcttcgggc gggccggacc
    22081 ggagccggcg agttgaccca gcccggcggg gatggctgat gcctgcgtgg caggcacgga
    22141 attccgtcgt ggtgatcagc gaactcgaca ctccatggtc accggaagct gtgcctgcgc
    22201 gtgtacctgc cgatccatca ccatcacggc cgagttgccg tatcaggccc ataccggctc
    22261 tgtcgcaccg accgccaaaa cgatggagcc ctgcacccac ttttccgaca ggaggtcccc
    22321 tttttgggct gcgcggtgat ttgatagtga tagagaccga cggtctgtgg gcgctcgtgt
    22381 gagagcgcta ctcatggcgt gttgcgccgt aaatcccatg gaaggccctg gcctgagcga
    22441 tttgccgcca tgcccatagg cggccaggac tgacggagga agtcatgccc gctctcccga
    22501 tagatcaaga attcgactgc gaacgcttcc gtgccgatat acgcgctacc gccgccgcga
    22561 tcggcgcgcc cattgctcac cgtcttaccg acaccgtcct tgaggccttc cgtgacaact
    22621 tcgcccaggg cgccacctta tggaagacca ccagtcagcc tggagatcaa ctgtcgtacc
    22681 ggttcttctc ccgcctcaag atggataccg tcagccgtgc catcgatgcg gggctgctag
    22741 acgccgcaca tccgaccctg gctgtggtgg acgcctggag cagcctctac ggcggcgcgc
    22801 cggtacagtc gggcgacttc gacgctgggc gggggatggc caagacatgg ctgtacttcg
    22861 gcggcctgcg gccagccgag gacattctca ccgttcccgc tctgccggcg tcggtgcagg
    22921 ctcggttgaa ggacttcctc gcactgggcc tggcacacgt ccggttcgca gcggtggatt
    22981 ggcgccacca cagtgcgaac gtctacttcc gcggcaaagg tcccttggac accgttcagt
    23041 tcgcccgcat ccacgccctg tccggcagca caccaccagc tgcacatgtg gtggaagagg
    23101 tcctggcgta catgcccgag gactactgcg tcgccatcac cctcgacctg cacagtggcg
    23161 acatcgagcg ggtgtgcttc tacgccctga aagtccccaa gaacgcgctg ccacgcatcc
    23221 ccactcgcat cgccaggttc cttgaggtgg cgcccagcca tgacgtggag gagtgcaacg
    23281 tcatcggctg gtcgttcggc cgcagtggcg actacgtcaa ggccgaacgc agctacaccg
    23341 gcaacatggc cgagatcctg gccggctgga attgcttctt ccacggtgaa gagggccgcg
    23401 accacgacct gcgcgcactt caccaacaca cggaatcgac catgggaggt gcccgatgag
    23461 caaggctttg gcgaacatgc ccggagacga ctatttccgt cacccgccgg tgttcgacac
    23521 ctacgccgaa caccgcgcct atctcaaatt tcggcacgcc gtcgcgctgc ggcacttcgc
    23581 ccgcctcggt ttcgaccagg acggcctcgc cggcttgatc accgtcgccg atccggaaca
    23641 cgccgacacc tactgggcca atccgctggc ccaccccttc tccaccatca cgccggcgga
    23701 cttgatccgt gtcgacggcg acagcaccga gaccgtcgac gggcaacgcc gcgtgaatat
    23761 tgccgcgttc aacatccacg ccgagatcca tcgggctcgc cccgacgtcc aggccgtcat
    23821 ccacctgcac accgtctacg gccgtgcctt ctccgccttt gcccgcaagc tccccccact
    23881 gactcaggac gcgtgcccgt tcttcgagga ccacgaggtg ttcgacgact acacgggtct
    23941 ggtgctcgcc aaggacgacg ggcgcaggat cgccaaacag cttcgcgggc acaaggcgat
    24001 cctgctgaag aaccacggtc tggtcaccgt cggagaaaca ctcgacgccg ccgcctggtg
    24061 gttcacgctc ctggacacct gctgccatgt ccaactgctg gcagacgcgg ccgggggcgc
    24121 ggaaccgatc cccgcggagg tggcgcgcct gacaggtcag cagctcggct cacacttgct
    24181 gggctggaac agctaccagc ccctgcacga ggcaaccttg gcccgcaacc ccgacctcgc
    24241 ggccatggcg cctgcactcc cgccccaaac gcccgccctg gcaaggtagg gctgccgacg
    24301 tcacattgcc cgggccgaac tacgcggtca gcccggggga ccgcaccaca gaacgtaagg
    24361 acgccggtga gcgtggagaa tccaggctac gagcacggtc tgcccagccg caggcgagtg
    24421 tcaatgcggc gaggactctg ggccggccgg ggggcttgta aatcgcgatg ccgcaggatg
    24481 gggtagcgca gcgtcttccg cgtggccctg gtcatctcgc tgtccagggc gaggagttgg
    24541 agtcagcagc tgagatcggc ggcaggggtg gtggcggtga gccaggcggc gttgacgtcc
    24601 aactcgggcg agggcaacag gccggtcccg gaagccgcgt agctggggtg gaggggttcc
    24661 ttgcaggcga tcacccggtg gtgccggcgg ccggccaggc aggtcgccga gcagagcggt
    24721 gatgtcagcg acgaacgcgt tctcgcgtac gccgccatct gggccgccgc tggccggccg
    24781 ccacaggccc tgcttgtcgc acatctcgat ggcggcctgt tcgtgtgcgg tgaaggccca
    24841 gccgacggag tactcccagc ggaacgtggg gctctgacgg tcgcccgcgc aggcgatcca
    24901 gtcgatcagc tggtgggaga agcccgggaa agcccctgct cgtcggcttg gttcagcgcc
    24961 cgccatacgg tggagtgaga ggcgaccgcg ccgaagaccg gccgcgtcgg gccagcgccg
    25021 tcgacagcgc cccggtcagc ccaattcaca gtgaaacaac gaaaccaccc actgcctcat
    25081 tcgtcttgac aaccaacgcg gcggagctgg aagctcacat ggtgaatcgg tggttagtta
    25141 ctggtgcggc aggaatgctc gggcgagatt tagtgggggt tttgcaaggg ttgaacgaat
    25201 cagtggttgc tgtcactcga caggatctcg acatcaccga ccgcttttca gtccgagccg
    25261 ttgtctccag gtatcaaccg acgacgattg tcaattgcgc agcgtggacg cgattccctg
    25321 aagcggaggt cagtgaatcg gaggcccttc ttatcaacgg aagaggggtc agagagcttg
    25381 cttcgatatg cagcgatcga tcgatacggt tggtccacct ctccactgat tatgttttcg
    25441 atggcacgag ttgccagccc tatgccgaaa gtgcggccac cagtccgatc aacgcgtacg
    25501 gccggacaaa gctggccggc gagcaggctg tgctcgagtt gctgccagac gacgggacga
    25561 tcgtacgaac cgcctggctt tacgggcgac atggcacgaa cttcattcgc aagatggtcc
    25621 ggctggagca gatgcgcaag acggtggacg tggtggacga tcagtggggc cagccaacgt
    25681 ggaccgtgga tttggcacaa cagatcgtgg cactcgttcg gcagggcgca tccggcgtgt
    25741 tccacggaac gagctcaggt gagaccactt ggtacgacat cgcccggatg gtcttccggt
    25801 tgctcggtgc ggatcccgga cgcatccgcc cggtgcgcag cgaccaagtc gccggtggcg
    25861 aactgcggcc ccggtacacg gtgttggggc atgctgcctg gcgcgaggtc gggctgacgc
    25921 cgattcggca ttgggctacc gctctgacgc agtcgtttcc ccttctggtt gacggtgaat
    25981 cgtaatattc ctagagtaag agaaaggaga tgccgcggat gcgacttctg gtgacgggcg
    26041 gtgccggctt catcggctcg gagttcgtcc gggctacctt gcgtggcgtt ctgccgggtt
    26101 catcgggaac tcatatcacc gttctggaca agttgacgta ttccggcaat gagctcaacc
    26161 tggcaccgat cgcggacctt ccgaattacc ggttcgtgca aggcgacatc tgtgatcggg
    26221 gcctggtaga cgatgtggtg gccggacacg acgcgatcgt gcacttcgct gccgagacac
    26281 atgtggatcg ctcgatcgac agtgccgcat cgtttgtccg tacgaacgca ctgggcacgc
    26341 aggtgctgct ggaagcagcc tcccgtcacc gacttggacg gttcgttcac atctcgaccg
    26401 acgaggtgta tggatcgatt cccgagggcg cctggaccga ggtgtccccg gtagccccga
    26461 acgcaccgta cgcggcagcc aaggcggcgg gagatctgct ggcgctggcc tggcaccgga
    26521 cccggcggct cgacgtagtg gtcaccagat gcaccaacaa ttatggtccg taccagtatc
    26581 cggaaaagct gatcccgctg ttcacgacca atatcctgga cgggcagcag gttccggtgt
    26641 acggcgatgg ccgcaaccgc cgtcagtggc tgcacgtgtc ggaccactgc cgcgccatcc
    26701 agttggtgct cctcggtggt cggcccgggg aggtttacca catcggcggt ggcatcgagt
    26761 tgaccaacct cgaactggcc gaacacatcc tcgctgcctg tggtgtcggc tgggacatgg
    26821 tgcggcatgt tccggacagg ctggggcatg atctccgcta ttccctggaa accgccaaaa
    26881 ttcgtacgga actcggtttc tcacctcgtg tcgcgttcgc ggaggggctg gcggagacag
    26941 tggagtggta ccgcactcac cgtggttggt gggagccgct caagaatcct gacaaagcga
    27001 caggttcacc cagcgacgcc ggcagatgat ggcgcaacca ggcggcggaa cacttcgtgg
    27061 atgtcgtcac ggatctccca gcggatgcgc cgcggtcggc ggcgtgagtt gggtgatgct
    27121 gccgccggtc agcgacacct gctctttggt caacctattc caagattcca agatccattt
    27181 tgttagcagt tcttgcaggt gaggaatcga ctgcccaaga ccggcggttt gcatcccgtg
    27241 agggggagga agagttgcag gacatcgtgc ggcccatcaa caagtgccgg gtgtgcgggc
    27301 acaacgattg gcttgatgtg gtctcgttcg gatcgacacc actggccgga aacctgctcg
    27361 gcaaggaaga cgccccaggg ggcgagactc tgttcccgct ggatgtcgtc gtgtgccgga
    27421 aatgctggct gatgacactg cgtcatgtca tcgaaccgga tgtccttttc gggcactatc
    27481 gttatgtcgc ctcggacgca ggctcgatca tccagcacat gcggcagctc gtcgaactgt
    27541 gtatcgggtg gatcggtctg accgatggag atctcgtcgt ggagttcggc agtaacaccg
    27601 gcgctcacct gcagctgttc cagcaggccg gcatgcgggt gcttggcgtt gatcctgcgc
    27661 gcaatctcgc cgacatcgcc aacggccgcg gcgtggaaac gattcctgct ggtttcatca
    27721 ccgaagtcgg ccaggagatc gcgagtggac atggtccggc gcgactggtt tacgggcgcc
    27781 aatgtttcgc ccacatccac gacattcacg aagtcctcaa cggagtctcc gccctgctgg
    27841 cgcctgatgg cctgttcttc gtggaagttc cctatctagt cgaactgctc gcaaacaatc
    27901 agttcgacac catctttcac gaacaccttt cctacttttc gcttggctcg ctgtgcaggc
    27961 tgttcgagtc gcacggcctt cgcgtcgtgg acgtacacac agccgatgtg cacggcggct
    28021 cgatcgtggt cttcgccgcc ccgaccaccg ccggctatga ggtgcggccc gctgttgccg
    28081 agatgctcgc ggaagaacga agccagggca tcgcagagga gggaacatac cggaaattcg
    28141 ccgagcgtac ggaacgagtt cgcgcacaga tccgagaact ggtatgcggc gtggtggcag
    28201 agggcaagtc agtggctgga tacggcgcac caactaaagg cagtgcactg ctcgccgcat
    28261 gcgggctggg gcatcaggag atccggttct gtagtgacac aacagctctg aaacagggaa
    28321 aaatcctacc agggtccaga attccgatct ggtcaccgga acaggcaggc gaccatgtac
    28381 cggactacta cctgctgttg gcctggaact acgcgccgga gatcatcagc aaggagaagt
    28441 cgtttctgga aaacggcggc cgttttattg ttcccatacc cgaaccacgc gtgatatcgg
    28501 cggagtcggc gttgtgacgt ggccacggtg tcggctgcgg tgatcccgtt ccacgtggcg
    28561 agaaggtcgg aaggggggac gaagggacag ggctgccggt gcatttcggt gtccgtccct
    28621 tggacgcgat gcggggaatc cttcttgcgg gcggtaccgg ctccaggctg tggccggtca
    28681 cccgggctgt ttccaagcag ttgataccgg tcttcgacaa gccgatgatc tactacccgc
    28741 tgaccacgct gatgatggct ggcatacggg agatactggt gatcacgcgc cccgaagacc
    28801 agcgccagtt ccgccatctc ctcggcgacg gctcgcaact gggcctgcgc cttgagtacg
    28861 ctgtccaaga gcagcccgag ggtatcgcgc aggcgtttgt cctaggtgcc gagttcattg
    28921 gcgaccagtc ggtggccttg gttctcgggg acaacatctt ccatggcggg ggcctgggga
    28981 ctcggctgcg tgagtacagc gaccccgtcg gggggcggat ctttgcctac gtcgtcgccg
    29041 accccacagc ctacgcagta gtggagttcg acgaggccgg tatggccgtc tccatagagg
    29101 agaagccggc cgatcccaag tcgcggtacg ccgtgccggg gttgtacttt tacgacaacc
    29161 gggtggtgga ggtcgctcgc ggcctggtgc cgagtgagcg tggcgagctg gagatcaccg
    29221 ccgtcaacga aacgtatctg aggtggggtc agttgcgggt gaccgcactc gaccggggta
    29281 ccgcctggct ggacacggga acgttcacct ccttggtcca ggcatcggag tacgtgcgtg
    29341 tggttgaaga acgacagggc ctcaagatcg gctgcgtgga agaggtcgcc tggcgctgcg
    29401 gcctcattga gaatgaccag ttgcgggaac tcagccgccc attgctcaag agcggctacg
    29461 gccaatatct cctcgacctg ctcgccgaga gggagttgaa ggagttgaag gtgtcgtgaa
    29521 actgcgcccg ctcggtatcg agggtgtctg ggagatcacc cctaggcagc acgccgatgc
    29581 gcgcggggtc ttcctggact ggtactgcgt cgaccggttt gccgcagagg tcggccgccc
    29641 actgcggctg gcccaggcca atctgtcggt atccgctcgc ggcgtgctgc gcggcattca
    29701 cttcgccgat gtgccgccgg ggcaggccaa gtacgtgacg tgtgtgcgcg gcgcggtgtt
    29761 cgacgtggtg gtggacctac gcgtcggctc gtcgacttac gggcgctggg aaggtacccg
    29821 actcgacgat gtcagccgtc gtgccgtcta cctctcggaa ggcatcggac acggcttctg
    29881 cgcgatctca gacgaggcca cgctgtgtta tctgtgttcg cagacctaca acccggcatc
    29941 cgagcatggt gtgcacccgc tcgatcctga attggccatc aactggcccg ccgggacccc
    30001 gctgctctcc gcccgtgacc aggacgcgct cttgctctcc gaggcccggg attcgggctt
    30061 gttgcccagc tatgcggcct gtcaggcgtt aacggcgttg actcgtcgat gatggtccgc
    30121 ggcgtgccga cccgcgggtc ggcacgccgc ggcagcgggt cgtggaagtc gcgtctggtg
    30181 gcggggaccg aggccagcga cagggcgccc ccggccgtgg ccatggccga gccggtggca
    30241 gccgggtggc tacgcgcggt ggccgccgaa ctggcccgaa ggcaacggga cgtgatgcgg
    30301 gtacggcgcc ggaccatgcc ggcggagaac ttcctcagct accgcaagct gtcggaccac
    30361 tggctgcaat ttcccaacgg cgacctcctc accccacgcc tccggtatcc ggtgcagcgt
    30421 cgagcagccg tcgtccggct cattcagatg gtgtccgcca tgggcgtcca tgaggcggca
    30481 cgcttcctcg gcgtccccga cacgcggccc gagcgccgag ccggccacca acgcttgccc
    30541 atcgccctgt tcctgaacga ccgaaagatc gaactcctgg cgaaccggat cagcgacacc
    30601 acctgcacaa ccgaccagcg ccatcgccgg atcagcctgg caacccggac gctgccccca
    30661 acgcaccggg ccactgtctg ggggcaggtc gctccgaggc ccgacaccac cccgcccctc
    30721 gacagcccac ggaagcacca gccgcccctg acggagtacg ccgaccagtt cgtcagcacc
    30781 atcgaccagc gcaaccgtac acgcgtgatg ccgccttcag cagcaccctc caccggggca
    30841 gggttcggcg ggaggccggg gctggcggcc tgacgcagcg cgactggcga ccgcggaggg
    30901 ttacgccgga aaaagtgccc ggggcgctat gcgacaaggc gccgagaaag cccgtgagtt
    30961 ctcgtctgac gcattttcaa gaagtcaagg caggggggat tggcttctgt tgtgcgggag
    31021 tcgcacagcg gcgtatggag gcgttctcgt cccgtcggtc aggagcgtct tcggtatctt
    31081 gggcggcgtc ccggtggccg acggccccga ggcccatgag ccttgggacc ctgttcgggc
    31141 tgccgtgccc tgtctccgcc agttgtccgg ccgctcccgc accgtggtgc gggagcgggg
    31201 tctgttatgc ccgaaagaga gcatctgtga ccacttacga cactcgcacc gccaccgata
    31261 cccccggatc ccagcagccc ggccacgtgg gggcggcgtc gtatgacgcc aacgcgatca
    31321 ctgttctgga cggcctggac gccgtacgca agcggcccgg gatgtacatc ggctcgacgg
    31381 gagagcgggg gctccatcac ctggtgcagg agctcgtgga caactccgtg gacgaggcac
    31441 tcgcgggggt ggctgaccgg atcgacgtga cgatcctggc cgacggcggg gtgcgggtgg
    31501 tcgacaatgg ccgcggcatc ccggtgggga cgcacccggt ggagaagcgg ccggccgtcg
    31561 aggtggtgct gaccgtgctg cacgcgggcg ggaagttcgg gggcggcggg tatgcggtct
    31621 ccggcggtct gcacggtgtg ggtctgtcgg tggtcaacgc cctgtcgacc cggctttcgg
    31681 cggagatctg gaccgacggc taccggtgga cgcaggacta cagggacggc gctcccaccg
    31741 ctccgctggc ccgccacgag gccacctcca ggacaggcac ctcgctgacg ttctgggcag
    31801 acggcgacat cttcgagacc accgaatact ccttcgagac gctggccagg cgtttccagg
    31861 agatggcctt cctcaaccgc gggctcaccc tgacgctcac ggacgaacgg ccctccgcgc
    31921 gcgcgacggc cgcggccgac gaggccgact cggacccggc agcgaagacg gtctcctacc
    31981 gctacgacgg cggcatcacc gacttcgtcg cctacctcaa ttcccgcaag ggcgaaccgg
    32041 cccatccctc ggtcatcact atcgccgcag aggacacgga acggctgctg tcggccgagg
    32101 tcgccctgca gtggaacggc cagtacaccg acagcgtgta ctcctacgcc aacgggatcc
    32161 acacccatga gggcggcacc catgaggagg gcttccgtac ggccctgacc accgtggtca
    32221 accgctacgc gcgggagaag aagctgctgc gggagaagga cgcgaacctc tccggcgagg
    32281 acgtccgcga gggcctgacc gcgatcatct cggtcaagct cggcgagccg cagttcgagg
    32341 gccagacgaa gaccaaactc ggcaacaccg aggcgcgcac cttcgttcag aagatcgtcc
    32401 acgagcatct gaccgactgg ttcgaccgca acccgaacga ggccgcggac atcgtgcgca
    32461 aggccatcca ggcggccacg gcccgggtcg cggcccgcaa ggcgcgcgac ctgacccgcc
    32521 gcaagggcct gctggaaacg gcggcgctac cgggcaagct gtccgactgt cagtcgaacg
    32581 acccggcgat gtcggagatc ttcgtcgttg aaggagactc cgccggcggc tcggccaagt
    32641 ccggccgcaa cccgcagtac caggcgatcc tcccgatccg cggcaagatc ctcaacgtgg
    32701 agaaggcccg gatcgacaaa attctgcaca accaggagat ccaggcgctc atctccgcgt
    32761 tcggcacggg cgtgcacgag gacttcgaca tcgccaagct ccgctaccac aagatcattt
    32821 tgatggcgga cgccgatgtc gacggccagc acatcaacac cctgctgctg accttcctgt
    32881 tccgcttcat gcggccactg gtcgaggagg gtcacgtcta cctctcccgc cccccgctgt
    32941 acaa
//
