BGC0000836 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000836 (Escherichia coli CFT073)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	arylpolyene	1	43,597	High	APE Ec	other:other

BGC0000836 - Region 1 - arylpolyene

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Location: 1 - 43,597 nt. (total: 43,597 nt) Show pHMM detection rules used

Region on contig edge.

arylpolyene: (APE_KS1 or APE_KS2)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

NRPS/PKS domains

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 43,598
Label		BGC0000836

Tailoring functions

Oxidoreductases: dehydrogenase

c1187: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Transferases: acyltransferase methyltransferase

c1201: acyltransferase

smcogs: SMCOG1141: acyltransferase

c1203: O-methyltransferase

smcogs: SMCOG1042: O-methyltransferase

Ligases: ligase synthase

c1186: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

c1189: Beta-ketoacyl synthase

smcogs: SMCOG1022: Beta-ketoacyl synthase

c1194: polyprenol-monophosphomannose synthase ppm1

smcogs: SMCOG1123: polyprenol-monophosphomannose synthase ppm1

c1197: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000836.5	1.00	other (other)	APE Ec	Escherichia coli CFT073
BGC0002008.3	0.80	other (other)	aryl polyenes	Xenorhabdus doucetiae
BGC0000837.4	0.62	other (other)	APE Vf	Aliivibrio fischeri ES114
BGC0002276.2	0.59	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0001197.5	0.48	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0002510.2	0.48	PKS	youssoufene A1, youssoufene B1, youssoufene B2, youssoufene B3, youssoufene B4	Streptomyces sp.
BGC0001987.2	0.47	PKS	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis
BGC0001723.5	0.45	PKS	oviedomycin	Streptomyces antibioticus
BGC0002047.2	0.45	PKS	brasiliquinone A, brasiliquinone B	Nocardia brasiliensis
BGC0000234.5	0.44	PKS	jadomycin	Streptomyces venezuelae ATCC 10712

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000836.5	1.00	other (other)	APE Ec	Escherichia coli CFT073
BGC0002008.3	0.80	other (other)	aryl polyenes	Xenorhabdus doucetiae
BGC0000837.4	0.62	other (other)	APE Vf	Aliivibrio fischeri ES114
BGC0002276.2	0.59	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0001197.5	0.48	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0002510.2	0.48	PKS	youssoufene A1, youssoufene B1, youssoufene B2, youssoufene B3, youssoufene B4	Streptomyces sp.
BGC0001987.2	0.47	PKS	koreenceine A, koreenceine B, koreenceine C, koreenceine D	Pseudomonas koreensis
BGC0001723.5	0.45	PKS	oviedomycin	Streptomyces antibioticus
BGC0002047.2	0.45	PKS	brasiliquinone A, brasiliquinone B	Nocardia brasiliensis
BGC0000234.5	0.44	PKS	jadomycin	Streptomyces venezuelae ATCC 10712

Similar known clusters from MIBiG 4.0

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS substrates

NRPS/PKS substrate predictions

c1197: X

AMP-binding (23..285): X

nrpys: (unknown)

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: -GFVLAIILK
Nearest Stachelhaus code(s):
Stachelhaus code match:: 0% (weak)

Link to PARAS substrate predictor