BGC0000845 - 1 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

BGC0000845 (Streptomyces clavuligerus)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 1	blactam	1	41,306	High	clavulanic acid	other:non-nrp beta-lactam

BGC0000845 - Region 1 - blactam

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Location: 1 - 41,306 nt. (total: 41,306 nt) Show pHMM detection rules used

Region on contig edge.

blactam: (BLS or CAS or tabtoxin)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

TTA codons

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Gene details

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Gene overview

MIBiG

Tailoring

MIBiG comparison

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

External annotation

Name		MIBiG
Version		4.0alpha

Type		Subregion
Location		1 - 41,307
Label		BGC0000845

Tailoring functions

Oxidoreductases: dehydrogenase oxidase oxygenase

SSCG_00150: pyruvate oxidase/decarboxylase

smcogs: SMCOG1055: pyruvate oxidase/decarboxylase

SSCG_00157: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

SSCG_00158: cytochrome P450

smcogs: SMCOG1007: cytochrome P450

SSCG_00168: cytochrome P450

smcogs: SMCOG1007: cytochrome P450

Hydrolases: hydrolase

SSCG_00151: asparagine synthase (glutamine-hydrolyzing)

smcogs: SMCOG1177: asparagine synthase (glutamine-hydrolyzing)

Lyases: lyase

SSCG_00165: argininosuccinate lyase/adenylosuccinate lyase

smcogs: SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000845.5	0.86	other (non-nrp beta-lactam)	clavulanic acid	Streptomyces clavuligerus ATCC 27064
BGC0000841.5	0.65	other (non-nrp beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate, clavulanic acid	Streptomyces clavuligerus ATCC 27064
BGC0001151.5	0.60	other (non-nrp beta-lactam)	valclavam, (-)-2-(2-hydroxyethyl)clavam	Streptomyces antibioticus
BGC0002276.2	0.57	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0002631.2	0.54	ribosomal	Myxarylin	Pyxidicoccus fallax
BGC0001948.3	0.49	other (other)	naseseazine C, C3-aryl pyrroloindolines	Streptomyces sp.
BGC0000844.5	0.47	other (other)	clavulanic acid	Streptomyces clavuligerus
BGC0000894.4	0.46	other (other)	citrinin	Monascus aurantiacus
BGC0000846.5	0.46	other (other)	tabtoxin	Pseudomonas syringae
BGC0000902.4	0.46	PKS	flaviolin	Saccharopolyspora erythraea NRRL 2338

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000845.5	1.00	other (non-nrp beta-lactam)	clavulanic acid	Streptomyces clavuligerus ATCC 27064
BGC0000844.5	1.00	other (other)	clavulanic acid	Streptomyces clavuligerus
BGC0000841.5	0.65	other (non-nrp beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate, clavulanic acid	Streptomyces clavuligerus ATCC 27064
BGC0001151.5	0.58	other (non-nrp beta-lactam)	valclavam, (-)-2-(2-hydroxyethyl)clavam	Streptomyces antibioticus
BGC0002276.2	0.57	NRPS	choline	Aspergillus nidulans FGSC A4
BGC0002631.2	0.54	ribosomal	Myxarylin	Pyxidicoccus fallax
BGC0001201.3	0.51	terpene	eremophilene	Sorangium cellulosum So ce56
BGC0001948.3	0.49	other (other)	naseseazine C, C3-aryl pyrroloindolines	Streptomyces sp.
BGC0000843.5	0.48	other (non-nrp beta-lactam)	alanylclavam, 2-hydroxymethylclavam, 2-formyloxymethylclavam, clavam-2-carboxylate	Streptomyces clavuligerus ATCC 27064
BGC0000894.4	0.46	other (other)	citrinin	Monascus aurantiacus

Similar known clusters from MIBiG 4.0