LOCUS       BGC0000846             22972 bp    DNA     linear   BCT 06-FEB-2006
DEFINITION  Pseudomonas syringae tabtoxin biosynthetic gene cluster, complete
            sequence.
ACCESSION   BGC0000846
VERSION     BGC0000846
KEYWORDS    .
SOURCE      Pseudomonas syringae
  ORGANISM  Pseudomonas syringae
            Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
            Pseudomonadaceae; Pseudomonas.
COMMENT     NCBI staff are still waiting for submitters to provide appropriate
            feature information.
            ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-10-17 14:18:49
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     source          1..22972
                     /db_xref="taxon:317"
                     /mol_type="genomic DNA"
                     /organism="Pseudomonas syringae"
                     /strain="BR2"
     misc_feature    1..22972
                     /note="tabtoxin biosynthetic gene cluster"
     subregion       1..22972
                     /aStool="externally annotated by: MIBiG"
                     /contig_edge="True"
                     /label="BGC0000846"
                     /subregion_number="1"
                     /tool="antismash"
     region          1..22972
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="blactam"
                     /region_number="1"
                     /rules="(BLS or CAS or tabtoxin)"
                     /subregion_numbers="1"
                     /tool="antismash"
     protocluster    1..20140
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[8274:10140]"
                     /cutoff="20000"
                     /detection_rule="(BLS or CAS or tabtoxin)"
                     /neighbourhood="10000"
                     /product="blactam"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      8275..10140
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(BLS or CAS or tabtoxin)"
                     /neighbourhood="10000"
                     /product="blactam"
                     /protocluster_number="1"
     cand_cluster    1..20140
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(BLS or CAS or tabtoxin)"
                     /kind="single"
                     /product="blactam"
                     /protoclusters="1"
                     /tool="antismash"
     CDS             193..636
                     /locus_tag="ctg1_orf1"
                     /transl_table=1
                     /translation="MQLNRVYELRSLIPRVPHCAFNQEPFKIVNNPAVLFCQCFGFLRC
                     SFGIKPCPPIICCQYHRAAIINVHHSRIACRRNDDEPFAIMRLKPSVHQGQRSEEHGLF
                     TLKADVVGLLFLGVIRVLHPFKPTFRWGNCPSARPELFEELSRH"
     CDS             717..1883
                     /locus_tag="ctg1_orf2"
                     /transl_table=1
                     /translation="MHL"
     CDS             1954..3147
                     /locus_tag="ctg1_orf3"
                     /transl_table=1
                     /translation="MSLRSLKAG"
     CDS             3144..3974
                     /locus_tag="ctg1_orf4"
                     /transl_table=1
                     /translation="MSAERSDQIVERSFRTRALIDVFHDHRTGQRHARQFRVGTIAGNH
                     HRVGRHLAEAHFATRAVDDRRRSTEVDPHANHRSATHDDAFGDLAAGTDENVVFNDYGV
                     VADGLEYAAQAHATGDMAA"
     CDS             3975..5237
                     /locus_tag="ctg1_orf5"
                     /transl_table=1
                     /translation="MFNAPGGVEDVNGLPLNRAGMIIKGLGPTDFNDIAIVCQHQFCRT
                     QPAIVGKPHGMTMGTCIMDQCEVAD"
     CDS             5272..5967
                     /locus_tag="ctg1_orf6"
                     /transl_table=1
                     /translation="MGH"
     CDS             5984..7129
                     /locus_tag="ctg1_orf7"
                     /transl_table=1
                     /translation="MEAGLRASCVAVRWYTYRFLHVFDGLRGRVA"
     CDS             8275..10140
                     /gene_functions="biosynthetic (rule-based-clusters)
                     blactam: tabtoxin"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177:asparagine synthase (glutamine-hydrolyzing)
                     (Score: 432.8; E-value: 3.6e-131)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_orf8"
                     /sec_met_domain="tabtoxin (E-value: 0.0, bitscore: 1502.8,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="GATase_7 (E-value: 3.9e-30, bitscore:
                     94.9, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 3.8e-70, bitscore:
                     227.8, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MSGMAGWVNLRHGVGQQANLPHSKVTKVILDMIAAMAGRGPDGQA
                     VWLGPDLALGHCSTVASRYDFNEQPWIGEIRGATVAIMYTGQIYNMWQLQQELASFGPA
                     PDRWSYAEIIRRAYGRWGTGFVQHLEGMFAIALWDGQKRELLLARDRLGLQPLYYTLTD
                     GGIIFASVPTAIQAHPQFTAKLDRSALAIVLQPRMAMPGETPLKGLHELPPANVLSFSK
                     RGHTQVRYWQLESAPHTDNFEQTSDHVRALLEGVVARQFEDQVPSAAMLSGGIDSTSVA
                     ALVMKQLATRGAGPALDTFCLKFDTDEDAFTSSELRPDIDAPFAALAAEYMGTRHTTLS
                     ATMQDLLNVIPATRTARGLPGWGQFDASMYLLFERMRDNFSVALTGEAADEIFGGYPYY
                     FKPDLLARAQFPWLGDGPKLADYLSPALITAQQVAEDERARYDYWLSQVPRLPGESGEA
                     ARMREVLFLGMSGPLSVILDRKERMSMSQGLEVRVPFCDPELIQYVWNVPWEMKSRGGV
                     KGLLKSAMRDILPPTTLSRKKSAYPHIQDTEYDRVLISEARWIATDPKSPIGWMFDTPR
                     LSALIDQIAANQLNASMLPGGASPAHLLIQLVEMHRWIVDNRVAV"
     CDS             10189..11052
                     /NRPS_PKS="Domain: TauD (5-272). E-value: 1.1e-63. Score:
                     207.3. Matches aSDomain: nrpspksdomains_ctg1_orf9_TauD.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121:dioxygenase, TauD/TfdA (Score: 271.1; E-value:
                     1.6e-82)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_orf9"
                     /sec_met_domain="TauD (E-value: 4.5e-64, bitscore: 207.3,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=1
                     /translation="MLELVPITNLIGTEVRGIDVNSKLSDDVIEALYEAWISSTILLFR
                     GQSMTPDQQLKFSRNFGELVSYTRSQFSEKTQPEILILSNITKDGKLIGSPVSGRVWHT
                     DGHYLEVPPAGSMLHALEIPPEGGDTWFANMFAAYEALPESVKQRIEDLKVIISRTQSR
                     PYNYPDRPAPSAQELAEWVDVAQPLVRRHEVSGRKALYAGGNVPWRIEGLPLEESAPLI
                     TFLQEFSVQPQFIYRHRWVPGDIILWDNRSAMHKATVYDDKYRRLLHRTTIGARATESR
                     YRKRQA"
     aSDomain        10204..11004
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_orf9_TauD.1"
                     /evalue="1.10E-63"
                     /label="ctg1_orf9_TauD.1"
                     /locus_tag="ctg1_orf9"
                     /protein_end="272"
                     /protein_start="5"
                     /score="207.3"
                     /tool="antismash"
                     /translation="PITNLIGTEVRGIDVNSKLSDDVIEALYEAWISSTILLFRGQSMT
                     PDQQLKFSRNFGELVSYTRSQFSEKTQPEILILSNITKDGKLIGSPVSGRVWHTDGHYL
                     EVPPAGSMLHALEIPPEGGDTWFANMFAAYEALPESVKQRIEDLKVIISRTQSRPYNYP
                     DRPAPSAQELAEWVDVAQPLVRRHEVSGRKALYAGGNVPWRIEGLPLEESAPLITFLQE
                     FSVQPQFIYRHRWVPGDIILWDNRSAMHKATVYDDKYRRLLHRTT"
     CDS             11049..13133
                     /locus_tag="ctg1_orf10"
                     /transl_table=1
                     /translation="MSDYDYIIVGAGAAGCVLASRLSENPDIQVLLLEAGAERRSPLLS
                     IPVGEVLLMGNPKYDWCFETRPDPTLGGRRLQIPRGRLLGGSNLINGMIFVRGQRADYD
                     EWASQGNAGWAWDEVLPYFKRLETSVDVHGEARGQDGPIHVALPRERDELCDAFLAAAG
                     EAGHLHNPDYNSGEQEGFGYYQVNHDKGRRSSAYGRYLLPARKRANLTVVTEAPVQKLR
                     FEGEHCIGVDYLSGTLQFARARREVILSAGVIQSPQLLELSGIGAPAVLEKAGVAVQHV
                     LPGVGENFRDHFASRLKWRIRQKITFNERTRGFALFKEVLHYLARRRGVLSLPIALGHG
                     FVKSREQEPRPDLQFHFAPASYGPGSSRRLDTLPGMTVGLYPLRPESTGSIHIRSSDPA
                     VAPVIESRFLEHEDDQRRMIAGMRILREIAAQPALRAYCDHELSPGTEVESDEELLEFA
                     RTQGDTSYHPVGTCRMGKDELAVVDHRLRVHGLQGLRVIDASIMPTMVSGNTNAASLMI
                     AEKGADMVLQDYASSSMSRQELFSIVEGDPEEQQVAALLQRSEDYARSLYPAESVHMLD
                     VAQLKAPGVSFVVAREFNSGEVLGCGAVVNIGNGEAELKRMFVADNARRRGVGVRLLKR
                     LEHLARRNGARTLLLETGVSQPEAISLYRGAGFRDRGPFADYQEDPLSVFMEKTIDEQA
                     "
     CDS             13120..14082
                     /locus_tag="ctg1_orf11"
                     /transl_table=1
                     /translation="MNKPEASLIGPVTPVSRWVGRAGILYVAAFLVLANANAVFSGNLL
                     QQLHPFTFLFWNFVITSGFFLTRLLLSSGTSGLAIEGRAAGPLTVLNFTSALNWIGYFY
                     ALRYIEPAIVSAIMGGLGPVSTILLERVVRRRQLPLYTYAVAAGILSGTALLAWASLVG
                     LAGIRPINFSDTLIGLAAAAAGGASQALNTIATKQLGERSWTATRIMAHRFYLLIIVAA
                     ALTYSGPGFAIASSTQVGGLAIATLLGVIIPLWLLQRGILLSEPFTVAALLAWAPLLTY
                     VFQVFDARIQWSMTSALGCSVIALVTVFGTWMKFKGDRK"
     CDS             14079..15338
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 74.3; E-value: 1.7e-22)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_orf12"
                     /transl_table=1
                     /translation="MTQAKENILVVVDGYSSGSQLPTLMAESGWKCVHVSSSANPPEYY
                     LRTYHKDEYIAHFEYQGDIQSLASAVEAWHPAAVLPGTESGVIVADLLAAALQLPGNDP
                     STSLARRDKYTMHESLKAVGLRSMDHFLAVDRDALSAWAERGSWPVVIKPQASAGTDSV
                     TFCADQGELLESFDQLFGTVNQLGERNNAVLAQRLLVGPEYFINGVSGHGKHLITEIWR
                     ADKLPAPDGGWIYDRAVLFDPTSPEMQEIVRYVHGVLDALGIRYGANHTELIVTADGPT
                     LIECASRLSGGLHRPAANYAVGASQLDLVGKLVREGESAIDDILQTWQPHRYALWQVQF
                     ISNQEGVVARSSYDELLKTLKSNAWLQRAPKEGDTVVKTVDLFSSPGIVFMSHADGNVL
                     HDDYRTVREWERTSRLFSVQ"
     CDS             15444..16745
                     /gene_functions="transport (smcogs) SMCOG1074:major
                     facilitator family transporter (Score: 372.6; E-value:
                     4.3e-113)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_orf13"
                     /transl_table=1
                     /translation="MKPMDSQRQQRRMLLAVGIGTTLEWFDFTLFAIFSLHIAKIVFPA
                     QDQLMSLLATFVTLAVGFVARPLGAFLIGRYADRHGRKKALILTMNMMAAGTVMIALCP
                     GYSMLGYGATVLLVVARIVQGLAAGGEIGSALAYLCESAPVSRRGFFTSFQQVAQAGSF
                     LLCGLFASILATVLTPEQLGSWGWRIPFVLGVFIYLVGVYVRRTINESHEFQAHAREGV
                     EVPAREILRHWRSLVLGIGFVALWTVCTQLINFMPAYAQAMFNLDAGKAYYGITLVGFI
                     TLLSPLGGWLSDRWGRYNVMLLGALGVLMLAYPAFLALKHNPQDMGLMLLQAGLAVFMV
                     LYAGPASAALAELFPVAVRSTGISVAYASSVLLFGSFTPMLVTLLYRYTGDPMMAAYYL
                     LAAALVSFFALVIARQSQVSFVGRLISKGKQVEY"
     CDS             16805..17215
                     /locus_tag="ctg1_orf14"
                     /transl_table=1
                     /translation="MTTNAKRDDSAAMRIGQSLGRGVAGVLRLEKALWSSSIIAGLPRP
                     IISPIKWAVRVAVIGGGVFFAAWGLLYVLAVVCFLAIAIGFVTNPGIERGLRGSQLVHF
                     DQASEDASGMGESGWMSGPQGYGYYENGLKQQ"
     CDS             17272..18804
                     /locus_tag="ctg1_orf15"
                     /transl_table=1
                     /translation="MFLHQRHDYICTAASRRFGVPCTFSQALHKATNSRTSPSQRKYPE
                     TWEHDEHCAHHKVQQ"
     CDS             18801..19175
                     /locus_tag="ctg1_orf16"
                     /transl_table=1
                     /translation="MWQVNSRYSGSAPKLEKENDEDGHDLATTKSRGE"
     CDS             19178..20398
                     /locus_tag="ctg1_orf17"
                     /transl_table=1
                     /translation="MVTFRRVLQLLEAVRRWIALKDALGAVLPALSSL"
     CDS             20367..20546
                     /locus_tag="ctg1_orf18"
                     /transl_table=1
                     /translation="MSIFPAVPIVTALPPPTL"
     CDS             20567..21505
                     /locus_tag="ctg1_orf19"
                     /transl_table=1
                     /translation="MLKVRTAKKGLSFPLAAGIRPP"
     CDS             21502..21975
                     /locus_tag="ctg1_orf20"
                     /transl_table=1
                     /translation="MSRRISLARCVLIFGGGAPLDNAIFSRRSVRFPVHHKLAVDHHSR
                     HLRYPHAPGVY"
     CDS             22377..22565
                     /locus_tag="ctg1_orf21"
                     /transl_table=1
                     /translation="MKLEVSQLIAVLASIGLGEAGQRTADPFYSEAFIIALLLGFFLMM
                     AALAREVFEVLREKSLI"
     CDS             22697..22933
                     /locus_tag="ctg1_orf22"
                     /transl_table=1
                     /translation="MATHKELVAELINVLNSDGSSEVRAGAAKGLGAAGGADALRALRA
                     ALKHDSKILVRATSAEAVGLILGRGNLQDMMDQ"
ORIGIN
        1 ccttttcgtc atccatttcc ggcggactcg tcggcctttt cgggtaaggc acttaccctt
       61 attcccccat tccattcaaa cccttcgctt tgccatttgc ttcagctcat ntcgcccctt
      121 tcggggcgga agacctgagg cagacggagt tggacagcaa ttggtcgggt cgaaggcaaa
      181 ggcatggggc agtcacagct caacagggta tatgagctcc ggtccttgat tccgcgcgtt
      241 ccccactgcg cgttcaacca ggaaccattc aaaatcgtca acaatcctgc agtgctcttt
      301 tgccaatgct tcggctttct gcggtgtagc ttcggaatca agccatgccc gcccatcatc
      361 tgctgtcagt accaccgggc ggcgatcatc aatgtccacc attccagaat cgcttgccga
      421 cgtaatgatg acgaaccctt cgccatcatg cggctcaagc cctctgtgca ccagggccaa
      481 cgcagcgaag aacatggact tttcactctt aaggcggatg tagtagggct gctttttctt
      541 ggggtcatcc gggtccttca cccattcaaa ccaacctttc gctggggcaa ctgcccgtcc
      601 gctaggccag agctctttga agaactttcc cgtcatcacg gtttcgactc gagcgttgac
      661 tgggcccggt cgtttgcctt tcgcccagag aggttcccgt aaataggggc aattgctcac
      721 acctgtagac gatgccggac gagggcaacc caataggcca cgcccatggg cataatttcg
      781 tcgttaaagt cataattcgg attgtgcaac gaacaaccag gctcggctga accgttgccg
      841 atccagatat aggcgccggg cttgcgttcg agcatgaagg caaagtcttc cccggtcatg
      901 cttggtgcca cggtggtacc gacgttttcc cgcccggcca cggcgctggc ggcgaccacg
      961 caatgctctg catgcaaggt gttgttgatc actggcggcg atccaaattc gaaaaactcc
     1021 agcgatgcac gcacgcccat tccggcagct agttgttcaa cgagcttgat cattcgacgc
     1081 gacgcaattt cgccagctgc ggggcgaaag taacgcagag tgccggtaag gcgggccgtg
     1141 tcgggaatga tgttgtgggt atgcccagcg tggaactggg taacgctgag gaccagtgca
     1201 tcggccgggt cgatgttgcg cgaaacgatg ctttgcaatg ccgtgaccag gtgtgccgcc
     1261 gccaataacg gatcagcgcc ctgatgggga atcgctgcat ggcagccgca gccgctgacc
     1321 acaatttcaa agggccttgc gccagccatt gccgcaccgt gatgcaccac aaatcggccc
     1381 gcctccagac ctggccaatt atgcaggccg tacacgcatt cggcgcgaaa tttgtcgaac
     1441 aggcctgcgt tcatcatcgc cttggcccct gtaccgatct cctcggccgg ttgaaagatc
     1501 aagtggactt tgccagcgaa gcggcggtct gccgccaagc tgctggcggc gcccaagagc
     1561 atcgttatat ggccatcatg accacaggca tgcatccagc cgtcgtggcg tgagcggtgg
     1621 gcgaaggtat tttcttcctg gatgggcagt gcatccatgt cggcgcgcag agcgatctcg
     1681 atgccgggct gctcgccttc gatagtcgcg acaacaccgg tcccgccaat gcccaagtga
     1741 ggctgcaggc cgaaacttcg tagtgtctcg gcgatgaaag cgctggtctt gctctcggcg
     1801 aatcccgcct ctggatgctg atgcaaccag cgacgccagc cgaccatacg ttcttgcagc
     1861 gctgaatccg ttgccattgc catcttgctg tccctgtccc ggaagtgact ctgaatcggt
     1921 atcgcatccg ccgagggatg ctggtatgca agctcaagtc tgcgcagcct caaggccggt
     1981 tagctcagcc ctgaggcgca gcagtgcctc actcatgatc gattgttgat gaactagagc
     2041 gagacgcacg aagccatttc cggggttgct gccgttgctt tcggcatgac acaaatagcg
     2101 tccgggcatc acgcgcaaac cctgcttggt ccataaccta cgcgctgcat cctcgccatc
     2161 ggcgacgggc agccagagga aaaaaccggc ttcggcgcgc tgatagccag gcacttgggc
     2221 gaggcaatta tcggccatgt cccagttgcg tttcagcgcc tgcgtttgct tctgcacatg
     2281 tgcgtcgtcc tgccacagag cggccgaggc cgcgcacgtc ggccaggcga gcgacacccc
     2341 gcaggagcga ttgaaattgg cgtagtcagc aacactctgt gggtcgccgg caatgaaacc
     2401 gctgcgcaaa cctggcgcgg cagagcgctt cgacaggctg tgtagcacca cgaacgggca
     2461 gggcgcgact gtacctgcct cgactagact gagatagcct ggcggcgctg aatgccagac
     2521 cagatccgtg tagcactcat cgaccagcaa gctggcctga gccaggtgtg cctggcggct
     2581 gattgccgcc agcgtatcgg ctgcgagaat tttgcccagc ggattgccgg gattgcacag
     2641 cactagtgcc gcgacgctgt cgccggctaa tgccagttgg acggcaagat tcgcctccag
     2701 ttgcccattg ctcagatcgt agaacaaggc ccgcgcgcct gctgcatcgg ttgcggctac
     2761 atacgtggga tagaacgggt tgggcaacac aaccaccggc gtcgcgacgc cccgtgcccg
     2821 agcccgggtg accgcgaggg cgatgcacgt ggcgaccgcc tgcttggtcc ccggggtggg
     2881 ttcgatggca atcgagttgc cgaggctggc ggcgatgcca aagcgtcgct gcagccagtg
     2941 actgtaggcc tcgcgtagtt gcgtcgtcgc ggtcagcggc ggatagcggg tccagtcaca
     3001 gagttcagac aacggttcca gcagcgatat tgggtcgccc agtcgacttt cgcccaagtg
     3061 cagggcgatg accggcaagc ctggcgcggg cggtaggtca tcaagcaggc cctgcagcct
     3121 gacgaaagca ttgcctgcgg agttcatcgg ctgagcgctc ggaccagatc gttgagcgca
     3181 gttttcgaac gcgtgcgctc atcgacgtat ttcacgatca ccgcacaggc cagcgacacg
     3241 cccggcagtt tcgggtcggc acgattgccg gcaatcacca ccgcgttggc cggcacctcg
     3301 ccgaagcgca cttcgccact cgcgcggtcg atgatcggcg tcgaagcacc gaggtagacc
     3361 cccatgccaa tcaccgctcc gctacgcacg atgacgcctt cggcgacctc gctgcgggca
     3421 ccgatgaaaa cgttgtcttc aatgactacg gggttgtcgc cgatgggctc gagtacgccg
     3481 cccaagccca cgccaccgga gatatggcag cgtgagccga cttgggcaca ggagccgacc
     3541 gtcgaccagg tatcgatcat tgtgccttcg ccgacgtacg cgccaatgtt aatgaagcac
     3601 ggcatcagta cggcgcccgg ggcgatgtac gcaccggccc ggacgacggc gccggggacc
     3661 acgcggatgc aagcgtcacg aaacgcggcg tcgtcccatt gttcgaattt taggggtagt
     3721 ttgtcgtagc ttttcggccg cccggggttg gtttcgccca cggtattttc gcgagttaga
     3781 aaggacagca gaatcagctt cttgacgaag gtatcgcaga cccactgtcc ttcctgcgca
     3841 cgtgctgcgc ggagctcgcc acgctccaga gctgcgaggc cggtttcgat cggcggcacc
     3901 agagccgaca gttcttccgt cgtcagctgc gtacgccgct cgaacgcttc ttcaatcaat
     3961 gcacggttac tcatttattt aacgcacctg gtggggttga agacgtcaac gggttgccat
     4021 tgaatcgggc cggtatgatc atcaaaggtc tcggcccgac ggatttcaac gacatcgcca
     4081 tcgtctgtca gcatcagttc tgccggacgc aaccggccat tgtaggtaaa ccccatggca
     4141 tgaccatggg cacctgtatc atggatcaat gcgaggtcgc cgattagcgg gctcggcagc
     4201 aggcgatcca cggcaaactt gtcaaagttc tcgcacagtg cgccgactac atcgaacaca
     4261 ccttcggggc gttgatcggc gaagggcagc gtcaggtggt ggtaggcgcc atacagtccc
     4321 gggcgcatga gcgccgacat cgatgcatcg aggccgacga tttcccgccc tttgctgcag
     4381 cggttgatga cccgagacac aagcaccccg tgcgggccgc tgatgtaacg gcctaactcc
     4441 atcagcagct tgggtgtgtt gtgtgggaat gcttgtttca acgcgcgttt cagcgcatcg
     4501 gcatacgctg tgagatcaag agcctggtcg tcgatccggt agggaatgcc taggccaccg
     4561 ccgatattta tgtattcgag ttcgatgcct gcctcgcggg ccactcgcgc cccgacctcg
     4621 atgacttgca cgccggcctg cacggcggcc tccagtgaca gctcgttggc gcacatcatg
     4681 ccgtggatac caaaacgtcg ggcaccgcga tcccatgcct cgcgatagct ctgaactagt
     4741 tcggcctcgg gaatgccgaa ttttgattgc tgggcattgc ccatctgtga cgaccgggca
     4801 atgacgccat ggggcgacac gcgaaaggca acgatatccg gcaaggctat cacttgttca
     4861 agcatgcttc ggtcgtcgaa cgtaactagg gcgcctgcct gcagcgccat ctggtattcg
     4921 ctgagagacg tgttgttgga ggtgaaaaca atgtcgtcac cccgcgcgcc cagtcgttcg
     4981 gcaagcatca gttcgaccgg cgacgagcag tcgagcccgc tgccctcctt gagcagcagg
     5041 gacaggatgg ccggagtggg tagcgccttg accgcgaagt actgacgaaa cgcgctgtcg
     5101 gcgaaggctt gcgccacgtt tcgatgagtc tggacgatgg cgcgctcgtc ataaatatga
     5161 aagggcgtcg ggtatgtatt cgtcagctca tcaagtaggg ggaacaaacg tcgggcgaag
     5221 ctttcggata ttggcacggc ggtttctcct cgcggcgcag gcgtgattga ctcagggcac
     5281 tagtgcgacg caaagggttc gattacgcag accactgatc gggcgtgtgt aagggaagta
     5341 gtacgactct tcgatcttga agccagcctc agtcagcgca tcacgcaggt agtctctgga
     5401 tatgaaccag aagccgtcga ctttatcgtg ggcggcaaag agagcctctg gatcgcgagg
     5461 cgagtcgttg gagaaaacta gggttgtgcc ggattctaga ttcagctcct tgagtttttc
     5521 gaaagttggc ttgagctcta actctgggtg gaacaagtgg ccgagcaaac cgtctgcgta
     5581 gatcgacttg acgccagcga gagcgccggg ctcgagttcg aagaagtcgg ctgtgtacgc
     5641 atccactcct tttttccggc tcagcgcaac tgcttcatcg ttgaagtcga tagccagcac
     5701 gcgacgtttg gcttgcacca gatcgccctc gacaaaacca ttaccgcagc caatggagaa
     5761 aattatcgcg ccttcctctg tgagggactt gagcttgagc cccagatgcg agcgatattc
     5821 ttggctgtag gtggatggcg tgatggagtc gttgaacgct ccaccctgtt cccagatctc
     5881 gtatatcgtg gcatcgctat cgccaaaccg gcgggtggtg ccgtagtagt cttcgacctg
     5941 tttgaggtcc tgtatcgaat tgttcatctc tgtctctcct tgtttagagg cgggcttgcg
     6001 cgcaagttgc gtcgcagtcc gttggtacac gtacaggttc ttgcacgtat tcgatggact
     6061 gcgcgggcga gttgcctagc gcagtgacca gtggctgcaa cggctgcagc cgtgctggtc
     6121 cgtaaaactg gtagaaggcg acagcagcct caggattgcc cgcgagcagg gcgtcggcta
     6181 aaactcgtgc tagcgagcgc aagccagcga gcaaggcgcc atgatcgacc agcagtttta
     6241 cgggttgatc acctccatgc tgcagagtca gagctcctag ctggacgaaa taagacaatt
     6301 gcaagtacat cccgtcgcaa tcggggaaaa gcccgagccc ccggtttacg taacgcaagc
     6361 actcacccag gtagtattcg agtacctgct cgagcgggat ttgcagcgcg ggcgcccaga
     6421 cttgggcaag gaccaggatg ccgaaaacat ccgccgcgac ttcttgcaac accaccgagg
     6481 tccagcgatt ggcgcggttc aaaggcgagt aggtggtttc ttggcgatag ataaaatggc
     6541 cgagttcatg gctgagcact ccaagtgtcg ggatgcggcg cagaggctcg ctcgtcacgt
     6601 tatagtcggt tcctgtcgac aggaactgcc gtgccagcgg cgcagctagg cactcgacca
     6661 tcgctgcatg ggtgttggca aagtaataag tcttcttgaa cggcgagtgt tttacgcctt
     6721 catcttccgg gaggaagtac gcgatatgtt tgggatgaag gttgccttcg ccggccatga
     6781 aaaacagatc tgtggcggcg aaagcgggca catcgcccaa ccgcaagtgg gtatgcagac
     6841 tcttaaggta agcgggcact tgatccacca gcgccatagc ctgctccacg tcccgttgcc
     6901 gagccttatt gagctggcaa ccgaaggcgc ttggcaatcc tcccgtctgc ttgccatacc
     6961 aggttgcgag ctggccggcg accagtgtga cctcttcttg caggcctgct agagtcttga
     7021 gtatttcgtt gtcgtagccg tcgtcaatag ccttggccct aagtagtagt gcctggcgat
     7081 catgcggccg ctctagatcg tcacctagat cacgcagtgc atgtgccacg gcgcctggat
     7141 cgctgaagcg ggtccgctct gatacgccgt gaagcttggc atcgcgccat tgctcttcaa
     7201 tcgcggtcct gagagcgtcc aagcgttctt gccatgcccc gcctaggcta gggttggctg
     7261 gtgttaggtc gagcgaagtt atgctgtaac tgtcacacgg gggccagacg tgttgcgata
     7321 accacggtaa gtggtggctc tggcaaggtt gcccgaataa tcgaaccgat tcacgctcat
     7381 aattccctct acgctacgtg ttgaagtctg gagacgcaca cttcgccatc cggcaggctc
     7441 gggggtacgc gtctacttta atgccgacgc acatgctccc ttaatgctgg caacgataca
     7501 gatgatcgat atacgcagat taagtaggca tgacgttgct tattagctga aggcagtcac
     7561 gcttgcacta gctcctgacg aaaaacaatc agggcagcac aaaatcgatg accgctaaat
     7621 gatgtgcaga taactatcca tatacattcc cttactcata ttccatatga aggtgtggca
     7681 cgctgggcgc cacgctgctt gtcaaaaagc ataacagcga ttttttttct acgacaagta
     7741 ggaaaacaaa aaaaaatgca gaaagtcgcg tgtgctttga acgatttttg agaaaagtct
     7801 ttaaatatta atggcttgtg cggcttataa tattttattt gggttctcag atctggcagt
     7861 ctaagccttg ctacgtaccc gtctgtctac taattcgtga attagtgttg tatgtcatac
     7921 gacattctat atgtcaaaaa gacatcgttt tttggtatgt caaaaagata tcaggctacg
     7981 tcatgaggtc cattttggtg cgcgacaaag tctcacgcac tatattagtg cgtgtcggga
     8041 ggggggttgt ttttataact ttaaataatg aatcgctttg atttaggtgt cttagacttt
     8101 caacgagacg cttgtcatga gtgtatggct tgatgtagct tatactcggc tgaagagata
     8161 gattaaaaat aagaaactat ctgtttcggc ccttaggcct cgagcattgg tatacatgga
     8221 aacggtcgcg ccaataaagg cgttgcccgg tagataattc gaaaggaggg tcatatgagt
     8281 ggcatggccg gttgggtaaa cctgcgtcac ggtgttgggc aacaagcgaa tctgcctcat
     8341 tcgaaggtga ccaaggttat cttggatatg atcgctgcca tggctgggcg tggtcccgac
     8401 gggcaagcgg tttggctcgg cccagatctt gcgctgggac actgcagcac agttgcttca
     8461 cgctacgact tcaatgaaca accttggatc ggcgagattc gcggcgctac ggttgccata
     8521 atgtataccg gtcagatata caacatgtgg caattgcagc aggaactcgc tagctttggg
     8581 ccagcaccgg accgctggtc ttatgccgag atcattcgac gcgcctatgg gcgctgggga
     8641 acaggcttcg ttcagcacct tgagggcatg ttcgctattg ccctttggga tggacagaaa
     8701 cgcgagttgc tgctggcccg tgatcgcctt ggcctgcaac cgctttatta cactttgacc
     8761 gacggcggaa tcatcttcgc cagtgtgccc acggctattc aggcccatcc tcaatttacc
     8821 gccaagctcg acaggagtgc gttggcgatc gtgctgcagc cgcgtatggc aatgcccggc
     8881 gaaactccat tgaagggctt gcacgaactt ccaccggcta acgttttgag cttcagtaag
     8941 cgcggccaca cgcaggtgcg ctactggcag ctggagagtg cgccgcatac cgataacttt
     9001 gagcagacct cagaccatgt gcgcgcgttg cttgaaggag ttgtggcgcg ccagtttgag
     9061 gatcaagtgc catccgcggc tatgctatct ggaggcatcg attccacgtc ggttgccgct
     9121 ttggtgatga aacaactggc gactcgaggc gcgggtccag cactggatac gttttgcctg
     9181 aaattcgaca ccgatgaaga cgccttcacc tcaagtgaac tgcggccgga catcgatgca
     9241 ccgttcgctg cactggcggc tgagtacatg ggcacccgtc ataccacgct aagcgctacc
     9301 atgcaggatt tgctcaatgt gattccggcc acgcgtactg cccgcggctt acccggctgg
     9361 ggccagtttg acgcgtctat gtatctgcta ttcgagcgca tgcgagacaa tttttcggtg
     9421 gcattgaccg gtgaggccgc cgacgagatc ttcggtggct acccctacta cttcaagcct
     9481 gatttattgg cccgtgcaca attcccatgg ttgggtgatg gtccgaagct ggccgactat
     9541 ctatcgccgg ccctgataac tgcacaacag gtggcagagg acgagcgtgc ccgctatgac
     9601 tactggctta gtcaagtgcc gcgtctgcca ggagagagtg gtgaggcggc tcgcatgcgc
     9661 gaggttctat tccttggcat gtctgggcct ctatcggtga tccttgatcg taaggagcgc
     9721 atgagcatgt cccaaggctt ggaagtgcgg gtgccattct gtgatccaga attgatccag
     9781 tatgtgtgga acgtaccgtg ggaaatgaaa tcccggggtg gggtgaaagg tcttctaaaa
     9841 tctgcaatgc gcgacatcct gccgccgacc acgttgtcac gcaaaaaaag cgcctacccg
     9901 cacattcagg ataccgaata cgaccgagtg ctaatcagcg aagcacgctg gatcgcgact
     9961 gacccgaaat ctccgattgg ctggatgttt gacaccccgc gcctaagtgc actgattgat
    10021 cagattgcgg ccaatcagct aaacgcgtcg atgctgccgg gcggtgccag cccggcgcat
    10081 ctgttgatcc agttggtgga gatgcaccgc tggatagtgg ataaccgggt cgcggtgtaa
    10141 ggcacggtca gcacggaaat ctggccttag ataaatcaag gaggcggtat gcttgagctc
    10201 gttcccatta ccaatttgat cggcacggaa gtccgtggca ttgatgtgaa ttccaaactc
    10261 agtgatgacg tcatagaagc gctttacgaa gcctggatta gcagcaccat cctgttgttt
    10321 cgcgggcagt ccatgactcc tgatcaacag ttgaaattca gtcgtaattt cggcgagctt
    10381 gtgagctata cacgctcgca gttcagcgaa aagactcagc cggaaatcct cattttgtcg
    10441 aacattacga aggacgggaa gctgatcggc tcccccgtta gtggtcgtgt ttggcatacc
    10501 gacggacact atttggaggt gccgccagca gggtcgatgc tacacgcgct ggaaattccg
    10561 ccggagggtg gcgatacttg gttcgccaac atgtttgccg catatgaggc gctgcccgag
    10621 tcggttaagc agcgcatcga agacctcaag gtaatcatca gtcggaccca gtcgcggccc
    10681 tacaactatc ccgaccgacc ggcgccatct gcgcaggaac tggccgaatg ggtcgacgtg
    10741 gcgcaaccgt tggtgcgtcg ccatgaggtc agtgggcgca aggcgcttta tgctggcggt
    10801 aatgtgccat ggcgtattga aggattgccg cttgaggaaa gtgcgccact tatcacattc
    10861 ctccaagagt tttcggtgca gccgcaattt atctaccgac accgctgggt gccaggcgac
    10921 atcatcctct gggacaaccg cagcgccatg cacaaagcta cggtgtacga cgataaatat
    10981 cgtcgtctgt tgcatcgcac caccattggt gcccgtgcca ccgagtctcg gtacaggaag
    11041 cgccaggcat gagcgattat gactacatca ttgtcggcgc aggtgccgct ggctgtgtac
    11101 tagcgtcacg cttgagtgag aatccggata tccaggtgtt gctgctcgaa gccggtgctg
    11161 aacgtcgcag tcctttatta tctatacccg taggcgaagt cctgttgatg ggcaatccga
    11221 agtacgactg gtgcttcgaa acccggccgg atccgacgtt gggcgggcgc cgtctgcaga
    11281 ttccgcgggg gcgcctgctg ggcggctcaa accttattaa cggtatgatt ttcgtccgtg
    11341 gccagcgtgc ggattatgac gagtgggcaa gccaagggaa tgcgggctgg gcttgggatg
    11401 aggtactgcc gtatttcaag cgcttggaaa ccagtgtcga tgtgcacggc gaggcccgtg
    11461 gccaggacgg accgatccat gtggcgctgc cccgtgagcg tgacgaactg tgcgacgcct
    11521 ttcttgctgc cgccggcgaa gccgggcacc tgcacaatcc cgattacaac agcggcgagc
    11581 aggaaggttt cggctattat caagtaaacc atgataaggg gcggcgctca tcggcttatg
    11641 gtcgatacct gctgcccgcg cgcaagcgcg caaaccttac ggttgtaacc gaggcgccag
    11701 tacagaaact gcgctttgaa ggcgaacact gcataggcgt ggattatctt tctggcacat
    11761 tgcagttcgc tagggctagg cgtgaagtta tcctaagtgc gggggtgatc cagtcgccgc
    11821 aactcctgga actttcggga attggtgcac ctgcggtgct ggaaaaggcg ggtgtggcgg
    11881 tgcagcatgt actgcccggc gtcggtgaga actttcgcga tcacttcgcc tctcgtttga
    11941 agtggcgcat tcgccagaag atcaccttca acgaacgcac gcgtggcttc gccttgttca
    12001 aggaagtcct gcactaccta gcgcgtcgtc gtggcgtgct gagcctgcca attgctctgg
    12061 ggcatggctt cgttaaatcc cgcgagcaag agccgcggcc cgatttgcag ttccatttcg
    12121 ccccggccag ttatggtccc ggttccagtc gtcggctgga cacgttgccc ggcatgaccg
    12181 tgggattgta tccgctacga ccggaatcca cgggtagcat ccacattcgt tctagcgatc
    12241 cggcggttgc gccggtcatt gagtcccggt ttctagaaca tgaggatgat cagcggcgga
    12301 tgattgcggg aatgcgcatt ctacgggaga tcgccgccca accggcattg cgagcctact
    12361 gcgaccacga gttgtcgccg ggaaccgagg tcgagtcaga cgaagaattg ctggagtttg
    12421 cccgcaccca aggcgatacc tcttaccacc cggtcggcac ctgtcgcatg ggcaaggatg
    12481 agctggccgt agtcgatcac cgtctgcgtg tgcatggcct tcaaggtctg cgggtgatcg
    12541 acgcatcgat aatgccgacg atggtctcgg gcaacaccaa cgctgcgtcc ctgatgatcg
    12601 ctgagaaagg cgcggatatg gtgctacagg attatgcatc gtcgtcaatg tctaggcagg
    12661 agctatttag catcgttgaa ggcgatccag aggagcagca ggtcgctgca ctgctgcaac
    12721 gatcagaaga ttacgcacgc tcgctgtatc ccgctgaaag tgtgcacatg ctcgacgtag
    12781 cgcagctcaa ggcgccgggt gtcagcttcg tagtcgcgcg agaatttaat agcggcgagg
    12841 tgctcggctg cggtgcggtg gtgaacatcg gcaatggcga ggcagagctc aagcgtatgt
    12901 tcgttgccga caacgcgcgc cgtcgtggag ttggtgtgcg cttgctcaag cgtctggagc
    12961 atcttgctcg gcgcaacggt gccagaacac tgctgctgga aaccggtgta agtcagcctg
    13021 aggcgatttc gctctatcgt ggcgcgggtt ttcgtgatcg tggtcccttc gccgattatc
    13081 aagaagaccc gctgagcgta tttatggaga agactatcga tgaacaagcc tgaagcaagc
    13141 ctgattggcc ccgttacacc ggtcagccgc tgggtcgggc gggcgggaat tttgtatgta
    13201 gcagcgttct tagtgctggc taacgcgaac gccgtcttct ccggcaacct gctccagcag
    13261 ctgcatccgt tcaccttcct gttctggaat ttcgtcataa ccagcggttt ctttctgact
    13321 cgcttgttgc tcagttccgg tactagtgga ctggcgatcg aaggccgcgc cgcaggcccg
    13381 ctaaccgttc tgaatttcac cagtgccctg aactggatcg gttatttcta tgccttgcgc
    13441 tatattgaac cggcgatcgt cagcgcaatt atgggcggac ttggcccagt gagtacgatc
    13501 ctcctagagc gggtggtgcg tcgaagacag ctgccgcttt acacctacgc tgtggcggca
    13561 ggtatcctat ccggtacggc attactggca tgggcgtctt tggtggggct ggcgggaatt
    13621 cgtccgatca atttcagtga taccctgatc ggcctcgctg cagcggcggc cggtggtgca
    13681 tctcaagcac tgaataccat cgcgactaag caactgggtg agcgcagttg gaccgccacg
    13741 cgaatcatgg cccaccgttt ctacctgctt atcattgtcg ccgcagctct aacctatagc
    13801 ggcccaggct ttgcgatcgc ctccagcacg caagtcggtg gcttggcaat tgcaaccctg
    13861 ctcggcgtga tcattccatt gtggttactg cagcgtggca tcctgctttc ggaacccttc
    13921 accgtggcag cgctgctcgc gtgggcaccg ttgctcactt acgtctttca agtattcgat
    13981 gcgcgaatcc agtggtcaat gacctctgcg ttgggctgct ccgtgatcgc tttggtcacg
    14041 gtgtttggca catggatgaa attcaaagga gatagaaaat gacgcaagcc aaggaaaata
    14101 tcctggtggt agtcgatggt tattcatcgg gctctcaact accgacgctg atggccgagt
    14161 ccggctggaa gtgcgtacac gtgagcagtt cggccaaccc cccggaatac tatctgcgca
    14221 cttatcacaa ggatgagtac atcgcgcact tcgagtatca aggtgacatc cagtcgctgg
    14281 cctccgccgt agaagcttgg catccggcgg cggtactgcc ggggaccgag agcggggtca
    14341 tagtcgccga ccttttggcc gcagcccttc aactgcccgg caacgacccg tcgaccagtc
    14401 tggcccgacg tgacaaatat acaatgcacg agagcctaaa ggctgtcggc cttcgcagca
    14461 tggatcattt tctggctgtt gaccgcgatg ccctgagcgc gtgggccgag cgcggctctt
    14521 ggccggtggt gatcaagcca caagccagtg caggtaccga ctcggtgact ttttgtgctg
    14581 atcagggcga actgctcgaa agcttcgacc agctgttcgg aacagtcaat caattgggtg
    14641 aacgcaacaa cgcggtccta gcgcagcgct tgctggtcgg tccggagtat tttatcaatg
    14701 gcgtcagcgg ccatggcaaa catttgatta ctgaaatctg gcgcgccgac aagctgccag
    14761 cgccagacgg cggctggatt tatgaccgtg ccgtgctgtt tgatcctact tcgccagaaa
    14821 tgcaggaaat cgtcaggtat gtgcacggcg tgctggacgc cttgggcatc cgttacgggg
    14881 ccaaccacac cgaattgatc gtgactgccg acggcccgac actgatcgag tgtgcctcgc
    14941 gtttgtccgg cggattgcat cgtccggcgg ccaactatgc ggtcggcgcc agccagttgg
    15001 atctggtggg caaactggtc agggaagggg agtcggcaat cgatgacatt ctccagacct
    15061 ggcaacccca tcgctatgcg ctgtggcagg tgcagttcat ctccaaccaa gaaggtgtag
    15121 tcgcgcgctc ctcgtacgac gaattgctca agacgctaaa aagcaatgcc tggcttcagc
    15181 gtgcgccgaa agaaggcgac actgtggtca agacggtaga cctgttttcc agtcccggta
    15241 ttgtgttcat gagtcatgcc gacggcaatg ttctgcatga cgactaccgg accgtgcggg
    15301 agtgggagcg cacctctcgc ctgttcagcg tccaataacc ttttgaaggt aactgcgcat
    15361 cgggcctgct gaagggcccg gtacgccacc atattcaaac ccccgtacga agggtttcgc
    15421 gtctacgtct ggaaatcatc gccatgaagc caatggattc gcagcggcag cagcgcagga
    15481 tgctgctggc cgtaggtata ggcacgaccc tggagtggtt cgacttcacc ttgttcgcga
    15541 tcttttctct gcacatcgcc aagatcgtct tcccggccca agatcaattg atgtcgctgc
    15601 tggccacctt tgtcaccctc gcggtgggct ttgttgcgcg accgctgggt gcgtttctca
    15661 tcggtcgcta tgccgatcgt catgggcgca agaaagcgct gattttgacc atgaacatga
    15721 tggccgccgg caccgtgatg attgccctct gtcccggcta cagcatgctg ggctatggcg
    15781 ccacggtgct gctggtggtg gcgcggatcg ttcagggcct ggcggcgggg ggcgaaatcg
    15841 gcagtgcgct ggcctacctg tgcgagtcgg caccggtttc gcgcaggggc ttttttacct
    15901 ccttccagca agtcgcgcag gcaggttcct ttttgctctg cggcttgttc gcgagcatcc
    15961 tggcaacggt gctgacgcct gaacagctcg gcagctgggg ctggcgtatt ccgtttgtcc
    16021 tcggcgtgtt catctatttg gtgggtgtct atgtgcgccg gaccatcaac gagagccatg
    16081 agttccaagc ccatgcccgc gagggagtag aggtgcccgc ccgggaaatc cttaggcact
    16141 ggcgcagcct tgtcctagga atcggctttg ttgccttgtg gacggtatgc acccaactga
    16201 tcaatttcat gcctgcctac gcccaagcca tgttcaactt ggatgcaggg aaagcctatt
    16261 acggaatcac cttggtcggt tttatcacct tgctcagccc gttgggcggc tggctgtcgg
    16321 atcgttgggg gcgatataac gtcatgctgc tcggcgcgct gggggtattg atgctggcgt
    16381 acccggcatt tctggcactc aagcataatc cgcaggatat gggcttgatg ttgctgcaag
    16441 ccgggcttgc cgtatttatg gtgttgtacg ccggcccggc gtcggcagcg ctggccgaac
    16501 tattccctgt ggcagtgcgc tcgacgggca tcagcgtggc ctacgccagt tccgtgttgt
    16561 tgttcggcag tttcacacca atgctggtga ctttgctcta ccgctatacc ggtgacccga
    16621 tgatggccgc gtattatttg ctagcagctg cgctggtgag ctttttcgct ttagtgatag
    16681 cgcgtcagtc gcaggtttca ttcgtcggca ggttgatttc taaagggaag caggttgagt
    16741 attagagggg aaaagtctat aaatgatgtc agagcgacac gtttgattga gtcacgaggt
    16801 ggctatgacc acaaacgcta aaagagatga cagcgctgca atgcgtatcg ggcaaagctt
    16861 gggacgtggt gtggctggag tgttgcgtct ggaaaaagca ttgtggtcat cgtcgattat
    16921 tgccggtttg cctaggccga ttattagccc tatcaagtgg gccgttcgcg tggcggtgat
    16981 cggtggtggt gtattctttg ctgcatgggg gctgttatac gttttggcgg tcgtgtgctt
    17041 tcttgcaata gctatcggtt ttgtcaccaa ccctgggatt gagcgcggat tgcgtggctc
    17101 acaactcgtt cattttgacc aagcctcgga agatgcatct ggtatgggcg agtcggggtg
    17161 gatgagtggg ccacaaggtt atggctacta cgaaaatggt ttgaaacagc agtgagttag
    17221 ctaggagctc gatgccaagt gctggtaact cggcatcgag gatcttcgta cctatttctt
    17281 catcagcgac atgattatat ttgcaccgcc gcctcccgcc gatttggcgt cccttgtacc
    17341 ttcagtcaag ccttgcataa ggccaccaat agtcgcacct ccccatccca acgcaagtac
    17401 ccagaaactt gggagcacga tgaacattgc gcccatcaca aagtccagca gtaggtctcc
    17461 ttgggcattg ctggccccaa acactgggtc aaaattggag tgggggacgt tgctgccgat
    17521 cccgttacca taaagggcgt ctaaaatcgt gctgtctacc cagcgggcca actggaacca
    17581 gaagtcgaca aagatcaaag cgaacgcagc aaaagtaatc gtcatcacga ccttcagatc
    17641 aaacattccg attaccagca cgaatggaat gcagattatg agagccatct tcaggaaggc
    17701 catcaccatg ggcgctgcct gccttacact gtccatggct ggatacatca caagagatcc
    17761 tgctgcctga ccagctgtag ctgcaaggcg tgtgaagtca ttcagcacag agccaccgac
    17821 ttgaccgcca tagtccgagt acacctgtcc ttgggtcagt tgctgcttcc tcggggagac
    17881 cagatctcga atgaccgagt cgctgacttc ggtctgggtc atgaactttg cccactgagc
    17941 aagcttgctc agcagatctg gactgacctg ttccagcagc ctggctctaa gcccgacgct
    18001 tccatccgac caccattgag tgcatgtggg aaatccacca ccaccagtgg tttgtggcag
    18061 gccagcgtcc cgggttgcgt catagggcca tttggttcga ggagtgtgtg acctgaatcc
    18121 agagaagcca tcgctgtaat agccggatgt ttgcaggaag aagtgcgaac cgatccagtt
    18181 gacgtcgttg agttgatcat tgctgagggt aggctgggtc atgaaaagct ttgcgcgagc
    18241 gcgcgcgtag caatcgttcg tgaagtcagc cacctcctgg gcaagcagtg gatcgttgat
    18301 gcgggccttg ttgacgtcca tccggacctg ttgcaaatcc actccacagg gaatagctgc
    18361 gactgaggca gcagttgctg ccttcgacat cgcatgcaca aacagccacc agacgggcac
    18421 tgtggcgctt ttaccgttca gcgtactgaa ggatgtttcc cagcccgtat cagtcggatt
    18481 gggtattgag tattggcact gctctgagcg gcttcggtcg aactggatgg tatcaatgct
    18541 gacgtttacc agaggcatgc aagccaggat gatgactagg attgccgtgt agaaccggtt
    18601 ttctactcgg gccaacgaga ggacaccctt gttgccctca tcagctccct caccgcgggc
    18661 tctgagccat tcgctgatga caatggccgc aaaaggggcc gcgaatagtc cgctgtcctc
    18721 gatcatgttc cagatgccgc tgttgatcag ccatccgacg agtgtcaggt aatactcaag
    18781 gtagtcattc gtgtgcaaga tcatggcagg tcaactcccg ctacagtggc agcgcgccga
    18841 agctcgaaaa ggagaatgac gaagatggcc atgacctcgc aacgacgaag tcccgagggg
    18901 aatagatttg tgtctgatgc tcgctgttta agggtgcgtt ttagcctgta ccagccaagc
    18961 cctatcgctg cataaagcga cagccgccag gccagcatgt agttgtagtg cgctttttgc
    19021 cattccctga actgctcaat atctccaaag aaatgcgcga tggctgtcat gaaattcaca
    19081 gccagaacaa tggtcagcac gaccggccag gtgaatgaaa ccagcgcttt cgcgccccta
    19141 cgtagccatc ccttggcaac cggcgatgaa ctcatgatca gttacctttc gcagggttct
    19201 gcagctgctc gaggcggtca ggcgttggat cgccttgaaa gatgcccttg gagctgtcct
    19261 tccggctctg agctctctgt agaatggctg tcggtgagtt gctggccagg ttgcgacgca
    19321 tatccagctc ggtcttcagg ttgtcaattt cctgttgcag gctgctgttc tgctgactga
    19381 ccgcctgcag ggccacatcg ttggcggcaa tgttcggctc tttgcttccg gtgaacatgg
    19441 tgcgctgaag cagtagcgct ttgccgagaa cctcagataa agcgacctct gaagcaagac
    19501 gttttgcgag gatatcttgg tcatgctcag tccttagtgc ctcgaccact ccacgggtaa
    19561 caggcagaga atcgctgctc gctgcagtca agttttccga ggtgagcgct ttgctgcccg
    19621 agatcaattc ctgcagcgcc tttagcttgg agtcgtagga ttcctggatg agaggagtga
    19681 gcccaacgcc ggcagtggac gtcgttttgg tgcaatcctc gcaagtgcgt tgttgttgct
    19741 ctcccagtac acgattggcg aaagtggtag ctgcctgagg cgatgaccag gtggaacaca
    19801 ccatgccgtt gttgcaggcc gaaggactaa tggacgatgt atcggcagcg ccgcgtccgt
    19861 tcagcaagtt gtatcccgca cgggtaacgt cgcctacaac cttgataggt tgctggccag
    19921 atccgccggc cttatttcct ccgagccacg taataccgtc attccctccc tgcttttcga
    19981 cctgtgcaac ggctgataca gcatctgtgt tcccgttttt caccgcctga ctcatagcct
    20041 ggccctcggc gatcttgttc cagcccatct gtcctccggc gacatcgagc atcttgtcag
    20101 caatggcacg gcaagtgcct ttggagcggt cgaagtcaag acgaccctgc agaatgccgt
    20161 tggtgagcag gttgtacaaa gccggattag cccgctggat aatcaggcct ggtagtgatg
    20221 aaacggcgct ggtagcgttt gaaatcatcg accccatgat cgtctgaaat ccggaggttg
    20281 ctccattcaa ctgattctgg agcgtgttgt tcatgctcat gtttccgcag accaggttgc
    20341 tgttccagcc accgccgatg ctgatgctat ccatattccc cgccgtaccc atcgtcacag
    20401 cgttgccgcc tccaacgctg taaaagcacg tcgtcaccga tcacgctgcc cgatgagctt
    20461 gcattgattc ccgggatttc ggcgaaagca ctatgggctg tcagggtgct catgaatgcg
    20521 atagtcagaa aggcagcgcg gcgcatagtt gaagtcctct tgatcatcat tgaaagtccg
    20581 tactgccaag aaaggtttgt ccttcccgct tgcagcagga atacggccgc cataacgccc
    20641 aggcgtaacc accatcggtt gcctgcacac ggggctggga gtttggaaat accgcgcagc
    20701 tttgactgag ggtcggcgtc agctcttgcc acttaccggt ggtggcgtcg gtctcgatca
    20761 attctccagc aggccaatag cctggctggg gctgtgccag aagcggttga tagacatgaa
    20821 cctggccgct gcgagtgacc acgtcaccag cacgctgcgc gatcacggat gccgccttgt
    20881 aatcgtcggc ttgatggata aaaccactgc gagggtagac gcttccccac atgtcccccg
    20941 acgtcagacc acccacctct cgacggccgg gaataagtgc ttctggatac actgattctg
    21001 gaactccgta acgccaggcg acggtgtcca aggtgctcag caggtagggc atgtagggcg
    21061 tggcagcgcc ctgacaggca taacccgagg cgctggcaaa tttactgaat gttgctcctc
    21121 cggggtggcc tatgacgtca gcgtttttga atttagccag gctatcttcg ttgttgtgat
    21181 tggtggtccc gtcgccgcca gcttgggcaa atgaagtggg cgagctcacc gaagagacct
    21241 caatccaggg gttttcaccg gtattcgaat agcttgagac cacggcgtct ggaacgaagt
    21301 gacgaacctt ggtcgacgtc ttcaccttgc atccaaacgg ggtgcaaagc agccagtaac
    21361 agatcccgac caccttgtat tccaggcagt caggcgacag ggatgaggcg accagggtgg
    21421 cagatgtcac cgtgcccgct gctgtcggcc aggttgagat cgacaatgct aaggctgccc
    21481 atgctggagg ctttcgcagg ttcatcgcgg cgcatctccc tggccagatg cgttctgata
    21541 tttggcggcg gtgcgccact ggacaatgcg atattcagcc gccgtagcgt tcgtttcccc
    21601 gtacaccaca aacttgcggt cgaccaccac agcaggcacc ttcgttaccc ccatgctcca
    21661 ggcgtctact aggtcttgtt gagccaatgc cagatctcgt tgcaagcgct gcgcatcgct
    21721 gctcttgagg cgttgctgca tgattgagat ggcttgttgc tgattcgccg gcagtccttc
    21781 agagagcttg gcctcaagtc gttctgattc gtccaggagg atcagccgga catgtgccgg
    21841 tgtctggact ggatggttcc ggtcagtaac gatcgacgtc tccgcgctcg agaaggggac
    21901 ctgtatggcc gcaatcaaga tcaggaaggt catgctgttc ttgcgtttga agcgataggg
    21961 gctggagggg gacattaggc agtacctgca ggtggtgtca ggtacagaaa acgcgattaa
    22021 tgaactgtcg tctgtaggaa accgttatcg ggacggttgg ggtttgatgg cgtctgcgag
    22081 ggccgagcgg ccgccatcga gcagcaggcg cggtagtggt ttaggtaaac agcactacaa
    22141 gcgggcctgt aaggcatacg tcatgtgctg cgagccggtt atcatggtgg aggatgtctc
    22201 gggtgctgta tcccttgacc actgcactgt tgttgctggg cacgcagttg cataggacac
    22261 ccagcgccta ccgccggcct ggctgccgct cagcttcact ccaagccccg cttcgtgcgg
    22321 ggcttggcca gtagaaacac acgacttttg cactaaaaag acacaaggaa cgtcttatga
    22381 aattagaagt gagtcaattg attgcggttt tggcttctat tggtctggga gaagcagggc
    22441 agcgcactgc agatcctttc tacagcgagg catttattat tgctctgctc ttgggatttt
    22501 ttctgatgat ggcagctctt gcgcgcgagg tctttgaagt gctgcgtgaa aagtcattga
    22561 tttgatgctg agtgccgtag agcgtcttaa gcagagtcaa gggtagttga tcaggtctta
    22621 ggttgatagg gcggggtcaa ttgtggcaga agtagaaagc gattttcgct tacttgttga
    22681 tacgaatagg aatgtcatgg ctactcacaa agaactcgtt gctgaactga tcaatgtact
    22741 gaactctgat ggctcatccg aagttcgagc tggggccgca aagggactag gcgctgctgg
    22801 tggtgctgat gcattgcgcg ctctgcgtgc agcgctgaag catgatagta agattttggt
    22861 tcgcgccaca tctgcggagg ctgtcggttt gattcttggg cgtggcaatt tgcaggacat
    22921 gatggatcag tgattccgaa cagactcggt tcgccgagct tgtagatagc cg
//
