BGC0000847: thienamycin biosynthetic gene cluster from Streptomyces cattleya
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Location: 1 - 32,329 nt. (total: 32,329 nt).
This entry is originally from NCBI GenBank AJ421798.1.

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core biosynthetic genes
additional biosynthetic genes
transport-related genes
regulatory genes
other genes
resistance
TTA codons
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Gene details
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General
Compounds
Genes
Biosynthesis
History
KnownClusterBlast
General information about the BGC
MIBiG accession BGC0000847
Short description thienamycin biosynthetic gene cluster from Streptomyces cattleya
Status Quality: questionable
The quality level of this entry.

Status: active
The status of this entry.

Completeness: complete
Whether the entry covers everything needed for the pathway producing the compound(s)
Biosynthetic class(es)
  • other (non-nrp beta-lactam)
Loci
AJ421798.1
via Knock-out studies
Compounds
  • thienamycin
Species Streptomyces cattleya [taxonomy]
References
Chemical products information
thienamycin Evidence:
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C11H16N2O4S1
Chemical database entries
NPAtlas
List of genes involved in compound(s) production
Identifiers Position Product Functions Evidence Extra
  • CAD18967.1
 1 - 751 (-) hypothetical protein
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    • CAD18968.1
    		 1034 - 1924 (+) hypothetical protein
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      • CAD18969.1
      		 1940 - 2719 (-) putative oxidoreductase
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        • CAD18970.1
        		 2850 - 3932 (-) putative lactone-dependent transcriptional regulator
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          • CAD18971.1
          		 4117 - 4755 (+) putative lactone efflux transmembrane protein
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            • CAD18972.1
            		 4945 - 6036 (+) putative oxidoreductase
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              • CAD18973.1
              		 6288 - 7172 (+) enoyl-CoA hydratase carB homologue
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                • CAD18974.1
                		 7156 - 8139 (-) hypothetical N-acetyltransferase
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                  • CAD18975.1
                  		 8136 - 8927 (-) putative hydroxylase
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                    • CAD18976.1
                    		 9171 - 9845 (+) hypothetical protein
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                      • CAD18977.1
                      		 9767 - 11197 (-) transcriptional regulator ClaR homologue
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                        • CAD18978.1
                        		 11289 - 12740 (-) putative transport protein
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                          • CAD18979.1
                          		 12737 - 14782 (-) putative methyltransferase
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                            • CAD18980.1
                            		 14838 - 16262 (-) putative methyltransferase
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                              • CAD18981.1
                              		 16234 - 17610 (-) putative beta-lactam synthetase
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                                • CAD18982.1
                                		 17612 - 18715 (-) hypothetical protein
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                                  • CAD18983.1
                                  		 18754 - 20172 (-) putative oxidoreductase
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                                    • CAD18984.1
                                    		 20169 - 21623 (-) putative methyltransferase
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                                      • CAD18985.1
                                      		 22038 - 22817 (+) putative oxigenase
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                                        • CAD18986.1
                                        		 22912 - 23634 (-) hypothetical protein
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                                          • CAD18987.1
                                          		 23744 - 24733 (+) putative beta-lactamase
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                                            • CAD18988.1
                                            		 24784 - 25983 (+) putative cysteine transferase
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                                              • CAD18989.1
                                              		 26146 - 26952 (+) transcriptional regulator ccaR homologue
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                                                • CAD18990.1
                                                		 26980 - 27393 (-) putative cysteine transferase
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                                                  • CAD18991.1
                                                  		 27614 - 28156 (-) hypothetical protein
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                                                    • CAD18992.1
                                                    		 28224 - 28412 (+) hypothetical protein
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                                                      • CAD18993.1
                                                      		 28485 - 29246 (+) hypothetical protein
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                                                        • CAD18994.1
                                                        		 29382 - 29567 (+) hypothetical protein
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                                                          • CAD18995.1
                                                          		 29766 - 30197 (+) hypothetical protein
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                                                            • CAD18996.1
                                                            		 30695 - >32329 (+) hypothetical protein
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                                                              Biosynthesis information
                                                              Annotation changelog

                                                              Entry version: 3

                                                              Date
                                                              Changes
                                                              Submitters
                                                              Reviewers
                                                              2022-10-07
                                                              Update chemical activity to schema version 2.11
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                              Entry version: 2

                                                              Date
                                                              Changes
                                                              Submitters
                                                              Reviewers
                                                              2019-10-16
                                                              Migrated from v1.4
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              2019-10-16
                                                              Updated compound(s) information (NPAtlas curation)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)

                                                              Entry version: 1

                                                              Date
                                                              Changes
                                                              Submitters
                                                              Reviewers
                                                              2015-06-12
                                                              Submitted
                                                              • (ID: IROSGRAECON7XFWB774QFHDN)
                                                              • (ID: AAAAAAAAAAAAAAAAAAAAAAAA)
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