Genomic loci for this biosynthetic pathway

Cluster Type From To
The following clusters are from record BGC0000847.1:
Cluster 1Other132329

BGC0000847, thienamycin biosynthetic gene cluster from Streptomyces cattleya. Locus 1. Full MIBiG entry.

Chemical compounds

Compound: thienamycin
SMILES string: Copy to clipboard
Molecular formula: C11H16N2O4S
Exact molecular mass: 273.32 Da ([M+H]+)
Molecular activity: Antibacterial
Molecular target: bacterial cell wall biosynthesis (peptidoglycan)

Class-specific details

Biosynthetic class(es):
Other
Other biosynthetic class:
Non-NRP beta-lactam

Gene cluster description

thienamycin (BGC0000847). Gene Cluster 1. Biosynthetic class = Other. GenBank AJ421798. Click on genes for more information.

Legend:

biosynthetic genes
transport-related genes
regulatory genes
other genes

Homologous known gene clusters

General MIBiG information on this cluster

Complete gene cluster sequence?complete
Evidence for cluster-compound connection:Knock-out studies, Sequence-based prediction
MIxS-compliance:Unknown
Contact for this cluster:Jose A. Salas (University of Oviedo)

Literature references

1. Nunez LE et al. (2003) The biosynthetic gene cluster for the beta-lactam carbapenem thienamycin in Streptomyces cattleya. Chem Biol 10(4):301-11.